Ogawa Koki 小川昂輝

Researcher Number	00911132
Other IDs
Affiliation (Current)	2025: 名古屋市立大学, 医薬学総合研究院(薬学), 講師
Affiliation (based on the past Project Information) *help	2024 – 2025: 名古屋市立大学, 医薬学総合研究院(薬学), 講師 2022 – 2023: 名古屋市立大学, 医薬学総合研究院(薬学), 助教
Review Section/Research Field	Principal Investigator Basic Section 47060:Clinical pharmacy-related Except Principal Investigator Basic Section 47060:Clinical pharmacy-related / Basic Section 57060:Surgical dentistry-related
Keywords	Principal Investigator 脂質ナノ粒子 / mRNA / 構造 / ポリ乳酸・グリコール酸共重合体（PLGA） / PLGA / 徐放 Except Principal Investigator 3Dプリンター医薬品 / ナノ粒子 / 歯周病 / 口腔白板症 … More / ドラッグデリバリ― / フラボノイド / ワクチン / 粉末吸入剤 / 脂質ナノ粒子 / mRNA Less

Resolving the triangular relationship between periodontal disease, oral cancer, and flavonoids - toward the development of DDS using nanoparticles -
- Principal Investigator
  
  渋谷恭之
- Project Period (FY)
  2025 – 2029
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Review Section
  
  Basic Section 57060:Surgical dentistry-related
- Research Institution
  Nagoya City University
製造段階の有機溶媒組成がmRNA-LNPの構造・機能に与える影響の解明Principal Investigator
- Principal Investigator
  
  小川昂輝
- Project Period (FY)
  2025 – 2027
- Research Category
  
  Grant-in-Aid for Early-Career Scientists
- Review Section
  
  Basic Section 47060:Clinical pharmacy-related
- Research Institution
  Nagoya City University
粘膜ワクチン応用に向けた粉末製剤化mRNA封入脂質ナノ粒子の開発
- Principal Investigator
  
  尾関哲也
- Project Period (FY)
  2023 – 2025
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Review Section
  
  Basic Section 47060:Clinical pharmacy-related
- Research Institution
  Nagoya City University
Pharmaceutical research using 3D printing technology to support the manufacture of medicine
- Principal Investigator
  
  田上辰秋
- Project Period (FY)
  2023
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Review Section
  
  Basic Section 47060:Clinical pharmacy-related
- Research Institution
  Nagoya City University
Development of Sustained-Release mRNA Therapeutics Using Controlled-Release DDS and Its Application to Central Nervous System DisordersPrincipal Investigator
- Principal Investigator
  
  Ogawa Koki
- Project Period (FY)
  2022 – 2024
- Research Category
  
  Grant-in-Aid for Early-Career Scientists
- Review Section
  
  Basic Section 47060:Clinical pharmacy-related
- Research Institution
  Nagoya City University

All 2025 2024 2023

All Journal Article Presentation Patent

[Journal Article] Choice of organic solvent affects function of mRNA-LNP; pyridine produces highly functional mRNA-LNP2025
- Author(s)
  Ogawa Koki、Tagami Tatsuaki、Miyake Satoru、Ozeki Tetsuya
- Journal Title
  
  International Journal of Pharmaceutics
  
  Volume: 673 Pages: 125367-125367
- DOI
  10.1016/j.ijpharm.2025.125367
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-22K15322
[Journal Article] Stable and inhalable powder formulation of mRNA-LNPs using pH-modified spray-freeze drying2024
- Author(s)
  Ogawa Koki、Aikawa Otowa、Tagami Tatsuaki、Ito Takaaki、Tahara Kohei、Kawakami Shigeru、Ozeki Tetsuya
- Journal Title
  
  International Journal of Pharmaceutics
  
  Volume: 665 Pages: 124632-124632
- DOI
  10.1016/j.ijpharm.2024.124632
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-23K06239
[Journal Article] Cholic acid-mediated targeting of mRNA-LNPs improve the mRNA delivery to Caco-2 cells2024
- Author(s)
  Shinkai Toma、Ogawa Koki、Tagami Tatsuaki、Ozeki Tetsuya
- Journal Title
  
  Journal of Nanoparticle Research
  
  Volume: 26 Issue: 11 Pages: 265-265
- DOI
  10.1007/s11051-024-06161-6
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-22K15322
[Journal Article] Fabrication of 3D-Printed Contact Lens Composed of Polyethylene Glycol Diacrylate for Controlled Release of Azithromycin2023
- Author(s)
  Goto Eiichi、Tagami Tatsuaki、Ogawa Koki、Ozeki Tetsuya
- Journal Title
  
