Nakamae Kazuki 中前和恭

Researcher Number	00882995
Other IDs
Affiliation (Current)	2026: 広島大学, ゲノム編集イノベーションセンター, 共同研究講座助教
Affiliation (based on the past Project Information) *help	2026: 広島大学, ゲノム編集イノベーションセンター, 共同研究講座助教 2022 – 2024: 広島大学, ゲノム編集イノベーションセンター, 共同研究講座助教 2021: 広島大学, ゲノム編集イノベーションセンター, 研究員
Review Section/Research Field	Principal Investigator Basic Section 62010:Life, health and medical informatics-related
Keywords	Principal Investigator パーソナルゲノム / オフターゲット / ゲノム編集 / 表現型 / フェノタイプ・リスク / de novoトランスクリプトーム / RNA-seq / GUIDE-seq / ナノポア / Personalized medicine … More / Prime editing / 遺伝子治療 / ナノポアシーケンス / ナノポアシーケシング / ナノポアシーケンシング / RNAシーケンシング / Prime Editing Less

Research Projects
(3 results)
Research Products
(11 results)

パーソナルゲノム編集のためのフェノタイプ別ノックアウト標的データベースの構築Principal Investigator
- Principal Investigator
  
  中前和恭
- Project Period (FY)
  2026 – 2028
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Review Section
  
  Basic Section 62010:Life, health and medical informatics-related
- Research Institution
  Hiroshima University
Establishment and verification of phenotype risk assessment software for personal genome editingPrincipal Investigator
- Principal Investigator
  
  中前和恭
- Project Period (FY)
  2024 – 2025
- Research Category
  
  Grant-in-Aid for Early-Career Scientists
- Review Section
  
  Basic Section 62010:Life, health and medical informatics-related
- Research Institution
  Hiroshima University
The establishment of the Prime Editing database for personalized genetic medicinePrincipal Investigator
- Principal Investigator
  
  Nakamae Kazuki
- Project Period (FY)
  2021 – 2023
- Research Category
  
  Grant-in-Aid for Early-Career Scientists
- Review Section
  
  Basic Section 62010:Life, health and medical informatics-related
- Research Institution
  Hiroshima University

All 2025 2024 2023 2022 2021

All Journal Article Presentation

[Journal Article] Risk Prediction of RNA Off-Targets of CRISPR Base Editors in Tissue-Specific Transcriptomes Using Language Models2025
- Author(s)
  Nakamae Kazuki、Suzuki Takayuki、Yonezawa Sora、Yamamoto Kentaro、Kakuzaki Taro、Ono Hiromasa、Naito Yuki、Bono Hidemasa
- Journal Title
  
  International Journal of Molecular Sciences
  
  Volume: 26 Issue: 4 Pages: 1723-1723
- DOI
  10.3390/ijms26041723
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-24K20892
[Journal Article] DANGER analysis: risk-averse on/off-target assessment for CRISPR editing without a reference genome2023
- Author(s)
  Nakamae Kazuki、Bono Hidemasa
- Journal Title
  
  Bioinformatics Advances
  
  Volume: 3 Issue: 1
- DOI
  10.1093/bioadv/vbad114
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-21K17855
[Journal Article] Detailed profiling with MaChIAto reveals various genomic and epigenomic features affecting the efficacy of knock-out, short homology-based knock-in and Prime Editing2022
- Author(s)
  Kazuki Nakamae, Mitsumasa Takenaga, Shota Nakade, Akinori Awazu, Naoaki Sakamoto, Takashi Yamamoto, Tetsushi Sakuma
- Journal Title
  
