Takei Toshiki 武居俊樹

Researcher Number	00844771
Other IDs
Affiliation (Current)	2025: 大阪大学, 蛋白質研究所, 助教
Affiliation (based on the past Project Information) *help	2022 – 2024: 大阪大学, 蛋白質研究所, 助教 2019 – 2020: 大阪大学, 蛋白質研究所, 助教
Review Section/Research Field	Principal Investigator Basic Section 37010:Bio-related chemistry / 0501:Physical chemistry, functional solid state chemistry, organic chemistry, polymers, organic materials, biomolecular chemistry, and related fields Except Principal Investigator Basic Section 43040:Biophysics-related
Keywords	Principal Investigator タンパク質合成 / チオエステル法 / タンパク質の化学合成 / ジセレニド結合 / ナノボディ / セレノシステイン / 化学合成 / タンパク質 / ペプチド / ペプチド合成 … More / システインパースルフィド / フォールディング / プロテオミクス / 癌細胞 / HE4 / WFDC2 … More Except Principal Investigator modification / histone / IDR / EPR / ESR / 化学修飾 / エピジェネティクス / HP1 Less

細胞内タンパク質の機能制御を指向したセレノシステイン置換型ナノボディの化学合成Principal Investigator
- Principal Investigator
  
  武居俊樹
- Project Period (FY)
  2024 – 2025
- Research Category
  
  Grant-in-Aid for Early-Career Scientists
- Review Section
  
  Basic Section 37010:Bio-related chemistry
- Research Institution
  Osaka University
タンパク質の構造をとらない領域の運動性・機能の解析
- Principal Investigator
  
  末武勲
- Project Period (FY)
  2022 – 2025
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Review Section
  
  Basic Section 43040:Biophysics-related
- Research Institution
  Nakamura Gakuen College
Synthesis and analysis of cysteine persulfide-containing proteinPrincipal Investigator
- Principal Investigator
  
  Takei Toshiki
- Project Period (FY)
  2022 – 2023
- Research Category
  
  Grant-in-Aid for Early-Career Scientists
- Review Section
  
  Basic Section 37010:Bio-related chemistry
- Research Institution
  Osaka University
Analysis of cancer cell-specific WFDC2-binding proteinPrincipal Investigator
- Principal Investigator
  
  Takei Toshiki
- Project Period (FY)
  2019 – 2020
- Research Category
  
  Grant-in-Aid for Research Activity Start-up
- Review Section
  
  0501:Physical chemistry, functional solid state chemistry, organic chemistry, polymers, organic materials, biomolecular chemistry, and related fields
- Research Institution
  Osaka University

All 2024 2023 2022

All Journal Article Presentation

[Journal Article] Mutational Analysis of Substrate Recognition in Trypsin-like Protease Cocoonase: Protein Memory Induced by Alterations in Substrate-Binding Site2024
- Author(s)
  Sakata Nana、Shimamoto Shigeru、Murakami Yuri、Ashida Orika、Takei Toshiki、Miyazawa Mitsuhiro、Hidaka Yuji
- Journal Title
  
  Molecules
  
  Volume: 29 Issue: 22 Pages: 5476-5476
- DOI
  10.3390/molecules29225476
- Peer Reviewed / Open Access / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-24K22353, KAKENHI-PROJECT-24K17788, KAKENHI-PROJECT-24KJ2163
[Journal Article] Inhibitory effects of extracts from <i>Eucalyptus gunnii</i> on α-synuclein amyloid fibrils2024
- Author(s)
  So Masatomo、Ono Misaki、Oogai Shigeki、他20名、18番目
- Journal Title
  
  Bioscience, Biotechnology, and Biochemistry
  
  Volume: 88 Issue: 11 Pages: 1289-1298
- DOI
  10.1093/bbb/zbae114
- Peer Reviewed / Open Access / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-23K23464, KAKENHI-PROJECT-21K11689, KAKENHI-PROJECT-22K11895, KAKENHI-PROJECT-24K17788
[Journal Article] Unexpected diselenide metathesis in selenocysteine-substituted biologically active peptides2024
- Author(s)
  He Ying、Takei Toshiki、Moroder Luis、Hojo Hironobu
- Journal Title
  
  Organic & Biomolecular Chemistry
  
  Volume: 22 Issue: 30 Pages: 6108-6114
- DOI
  10.1039/d4ob00921e
- Peer Reviewed / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-23K23464, KAKENHI-PROJECT-24K17788
[Journal Article] Application of cysteinyl prolyl ester for the synthesis of cyclic peptides containing an RGD sequence and their biological activity measurement2024
- Author(s)
  Yamada Akina、Takei Toshiki、Kawakami Toru、Taniguchi Yukimasa、Sekiguchi Kiyotoshi、Hojo Hironobu
- Journal Title
  
