HOBARA Tatsuya 芳原達也

Researcher Number	10116501
Other IDs
External Links
Affiliation (based on the past Project Information) *help	1998 – 2004: 山口大学, 医学部, 教授 1988 – 1994: Yamaguchi University School of Medicine, Professor, 医学部, 教授 1987: 山口大学, 医学部, 助教授
Review Section/Research Field	Principal Investigator 公衆衛生学 / Hygiene Except Principal Investigator Hygiene / Public health/Health science / 公衆衛生学
Keywords	Principal Investigator トリクロロエチレン / テトラクロロエチレン / トリハロメタン / 有機溶剤 / 神経細胞 / neuron / Fluo-3 / 1.1.1ートリクロロエタン / 閉塞性腸管吸収システム / 抱合型トリクロロエタノ-ル … More Except Principal Investigator 有機溶剤 / トリクロロエチレン / 細胞内カルシウム / カルシウムイオン / Fluo-3 / ブロモプロパン / trichloroethylene / bromopropane / single cell gel electrophoresis / DNA / 8-OHdG / dt / 血管平滑筋 / Fura-2 / カルシウムチャネル / 急性毒性 / 細胞内カルシウムイオン濃度 / 平滑筋収縮作用 / 血圧低下 / 亜鉛熱 / スーパーオキシド / 好中球 / マクロファージ / 細胞内情報伝達経路 / カルシウム / プロテインキナーゼC / チロシンタンパクキナーゼ / 細胞内情報伝達機構 / グルタチオン / チロシンキナーゼ / 亜鉛 / 水酸化亜鉛 / 酸化亜鉛 / 細胞内情報伝達 / プロティンキナーゼC / 受容体 / Zinc fume fever / Superoxide / Neutrophil / Macrophage / Intracellular signal transduction pathway / Calcium / Protein kinase C / Tyrosine protein kinase / 神経細胞 / パッチクランプ / 有機塩素系化合物 / ブルモプロパン / カルシウムチャンネル / 細胞内カルシウムイオン / 脊髄後根神経節 / 海馬 / プロモプロパン / イオンチャンネル / neuron / patch clump / calcium ion / organic solvents / chlorinatedhydrocarbons / ノニルフェノール / オクチルフェノール / 環境ホルモン / エストロゲン受容体 / アンドロゲン受容体 / 脳 / 性分化 / 性ステロイドホルモン / アロマテース / 内側視索前野 / 内側扁桃体 / 分界条床核 / ビスフェノールA / octylphenol / nonylphenol / endocrine disrupter / sexual differentiation / estrogen receptor / androgen receptor / brain / sex steroid / コメットアッセイ / アポトーシス / 中毒学 / ラット / 精巣 / DNA損傷 / single gel electrophoresis / 精原細胞 / 温度 / Syber Green / comet assay / apoptosis / toxicology / 1,1,1ーtrichloroethane / 循環障害 / 心収縮能 / peak dp@dt / 心拍数 / 直接作用 / 急性暴露 / peak dp / 閾値 / 量反応関係 / LLI-Tricbloroethane / Organic solvents / 1, 1, 1-Trichloroethane / Circulatory disorders / Left ventricular contractility / Peak dp Less

Research Projects
(10 results)
Co-Researchers
(9 People)

Evaluation method for DNA damage and dysfunction of spermatogenic cells due to Bromopropanes
- Principal Investigator
  
  OKUDA Masayuki
- Project Period (FY)
  2002 – 2004
- Research Category
  
  Grant-in-Aid for Scientific Research (B)
- Research Field
  
  Hygiene
- Research Institution
  Yamaguchi University
Investigation of mechanism of central nervous system disorder due to chlorinatedPrincipal Investigator
- Principal Investigator
  
  HOBARA Tatsuya
- Project Period (FY)
  2000 – 2002
- Research Category
  
  Grant-in-Aid for Scientific Research (B)
- Research Field
  
  Hygiene
- Research Institution
  Yamaguchi University
Effects of exogenous endocrine-disrupters on the brain regions related to sexual differentiation and aggressive behavior
- Principal Investigator
  
  SHINODA Koh
- Project Period (FY)
  2000 – 2001
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Research Institution
  Yamaguchi University
血管平滑筋における毒性評価方法の展開-有機塩素系化合物の血圧低下機序解明-
- Principal Investigator
  
  OKUDA Masayuki
- Project Period (FY)
  1999 – 2000
- Research Category
  
  Grant-in-Aid for Exploratory Research
- Research Field
  
  Hygiene
- Research Institution
  Yamaguchi University
Investigation of mechanism of central nervous system disorder due to chlorinated hydrocarbons
- Principal Investigator
  
