IINUMA TOMOHISA 飯沼智久

… Alternative Names

Iinuma Tomohisa 飯沼智久

飯沼智久イイヌマトモヒサ

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Researcher Number	00748361
Other IDs	https://orcid.org/0000-0002-9940-5520
Affiliation (Current)	2025: 千葉大学, 医学部附属病院, 講師
Affiliation (based on the past Project Information) *help	2022 – 2024: 千葉大学, 大学院医学研究院, 助教 2018 – 2019: 千葉大学, 大学院医学研究院, 助教 2015: 千葉大学, 医学(系)研究科(研究院), 特任助教
Review Section/Research Field	Principal Investigator Basic Section 56050:Otorhinolaryngology-related / Otorhinolaryngology
Keywords	Principal Investigator T細胞 / 花粉症 / アレルギー性鼻炎 / シングルセル / 舌下免疫療法 / 感作未発症 / アレルギー

Unraveling the Mechanism of Action of Sublingual Immunotherapy Using Single-Cell AnalysisPrincipal Investigator
- Principal Investigator
  
  Iinuma Tomohisa
- Project Period (FY)
  2022 – 2024
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Review Section
  
  Basic Section 56050:Otorhinolaryngology-related
- Research Institution
  Chiba University
Investigation of the onset of Japanese cedar pollen induced allergic rhinitis from the point of the Asymptomatic sensitization stage and the T cell functionPrincipal Investigator
- Principal Investigator
  
  Iinuma Tomohisa
- Project Period (FY)
  2018 – 2019
- Research Category
  
  Grant-in-Aid for Early-Career Scientists
- Review Section
  
  Basic Section 56050:Otorhinolaryngology-related
- Research Institution
  Chiba University
スギ花粉症の感作・発症因子とPathogenic T細胞の機能との関連Principal Investigator
- Principal Investigator
  
  飯沼智久
- Project Period (FY)
  2015
- Research Category
  
  Grant-in-Aid for Young Scientists (B)
- Research Field
  
  Otorhinolaryngology
- Research Institution
  Chiba University

All 2025 2024 2023 2022 2019 2018 2016 2015

All Journal Article Presentation

[Journal Article] Adherence to Treatment in Allergic Rhinitis During the Pollen Season in Europe: A MASK‐air Study2025
- Author(s)
  Sousa‐Pinto Bernardo、Costa Elsio M.、Vieira Rafael Jos、Klimek Ludger、Czarlewski Wienczyslawa、Pfaar Oliver、Bedbrook Anna、Amaral Rita、Brussino Luisa、Kvedariene Violeta、Larenas‐Linnemann Desiree E.、Iinuma Tomohisa et al
- Journal Title
  
  Clinical & Experimental Allergy
  
  Volume: 55 Issue: 3 Pages: 226-238
- DOI
  10.1111/cea.70004
- Peer Reviewed / Open Access / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-22K09739
[Journal Article] Concepts for the Development of Person-Centered, Digitally Enabled, Artificial Intelligence?Assisted ARIA Care Pathways (ARIA 2024)2024
- Author(s)
  Bousquet Jean、Schnemann Holger J.、Sousa-Pinto Bernardo、、Iinuma Tomohisa, Ohta Ken、Okamoto Yoshitaka
- Journal Title
  
  The Journal of Allergy and Clinical Immunology: In Practice
  
  Volume: 12 Issue: 10 Pages: 2648-2668.e2
- DOI
  10.1016/j.jaip.2024.06.040
- Peer Reviewed / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-22K09739
[Journal Article] A case of IgG4-related disease with laryngeal lesions that was difficult to diagnose2024
- Author(s)
  Fuse Hiroki、Iinuma Tomohisa、Kameda Akane、Kishino Aiko、Takeda Yoritaka、Hiramoto Takuto、Arai Tomoyuki、Yamasaki Kazuki、Yonekura Syuji、Hanazawa Toyoyuki
- Journal Title
  
  JOURNAL OF JAPAN SOCIETY FOR HEAD AND NECK SURGERY
  
  Volume: 34 Issue: 2 Pages: 217-223
- DOI
  10.5106/jjshns.34.217
- ISSN
  1349-581X, 1884-474X
- Language
  Japanese
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-22K09739
[Journal Article] Factors contributing to the diagnosis and onset prediction of perennial allergic rhinitis in high-risk children: A sub-analysis of the CHIBA study2024
- Author(s)
  Yonekura Syuji、Okamoto Yoshitaka、Yamaide Fumiya、Nakano Taiji、Hirano Kiyomi、Funakoshi Urara、Hamasaki Sawako、Iinuma Tomohisa、Hanazawa Toyoyuki、Shimojo Naoki
- Journal Title
  
  Allergol. Int.
  
