MATSUZAKI HIROTAKA 松崎博崇

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Matsuzaki Hirotaka 松崎博崇

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Researcher Number	00782187
Other IDs	https://orcid.org/0000-0002-8688-3005
Affiliation (Current)	2025: 東京大学, 医学部附属病院, 特任助教
Affiliation (based on the past Project Information) *help	2020 – 2025: 東京大学, 医学部附属病院, 特任助教 2018: 東京大学, 医学部附属病院, 特任助教 2017: 東京大学, 医学部附属病院, 特任臨床医
Review Section/Research Field	Principal Investigator Basic Section 53030:Respiratory medicine-related / Respiratory organ internal medicine Except Principal Investigator Basic Section 59040:Nutrition science and health science-related / Basic Section 49010:Pathological biochemistry-related
Keywords	Principal Investigator RAGE / COPD / Visium / 肥満喘息マウス / S100A8 / 肥満喘息 / asthma / 気道上皮細胞 / 気管支喘息 / NGAL … More / Ⅱ型肺胞上皮細胞 / バイオマーカー / 喘息 / ACO / 感染症 / CSE / エラスターゼ / poly(I:C) / ADAM17 / ADAM10 / COPD急性増悪 / adam17 / adam10 / exacerbation / IL-17A … More Except Principal Investigator 睡眠障害 / 頭痛 / PRS / SNP / GWAS / Polygenic risk scores / SNPs / 健康診断 / 労働生産性 / 気道上皮 / 低酸素 Less

The role of hypoxia-inducible factors in the airway epithelium in mucus-obstructive lung diseases
- Principal Investigator
  
  三上優
- Project Period (FY)
  2025 – 2027
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Review Section
  
  Basic Section 49010:Pathological biochemistry-related
- Research Institution
  The University of Tokyo
S100A8―RAGEシグナルに着目した肥満関連喘息の病態の解明Principal Investigator
- Principal Investigator
  
  松崎博崇
- Project Period (FY)
  2023 – 2025
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Review Section
  
  Basic Section 53030:Respiratory medicine-related
- Research Institution
  The University of Tokyo
Development of tailor-made health promotion system combining health examination and genomic information
- Principal Investigator
  
  Matsumoto Lumine
- Project Period (FY)
  2021 – 2024
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Review Section
  
  Basic Section 59040:Nutrition science and health science-related
- Research Institution
  The University of Tokyo
Search for new biomarkers in asthma and COPD: focus on NGAL and sRAGEPrincipal Investigator
- Principal Investigator
  
  Matsuzaki Hirotaka
- Project Period (FY)
  2020 – 2023
- Research Category
  
  Grant-in-Aid for Early-Career Scientists
- Review Section
  
  Basic Section 53030:Respiratory medicine-related
- Research Institution
  The University of Tokyo
Role of IL-17A in the development of COPD exacerbationPrincipal Investigator
- Principal Investigator
  
  MATSUZAKI HIROTAKA
- Project Period (FY)
  2017 – 2018
- Research Category
  
  Grant-in-Aid for Young Scientists (B)
- Research Field
  
  Respiratory organ internal medicine
- Research Institution
  The University of Tokyo

All 2025 2024 2022 2021 2020 2019 2018 2017

All Journal Article

[Journal Article] Short sleep duration is a significant risk factor of obesity: A multicenter observational study of healthy adults in Japan2025
- Author(s)
  Takahashi Mami、Shimamoto Takeshi、Matsumoto Lumine、Mitsui Yusuke、Masuda Yukari、Matsuzaki Hirotaka、Hasumi Eriko、Bujo Chie、Niimi Keiko、Nishikawa Takako、Wada Ryoichi、Yamamichi Nobutake
- Journal Title
  
