HIGUCHI Yoshihiro 樋口善博

Researcher Number	10019630
Other IDs
External Links
Affiliation (based on the past Project Information) *help	2015: 鈴鹿医療科学大学, 薬学部, 教授 2010 – 2012: 鈴鹿医療科学大学, 薬学部, 教授 2003 – 2005: 金沢大学, 医学系研究科, 助手 2001 – 2002: 金沢大学, 大学院・医学系研究科, 助手 2001: Kanazawa University Graduate School of Medical Science, 大学院・医学研究科, 助手 1998 – 2000: 金沢大学, 医学部, 助手
Review Section/Research Field	Principal Investigator Biological pharmacy / Structural biochemistry / Pathological medical chemistry Except Principal Investigator General physiology / General medical chemistry / Pediatrics
Keywords	Principal Investigator グルタミン酸 / アポトーシス / グルタチオン / アラキドン酸 / ネクローシス / 脂質過酸化 / 巨大DNA断片化 / 紫外線 / 細胞死 / プロテオミクス … More / シグナル伝達 / ストレス / タンパク質 / 脳神経疾患 / GRP-78 / Galectin-1 / プロテオミクス解析 / 老化 / プロテインキナーゼC / シグナル伝津 / グリア細胞 / カスパーゼ-3 / リポオキシゲナーゼ / DNA断片化 / ポリADPリボースポリメラーゼ / 活性酸素 / glutathion / glutamate / arachidonic acid / apoptosis / necrosis / glioma cells / lipid peroxidation / giant DNA fragmentation / グリア細胞腫 / グルタチオン枯渇 / 紫外線照射 / DNA損傷 / 8-ヒドロキシグアノシン / スパーゼ / 酸素フリーラジカル / ポリ(ADP-リボース)ポリメラーゼ / ATP / 12-リポオキシゲナーゼ / 不飽和脂肪酸 / Glutamate / Glia / Apoptosis / Necrosis / Glutathione / Ultraviolet / Giant DNA fragmentation / Lipid peroxidation … More Except Principal Investigator プロテオミクス / CD38 / サイクリックADPリボース / カルシウムイオン / 結合蛋白 / cADPリボース / カルシウム / リン酸化 / エピトーグタグ / 免疫沈降 / リポキシゲナーゼ / マクロファージ / 酸化LDL / LDL受容体関連蛋白 / コレステロールエステル / トランスロケーション / 12 / 15-リポキシゲナーゼ / 受容体 / スカベンジャー受容体 / Lipoxygenase / Macrophage / Oxidized LDL / LDL receptor-related protein / Cholesterol ester / Translocation / 酸化ストレス / 興奮毒性 / カルボニル化 / グリア細胞 / 神経細胞死 Less

Proteomic identification of oxidatively damaged proteins in excitotoxin-induced cell death
- Principal Investigator
  
  Furukawa Ayako
- Project Period (FY)
  2013 – 2015
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Research Field
  
  Pediatrics
- Research Institution
  Suzuka University of Medical Science
Study on some proteins controling cell death in oxidative stress-induced neuronal cell death.Principal Investigator
- Principal Investigator
  
  HIGUCHI Yoshihiro
- Project Period (FY)
  2010 – 2012
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Research Field
  
  Biological pharmacy
- Research Institution
  Suzuka University of Medical Science
Activation mechanism of cyclic ADP-ribose-synthesizing enzyme CD38
- Principal Investigator
  
  MINAKO Hashii
- Project Period (FY)
  2010 – 2012
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Research Field
  
  General physiology
- Research Institution
  Kanazawa University
The study on the glutamate-induced glial cell death mechanism for modulation of apoptosis to necrosis by arachidonic acid-mediated lipid peroxidationPrincipal Investigator
- Principal Investigator
  
  HIGUCHI Yoshihiro
- Project Period (FY)
  2003 – 2005
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Research Field
  
  Pathological medical chemistry
- Research Institution
  Kanazawa University Graduate School of Medical Science
Pathophysiological role of lipid molecules produced by 12/l5-lipoxygenase
- Principal Investigator
  
  YOSHIMOTO Tanihiro
- Project Period (FY)
  2000 – 2002
- Research Category
  
  Grant-in-Aid for Scientific Research (B)
- Research Field
  
  General medical chemistry
- Research Institution
  Kanazawa University
Role of arachdonate cascade in apoptosis of neronal cellsPrincipal Investigator
- Principal Investigator
  