  Volume: 73 Issue: 3 Pages: 436-444
- DOI
  10.1016/j.alit.2024.01.012
- ISSN
  1323-8930, 1440-1592
- Language
  English
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-22K09739
[Journal Article] Perceptions of the impact of individual allergic rhinitis symptoms: A survey of ARIA clinical experts2024
- Author(s)
  Gil-Mata Sara、Teixeira Tatiana、Bedbrook Anna、Bousquet Jean、Iinuma Tomohisa、Ohta Ken、Okamoto Yoshitaka、Okubo Kimihiro
- Journal Title
  
  World Allergy Organization Journal
  
  Volume: 17 Issue: 12 Pages: 100999-100999
- DOI
  10.1016/j.waojou.2024.100999
- Peer Reviewed / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-22K09739
[Journal Article] Differences in the expression of multidrug resistance proteins in chronic rhinosinusitis according to endotype2023
- Author(s)
  Iinuma Tomohisa、Yonekura Syuji、Hirahara Kiyoshi、Kurita Junya、Yoneda Riyo、Arai Tomoyuki、Sonobe Yuri、Shinmi Rie、Okamoto Yoshitaka、Hanazawa Toyoyuki
- Journal Title
  
  Allergol. Int.
  
  Volume: 72 Issue: 4 Pages: 564-572
- DOI
  10.1016/j.alit.2023.03.008
- ISSN
  1323-8930, 1440-1592
- Language
  English
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-22K09739, KAKENHI-ORGANIZER-21H05120, KAKENHI-PLANNED-21H05121, KAKENHI-PROJECT-23K27607
[Journal Article] Pathogenic helper T cells as the novel therapeutic targets for immune-mediated intractable diseases2023
- Author(s)
  Onodera Atsushi、Kokubo Kota、Okano Mikiko、Onoue Miki、Kiuchi Masahiro、Iwamura Chiaki、Iinuma Tomohisa、Kimura Motoko Y.、Ebihara Nobuyuki、Hanazawa Toyoyuki、Nakayama Toshinori、Hirahara Kiyoshi
- Journal Title
  
  Pharmacology & Therapeutics
  
  Volume: 247 Pages: 108445-108445
- DOI
  10.1016/j.pharmthera.2023.108445
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-22K15485, KAKENHI-PROJECT-22K09739, KAKENHI-PROJECT-22K15484, KAKENHI-ORGANIZER-21H05120, KAKENHI-PLANNED-21H05121, KAKENHI-PROJECT-23K24147, KAKENHI-PROJECT-23K27607, KAKENHI-PROJECT-19H05650
[Journal Article] Single-cell immunoprofiling after immunotherapy for allergic rhinitis reveals functional suppression of pathogenic TH2 cells and clonal conversion2022
- Author(s)
  Iinuma Tomohisa、Kiuchi Masahiro、Hirahara Kiyoshi、Kurita Junya、Kokubo Kota、Yagyu Hiroyuki、Yoneda Riyo、Arai Tomoyuki、Sonobe Yuri、Fukuyo Masaki、Kaneda Atsushi、Yonekura Syuji、Nakayama Toshinori、Okamoto Yoshitaka、Hanazawa Toyoyuki
- Journal Title
  
  Journal of Allergy and Clinical Immunology
  
  Volume: 150 Issue: 4 Pages: 850-860.e5
- DOI
  10.1016/j.jaci.2022.06.024
- Peer Reviewed / Open Access / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-22K07164, KAKENHI-PROJECT-22K09739, KAKENHI-PROJECT-22K15484, KAKENHI-PROJECT-22K15485, KAKENHI-ORGANIZER-21H05120, KAKENHI-PLANNED-21H05121, KAKENHI-PROJECT-19H05650, KAKENHI-PROJECT-20H03685, KAKENHI-PROJECT-21K20754
[Journal Article] Complement Factor H Is an Early Predictive Biomarker of the Therapeutic Efficacy of Sublingual Immunotherapy for Japanese Cedar Pollinosis2022
- Author(s)
  Yoneda Riyo、Iinuma Tomohisa、Sakurai Daiju、Kurita Junya、Arai Tomoyuki、Sonobe Yuri、Yonekura Syuji、Okamoto Yoshitaka、Hanazawa Toyoyuki
- Journal Title
  
