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FUJII Satoshi  藤井 敏

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… Alternative Names

FUJII SATOSHI  藤井 敏

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Researcher Number 10107104
Other IDs
External Links
Affiliation (based on the past Project Information) *help 2012: 静岡県立大学, 薬学部, その他
2012: 静岡県立大学, 薬学部, 客員教授
2010 – 2011: 静岡県立大学, 薬学部, 教授
2002 – 2003: 静岡県立大学, 薬学部, 教授
1997 – 2000: 静岡県立大学, 薬学部, 教授 … More
1989 – 1996: 大阪大学, 薬学部, 助教授
1990: 大阪大学, 薬科部, 助教授
1986 – 1987: 大阪大学, 薬学部, 助教授
1986: 阪大, 薬学部, 助教授 Less
Review Section/Research Field
Principal Investigator
Physical pharmacy / Physical pharmacy
Except Principal Investigator
広領域
Keywords
Principal Investigator
X線構造解析 / X線解析 / インフルエンザ / ドラッグデザイン / 分子動力学計算 / DNA / 高次構造予測 / 核酸-蛋白質複合体 / 機能性核酸 / 水和 … More / 分子置換法 / Wobble塩基対 / 塩基対 / base mismatch / X-Ray determination / Cis-Pt-DNA complex / Molecular dynamic simulation / Proton NMR / DNA structure / 抗生物質の作用メカニズム / 塩基配列特異性 / 円二色性 / 核酸のコンフォメーション / Bent構造 / 塩基対ミスマッチ / X-ray / シス白金-DNA / プロトンNMR / DNAの高次構造 / drug design / crystallizability / hemagglutinin / X-ray structure / フォルデング / モルテングロービル / 薬物設計 / 結晶化 / ヘマグルチニン / Hydrolysis mechanism / Protein Crystallography / Molecular replace method / repair mechanism / alkylated base / Structure-Activity relationship / Structural based modeling / Protein-nucleic acids complex / 構造生物学 / リボザイム / 蛋白質結晶解析 / 加水分解機構 / 修復機構 / アルキル化塩基 / 構造-活性相関 / Molecular dynamics / Chromomycin / X-ray analysis / bent structure / beta-turn / DNA binding protein / ブレマイシン / 分子動力学 / クロモマイシン / 核酸ベント構造 / βーturn構造 / DNA結合蛋白質 / 金属配位様式 / 薬物送達 / X線結晶解析 / 生物物理化学 / threading / 熱安定性 / 構造精密化 / ヒト・リゾチーム / 3D-1D法 / 温度因子 / 分子設計 / A-RNA / 非古典的塩基対 / アヘーピン / ピリミジン-ピリミジン塩基対 / ヘアーピン / A型核酸 / ヘア-ピン / RNA … More
Except Principal Investigator
X線結晶構造解析 / X線結晶解析 / 塩基配列 / 核磁気共鳴(NMR) / コンホメーション / 核酸ドメイン / 酵素反応機構 / 3-メチルアデニンDNAグリコシラーゼ / DNA修復酵素 / Antigen recognition / Crystal structure / Antibody / Glycoprotein / Membrane protein / Structural biology / X-ray crystallography / Proteins / 分子生物学 / X線回折法 / 生体高分子 / 結晶構造 / 蛋白質三次元構造 / 膜蛋白質 / 構造生物学 / 三次元構造 / 結晶化 / 抗体 / 糖蛋白質 / 蛋蛋白質 / 蛋白質 / Amino acid Sequence of heavy chain in Fab / surface protein / Monoclonal antibodies against circumsporozoite / Circumsporozoite surface protein as antigen / Repeating amino acid sequence / X-ray structural studies / Malaria vaccine / 抗原・抗体複合体 / モノクロ-ナル抗体 / 融合蛋白質抗原 / マラリア原虫表皮蛋白質 / H鎖アミノ酸配列 / 抗原・抗体および抗原・抗体複合体の結晶化 / モノクロ-ナル抗体Fab / マラリア原虫表皮蛋白質抗原 / マラリアワクチン / DNA修復機構解明 / alkA遺伝子産物 / 3ーメチルアデニンDNAグリコシラーゼII / アルキル化DNA修復酵素 Less
  • Research Projects

