YASUDA Tadahito 安田忠仁

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Yasuda Tadahito 安田忠仁

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Researcher Number	00867947
Other IDs
Affiliation (Current)	2025: 公益財団法人がん研究会, がん研究所発がん研究部, 客員研究員
Affiliation (based on the past Project Information) *help	2023 – 2024: 公益財団法人がん研究会, がん研究所発がん研究部, 客員研究員 2021 – 2023: 熊本大学, 大学院生命科学研究部(医), 特定研究員 2020: 熊本大学, 病院, 医員
Review Section/Research Field	Principal Investigator Basic Section 55010:General surgery and pediatric surgery-related Except Principal Investigator Medium-sized Section 55:Surgery of the organs maintaining homeostasis and related fields / Basic Section 55020:Digestive surgery-related / Basic Section 55010:General surgery and pediatric surgery-related
Keywords	Principal Investigator CAFs / 胃癌 / 線維化 / 遠隔臓器連関 / 血小板 / PDGF / 腫瘍間質 / 胃がん / JAK-STAT阻害剤 / 細胞老化 / 腹膜播種 / EZH2 / 腫瘍微小環境 … More Except Principal Investigator … More CAFs / 空間的遺伝子発現解析 / 胃がん / シングルセル解析 / リプログラミング / ADC / 腫瘍間質 / オープンクロマチン領域 / 単一核マルチオーム解析 / エピゲノム / 乳酸 / LDHA / 代謝リモデリング / 膵癌 / ストローマ / 多様性 / 間質 Less

ストローマル・リプログラミングを軸としたがん治療戦略の開発
- Principal Investigator
  
  石本崇胤
- Project Period (FY)
  2024 – 2026
- Research Category
  
  Fund for the Promotion of Joint International Research (International Collaborative Research)
- Review Section
  
  Medium-sized Section 55:Surgery of the organs maintaining homeostasis and related fields
- Research Institution
  Japanese Foundation for Cancer Research
遠隔臓器コミュニケーションによるスキルス胃癌線維化メカニズムの解明Principal Investigator
- Principal Investigator
  
  安田忠仁
- Project Period (FY)
  2023 – 2025
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Review Section
  
  Basic Section 55010:General surgery and pediatric surgery-related
- Research Institution
  Japanese Foundation for Cancer Research
単一核マルチオーム解析を用いた胃がん間質不均一性の解明
- Principal Investigator
  
  内原智幸
- Project Period (FY)
  2023 – 2025
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Review Section
  
  Basic Section 55020:Digestive surgery-related
- Research Institution
  Japanese Foundation for Cancer Research
がんーストローマ代謝物クロストークによる膵癌進展メカニズムの解明
- Principal Investigator
  
  北村文優
- Project Period (FY)
  2022 – 2024
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Review Section
  
  Basic Section 55010:General surgery and pediatric surgery-related
- Research Institution
  Kumamoto University
Elucidation of diversity and therapeutic target in scirrhous gastric cancer stroma
- Principal Investigator
  
  ISHIMOTO Takatsugu
- Project Period (FY)
  2021 – 2023
- Research Category
  
  Fund for the Promotion of Joint International Research (Fostering Joint International Research (B))
- Review Section
  
  Medium-sized Section 55:Surgery of the organs maintaining homeostasis and related fields
- Research Institution
  Kumamoto University
Identification of molecular mechanism underlying peritoneal metastasis progression by tumor stromal cells.Principal Investigator
- Principal Investigator
  
  Yasuda Tadahito
- Project Period (FY)
  2020 – 2022
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Review Section
  
  Basic Section 55010:General surgery and pediatric surgery-related
- Research Institution
  Kumamoto University

All 2024 2023 2022 2021 2020

All Journal Article Presentation

[Journal Article] Mesothelial cells with mesenchymal features enhance peritoneal dissemination by forming a protumorigenic microenvironment2024
- Author(s)
  Yonemura A、Semba T、Zhang J、Fan Y、Yasuda-Yoshihara N、Wang H、Uchihara T、Yasuda T、Nishimura A、Fu L、Hu X、Wei F、Kitamura F、Akiyama T、Yamashita K、Eto K、Iwagami S、Iwatsuki M、Miyamoto Y、Matsusaki K、Yamasaki J、Nagano O、Saya H、Song S、Tan P、Baba H、Ajani Jaffer A.、Ishimoto T
- Journal Title
  
