Shimizu Masahiro 清水幹容

Researcher Number	00774358
Other IDs
Affiliation (Current)	2025: 東京科学大学, 総合研究院, 助教
Affiliation (based on the past Project Information) *help	2024: 東京医科歯科大学, 難治疾患研究所, 助教 2019 – 2022: 東京医科歯科大学, 難治疾患研究所, 助教 2017 – 2019: 日本医科大学, 大学院医学研究科, ポストドクター
Review Section/Research Field	Principal Investigator Basic Section 50010:Tumor biology-related Except Principal Investigator Pathological medical chemistry
Keywords	Principal Investigator O-GlcNAc / がん幹細胞 / エピゲノム / クロマチン領域 / Cancer stem cells / IL-8 / cancer stem cells / O-GlcNAc修飾 / SOX2 / RAS / CSC … More Except Principal Investigator … More Sox2 / がん化学療法 / がんの再発 / グルコース代謝 / O-GlcNAc修飾 / STAT3 / がんの再発防止 / がん微小環境 / 肺がん / OCT4 / SOX2 / リプログラミング / p53 / 薬剤スクリーニング / PRMT5 / MEP50 / GLI1 / O-GlcNAcylation / IL-8 / がん治療 / がん幹細胞 Less

O-GlcNAc修飾により制御されるがん幹細胞クロマチン領域と制御機構の解明Principal Investigator
- Principal Investigator
  
  清水幹容
- Project Period (FY)
  2024 – 2026
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Review Section
  
  Basic Section 50010:Tumor biology-related
- Research Institution
  Tokyo Medical and Dental University
Mechanism of IL-8 dependent regulation of cancer stem cells.Principal Investigator
- Principal Investigator
  
  Shimizu Masahiro
- Project Period (FY)
  2019 – 2022
- Research Category
  
  Grant-in-Aid for Early-Career Scientists
- Review Section
  
  Basic Section 50010:Tumor biology-related
- Research Institution
  Tokyo Medical and Dental University
Generation and maintenance mechanism of cancer stem cells in tumor microenvironment, involved in lung cancer development and reocurrence.
- Principal Investigator
  
  Tanaka Nobuyuki
- Project Period (FY)
  2017 – 2019
- Research Category
  
  Grant-in-Aid for Scientific Research (B)
- Research Field
  
  Pathological medical chemistry
- Research Institution
  Nippon Medical School

All 2022 2021 2020 2019 2018 2017

All Journal Article Presentation

[Journal Article] Enhanced O-GlcNAc modification induced by the RAS/MAPK/CDK1 pathway is required for SOX2 protein expression and generation of cancer stem cells2022
- Author(s)
  Shimizu Masahiro、Shibuya Hiroshi、Tanaka Nobuyuki
- Journal Title
  
  Scientific Reports
  
  Volume: 12 Issue: 1 Pages: 2910-2910
- DOI
  10.1038/s41598-022-06916-y
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-21K06165, KAKENHI-PROJECT-19K16782
[Journal Article] WNK1/HSN2 mediates neurite outgrowth and differentiation via a OSR1/GSK3β-LHX8 pathway2022
- Author(s)
  Shimizu Masahiro、Shibuya Hiroshi
- Journal Title
  
  Scientific Reports
  
  Volume: 12 Issue: 1 Pages: 15858-15858
- DOI
  10.1038/s41598-022-20271-y
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-21K06165, KAKENHI-PROJECT-19K16782
[Journal Article] WNK regulates Wnt signalling and β-Catenin levels by interfering with the interaction between β-Catenin and GID2020
- Author(s)
  Sato Atsushi、Shimizu Masahiro、Goto Toshiyasu、Masuno Hiroyuki、Kagechika Hiroyuki、Tanaka Nobuyuki、Shibuya Hiroshi
- Journal Title
  
  Communications Biology
  
  Volume: 3 Issue: 1 Pages: 666-666
- DOI
  10.1038/s42003-020-01386-2
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-19K16782, KAKENHI-PROJECT-18K06208
[Journal Article] IL-8-induced O-GlcNAc modification via GLUT3 and GFAT regulates cancer stem cell-like properties in colon and lung cancer cells2018
- Author(s)
  Shimizu Masahiro、Tanaka Nobuyuki
- Journal Title
  
