UCHIDA TAKURO 内田宅郎

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Uchida Takuro 内田宅郎

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Researcher Number	00827967
Other IDs
Affiliation (Current)	2025: 大分大学, グローカル感染症研究センター, 講師
Affiliation (based on the past Project Information) *help	2023 – 2025: 大分大学, グローカル感染症研究センター, 講師 2022: 広島大学, 病院(医), 医科診療医
Review Section/Research Field	Principal Investigator Basic Section 53010:Gastroenterology-related Except Principal Investigator Basic Section 53010:Gastroenterology-related
Keywords	Principal Investigator HBV / Basal Core Promoter変異 / Precore変異 / ヒト肝細胞キメラマウス / HBV再活性化 / ERストレス / BCP変異 / PC変異 / 劇症肝炎 / B型肝炎 / PC/BCP変異 Except Principal Investigator オルガノイド / 発癌

分化/リプログラミングモデル構築による慢性胃炎機能回復と発癌予防標的の同定
- Principal Investigator
  
  平下有香
- Project Period (FY)
  2025 – 2027
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Review Section
  
  Basic Section 53010:Gastroenterology-related
- Research Institution
  Oita University
HBV直接的肝細胞障害関連遺伝子とウイルスの相互作用の解明Principal Investigator
- Principal Investigator
  
  内田宅郎
- Project Period (FY)
  2024 – 2026
- Research Category
  
  Grant-in-Aid for Early-Career Scientists
- Review Section
  
  Basic Section 53010:Gastroenterology-related
- Research Institution
  Oita University
Elucidation of the mechanism of direct cytopathic effect of HBVPrincipal Investigator
- Principal Investigator
  
  Uchida Takuro
- Project Period (FY)
  2022 – 2023
- Research Category
  
  Grant-in-Aid for Early-Career Scientists
- Review Section
  
  Basic Section 53010:Gastroenterology-related
- Research Institution
  Oita University
  Hiroshima University

All 2024 2023 2022

All Journal Article Presentation Book

[Book] ウイルス性肝炎学 2023 ―最新の病態・診断・治療情報―V.各論 HBV 遺伝子型と臨床像2023
- Author(s)
  内田宅郎岡志郎
- Total Pages
  6
- Publisher
  日本臨牀社
- Data Source
  KAKENHI-PROJECT-22K15967
[Journal Article] Circulating thrombospondin 2 as a predictor of hepatocellular carcinoma in hepatitis B patients undergoing nucleos(t)ide analog therapy2024
- Author(s)
  Okumura Taiki、Kimura Takefumi、Ichikawa Yuki、Iwadare Takanobu、Wakabayashi Shun-ichi、Kobayashi Hiroyuki、Yamashita Yuki、Uchida Takuro、Pydi Sai P.、Tanaka Naoki、Umemura Takeji
- Journal Title
  
  Scientific Reports
  
  Volume: 14 Issue: 1 Pages: 25584-25584
- DOI
  10.1038/s41598-024-76532-5
- Peer Reviewed / Open Access / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-22K20884, KAKENHI-PROJECT-24K11087, KAKENHI-PROJECT-24K18920
[Journal Article] Alteration of Gene Expression After Entecavir and Pegylated Interferon Therapy in HBV-Infected Chimeric Mouse Liver2024
- Author(s)
  Bao Huarui、Murakami Serami、Tsuge Masataka、Uchida Takuro、Uchikawa Shinsuke、Fujino Hatsue、Ono Atsushi、Murakami Eisuke、Kawaoka Tomokazu、Miki Daiki、Hayes Clair Nelson、Oka Shiro
- Journal Title
  
  Viruses
  
  Volume: 16 Issue: 11 Pages: 1743-1743
- DOI
  10.3390/v16111743
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-24K11112, KAKENHI-PROJECT-24K18920
[Journal Article] Interferon alpha induces a stronger antiviral effect than interferon lambda in HBV/HDV infected humanized mice2024
- Author(s)
  Duehren Sarah、Uchida Takuro、Tsuge Masataka、Hiraga Nobuhiko、Uprichard Susan L.、Etzion Ohad、Glenn Jeffrey、Koh Christopher、Heller Theo、Cotler Scott J.、Oka Shiro、Chayama Kazuaki、Dahari Harel
- Journal Title
  
