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Chiba Shiho  千葉 志穂

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千葉 志穂  チバ シホ

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Researcher Number 00987802
Other IDs
Affiliation (Current) 2026: 国立健康危機管理研究機構, 国立国際医療研究所, 上級研究員
Affiliation (based on the past Project Information) *help 2024: 東京大学, 新世代感染症センター, 特任助教
Review Section/Research Field
Principal Investigator
Basic Section 49060:Virology-related
Keywords
Principal Investigator
ユニバーサルワクチン / モノクローナル抗体 / ヘマグルチニンタンパク質 / インフルエンザウイルス / 交差結合性抗体
  • Research Projects

    (1 results)
  • Research Products

    (8 results)
  •  インフルエンザウイルスHAに交差結合特異性を示す抗体の防御機序の解析Principal Investigator

    • Principal Investigator
      千葉 志穂
    • Project Period (FY)
      2024 – 2026
    • Research Category
      Grant-in-Aid for Scientific Research (C)
    • Review Section
      Basic Section 49060:Virology-related
    • Research Institution
      The University of Tokyo

All 2024

All Journal Article Presentation

  • [Journal Article] Single immunization with an influenza <scp>hemagglutinin</scp> nanoparticle‐based vaccine elicits durable protective immunity2024

    • Author(s)
      Chiba Shiho、Maemura Tadashi、Loeffler Kathryn、Frey Steven J.、Gu Chunyang、Biswas Asim、Hatta Masato、Kawaoka Yoshihiro、Kane Ravi S.
    • Journal Title

      Bioengineering &amp; Translational Medicine

      Volume: 9 Issue: 5

    • DOI

      10.1002/btm2.10689

    • Peer Reviewed / Int'l Joint Research
    • Data Source
      KAKENHI-PROJECT-24K10243
  • [Journal Article] An mRNA vaccine candidate encoding H5HA clade 2.3.4.4b protects mice from clade 2.3.2.1a virus infection2024

    • Author(s)
      Chiba Shiho、Kiso Maki、Yamada Shinya、Someya Kazuhiko、Onodera Yoshikuni、Yamaguchi Aya、Matsunaga Satoko、Uraki Ryuta、Iwatsuki-Horimoto Kiyoko、Yamayoshi Seiya、Takeshita Fumihiko、Kawaoka Yoshihiro
    • Journal Title

      npj Vaccines

      Volume: 9 Issue: 1

    • DOI

      10.1038/s41541-024-00988-9

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-24K10243
  • [Journal Article] Protective effects of an mRNA vaccine candidate encoding H5HA clade 2.3.4.4b against the newly emerged dairy cattle H5N1 virus2024

    • Author(s)
      Chiba Shiho、Kiso Maki、Yamada Shinya、Someya Kazuhiko、Onodera Yoshikuni、Yamaguchi Aya、Matsunaga Satoko、Jounai Nao、Yamayoshi Seiya、Takeshita Fumihiko、Kawaoka Yoshihiro
    • Journal Title

      eBioMedicine

      Volume: 109 Pages: 105408-105408

    • DOI

      10.1016/j.ebiom.2024.105408

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-24K10243
  • [Presentation] Protective mechanisms of human monoclonal antibodies cross-reactive against antigenically divergent influenza H3HA2024

    • Author(s)
      Shiho Chiba Yoshihiro Kawaoka
    • Organizer
      World Flu Day 2024 Symposium
    • Int'l Joint Research
    • Data Source
      KAKENHI-PROJECT-24K10243
  • [Presentation] 抗原性の異なるインフルエンザH3HAに交差防御能をもつヒト抗体の作用機序の解析2024

    • Author(s)
      千葉志穂, Gabriele Neumann, 河岡義裕
    • Organizer
      第71回日本ウイルス学会学術集会
    • Data Source
      KAKENHI-PROJECT-24K10243
  • [Presentation] 抗原性の異なるインフルエンザH3HAに交差防御能をもつヒト抗体の作用機序の解析2024

    • Author(s)
      千葉志穂, Gabriele Neumann, 河岡義裕
    • Organizer
      第47回日本分子生物学会年会
    • Data Source
      KAKENHI-PROJECT-24K10243
  • [Presentation] Influenza H3 hemagglutinin vaccine with scrambled immuno-dominant epitopes elicits antibodies directed toward immuno-subdominant head epitopes2024

    • Author(s)
      Shiho Chiba, Huihui Kong, Gabriele Neumann, and Yoshihiro Kawaoka
    • Organizer
      OPTIONS XII 2024 Congress
    • Int'l Joint Research
    • Data Source
      KAKENHI-PROJECT-24K10243
  • [Presentation] 主要抗原決定基を多様化させたインフルエンザHAワクチンは非主要抗原決定基を標的とする抗体を誘導し, 感染防御に寄与する2024

    • Author(s)
      千葉志穂, Huihui Kong, Gabriele Neumann, 河岡義裕
    • Organizer
      第37回インフルエンザ研究者交流の会
    • Data Source
      KAKENHI-PROJECT-24K10243

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