Chihara Kotaro 千原康太郎

Researcher Number	00976946
Other IDs
Affiliation (Current)	2026: 国立健康危機管理研究機構, 国立感染症研究所治療薬開発研究部, 研究員
Affiliation (based on the past Project Information) *help	2025: 国立健康危機管理研究機構, 治療薬・ワクチン開発研究センター, 研究員 2024: 国立感染症研究所, 治療薬開発研究部, 研究員 2023 – 2024: 国立感染症研究所, 治療薬・ワクチン開発研究センター, 研究員
Review Section/Research Field	Principal Investigator Basic Section 49050:Bacteriology-related / 0803:Pathology, infection/immunology, and related fields
Keywords	Principal Investigator 薬剤耐性菌 / 核酸検出 / 阻害因子 / 細胞内複合体解析 / ファージ療法 / RNA-seq / ファージ防御システム / 可動遺伝因子 / tRNA / 抗ファージ防御システム / バクテリオファージ

薬剤耐性菌を狙い撃つ遺伝子標的型抗菌療法の開発Principal Investigator
- Principal Investigator
  
  千原康太郎
- Project Period (FY)
  2025 – 2027
- Research Category
  
  Grant-in-Aid for Early-Career Scientists
- Review Section
  
  Basic Section 49050:Bacteriology-related
- Research Institution
  Japan Institute for Health Security
Functional Characterization of the New Phage Defense System and Exploration of the Inhibitory FactorsPrincipal Investigator
- Principal Investigator
  
  Chihara Kotaro
- Project Period (FY)
  2023 – 2024
- Research Category
  
  Grant-in-Aid for Research Activity Start-up
- Review Section
  
  0803:Pathology, infection/immunology, and related fields
- Research Institution
  National Institute of Infectious Diseases

All 2025 2024 2023

All Journal Article Presentation

[Journal Article] Phage engineering to overcome bacterial Tmn immunity in Dhillonvirus2025
- Author(s)
  Yamashita Wakana、Chihara Kotaro、Azam Aa Haeruman、Kondo Kohei、Ojima Shinjiro、Tamura Azumi、Imanaka Matthew、Nobrega Franklin L.、Takahashi Yoshimasa、Watashi Koichi、Tsuneda Satoshi、Kiga Kotaro
- Journal Title
  
  Communications Biology
  
  Volume: 8 Issue: 1 Pages: 1-9
- DOI
  10.1038/s42003-025-07730-8
- Peer Reviewed / Open Access / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-23K13876, KAKENHI-PROJECT-23K19475, KAKENHI-PROJECT-22KJ1099, KAKENHI-PROJECT-23K21171
[Journal Article] Evasion of antiviral bacterial immunity by phage tRNAs2024
- Author(s)
  Azam Aa Haeruman、Kondo Kohei、Chihara Kotaro、Nakamura Tomohiro、Ojima Shinjiro、Nie Wenhan、Tamura Azumi、Yamashita Wakana、Sugawara Yo、Sugai Motoyuki、Cui Longzhu、Takahashi Yoshimasa、Watashi Koichi、Kiga Kotaro
- Journal Title
  
  Nature Communications
  
  Volume: 15 Issue: 1 Pages: 1-10
- DOI
  10.1038/s41467-024-53789-y
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-23K13876, KAKENHI-PROJECT-23K19475, KAKENHI-PROJECT-22KJ1099, KAKENHI-PROJECT-23K21171, KAKENHI-PROJECT-23KJ2059
[Journal Article] Synthetic phage-based approach for sensitive and specific detection of Escherichia coli O1572024
- Author(s)
  Tamura Azumi、Azam Aa Haeruman、Nakamura Tomohiro、Lee Kenichi、Iyoda Sunao、Kondo Kohei、Ojima Shinjiro、Chihara Kotaro、Yamashita Wakana、Cui Longzhu、Akeda Yukihiro、Watashi Koichi、Takahashi Yoshimasa、Yotsuyanagi Hiroshi、Kiga Kotaro
- Journal Title
  
