MATSUMOTO SAKIKO 松本早紀子

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MATSUMOTO Sakiko 松本早紀子

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Researcher Number	00789654
Other IDs
Affiliation (Current)	2025: 名古屋大学, 医学系研究科, 講師 2025: 大阪公立大学, 大学院医学研究科, 講師
Affiliation (based on the past Project Information) *help	2025: 大阪公立大学, 大学院医学研究科, 講師 2022 – 2023: 大阪公立大学, 大学院医学研究科, 講師 2017 – 2021: 大阪市立大学, 大学院医学研究科, 助教
Review Section/Research Field	Principal Investigator Basic Section 48040:Medical biochemistry-related / General medical chemistry Except Principal Investigator General medical chemistry
Keywords	Principal Investigator 神経変性 / αシヌクレインオリゴマー / チロシンヒドロキシラーぜ / オリゴマー / DOPA化 / チロシンヒドロキシラーゼ / DOPA化αシヌクレイン / ドーパミン作動性神経 / αシヌクレイン / 微小管 … More / 海馬 / 発生・分化 / 細胞・組織 / 神経科学 / 微小管モータータンパク質 / 神経発生 … More Except Principal Investigator 滑脳症・小脳症 / 神経幹細胞の増殖 / 神経細胞の遊走 / 神経幹細胞の分裂 / microlissencephaly / α-Synuclein / 微小管ネットワーク / NuMA / 細胞質ダイニン / カタニンp80 / 中枢神経形成不全 Less

DOPA化αシヌクレインがドーパミン作動性神経の細胞死を惹起する分子機構の解明Principal Investigator
- Principal Investigator
  
  松本早紀子
- Project Period (FY)
  2025 – 2027
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Review Section
  
  Basic Section 48040:Medical biochemistry-related
- Research Institution
  Osaka Metropolitan University
新しく同定したα-シヌクレイン翻訳後修飾によるパーキンソン病発症メカニズムの解明Principal Investigator
- Principal Investigator
  
  松本早紀子
- Project Period (FY)
  2022 – 2024
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Review Section
  
  Basic Section 48040:Medical biochemistry-related
- Research Institution
  Osaka Metropolitan University
Research on the mechanism of neuronal degeneration caused by protein phosphatase 4 deficiency.Principal Investigator
- Principal Investigator
  
  Matsumoto Sakiko
- Project Period (FY)
  2019 – 2021
- Research Category
  
  Grant-in-Aid for Early-Career Scientists
- Review Section
  
  Basic Section 48040:Medical biochemistry-related
- Research Institution
  Osaka City University
Analysis of microtubule motor protein-regulatory protein NudC in nervous systemPrincipal Investigator
- Principal Investigator
  
  Matsumoto Sakiko
- Project Period (FY)
  2017 – 2018
- Research Category
  
  Grant-in-Aid for Young Scientists (B)
- Research Field
  
  General medical chemistry
- Research Institution
  Osaka City University
Clarify the pathogenic mechnism of microlissencephaly
- Principal Investigator
  
  Jin Mingyue
- Project Period (FY)
  2015 – 2017
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Research Field
  
  General medical chemistry
- Research Institution
  Osaka City University

All 2023 2022 2018 2017

All Journal Article Presentation

[Journal Article] Functional cooperation of α-synuclein and tau is essential for proper corticogenesis.2022
- Author(s)
  2.Wang S., Fu Y., Miyata T., Matsumoto S., Shinoda T., Itoh K., Harada A., Hirotsune S. and Jin M.
- Journal Title
  
  The Journal Neuroscience
  
  Volume: 42(37) Issue: 37 Pages: 7031-7046
- DOI
  10.1523/jneurosci.0396-22.2022
- Peer Reviewed / Open Access / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-21K06821, KAKENHI-PROJECT-22K06887, KAKENHI-PROJECT-22H04922, KAKENHI-PROJECT-21H02656, KAKENHI-PROJECT-22K20746, KAKENHI-PUBLICLY-21H00363, KAKENHI-PROJECT-21H02658
[Journal Article] DOPAnization of tyrosine in α-synuclein by tyrosine hydroxylase leads to the formation of oligomers.2022
- Author(s)
  1.Jin M., Matsumoto S., Ayaki T., Yamakado H., Taguchi T., Togawa N., Konno A., Hirai H., Nakajima H., Komai S., Ishida R., Chiba S., Takahashi R., Takao T. and Hirotsune S.
- Journal Title
  