    (17 results)
  • Research Products

    (19 results)
  • Co-Researchers

    (26 People)
  •  Basic research for development of novel switch part on conformation and delivery of nucleic acidPrincipal Investigator

    • Principal Investigator
      FUJII Satoshi
    • Project Period (FY)
      2010 – 2012
    • Research Category
      Grant-in-Aid for Scientific Research (C)
    • Research Field
      Physical pharmacy
    • Research Institution
      University of Shizuoka
  •  Dynamic structure of biological related molecules : X-ray determination and Molecular dynamic simulationPrincipal Investigator

    • Principal Investigator
      FUJII Satoshi
    • Project Period (FY)
      2002 – 2003
    • Research Category
      Grant-in-Aid for Scientific Research (C)
    • Research Field
      Physical pharmacy
    • Research Institution
      University of Shizuoka
  •  Structural bases of the functional nucleic acids as the therapeutic targetPrincipal Investigator

    • Principal Investigator
      FUJII Satoshi
    • Project Period (FY)
      1998 – 2000
    • Research Category
      Grant-in-Aid for Scientific Research (B).
    • Research Field
      Physical pharmacy
    • Research Institution
      University of Shizuoka
  •  蛋白質結晶が明らかにした揺らぎ構造とその予測Principal Investigator

    • Principal Investigator
      藤井 敏
    • Project Period (FY)
      1997
    • Research Category
      Grant-in-Aid for Scientific Research on Priority Areas
    • Research Institution
      University of Shizuoka
  •  3-メチルアデニンDNAグリコシラーゼの反応機構

    • Principal Investigator
      山縣 ゆり子
    • Project Period (FY)
      1996
    • Research Category
      Grant-in-Aid for Scientific Research on Priority Areas
    • Research Institution
      Osaka University
  •  3-メチルアデニンDNAグリコシラーゼの反応機構

    • Principal Investigator
      山縣 ゆり子
    • Project Period (FY)
      1995
    • Research Category
      Grant-in-Aid for Scientific Research on Priority Areas
    • Research Institution
      Osaka University
  •  Development of Rapid and Accurate Methods for X-ray Crystallography to Study Crystal Structures and Functions of Proteins.

    • Principal Investigator
      SATOW Yoshinori
    • Project Period (FY)
      1994 – 1995
    • Research Category
      Grant-in-Aid for Co-operative Research (A)
    • Research Field
      広領域
    • Research Institution
      University of Tokyo
  •  機能性RNA分子の原子レベルでの構造Principal Investigator

    • Principal Investigator
      藤井 敏
    • Project Period (FY)
      1993
    • Research Category
      Grant-in-Aid for Scientific Research on Priority Areas
    • Research Institution
      Osaka University
  •  機能性RNA分子のX線構造解析Principal Investigator

    • Principal Investigator
      藤井 敏
    • Project Period (FY)
      1992
    • Research Category
      Grant-in-Aid for Scientific Research on Priority Areas
    • Research Institution
      Osaka University
  •  RNA分子機能ドメインのコンフォメーション解析Principal Investigator

    • Principal Investigator
      藤井 敏
    • Project Period (FY)
      1992
    • Research Category
      Grant-in-Aid for Scientific Research on Priority Areas
    • Research Institution
      Osaka University
  •  機能性RNA分子のX線構造解析Principal Investigator

    • Principal Investigator
      藤井 敏
    • Project Period (FY)
      1991
    • Research Category
      Grant-in-Aid for Scientific Research on Priority Areas
    • Research Institution
      Osaka University
  •  アルキル化DNA修復機構の三次元構造レベルでの解明

    • Principal Investigator
      TOMITA Ken-ichi
    • Project Period (FY)
      1989
    • Research Category
      Grant-in-Aid for Cancer Research
    • Research Institution
      Osaka University
  •  X-ray Structural Studies of Antigen-Antibody Complex Toward Malaria Vaccine Development.

