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KINOSHITA Takaaki  木下 貴明

ORCIDConnect your ORCID iD *help
Researcher Number 00803181
Affiliation (Current) 2025: 長崎大学, 高度感染症研究センター, 助教
Affiliation (based on the past Project Information) *help 2022 – 2024: 長崎大学, 高度感染症研究センター, 助教
2021: 長崎大学, 感染症共同研究拠点, 助教
Review Section/Research Field
Principal Investigator
Basic Section 58020:Hygiene and public health-related: including laboratory approach
Except Principal Investigator
Basic Section 38040:Bioorganic chemistry-related / Medium-sized Section 49:Pathology, infection/immunology, and related fields
Keywords
Principal Investigator
糖鎖 / アレナウイルス / コロナウイルス / SARS-CoV-2 / 新型コロナウイルス
Except Principal Investigator
ウイルス変異 / SARS-CoV-2 / Pradimicin / 分子間相互作用 / 糖鎖 … More / 天然物 / 抗ウイルス薬 / コウモリ / ガボン / Virome / 新興感染症 / アフリカ / ウイルス / 人獣共通感染症 Less
  • Research Projects

    (4 results)
  • Research Products

    (11 results)
  • Co-Researchers

    (6 People)
  •  Development of mutation-tolerant antiviral leads targeting glycans

    • Principal Investigator
      中川 優
    • Project Period (FY)
      2024 – 2026
    • Research Category
      Grant-in-Aid for Scientific Research (C)
    • Review Section
      Basic Section 38040:Bioorganic chemistry-related
    • Research Institution
      Nagoya University
  •  アレナウイルス糖タンパク質の糖鎖修飾パターンの解析Principal Investigator

    • Principal Investigator
      木下 貴明
    • Project Period (FY)
      2024 – 2026
    • Research Category
      Grant-in-Aid for Early-Career Scientists
    • Review Section
      Basic Section 58020:Hygiene and public health-related: including laboratory approach
    • Research Institution
      Nagasaki University
  •  中部アフリカに生息する野生動物のVirome解析による新興ウイルスの生態解明

    • Principal Investigator
      安田 二朗
    • Project Period (FY)
      2022 – 2025
    • Research Category
      Fund for the Promotion of Joint International Research (Fostering Joint International Research (B))
    • Review Section
      Medium-sized Section 49:Pathology, infection/immunology, and related fields
    • Research Institution
      Nagasaki University
  •  Elucidation of novel molecular mechanisms involved in coronavirus transmission to humansPrincipal Investigator

    • Principal Investigator
      KINOSHITA Takaaki
    • Project Period (FY)
      2021 – 2023
    • Research Category
      Grant-in-Aid for Early-Career Scientists
    • Review Section
      Basic Section 58020:Hygiene and public health-related: including laboratory approach
    • Research Institution
      Nagasaki University

All 2025 2024 2023 2022 2021

All Journal Article Presentation

  • [Journal Article] Molecular basis of N-glycan recognition by pradimicin a and its potential as a SARS-CoV-2 entry inhibitor2024

    • Author(s)
      Nakagawa Yu、Fujii Masato、Ito Nanaka、Ojika Makoto、Akase Dai、Aida Misako、Kinoshita Takaaki、Sakurai Yasuteru、Yasuda Jiro、Igarashi Yasuhiro、Ito Yukishige
    • Journal Title

      Bioorganic and Medicinal Chemistry

      Volume: 105 Pages: 117732-117732

    • DOI

      10.1016/j.bmc.2024.117732

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-23K23463, KAKENHI-PROJECT-24K08728
  • [Journal Article] Co-infection of SARS-CoV-2 and influenza virus causes more severe and prolonged pneumonia in hamsters2021

    • Author(s)
      Kinoshita Takaaki、Watanabe Kenichi、Sakurai Yasuteru、Nishi Kodai、Yoshikawa Rokusuke、Yasuda Jiro
    • Journal Title

      Scientific Reports

      Volume: 11 Issue: 1

    • DOI

      10.1038/s41598-021-00809-2

    • NAID

      120007185292

    • Peer Reviewed / Open Access
    • Data Source
      KAKENHI-PROJECT-21K17270
  • [Presentation] Histological analysis of male accessory reproductive glands of Egyptian Rousette Bat -Unique morphology in the seminal vesicles and urethra glands.2025