  Frontiers in Chemistry
  
  Volume: 12 Pages: 1-11
- DOI
  10.3389/fchem.2024.1391678
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-23K23464, KAKENHI-PROJECT-24K17788
[Journal Article] Identification of a urinary CD276 fragment for detecting resectable pancreatic cancer using a C-terminal proteomics strategy2024
- Author(s)
  Mitsunaga Shuichi、Okumura Nobuaki、Takei Toshiki、Takao Toshifumi、Tsubouchi Hironobu、Nakata Kohei、Nakamura Masafumi、Kitahata Yuji、Motobayashi Hideki、Ikeda Masafumi、Nakazato Masamitsu
- Journal Title
  
  Scientific Reports
  
  Volume: 14 Issue: 1 Pages: 14207-14207
- DOI
  10.1038/s41598-024-65093-2
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-24K17788
[Journal Article] Dynamics of the HP1 Hinge Region with DNA Measured by Site-Directed Spin Labeling-EPR Spectroscopy2023
- Author(s)
  Suetake Isao、Sato Kazunobu、Sugishita Tomoaki、Mishima Yuichi、Takei Toshiki、Fujiwara Toshimichi、Mutoh Risa、Shinohara Akira、Takui Takeji、Miyata Makoto、Hojo Hironobu、Arata Toshiaki
- Journal Title
  
  Applied Magnetic Resonance
  
  Volume: 54 Issue: 1 Pages: 119-141
- DOI
  10.1007/s00723-022-01519-2
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-21K06117, KAKENHI-PROJECT-22K06174, KAKENHI-PROJECT-21K06046, KAKENHI-PROJECT-23K23464
[Presentation] リン酸化とヒストンペプチドによる相分離中のHP1タンパク質のアミノ酸側鎖と主鎖ダイナミクス:従来スピンラベルとTOACスピンラベルによる研究2024
- Author(s)
  末武勲、武居俊樹、佐藤和信、杉下友晃、伊藤駿、三島優一、宮田真人、藤原敏道、松木陽、北條裕信、荒田敏昭
- Organizer
  第97回日本生化学会大会
- Data Source
  KAKENHI-PROJECT-22K06174
[Presentation] Diselenide metathesis in selenocysteine-substituted biologically active peptides2024
- Author(s)
  He Ying, Toshiki Takei, Hironobu Hojo
- Organizer
  The 61st Japanese Peptide Symposium (oral)
- Data Source
  KAKENHI-PROJECT-24K17788
[Presentation] リン酸化とヒストンペプチドによる相分離中のHP1タンパク質のアミノ酸側鎖と主鎖ダイナミクス:従来スピンラベルとTOACスピンラベルによる研究2024
- Author(s)
  末武勲,武居俊樹,佐藤和信,杉下友晃,川上徹,伊藤駿,村岡浩平,三島優一,宮田真人,工位武治,藤原敏道,松木陽,北條裕信,荒田敏昭
- Organizer
  電子スピンサイエンス学会　SEST
- Data Source
  KAKENHI-PROJECT-22K06174
[Presentation] 相分離中のHP1タンパク質のアミノ酸側鎖と主鎖ダイナミクスに与えるＮ末端リン酸化とヒストンペプチドの効果:従来スピンラベルとTOACスピンラベルによる研究2024
- Author(s)
  末武勲、武居俊樹、佐藤和信、杉下友晃、三島優一、宮田真人、藤原敏道、松木陽、北條裕信、荒田敏昭
- Organizer
  第47回日本分子生物学会
- Data Source
  KAKENHI-PROJECT-22K06174
[Presentation] スピンラベルESRによるヘテロクロマチンタンパク質HP1の動的構造研究：DNA・メチルヒストンペプチド・リン酸化・相分離の効果2024
- Author(s)
  Isao SUETAKE, Toshiki TAKEI, Tomoaki SUGISHITA, Shun ITO, Kazunobu SATO, Yuichi MISHIMA, Yoh MATSUKI, Makoto MIYATA, Hironobu HOJO, Toshiaki ARATA
- Organizer
  第17回　日本エピジェネティクス研究会
- Data Source
  KAKENHI-PROJECT-22K06174
[Presentation] Total synthesis and analysis of deamidated β2-microglobulin2024
- Author(s)
  Ryuji Kawakami, Toshiki Takei, Toshifumi Takao, Hironobu Hojo
- Organizer
  The 61st Japanese Peptide Symposium (poster)
- Data Source
  KAKENHI-PROJECT-24K17788
[Presentation] Phosphorylation and histone peptides reduce main- but not side-chain dynamics of N-terminal intrinsically disordered region of HP1 during phase separation, as studied by conventional and TOAC spin labels2024
- Author(s)
  Isao SUETAKE, Toshiki TAKEI, Tomoaki SUGISHITA,　Shun ITO, Kazunobu SATO, Yuichi MISHIMA, Kohei MURAOKA, Toru KAWAKAMI, Yoh MATSUKI, Toshimichi FUJIWARA, Takeji TAKUIi, Makoto MIYATA, Hironobu HOJO, Toshiaki ARATA
- Organizer
  IUPAB2024
- Data Source
  KAKENHI-PROJECT-22K06174
[Presentation] Dynamics of the HP1 Hinge Region with DNA Measured by Site-directed Spin Labeling-EPR Spectroscopy2023
- Author(s)
  Suetake I, Sato K, Sugishita T, Mishima Y, Takei T, Fujiwara T, Mutoh R, Shinohara A, Takui T, Miyata M, Hojo H, Arata T
- Organizer
  第23回日本蛋白質科学会年会
- Data Source
  KAKENHI-PROJECT-22K06174
[Presentation] ANALYSIS OF THE EFFECT OF PHOSPHORYLATION ON HP1α DYNAMICS BY ESR SPECTROSCOPY2023
- Author(s)
  Takei T, Muraoka K, Kawakami T, Arata T, Suetake I, Hojo H
- Organizer
  第60回ペプチド討論会.
- Data Source
  KAKENHI-PROJECT-22K06174
[Presentation] ESRによるHP1ヒンジのダイナミクスとDNA結合2022
- Author(s)
  末武勲、佐藤和信、川上徹、杉下友晃、武藤梨沙、三島優一、工位武治、藤原敏道、武居俊樹、北條裕信、宮田真人、荒田敏明
- Organizer
  第45回日本分子生物学会年会
- Data Source
  KAKENHI-PROJECT-22K06174