    • Principal Investigator
      TOMITA Ken-ichi
    • Project Period (FY)
      1989 – 1991
    • Research Category
      Grant-in-Aid for international Scientific Research
    • Research Institution
      Osaka University
  •  The Molecular Recognition Mechanism of Nucleic Acid Structure by Beta-Turn Motif of ProteinPrincipal Investigator

    • Principal Investigator
      FUJII Satoshi
    • Project Period (FY)
      1989 – 1990
    • Research Category
      Grant-in-Aid for General Scientific Research (C)
    • Research Field
      Physical pharmacy
    • Research Institution
      Osaka University
  •  Structual Studies for Nucleic Acids Conformation as Genetic Signal and Regulational SignalPrincipal Investigator

    • Principal Investigator
      FUJII SATOSHI
    • Project Period (FY)
      1986 – 1987
    • Research Category
      Grant-in-Aid for General Scientific Research (B)
    • Research Field
      Physical pharmacy
    • Research Institution
      FACULTY OF PHARMACEUTICAL SCIENCES, OSAKA UNIVERSITY
  •  核酸ドメインのコンホメーション解析

    • Principal Investigator
      大井 龍夫
    • Project Period (FY)
      1985 – 1986
    • Research Category
      Grant-in-Aid for Special Project Research
    • Research Institution
      Kyoto University
  •  核酸ドメインのコンホメーション解析

    • Principal Investigator
      大井 龍夫
    • Project Period (FY)
      1985 – 1987
    • Research Category
      Grant-in-Aid for Special Project Research
    • Research Institution
      Kyoto University

All 2013 2012 2011 2010

All Journal Article Presentation

  • [Journal Article] Regiocomplementary Cycloaddition Reactions of Boryl- and Silylbenzynes with 1, 3-Dipoles : Selective Synthesis of Benzo-Fused Azole Derivatives2013

    • Author(s)
      Akira Takagi, Takashi Ikawa, Alcira Takagi, Masahiko Goto, Yuya Aoyama, Yoshinobu Ishikawa, Yuji Itoh, Hiroaki Tokiwa, and Shuji Akai
    • Journal Title

      The Journal of Organic Chemistry

      Volume: 78 Issue: 7 Pages: 2965-2983

    • DOI

      10.1021/jo302802b

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-11J10892, KAKENHI-PROJECT-22590039, KAKENHI-PROJECT-23790017, KAKENHI-PROJECT-24590141, KAKENHI-PROJECT-25460018, KAKENHI-PROJECT-25460157
  • [Journal Article] A new crystal lattice structure of Helicobactor pylori neutrophil- activating protein (HP-NAP)2012

    • Author(s)
      O.Tsuruta, H.Yokoyama, S.Fujii
    • Journal Title

      Acta Cryst

      Volume: F68 Pages: 134-140

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-22590039
  • [Journal Article] Novel candesartan derivatives as indoleamine 2, 3-dioxygenase inhibitors2012

    • Author(s)
      Matsuno K, Yamazaki H, Isaka Y, takai K, Unno Y, Ogo N, Ishikawa Y, Fujii S, Takikawa O, Asai A
    • Journal Title

      Med. Chem. Comm.

      Volume: 3 Issue: 4 Pages: 475-479

    • DOI

      10.1039/c2md00278g

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-21590353, KAKENHI-PROJECT-22590039, KAKENHI-PROJECT-24590141
  • [Journal Article] A new crystal lattice structure of Helico-bactor pylori neutrophil-activating protein(HP-NAP)2012

    • Author(s)
      O.Tsuruta,H.Yokoyama,S.Fujii
    • Journal Title

      Acta Cryst.

      Volume: F68巻 Pages: 134-140

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-22590039
  • [Journal Article] Crystal structure of Helicobacter pylori neutrophil-activating protein with a di-nuclear ferroxidase center in a zinc or cadmium-bound form2012

    • Author(s)
      H. Yokoyama, O. Tsuruta, N. Akao, S. Fujii
    • Journal Title

      Biochem. Biophys. Res. Comm.

      Volume: 422 Issue: 4 Pages: 745-750

    • DOI

      10.1016/j.bbrc.2012.05.073

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-22590039
  • [Journal Article] Crystal Structure of a Membrane Stomatin-Specific Protease in Complex with a Substrate Peptide2012

    • Author(s)
      H.Yokoyama,N.Takizawa,D.Kobayashi, I.Matsui, S.Fujii
    • Journal Title

      Biochemistry

      Volume: 51巻 Issue: 18 Pages: 3872-3880

    • DOI

      10.1021/bi300098k

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-22590039
  • [Journal Article] ortho-Selective Nucleophilic Addition of Primary Amines to Silylbenzynes : Synthes is of 2-Silylanilines2011

    • Author(s)
      T.Ikawa, T.Nishiyama, T.Shigeta, S.Mohri, S.Morita, S.Takayanagi, Y.Terauchi, Y.Morikawa, A.Takagi, Y.Ishikawa, S.Fujii, Y.Kita, S.Akai
    • Journal Title

      Angew.Chem.Int.Ed.