  PLOS ONE
  
  Volume: 20 Issue: 3 Pages: e0319085-e0319085
- DOI
  10.1371/journal.pone.0319085
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-22K11255, KAKENHI-PROJECT-23K07648, KAKENHI-PROJECT-22K19665
[Journal Article] Deep generative abnormal lesion emphasization validated by nine radiologists and 1000 chest X-rays with lung nodules2024
- Author(s)
  Hanaoka Shouhei、Nomura Yukihiro、Hayashi Naoto、Sato Issei、Miki Soichiro、Yoshikawa Takeharu、Shibata Hisaichi、Nakao Takahiro、Takenaga Tomomi、Koyama Hiroaki、Cho Shinichi、Kanemaru Noriko、Fujimoto Kotaro、Sakamoto Naoya、Nishiyama Tomoya、Matsuzaki Hirotaka、Yamamichi Nobutake、Abe Osamu
- Journal Title
  
  PLOS ONE
  
  Volume: 19 Issue: 12 Pages: e0315646-e0315646
- DOI
  10.1371/journal.pone.0315646
- Data Source
  KAKENHI-PROJECT-23K07648
[Journal Article] Anti-Inflammatory Effects of Japanese Herbal Medicine Hochuekkito in a Mouse Model of Acute Exacerbation of Chronic Obstructive Pulmonary Disease2024
- Author(s)
  Fukuda Kensuke、Matsuzaki Hirotaka、Hiraishi Yoshihisa、Miyashita Naoya、Ishii Takashi、Yuki Masaaki、Isago Hideaki、Tamiya Hiroyuki、Mitani Akihisa、Saito Akira、Jo Taisuke、Nagase Takahide
- Journal Title
  
  Pharmacology
  
  Volume: 109 Issue: 2 Pages: 121-126
- DOI
  10.1159/000536348
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-22K08277, KAKENHI-PROJECT-23K07648, KAKENHI-PROJECT-18K15946, KAKENHI-PROJECT-20K17176
[Journal Article] A Japanese herbal medicine (kampo), hochuekkito (TJ-41), has anti-inflammatory effects on the chronic obstructive pulmonary disease mouse model2024
- Author(s)
  Yuki Masaaki、Ishimori Taro、Kono Shiho、Nagoshi Saki、Saito Minako、Isago Hideaki、Tamiya Hiroyuki、Fukuda Kensuke、Miyashita Naoya、Ishii Takashi、Matsuzaki Hirotaka、Hiraishi Yoshihisa、Saito Akira、Jo Taisuke、Nagase Takahide、Mitani Akihisa
- Journal Title
  
  Scientific Reports
  
  Volume: 14 Issue: 1
- DOI
  10.1038/s41598-024-60646-x
- Data Source
  KAKENHI-PROJECT-23K07648
[Journal Article] Prevalence and characteristics of minimal pleural fluid on screening chest MRI2024
- Author(s)
  Fukuda Kensuke、Matsuzaki Hirotaka、Kawahara Takuya、Yamaguchi Toshihiro、Saito Akira、Yamamichi Nobutake、Kage Hidenori、Yoshikawa Takeharu
- Journal Title
  
  Respiratory Investigation
  
  Volume: 62 Issue: 6 Pages: 1109-1116
- DOI
  10.1016/j.resinv.2024.09.014
- Data Source
  KAKENHI-PROJECT-23K07648
[Journal Article] Endoscopic reflux esophagitis and decline in pulmonary function in nonsmokers: A retrospective cohort study2024
- Author(s)
  Enokido Takayoshi、Hiraishi Yoshihisa、Jo Taisuke、Urushiyama Hirokazu、Saito Akira、Noguchi Satoshi、Hosoki Keisuke、Ishii Takashi、Miyashita Naoya、Fukuda Kensuke、Matsuki Rei、Minatsuki Chihiro、Shimamoto Takeshi、Kage Hidenori、Yamamichi Nobutake、Matsuzaki Hirotaka
- Journal Title
  
