Ogasawara Yuta 小笠原裕太

Researcher Number	00773524
Other IDs
Affiliation (Current)	2026: 公益財団法人微生物化学研究会, 微生物化学研究所, 博士研究員 2026: 北海道大学, 遺伝子病制御研究所, 特任助教
Affiliation (based on the past Project Information) *help	2022 – 2024: 北海道大学, 遺伝子病制御研究所, 特任助教 2021: 公益財団法人微生物化学研究会, 微生物化学研究所, 博士研究員 2019 – 2020: 順天堂大学, 医学(系)研究科(研究院), 博士研究員 2017 – 2018: 名古屋大学, 医学系研究科, 特任助教
Review Section/Research Field	Principal Investigator Basic Section 44010:Cell biology-related / Basic Section 48010:Anatomy-related / General anatomy (including histology/embryology)
Keywords	Principal Investigator オートファジー / 脂質代謝 / 膜脂質 / ホスファチジルコリン / phosphatidylcholine / 液-液相分離 / 核膜 / 核膜ストレス / 膜脂質供給機構 / CCT beta 3 … More / 隔離膜 / kennedy pathway / 脂肪滴 / Click chemistry / Lipid droplet / Lipid metabolism / Autophagy / 膜供給機構 / CCTbeta3 / CCTβ3 / Kennedy pathway / lipid droplet Less

隔離膜-ERコンタクト部位に形成されるAtg液滴様構造体および濃縮ERの制御機構解明Principal Investigator
- Principal Investigator
  
  小笠原裕太
- Project Period (FY)
  2024 – 2026
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Review Section
  
  Basic Section 44010:Cell biology-related
- Research Institution
  Hokkaido University
Analysis of nuclear membrane stress production mechanism associated with the regulation of nuclear membrane lipid metabolismPrincipal Investigator
- Principal Investigator
  
  Ogasawara Yuta
- Project Period (FY)
  2021 – 2023
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Review Section
  
  Basic Section 44010:Cell biology-related
- Research Institution
  Hokkaido University
  Microbial Chemistry Research Foundation
長時間にわたって継続するオートファジーを維持する機構の解析Principal Investigator
- Principal Investigator
  
  小笠原裕太
- Project Period (FY)
  2019 – 2020
- Research Category
  
  Grant-in-Aid for Early-Career Scientists
- Review Section
  
  Basic Section 48010:Anatomy-related
- Research Institution
  Juntendo University
Analysis of the mechanism of phospholipid supply on autophagosomal membrane formationPrincipal Investigator
- Principal Investigator
  
  Ogasawara Yuta
- Project Period (FY)
  2017 – 2018
- Research Category
  
  Grant-in-Aid for Young Scientists (B)
- Research Field
  
  General anatomy (including histology/embryology)
- Research Institution
  Nagoya University

All 2024 2023 2022 2021 2020 2019 2018 2017

All Journal Article Presentation Book

[Book] 医学のあゆみオートファジーと脂肪滴の関わり2020
- Author(s)
  小笠原裕太, 辻　琢磨, 藤本豊士
- Total Pages
  6
- Publisher
  医歯薬出版株式会社
- ISBN
  4910204750204
- Data Source
  KAKENHI-PROJECT-19K16474
[Journal Article] Autophagy and cancer: basic mechanisms and inhibitor development2023
- Author(s)
  Hama Yutaro、Ogasawara Yuta、Noda Nobuo N.
- Journal Title
  
  Cancer Science
  
  Volume: - Issue: 7 Pages: 2699-2708
- DOI
  10.1111/cas.15803
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-21K06173, KAKENHI-PROJECT-23K14140, KAKENHI-PROJECT-22KJ0044, KAKENHI-PLANNED-19H05707
[Journal Article] The mitochondrial intermembrane space protein mitofissin drives mitochondrial fission required for mitophagy2023
- Author(s)
  Fukuda Tomoyuki, Furukawa Kentaro, Maruyama Tatsuro, ..., Klionsky J. Daniel, Noda N. Nobuo, Kanki Tomotake.
- Journal Title
  
  Molecular Cell
  
  Volume: - Issue: 12 Pages: 2045-2058.e9
- DOI
  10.1016/j.molcel.2023.04.022
- Peer Reviewed / Open Access / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-21K15045, KAKENHI-PROJECT-23K05679, KAKENHI-PROJECT-21K05500, KAKENHI-PROJECT-21K06173, KAKENHI-PLANNED-19H05707, KAKENHI-PLANNED-19H05712, KAKENHI-PROJECT-22H04926, KAKENHI-PROJECT-23K23878, KAKENHI-PUBLICLY-23H04255
[Journal Article] Targeting the ATG5-ATG16L1 Protein-Protein Interaction with a Hydrocarbon-Stapled Peptide Derived from ATG16L1 for Autophagy Inhibition2022
- Author(s)
  Cui Jin、Ogasawara Yuta、Kurata Ikuko、Matoba Kazuaki、Fujioka Yuko、Noda Nobuo N.、Shibasaki Masakatsu、Watanabe Takumi
- Journal Title
  
