Itohara Kotaro 糸原光太郎

Researcher Number	00870445
Other IDs
Affiliation (Current)	2025: 神戸大学, 医学部附属病院, 助教
Affiliation (based on the past Project Information) *help	2022 – 2023: 神戸大学, 医学部附属病院, 特命助教 2021: 京都大学, 医学研究科, 助教
Review Section/Research Field	Principal Investigator Basic Section 47060:Clinical pharmacy-related
Keywords	Principal Investigator 免疫抑制剤 / 薬物動態 / ファーマコメトリクス / 肺移植 / 肝移植 / 相互作用 / イトラコナゾール / 臓器移植 / エベロリムス / タクロリムス / 母集団解析

Research Projects
(1 results)
Research Products
(11 results)

The construction of design for personalized dosing for immunosuppressants using pharmacometricsPrincipal Investigator
- Principal Investigator
  
  Itohara Kotaro
- Project Period (FY)
  2021 – 2023
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Review Section
  
  Basic Section 47060:Clinical pharmacy-related
- Research Institution
  Kobe University
  Kyoto University

All 2024 2023 2022 2021

All Journal Article Presentation

[Journal Article] Population pharmacokinetics of everolimus in renal transplant recipients receiving long-term multiple immunosuppressive therapy2024
- Author(s)
  Sakaue Tomoyuki、Yamamoto Kazuhiro、Itohara Kotaro、Kitahiro Yumi、Endo Takahito、Yokoyama Naoki、Ishimura Takeshi、Omura Tomohiro、Yano Ikuko
- Journal Title
  
  Drug Metabolism and Pharmacokinetics
  
  Volume: 56 Pages: 101009-101009
- DOI
  10.1016/j.dmpk.2024.101009
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-21K06711
[Journal Article] A model-based pharmacokinetic assessment of drug-drug interaction between tacrolimus and nirmatrelvir/ritonavir in a kidney transplant patient with COVID-192023
- Author(s)
  Tomida Takeshi、Itohara Kotaro、Yamamoto Kazuhiro、Kimura Takeshi、Fujita Kohei、Uda Atsushi、Kitahiro Yumi、Yokoyama Naoki、Hyodo Yoji、Omura Tomohiro、Yano Ikuko
- Journal Title
  
  Drug Metabolism and Pharmacokinetics
  
  Volume: 53 Pages: 100529-100529
- DOI
  10.1016/j.dmpk.2023.100529
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-21K06711
[Journal Article] Association between time in therapeutic range of tacrolimus blood concentration and acute rejection within the first three months after lung transplantation2022
- Author(s)
  Yoshiki Katada, Shunsaku Nakagawa, Kotaro Itohara, Takuya Suzuki, Ryota Kato, Hiroki Endo, Mitsuhiro Sugimoto, Atsushi Yonezawa, Takayuki Nakagawa, Akihiro Ohsumi, Daisuke Nakajima, Hiroshi Date, Tomohiro Terada
- Journal Title
  
  Journal of Pharmaceutical Health Care and Sciences
  
  Volume: 8 Issue: 1 Pages: 25-25
- DOI
  10.1186/s40780-022-00256-9
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-21K06711, KAKENHI-PROJECT-22H04309
[Journal Article] Population pharmacokinetics of everolimus in adult liver transplant patients: Comparison to tacrolimus disposition and extrapolation to pediatrics2022
- Author(s)
  Kotaro Itohara, Ikuko Yano, Shunsaku Nakagawa, Mitsuhiro Sugimoto, Machiko Hirai, Atsushi Yonezawa, Satoshi Imai, Takayuki Nakagawa, Daiki Hira, Takashi Ito, Koichiro Hata, Etsuro Hatano, Tomohiro Terada, Kazuo Matsubara
- Journal Title
  