  HIGUCHI Yoshihiro
- Project Period (FY)
  1998 – 2000
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Research Field
  
  Structural biochemistry
- Research Institution
  Kanazawa University

All 2016 2015 2014 2012 2011 2010 2006 2005 2004 2003 Other

All Journal Article Presentation

[Journal Article] (Review) The role of endonucleases in chromosomal DNA fragmentation associated with apoptosis and necrosis.2006
- Author(s)
  Higuchi Y.
- Journal Title
  
  Cell Apoptosis Res. (印刷中)
- Description
  「研究成果報告書概要(和文)」より
- Data Source
  KAKENHI-PROJECT-15590268
[Journal Article] (Review) The role of endonucleases in chromosomal DNA fragmentation associated with apoptosis and necrosis.2006
- Author(s)
  Higuchi, Y.
- Journal Title
  
  Cell Apoptosis Res. (印刷中)
- Description
  「研究成果報告書概要(欧文)」より
- Data Source
  KAKENHI-PROJECT-15590268
[Journal Article] The role of lipid peroxidation in chromosomal DNA frag-mentation associated with cell death induced by glutathione depletion.2006
- Author(s)
  Higuchi Y, Tanii H, Mizukami Y, Yoshimoto T
- Journal Title
  
  Molecular Interventions and Protection in Lifestyle Related Diseases
  
  Pages: 287-302
- Data Source
  KAKENHI-PROJECT-15590268
[Journal Article] The role of lipid peroxidation in chromosomal DNA frag-mentation associated with cell death induced by glutathione depletion.2006
- Author(s)
  Higuchi Y., Tanii H., Mizukami Y., Yoshimoto T.
- Journal Title
  
  Molecular Interventions and Protection in Lifestyle Related Diseases ((Taylor & Francis)
  
  Pages: 287-302
- Description
  「研究成果報告書概要(和文)」より
- Data Source
  KAKENHI-PROJECT-15590268
[Journal Article] (Review) Antitumor and biological effects of Streptococcus pyogenes2006
- Author(s)
  Higuchi Y.
- Journal Title
  
  Trends in Cancer Res. (印刷中)
- Description
  「研究成果報告書概要(和文)」より
- Data Source
  KAKENHI-PROJECT-15590268
[Journal Article] (Review) The role of lipid peroxidation in chromosomal DN frag-mentation associated with cell death induced by glutathione depletion.2005
- Author(s)
  Higuchi, Y., Tanii, H., Mizukami, Y., Yoshimoto, T.
- Journal Title
  
  Molecular Interventions and Protection in Lifestyle Related Diseases (Taylor & Francis)
  
  Pages: 287-302
- Description
  「研究成果報告書概要(欧文)」より
- Data Source
  KAKENHI-PROJECT-15590268
[Journal Article] Sulindac activates nuclear translocation of DFF40 and Endonuclease G but not induces oligonucleosomal DNA fragmentation in HT-29 cells.2005
- Author(s)
  Park YC, Jeong JH, Park KJ, Choi HJ, Park YM, Jeong BK, Higuchi Y, Yoo YH
- Journal Title
  
  Life Science 77
  
  Pages: 2059-2070
- Description
  「研究成果報告書概要(和文)」より
- Data Source
  KAKENHI-PROJECT-15590268
[Journal Article] (Review) Pathological changes induced by allylnitrile and crotononitrile: relationship with behavioral abnormalities.2005
- Author(s)
  Tanii H., Higuchi Y., Saijoh K.
- Journal Title
  
  Current Topics in Toxicology 1
  
  Pages: 87-94
- Description
  「研究成果報告書概要(和文)」より
- Data Source
  KAKENHI-PROJECT-15590268
[Journal Article] Pathological changes induced by allylnitrile and crotononitrile : relationship with behavioral abnormalities2005
- Author(s)
  Tanii H, Higuchi Y, Saijoh K
- Journal Title
  
  Current Topics in Toxicology 1
  
  Pages: 87-94
- Data Source
  KAKENHI-PROJECT-15590268
[Journal Article] (Review) Antitumor and biological effects of Streptococcus pyogenes2005
- Author(s)
  Higuchi, Y.
- Journal Title
  