  Oncogene
  
  Volume: 38 Issue: 9 Pages: 1520-1533
- DOI
  10.1038/s41388-018-0533-4
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-17H04054, KAKENHI-PROJECT-19K16782
[Presentation] CXCR2依存的ながん幹細胞集団の解析2021
- Author(s)
  清水幹容, 澁谷浩司, 田中信之
- Organizer
  第44回日本分子生物学会
- Data Source
  KAKENHI-PROJECT-19K16782
[Presentation] IL-8依存的ながん幹細胞の制御機構の解析2020
- Author(s)
  清水幹容、田中信之、澁谷浩司
- Organizer
  第43回日本分子生物学会
- Data Source
  KAKENHI-PROJECT-19K16782
[Presentation] IL-8はGLUT3とGFATを介してO-GlcNAc修飾を誘導し、癌幹細胞能を制御する2019
- Author(s)
  清水幹容, 田中信之
- Organizer
  第42回　日本分子生物学会年会
- Data Source
  KAKENHI-PROJECT-17H04054
[Presentation] IL-8はGLUT3とGFATを介してO-GlcNAc修飾を誘導し、癌幹細胞能を制御する2019
- Author(s)
  清水幹容、田中信之
- Organizer
  日本分子生物学会
- Data Source
  KAKENHI-PROJECT-19K16782
[Presentation] IL-8 supports development of cancer stem cells via glucose metabolism.2017
- Author(s)
  清水幹容、田中信之
- Organizer
  第40回日本分子生物学会年会
- Data Source
  KAKENHI-PROJECT-17H04054

1. Tanaka Nobuyuki (80222115)

# of Collaborated Projects: 1 results

# of Collaborated Products: 3 results
2. 弦間昭彦 (20234651)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
3. 澁谷浩司

# of Collaborated Projects: 0 results

# of Collaborated Products: 2 results

Shimizu Masahiro 清水 幹容

Research Projects

Research Products

Co-Researchers

O-GlcNAc修飾により制御されるがん幹細胞クロマチン領域と制御機構の解明Principal Investigator

Principal Investigator

Project Period (FY)

Research Category

Review Section

Research Institution

Mechanism of IL-8 dependent regulation of cancer stem cells.Principal Investigator

Principal Investigator

Project Period (FY)

Research Category

Review Section

Research Institution

Generation and maintenance mechanism of cancer stem cells in tumor microenvironment, involved in lung cancer development and reocurrence.

Principal Investigator

Project Period (FY)

Research Category

Research Field

Research Institution

[Journal Article] Enhanced O-GlcNAc modification induced by the RAS/MAPK/CDK1 pathway is required for SOX2 protein expression and generation of cancer stem cells2022

Author(s)

Journal Title

DOI

Data Source

[Journal Article] WNK1/HSN2 mediates neurite outgrowth and differentiation via a OSR1/GSK3β-LHX8 pathway2022

Author(s)

Journal Title

DOI

Data Source

[Journal Article] WNK regulates Wnt signalling and β-Catenin levels by interfering with the interaction between β-Catenin and GID2020

Author(s)

Journal Title

DOI

Data Source

[Journal Article] IL-8-induced O-GlcNAc modification via GLUT3 and GFAT regulates cancer stem cell-like properties in colon and lung cancer cells2018

Author(s)

Journal Title

DOI

Data Source

[Presentation] CXCR2依存的ながん幹細胞集団の解析2021

Author(s)

Organizer

Data Source

[Presentation] IL-8依存的ながん幹細胞の制御機構の解析2020

Author(s)

Organizer

Data Source

[Presentation] IL-8はGLUT3とGFATを介してO-GlcNAc修飾を誘導し、癌幹細胞能を制御する2019

Author(s)

Organizer

Data Source

[Presentation] IL-8はGLUT3とGFATを介してO-GlcNAc修飾を誘導し、癌幹細胞能を制御する2019

Author(s)

Organizer

Data Source

[Presentation] IL-8 supports development of cancer stem cells via glucose metabolism.2017

Author(s)

Organizer

Data Source

Shimizu Masahiro 清水幹容