      Volume: 50 Pages: 5674-5677

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-22590039
  • [Journal Article] Binding mode prediction and inhibitor design of anti-influenza virus diketo acids targeting metalloenzyme RNA polymerase by molecular docking2011

    • Author(s)
      Y.Ishikawa, S.Fujii
    • Journal Title

      Bioinformation

      Volume: 6 Pages: 221-225

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-22590039
  • [Journal Article] ortho-Selective Nucleophilic ddition of Primary Amines to Silylbenzynes: Synthesis of 2-Silylanilines2011

    • Author(s)
      T. Ikawa, T. Nishiyama, T. Shigeta, S. Mohri, S. Morita, S. Takayanagi, Y. Terauchi, Y. Morikawa, A. Takagi, Y. Ishikawa, S. Fujii, Y. Kita, S. Akai
    • Journal Title

      Angew. Chem. Int. Ed.

      Volume: 50巻 Pages: 5674-5677

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-22590039
  • [Journal Article] Binding mode prediction and inhibitor design of anti-influenza virus diketo acids targeting metalloenzyme RNA polymer-rase by molecular docking2011

    • Author(s)
      Y.Ishikawa,S.Fujii
    • Journal Title

      Bioinfor-mation

      Volume: 6巻 Pages: 221-225

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-22590039
  • [Journal Article] Binding of sulphatide to recombinant haemagglutinin of influenza A virus produced by a baculovirus protein expression system.2010

    • Author(s)
      T.Takahashi, H.Satoh, M.Takaguchi, S.Takafuji, H.Yokoyama, S.Fujii, T Suzuki
    • Journal Title

      J.Biochem.

      Volume: 147 Pages: 459-462

    • NAID

      10027874834

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-22590039
  • [Journal Article] Structural study for the neutrophil-activating protein from Helicobacter pylori2010

    • Author(s)
      H.Yokoyama, O.Tsuruta, N.Akao, S.Fujii
    • Journal Title

      Photon Factory Activity Report 2009

      Volume: 27 Pages: 226-226

    • Data Source
      KAKENHI-PROJECT-22590039
  • [Journal Article] 1,1',1",1"'-[Porphyrin-5,10,15,20-tetrayltetrakis(3,1-phenylenemethylene)]tetraquinolinium etrabromide2010

    • Author(s)
      Y.Ishikawa, T.Yamashita, S.Fujii, T. Uno
    • Journal Title

      Molbank

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-22590039
  • [Journal Article] 1,1',1",1"'-[Porphyrin-5, 10, 15, 20-tetrayltetrakis(3,1-phenylenemethylene)]tetraquinolinium Tetrabromide.2010

    • Author(s)
      Y.Ishikawa, T.Yamashita, S.Fujii, T Uno
    • Journal Title

      Molbank

      Volume: 2010

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-22590039
  • [Journal Article] Binding of sulphatide to recombinant haemagglutinin of influenza A virus produced by a baculovirus protein expression system2010

    • Author(s)
      T.Takahashi, H.Satoh, M.Takaguchi, S.Takafuji, H.Yokoyama, S. Fujii, T. Suzuki
    • Journal Title

      J. Biochem.

      Volume: 147巻 Pages: 459-462

    • NAID

      10027874834

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-22590039
  • [Journal Article] Structural study for the neutrophil-activating protein from Helicobacter pylori2010

    • Author(s)
      H.Yokoyama, O.Tsuruta, N.Akao, S.Fujii
    • Journal Title

      Photon Factory Activity Report2009

      Volume: 27巻 Pages: 226-226

    • Data Source
      KAKENHI-PROJECT-22590039
  • [Presentation] A new crystal lattice structure of Helicobactor pylori neutrophil-activating protein(HP-NAP)2011

    • Author(s)
      Tsuruta, H.Yokoyama, S.Fujii
    • Organizer
      国際結晶学会
    • Place of Presentation
      スペイン(マドリッド)
    • Year and Date
      2011-08-23
    • Data Source
      KAKENHI-PROJECT-22590039
  • [Presentation] ヘリコバクターピロリ好中球活性化タンパク質による金属イオンの貯蔵・放出の構造基盤~金属注入法の違いによる配位様式の差異~2011