  Respiratory Investigation
  
  Volume: 62 Issue: 4 Pages: 599-605
- DOI
  10.1016/j.resinv.2024.04.017
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-23K07648, KAKENHI-PROJECT-21K08200
[Journal Article] Detection of pulmonary nodules in chest radiographs: novel cost function for effective network training with purely synthesized datasets2024
- Author(s)
  Hanaoka Shouhei、Nomura Yukihiro、Yoshikawa Takeharu、Nakao Takahiro、Takenaga Tomomi、Matsuzaki Hirotaka、Yamamichi Nobutake、Abe Osamu
- Journal Title
  
  International Journal of Computer Assisted Radiology and Surgery
  
  Volume: 19 Issue: 10 Pages: 1991-2000
- DOI
  10.1007/s11548-024-03227-7
- Data Source
  KAKENHI-PROJECT-23K07648
[Journal Article] Lysophosphatidylcholine Acyltransferase 1 Deficiency Promotes Pulmonary Emphysema via Apoptosis of Alveolar Epithelial Cells2022
- Author(s)
  Tanosaki T, Mikami Y, Shindou H, Suzuki T, Hashidate-Yoshida T, Hosoki K, Kagawa S, Miyata J, Kabata H, Masaki K, Hamamoto R, Kage H, Miyashita N, Makita K, Matsuzaki H, Suzuki Y, Mitani A, Nagase T, Shimizu T, Fukunaga K.
- Journal Title
  
  Inflammation
  
  Volume: - Issue: 4 Pages: 1765-1779
- DOI
  10.1007/s10753-022-01659-4
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-20K17176, KAKENHI-PROJECT-19K17627
[Journal Article] The Japanese Herbal (Kampo) Medicine Hochuekkito Attenuates Lung Inflammation in Lung Emphysema2021
- Author(s)
  Isago H, Mitani A, Kohno S, Nagoshi S, Ishimori T, Saito M, Tamiya H, Miyashita N, Ishii T, Matsuzaki H, Yatomi Y, Nagase T, Jo T.
- Journal Title
  
  Biological and Pharmaceutical Bulletin
  
  Volume: 44 Issue: 1 Pages: 39-45
- DOI
  10.1248/bpb.b20-00556
- NAID
  130007965315
- ISSN
  0918-6158, 1347-5215
- Year and Date
  2021-01-01
- Language
  English
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-20K17176
[Journal Article] ASCL1 promotes tumor progression through cell-autonomous signaling and immune modulation in a subset of lung adenocarcinoma2020
- Author(s)
  Miyashita N, Horie M, Mikami Y, Urushiyama H, Fukuda K, Miyakawa K, Matsuzaki H, Makita K, Morishita Y, Harada H, Backman M, Lindskog C, Brunnstr;m H, Micke P, Nagase T, Saito A.
- Journal Title
  
  Cancer Lett
  
  Volume: 489 Pages: 121-132
- DOI
  10.1016/j.canlet.2020.06.002
- Peer Reviewed / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-20K17176, KAKENHI-PROJECT-18K08170, KAKENHI-PROJECT-19K23981
[Journal Article] Atypical Type A Thymoma Variant Manifesting Polymyalgia Rheumatica2020
- Author(s)
  Yanagiya M, Hamaya H, Matsuzaki H, Ikemura M, Nakajima J.
- Journal Title
  
  Ann Thorac Surg
  
  Volume: 110 Issue: 4 Pages: e253-e255
- DOI
  10.1016/j.athoracsur.2020.02.004
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-20K17176
[Journal Article] A mouse model of asthma‐chronic obstructive pulmonary disease overlap induced by intratracheal papain2020
- Author(s)
  Fukuda Kensuke、Matsuzaki Hirotaka、Mikami Yu、Makita Kosuke、Miyakawa Kazuko、Miyashita Naoya、Hosoki Keisuke、Ishii Takashi、Noguchi Satoshi、Urushiyama Hirokazu、Horie Masafumi、Mitani Akihisa、Yamauchi Yasuhiro、Shimura Eri、Nakae Susumu、Saito Akira、Nagase Takahide、Hiraishi Yoshihisa
- Journal Title
  