  bioRxiv
  
  Volume: NA
- DOI
  10.1101/2022.06.27.496697
- Open Access
- Data Source
  KAKENHI-PROJECT-21K17855
[Presentation] Novel bioinformatics tools for enhanced safety and activity estimation of genome editing in plant science2024
- Author(s)
  Kazuki Nakamae
- Organizer
  IPSR International Forum on Plant Stress Sciences by/for Junior Researchers 2024
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-24K20892
[Presentation] DANGER Analysis：表現型への影響を評価する新規オフターゲット解析ツール2023
- Author(s)
  中前和恭
- Organizer
  日本ゲノム編集学会第8回大会
- Data Source
  KAKENHI-PROJECT-21K17855
[Presentation] ゲノム編集の安全性評価ソフトウェアの開発安心してゲノム育種に取り組める社会を目指して2023
- Author(s)
  中前和恭
- Organizer
  第46回日本分子生物学会年会
- Data Source
  KAKENHI-PROJECT-21K17855
[Presentation] Computational Resources for Industrial Application of Genome Editing2023
- Author(s)
  Kazuki Nakamae
- Organizer
  JAACT2023
- Invited / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-21K17855
[Presentation] Sequence-based parameters contributing to the efficiency and accuracy of MMEJ-assisted knock-in and Prime Editing2022
- Author(s)
  Kazuki Nakamae
- Organizer
  FASEB: The Genome Engineering Conference: Cutting-edge Research and Applications
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-21K17855
[Presentation] Sequence-based parameters contributing to the efficiency and accuracy of MMEJ-assisted knock-in and Prime Editing2022
- Author(s)
  Kazuki Nakamae
- Organizer
  第45回日本分子生物学会年会
- Data Source
  KAKENHI-PROJECT-21K17855
[Presentation] Sequence-based parameters contributing to the efficiency of MMEJ-assisted knock-in and Prime Editing2021
- Author(s)
  中前和恭
- Organizer
  日本ゲノム編集学会第6回大会
- Data Source
  KAKENHI-PROJECT-21K17855
[Presentation] Sequence-based parameters contributing to the efficiency of MMEJ-assisted knock-in and Prime Editing2021
- Author(s)
  Kazuki Nakamae
- Organizer
  CSHL meeting: GENOME ENGINEERING: CRISPR FRONTIERS
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-21K17855

Nakamae Kazuki 中前 和恭

Research Projects

Research Products

パーソナルゲノム編集のためのフェノタイプ別ノックアウト標的データベースの構築Principal Investigator

Principal Investigator

Project Period (FY)

Research Category

Review Section

Research Institution

Establishment and verification of phenotype risk assessment software for personal genome editingPrincipal Investigator

Principal Investigator

Project Period (FY)

Research Category

Review Section

Research Institution

The establishment of the Prime Editing database for personalized genetic medicinePrincipal Investigator

Principal Investigator

Project Period (FY)

Research Category

Review Section

Research Institution

[Journal Article] Risk Prediction of RNA Off-Targets of CRISPR Base Editors in Tissue-Specific Transcriptomes Using Language Models2025

Author(s)

Journal Title

DOI

Data Source

[Journal Article] DANGER analysis: risk-averse on/off-target assessment for CRISPR editing without a reference genome2023

Author(s)

Journal Title

DOI

Data Source

[Journal Article] Detailed profiling with MaChIAto reveals various genomic and epigenomic features affecting the efficacy of knock-out, short homology-based knock-in and Prime Editing2022

Author(s)

Journal Title

DOI

Data Source

[Presentation] Novel bioinformatics tools for enhanced safety and activity estimation of genome editing in plant science2024

Author(s)

Organizer

Data Source

[Presentation] DANGER Analysis：表現型への影響を評価する新規オフターゲット解析ツール2023

Author(s)

Organizer

Data Source

[Presentation] ゲノム編集の安全性評価ソフトウェアの開発 安心してゲノム育種に取り組める社会を目指して2023

Author(s)

Organizer

Data Source

[Presentation] Computational Resources for Industrial Application of Genome Editing2023

Author(s)

Organizer

Data Source

[Presentation] Sequence-based parameters contributing to the efficiency and accuracy of MMEJ-assisted knock-in and Prime Editing2022

Author(s)

Organizer

Data Source

[Presentation] Sequence-based parameters contributing to the efficiency and accuracy of MMEJ-assisted knock-in and Prime Editing2022

Author(s)

Organizer

Data Source

[Presentation] Sequence-based parameters contributing to the efficiency of MMEJ-assisted knock-in and Prime Editing2021

Author(s)

Organizer

Data Source

[Presentation] Sequence-based parameters contributing to the efficiency of MMEJ-assisted knock-in and Prime Editing2021

Author(s)

Organizer

Data Source

Nakamae Kazuki 中前和恭

[Presentation] ゲノム編集の安全性評価ソフトウェアの開発安心してゲノム育種に取り組める社会を目指して2023