  Biological and Pharmaceutical Bulletin
  
  Volume: 46 Issue: 10 Pages: 1461-1467
- DOI
  10.1248/bpb.b23-00443
- ISSN
  0918-6158, 1347-5215
- Year and Date
  2023-10-01
- Language
  English
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-23K06213
[Patent] 核酸封入脂質ナノ粒子の製造方法2024
- Inventor(s)
  小川昂輝、田上先生、尾関哲也、三宅慧
- Industrial Property Rights Holder
  小川昂輝、田上先生、尾関哲也、三宅慧
- Industrial Property Rights Type
  特許
- Industrial Property Number
  2024-012999
- Filing Date
  2024
- Data Source
  KAKENHI-PROJECT-22K15322
[Presentation] 也吸入粉末製剤を目指した粉末化mRNA封入細胞外小胞（mRNA-EVs）の調製2025
- Author(s)
  佐藤一輝、小川昂輝、尾関哲
- Organizer
  日本薬学会第145年会
- Data Source
  KAKENHI-PROJECT-23K06239
[Presentation] mRNA 医薬品の吸入粉末剤に向けた製剤設計2025
- Author(s)
  小川昂輝、佐藤一輝、相川音和、尾関哲也
- Organizer
  日本薬学会第145年会
- Invited
- Data Source
  KAKENHI-PROJECT-23K06239
[Presentation] Selection of organic solvent impacts the function of mRNA-LNP prepared by the solvent dilution method; pyridine produces highly functional mRNA-LNPs2024
- Author(s)
  Koki Ogawa, Satoshi Miyake, Tatsuaki Tagami, Tetsuya Ozeki
- Organizer
  The 40th Annual Meeting of the Japan Society of Drug Delivery System
- Data Source
  KAKENHI-PROJECT-22K15322
[Presentation] 凍結保護剤を用いないmRNA-LNP吸入粉末製剤化法の開発2024
- Author(s)
  小川昂輝、相川音和、田上辰秋、尾関哲也
- Organizer
  日本薬剤学会第39年会
- Data Source
  KAKENHI-PROJECT-23K06239
[Presentation] 改良型溶媒希釈法による葉酸修飾mRNA-LNPの調製2024
- Author(s)
  小川昂輝, 新海斗馬, 三宅慧, 尾関哲也
- Organizer
  第45回生体膜と薬物の相互作用シンポジウム
- Data Source
  KAKENHI-PROJECT-22K15322
[Presentation] ビトロネクチン(Vtn)複合型mRNA-LNP粉末製剤の開発2024
- Author(s)
  相川音和、小川昂輝、尾関哲也
- Organizer
  日本病院薬剤師会東海ブロック・日本薬学会東海支部合同学術大会2024
- Data Source
  KAKENHI-PROJECT-23K06239
[Presentation] 噴霧急速凍結乾燥法を用いた、吸入粉末剤化を目指した mRNA 封入脂質ナノ粒子の開発2023
- Author(s)
  佐藤一輝、ぺ・ヒジュ、新海斗馬、小川昂輝、田上辰秋、尾関哲也
- Organizer
  第40回製剤と粒子設計シンポジウム
- Data Source
  KAKENHI-PROJECT-23K06239
[Presentation] 脂質を溶解する有機溶媒組成に着目したアクティブターゲティング型mRNA封入脂質ナノ粒子のワンステップ調製2023
- Author(s)
  小川昂輝、田上辰秋、尾関哲也
- Organizer
  遺伝子・デリバリー研究会第21回夏季セミナー
- Data Source
  KAKENHI-PROJECT-22K15322

1. 尾関哲也 (60277259)

# of Collaborated Projects: 3 results

# of Collaborated Products: 6 results
2. 田上辰秋 (10609887)

# of Collaborated Projects: 2 results

# of Collaborated Products: 3 results
3. 渋谷恭之 (90335430)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
4. 宮本大模 (10571680)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
5. 土屋周平 (20569785)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
6. 長谷川義明 (70460524)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
7. 梅村直己 (80609107)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
8. 石橋謙一郎 (80714609)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results

Ogawa Koki 小川 昂輝

Research Projects

Research Products

Co-Researchers

Resolving the triangular relationship between periodontal disease, oral cancer, and flavonoids - toward the development of DDS using nanoparticles -

Principal Investigator

Project Period (FY)

Research Category

Review Section

Research Institution

製造段階の有機溶媒組成がmRNA-LNPの構造・機能に与える影響の解明Principal Investigator

Principal Investigator

Project Period (FY)

Research Category

Review Section

Research Institution

粘膜ワクチン応用に向けた粉末製剤化mRNA封入脂質ナノ粒子の開発

Principal Investigator

Project Period (FY)

Research Category

Review Section

Research Institution

Pharmaceutical research using 3D printing technology to support the manufacture of medicine

Principal Investigator

Project Period (FY)

Research Category

Review Section

Research Institution

Development of Sustained-Release mRNA Therapeutics Using Controlled-Release DDS and Its Application to Central Nervous System DisordersPrincipal Investigator

Principal Investigator

Project Period (FY)

Research Category

Review Section

Research Institution

[Journal Article] Choice of organic solvent affects function of mRNA-LNP; pyridine produces highly functional mRNA-LNP2025

Author(s)

Journal Title

DOI

Data Source

[Journal Article] Stable and inhalable powder formulation of mRNA-LNPs using pH-modified spray-freeze drying2024

Author(s)

Journal Title

DOI

Data Source

[Journal Article] Cholic acid-mediated targeting of mRNA-LNPs improve the mRNA delivery to Caco-2 cells2024

Author(s)

Journal Title

DOI

Data Source

[Journal Article] Fabrication of 3D-Printed Contact Lens Composed of Polyethylene Glycol Diacrylate for Controlled Release of Azithromycin2023

Author(s)

Journal Title

DOI

ISSN

Year and Date

Language

Data Source

[Patent] 核酸封入脂質ナノ粒子の製造方法2024

Inventor(s)

Industrial Property Rights Holder

Industrial Property Rights Type

Industrial Property Number

Filing Date

Data Source

[Presentation] 也吸入粉末製剤を目指した粉末化mRNA封入細胞外小胞（mRNA-EVs）の調製2025

Author(s)

Organizer

Data Source

[Presentation] mRNA 医薬品の吸入粉末剤に向けた製剤設計2025

Author(s)

Organizer

Data Source

[Presentation] Selection of organic solvent impacts the function of mRNA-LNP prepared by the solvent dilution method; pyridine produces highly functional mRNA-LNPs2024

Author(s)

Organizer

Data Source

[Presentation] 凍結保護剤を用いないmRNA-LNP吸入粉末製剤化法の開発2024

Author(s)

Organizer

Data Source

Ogawa Koki 小川昂輝