  Cell Reports
  
  Volume: 43 Issue: 1 Pages: 113613-113613
- DOI
  10.1016/j.celrep.2023.113613
- Peer Reviewed / Open Access / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-23K14572, KAKENHI-PROJECT-23K14621, KAKENHI-PROJECT-23K08051, KAKENHI-PROJECT-23K08113, KAKENHI-PROJECT-22K20836, KAKENHI-PROJECT-21KK0153, KAKENHI-PROJECT-23H00410, KAKENHI-PROJECT-23K27689
[Journal Article] RAC1-mediated integrin alpha-6 expression in E-cadherin-deficient gastric cancer cells promotes interactions with the stroma and peritoneal dissemination2024
- Author(s)
  Zhang Jun、Fu Lingfeng、Wang Huaitao、Yonemura Atsuko、Semba Takashi、Yasuda-Yoshihara Noriko、Nishimura Akiho、Tajiri Takuya、Tong Yilin、Yasuda Tadahito、Uchihara Tomoyuki、Yamazaki Masaya、Okamoto Yuya、Yamasaki Juntaro、Nagano Osamu、Baba Hideo、Ishimoto Takatsugu
- Journal Title
  
  Cancer Letters
  
  Volume: 591 Pages: 216901-216901
- DOI
  10.1016/j.canlet.2024.216901
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-23K14572, KAKENHI-PROJECT-22K20836, KAKENHI-PROJECT-21KK0153, KAKENHI-PROJECT-23K27689
[Journal Article] Downregulation of 15-PGDH enhances MASH-HCC development via fatty acid-induced T-cell exhaustion2023
- Author(s)
  Hu X、Yasuda T、Yasuda-Yosihara N、Yonemura A、Umemoto T、Nakachi Y、Yamashita K、Semba T、Arima K、Uchihara T、Nishimura A、Bu L、Fu Li、Wei F、Zhang J、Tong Y、Wang H、Iwamoto K、Fukuda T、Nakagawa H、Taniguchi K、Miyamoto Y、Baba H、Ishimoto T
- Journal Title
  
  JHEP Reports
  
  Volume: 5 Issue: 12 Pages: 100892-100892
- DOI
  10.1016/j.jhepr.2023.100892
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-23K08051, KAKENHI-PROJECT-21K08686, KAKENHI-PROJECT-21KK0153, KAKENHI-PROJECT-20H03758, KAKENHI-PROJECT-22H04925, KAKENHI-PROJECT-23K27463, KAKENHI-PROJECT-23K27669
[Journal Article] IL-1β derived from mixed-polarized macrophages activates fibroblasts and synergistically forms a cancer-promoting microenvironment2023
- Author(s)
  Zhang Jun、Fu Lingfeng、Yasuda-Yoshihara Noriko、Yonemura Atsuko、Wei Feng、Bu Luke、Hu Xichen、Akiyama Takahiko、Kitamura Fumimasa、Yasuda Tadahito、Semba Takashi、Uchihara Tomoyuki、Itoyama Rumi、Yamashita Kohei、Eto Kojiro、Iwagami Shiro、Yashiro Masakazu、Komohara Yoshihiro、Baba Hideo、Ishimoto Takatsugu
- Journal Title
  
  Gastric Cancer
  
  Volume: 26 Issue: 2 Pages: 187-202
- DOI
  10.1007/s10120-022-01352-3
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-23K08051, KAKENHI-PROJECT-21KK0153, KAKENHI-PROJECT-23K27463
[Journal Article] Cancer-associated fibroblasts reuse cancer-derived lactate to maintain a fibrotic and immunosuppressive microenvironment in pancreatic cancer2023
- Author(s)
  Kitamura F、Semba T、Yasuda-Yoshihara N、Yamada K、Nishimura A、Yamasaki J、Nagano O、Yasuda T、Yonemura A、Tong Y、Wang H、Akiyama T、Matsumura K、Uemura N、Itoyama R、Bu L、Fu L、Hu X、Wei F、Mima K、Imai K、Hayashi H、Yamashita Y、Miyamoto Y、Baba H、Ishimoto T
- Journal Title
  