  Journal of the American Chemical Society
  
  Volume: 144 Issue: 38 Pages: 17671-17679
- DOI
  10.1021/jacs.2c07648
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-21K06173, KAKENHI-PUBLICLY-21H05731, KAKENHI-PROJECT-20K06567, KAKENHI-PLANNED-19H05707, KAKENHI-PROJECT-21K06055
[Journal Article] Multifarious roles of lipid droplets in autophagy ? Target, product, and what else?2020
- Author(s)
  Ogasawara Yuta、Tsuji Takuma、Fujimoto Toyoshi
- Journal Title
  
  Seminars in Cell & Developmental Biology
  
  Volume: － Pages: 47-54
- DOI
  10.1016/j.semcdb.2020.02.013
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-19K16474, KAKENHI-PROJECT-19K07265, KAKENHI-PUBLICLY-20H05339, KAKENHI-PROJECT-18H04023
[Journal Article] Long-term autophagy is sustained by activation of CCTβ3 on lipid droplets2020
- Author(s)
  Ogasawara Yuta、Cheng Jinglei、Tatematsu Tsuyako、Uchida Misaki、Murase Omi、Yoshikawa Shogo、Ohsaki Yuki、Fujimoto Toyoshi
- Journal Title
  
  Nature Communications
  
  Volume: 11 Issue: 1 Pages: 4480-4480
- DOI
  10.1038/s41467-020-18153-w
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-18H04023, KAKENHI-PROJECT-18K06829, KAKENHI-PROJECT-19K16474
[Presentation] 液-液相分離を伴う哺乳類オートファジー新規制御機構の解析2024
- Author(s)
  小笠原裕太、辻琢磨、CALDWELL ELIJAH、濱祐太郎、的場一晃、藤岡優子、野田展生
- Organizer
  第16 回オートファジー研究会/第1 回国際先導研究リトリート
- Data Source
  KAKENHI-PROJECT-24K09431
[Presentation] 液-液相分離を介した哺乳類オートファジー制御機構の解析2024
- Author(s)
  小笠原裕太、CALDWELL ELIJAH、辻琢磨、濱祐太郎、的場一晃、藤岡優子、野田展生
- Organizer
  第47回日本分子生物学会年会,
- Data Source
  KAKENHI-PROJECT-24K09431
[Presentation] 小胞体-隔離膜コンタクト部位において形成される哺乳類Atgを伴った液滴様構造の機能解析2024
- Author(s)
  小笠原裕太、濱祐太郎、的場一、辻琢磨、野田展生
- Organizer
  第24回日本蛋白質科学会年会
- Data Source
  KAKENHI-PROJECT-24K09431
[Presentation] Functional analysis of droplet-like structures regulating mammalian autophagy.2024
- Author(s)
  Ogasawara Yuta, Hama Yutaro, Matoba Kazuaki, Tsuji Takuma and Noda Nobuo
- Organizer
  第19回生命医科学研究所ネットワーク国際シンポジウム
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-24K09431
[Presentation] 小胞体－隔離膜形成部位における小胞体濃縮機構の解析2023
- Author(s)
  小笠原裕太、濱祐太郎、的場一晃、辻琢磨、野田展生
- Organizer
  第15回オートファジー研究会・若手の会・新学術領域「マルチモードオートファジー」第5回班会議
- Data Source
  KAKENHI-PROJECT-21K06173
[Presentation] 哺乳類オートファジーにおける小胞体-隔離膜コンタクトサイトの解析2022
- Author(s)
  Yuta Ogasawara, Kazuaki Matoba, Yutaro Hama, Nobuo Noda.
- Organizer
  第59回日本生化学会北海道支部例会日本生化学会北海道支部・日本生物物理学会北海道支部合同シンポジウム
- Invited
- Data Source
  KAKENHI-PROJECT-21K06173
[Presentation] 長期的な飢餓条件下におけるオートファジー維持機構2021
- Author(s)
  小笠原裕太、程晶磊、立松律弥子、内田岬希、村瀬桜波、吉川翔吾、大崎雄樹、藤本豊士
- Organizer
  「マルチモードオートファジー」第３回班会議　第１４回オートファジー研究会・若手の会
- Data Source
  KAKENHI-PROJECT-21K06173
[Presentation] 長時間飢餓時のオートファジーにおけるホスファチジルコリン供給機構2020
- Author(s)
  小笠原裕太、程晶磊、立松律弥子、内田岬希、村瀬桜波、吉川尚吾、大崎雄樹、藤本豊士
- Organizer
  第93回日本生化学会大会
- Invited
- Data Source
  KAKENHI-PROJECT-19K16474
[Presentation] 長時間飢餓時のオートファジーにおける膜脂質供給機構2019
- Author(s)
  小笠原裕太, 内田岬, 杉本拓也, 村瀬桜波, 藤本豊士
- Organizer
  第124回日本解剖学会総会全国学術集会
- Data Source
  KAKENHI-PROJECT-17K15545
[Presentation] 長期に持続するオートファジーと膜脂質合成2019
- Author(s)
  Ogasawara Y, Uchida M, Momota K, Murase O, Yoshikawa S, Cheng J, Fujimoto T.
- Organizer
  第60回日本組織細胞化学会総会・学術集会
- Invited
- Data Source
  KAKENHI-PROJECT-19K16474
[Presentation] 長時間飢餓時のオートファジーにおける膜脂質供給機構2018
- Author(s)
  Ogasawara Y, Fujimoto T.
- Organizer
  第11回オートファジー研究会
- Data Source
  KAKENHI-PROJECT-17K15545
[Presentation] De novo synthesis of phosphatidylcholine and autophagic membrane formation2018
- Author(s)
  Ogasawara Y, Sugimoto T, Uchida M, Murase O, Fujimoto T
- Organizer
  Joint Annual Meeting of 51st JSDB and 70th JSCB
- Data Source
  KAKENHI-PROJECT-17K15545
[Presentation] オートファジーにおけるホスファチジルコリン (PC) 供給機構の解析2018
- Author(s)
  Ogasawara Y, Sugimoto T, Uchida M, Murase O, Fujimoto T.
- Organizer
  第123回日本解剖学会総会全国学術集会
- Invited
- Data Source
  KAKENHI-PROJECT-17K15545
[Presentation] オートファゴソームへの膜脂質供給機構の解析2017
- Author(s)
  Ogasawara Y, Sugimoto T, Uchida M, Fujimoto T.
- Organizer
  2017年度生命科学系学会合同年次大会
- Invited
- Data Source
  KAKENHI-PROJECT-17K15545