  Allergy
  
  Volume: 76 Issue: 1 Pages: 390-394
- DOI
  10.1111/all.14528
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-18K15946, KAKENHI-PROJECT-20K17176, KAKENHI-PROJECT-18H02847, KAKENHI-PROJECT-18K08170
[Journal Article] CISH is a negative regulator of IL-13-induced CCL26 production in lung fibroblasts2019
- Author(s)
  Takeshima Hideyuki、Horie Masafumi、Mikami Yu、Makita Kosuke、Miyashita Naoya、Matsuzaki Hirotaka、Noguchi Satoshi、Urushiyama Hirokazu、Hiraishi Yoshihisa、Mitani Akihisa、Borok Zea、Nagase Takahide、Yamauchi Yasuhiro
- Journal Title
  
  Allergol. Int.
  
  Volume: 68 Issue: 1 Pages: 101-109
- DOI
  10.1016/j.alit.2018.08.005
- NAID
  130007557853
- ISSN
  1323-8930, 1440-1592
- Language
  English
- Peer Reviewed / Open Access / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-18K15946, KAKENHI-PROJECT-16H02653, KAKENHI-PROJECT-17K16042, KAKENHI-PROJECT-18K15945, KAKENHI-PROJECT-17K15009
[Journal Article] Naftopidil reduced the proliferation of lung fibroblasts and bleomycin-induced lung fibrosis in mice.2019
- Author(s)
  Urushiyama H, Terasaki Y, Nagasaka S, Kokuho N, Endo Y, Terasaki M, Kunugi S, Makita K, Isago H, Hosoki K, Souma K, Ishii T, Matsuzaki H, Hiraishi Y, Mikami Y, Noguchi S, Tamiya H, Mitani A, Yamauchi Y, Shimizu A, Nagase T.
- Journal Title
  
  J Cell Mol Med.
  
  Volume: 3 Issue: 5 Pages: 1-9
- DOI
  10.1111/jcmm.14255
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-17K09630, KAKENHI-PROJECT-18K15918, KAKENHI-PROJECT-17K16042, KAKENHI-PROJECT-18K15946, KAKENHI-PROJECT-19K17627, KAKENHI-PROJECT-16H02653, KAKENHI-PROJECT-17K15009
[Journal Article] Mechanism of Periostin Production in Human Bronchial Smooth Muscle Cells.2018
- Author(s)
  Makita K, Mikami Y, Matsuzaki H, Miyashita N, Takeshima H, Noguchi S, Horie M, Urushiyama H, Iikura M, Hojo M, Nagase T, Yamauchi Y.
- Journal Title
  
  Int Arch Allergy Immunol
  
  Volume: 175 Issue: 1-2 Pages: 26-35
- DOI
  10.1159/000485892
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-17K16042
[Journal Article] Integrative CAGE and DNA Methylation Profiling Identify Epigenetically Regulated Genes in NSCLC2017
- Author(s)
  Horie M, Kaczkowski B, Ohshima M, Matsuzaki H, Noguchi S, Mikami Y, Lizio M, Itoh M, Kawaji H, Lassmann T, Carninci P, Hayashizaki Y, Forrest ARR, Takai D, Yamaguchi Y, Micke P, Saito A, Nagase T.
- Journal Title
  
  Mol Cancer Res.
  
  Volume: 15 Issue: 10 Pages: 1354-1365
- DOI
  10.1158/1541-7786.mcr-17-0191
- Peer Reviewed / Open Access / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-16K11843, KAKENHI-PROJECT-17K16042, KAKENHI-PROJECT-17K18366, KAKENHI-PROJECT-16H02653

1. 福田健介 (50910759)

# of Collaborated Projects: 2 results

# of Collaborated Products: 3 results
2. 齋藤朗 (90591412)

# of Collaborated Projects: 2 results

# of Collaborated Products: 5 results
3. Matsumoto Lumine (10749873)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
4. 石井崇史 (30803118)

