Hiono takahiro 日尾野隆大

… Alternative Names

Hiono Takahiro 日尾野隆大

Less

Researcher Number	00775819
Other IDs
Affiliation (Current)	2025: 北海道大学, One Healthリサーチセンター, 准教授
Affiliation (based on the past Project Information) *help	2023 – 2024: 北海道大学, One Healthリサーチセンター, 講師 2020 – 2023: 北海道大学, 獣医学研究院, 講師 2017 – 2019: 国立研究開発法人産業技術総合研究所, 生命工学領域, 研究員 2016: 北海道大学, 獣医学研究科, 特任助教
Review Section/Research Field	Principal Investigator Basic Section 42020:Veterinary medical science-related / Basic Section 49060:Virology-related / Veterinary medical science Except Principal Investigator Medium-sized Section 42:Veterinary medical science, animal science, and related fields
Keywords	Principal Investigator グライコフォーム / レクチンマイクロアレイ / インフルエンザウイルス / 糖タンパク質 / αGal / ウイルス糖タンパク質 / レクチンアレイ / SARS-CoV-2 / 糖鎖 / ウイルス学 … More / 糖鎖生物学 / 宿主間伝播 / インフルエンサウイルス / 糖鎖構造解析 / 免疫原性 / レクチン / ウイルス / マンノース型糖鎖 / グライコプロテオミクス / A型インフルエンザウイルス / グライコミクス / シアロ糖 / 鳥インフルエンザ … More Except Principal Investigator RNAメチルトランスフェラーゼ / RNAメチル基転移酵素 / 薬剤耐性 / 計算創薬 / 宿主因子 / RNAメチル基転移構造 / 抗ウイルス薬 / インフルエンザウイルス Less

Glycoforms of viral proteins and their immunogenicityPrincipal Investigator
- Principal Investigator
  
  日尾野隆大
- Project Period (FY)
  2024 – 2026
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Review Section
  
  Basic Section 42020:Veterinary medical science-related
- Research Institution
  Hokkaido University
宿主RNAメチルトランスフェラーゼを標的とした抗インフルエンザウイルス薬の探索
- Principal Investigator
  
  五十嵐学
- Project Period (FY)
  2022 – 2025
- Research Category
  
  Fund for the Promotion of Joint International Research (Fostering Joint International Research (B))
- Review Section
  
  Medium-sized Section 42:Veterinary medical science, animal science, and related fields
- Research Institution
  Hokkaido University
Novel biological functions of glycans attached to the viruses in interspecies transmissionPrincipal Investigator
- Principal Investigator
  
  Hiono Takahiro
- Project Period (FY)
  2021 – 2023
- Research Category
  
  Grant-in-Aid for Early-Career Scientists
- Review Section
  
  Basic Section 42020:Veterinary medical science-related
- Research Institution
  Hokkaido University
Development of a technological basis for elucidating the significance of glycosylation alterations in viral infectionPrincipal Investigator
- Principal Investigator
  
  Hiono Takahiro
- Project Period (FY)
  2018 – 2021
- Research Category
  
  Grant-in-Aid for Early-Career Scientists
- Review Section
  
  Basic Section 49060:Virology-related
- Research Institution
  Hokkaido University
  National Institute of Advanced Industrial Science and Technology
Comprehensive analyses of the interaction between host glycan and influenza viruses and its significance in virus infectionPrincipal Investigator
- Principal Investigator
  
  Hiono Takahiro
- Project Period (FY)
  2016 – 2017
- Research Category
  
  Grant-in-Aid for Research Activity Start-up
- Research Field
  
  Veterinary medical science
- Research Institution
  National Institute of Advanced Industrial Science and Technology
  Hokkaido University

