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Seki Takao  関 崇生

ORCIDConnect your ORCID iD *help
Researcher Number 00832205
Other IDs
Affiliation (Current) 2025: 東邦大学, 医学部, 助教
Affiliation (based on the past Project Information) *help 2025: 東邦大学, 医学部, 助教
2021 – 2022: 東邦大学, 医学部, 助教
2020: 国立研究開発法人理化学研究所, 生命医科学研究センター, 特別研究員
Review Section/Research Field
Principal Investigator
Basic Section 49030:Experimental pathology-related / Basic Section 48040:Medical biochemistry-related
Except Principal Investigator
Basic Section 49030:Experimental pathology-related
Keywords
Principal Investigator
免疫 / TNFレセプターファミリー / 成熟 / 樹状細胞 / 胸腺 / 自己免疫
Except Principal Investigator
MIB2 / cFLIPL / MLKL / アポトーシス … More / 多光子顕微鏡 / 一分子イメージング / イメージング / 1分子イメージング / HMGB1 / トランスジェニックマウス / in vivoイメージング / シスプラチン / SMART / FRET / DAMPs / 全反射顕微鏡 / 1分子イメージング / ネクロプトーシス Less
  • Research Projects

    (3 results)
  • Research Products

    (9 results)
  • Co-Researchers

    (4 People)
  •  FGF18とオステオポンチンを介した肝線維化誘導メカニズムの解明Principal Investigator

    • Principal Investigator
      関 崇生
    • Project Period (FY)
      2025 – 2027
    • Research Category
      Grant-in-Aid for Scientific Research (C)
    • Review Section
      Basic Section 49030:Experimental pathology-related
    • Research Institution
      Toho University
  •  Mechanisms of thymic dendritic cell maturation involved in autoimmune diseasesPrincipal Investigator

    • Principal Investigator
      Seki Takao
    • Project Period (FY)
      2020 – 2021
    • Research Category
      Grant-in-Aid for Early-Career Scientists
    • Review Section
      Basic Section 48040:Medical biochemistry-related
    • Research Institution
      Toho University
      Institute of Physical and Chemical Research
  •  Elucidation of the mechanisms underlying the execution of necroptosis

    • Principal Investigator
      NAKANO Hiroyasu
    • Project Period (FY)
      2020 – 2022
    • Research Category
      Grant-in-Aid for Scientific Research (B)
    • Review Section
      Basic Section 49030:Experimental pathology-related
    • Research Institution
      Toho University

All 2022 2021

All Journal Article Presentation

  • [Journal Article] Generation of transgenic mice expressing a FRET biosensor, SMART, that responds to necroptosis2022

    • Author(s)
      Murai Shin、Takakura Kanako、Sumiyama Kenta、Moriwaki Kenta、Terai Kenta、Komazawa-Sakon Sachiko、Seki Takao、Yamaguchi Yoshifumi、Mikami Tetuo、Araki Kimi、Ohmuraya Masaki、Matsuda Michiyuki、Nakano Hiroyasu
    • Journal Title

      Communications Biology

      Volume: 5 Issue: 1 Pages: 1331-1331

    • DOI

      10.1038/s42003-022-04300-0

    • Peer Reviewed / Open Access
    • Data Source
      KAKENHI-PROJECT-22K07997, KAKENHI-PLANNED-20H05766, KAKENHI-PROJECT-22H04926, KAKENHI-PROJECT-20H03475, KAKENHI-PROJECT-21H02543, KAKENHI-PROJECT-20K05238, KAKENHI-PROJECT-23K21285, KAKENHI-PROJECT-23K21377, KAKENHI-PROJECT-23K24097
  • [Journal Article] Integrative analysis of scRNAs-seq and scATAC-seq revealed transit-amplifying thymic epithelial cells expressing autoimmune regulator2022

    • Author(s)
      Miyao T, Miyauchi M, Kelly ST, Terooatea TW, Ishikawa T, Oh E, Hirai S, Horie K, Takakura Y, Ohki H, Hayama M, Maruyama Y, Seki T, Yabukami H, Yoshida M, Inoue A, Sakaue-Sawano A, Miyawaki A, Muratani M, Minoda A, Akiyama N, and Akiyama T
    • Journal Title

      eLife

      Volume: -

    • Peer Reviewed / Open Access
    • Data Source
      KAKENHI-PROJECT-20K16151
  • [Presentation] FGF18は肝星細胞を活性化して肝線維化を誘導する2022

    • Author(s)
      土屋勇一、関崇生、田中稔、中野裕康
    • Organizer
      第95回日本生化学会大会
    • Invited
    • Data Source
      KAKENHI-PROJECT-20H03475
  • [Presentation] Cell death-deficient mice develop T cell exhaustion2022

    • Author(s)
      関崇生、三好嗣臣、森脇健太、山﨑創、中野裕康
    • Organizer
      第51回 日本免疫学会学術集会
    • Data Source
      KAKENHI-PROJECT-20H03475
  • [Presentation] Mice lacking death ligand-induced cell death develop Pneumocystis pneumonia2022

    • Author(s)
      関崇生、三好嗣臣、森脇健太、山崎創、米原伸、中野裕康
    • Organizer
      第30回日本 Cell Death 学会学術集会
    • Data Source
      KAKENHI-PROJECT-20H03475
  • [Presentation] FGF18はNASH における肝線維化に関与する2021

    • Author(s)
      小林 謙太、土屋 勇一、関 崇生、駒澤 幸子、西山 千春、三上 哲夫、今村 亨、田中 稔、中野 裕康
    • Organizer
      第29回日本Cell Death学会学術集会
    • Data Source
      KAKENHI-PROJECT-20H03475
  • [Presentation] 肝細胞特異的cFLIP欠損はチオアセトアミド投与による慢性肝障害と肝線維化を亢進させる2021

    • Author(s)
      土屋勇一、小林謙太、関崇生、駒澤幸子、西山千春、三上哲夫、今村亨、田中稔、中野裕康
    • Organizer
      第94回日本生化学会大会
    • Data Source
      KAKENHI-PROJECT-20K16151
  • [Presentation] 肝細胞特異的cFLIP欠損はチオアセトアミド投与による慢性肝障害と肝線維化を亢進させる2021

    • Author(s)
      土屋 勇一、小林 謙太、関 崇生、駒澤 幸子、西山 千春、三上 哲夫、今村 亨、田中 稔、中野 裕康
    • Organizer
      第94回日本生化学会大会
    • Data Source
      KAKENHI-PROJECT-20H03475
  • [Presentation] FGF18はNASH における肝線維化に関与する2021

    • Author(s)
      小林謙太、土屋勇一、関崇生、駒澤幸子、西山千春、三上哲夫、今村亨、田中稔、中野裕康
    • Organizer
      第29回日本Cell Death学会学術集会
    • Data Source
      KAKENHI-PROJECT-20K16151
  • 1.  NAKANO Hiroyasu (70276476)
    # of Collaborated Projects: 1 results
    # of Collaborated Products: 5 results
  • 2.  寺井 健太 (20616073)
    # of Collaborated Projects: 1 results
    # of Collaborated Products: 0 results
  • 3.  柳川 正隆 (70609792)
    # of Collaborated Projects: 1 results
    # of Collaborated Products: 0 results
  • 4.  OHMURAYA Masaki
    # of Collaborated Projects: 0 results
    # of Collaborated Products: 1 results

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