Shiba Satoshi 柴知史

… Alternative Names

Satoshi Shiba 柴知史

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Researcher Number	00797003
Other IDs	https://orcid.org/0000-0001-5159-5719
Affiliation (Current)	2025: 国立研究開発法人国立がん研究センター, 研究所, 特任研究員
Affiliation (based on the past Project Information) *help	2022 – 2024: 国立研究開発法人国立がん研究センター, 研究所, 特任研究員 2018 – 2021: 国立研究開発法人国立がん研究センター, 研究所, 研究員
Review Section/Research Field	Principal Investigator Basic Section 54010:Hematology and medical oncology-related / Basic Section 53010:Gastroenterology-related Except Principal Investigator Basic Section 56030:Urology-related
Keywords	Principal Investigator 腸内細菌叢 / 腸内環境 / がん / 腸内細菌 / 免疫チェックポイント阻害剤 / 個別化医療 / 抗悪性腫瘍剤 / 抗がん剤 / 化学療法 / がん個別化医療 … More / S-1 / 大腸がん / 膵がん / メタゲノム / 腸内代謝物質 / メタボローム / マイクロバイオーム … More Except Principal Investigator メタボローム解析 / メタゲノム解析 / 腸内細菌 / 前立腺癌 / GWAS / lifestyle / metagenome analysis / short chain fatty acid / life style / polygenic risk score / metabolome analysis / lipopolysaccharide / microbiome / prostate cancer Less

Diagnostic strategy for prostate cancer based on multifaceted analyses of genetic background, life style and gut microbiome
- Principal Investigator
  
  野々村祝夫
- Project Period (FY)
  2024 – 2025
- Research Category
  
  Grant-in-Aid for Scientific Research (B)
- Review Section
  
  Basic Section 56030:Urology-related
- Research Institution
  Osaka University
腸内環境に基づいて抗悪性腫瘍剤の治療反応性を層別化する基盤的研究Principal Investigator
- Principal Investigator
  
  柴知史
- Project Period (FY)
  2022 – 2025
- Research Category
  
  Grant-in-Aid for Early-Career Scientists
- Review Section
  
  Basic Section 54010:Hematology and medical oncology-related
- Research Institution
  National Cancer Center Japan
Basis for the research of identification of gut microbiota in pancreatic cancer and clinical applicationPrincipal Investigator
- Principal Investigator
  
  Satoshi Shiba
- Project Period (FY)
  2018 – 2021
- Research Category
  
  Grant-in-Aid for Early-Career Scientists
- Review Section
  
  Basic Section 53010:Gastroenterology-related
- Research Institution
  National Cancer Center Japan

All 2025 2024 2023 2022 2020 2019

All Journal Article Presentation

[Journal Article] Microbiome and Colorectal Cancer in Humans: A Review of Recent Studies2025
- Author(s)
  Hiroyuki Takamaru、Cynthia Tsay、Satoshi Shiba、Shinichi Yachida、Yutaka Saito
- Journal Title
  
  Journal of the Anus, Rectum and Colon
  
  Volume: 9 Issue: 1 Pages: 20-24
- DOI
  10.23922/jarc.2024-080
- ISSN
  2432-3853
- Year and Date
  2025-01-25
- Language
  English
- Peer Reviewed / Open Access / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-22H04925, KAKENHI-PROJECT-22K16336
[Journal Article] Fusobacterium species are distinctly associated with patients with Lynch syndrome colorectal cancer2024
- Author(s)
  Felix Salim、Sayaka Mizutani、Satoshi Shiba、Hiroyuki Takamaru、Masayoshi Yamada、Takeshi Nakajima、Tatsuo Yachida、Tomoyoshi Soga、Yutaka Saito、Shinji Fukuda、Shinichi Yachida、Takuji Yamada
- Journal Title
  
