FUJII Satoshi 藤井敏

Researcher Number	10107104
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Affiliation *help	2016 – 2018 : 静岡県立大学, 薬学部, 客員教授 2012 : 静岡県立大学, 薬学部, その他 2012 : 静岡県立大学, 薬学部, 客員教授 2010 – 2011 : 静岡県立大学, 薬学部, 教授 2002 – 2003 : 静岡県立大学, 薬学部, 教授 … More
Review Section/Research Field	Principal Investigator Physical pharmacy / Physical pharmacy Except Principal Investigator 広領域
Keywords	Principal Investigator X線構造解析 / X線解析 / インフルエンザ / 水和 / Wobble塩基対 / 高次構造予測 / 機能性核酸 / 塩基対 / DNA / 分子動力学計算 … More Except Principal Investigator X線結晶構造解析 / 核磁気共鳴(NMR) / コンホメーション / X線結晶解析 / 塩基配列 / 酵素反応機構 / DNA修復酵素 / 核酸ドメイン / 3-メチルアデニンDNAグリコシラーゼ / 三次元構造 / 分子生物学 / 結晶化 / マラリア原虫表皮蛋白質 / Structural biology / alkA遺伝子産物 / モノクロ-ナル抗体Fab / 構造生物学 / Circumsporozoite surface protein as antigen / 糖蛋白質 / X-ray structural studies / Repeating amino acid sequence / Malaria vaccine / モノクロ-ナル抗体 / H鎖アミノ酸配列 / 抗原・抗体および抗原・抗体複合体の結晶化 / Monoclonal antibodies against circumsporozoite / Glycoprotein / Amino acid Sequence of heavy chain in Fab / Proteins / 3ーメチルアデニンDNAグリコシラーゼII / マラリア原虫表皮蛋白質抗原 / 膜蛋白質 / Antigen recognition / DNA修復機構解明 / X-ray crystallography / アルキル化DNA修復酵素 / マラリアワクチン / Crystal structure / 生体高分子 / Membrane protein / 蛋蛋白質 / X線回折法 / surface protein / 抗原・抗体複合体 / 蛋白質三次元構造 / Antibody / 抗体 / 結晶構造 / 蛋白質 / 融合蛋白質抗原 Less

Basic research for development of novel switch part on conformation and delivery of nucleic acidPrincipal Investigator
- Principal Investigator
  
  FUJII Satoshi
- Project Period (FY)
  2010 – 2012
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Research Field
  
  Physical pharmacy
- Research Institution
  University of Shizuoka
Dynamic structure of biological related molecules : X-ray determination and Molecular dynamic simulationPrincipal Investigator
- Principal Investigator
  
  FUJII Satoshi
- Project Period (FY)
  2002 – 2003
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Research Field
  
  Physical pharmacy
- Research Institution
  University of Shizuoka
Structural bases of the functional nucleic acids as the therapeutic targetPrincipal Investigator
- Principal Investigator
  
  FUJII Satoshi
- Project Period (FY)
  1998 – 2000
- Research Category
  
  Grant-in-Aid for Scientific Research (B).
- Research Field
  
  Physical pharmacy
- Research Institution
  University of Shizuoka
蛋白質結晶が明らかにした揺らぎ構造とその予測Principal Investigator
- Principal Investigator
  
  藤井敏
- Project Period (FY)
  1997
- Research Category
  
  Grant-in-Aid for Scientific Research on Priority Areas
- Research Institution
  University of Shizuoka
3-メチルアデニンDNAグリコシラーゼの反応機構
- Principal Investigator
  
  山縣ゆり子
- Project Period (FY)
  1996
- Research Category
  
  Grant-in-Aid for Scientific Research on Priority Areas
- Research Institution
  Osaka University
3-メチルアデニンDNAグリコシラーゼの反応機構
- Principal Investigator
  
  山縣ゆり子
- Project Period (FY)
  1995
- Research Category
  
  Grant-in-Aid for Scientific Research on Priority Areas
- Research Institution
  Osaka University
Development of Rapid and Accurate Methods for X-ray Crystallography to Study Crystal Structures and Functions of Proteins.
- Principal Investigator
  