  Clinical and Translational Science
  
  Volume: 15 Issue: 11 Pages: 2652-2662
- DOI
  10.1111/cts.13389
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-21K06711, KAKENHI-PROJECT-22K06697
[Presentation] A model-based pharmacokinetic analysis of drug-drug interaction between nirmatrelvir/ritonavir and tacrolimus2023
- Author(s)
  Itohara K, Tomida T, Yamamoto K, Kimura T, Fujita K, Uda A, Kitahiro Y, Yokoyama N, Hyodo Y, Omura T, Yano I
- Organizer
  The 21st International Congress of Therapeutic Drug Monitoring & Clinical Toxicology (IATDMCT 2023)
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-21K06711
[Presentation] 生理学的薬物動態モデルを活用したタクロリムスの薬物動態予測2023
- Author(s)
  糸原光太郎
- Organizer
  第44回日本臨床薬理学会総会
- Data Source
  KAKENHI-PROJECT-21K06711
[Presentation] 肺移植患者におけるイトラコナゾール併用に着目したタクロリムスの母集団薬物動態解析2023
- Author(s)
  高橋連，糸原光太郎，中川俊作，片田佳希，杉本充弘，梅村圭祐，松村勝之、今吉菜月，勝部友里恵，平大樹，今井哲司，米澤淳，中川貴之，田中里奈，大角明宏，中島大輔，長尾美紀，伊達洋至，寺田智祐
- Organizer
  第39回日本TDM学会・学術大会
- Data Source
  KAKENHI-PROJECT-21K06711
[Presentation] ニルマトレルビル/リトナビル併用時にタクロリムス濃度の異常高値を認めた腎移植症例2023
- Author(s)
  冨田猛，木村丈司，山本和宏，宇田篤史，藤田浩平，荻原孝史，糸原光太郎，北廣優実，大村友博，矢野育子
- Organizer
  第25回日本医薬品情報学会総会・学術大会
- Data Source
  KAKENHI-PROJECT-21K06711
[Presentation] Population pharmacokinetic analysis and dosing optimization of tacrolimus in lung transplant recipients with itraconazole2023
- Author(s)
  Takahashi R, Itohara K, Nakagawa S, Katada Y, Sugimoto M, Umemura K, Matsumura K, Shigetsura Y, Imayoshi N, Katsube Y, Hira D, Tsuda M, Imai S, Yonezawa A, Nakagawa T, Tanaka S, Ohsumi A, Nakajima D, Nagao M, Date H, Terada T
- Organizer
  第33回日本医療薬学会年会
- Data Source
  KAKENHI-PROJECT-21K06711
[Presentation] 成人肝移植患者におけるエベロリムスの母集団薬物動態解析と小児肝移植患者への外挿2022
- Author(s)
  糸原光太郎、矢野育子、中川俊作、杉本充弘、平井真智子、米澤淳、平大樹、伊藤孝司、秦浩一郎、波多野悦朗、寺田智祐、松原和夫
- Organizer
  第43回日本臨床薬理学会学術総会
- Data Source
  KAKENHI-PROJECT-21K06711
[Presentation] 生理学的薬物速度論モデルを用いたタクロリムスとエベロリムスの体内動態変動因子に関する検討2021
- Author(s)
  山口紗緒里, 中川俊作, 糸原光太郎, 杉本充弘, 梶原望渡, 田上裕美, 米澤　淳, 今井哲司, 中川貴之, 松原和夫, 穴澤貴行, 秦　浩一郎, 田浦康二朗, 寺田智祐
- Organizer
  医療薬学フォーラム2021／第29回クリニカルファーマシーシンポジウム
- Data Source
  KAKENHI-PROJECT-21K06711

Itohara Kotaro 糸原 光太郎

Research Projects

Research Products

The construction of design for personalized dosing for immunosuppressants using pharmacometricsPrincipal Investigator

Principal Investigator

Project Period (FY)

Research Category

Review Section

Research Institution

[Journal Article] Population pharmacokinetics of everolimus in renal transplant recipients receiving long-term multiple immunosuppressive therapy2024

Author(s)

Journal Title

DOI

Data Source

[Journal Article] A model-based pharmacokinetic assessment of drug-drug interaction between tacrolimus and nirmatrelvir/ritonavir in a kidney transplant patient with COVID-192023

Author(s)

Journal Title

DOI

Data Source

[Journal Article] Association between time in therapeutic range of tacrolimus blood concentration and acute rejection within the first three months after lung transplantation2022

Author(s)

Journal Title

DOI

Data Source

[Journal Article] Population pharmacokinetics of everolimus in adult liver transplant patients: Comparison to tacrolimus disposition and extrapolation to pediatrics2022

Author(s)

Journal Title

DOI

Data Source

[Presentation] A model-based pharmacokinetic analysis of drug-drug interaction between nirmatrelvir/ritonavir and tacrolimus2023

Author(s)

Organizer

Data Source

[Presentation] 生理学的薬物動態モデルを活用したタクロリムスの薬物動態予測2023

Author(s)

Organizer

Data Source

[Presentation] 肺移植患者におけるイトラコナゾール併用に着目したタクロリムスの母集団薬物動態解析2023

Author(s)

Organizer

Data Source

[Presentation] ニルマトレルビル/リトナビル併用時にタクロリムス濃度の異常高値を認めた腎移植症例2023

Author(s)

Organizer

Data Source

[Presentation] Population pharmacokinetic analysis and dosing optimization of tacrolimus in lung transplant recipients with itraconazole2023

Author(s)

Organizer

Data Source

[Presentation] 成人肝移植患者におけるエベロリムスの母集団薬物動態解析と小児肝移植患者への外挿2022

Author(s)

Organizer

Data Source

[Presentation] 生理学的薬物速度論モデルを用いたタクロリムスとエベロリムスの体内動態変動因子に関する検討2021

Author(s)

Organizer

Data Source

Itohara Kotaro 糸原光太郎