  iScience
  
  Volume: 27(7) Issue: 7 Pages: 110181-110181
- DOI
  10.1016/j.isci.2024.110181
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-22H04925, KAKENHI-PROJECT-19K08416, KAKENHI-PROJECT-22K16336, KAKENHI-PROJECT-23KJ0957
[Journal Article] Intestinal Bacteria Fluctuating in Early-Stage Colorectal Cancer Carcinogenesis are Associated with Diet in Healthy Adults2024
- Author(s)
  Nobuhiro Narii、Ling Zha、Tomotaka Sobue、Tetsuhisa Kitamura、Masayo Komatsu、Yoshimitsu Shimomura、Satoshi Shiba、Sayaka Mizutani、Takuji Yamada、Shinichi Yachida
- Journal Title
  
  Nutrition and Cancer
  
  Volume: 76 Issue: 6 Pages: 521-528
- DOI
  10.1080/01635581.2024.2344257
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-22H04925, KAKENHI-PROJECT-22K16336
[Journal Article] Dynamics of the gut microbiome in FAP patients undergoing intensive endoscopic reduction of polyp burden2024
- Author(s)
  Sayaka Mizutani、Ayako Tamaki、Satoshi Shiba、Felix Salim、Masayoshi Yamada、Hiroyuki Takamaru、Takeshi Nakajima、Naohisa Yoshida、Shoko Ikuta、Tatsuo Yachida、Tatsuhiro Shibata、Tomoyoshi Soga、Yutaka Saito、Shinji Fukuda、Hideki Ishikawa、Takuji Yamada、Shinichi Yachida
- Journal Title
  
  Gut
  
  Volume: 74 Issue: 2 Pages: 335-338
- DOI
  10.1136/gutjnl-2024-332381
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-22H04925, KAKENHI-PROJECT-23K24798, KAKENHI-PROJECT-19K08416, KAKENHI-PROJECT-22K16336, KAKENHI-PROJECT-23KJ0957
[Journal Article] Variability in non-tumor areas of colorectal cancer patients as revealed by endoscopic intestinal step biopsies2024
- Author(s)
  Shoko Ikuta、Yutaka Saito、So Takata、Yoichiro Nakatani、Izumi Nagatomo、Satoshi Shiba、Yoshito Takeda、Yasushi Totoki、Sayaka Mizutani、Hironori Sunakawa、Hiroaki Ikematsu、Hiroyuki Takamaru、Atsushi Kumanogoh、Shinichi Yachida
- Journal Title
  
  Molecular Cancer
  
  Volume: 23(1) Issue: 1 Pages: 249-249
- DOI
  10.1186/s12943-024-02159-9
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-22H04925, KAKENHI-PROJECT-19K08416, KAKENHI-PROJECT-22K16336, KAKENHI-PROJECT-23KJ0957
[Journal Article] Prognostic significance of serum fucosylated pro-haptoglobin in advanced renal cell carcinoma patients treated with immune checkpoint inhibitors2023
- Author(s)
  Kato Taigo、Morishita Koichi、Tomiyama Eisuke、Hayashibara Ayumu、Ishizuya Yu、Yamamoto Yoshiyuki、Hatano Koji、Kawashima Atsunari、Fukuhara Shinichiro、Nonomura Norio、Miyoshi Eiji、Fujita Kazutoshi
- Journal Title
  
  Scientific Reports
  
  Volume: 13 Issue: 1 Pages: 17239-17239
- DOI
  10.1038/s41598-023-42739-1
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-23K24228, KAKENHI-PROJECT-23K24471
[Journal Article] Efficient and accurate KRAS genotyping using digital PCR combined with melting curve analysis for ctDNA from pancreatic cancer patients2023
- Author(s)
  Tanaka Junko、Nakagawa Tatsuo、Harada Kunio、Morizane Chigusa、Tanaka Hidenori、Shiba Satoshi、Ohba Akihiro、Hijioka Susumu、Takai Erina、Yachida Shinichi、Kamura Yoshio、Ishida Takeshi、Yokoi Takahide、Uematsu Chihiro
- Journal Title
  