  Trends in Cancer Res. (印刷中)
- Description
  「研究成果報告書概要(欧文)」より
- Data Source
  KAKENHI-PROJECT-15590268
[Journal Article] Induction of detoxication enzymes in mice by naturally occurring allyl nitrile.2005
- Author(s)
  Tanii H., Higashi T., Nishimura F., Higuchi Y, Saijoh K.
- Journal Title
  
  J. Agric. Food Chem. 53
  
  Pages: 8993-8996
- Description
  「研究成果報告書概要(和文)」より
- Data Source
  KAKENHI-PROJECT-15590268
[Journal Article] Induction of detoxication enzymes in mice by naturally occurring allyl nitrile2005
- Author(s)
  Tanii H, Higashi T, Nishimura F, Higuchi Y, Saijoh K
- Journal Title
  
  J.Agric.Food Chem. 53
  
  Pages: 8993-8996
- Data Source
  KAKENHI-PROJECT-15590268
[Journal Article] Induction of detoxication enzymes in mice by naturally occurring allylnitrile.2005
- Author(s)
  Tanii, H., Higashi, T., Nishimura, F., Higuchi, Y., Saijoh, K.
- Journal Title
  
  J.Agric.Food Chem. 53
  
  Pages: 8993-8996
- Description
  「研究成果報告書概要(欧文)」より
- Data Source
  KAKENHI-PROJECT-15590268
[Journal Article] (Review) Glutathione depletion-induced chromosomal DNA fragmentation associated with apoptosis and necrosis.2004
- Author(s)
  Higuchi, Y.
- Journal Title
  
  J.Cell Mol.Med. 8(4)
  
  Pages: 455-464
- Description
  「研究成果報告書概要(欧文)」より
- Data Source
  KAKENHI-PROJECT-15590268
[Journal Article] Promoting effect of polyunsaturated fatty acids on chromosomal giant DNA fragmentation associated with cell death induced by glutathione depletion.2004
- Author(s)
  Higuchi, Y., Yoshimoto, T.
- Journal Title
  
  Free Radical Research 38・6
  
  Pages: 649-658
- Data Source
  KAKENHI-PROJECT-15590268
[Journal Article] Glutathione depletion-induced chromosomal DNA fragmentation associated with apoptosis and necrosis.2004
- Author(s)
  Higuchi, Y.
- Journal Title
  
  J.Cellular Molecular Medicine 8・4
  
  Pages: 455-464
- Data Source
  KAKENHI-PROJECT-15590268
[Journal Article] (Review) Glutathione depletion-induced chromosomal DNA frag-mentation associated with apoptosis and necrosis.2004
- Author(s)
  Higuchi Y.
- Journal Title
  
  J. Cell Mol Med. 8.4
  
  Pages: 455-464
- Description
  「研究成果報告書概要(和文)」より
- Data Source
  KAKENHI-PROJECT-15590268
[Journal Article] Promoting effect of polyunsaturated fatty acids on chromosomal giant DNA fragmentation associated with cell death induced by glitathione depletion.2004
- Author(s)
  Higuchi Y., Yoshimoto T.
- Journal Title
  
  Free Radical Res. 38.6
  
  Pages: 649-658
- Description
  「研究成果報告書概要(和文)」より
- Data Source
  KAKENHI-PROJECT-15590268
[Journal Article] Promoting effect of polyunsaturated fatty acids on chromosomal giant DNA fragmentation associated with cell death induced by glutathione depletion.2004
- Author(s)
  Higuchi, Y., Yoshimoto, T.
- Journal Title
  
  Free Radical Res 38(6)
  
  Pages: 649-658
- Description
  「研究成果報告書概要(欧文)」より
- Data Source
  KAKENHI-PROJECT-15590268
[Journal Article] (Review) Pathological changes induced by allylnitrile and crotononitrile : relationship with behavioral abnormalities.2004
- Author(s)
  Tanii, H., Higuchi, Y., Saijoh, K.
- Journal Title
  
  Current Topics in Toxicology. 1
  
  Pages: 87-94
- Description
  「研究成果報告書概要(欧文)」より
- Data Source
  KAKENHI-PROJECT-15590268
[Journal Article] (Review) Chromosomal DNA fragmentation in apoptosis and necrosis induced by oxidative stress.2003
- Author(s)
  Higuchi, Y.
- Journal Title
  