    • Author(s)
      Kumiko Koyama, Junko Nio-Kobayashi, Takaaki Kinoshita, Yuji Fujii, Hiroki Nakata, Jiro Yasuda
    • Organizer
      APPW2025
    • Data Source
      KAKENHI-PROJECT-22KK0116
  • [Presentation] オリゴマンノースへの結合を介したPradimicin Aのウイルス感染阻害2024

    • Author(s)
      木下貴明、櫻井康晃、中川 優、五十嵐康弘、安田二朗
    • Organizer
      第71回日本ウイルス学会学術集会
    • Data Source
      KAKENHI-PROJECT-24K20196
  • [Presentation] 糖鎖を標的とする新型コロナウイルス薬の開発を目指したプラディミシンの化学修飾2024

    • Author(s)
      勝 理帆,大矢柚香,宮西 航,木下貴明,櫻井康晃,安田二朗,五十嵐康弘,伊藤幸成,中川 優
    • Organizer
      糖鎖科学中部拠点第20回若手の力フォーラム
    • Data Source
      KAKENHI-PROJECT-24K08728
  • [Presentation] グリコサミノグリカンによるアレナウイルス感染阻害2024

    • Author(s)
      木下貴明、安田二朗
    • Organizer
      第43回日本糖質学会年会
    • Data Source
      KAKENHI-PROJECT-24K20196
  • [Presentation] N-Glycan Recognition and Anti-SARS-CoV-2 Activity of Pradimicins2024

    • Author(s)
      Riho Katsu, Masato Fujii, Nanaka Ito, Makoto Ojika, Dai Akase, Misako Aida, Takaaki Kinoshita, Yasuteru Sakurai, Jiro Yasuda, Yasuhiro Igarashi, Yukishige Ito, Yu Nakagawa
    • Organizer
      Glyco-core Symposium 2024
    • Int'l Joint Research
    • Data Source
      KAKENHI-PROJECT-24K08728
  • [Presentation] 糖鎖を標的とする抗SARS-CoV-2薬の開発を目指したプラディミシンAの構造修飾2024

    • Author(s)
      勝 理帆,大矢柚香,宮西 航,木下貴明,櫻井康晃,安田二朗,五十嵐康弘,伊藤幸成,中川 優
    • Organizer
      第43回日本糖質学会年会
    • Data Source
      KAKENHI-PROJECT-24K08728
  • [Presentation] Pradimicin-A inhibits SARS-CoV-2 infection through binding to oligomannose on viral proteins.2023

    • Author(s)
      Takaaki Kinoshita, Yasuteru Sakurai, Yu Nakagawa, Yasuhiro Igarashi, and Jiro Yasuda
    • Organizer
      The 70th Annual Meeting of the Japanese Society for Virology
    • Data Source
      KAKENHI-PROJECT-21K17270
  • [Presentation] SARS-CoV-2感染ハムスターモデルを用いた変異株間における性状比較2022

    • Author(s)
      木下貴明, 櫻井康晃, 渡邉 謙一, 安田二朗
    • Organizer
      九州微生物研究フォーラム 2022
    • Data Source
      KAKENHI-PROJECT-21K17270
  • [Presentation] Co-infection of SARS-CoV-2 and influenza virus causes more severe and prolonged pneumonia in hamsters2021

    • Author(s)
      Kinoshita Takaaki、Watanabe Kenichi、Sakurai Yasuteru、Nishi Kodai、Yoshikawa Rokusuke、Yasuda Jiro
    • Organizer
      The 68th Annual Meeting of the Japanese Society for Virology.
    • Data Source
      KAKENHI-PROJECT-21K17270
  • 1.  安田 二朗 (10282518)
    # of Collaborated Projects: 1 results
    # of Collaborated Products: 1 results
  • 2.  櫻井 康晃 (00818338)
    # of Collaborated Projects: 1 results
    # of Collaborated Products: 0 results
  • 3.  吉川 禄助 (20816821)
    # of Collaborated Projects: 1 results
    # of Collaborated Products: 0 results
  • 4.  阿部 遥 (90554353)
    # of Collaborated Projects: 1 results
    # of Collaborated Products: 0 results
  • 5.  中川 優 (90452284)
    # of Collaborated Projects: 1 results
    # of Collaborated Products: 3 results
  • 6.  伊藤 幸成
    # of Collaborated Projects: 0 results
    # of Collaborated Products: 1 results

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