  Virus Research
  
  Volume: 349 Pages: 199451-199451
- DOI
  10.1016/j.virusres.2024.199451
- Peer Reviewed / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-24K18920
[Journal Article] HBV with precore and basal core promoter mutations exhibits a high replication phenotype and causes ER stress-mediated cell death in humanized liver chimeric mice2023
- Author(s)
  Uchida Takuro、Imamura Michio、Hayes C. Nelson、Suehiro Yosuke、Teraoka Yuji、Ohya Kazuki、Aikata Hiroshi、Abe-Chayama Hiromi、Ishida Yuji、Tateno Chise、Hara Yuichi、Hino Keisuke、Okamoto Toru、Matsuura Yoshiharu、Aizaki Hideki、Wake Kenjiro、Kohara Michinori、Liang T. Jake、Oka Shiro、Chayama Kazuaki
- Journal Title
  
  Hepatology
  
  Volume: 78 Issue: 3 Pages: 929-942
- DOI
  10.1097/hep.0000000000000335
- Data Source
  KAKENHI-PROJECT-22K15967
[Presentation] ヒト肝細胞キメラマウスにおけるHBV/HDV感染のウイルス動態2024
- Author(s)
  内田宅郎、柘植雅貴、村上和成
- Organizer
  第60回日本肝臓学会総会
- Data Source
  KAKENHI-PROJECT-24K18920
[Presentation] HBV感染による直接的肝細胞障害と肝細胞内の遺伝子発現変化2024
- Author(s)
  内田宅郎、柘植雅貴、岩尾正雄、荒川光江、遠藤美月、岡志郎、村上和成
- Organizer
  第110回日本消化器病学会総会
- Data Source
  KAKENHI-PROJECT-24K18920
[Presentation] Mathematical modeling of hepatitis B and D viral kinetics during coinfection in humanized mice suggests differences in their infectivity2024
- Author(s)
  Ashish Goyal, Takuro Uchida, Grace N Makokha, Hiromi Abe-Chayama, Yuji Ishida, Chise Tateno, Harel Dahari1, Kazuaki Chayama
- Organizer
  EASL CONGRESS 2024
- Data Source
  KAKENHI-PROJECT-24K18920
[Presentation] HBV with precore and basal core promoter mutations exhibits a high replication phenotypeand causes ER stress-mediated cell deathin humanized liver chimeric mice2023
- Author(s)
  Takuro Uchida、Yuji Ishida, Chise Tateno, Hideki Aizaki, T. Jake Liang, Kazuaki Chayama, Shiro Oka, Kazunari Murakami
- Organizer
  International HBV Meeting 2023
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-22K15967
[Presentation] Basal core promoterおよびprecore変異型HBVは小胞体ストレス応答を介し肝細胞を直接障害する2023
- Author(s)
  内田宅郎、今村道雄、岡志郎
- Organizer
  第59回日本肝臓学会総会
- Data Source
  KAKENHI-PROJECT-22K15967
[Presentation] Basal core promoterおよび precore変異型HBVは小胞体ストレス応答を介し肝細胞を直接障害する2023
- Author(s)
  内田　宅郎、今村　道雄、岡　志郎
- Organizer
  第59回日本肝臓学会総会
- Data Source
  KAKENHI-PROJECT-22K15967
[Presentation] ACCUMULATION OF HEPATITIS B SURFACE ANTIGEN PROVOKES ER STRESS MEDIATED CELL DEATH IN BASAL CORE PROMOTER AND PRECORE MUTATED HEPATITIS B VIRUS INFECTION2022
- Author(s)
  Takuro Uchida, Michio Imamura, Yuji Teraoka,Hatsue Fujino,Takashi Nakahara,Atsushi Ono,Eisuke Murakami,Masami Yamauchi,Tomokazu Kawaoka,Daiki Miki,Hiromi Abe-Chayama,C. Nelson Hayes, Hiroshi Aikata,Yuji Ishida,Chise Tateno,HoJoong Song,Yohei Miyayama,Makoto Hijikata,Kazuaki Chayama
- Organizer
  The Liver Meeting 2022
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-22K15967