  Biochem.Pharmacol. 66(8)
  
  Pages: 127-1535
- Description
  「研究成果報告書概要(欧文)」より
- Data Source
  KAKENHI-PROJECT-15590268
[Journal Article] (Review) Chromosomal DNA fragmentation in apoptosis and necrosis induced by oxidative stress.2003
- Author(s)
  Higuchi Y.
- Journal Title
  
  Biochem. Pharmacol. 66.8
  
  Pages: 1527-1535
- Description
  「研究成果報告書概要(和文)」より
- Data Source
  KAKENHI-PROJECT-15590268
[Journal Article] Ultraviolet ray induces chromosomal giant DNA fragmentation followed by internucleosomal DNA fragmentation associated with apoptosis in rat glioma cells2003
- Author(s)
  Higuchi Y, Mizukami Y, Yoshimoto T.
- Journal Title
  
  Ann. NY Acad. Sci. 1010
  
  Pages: 326-330
- Description
  「研究成果報告書概要(和文)」より
- Data Source
  KAKENHI-PROJECT-15590268
[Journal Article] Ultraviolet ray induces chromosomal giant DNA fragmentation followed by inter-nucleosomal DNA fragmentation associated with apoptosis in rat glioma cells.2003
- Author(s)
  Higuchi, Y., Mizukami, Y., Yoshimoto, T.
- Journal Title
  