  Scientific Reports
  
  Volume: 13 Issue: 1
- DOI
  10.1038/s41598-023-30131-y
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-22K16336
[Journal Article] Leveraging explainable AI for gut microbiome-based colorectal cancer classification2023
- Author(s)
  Rynazal Ryza、Fujisawa Kota、Shiroma Hirotsugu、Salim Felix、Mizutani Sayaka、Shiba Satoshi、Yachida Shinichi、Yamada Takuji
- Journal Title
  
  Genome Biology
  
  Volume: 24 Issue: 1
- DOI
  10.1186/s13059-023-02858-4
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-19K08416, KAKENHI-PROJECT-22H04925, KAKENHI-PROJECT-19J40249, KAKENHI-PROJECT-22K16336
[Journal Article] Surgical Treatment for Colorectal Cancer Partially Restores Gut Microbiome and Metabolome Traits.2022
- Author(s)
  Shiroma H, Shiba S, Erawijantari PP, Takamaru H, Yamada M, Sakamoto T, Kanemitsu Y, Mizutani S, Soga T, Saito Y, Shibata T, Fukuda S, Yachida S, Yamada T.
- Journal Title
  
  mSystems
  
  Volume: 7 Issue: 2
- DOI
  10.1128/msystems.00018-22
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-18K15800, KAKENHI-PROJECT-19J40249, KAKENHI-PROJECT-19K08416, KAKENHI-PROJECT-16H06279, KAKENHI-PROJECT-22K16336
[Journal Article] Mediation effect of intestinal microbiota on the relationship between fiber intake and colorectal cancer2022
- Author(s)
  Shimomura Yoshimitsu、Zha Ling、Komukai Sho、Narii Nobuhiro、Sobue Tomotaka、Kitamura Tetsuhisa、Shiba Satoshi、Mizutani Sayaka、Yamada Takuji、Sawada Norie、Yachida Shinichi
- Journal Title
  
  International Journal of Cancer
  
  Volume: 152 Issue: 9 Pages: 1752-1762
- DOI
  10.1002/ijc.34398
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-19K08416, KAKENHI-PROJECT-22K16336, KAKENHI-PROJECT-22H04925, KAKENHI-PROJECT-19J40249
[Journal Article] Association Between Diet and <i>Fusobacterium nucleatum</i> in the Feces of Healthy Adults: A Hospital-based Cross-sectional Study2022
- Author(s)
  Narii Nobuhiro、Zha Ling、Sobue Tomotaka、Kitamura Tetsuhisa、Shiba Satoshi、Mizutani Sayaka、Yamada Takuji、Yachida Shinichi
- Journal Title
  
  Cancer Prevention Research
  
  Volume: 16 Issue: 2 Pages: 119-126
- DOI
  10.1158/1940-6207.capr-22-0399
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-19K08416, KAKENHI-PROJECT-22K16336, KAKENHI-PROJECT-22H04925, KAKENHI-PROJECT-19J40249
[Journal Article] Feasibility study of nivolumab as neoadjuvant chemotherapy for locally esophageal carcinoma: FRONTiER (JCOG1804E)2020
- Author(s)
  Yamamoto Shun、Kato Ken、Daiko Hiroyuki、Kojima Takashi、Hara Hiroki、Abe Tetsuya、Tsubosa Yasuhiro、Nagashima Kengo、Aoki Kazunori、Mizoguchi Yukihiro、Kitano Shigehisa、Yachida Shinichi、Shiba Satoshi、Kitagawa Yuko
- Journal Title
  