1. 末武勲 (80304054)

# of Collaborated Projects: 1 results

# of Collaborated Products: 8 results
2. 北條裕信 (00209214)

# of Collaborated Projects: 1 results

# of Collaborated Products: 10 results
3. 荒田敏昭 (70151165)

# of Collaborated Projects: 1 results

# of Collaborated Products: 8 results
4. 島本茂

# of Collaborated Projects: 0 results

# of Collaborated Products: 1 results
5. 武藤梨沙

# of Collaborated Projects: 0 results

# of Collaborated Products: 1 results

Takei Toshiki 武居 俊樹

Research Projects

Research Products

Co-Researchers

細胞内タンパク質の機能制御を指向したセレノシステイン置換型ナノボディの化学合成Principal Investigator

Principal Investigator

Project Period (FY)

Research Category

Review Section

Research Institution

タンパク質の構造をとらない領域 の運動性・機能の解析

Principal Investigator

Project Period (FY)

Research Category

Review Section

Research Institution

Synthesis and analysis of cysteine persulfide-containing proteinPrincipal Investigator

Principal Investigator

Project Period (FY)

Research Category

Review Section

Research Institution

Analysis of cancer cell-specific WFDC2-binding proteinPrincipal Investigator

Principal Investigator

Project Period (FY)

Research Category

Review Section

Research Institution

[Journal Article] Mutational Analysis of Substrate Recognition in Trypsin-like Protease Cocoonase: Protein Memory Induced by Alterations in Substrate-Binding Site2024

Author(s)

Journal Title

DOI

Data Source

[Journal Article] Inhibitory effects of extracts from <i>Eucalyptus gunnii</i> on α-synuclein amyloid fibrils2024

Author(s)

Journal Title

DOI

Data Source

[Journal Article] Unexpected diselenide metathesis in selenocysteine-substituted biologically active peptides2024

Author(s)

Journal Title

DOI

Data Source

[Journal Article] Application of cysteinyl prolyl ester for the synthesis of cyclic peptides containing an RGD sequence and their biological activity measurement2024

Author(s)

Journal Title

DOI

Data Source

[Journal Article] Identification of a urinary CD276 fragment for detecting resectable pancreatic cancer using a C-terminal proteomics strategy2024

Author(s)

Journal Title

DOI

Data Source

[Journal Article] Dynamics of the HP1 Hinge Region with DNA Measured by Site-Directed Spin Labeling-EPR Spectroscopy2023

Author(s)

Journal Title

DOI

Data Source

[Presentation] リン酸化とヒストンペプチドによる相分離中のHP1タンパク質のアミノ酸側鎖と主鎖ダイナミクス:従来スピンラベルとTOACスピンラベルによる研究2024

Author(s)

Organizer

Data Source

[Presentation] Diselenide metathesis in selenocysteine-substituted biologically active peptides2024

Author(s)

Organizer

Data Source

[Presentation] リン酸化とヒストンペプチドによる相分離中のHP1タンパク質のアミノ酸側鎖と主鎖ダイナミクス:従来スピンラベルとTOACスピンラベルによる研究2024

Author(s)

Organizer

Data Source

[Presentation] 相分離中のHP1タンパク質のアミノ酸側鎖と主鎖ダイナミクスに与えるＮ末端リン酸化とヒストンペプチドの効果:従来スピンラベルとTOACスピンラベルによる研究2024

Author(s)

Organizer

Data Source

[Presentation] スピンラベルESRによるヘテロクロマチンタンパク質HP1の動的構造研究：DNA・メチルヒストンペプチド・リン酸化・相分離の効果2024

Author(s)

Organizer

Data Source

[Presentation] Total synthesis and analysis of deamidated β2-microglobulin2024

Author(s)

Takei Toshiki 武居俊樹

タンパク質の構造をとらない領域の運動性・機能の解析