  Communications Biology
  
  Volume: 7 Issue: 1 Pages: 535-535
- DOI
  10.1038/s42003-024-06247-w
- Peer Reviewed / Open Access / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-23K19475, KAKENHI-PROJECT-22K20575, KAKENHI-PROJECT-24H00662, KAKENHI-PROJECT-21K07017, KAKENHI-PROJECT-23K13876, KAKENHI-PROJECT-22KJ1099, KAKENHI-PROJECT-23K21171, KAKENHI-PROJECT-24K02282, KAKENHI-PROJECT-23KJ2059
[Presentation] 利己的な可動遺伝因子によるファージ防御システム回避機構2025
- Author(s)
  千原康太郎、アアハエルマンアザム、氣駕恒太朗
- Organizer
  第98回日本細菌学会総会
- Data Source
  KAKENHI-PROJECT-23K19475
[Presentation] Evasion of phage defense system facilitated by mobile genetic element2025
- Author(s)
  Kotaro Chihara, Aa Haeruman Azam, Kotaro Kiga
- Organizer
  Danish Viruses of Microbes Network
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-23K19475
[Presentation] 様々なファージ因子を認識して活性化する抗ファージ防御システムSeptuの多様性2024
- Author(s)
  千原康太郎、近藤恒平、アアハエルマンアザム、小島新二郎、菅原庸、菅井基行、高橋宜聖、渡士幸一、氣駕恒太朗
- Organizer
  第97回日本細菌学会総会
- Data Source
  KAKENHI-PROJECT-23K19475
[Presentation] ファージ防御システム Septu は多様なファージ由来因子を認識して活性化する2024
- Author(s)
  千原康太郎、近藤恒平、アアハエルマンアザム、小島新二郎、菅原庸、菅井基行、渡士幸一、高橋宜聖、氣駕恒太朗
- Organizer
  第20回大腸菌研究会
- Data Source
  KAKENHI-PROJECT-23K19475
[Presentation] DIVERSITY OF SEPTU ANTI-PHAGE SYSTEM TRIGGERED BY DISTINCT PHAGE COMPONENTS2024
- Author(s)
  Kotaro Chihara, Kohei Kondo, Aa Haeruman Azam, Shinjiro Ojima, Yo Sugawara, Motoyuki Sugai, Yoshimasa Takahashi, Koichi Watashi, Kotaro Kiga
- Organizer
  Viruses of Microbes 2024
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-23K19475
[Presentation] ファージ防御システムがファージ感染を検知する機能的多様性2024
- Author(s)
  千原康太郎、近藤恒平、アアハエルマンアザム、小島新二郎、菅原庸、菅井基行、氣駕恒太朗
- Organizer
  第4回ファージセラピー研究会
- Data Source
  KAKENHI-PROJECT-23K19475
[Presentation] 大腸菌臨床株に保存された新規ファージ防御システムの多様性とファージ防御能の評価2023
- Author(s)
  千原康太郎、近藤恒平、アザムアアハエルマン、小島新二郎、菅原庸、氣駕恒太朗
- Organizer
  第19回21世紀大腸菌研究会
- Data Source
  KAKENHI-PROJECT-23K19475

1. アザムアア

# of Collaborated Projects: 0 results

# of Collaborated Products: 2 results

Chihara Kotaro 千原 康太郎

Research Projects

Research Products

Co-Researchers

薬剤耐性菌を狙い撃つ遺伝子標的型抗菌療法の開発Principal Investigator

Principal Investigator

Project Period (FY)

Research Category

Review Section

Research Institution

Functional Characterization of the New Phage Defense System and Exploration of the Inhibitory FactorsPrincipal Investigator

Principal Investigator

Project Period (FY)

Research Category

Review Section

Research Institution

[Journal Article] Phage engineering to overcome bacterial Tmn immunity in Dhillonvirus2025

Author(s)

Journal Title

DOI

Data Source

[Journal Article] Evasion of antiviral bacterial immunity by phage tRNAs2024

Author(s)

Journal Title

DOI

Data Source

[Journal Article] Synthetic phage-based approach for sensitive and specific detection of Escherichia coli O1572024

Author(s)

Journal Title

DOI

Data Source

[Presentation] 利己的な可動遺伝因子によるファージ防御システム回避機構2025

Author(s)

Organizer

Data Source

[Presentation] Evasion of phage defense system facilitated by mobile genetic element2025

Author(s)

Organizer

Data Source

[Presentation] 様々なファージ因子を認識して活性化する抗ファージ防御システムSeptuの多様性2024

Author(s)

Organizer

Data Source

[Presentation] ファージ防御システム Septu は多様な ファージ由来因子を認識して活性化する2024

Author(s)

Organizer

Data Source

[Presentation] DIVERSITY OF SEPTU ANTI-PHAGE SYSTEM TRIGGERED BY DISTINCT PHAGE COMPONENTS2024

Author(s)

Organizer

Data Source

[Presentation] ファージ防御システムがファージ感染を検知する機能的多様性2024

Author(s)

Organizer

Data Source

[Presentation] 大腸菌臨床株に保存された新規ファージ防御システムの多様性とファージ防御能の評価2023

Author(s)

Organizer

Data Source

Chihara Kotaro 千原康太郎

[Presentation] ファージ防御システム Septu は多様なファージ由来因子を認識して活性化する2024