  Future Oncology
  
  Volume: 16 Issue: 19 Pages: 1351-1357
- DOI
  10.2217/fon-2020-0189
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-18K15800
[Journal Article] Influence of gastrectomy for gastric cancer treatment on faecal microbiome and metabolome profiles2020
- Author(s)
  Erawijantari Pande Putu、Mizutani Sayaka、Shiroma Hirotsugu、Shiba Satoshi、Nakajima Takeshi、Sakamoto Taku、Saito Yutaka、Fukuda Shinji、Yachida Shinichi、Yamada Takuji
- Journal Title
  
  Gut
  
  Volume: - Issue: 8 Pages: 1-12
- DOI
  10.1136/gutjnl-2019-319188
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-19K08416, KAKENHI-PUBLICLY-18H04805, KAKENHI-PROJECT-19J40249, KAKENHI-PROJECT-18K15800, KAKENHI-PROJECT-20H03662
[Journal Article] Meta-analysis of fecal metagenomes reveals global microbial signatures that are specific for colorectal cancer2019
- Author(s)
  Wirbel Jakob, Shiba Satoshi, et al.
- Journal Title
  
  Nature Medicine
  
  Volume: 25 Issue: 4 Pages: 679-689
- DOI
  10.1038/s41591-019-0406-6
- Peer Reviewed / Open Access / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-18K15800, KAKENHI-PROJECT-16H06279
[Journal Article] Metagenomic analysis of colorectal cancer datasets identifies cross-cohort microbial diagnostic signatures and a link with choline degradation2019
- Author(s)
  Andrew Maltez Thomas, Paolo Manghi, Francesco Asnicar, Edoardo Pasolli, Federica Armanini, Moreno Zolfo, Francesco Beghini, Serena Manara, Nicolai Karcher, Chiara Pozzi, Sara Gandini, Davide Serrano, Sonia Tarallo, Antonio Francavilla, Gaetano Gallo, 他25名
- Journal Title
  
  Nature medicine
  
  Volume: 25 Issue: 4 Pages: 667-678
- DOI
  10.1038/s41591-019-0405-7
- Peer Reviewed / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-16H06279, KAKENHI-PROJECT-18K15800
[Journal Article] Metagenomic and metabolomic analyses reveal distinct stage-specific phenotypes of the gut microbiota in colorectal cancer2019
- Author(s)
  Yachida Shinichi、Mizutani Sayaka、Shiroma Hirotsugu、Shiba Satoshi、Nakajima Takeshi、Sakamoto Taku、Saito Yutaka、Fukuda Shinji、Shibata Tatsuhiro、Yamada Takuji
- Journal Title
  
  Nature Medicine
  
  Volume: 25 Issue: 6 Pages: 968-976
- DOI
  10.1038/s41591-019-0458-7
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-19K08416, KAKENHI-PROJECT-18K15800, KAKENHI-PUBLICLY-18H04805, KAKENHI-PROJECT-16H06373, KAKENHI-PROJECT-19J40249, KAKENHI-PROJECT-16H06279
[Presentation] 便マルチオミクス解析を用いた大腸多段階発癌に関連する腸内微生物・微小環境の大腸癌術後における変化2022
- Author(s)
  高丸博之、柴知史、齋藤豊
- Organizer
  JDDW2022
- Data Source
  KAKENHI-PROJECT-22K16336
[Presentation] 便メタゲノムおよびメタボローム解析による大腸多段階発癌における腸内微生物叢・微小環境の特徴と可能性2020
- Author(s)
  高丸博之,　柴知史,　坂本琢,　山田真善,　斎藤豊
- Organizer
  2020年度日本消化器関連学会（JDDW 2020）
- Data Source
  KAKENHI-PROJECT-18K15800
[Presentation] FRONTiER: A feasibility trial of nivolumab with neoadjuvant CF or DCF therapy for locally advanced esophageal carcinoma (JCOG1804E) - The short-term results of cohort A and B.2020
- Author(s)
  Yamamoto S, Kato K, Daiko H, Kojima T, Hara H, Abe T, Tsubosa Y, Kawakubo H, Fujita T, Fukuda T, Kadowaki S, Tsushima T, Hamamoto Y, Nagashima K, Aoki K, Mizoguchi Y, Kitano S, Yachida S, Shiba S, Kitagawa Y
- Organizer
  2021 Gastrointestinal Cancers Symposium.
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-18K15800