  JCI Insight
  
  Volume: 8 Issue: 20
- DOI
  10.1172/jci.insight.163022
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-23K14572, KAKENHI-PROJECT-23K14621, KAKENHI-PROJECT-22K08756, KAKENHI-PROJECT-23K08051, KAKENHI-PROJECT-22K16537, KAKENHI-PROJECT-22K20836, KAKENHI-PROJECT-21KK0153, KAKENHI-PROJECT-23K27463, KAKENHI-PROJECT-23K27689
[Journal Article] A novel tdTomato transgenic mouse model to visualize FAP‐positive cancer‐associated fibroblasts2023
- Author(s)
  Wei F , Uchihara T , Yonemura A , Yasuda-Yoshihara N , Yasuda T , Semba T , Fukuda M , Akiyama T , Kitamura F , Kariya R , Yamasaki J , Aihara K , Yamashita K , Nagano O , Okada S , Baba H , Ishimoto T
- Journal Title
  
  The FEBS Journal
  
  Volume: - Issue: 10 Pages: 2604-2615
- DOI
  10.1111/febs.16712
- Peer Reviewed / Open Access / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-22K20836, KAKENHI-PROJECT-20K08961, KAKENHI-PROJECT-21K19535, KAKENHI-PROJECT-23K14621, KAKENHI-PROJECT-23K06745, KAKENHI-PROJECT-23K08051, KAKENHI-PROJECT-21KK0153, KAKENHI-PROJECT-23K27463
[Journal Article] LINE-1 hypomethylation, increased retrotransposition and tumor-specific insertion in upper gastrointestinal cancer2023
- Author(s)
  Baba Y, Yasuda N, Bundo M, Nakachi Y, Ueda J, Ishimoto T, Iwatsuki M, Miyamoto Y, Yoshida N, Oshiumi H, Iwamoto K, Baba H.
- Journal Title
  
  Cancer Science
  
  Volume: 115 Issue: 1 Pages: 247-256
- DOI
  10.1111/cas.16007
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-21KK0153, KAKENHI-PROJECT-23K27640
[Journal Article] Cellular senescence in the tumor microenvironment and context‐specific cancer treatment strategies2023
- Author(s)
  Yasuda Tadahito、Baba Hideo、Ishimoto Takatsugu
- Journal Title
  
  The FEBS Journal
  
  Volume: 290 Issue: 5 Pages: 1290-1302
- DOI
  10.1111/febs.16231
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-20K08985, KAKENHI-PROJECT-23K08051
[Journal Article] Detection of senescent cells in malignant ascites using mass cytometry and therapeutic strategies focused on cellular senescence2022
- Author(s)
  安田忠仁、石本崇胤
- Journal Title
  
  Cytometry Research
  
  Volume: 32 Issue: 1 Pages: 27-32
- DOI
  10.18947/cytometryresearch.32.1_27
- ISSN
  0916-6920, 2424-0664
- Year and Date
  2022-07-13
- Language
  Japanese
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-20K08985
[Journal Article] Tumor microenvironmental 15‐PGDH depletion promotes fibrotic tumor formation and angiogenesis in pancreatic cancer2022
- Author(s)
  Bu L, Yonemura A, Yasuda-Yoshihara N, Uchihara T, Ismagulov G, Takasugi S, Yasuda T, Okamoto Y, Kitamura F, Akiyama T, Arima K, Itoyama R, Zhang J, Fu L, Hu X, Wei, F, Arima Y, Moroishi T, Nishiyama K, Sheng G, Mukunoki T, Otani J, Baba H, Ishimoto T
- Journal Title
  
  Cancer Science
  
  Volume: 113 Issue: 10 Pages: 3579-3592
- DOI
  10.1111/cas.15495
- Peer Reviewed / Open Access / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-21KK0153, KAKENHI-PROJECT-20H03531, KAKENHI-PROJECT-21H02490, KAKENHI-PROJECT-20K09038, KAKENHI-PROJECT-21K19535
[Journal Article] Single-Cell Atlas of Lineage States, Tumor Microenvironment, and Subtype-Specific Expression Programs in Gastric Cancer2022
- Author(s)
  Kumar V, Ramnarayanan K, Sundar R, Padmanbahan N, Srivastava S, Koiwa M, Yasuda T, Koh V, Huang K, Tay S, Ho S, Tan A, Ishimoto T
- Journal Title
  