# of Collaborated Projects: 1 results

# of Collaborated Products: 2 results
5. 堀江真史 (60732659)

# of Collaborated Projects: 1 results

# of Collaborated Products: 1 results
6. 三上優 (50732806)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
7. 佐藤雅昭 (00623109)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
8. 山口敏弘 (50802394)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
9. 山道信毅 (30463897)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
10. 岩上将夫 (30830228)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
11. 岡田随象 (70727411)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
12. 鈴木顕 (90838806)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
13. YAMAGUCHI Yoko

# of Collaborated Projects: 0 results

# of Collaborated Products: 1 results
14. TERASAKI Mika

# of Collaborated Projects: 0 results

# of Collaborated Products: 1 results
15. 大島光宏

# of Collaborated Projects: 0 results

# of Collaborated Products: 1 results
16. MICKE Patrick

# of Collaborated Projects: 0 results

# of Collaborated Products: 1 results
17. 寺崎泰弘

# of Collaborated Projects: 0 results

# of Collaborated Products: 1 results
18. 高橋真美

# of Collaborated Projects: 0 results

# of Collaborated Products: 1 results
19. 平石尚久

# of Collaborated Projects: 0 results

# of Collaborated Products: 1 results

MATSUZAKI HIROTAKA 松崎 博崇

Matsuzaki Hirotaka 松崎 博崇

Research Projects

Research Products

Co-Researchers

The role of hypoxia-inducible factors in the airway epithelium in mucus-obstructive lung diseases

Principal Investigator

Project Period (FY)

Research Category

Review Section

Research Institution

S100A8―RAGEシグナルに着目した肥満関連喘息の病態の解明Principal Investigator

Principal Investigator

Project Period (FY)

Research Category

Review Section

Research Institution

Development of tailor-made health promotion system combining health examination and genomic information

Principal Investigator

Project Period (FY)

Research Category

Review Section

Research Institution

Search for new biomarkers in asthma and COPD: focus on NGAL and sRAGEPrincipal Investigator

Principal Investigator

Project Period (FY)

Research Category

Review Section

Research Institution

Role of IL-17A in the development of COPD exacerbationPrincipal Investigator

Principal Investigator

Project Period (FY)

Research Category

Research Field

Research Institution

[Journal Article] Short sleep duration is a significant risk factor of obesity: A multicenter observational study of healthy adults in Japan2025

Author(s)

Journal Title

DOI

Data Source

[Journal Article] Deep generative abnormal lesion emphasization validated by nine radiologists and 1000 chest X-rays with lung nodules2024

Author(s)

Journal Title

DOI

Data Source

[Journal Article] Anti-Inflammatory Effects of Japanese Herbal Medicine Hochuekkito in a Mouse Model of Acute Exacerbation of Chronic Obstructive Pulmonary Disease2024

Author(s)

Journal Title

DOI

Data Source

[Journal Article] A Japanese herbal medicine (kampo), hochuekkito (TJ-41), has anti-inflammatory effects on the chronic obstructive pulmonary disease mouse model2024

Author(s)

Journal Title

DOI

Data Source

[Journal Article] Prevalence and characteristics of minimal pleural fluid on screening chest MRI2024

Author(s)

Journal Title

DOI

Data Source

[Journal Article] Endoscopic reflux esophagitis and decline in pulmonary function in nonsmokers: A retrospective cohort study2024

Author(s)

Journal Title

DOI

Data Source

[Journal Article] Detection of pulmonary nodules in chest radiographs: novel cost function for effective network training with purely synthesized datasets2024

Author(s)

Journal Title

DOI

Data Source

[Journal Article] Lysophosphatidylcholine Acyltransferase 1 Deficiency Promotes Pulmonary Emphysema via Apoptosis of Alveolar Epithelial Cells2022

Author(s)

Journal Title

DOI

Data Source

[Journal Article] The Japanese Herbal (Kampo) Medicine Hochuekkito Attenuates Lung Inflammation in Lung Emphysema2021

Author(s)

Journal Title

DOI

NAID

MATSUZAKI HIROTAKA 松崎博崇

Matsuzaki Hirotaka 松崎博崇