All 2024 2023 2022 2021 2020 2019 2018 2017

All Journal Article Presentation

[Journal Article] Continuous Introduction of H5 High Pathogenicity Avian Influenza Viruses in Hokkaido, Japan: Characterization of Viruses Isolated in Winter 2022-2023 and Early Winter 2023-20242024
- Author(s)
  Hew Lim Yik、Isoda Norikazu、Takaya Fumihito、Ogasawara Kohei、Kobayashi Daiki、Huynh Loc Tan、Morita Tatsuru、Harada Rio、Zinyakov Nikolay Gennadievich、Andreychuk Dmitriy Borisovich、Chvala Ilya Alexandrovich、Irza Viktor Nikolaevich、Watanabe Yukiko、Fujita Hiroko、Saito Keisuke、Hiono Takahiro、Sakoda Yoshihiro
- Journal Title
  
  Transboundary and Emerging Diseases
  
  Volume: 2024 Issue: 1 Pages: 1-18
- DOI
  10.1155/2024/1199876
- Peer Reviewed / Open Access / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-23KJ0059, KAKENHI-PROJECT-21K14982
[Journal Article] Inhibition of cellular RNA methyltransferase abrogates influenza virus capping and replication2023
- Author(s)
  Tsukamoto Y, Hiono T, Matsuno K, Igarashi M, Kato H, et al.
- Journal Title
  
  Science
  
  Volume: 379 Issue: 6632 Pages: 586-591
- DOI
  10.1126/science.add0875
- Peer Reviewed / Open Access / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-22KK0094, KAKENHI-PROJECT-18KK0232
[Journal Article] Detection of H5N1 High Pathogenicity Avian Influenza Viruses in Four Raptors and Two Geese in Japan in the Fall of 20222023
- Author(s)
  Nabeshima Kei、Takadate Yoshihiro、Soda Kosuke、Hiono Takahiro、Isoda Norikazu、Sakoda Yoshihiro、Mine Junki、Miyazawa Kohtaro、Onuma Manabu、Uchida Yuko
- Journal Title
  
  Viruses
  
  Volume: 15 Issue: 9 Pages: 1865-1865
- DOI
  10.3390/v15091865
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-21K14982
[Journal Article] Turkeys possess diverse Siaα2-3Gal glycans that facilitate their dual susceptibility to avian influenza viruses isolated from ducks and chickens.2022
- Author(s)
  Kobayashi D, Hiono T, Ichii O, Nishihara S, Takase-Yoden S, Yamamoto K, Kawashima H, Isoda N, and Sakoda Y.
- Journal Title
  
  Virus Res.
  
  Volume: 315 Pages: 198771-198771
- DOI
  10.1016/j.virusres.2022.198771
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-20H03379, KAKENHI-PROJECT-21K14982
[Journal Article] Combinatorial approach with mass spectrometry and lectin microarray dissected glycoproteomic features of virion-derived spike protein of SARS-CoV-22021
- Author(s)
  Hiono Takahiro、Tomioka Azusa、Kaji Hiroyuki、Sasaki Michihito、Orba Yasuko、Sawa Hirofumi、Kuno Atsushi
- Journal Title
  
  BioRxiv
  
  Volume: なし
- DOI
  10.1101/2021.04.10.439300
- Open Access
- Data Source
  KAKENHI-PROJECT-18K15176
[Journal Article] E190V substitution of H6 hemagglutinin is one of key factors for binding to sulfated sialylated glycan receptor and infection to chickens2020
- Author(s)
  Kikutani Yuto、Okamatsu Masatoshi、Nishihara Shoko、Takase‐Yoden Sayaka、Hiono Takahiro、Vries Robert P.、McBride Ryan、Matsuno Keita、Kida Hiroshi、Sakoda Yoshihiro
- Journal Title
  
  Microbiology and Immunology
  
  Volume: 64 Issue: 4 Pages: 304-312
- DOI
  10.1111/1348-0421.12773
- NAID
  120007026927
- Peer Reviewed / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-18K15176
[Journal Article] C-Terminally tagged NA in replication-competent influenza A viruses reveals differences in glycan profiles between NA and HA2020
- Author(s)
  Hiono Takahiro、Kuno Atsushi
- Journal Title
  
  The Analyst
  
  Volume: 145 Issue: 17 Pages: 5845-5853
- DOI
  10.1039/d0an00770f
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-18K15176
[Journal Article] インフルエンザウイルスの糖質科学2019
- Author(s)
  日尾野隆大
- Journal Title
  