  Cancer Discovery
  
  Volume: 12 Issue: 3 Pages: 670-691
- DOI
  10.1158/2159-8290.cd-21-0683
- Peer Reviewed / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-21KK0153, KAKENHI-PROJECT-20H03531, KAKENHI-PROJECT-21K19535
[Journal Article] Stromal reprogramming through dual PDGFRα/β blockade boosts the efficacy of anti-PD-1 immunotherapy in fibrotic tumors.2022
- Author(s)
  T. Akiyama, T. Yasuda, T. Uchihara, N. Yasuda-Yoshihara, BJY. Tan, A. Yonemura, T. Semba, J. Yamasaki, Y. Komohara, K. Ohnishi, F. Wei, L. Fu, J. Zhang, F. Kitamura, K. Yamashita, K. Eto, S. Iwagami, H. Tsukamoto, T. Umemoto, M. Masuda, O. Nagano, Y. Satou, H. Saya, P. Tan, H. Baba, T. Ishimoto
- Journal Title
  
  Cancer Res.
  
  Volume: 83 Issue: 5 Pages: 753-770
- DOI
  10.1158/0008-5472.can-22-1890
- Peer Reviewed / Open Access / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-21K07370, KAKENHI-PROJECT-22K20836, KAKENHI-PROJECT-20H00518, KAKENHI-PROJECT-20H03531, KAKENHI-PROJECT-21H02788, KAKENHI-PROJECT-20K07690, KAKENHI-PROJECT-21K19416, KAKENHI-PROJECT-21K19535, KAKENHI-PROJECT-23K08051, KAKENHI-PROJECT-21KK0153, KAKENHI-PROJECT-23K27463
[Journal Article] Metabolic shift to serine biosynthesis through 3-PG accumulation and PHGDH induction promotes tumor growth in pancreatic cancer2021
- Author(s)
  Itoyama R, Yasuda-Yoshihara N, Kitamura F, Yasuda T, Bu L, Yonemura A, Uchihara T, Arima K, Hu X, Jun Z, Okamoto Y, Akiyama T, Yamashita K, Nakao Y, Yusa T, Kitano Y, Higashi T, Miyata T, Imai K, Hayashi H, Yamashita Y, Mikawa T, Kondoh H, Baba H, Ishimoto T
- Journal Title
  
  Cancer Letters
  
  Volume: 523 Pages: 29-42
- DOI
  10.1016/j.canlet.2021.09.007
- Peer Reviewed / Open Access / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-19K07887, KAKENHI-PROJECT-20K16418, KAKENHI-PROJECT-20H03531, KAKENHI-PROJECT-20K09038, KAKENHI-PROJECT-21K19535, KAKENHI-PROJECT-21K16384, KAKENHI-PROJECT-21KK0153, KAKENHI-PROJECT-20K20658
[Journal Article] Inflammation-driven senescence-associated secretory phenotype in cancer-associated fibroblasts enhances peritoneal dissemination2021
- Author(s)
  Yasuda T, Koiwa M, Yonemura A, Miyake K, Kariya R, Kubota S, Yokomizo-Nakano T, Yasuda-Yoshihara N, Uchihara T, Itoyama R, Bu L, Fu L, Arima K, Izumi D, Iwagami S, Eto K, Iwatsuki M, Baba Y, Yoshida N, Ohguchi H, Okada S, Matsusaki K, Sashida G, Takahashi A, Tan P, Baba H, Ishimoto T.
- Journal Title
  
  Cell Reports
  
  Volume: 34 Issue: 8 Pages: 108779-108779
- DOI
  10.1016/j.celrep.2021.108779
- Peer Reviewed / Open Access / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-18K08543, KAKENHI-PROJECT-19K16749, KAKENHI-PROJECT-19H03507, KAKENHI-PROJECT-20H03531, KAKENHI-PROJECT-20K08985, KAKENHI-PROJECT-21K19535, KAKENHI-PROJECT-21K16384, KAKENHI-PROJECT-21KK0153
[Journal Article] Conflicting metabolic alterations in cancer stem cells and regulation by the stromal niche2021
- Author(s)
  Yasuda T, I Ishimoto T, Baba H
- Journal Title
  
  Regenerative Therapy
  
  Volume: 17 Pages: 8-12
- DOI
  10.1016/j.reth.2021.01.005
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-20H03531, KAKENHI-PROJECT-21K19535, KAKENHI-PROJECT-21KK0153
[Journal Article] Protocol to establish cancer-associated fibroblasts from surgically resected tissues and generate senescent fibroblasts2021
- Author(s)
  Yasuda T, Koiwa M, Yonemura A, Akiyama T, Baba H, Ishimoto T
- Journal Title
  