  Pathogens
  
  Volume: 11 Issue: 11 Pages: 1280-1280
- DOI
  10.3390/pathogens11111280
- Peer Reviewed / Open Access / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-22K09739, KAKENHI-PROJECT-22K16924
[Presentation] スマートフォンアプリMASK-airからみる年間の鼻アレルギー症状変化と関連2024
- Author(s)
  飯沼智久　栗田惇也　山崎一樹　米倉修二　花澤豊行
- Organizer
  第63回日本鼻科学会総会・学術講演会
- Data Source
  KAKENHI-PROJECT-22K09739
[Presentation] デジタル技術を利用したアレルギー診療と研究2024
- Author(s)
  飯沼智久
- Organizer
  第54回日本職業・環境アレルギー学会総会・学術大会
- Invited
- Data Source
  KAKENHI-PROJECT-22K09739
[Presentation] Multidrug resistance proteins are expressed in different degrees and types depending on the endotype of chronic rhinosinusitis.2024
- Author(s)
  Tomohisa Iinuma
- Organizer
  ISIAN-IRS 2024
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-22K09739
[Presentation] スマートフォンアプリMASK-airから見るアレルギー性鼻炎の薬剤使用状況2024
- Author(s)
  飯沼智久　新見理恵　栗田惇也　新井智之　米倉修二　花澤豊行
- Organizer
  第4回日本耳鼻咽喉科免疫アレルギー感染症学会総会・学術講演会
- Data Source
  KAKENHI-PROJECT-22K09739
[Presentation] Association of musculin expression on Th2 cells with the effect of sublingual immunotherapy2023
- Author(s)
  Tomohisa Iinuma
- Organizer
  Korean Academy of Asthma Allergy and Clinical Immunology International Congress
- Invited / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-22K09739
[Presentation] アレルゲン免疫療法による免疫修飾2023
- Author(s)
  飯沼智久
- Organizer
  第10回総合アレルギー講習会
- Invited
- Data Source
  KAKENHI-PROJECT-22K09739
[Presentation] Sublingual immunotherapy for children with allergic rhinitis in Japan2023
- Author(s)
  Tomohisa Iinuma
- Organizer
  16th Taiwan Japan Conference on Otolaryngology Head and Neck Surgery
- Invited / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-22K09739
[Presentation] モバイルアプリを使用したアレルギー疾患の動態調査（MASK study）2023
- Author(s)
  飯沼智久
- Organizer
  第72回　日本アレルギー学会　学術大会
- Invited
- Data Source
  KAKENHI-PROJECT-22K09739
[Presentation] 舌下免疫療法を行うことでT細胞にどのような変化が起きるのか2023
- Author(s)
  飯沼智久　栗田淳也　新井智之　山崎一樹　米倉修二　花澤豊行
- Organizer
  第62回日本鼻科学会総会・学術講演会
- Invited
- Data Source
  KAKENHI-PROJECT-22K09739
[Presentation] 舌下免疫療法の効果とTh2細胞におけるMusculinの発現の関連2022
- Author(s)
  飯沼智久　栗田淳也　新井智之　山崎一樹　米倉修二　花澤豊行
- Organizer
  第61回　日本鼻科学会　総会・学術講演会
- Data Source
  KAKENHI-PROJECT-22K09739
[Presentation] Single cell immune profiling detected sublingual immunotherapy-induced changes in T cell population.2022
- Author(s)
  Tomohisa Iinuma
- Organizer
  2022 ANNUAL CONFERENCE OF CHINESE COLLEGE OF ALLERGY AND ASTHMA
- Invited / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-22K09739
[Presentation] 舌下免疫療法によるTh2細胞の機能抑制と抑制性T細胞への分化の可能性2022
- Author(s)
  飯沼智久　栗田淳也　米田理葉　新井智之　米倉修二　花澤豊行
- Organizer
  第71回　日本アレルギー学会　学術大会
- Data Source
  KAKENHI-PROJECT-22K09739
[Presentation] Single cell immune profiling after sublingual immunotherapy for allergic rhinitis2022
- Author(s)
  Tomohisa Iinuma
- Organizer
  European Academy of Allergy & Clinical Immunology Hybrid Congress 2022
- Invited / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-22K09739
[Presentation] Pathogenic Th2 cells develop the symptoms of Japanese cedar pollen-induced allergic rhinitis2019
- Author(s)
  Tomohisa Iinuma
- Organizer
  2019 KAAACI-KAPARD-WPAS-INTERASMA Joint Congress
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-18K16874
[Presentation] スギ花粉症発症者と感作未発症者における特異的T細胞の差異の探索2019
- Author(s)
  飯沼智久
- Organizer
  日本耳鼻咽喉科免疫アレルギー学会
- Data Source
  KAKENHI-PROJECT-18K16874
[Presentation] Pathogenic Th2 cells develop the symptoms of allergic rhinitis2019
- Author(s)
  Tomohisa Iinuma
- Organizer
  2019 KAAACI-KAPARD-WPAS-INTERASMA Joint Congress
- Invited / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-18K16874
[Presentation] Effect of AIT: clinical and basic research2019
- Author(s)
  Tomohisa Iinuma
- Organizer
  DGAKI-JSA Joint Meeting
- Invited / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-18K16874
[Presentation] The pathogenicity of memory Th2 cell is involved in the onset of allergic rhinitis and changed by immunotherapy2018
- Author(s)
  Tomohisa Iinuma
- Organizer
  The Joint Congress of the Asia Pacific Association of Allergy, Asthma and Clinical Immunology & the Asia Pacific Association of Pediatric Allergy, Respirology and Immunology
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-18K16874
[Presentation] スギ花粉症の発症に関わるPathogenic Th2細胞の検討2016
- Author(s)
  飯沼智久、米倉修二、新井智之、國井直樹、櫻井大樹、岡本美孝
- Organizer
  日本耳鼻咽喉科免疫アレルギー学会
- Place of Presentation
  鳥羽国際ホテル（三重県・鳥羽市）
- Year and Date
  2016-02-04
- Data Source
  KAKENHI-PROJECT-15K20183
[Presentation] Pathogenicity of memory Th2 cell changes and is linked to stage of allergic rhinitis2015
- Author(s)
  Tomohisa Iinuma、Yoshitaka Okamoto
- Organizer
  13th Japan-Taiwan Conference on Otolaryngology-Head and Neck Surgery
- Place of Presentation
  一橋大学一橋講堂（東京都・千代田区）
- Year and Date
  2015-12-03
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-15K20183
[Presentation] アレルギー性鼻炎の病態機序に基づいた新たな治療戦略2015
- Author(s)
  飯沼智久
- Organizer
  日本鼻科学会
- Place of Presentation
  広島国際会議場（広島県・広島市）
- Year and Date
  2015-10-01
- Invited
- Data Source
  KAKENHI-PROJECT-15K20183