1. 野々村祝夫 (30263263)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
2. 山田拓司 (10437262)

# of Collaborated Projects: 1 results

# of Collaborated Products: 3 results
3. 谷内田真一 (20359920)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
4. 松下慎 (40824785)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
5. 藤田和利 (50636181)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
6. 波多野浩士 (60762234)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
7. 岡田随象 (70727411)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
8. 中村昇太 (90432434)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
9. ITOH Takehiko

# of Collaborated Projects: 0 results

# of Collaborated Products: 3 results
10. 三善英知

# of Collaborated Projects: 0 results

# of Collaborated Products: 1 results
11. 水谷紗弥佳

# of Collaborated Projects: 0 results

# of Collaborated Products: 5 results

Shiba Satoshi 柴 知史

Satoshi Shiba 柴 知史

Research Projects

Research Products

Co-Researchers

Diagnostic strategy for prostate cancer based on multifaceted analyses of genetic background, life style and gut microbiome

Principal Investigator

Project Period (FY)

Research Category

Review Section

Research Institution

腸内環境に基づいて抗悪性腫瘍剤の治療反応性を層別化する基盤的研究Principal Investigator

Principal Investigator

Project Period (FY)

Research Category

Review Section

Research Institution

Basis for the research of identification of gut microbiota in pancreatic cancer and clinical applicationPrincipal Investigator

Principal Investigator

Project Period (FY)

Research Category

Review Section

Research Institution

[Journal Article] Microbiome and Colorectal Cancer in Humans: A Review of Recent Studies2025

Author(s)

Journal Title

DOI

ISSN

Year and Date

Language

Data Source

[Journal Article] Fusobacterium species are distinctly associated with patients with Lynch syndrome colorectal cancer2024

Author(s)

Journal Title

DOI

Data Source

[Journal Article] Intestinal Bacteria Fluctuating in Early-Stage Colorectal Cancer Carcinogenesis are Associated with Diet in Healthy Adults2024

Author(s)

Journal Title

DOI

Data Source

[Journal Article] Dynamics of the gut microbiome in FAP patients undergoing intensive endoscopic reduction of polyp burden2024

Author(s)

Journal Title

DOI

Data Source

[Journal Article] Variability in non-tumor areas of colorectal cancer patients as revealed by endoscopic intestinal step biopsies2024

Author(s)

Journal Title

DOI

Data Source

[Journal Article] Prognostic significance of serum fucosylated pro-haptoglobin in advanced renal cell carcinoma patients treated with immune checkpoint inhibitors2023

Author(s)

Journal Title

DOI

Data Source

[Journal Article] Efficient and accurate KRAS genotyping using digital PCR combined with melting curve analysis for ctDNA from pancreatic cancer patients2023

Author(s)

Journal Title

DOI

Data Source

[Journal Article] Leveraging explainable AI for gut microbiome-based colorectal cancer classification2023

Author(s)

Journal Title

DOI

Data Source

[Journal Article] Surgical Treatment for Colorectal Cancer Partially Restores Gut Microbiome and Metabolome Traits.2022

Author(s)

Journal Title

DOI

Data Source

[Journal Article] Mediation effect of intestinal microbiota on the relationship between fiber intake and colorectal cancer2022

Author(s)

Journal Title

DOI

Data Source

[Journal Article] Association Between Diet and <i>Fusobacterium nucleatum</i> in the Feces of Healthy Adults: A Hospital-based Cross-sectional Study2022

Author(s)

Journal Title

DOI

Shiba Satoshi 柴知史

Satoshi Shiba 柴知史