1. 藤本豊士

# of Collaborated Projects: 0 results

# of Collaborated Products: 1 results
2. 大崎雄樹

# of Collaborated Projects: 0 results

# of Collaborated Products: 1 results
3. 丸山達朗

# of Collaborated Projects: 0 results

# of Collaborated Products: 1 results

Ogasawara Yuta 小笠原 裕太

Research Projects

Research Products

Co-Researchers

隔離膜-ERコンタクト部位に形成されるAtg液滴様構造体および濃縮ERの制御機構解明Principal Investigator

Principal Investigator

Project Period (FY)

Research Category

Review Section

Research Institution

Analysis of nuclear membrane stress production mechanism associated with the regulation of nuclear membrane lipid metabolismPrincipal Investigator

Principal Investigator

Project Period (FY)

Research Category

Review Section

Research Institution

長時間にわたって継続するオートファジーを維持する機構の解析Principal Investigator

Principal Investigator

Project Period (FY)

Research Category

Review Section

Research Institution

Analysis of the mechanism of phospholipid supply on autophagosomal membrane formationPrincipal Investigator

Principal Investigator

Project Period (FY)

Research Category

Research Field

Research Institution

[Book] 医学のあゆみ オートファジーと脂肪滴の関わり2020

Author(s)

Total Pages

Publisher

ISBN

Data Source

[Journal Article] Autophagy and cancer: basic mechanisms and inhibitor development2023

Author(s)

Journal Title

DOI

Data Source

[Journal Article] The mitochondrial intermembrane space protein mitofissin drives mitochondrial fission required for mitophagy2023

Author(s)

Journal Title

DOI

Data Source

[Journal Article] Targeting the ATG5-ATG16L1 Protein-Protein Interaction with a Hydrocarbon-Stapled Peptide Derived from ATG16L1 for Autophagy Inhibition2022

Author(s)

Journal Title

DOI

Data Source

[Journal Article] Multifarious roles of lipid droplets in autophagy ? Target, product, and what else?2020

Author(s)

Journal Title

DOI

Data Source

[Journal Article] Long-term autophagy is sustained by activation of CCTβ3 on lipid droplets2020

Author(s)

Journal Title

DOI

Data Source

[Presentation] 液-液相分離を伴う哺乳類オートファジー新規制御機構の解析2024

Author(s)

Organizer

Data Source

[Presentation] 液-液相分離を介した哺乳類オートファジー制御機構の解析2024

Author(s)

Organizer

Data Source

[Presentation] 小胞体-隔離膜コンタクト部位において形成される哺乳類Atgを伴った液滴様構造の機能解析2024

Author(s)

Organizer

Data Source

[Presentation] Functional analysis of droplet-like structures regulating mammalian autophagy.2024

Author(s)

Organizer

Data Source

[Presentation] 小胞体－隔離膜形成部位における小胞体濃縮機構の解析2023

Author(s)

Organizer

Data Source

[Presentation] 哺乳類オートファジーにおける小胞体-隔離膜コンタクトサイトの解析2022

Ogasawara Yuta 小笠原裕太

[Book] 医学のあゆみオートファジーと脂肪滴の関わり2020