  Ann.NY Acad.Sci. 1010
  
  Pages: 326-330
- Description
  「研究成果報告書概要(欧文)」より
- Data Source
  KAKENHI-PROJECT-15590268
[Presentation] グルタミン酸によるグリア細胞死誘導において生成する酸化損傷タンパク質の検出2016
- Author(s)
  近藤美帆、古川絢子、樋口善博
- Organizer
  日本酸化ストレス学会東海支部・第４回学術集会
- Place of Presentation
  鈴鹿医療科学大学白子キャンパス
- Year and Date
  2016-02-06
- Data Source
  KAKENHI-PROJECT-25461565
[Presentation] グルタミン酸によるグリア障害におけるタンパク質の発現変動および酸化損傷解析2015
- Author(s)
  古川絢子、樋口善博
- Organizer
  BMB2015　第88回日本生化学会
- Place of Presentation
  神戸国際展示場
- Year and Date
  2015-12-03
- Data Source
  KAKENHI-PROJECT-25461565
[Presentation] グルタミン酸によるグリア細胞死誘導における酸化損傷タンパク質の役割解明2015
- Author(s)
  古川絢子、近藤美帆、梨本明日香、樋口善博
- Organizer
  日本薬学会　第135年会
- Place of Presentation
  神戸
- Year and Date
  2015-03-28
- Data Source
  KAKENHI-PROJECT-25461565
[Presentation] 内側側頭葉てんかん患者の海馬硬化組織特異的な酸化損傷タンパク質の同定2014
- Author(s)
  古川絢子、柿田明美、千葉陽一、樋口善博、高橋均、亀山茂樹、島田厚良
- Organizer
  第55回日本神経病理学会
- Place of Presentation
  東京
- Year and Date
  2014-06-07
- Data Source
  KAKENHI-PROJECT-25461565
[Presentation] Proteomic identification of oxidatively damaged proteins in the sclerotic hippocampus of patients with mesial temporal lobe epilepsy2014
- Author(s)
  Ayako Furukawa, Akiyoshi Kakita, Yoichi Chiba, Yoshihiro Higuchi, Atsuyoshi Shimada
- Organizer
  SFRRI2014
- Place of Presentation
  京都国際会議場
- Data Source
  KAKENHI-PROJECT-25461565
[Presentation] Proteomic analysis of some proteins controlling glutamate-induced cell death associated with apoptosis in rat C6 glioma cells.2014
- Author(s)
  Ayako Furukawa, Ayaka Hoshizaki and Yoshihiro Higuchi
- Organizer
  SFRRI2014
- Place of Presentation
  京都国際会議場
- Data Source
  KAKENHI-PROJECT-25461565
[Presentation] グルタミン酸によるグリア細胞死誘導に関わる細胞内タンパク因子のプロテオミクス解析2014
- Author(s)
  星崎彩加、古川絢子、梨本明日香、近藤美帆、樋口善博
- Organizer
  第６０回　日本薬学会東海支部大会
- Place of Presentation
  三重県
- Year and Date
  2014-07-05
- Data Source
  KAKENHI-PROJECT-25461565
[Presentation] Proteomic identification of oxidatively damaged proteins in excitotoxin-induced hippocampal injury2012
- Author(s)
  Furukawa, A. Shimada, A. and Higuchi
- Organizer
  14th International Congress of Histochemistry and Cytochemistry (ICHC 2012)
- Place of Presentation
  京都
- Year and Date
  2012-08-29
- Data Source
  KAKENHI-PROJECT-22590091
[Presentation] 二酸化チタンナノ粒子による活性酸素非依存的細胞死誘導2012
- Author(s)
  樋口善博、高木圭子、清水宣明, 古川絢子, 橋井美奈子
- Organizer
  第85回日本薬理学会
- Place of Presentation
  京都市
- Year and Date
  2012-03-15
- Data Source
  KAKENHI-PROJECT-22590091
[Presentation] 二酸化チタンナノ粒子による活性酸素非依存的細胞死誘導2012
- Author(s)
  樋口善博、高木圭子、清水宣明,古川絢子,橋井美奈子
- Organizer
  第85回日本薬理学会
- Place of Presentation
  京都
- Year and Date
  2012-03-15
- Data Source
  KAKENHI-PROJECT-22590091
[Presentation] 内側側頭葉てんかん患者の海馬硬化組織における酸化損傷タンパク質の検出と同定2012
- Author(s)
  古川絢子,柿田明美,千葉陽一,武井史郎,石井さなえ,河村則子,細川昌則,樋口善博,高橋均,島田厚良
- Organizer
  日本神経病理学会
- Place of Presentation
  新潟
- Year and Date
  2012-06-24
- Data Source
  KAKENHI-PROJECT-22590091
[Presentation] A. and Shimizu, N., TiO2 particles induces apoptosis associated with chromosomal DNA fragmentation and without ROS production in L1210 leukemia cells.2012
- Author(s)
  Higuchi, Y., Takaki, K, Furukawa
- Organizer
  16th SFRRI BiennialMeeting
- Place of Presentation
  ロンドン
- Year and Date
  2012-09-08
- Data Source
  KAKENHI-PROJECT-22590091
[Presentation] 興奮毒性による海馬神経細胞死に関与する酸化損傷タンパク質の網羅的解析2012
- Author(s)
  古川絢子,樋口善博,島田厚良
- Organizer
  日本薬学会第131回年会
- Place of Presentation
  札幌
- Year and Date
  2012-03-29
- Data Source
  KAKENHI-PROJECT-22590091
[Presentation] 二酸化チタンナノ粒子による活性酸素を介しない細胞死誘導2012
- Author(s)
  樋口善博、古川絢子,高木圭子、清水宣明
- Organizer
  日本社会薬学会第31回年会
- Place of Presentation
  鈴鹿
- Year and Date
  2012-09-16
- Data Source
  KAKENHI-PROJECT-22590091
[Presentation] 紫外線誘導アポトーシスにおける染色体DNA断片化と細胞内関連因子の動態2012
- Author(s)
  樋口善博,古川絢子
- Organizer
  フォーラム2012:衛生薬学・環境トキシコロジー
- Place of Presentation
  名古屋
- Year and Date
  2012-10-25
- Data Source
  KAKENHI-PROJECT-22590091
[Presentation] Effect of zonisamide on apoptosis-related factors formedduring iron-induced epileptogenesis in rat brain.2012
- Author(s)
  Higuchi, Y., Furukawa, A., Oowada, S., Komatsu, M. and Hiramatsu, M.
- Organizer
  14th International Congress of Histochemistry and Cytochemistry (ICHC 2012)
- Place of Presentation
  京都
- Year and Date
  2012-08-27
- Data Source