1. 平原潔 (00707193)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
2. 栗田惇也 (80867268)

# of Collaborated Projects: 1 results

# of Collaborated Products: 6 results
3. FUKUYO Masaki

# of Collaborated Projects: 0 results

# of Collaborated Products: 1 results
4. 木内政宏

# of Collaborated Projects: 0 results

# of Collaborated Products: 1 results

IINUMA TOMOHISA 飯沼 智久

Iinuma Tomohisa 飯沼 智久

飯沼 智久 イイヌマ トモヒサ

Research Projects

Research Products

Co-Researchers

Unraveling the Mechanism of Action of Sublingual Immunotherapy Using Single-Cell AnalysisPrincipal Investigator

Principal Investigator

Project Period (FY)

Research Category

Review Section

Research Institution

Investigation of the onset of Japanese cedar pollen induced allergic rhinitis from the point of the Asymptomatic sensitization stage and the T cell functionPrincipal Investigator

Principal Investigator

Project Period (FY)

Research Category

Review Section

Research Institution

スギ花粉症の感作・発症因子とPathogenic T細胞の機能との関連Principal Investigator

Principal Investigator

Project Period (FY)

Research Category

Research Field

Research Institution

[Journal Article] Adherence to Treatment in Allergic Rhinitis During the Pollen Season in Europe: A MASK‐air Study2025

Author(s)

Journal Title

DOI

Data Source

[Journal Article] Concepts for the Development of Person-Centered, Digitally Enabled, Artificial Intelligence?Assisted ARIA Care Pathways (ARIA 2024)2024

Author(s)

Journal Title

DOI

Data Source

[Journal Article] A case of IgG4-related disease with laryngeal lesions that was difficult to diagnose2024

Author(s)

Journal Title

DOI

ISSN

Language

Data Source

[Journal Article] Factors contributing to the diagnosis and onset prediction of perennial allergic rhinitis in high-risk children: A sub-analysis of the CHIBA study2024

Author(s)

Journal Title

DOI

ISSN

Language

Data Source

[Journal Article] Perceptions of the impact of individual allergic rhinitis symptoms: A survey of ARIA clinical experts2024

Author(s)

Journal Title

DOI

Data Source

[Journal Article] Differences in the expression of multidrug resistance proteins in chronic rhinosinusitis according to endotype2023

Author(s)

Journal Title

DOI

ISSN

Language

Data Source

[Journal Article] Pathogenic helper T cells as the novel therapeutic targets for immune-mediated intractable diseases2023

Author(s)

Journal Title

DOI

Data Source

[Journal Article] Single-cell immunoprofiling after immunotherapy for allergic rhinitis reveals functional suppression of pathogenic TH2 cells and clonal conversion2022

Author(s)

Journal Title

DOI

Data Source

[Journal Article] Complement Factor H Is an Early Predictive Biomarker of the Therapeutic Efficacy of Sublingual Immunotherapy for Japanese Cedar Pollinosis2022

Author(s)

Journal Title

DOI

Data Source

[Presentation] スマートフォンアプリMASK-airからみる年間の鼻アレルギー症状変化と関連2024

Author(s)

Organizer

Data Source

[Presentation] デジタル技術を利用したアレルギー診療と研究2024

IINUMA TOMOHISA 飯沼智久

Iinuma Tomohisa 飯沼智久

飯沼智久イイヌマトモヒサ