  SATOW Yoshinori
- Project Period (FY)
  1994 – 1995
- Research Category
  
  Grant-in-Aid for Co-operative Research (A)
- Research Field
  
  広領域
- Research Institution
  University of Tokyo
機能性RNA分子の原子レベルでの構造Principal Investigator
- Principal Investigator
  
  藤井敏
- Project Period (FY)
  1993
- Research Category
  
  Grant-in-Aid for Scientific Research on Priority Areas
- Research Institution
  Osaka University
機能性RNA分子のX線構造解析Principal Investigator
- Principal Investigator
  
  藤井敏
- Project Period (FY)
  1992
- Research Category
  
  Grant-in-Aid for Scientific Research on Priority Areas
- Research Institution
  Osaka University
RNA分子機能ドメインのコンフォメーション解析Principal Investigator
- Principal Investigator
  
  藤井敏
- Project Period (FY)
  1992
- Research Category
  
  Grant-in-Aid for Scientific Research on Priority Areas
- Research Institution
  Osaka University
機能性RNA分子のX線構造解析Principal Investigator
- Principal Investigator
  
  藤井敏
- Project Period (FY)
  1991
- Research Category
  
  Grant-in-Aid for Scientific Research on Priority Areas
- Research Institution
  Osaka University
アルキル化DNA修復機構の三次元構造レベルでの解明
- Principal Investigator
  
  TOMITA Ken-ichi
- Project Period (FY)
  1989
- Research Category
  
  Grant-in-Aid for Cancer Research
- Research Institution
  Osaka University
X-ray Structural Studies of Antigen-Antibody Complex Toward Malaria Vaccine Development.
- Principal Investigator
  
  TOMITA Ken-ichi
- Project Period (FY)
  1989 – 1991
- Research Category
  
  Grant-in-Aid for international Scientific Research
- Research Institution
  Osaka University
The Molecular Recognition Mechanism of Nucleic Acid Structure by Beta-Turn Motif of ProteinPrincipal Investigator
- Principal Investigator
  
  FUJII Satoshi
- Project Period (FY)
  1989 – 1990
- Research Category
  
  Grant-in-Aid for General Scientific Research (C)
- Research Field
  
  Physical pharmacy
- Research Institution
  Osaka University
Structual Studies for Nucleic Acids Conformation as Genetic Signal and Regulational SignalPrincipal Investigator
- Principal Investigator
  
  FUJII SATOSHI
- Project Period (FY)
  1986 – 1987
- Research Category
  
  Grant-in-Aid for General Scientific Research (B)
- Research Field
  
  Physical pharmacy
- Research Institution
  FACULTY OF PHARMACEUTICAL SCIENCES, OSAKA UNIVERSITY
核酸ドメインのコンホメーション解析
- Principal Investigator
  
  大井龍夫
- Project Period (FY)
  1985 – 1986
- Research Category
  
  Grant-in-Aid for Special Project Research
- Research Institution
  Kyoto University
核酸ドメインのコンホメーション解析
- Principal Investigator
  
  大井龍夫
- Project Period (FY)
  1985 – 1987
- Research Category
  
  Grant-in-Aid for Special Project Research
- Research Institution
  Kyoto University

All 2013 2012 2011 2010

All Journal Article Presentation

[Journal Article] Regiocomplementary ycloaddi-tion Reactions of Boryl-and Silylben-zynes with 1,3-Dipoles: Selective Synthesis of Benzo-Fused Azole Derivatives2013
- Author(s)
  Akira Takagi, Takashi Ikawa, Alcira Takagi, Masahiko Goto, Yuya Aoyama, Yoshinobu Ishikawa, Yuji Itoh, Hiroaki Tokiwa, and Shuji Akai
- Journal Title
  
  J. Org. Chem.
  
  Volume : 78 Pages : 2965-2983
- DOI
  10.1021/jo302802b
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-11J10892, KAKENHI-PROJECT-22590039, KAKENHI-PROJECT-23790017, KAKENHI-PROJECT-24590141, KAKENHI-PROJECT-25460018, KAKENHI-PROJECT-25460157
[Journal Article] Crystal structure of Helicobacter pylori neutrophil-activating protein with a di-nuclear ferroxidase center in a zinc or cadmium-bound form2012
- Author(s)
  H. Yokoyama, O. Tsuruta, N. Akao, S. Fujii
- Journal Title
  
  Biochem. Biophys. Res. Comm.
  