  KAKENHI-PROJECT-22590091
[Presentation] 食品中に含まれる有効成分の安全性評価その1:カテキン類のDNA損傷性2012
- Author(s)
  古川絢子,樋口善博,村田真理子,及川伸二,川西正祐
- Organizer
  日本社会薬学会第31回年会
- Place of Presentation
  鈴鹿
- Year and Date
  2012-09-16
- Data Source
  KAKENHI-PROJECT-22590091
[Presentation] 紫外線照射誘導アポトーシスにおける活性酸素非依存的染色体巨大DNA断片化2012
- Author(s)
  樋口善博、古川絢子, 橋井美奈子
- Organizer
  日本薬学会第131回年会
- Place of Presentation
  札幌市
- Year and Date
  2012-03-29
- Data Source
  KAKENHI-PROJECT-22590091
[Presentation] 興奮毒性による海馬神経細胞死に関与する酸化損傷タンパク質の網羅的解析2012
- Author(s)
  古川絢子, 樋口善博, 島田厚良
- Organizer
  日本薬学会第131回年会
- Place of Presentation
  札幌市
- Year and Date
  2012-03-29
- Data Source
  KAKENHI-PROJECT-22590091
[Presentation] Reactive-oxygen species-independent chromosomal giant dna fragmentation associated with caspase-mediated apoptosis in ultraviolet-irradiated cells2011
- Author(s)
  Higuchi Y, Hashii M, Tanii S, Koriyama Y
- Organizer
  Redox biology and micronutrients : from signaling to translation and back
- Place of Presentation
  The marmara taksim hotel, Istanbul, Turkey
- Data Source
  KAKENHI-PROJECT-22590202
[Presentation] Reactive oxygen species-independent chromosomal giant DNA fragmentation associated with caspase-mediated apoptosis in ultraviolet-irradiated cells2011
- Author(s)
  Higuchi, Y., Hashii, M., Tanii, H., Koriyama, Y.
- Organizer
  SFRR-Europe 2011 Meeting
- Place of Presentation
  Istanbul (Turkey)
- Year and Date
  2011-09-10
- Data Source
  KAKENHI-PROJECT-22590091
[Presentation] Reactive oxygenspecies-independent chromosomal giant DNA fragmenta- tion associated with caspase-mediated apoptosis in ultraviolet -irradiated cells.2011
- Author(s)
  Higuchi, Y., Hashii, M., Tanii,H. andKoriyama,Y.
- Organizer
  SFRR-Europe 2011 Meeting
- Place of Presentation
  Istanbul
- Year and Date
  2011-09-10
- Data Source
  KAKENHI-PROJECT-22590091
[Presentation]2010
- Author(s)
  Higuchi, Y. Hashii, M., Tanii, H. and Kohriyama, Y.
- Organizer
  16th World Congress of Basic and Clinical Pharmacology
- Place of Presentation
  コペンハーゲン
- Year and Date
  2010-07-20
- Data Source
  KAKENHI-PROJECT-22590091
[Presentation] Arachidonic acid promotes glutamate-induced cell death associated with necrosis through 12-lipoxygenase activation in glioma cells.2010
- Author(s)
  Higuchi, Y.Hashii, M., Tanii, H., Kohriyama, Y.
- Organizer
  16th World Congress of Basic and Clinical Pharmacology
- Place of Presentation
  コペンハーゲン(デンマーク)
- Year and Date
  2010-07-20
- Data Source
  KAKENHI-PROJECT-22590091
[Presentation] 内側側頭葉てんかん患者の海馬硬化組織における酸化損傷タンパク質の検出と同定
- Author(s)
  古川絢子，柿田明美，千葉陽一，武井史郎，石井さなえ，河村則子，細川昌則，樋口善博，高橋均，島田厚良
- Organizer
  日本神経病理学会
- Place of Presentation
  新潟
- Data Source
  KAKENHI-PROJECT-22590091
[Presentation] 二酸化チタンナノ粒子による活性酸素を介しない細胞死誘導
- Author(s)
  樋口善博、古川絢子，高木圭子、清水宣明
- Organizer
  日本社会薬学会第31回年会
- Place of Presentation
  鈴鹿
- Data Source
  KAKENHI-PROJECT-22590091
[Presentation] 食品中に含まれる有効成分の安全性評価　その1：カテキン類のDNA損傷性
- Author(s)
  古川絢子，樋口善博，村田真理子，及川伸二，川西正祐
- Organizer
  日本社会薬学会第31回年会
- Place of Presentation
  鈴鹿
- Data Source
  KAKENHI-PROJECT-22590091
[Presentation] 紫外線誘導アポトーシスにおける染色体DNA断片化と細胞内関連因子の動態
- Author(s)
  樋口善博，古川絢子
- Organizer
  フォーラム2012：衛生薬学・環境トキシコロジー
- Place of Presentation
  名古屋
- Data Source
  KAKENHI-PROJECT-22590091
[Presentation] TiO2 particles induces apoptosis associated with chromosomal DNA fragmentation and without ROS production in L1210 leukemia cells
- Author(s)
  Higuchi,, Y., Takaki, K, Furukawa, A. and Shimizu, N.
- Organizer
  16th SFRRI Biennial Meeting, London, UK
- Place of Presentation
  ロンドン
- Data Source
  KAKENHI-PROJECT-22590091
[Presentation] Effect of zonisamide on apoptosis-related factors formed during iron-induced epileptogenesis in rat brain.
- Author(s)
  Higuchi, Y., Furukawa, A., Oowada, S., Komatsu, M. and Hiramatsu, M.,
- Organizer
  14th International Congress of Histochemistry and Cytochemistry (ICHC 2012),
- Place of Presentation
  京都市
- Data Source
  KAKENHI-PROJECT-22590091
[Presentation] Proteomic identification of oxidatively damaged proteins in　excitotoxin-induced hippocampal injury
- Author(s)
  Furukawa, A. Shimada, A. andHiguchi,
- Organizer
  14th International Congress of Histochemistry 　and Cytochemistry (ICHC 2012),
- Place of Presentation
  京都市
- Data Source
  KAKENHI-PROJECT-22590091