  BIO Clinica
  
  Volume: 34(2) Pages: 195-201
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-18K15176
[Journal Article] Lectin microarray analyses reveal host cell-specific glycan profiles of the hemagglutinins of influenza A viruses2019
- Author(s)
  Hiono Takahiro、Matsuda Atsushi、Wagatsuma Takanori、Okamatsu Masatoshi、Sakoda Yoshihiro、Kuno Atsushi
- Journal Title
  
  Virology
  
  Volume: 527 Pages: 132-140
- DOI
  10.1016/j.virol.2018.11.010
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-18K15176
[Journal Article] Characterization of Highly Pathogenic Avian Influenza Virus A(H5N6), Japan, November 2016.2017
- Author(s)
  (8)Okamatsu, M., Ozawa, M., Soda, K., Takakuwa, H., Haga, A., Hiono, T., Matsuu, A., Uchida, Y., Iwata, R., Matsuno, K., Kuwahara, M., Yabuta, T., Usui, T., Ito, H., Onuma, M., Sakoda, Y., Saito, T., Otsuki, K., Ito, T., Kida, H.
- Journal Title
  
  Emerging Infectious Diseases
  
  Volume: 23(4) Issue: 4 Pages: 691-695
- DOI
  10.3201/eid2304.161957
- NAID
  120006337764
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-16H06597, KAKENHI-PROJECT-25290082, KAKENHI-PROJECT-26850178, KAKENHI-PROJECT-15K21168
[Journal Article] Potency of an inactivated influenza vaccine prepared from A/duck/Hokkaido/162/2013 (H2N1) against a challenge with A/swine/Missouri/2124514/2006 (H2N3) in mice.2017
- Author(s)
  Suzuki M, Okamatsu M, Hiono T, Matsuno K, Sakoda Y
- Journal Title
  
  Journal of Veterinary Medical Science
  
  Volume: 79 Pages: 1815-1821
- NAID
  130006199241
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-16H06597
[Journal Article] Antigenic diversity of H5 highly pathogenic avian influenza viruses of clade 2.3.4.4 isolated in Asia.2017
- Author(s)
  (7)Ohkawara, A., Okamatsu, M., Ozawa, M., Chu, D.H., Nguyen, L.T., Hiono, T., Matsuno, K., Kida, H., Sakoda, Y.
- Journal Title
  
  Microbiology and Immunology
  
  Volume: 印刷中 Issue: 5 Pages: 149-158
- DOI
  10.1111/1348-0421.12478
- NAID
  120006466464
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-16H06597, KAKENHI-PROJECT-26850178
[Journal Article] Potency of whole virus particle and split virion vaccines using dissolving microneedle against challenges of H1N1 and H5N1 influenza viruses in mice.2017
- Author(s)
  (6)Nakatsukasa, A., Kuruma, K., Okamatsu, M., Hiono, T., Suzuki, M., Matsuno, K., Kida, H., Oyamada, T., Sakoda, Y.
- Journal Title
  