  Volume : 422 Pages : 745-750
- DOI
  10.1016/j.bbrc.2012.05.073
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-22590039
[Journal Article] Crystal Structure of a Membrane Stomatin-Specific Protease in Complex with a Substrate Peptide2012
- Author(s)
  H.Yokoyama,N.Takizawa,D.Kobayashi, I.Matsui, S.Fujii
- Journal Title
  
  Biochemistry
  
  Volume : 51巻 Pages : 3872-3880
- DOI
  10.1021/bi300098k
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-22590039
[Journal Article] A new crystal lattice structure of Helico-bactor pylori neutrophil-activating protein(HP-NAP)2012
- Author(s)
  O.Tsuruta,H.Yokoyama,S.Fujii
- Journal Title
  
  Acta Cryst.
  
  Volume : F68巻 Pages : 134-140
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-22590039
[Journal Article] A new crystal lattice structure of Helicobactor pylori neutrophil- activating protein (HP-NAP)2012
- Author(s)
  O.Tsuruta, H.Yokoyama, S.Fujii
- Journal Title
  
  Acta Cryst
  
  Volume : F68 Pages : 134-140
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-22590039
[Journal Article] Novel candesartan derivatives as indole-amine-2,3-dioxygenase inhibitors2012
- Author(s)
  Matsuno K, Yamazaki H, Isaka Y, takai K, Unno Y, Ogo N, Ishikawa Y, Fujii S, Takikawa O, Asai A
- Journal Title
  
  Med. Chem. Commun.
  
  Volume : 3 Pages : 475-479
- DOI
  10.1039/c2md00278g
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-21590353, KAKENHI-PROJECT-22590039, KAKENHI-PROJECT-24590141
[Journal Article] Binding mode prediction and inhibitor design of anti-influenza virus diketo acids targeting metalloenzyme RNA polymerase by molecular docking2011
- Author(s)
  Y.Ishikawa, S.Fujii
- Journal Title
  
  Bioinformation
  
  Volume : 6 Pages : 221-225
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-22590039
[Journal Article] ortho-Selective Nucleophilic Addition of Primary Amines to Silylbenzynes : Synthes is of 2-Silylanilines2011
- Author(s)
  T.Ikawa, T.Nishiyama, T.Shigeta, S.Mohri, S.Morita, S.Takayanagi, Y.Terauchi, Y.Morikawa, A.Takagi, Y.Ishikawa, S.Fujii, Y.Kita, S.Akai
- Journal Title
  
  Angew.Chem.Int.Ed.
  
  Volume : 50 Pages : 5674-5677
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-22590039
[Journal Article] ortho-Selective Nucleophilic ddition of Primary Amines to Silylbenzynes: Synthesis of 2-Silylanilines2011
- Author(s)
  T. Ikawa, T. Nishiyama, T. Shigeta, S. Mohri, S. Morita, S. Takayanagi, Y. Terauchi, Y. Morikawa, A. Takagi, Y. Ishikawa, S. Fujii, Y. Kita, S. Akai
- Journal Title
  
  Angew. Chem. Int. Ed.
  
  Volume : 50巻 Pages : 5674-5677
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-22590039
[Journal Article] Binding mode prediction and inhibitor design of anti-influenza virus diketo acids targeting metalloenzyme RNA polymer-rase by molecular docking2011
- Author(s)
  Y.Ishikawa,S.Fujii
- Journal Title
  
  Bioinfor-mation
  
  Volume : 6巻 Pages : 221-225
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-22590039
[Journal Article] Binding of sulphatide to recombinant haemagglutinin of influenza A virus produced by a baculovirus protein expression system2010
- Author(s)
  T.Takahashi, H.Satoh, M.Takaguchi, S.Takafuji, H.Yokoyama, S. Fujii, T. Suzuki
- Journal Title
  
  J. Biochem.
  
  Volume : 147巻 Pages : 459-462
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-22590039
[Journal Article] 1,1',1",1"'-[Porphyrin-5,10,15,20-tetrayltetrakis(3,1-phenylenemethylene)]tetraquinolinium etrabromide2010
- Author(s)
  Y.Ishikawa, T.Yamashita, S.Fujii, T. Uno
- Journal Title
  