  OKUDA Masayuki
- Project Period (FY)
  1999 – 2001
- Research Category
  
  Grant-in-Aid for Scientific Research (B)
- Research Field
  
  Hygiene
- Research Institution
  Yamaguchi University
Evaluation of neural toxicity of organic solvents using primary culture neuronsPrincipal Investigator
- Principal Investigator
  
  HOBARA Tatsuya
- Project Period (FY)
  1998 – 1999
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Research Field
  
  Hygiene
- Research Institution
  Yamaguchi University
Molecular mechanisms of leukocytes activation by heavy metals : Free radical generation system
- Principal Investigator
  
  OGINO Keiki
- Project Period (FY)
  1993 – 1995
- Research Category
  
  Grant-in-Aid for General Scientific Research (B)
- Research Field
  
  Public health/Health science
- Research Institution
  Kanazawa University
  Yamaguchi University
Effects trihalometane and clorinated orgnic solvents for the enviroment and ecology.Principal Investigator
- Principal Investigator
  
  HOBARA Tatuya
- Project Period (FY)
  1991 – 1993
- Research Category
  
  Grant-in-Aid for General Scientific Research (B)
- Research Field
  
  公衆衛生学
- Research Institution
  Yamaguchi University
Experimental Examination of Organic Toxicity for Trihalomethane.Principal Investigator
- Principal Investigator
  
  HOBARA Tatsuya
- Project Period (FY)
  1989 – 1990
- Research Category
  
  Grant-in-Aid for General Scientific Research (C)
- Research Field
  
  公衆衛生学
- Research Institution
  Yamaguchi University
Effects of organic solvents inhalation on left ventricular contractility
- Principal Investigator
  
  KOBAYASHI Haruo, 酒井恒美
- Project Period (FY)
  1987 – 1988
- Research Category
  
  Grant-in-Aid for General Scientific Research (C)
- Research Field
  
  公衆衛生学
- Research Institution
  Yamaguchi University

1. KOBAYASHI Haruo (00127763)

# of Collaborated Projects: 6 results

# of Collaborated Products: 0 results
2. OKUDA Masayuki (50274171)

# of Collaborated Projects: 5 results

# of Collaborated Products: 0 results
3. OGINO Keike (70204104)

# of Collaborated Projects: 3 results

# of Collaborated Products: 0 results
4. SHINODA Akira (40192108)

# of Collaborated Projects: 3 results

# of Collaborated Products: 0 results
5. KUNITSUGU Ichiro (80314798)

# of Collaborated Projects: 3 results

# of Collaborated Products: 0 results
6. KAWATA Keisuke (20284242)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
7. SUGIYAMA Shinichi (50335725)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
8. 酒井恒美 (70116721)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
9. ISHIYAMA Hironobu

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results

HOBARA Tatsuya 芳原 達也

Research Projects

Co-Researchers

Evaluation method for DNA damage and dysfunction of spermatogenic cells due to Bromopropanes

Principal Investigator

Project Period (FY)

Research Category

Research Field

Research Institution

Investigation of mechanism of central nervous system disorder due to chlorinatedPrincipal Investigator

Principal Investigator

Project Period (FY)

Research Category

Research Field

Research Institution

Effects of exogenous endocrine-disrupters on the brain regions related to sexual differentiation and aggressive behavior

Principal Investigator

Project Period (FY)

Research Category

Research Institution

血管平滑筋における毒性評価方法の展開-有機塩素系化合物の血圧低下機序解明-

Principal Investigator

Project Period (FY)

Research Category

Research Field

Research Institution

Investigation of mechanism of central nervous system disorder due to chlorinated hydrocarbons

Principal Investigator

Project Period (FY)

Research Category

Research Field

Research Institution

Evaluation of neural toxicity of organic solvents using primary culture neuronsPrincipal Investigator

Principal Investigator

Project Period (FY)

Research Category

Research Field

Research Institution

Molecular mechanisms of leukocytes activation by heavy metals : Free radical generation system

Principal Investigator

Project Period (FY)

Research Category

Research Field

Research Institution

Effects trihalometane and clorinated orgnic solvents for the enviroment and ecology.Principal Investigator

Principal Investigator

Project Period (FY)

Research Category

Research Field

Research Institution

Experimental Examination of Organic Toxicity for Trihalomethane.Principal Investigator

Principal Investigator

Project Period (FY)

Research Category

Research Field

Research Institution

Effects of organic solvents inhalation on left ventricular contractility

Principal Investigator

Project Period (FY)

Research Category

Research Field

Research Institution

HOBARA Tatsuya 芳原達也