  Vaccine
  
  Volume: 35(21) Issue: 21 Pages: 2855-2861
- DOI
  10.1016/j.vaccine.2017.04.009
- NAID
  120006463558
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-16H06597
[Presentation] A型およびB型インフルエンザウイルスのキャップスナッチングの開始にキャップ構造における第一ヌクレオチドの2'-O位メチル化修飾が必須となる2023
- Author(s)
  塚本雄太, 日尾野隆大, 山田辰太郎, 松野啓太, 杉元聡子, 広川貴次, 下島昌幸, 迫田義博, Linda Brunotte , Christa Elisabeth Muller, 五十嵐学, 加藤博己
- Organizer
  第70回日本ウイルス学会学術集会
- Data Source
  KAKENHI-PROJECT-22KK0094
[Presentation] Protein folding of the influenza virus hemagglutinin affects its glycoforms2023
- Author(s)
  伴　日向子, Robert de Vries, 久野敦, 磯田典和, 迫田義博, 日尾野隆大
- Organizer
  第70回日本ウイルス学会学術集会
- Data Source
  KAKENHI-PROJECT-21K14982
[Presentation] Loss of multiple N-glycosylations on the neuraminidase stalk domain enhances the pathogenicity of an H7N7 high pathogenicity avian influenza virus to chickens2023
- Author(s)
  Daiki Kobayashi, Takahiro Hiono, Ayako Ohkawara, Takaya Ichikawa, Hinako Ban, Norikazu Isoda, Yoshihiro Sakoda
- Organizer
  第70回日本ウイルス学会学術集会
- Data Source
  KAKENHI-PROJECT-21K14982
[Presentation] H13 avian influenza viruses recognize fucosylated α2,3 sialosides that distributed on the respiratory tract of slaty-backed gulls2023
- Author(s)
  原田里桜, 日尾野隆大, 小林大樹, 伴日向子, 五十嵐学, 磯田典和, 迫田義博
- Organizer
  第70回日本ウイルス学会学術集会
- Data Source
  KAKENHI-PROJECT-21K14982
[Presentation] H13亜型鳥インフルエンザウイルスはカモメの呼吸器に分布するフコシル化α2,3シアル酸糖鎖を認識する2023
- Author(s)
  原田里桜, 日尾野隆大, 小林大樹, 伴日向子, 五十嵐学, 磯田典和, 迫田義博
- Organizer
  第166回日本獣医学会学術集会
- Data Source
  KAKENHI-PROJECT-21K14982
[Presentation] 質量分析とレクチンアレイを組み合わせた SARS-CoV-2スパイクタンパク質の高精度糖鎖構造解析2021
- Author(s)
  日尾野隆大、富岡あづさ、梶裕之、佐々木道仁、大場靖子、澤洋文、久野敦
- Organizer
  第164回日本獣医学会学術集会
- Data Source
  KAKENHI-PROJECT-18K15176
[Presentation] Glycoscientific approaches toward understanding the host preference of avian influenza viruses2021
- Author(s)
  Takahiro Hiono, Daiki Kobayashi, Yuto Kikutani, Masatoshi Okamatsu, Manabu Igarashi, Norikazu Isoda, Yoshihiro Sakoda, Hiroshi Kida
- Organizer
  The 6th One Health Lecture Series on Solutions to Global One Health Challenges Towards Human Animals and Environmental Health
- Invited / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-21K14982
[Presentation] Glycoscientific approaches toward understanding the host preference of avian influenza viruses2021
- Author(s)
  Takahiro Hiono
- Organizer
  The 6th One Health Lecture Series on Solutions to Global One Health Challenges Towards Human Animals and Environmental Health
- Invited / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-18K15176
[Presentation] Combinatorial approach with mass spectrometry and lectin microarray dissected glycoproteomic features of virion-derived spike protein of SARS-CoV-22021
- Author(s)
  Takahiro Hiono, Azusa Tomioka, Hiroyuki Kaji, Michihito Sasaki, Hiroaki Sakaue, Yasuko Orba, Hirofumi Sawa, Atsushi Kuno
- Organizer
  The 68th Annual Meeting of the Japanese Society for Virology
- Data Source
  KAKENHI-PROJECT-18K15176
[Presentation] 質量分析とレクチンアレイを組み合わせた SARS-CoV-2 スパイクタンパク質の高精度糖鎖構造解析2021
- Author(s)
  日尾野隆大、富岡あづさ、梶裕之、佐々木道仁、大場靖子、澤洋文、久野敦
- Organizer
  第34回インフルエンザ研究者交流の会シンポジウム
- Data Source
  KAKENHI-PROJECT-18K15176
[Presentation] A型インフルエンザウイルスのNAに付加する糖鎖の構造解析2020
- Author(s)
  日尾野隆大, 久野敦
- Organizer
  第163回日本獣医学会学術集会
- Data Source
  KAKENHI-PROJECT-18K15176
[Presentation] A型インフルエンザウイルスHAおよびNA上の糖鎖付加制御機構の解析2019
- Author(s)
  日尾野隆大、久野敦
- Organizer
  第33回インフルエンザ研究者交流の会シンポジウム
- Data Source
  KAKENHI-PROJECT-18K15176
[Presentation] レクチンマイクロアレイを用いたA型インフルエンザウイルス粒子上の糖鎖プロファイリング法の開発2018
- Author(s)
  日尾野隆大、松田厚志、我妻孝則、岡松正敏、迫田義博、久野敦
- Organizer
  第32回インフルエンザ研究者交流の会シンポジウム
- Data Source
  KAKENHI-PROJECT-18K15176
[Presentation] 鳥インフルエンザウイルスの糖鎖結合特異性2017
- Author(s)
  日尾野隆大
- Organizer
  第31回インフルエンザ研究者交流の会シンポジウム
- Invited
- Data Source
  KAKENHI-PROJECT-16H06597