    • Author(s)
      鶴田修,横山英志,藤井敏
    • Organizer
      日本薬学会第131年会
    • Place of Presentation
      静岡
    • Year and Date
      2011-03-29
    • Data Source
      KAKENHI-PROJECT-22590039
  • [Presentation] A new crystal lattice structure of Helicobactor pylori neutrophil- activating protein (HP-NAP)2011

    • Author(s)
      O.Tsuruta, H.Yokoyama, S.Fujii
    • Organizer
      国際結晶学会
    • Place of Presentation
      スペイン(マドリッド)
    • Year and Date
      2011-08-23
    • Data Source
      KAKENHI-PROJECT-22590039
  • 1.  YAMAGATA Yuriko (40183678)
    # of Collaborated Projects: 8 results
    # of Collaborated Products: 0 results
  • 2.  TOMITA Ken-ichi (30028831)
    # of Collaborated Projects: 3 results
    # of Collaborated Products: 0 results
  • 3.  HAKOSHIMA. Toshio (00164773)
    # of Collaborated Projects: 2 results
    # of Collaborated Products: 0 results
  • 4.  西川 一八 (60109262)
    # of Collaborated Projects: 2 results
    # of Collaborated Products: 0 results
  • 5.  神藤 平三郎 (80138966)
    # of Collaborated Projects: 2 results
    # of Collaborated Products: 0 results
  • 6.  磯野 克己 (70011640)
    # of Collaborated Projects: 2 results
    # of Collaborated Products: 0 results
  • 7.  京極 好正 (90012632)
    # of Collaborated Projects: 2 results
    # of Collaborated Products: 0 results
  • 8.  YOKOYAMA Hideshi (70433208)
    # of Collaborated Projects: 1 results
    # of Collaborated Products: 11 results
  • 9.  HORII Toshihiro (80142305)
    # of Collaborated Projects: 1 results
    # of Collaborated Products: 0 results
  • 10.  OMATA Yoshitaka (10132987)
    # of Collaborated Projects: 1 results
    # of Collaborated Products: 0 results
  • 11.  UESUGI Seiichi (70028851)
    # of Collaborated Projects: 1 results
    # of Collaborated Products: 0 results
  • 12.  SATOW Yoshinori (30150014)
    # of Collaborated Projects: 1 results
    # of Collaborated Products: 0 results
  • 13.  FUKUYAMA Keiichi (80032283)
    # of Collaborated Projects: 1 results
    # of Collaborated Products: 0 results
  • 14.  TSUKIHARA Tomitake (00032277)
    # of Collaborated Projects: 1 results
    # of Collaborated Products: 0 results
  • 15.  MIKI Kunio (10116105)
    # of Collaborated Projects: 1 results
    # of Collaborated Products: 0 results
  • 16.  TANAKA Isao (70093052)
    # of Collaborated Projects: 1 results
    # of Collaborated Products: 0 results
  • 17.  TANAKA Nobuo (50032024)
    # of Collaborated Projects: 1 results
    # of Collaborated Products: 0 results
  • 18.  大井 龍夫 (00027012)
    # of Collaborated Projects: 1 results
    # of Collaborated Products: 0 results
  • 19.  大井 龍夫 (00027004)
    # of Collaborated Projects: 1 results
    # of Collaborated Products: 0 results
  • 20.  山根 隆 (80030055)
    # of Collaborated Projects: 1 results
    # of Collaborated Products: 0 results
  • 21.  ARMAH George E.
    # of Collaborated Projects: 1 results
    # of Collaborated Products: 0 results
  • 22.  POLJAK Roberto J.
    # of Collaborated Projects: 1 results
    # of Collaborated Products: 0 results
  • 23.  AKANMORI Bar
    # of Collaborated Projects: 1 results
    # of Collaborated Products: 0 results
  • 24.  AKANMORI Barthoromew D.
    # of Collaborated Projects: 1 results
    # of Collaborated Products: 0 results
  • 25.  POLJAK Robe
    # of Collaborated Projects: 1 results
    # of Collaborated Products: 0 results
  • 26.  滝川 修
    # of Collaborated Projects: 0 results
    # of Collaborated Products: 1 results

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