1. 平下有香 (70771955)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
2. 塚本善之 (00433053)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
3. 小坂聡太郎 (60835700)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
4. 木村岳史

# of Collaborated Projects: 0 results

# of Collaborated Products: 1 results
5. 柘植雅貴

# of Collaborated Projects: 0 results

# of Collaborated Products: 1 results

UCHIDA TAKURO 内田 宅郎

Uchida Takuro 内田 宅郎

Research Projects

Research Products

Co-Researchers

分化/リプログラミングモデル構築による慢性胃炎機能回復と発癌予防標的の同定

Principal Investigator

Project Period (FY)

Research Category

Review Section

Research Institution

HBV直接的肝細胞障害関連遺伝子とウイルスの相互作用の解明Principal Investigator

Principal Investigator

Project Period (FY)

Research Category

Review Section

Research Institution

Elucidation of the mechanism of direct cytopathic effect of HBVPrincipal Investigator

Principal Investigator

Project Period (FY)

Research Category

Review Section

Research Institution

[Book] ウイルス性肝炎学 2023 ―最新の病態・診断・治療情報―V.各 論 HBV 遺伝子型と臨床像2023

Author(s)

Total Pages

Publisher

Data Source

[Journal Article] Circulating thrombospondin 2 as a predictor of hepatocellular carcinoma in hepatitis B patients undergoing nucleos(t)ide analog therapy2024

Author(s)

Journal Title

DOI

Data Source

[Journal Article] Alteration of Gene Expression After Entecavir and Pegylated Interferon Therapy in HBV-Infected Chimeric Mouse Liver2024

Author(s)

Journal Title

DOI

Data Source

[Journal Article] Interferon alpha induces a stronger antiviral effect than interferon lambda in HBV/HDV infected humanized mice2024

Author(s)

Journal Title

DOI

Data Source

[Journal Article] HBV with precore and basal core promoter mutations exhibits a high replication phenotype and causes ER stress-mediated cell death in humanized liver chimeric mice2023

Author(s)

Journal Title

DOI

Data Source

[Presentation] ヒト肝細胞キメラマウスにおけるHBV/HDV感染のウイルス動態2024

Author(s)

Organizer

Data Source

[Presentation] HBV感染による直接的肝細胞障害と肝細胞内の遺伝子発現変化2024

Author(s)

Organizer

Data Source

[Presentation] Mathematical modeling of hepatitis B and D viral kinetics during coinfection in humanized mice suggests differences in their infectivity2024

Author(s)

Organizer

Data Source

[Presentation] HBV with precore and basal core promoter mutations exhibits a high replication phenotypeand causes ER stress-mediated cell deathin humanized liver chimeric mice2023

Author(s)

Organizer

Data Source

[Presentation] Basal core promoterおよびprecore変異型HBVは小胞体ストレス応答を介し肝細胞を直接障害する2023

Author(s)

Organizer

Data Source

[Presentation] Basal core promoterおよび precore変異型HBVは小胞体ストレス応答を介し肝細胞を直接障害する2023

Author(s)

Organizer

Data Source

[Presentation] ACCUMULATION OF HEPATITIS B SURFACE ANTIGEN PROVOKES ER STRESS MEDIATED CELL DEATH IN BASAL CORE PROMOTER AND PRECORE MUTATED HEPATITIS B VIRUS INFECTION2022

Author(s)

Organizer

Data Source

UCHIDA TAKURO 内田宅郎

Uchida Takuro 内田宅郎

[Book] ウイルス性肝炎学 2023 ―最新の病態・診断・治療情報―V.各論 HBV 遺伝子型と臨床像2023