  STAR Protocols
  
  Volume: 2 Issue: 2 Pages: 100553-100553
- DOI
  10.1016/j.xpro.2021.100553
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-20H03531, KAKENHI-PROJECT-20K08985, KAKENHI-PROJECT-21K19535, KAKENHI-PROJECT-21KK0153
[Journal Article] Extracellular Vesicles from Cancer-Associated Fibroblasts Containing Annexin A6 Induces FAK-YAP Activation by Stabilizing β1 Integrin, Enhancing Drug Resistance2020
- Author(s)
  Uchihara T, Miyake K, Yonemura A, Komohara Y, Itoyama R, Koiwa M, Yasuda T, Arima K, Harada K, Eto K, Hayashi H, Iwatsuki M, Iwagami S, Baba Y, Yoshida N, Yashiro M, Masuda M, Ajani Jaffer A, Tan Patrick, Baba H, Ishimoto T
- Journal Title
  
  Cancer Research
  
  Volume: 80 Issue: 16 Pages: 3222-3235
- DOI
  10.1158/0008-5472.can-19-3803
- Peer Reviewed / Open Access / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-19K09177, KAKENHI-PROJECT-20K07690, KAKENHI-PROJECT-20K08985, KAKENHI-PROJECT-18H02694, KAKENHI-PROJECT-20H03531, KAKENHI-PROJECT-18K08543, KAKENHI-PROJECT-19K16720, KAKENHI-PROJECT-19K16749, KAKENHI-PROJECT-18H02883
[Journal Article] Functional diversity of cancer‐associated fibroblasts in modulating drug resistance2020
- Author(s)
  Bu Luke、Baba Hideo、Yasuda Tadahito、Uchihara Tomoyuki、Ishimoto Takatsugu
- Journal Title
  
  Cancer Science
  
  Volume: 111 Issue: 10 Pages: 3468-3477
- DOI
  10.1111/cas.14578
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-20K08985, KAKENHI-PROJECT-20H03531
[Presentation] 腹膜播種形成を促進するがん性腹水中老化細胞の意義2022
- Author(s)
  安田忠仁
- Organizer
  第81回日本癌学会
- Invited
- Data Source
  KAKENHI-PROJECT-20K08985
[Presentation] Senescent-CAFs in malignant ascites enhance peritoneal tumor formation2022
- Author(s)
  Tadahito Yasuda, Mayu Koiwa, Hideo Baba, Takatsugu Ishimoto
- Organizer
  IGCC2022
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-20K08985
[Presentation] 癌性腹水中SASP-CAFsによる腹膜播種促進メカニズムの解明2021
- Author(s)
  安田忠仁、小岩麻由、馬場秀夫、石本崇胤
- Organizer
  第29回JDDW
- Data Source
  KAKENHI-PROJECT-20K08985
[Presentation] がん性腹水中senescent-CAFsによる腹膜播種促進メカニズムの解明2021
- Author(s)
  安田忠仁、小岩麻由、馬場秀夫、石本崇胤
- Organizer
  第29回日本癌病態治療研究会
- Data Source
  KAKENHI-PROJECT-20K08985
[Presentation] 癌性腹水中Senescent-CAFsによる腹膜播種促進メカニズムの解明2021
- Author(s)
  安田忠仁、小岩麻由、馬場秀夫、石本崇胤
- Organizer
  第93回日本胃癌学会
- Data Source
  KAKENHI-PROJECT-20K08985
[Presentation] 腫瘍間質細胞によって促進される胃癌腹膜播種進展メカニズムの解明2021
- Author(s)
  安田忠仁、小岩麻由、馬場秀夫、石本崇胤
- Organizer
  第32回日本消化器癌発生学会総会
- Invited
- Data Source
  KAKENHI-PROJECT-20K08985
[Presentation] 全身性炎症を背景とする病態を制御し、難治癌の克服を目指すトランスレーショナル研究2021
- Author(s)
  安田忠仁、小岩麻由、米村敦子、ブルコ、馬場秀夫、石本崇胤
- Organizer
  第80回日本癌学会
- Data Source
  KAKENHI-PROJECT-20K08985
[Presentation] 胃癌由来CAFsの老化と腹膜播種進展機序の解明2020
- Author(s)
  安田忠仁、石本崇胤、小岩麻由、米村敦子、三宅慧輔、内原智幸、江藤弘二郎、岩上志朗、馬場祥史、岩槻政晃、吉田直矢、馬場秀夫
- Organizer
  第120回日本外科学会学術集会
- Data Source
  KAKENHI-PROJECT-20K08985
[Presentation] Gastric cancer CAFs maintain SASP through epigenetic histone modification and enhance peritoneal dissemination2020
- Author(s)
  Tadahito Yasuda, Mayu Koiwa, Atsuko Yonemura, Keisuke Miyake, Luke Bu, Hideo Baba, and Takatsugu Ishimoto
- Organizer
  第79回日本癌学会学術総会
- Data Source
  KAKENHI-PROJECT-20K08985