1. 五十嵐学 (10374240)

# of Collaborated Projects: 1 results

# of Collaborated Products: 2 results
2. 松野啓太 (40753306)

# of Collaborated Projects: 1 results

# of Collaborated Products: 2 results
3. 小林基弘

# of Collaborated Projects: 0 results

# of Collaborated Products: 1 results
4. 川島博人

# of Collaborated Projects: 0 results

# of Collaborated Products: 1 results

Hiono takahiro 日尾野 隆大

Hiono Takahiro 日尾野 隆大

Research Projects

Research Products

Co-Researchers

Glycoforms of viral proteins and their immunogenicityPrincipal Investigator

Principal Investigator

Project Period (FY)

Research Category

Review Section

Research Institution

宿主RNAメチルトランスフェラーゼを標的とした抗インフルエンザウイルス薬の探索

Principal Investigator

Project Period (FY)

Research Category

Review Section

Research Institution

Novel biological functions of glycans attached to the viruses in interspecies transmissionPrincipal Investigator

Principal Investigator

Project Period (FY)

Research Category

Review Section

Research Institution

Development of a technological basis for elucidating the significance of glycosylation alterations in viral infectionPrincipal Investigator

Principal Investigator

Project Period (FY)

Research Category

Review Section

Research Institution

Comprehensive analyses of the interaction between host glycan and influenza viruses and its significance in virus infectionPrincipal Investigator

Principal Investigator

Project Period (FY)

Research Category

Research Field

Research Institution

[Journal Article] Continuous Introduction of H5 High Pathogenicity Avian Influenza Viruses in Hokkaido, Japan: Characterization of Viruses Isolated in Winter 2022-2023 and Early Winter 2023-20242024

Author(s)

Journal Title

DOI

Data Source

[Journal Article] Inhibition of cellular RNA methyltransferase abrogates influenza virus capping and replication2023

Author(s)

Journal Title

DOI

Data Source

[Journal Article] Detection of H5N1 High Pathogenicity Avian Influenza Viruses in Four Raptors and Two Geese in Japan in the Fall of 20222023

Author(s)

Journal Title

DOI

Data Source

[Journal Article] Turkeys possess diverse Siaα2-3Gal glycans that facilitate their dual susceptibility to avian influenza viruses isolated from ducks and chickens.2022

Author(s)

Journal Title

DOI

Data Source

[Journal Article] Combinatorial approach with mass spectrometry and lectin microarray dissected glycoproteomic features of virion-derived spike protein of SARS-CoV-22021

Author(s)

Journal Title

DOI

Data Source

[Journal Article] E190V substitution of H6 hemagglutinin is one of key factors for binding to sulfated sialylated glycan receptor and infection to chickens2020

Author(s)

Journal Title

DOI

NAID

Data Source

[Journal Article] C-Terminally tagged NA in replication-competent influenza A viruses reveals differences in glycan profiles between NA and HA2020

Author(s)

Journal Title

DOI

Data Source

[Journal Article] インフルエンザウイルスの糖質科学2019

Author(s)

Journal Title

Data Source

[Journal Article] Lectin microarray analyses reveal host cell-specific glycan profiles of the hemagglutinins of influenza A viruses2019

Author(s)

Journal Title

DOI

Data Source

Hiono takahiro 日尾野隆大

Hiono Takahiro 日尾野隆大