1. HASHI Minako (10272957)

# of Collaborated Projects: 2 results

# of Collaborated Products: 8 results
2. HIGASHIDA Haruhiro (30093066)

# of Collaborated Projects: 2 results

# of Collaborated Products: 0 results
3. MATSUKAWA Shigeru (00092809)

# of Collaborated Projects: 2 results

# of Collaborated Products: 0 results
4. YOSHIMOTO Tanihiro (60127876)

# of Collaborated Projects: 2 results

# of Collaborated Products: 0 results
5. INOUE Sumiko (20378657)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
6. TAKAHASHI Yashitaka (10236333)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
7. MURAKAMI Takashi (40210009)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
8. TANII Hideji (90110618)

# of Collaborated Projects: 1 results

# of Collaborated Products: 9 results
9. Furukawa Ayako (10455537)

# of Collaborated Projects: 1 results

# of Collaborated Products: 7 results

HIGUCHI Yoshihiro 樋口 善博

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Proteomic identification of oxidatively damaged proteins in excitotoxin-induced cell death

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Study on some proteins controling cell death in oxidative stress-induced neuronal cell death.Principal Investigator

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Activation mechanism of cyclic ADP-ribose-synthesizing enzyme CD38

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The study on the glutamate-induced glial cell death mechanism for modulation of apoptosis to necrosis by arachidonic acid-mediated lipid peroxidationPrincipal Investigator

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Pathophysiological role of lipid molecules produced by 12/l5-lipoxygenase

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Role of arachdonate cascade in apoptosis of neronal cellsPrincipal Investigator

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[Journal Article] (Review) The role of endonucleases in chromosomal DNA fragmentation associated with apoptosis and necrosis.2006

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[Journal Article] (Review) The role of endonucleases in chromosomal DNA fragmentation associated with apoptosis and necrosis.2006

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[Journal Article] The role of lipid peroxidation in chromosomal DNA frag-mentation associated with cell death induced by glutathione depletion.2006

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[Journal Article] The role of lipid peroxidation in chromosomal DNA frag-mentation associated with cell death induced by glutathione depletion.2006

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[Journal Article] (Review) Antitumor and biological effects of Streptococcus pyogenes2006

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[Journal Article] (Review) The role of lipid peroxidation in chromosomal DN frag-mentation associated with cell death induced by glutathione depletion.2005

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[Journal Article] Sulindac activates nuclear translocation of DFF40 and Endonuclease G but not induces oligonucleosomal DNA fragmentation in HT-29 cells.2005

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[Journal Article] (Review) Pathological changes induced by allylnitrile and crotononitrile: relationship with behavioral abnormalities.2005

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[Journal Article] Pathological changes induced by allylnitrile and crotononitrile : relationship with behavioral abnormalities2005

HIGUCHI Yoshihiro 樋口善博