  Molbank
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-22590039
[Journal Article] 1,1',1",1"'-[Porphyrin-5, 10, 15, 20-tetrayltetrakis(3,1-phenylenemethylene)]tetraquinolinium Tetrabromide.2010
- Author(s)
  Y.Ishikawa, T.Yamashita, S.Fujii, T Uno
- Journal Title
  
  Molbank
  
  Volume : 2010
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-22590039
[Journal Article] Structural study for the neutrophil-activating protein from Helicobacter pylori2010
- Author(s)
  H.Yokoyama, O.Tsuruta, N.Akao, S.Fujii
- Journal Title
  
  Photon Factory Activity Report 2009
  
  Volume : 27 Pages : 226-226
- Data Source
  KAKENHI-PROJECT-22590039
[Journal Article] Binding of sulphatide to recombinant haemagglutinin of influenza A virus produced by a baculovirus protein expression system.2010
- Author(s)
  T.Takahashi, H.Satoh, M.Takaguchi, S.Takafuji, H.Yokoyama, S.Fujii, T Suzuki
- Journal Title
  
  J.Biochem.
  
  Volume : 147 Pages : 459-462
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-22590039
[Journal Article] Structural study for the neutrophil-activating protein from Helicobacter pylori2010
- Author(s)
  H.Yokoyama, O.Tsuruta, N.Akao, S.Fujii
- Journal Title
  
  Photon Factory Activity Report2009
  
  Volume : 27巻 Pages : 226-226
- Data Source
  KAKENHI-PROJECT-22590039
[Presentation] A new crystal lattice structure of Helicobactor pylori neutrophil- activating protein (HP-NAP)2011
- Author(s)
  O.Tsuruta, H.Yokoyama, S.Fujii
- Organizer
  国際結晶学会
- Place of Presentation
  スペイン(マドリッド)
- Year and Date
  2011-08-23
- Data Source
  KAKENHI-PROJECT-22590039
[Presentation] ヘリコバクターピロリ好中球活性化タンパク質による金属イオンの貯蔵・放出の構造基盤～金属注入法の違いによる配位様式の差異～2011
- Author(s)
  鶴田修,横山英志,藤井敏
- Organizer
  日本薬学会第131年会
- Place of Presentation
  静岡
- Year and Date
  2011-03-29
- Data Source
  KAKENHI-PROJECT-22590039
[Presentation] A new crystal lattice structure of Helicobactor pylori neutrophil-activating protein(HP-NAP)2011
- Author(s)
  Tsuruta, H.Yokoyama, S.Fujii
- Organizer
  国際結晶学会
- Place of Presentation
  スペイン(マドリッド)
- Year and Date
  2011-08-23
- Data Source
  KAKENHI-PROJECT-22590039