  Nature Communications
  
  Volume: 13(1):6880 Issue: 1 Pages: 6880-6880
- DOI
  10.1038/s41467-022-34555-4
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-21K06821, KAKENHI-PROJECT-22K06207, KAKENHI-PROJECT-22K06887, KAKENHI-PROJECT-22H04922, KAKENHI-PROJECT-19K06899, KAKENHI-PROJECT-19K16277, KAKENHI-PROJECT-22K06454
[Journal Article] Publisher Correction: Alpha-synuclein facilitates to form short unconventional microtubules that have a unique function in the axonal transport2018
- Author(s)
  Toba Shiori、Jin Mingyue、Yamada Masami、Kumamoto Kanako、Matsumoto Sakiko、Yasunaga Takuo、Fukunaga Yuko、Miyazawa Atsuo、Fujita Sakiko、Itoh Kyoko、Fushiki Shinji、Kojima Hiroaki、Wanibuchi Hideki、Arai Yoshiyuki、Nagai Takeharu、Hirotsune Shinji
- Journal Title
  
  Scientific Reports
  
  Volume: 8 Issue: 1 Pages: 8019-8019
- DOI
  10.1038/s41598-018-25979-4
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-15K08282, KAKENHI-PROJECT-17K15603
[Journal Article] Damage-induced neuronal endopeptidase (DINE) enhances axonal regeneration potential of retinal ganglion cells after optic nerve injury.2017
- Author(s)
  Kaneko A, Kiryu-Seo S, Matsumoto S, Kiyama H
- Journal Title
  
  Cell death & disease
  
  Volume: 8巻6号e2847 Issue: 6 Pages: 1-9
- DOI
  10.1038/cddis.2017.212
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-17K15603
[Journal Article] Alpha-synuclein facilitates to form short unconventional microtubules that have a unique function in the axonal transport2017
- Author(s)
  Toba Shiori、Jin Mingyue、Yamada Masami、Kumamoto Kanako、Matsumoto Sakiko、Yasunaga Takuo、Fukunaga Yuko、Miyazawa Atsuo、Fujita Sakiko、Itoh Kyoko、Fushiki Shinji、Kojima Hiroaki、Wanibuchi Hideki、Arai Yoshiyuki、Nagai Takeharu、Hirotsune Shinji
- Journal Title
  
  Sci Rep
  
  Volume: 7 Issue: 1 Pages: 16386-16386
- DOI
  10.1038/s41598-017-15575-3
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-17K09162, KAKENHI-PROJECT-17K15603, KAKENHI-PROJECT-17H04047, KAKENHI-PROJECT-15K08283
[Presentation] パーキンソン病において形成されるDOPA化αシヌクレインの高感度検出法の確立2023
- Author(s)
  松本早紀子, 高尾敏文, 広常真治
- Organizer
  第96回日本生化学大会
- Data Source
  KAKENHI-PROJECT-22K06887
[Presentation] チロシンヒドロキシラーゼによるαシヌクレインの翻訳後修飾の同定とパーキンソン病発症メカニズムの解明2022
- Author(s)
  松本早紀子, 金明月, 綾木孝, 山門穂高, 田口智之, 十川夏子, 今野歩, 平井宏和, 高橋良輔, 高尾敏文, 広常真治
- Organizer
  第95回日本生化学大会
- Data Source
  KAKENHI-PROJECT-22K06887
[Presentation] ドーパミン作動性ニューロンに発現するチロシンヒドロキシラーゼは、αシヌクレインを翻訳後修飾してオリゴマーの形成を促進する2022
- Author(s)
  松本早紀子, 金明月, 綾木孝, 山門穂高, 田口智之, 十川夏子, 今野歩, 平井宏和, 高橋良輔, 高尾敏文, 広常真治
- Organizer
  第45回日本分子生物学会年会
- Data Source
  KAKENHI-PROJECT-22K06887
[Presentation] Alpha-synuclein has a unique function in axonal transport2017
- Author(s)
  Mingyue Jin, Shiori Toba, Sakiko Matsumoto, Shinji Hirotsune
- Organizer
  The 12th Biennial Conference of Chinese Neuroscience Society
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-15K08283