1. ISHIMOTO Takatsugu (00594889)

# of Collaborated Projects: 6 results

# of Collaborated Products: 19 results
2. 内原智幸 (60835172)

# of Collaborated Projects: 2 results

# of Collaborated Products: 1 results
3. 三宅慧輔 (10814759)

# of Collaborated Projects: 1 results

# of Collaborated Products: 3 results
4. 北村文優 (90897068)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
5. 千場隆 (30897682)

# of Collaborated Projects: 1 results

# of Collaborated Products: 2 results
6. 付凌峰 (40973730)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
7. 林洋光

# of Collaborated Projects: 0 results

# of Collaborated Products: 1 results
8. 三河拓己

# of Collaborated Projects: 0 results

# of Collaborated Products: 1 results
9. 有馬浩太

# of Collaborated Projects: 0 results

# of Collaborated Products: 1 results
10. 泉大輔

# of Collaborated Projects: 0 results

# of Collaborated Products: 1 results
11. 大西紘二

# of Collaborated Projects: 0 results

# of Collaborated Products: 1 results
12. 須田年生

# of Collaborated Projects: 0 results

# of Collaborated Products: 2 results
13. 山崎淳太郎

# of Collaborated Projects: 0 results

# of Collaborated Products: 4 results

YASUDA Tadahito 安田 忠仁

Yasuda Tadahito 安田 忠仁

Research Projects

Research Products

Co-Researchers

ストローマル・リプログラミングを軸としたがん治療戦略の開発

Principal Investigator

Project Period (FY)

Research Category

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Research Institution

遠隔臓器コミュニケーションによるスキルス胃癌線維化メカニズムの解明Principal Investigator

Principal Investigator

Project Period (FY)

Research Category

Review Section

Research Institution

単一核マルチオーム解析を用いた胃がん間質不均一性の解明

Principal Investigator

Project Period (FY)

Research Category

Review Section

Research Institution

がんーストローマ代謝物クロストークによる膵癌進展メカニズムの解明

Principal Investigator

Project Period (FY)

Research Category

Review Section

Research Institution

Elucidation of diversity and therapeutic target in scirrhous gastric cancer stroma

Principal Investigator

Project Period (FY)

Research Category

Review Section

Research Institution

Identification of molecular mechanism underlying peritoneal metastasis progression by tumor stromal cells.Principal Investigator

Principal Investigator

Project Period (FY)

Research Category

Review Section

Research Institution

[Journal Article] Mesothelial cells with mesenchymal features enhance peritoneal dissemination by forming a protumorigenic microenvironment2024

Author(s)

Journal Title

DOI

Data Source

[Journal Article] RAC1-mediated integrin alpha-6 expression in E-cadherin-deficient gastric cancer cells promotes interactions with the stroma and peritoneal dissemination2024

Author(s)

Journal Title

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[Journal Article] Downregulation of 15-PGDH enhances MASH-HCC development via fatty acid-induced T-cell exhaustion2023

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[Journal Article] IL-1β derived from mixed-polarized macrophages activates fibroblasts and synergistically forms a cancer-promoting microenvironment2023

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[Journal Article] Cancer-associated fibroblasts reuse cancer-derived lactate to maintain a fibrotic and immunosuppressive microenvironment in pancreatic cancer2023

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[Journal Article] A novel tdTomato transgenic mouse model to visualize FAP‐positive cancer‐associated fibroblasts2023

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[Journal Article] LINE-1 hypomethylation, increased retrotransposition and tumor-specific insertion in upper gastrointestinal cancer2023

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[Journal Article] Cellular senescence in the tumor microenvironment and context‐specific cancer treatment strategies2023

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YASUDA Tadahito 安田忠仁

Yasuda Tadahito 安田忠仁