1. YAMAGATA Yuriko (40183678)

# of Collaborated Projects : 8results

# of Collaborated Products : 0results
2. TOMITA Ken-ichi (30028831)

# of Collaborated Projects : 3results

# of Collaborated Products : 0results
3. HAKOSHIMA. Toshio (00164773)

# of Collaborated Projects : 2results

# of Collaborated Products : 0results
4. 西川一八 (60109262)

# of Collaborated Projects : 2results

# of Collaborated Products : 0results
5. 神藤平三郎 (80138966)

# of Collaborated Projects : 2results

# of Collaborated Products : 0results
6. 磯野克己 (70011640)

# of Collaborated Projects : 2results

# of Collaborated Products : 0results
7. 京極好正 (90012632)

# of Collaborated Projects : 2results

# of Collaborated Products : 0results
8. YOKOYAMA Hideshi (70433208)

# of Collaborated Projects : 1results

# of Collaborated Products : 11results
9. HORII Toshihiro (80142305)

# of Collaborated Projects : 1results

# of Collaborated Products : 0results
10. OMATA Yoshitaka (10132987)

# of Collaborated Projects : 1results

# of Collaborated Products : 0results
11. UESUGI Seiichi (70028851)

# of Collaborated Projects : 1results

# of Collaborated Products : 0results
12. SATOW Yoshinori (30150014)

# of Collaborated Projects : 1results

# of Collaborated Products : 0results
13. FUKUYAMA Keiichi (80032283)

# of Collaborated Projects : 1results

# of Collaborated Products : 0results
14. TSUKIHARA Tomitake (00032277)

# of Collaborated Projects : 1results

# of Collaborated Products : 0results
15. MIKI Kunio (10116105)

# of Collaborated Projects : 1results

# of Collaborated Products : 0results
16. TANAKA Isao (70093052)

# of Collaborated Projects : 1results

# of Collaborated Products : 0results
17. TANAKA Nobuo (50032024)

# of Collaborated Projects : 1results

# of Collaborated Products : 0results
18. 大井龍夫 (00027012)

# of Collaborated Projects : 1results

# of Collaborated Products : 0results
19. 大井龍夫 (00027004)

# of Collaborated Projects : 1results

# of Collaborated Products : 0results
20. 山根隆 (80030055)

# of Collaborated Projects : 1results

# of Collaborated Products : 0results
21. ARMAH George E.

# of Collaborated Projects : 1results

# of Collaborated Products : 0results
22. POLJAK Roberto J.

# of Collaborated Projects : 1results

# of Collaborated Products : 0results
23. AKANMORI Bar

# of Collaborated Projects : 1results

# of Collaborated Products : 0results
24. AKANMORI Barthoromew D.

# of Collaborated Projects : 1results

# of Collaborated Products : 0results
25. POLJAK Robe

# of Collaborated Projects : 1results

# of Collaborated Products : 0results
26. IKAWA TAKASHI

# of Collaborated Projects : 0results

# of Collaborated Products : 1results
27. 石川吉伸

# of Collaborated Projects : 0results

# of Collaborated Products : 2results
28. 常盤広明

# of Collaborated Projects : 0results

# of Collaborated Products : 1results
29. 滝川修

# of Collaborated Projects : 0results

# of Collaborated Products : 1results

FUJII Satoshi 藤井 敏

Research Projects

Research Products

Co-Researchers

Basic research for development of novel switch part on conformation and delivery of nucleic acidPrincipal Investigator

Principal Investigator

Project Period (FY)

Research Category

Research Field

Research Institution

Dynamic structure of biological related molecules : X-ray determination and Molecular dynamic simulationPrincipal Investigator

Principal Investigator

Project Period (FY)

Research Category

Research Field

Research Institution

Structural bases of the functional nucleic acids as the therapeutic targetPrincipal Investigator

Principal Investigator

Project Period (FY)

Research Category

Research Field

Research Institution

蛋白質結晶が明らかにした揺らぎ構造とその予測Principal Investigator

Principal Investigator

Project Period (FY)

Research Category

Research Institution

3-メチルアデニンDNAグリコシラーゼの反応機構

Principal Investigator

Project Period (FY)

Research Category

Research Institution

3-メチルアデニンDNAグリコシラーゼの反応機構

Principal Investigator

Project Period (FY)

Research Category

Research Institution

Development of Rapid and Accurate Methods for X-ray Crystallography to Study Crystal Structures and Functions of Proteins.

Principal Investigator

Project Period (FY)

Research Category

Research Field

Research Institution

機能性RNA分子の原子レベルでの構造Principal Investigator

Principal Investigator

Project Period (FY)

Research Category

Research Institution

機能性RNA分子のX線構造解析Principal Investigator

Principal Investigator

Project Period (FY)

Research Category

Research Institution

RNA分子機能ドメインのコンフォメーション解析Principal Investigator

Principal Investigator

Project Period (FY)

Research Category

Research Institution

機能性RNA分子のX線構造解析Principal Investigator

Principal Investigator

Project Period (FY)

Research Category

Research Institution

アルキル化DNA修復機構の三次元構造レベルでの解明

Principal Investigator

Project Period (FY)

Research Category

Research Institution

X-ray Structural Studies of Antigen-Antibody Complex Toward Malaria Vaccine Development.

Principal Investigator

Project Period (FY)

Research Category

Research Institution

The Molecular Recognition Mechanism of Nucleic Acid Structure by Beta-Turn Motif of ProteinPrincipal Investigator

Principal Investigator

Project Period (FY)

Research Category

Research Field

Research Institution

Structual Studies for Nucleic Acids Conformation as Genetic Signal and Regulational SignalPrincipal Investigator

FUJII Satoshi 藤井敏