1. Jin Mingyue (60740404)

# of Collaborated Projects: 1 results

# of Collaborated Products: 4 results
2. HIROTSUNE Shinji (80337526)

# of Collaborated Projects: 1 results

# of Collaborated Products: 2 results
3. YAMADA Masami (10322851)

# of Collaborated Projects: 1 results

# of Collaborated Products: 1 results
4. YASUNAGA Takuo (60251394)

# of Collaborated Projects: 1 results

# of Collaborated Products: 1 results
5. MIYADA Takaki (70311751)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
6. OIWA Kazuhiro (10211096)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
7. FURUTA Ken'ya (40571831)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
8. TOBA Shiori (40419891)

# of Collaborated Projects: 1 results

# of Collaborated Products: 2 results
9. MIYAZAWA Atsuo

# of Collaborated Projects: 1 results

# of Collaborated Products: 1 results
10. NAGAI Kakeharu

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
11. REVERSADE Bruno

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
12. POMP Oz

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
13. Fukunaga Yuko

# of Collaborated Projects: 0 results

# of Collaborated Products: 1 results
14. Kojima Hiroaki

# of Collaborated Projects: 0 results

# of Collaborated Products: 1 results
15. Arai Yoshiyuki

# of Collaborated Projects: 0 results

# of Collaborated Products: 1 results
16. Nagai Takeharu

# of Collaborated Projects: 0 results

# of Collaborated Products: 1 results
17. 鰐渕英機

# of Collaborated Projects: 0 results

# of Collaborated Products: 1 results

MATSUMOTO SAKIKO 松本 早紀子

MATSUMOTO Sakiko 松本 早紀子

Research Projects

Research Products

Co-Researchers

DOPA化αシヌクレインがドーパミン作動性神経の細胞死を惹起する分子機構の解明Principal Investigator

Principal Investigator

Project Period (FY)

Research Category

Review Section

Research Institution

新しく同定したα-シヌクレイン翻訳後修飾によるパーキンソン病発症メカニズムの解明Principal Investigator

Principal Investigator

Project Period (FY)

Research Category

Review Section

Research Institution

Research on the mechanism of neuronal degeneration caused by protein phosphatase 4 deficiency.Principal Investigator

Principal Investigator

Project Period (FY)

Research Category

Review Section

Research Institution

Analysis of microtubule motor protein-regulatory protein NudC in nervous systemPrincipal Investigator

Principal Investigator

Project Period (FY)

Research Category

Research Field

Research Institution

Clarify the pathogenic mechnism of microlissencephaly

Principal Investigator

Project Period (FY)

Research Category

Research Field

Research Institution

[Journal Article] Functional cooperation of α-synuclein and tau is essential for proper corticogenesis.2022

Author(s)

Journal Title

DOI

Data Source

[Journal Article] DOPAnization of tyrosine in α-synuclein by tyrosine hydroxylase leads to the formation of oligomers.2022

Author(s)

Journal Title

DOI

Data Source

[Journal Article] Publisher Correction: Alpha-synuclein facilitates to form short unconventional microtubules that have a unique function in the axonal transport2018

Author(s)

Journal Title

DOI

Data Source

[Journal Article] Damage-induced neuronal endopeptidase (DINE) enhances axonal regeneration potential of retinal ganglion cells after optic nerve injury.2017

Author(s)

Journal Title

DOI

Data Source

[Journal Article] Alpha-synuclein facilitates to form short unconventional microtubules that have a unique function in the axonal transport2017

Author(s)

Journal Title

DOI

Data Source

[Presentation] パーキンソン病において形成されるDOPA化αシヌクレインの高感度検出法の確立2023

Author(s)

Organizer

Data Source

[Presentation] チロシンヒドロキシラーゼによるαシヌクレインの翻訳後修飾の同定とパーキンソン病発症メカニズムの解明2022

Author(s)

Organizer

Data Source

[Presentation] ドーパミン作動性ニューロンに発現するチロシンヒドロキシラーゼは、αシヌクレインを翻訳後修飾してオリゴマーの形成を促進する2022

Author(s)

Organizer

Data Source

[Presentation] Alpha-synuclein has a unique function in axonal transport2017

Author(s)

Organizer

Data Source

MATSUMOTO SAKIKO 松本早紀子

MATSUMOTO Sakiko 松本早紀子