MIYAKAWA Tokichi 宮川都吉

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HIYAKAWA Tokichi 宮川都吉

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Researcher Number	10116676
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Affiliation (based on the past Project Information) *help	2007: Hiroshima University, Graduate School of Advanced Sciences of Matter, Professor 2006: 広島大学, 大学院先端物質科学研究科, 教授 2001 – 2005: Hiroshima University, Graduate School of Advanced Sciences of Matter, Professor, 大学院・先端物質科学研究科, 教授 1998 – 2000: 広島大学, 工学部, 教授 1988 – 1996: Fac. Engineering, Hiroshima Univ., Professor, 工学部, 教授 1986 – 1988: 広島大学, 工学部, 助教授 1986: FACULTY OF ENGINEERING, HIROSHIMA UNIVERSITY, 工学部, 助教授
Review Section/Research Field	Principal Investigator 応用微生物学・応用生物化学 / 発酵・醸造 / Biological Sciences / Applied biochemistry Except Principal Investigator Science and Engineering / 応用微生物学・応用生物化学 / 発酵・醸造
Keywords	Principal Investigator カルシニューリン / 酵母 / Ca^<2+> / Saccharomyces cerevisiae / Calcineurin / 出芽酵母 / Ca^<2+>シグナル / カルシウム / 細胞周期 / 塩耐性 … More / カチオンホメオスタシス / Yeast / salt tolerance / calcineurin / cation homeostasis / カルシニューリンニューリン / MAPキナーゼ / チェックポイント / Ca^<2+>シグナル伝達 / 細胞周期制御 / S-アデノシルメチオニン / 浸透圧応答経路 / 細胞周期チェックポイント / プロテインキナーゼC / Cell cycle regulation / HOG pathway / Protein kinase C / 性フェロモン / Saccharomyces cereuisiae / FK506 / イオンホメオスタシス / cAMP / ABCトランスポーター / 多剤耐性 / Salt tolerance / veast / Ca2+シグナル伝達 / Ca^<2+> signaling / Cell cycle / 薬剤スクリーニング / 生理活性物質 / 免疫抑制剤 / Ca2+ signal / Drug screening / MAP kinase / 細胞周期抑制 / S-アデノシルホモシステイン / Ca2+ signal transduction / S-adenosyl methionine / Cell cycle checkpoint / Ca2+シグナル / ラディシコール / YAP1 / Saccharomvces cerevisiae / Ca^<2+> sienal transduction / S-adenosvl methionine / Cell cycle checknoint / 異担子菌酵母 / 性接合 / 細胞表面蛋白質 / 細胞間認識 / Basidiomycetous yeast / Sexual conjugation / Cell surface proteins / Mating pheromone / ファルネシル化 / クローニング / 遺伝子 / Mating Pheromone / Farnesylation … More Except Principal Investigator セルラーゼ / キシラナーゼ / 酵母育種 / リグノセルロ-ス / 爆砕 / リグニンペルオキシダ-ゼ / キシラン / セルラ-ゼ / キシロ-ス / Saccharomyces cerevisiae / エタノ-ル / 細胞周期 / DNA複製 / Penicillium decumbens / Ca^<2+> / セルローズ発酵酵母 / キシラン発酵酵母 / βーグルコシダーゼ / βーキシロシターゼ / 酵素の分泌 / リグノセルロース / エタノール / 水蒸気爆砕 / パーオキシダーゼ / 抽出発酵 / キシラーゼ / キシロース / 酵母 / Ca^<2+>シグナル伝達 / ポジティブスクリーニング / Tram Bau / 和羌活 / 木蝴蝶 / 生でん粉分解酵素 / β-キシロシダーゼ / 分泌シグナル / Zymomonas宿主ベクター / Zymomonasプロモーター / 耐熱性酵母 / クローン化 / キシローズ還元酵素 / Zymomonas / キシロビオーズ醗酵 / M期終了 / 信号伝達 / トリコスタチン / 低分子量Gタンパク質 / チェックポイント / 出芽酵母 / 低分子量G蛋白質 / IL-2 / 線維芽細胞 / cell cycle / end of mitosis / signal transduction / Trichustatin / small G protein / check point / 液体アルカン / ウンデカン-2-オン / 脂肪酸代謝 / 脂質の分泌生産 / アグロ・ペテロール / バイオリアクター / アルカン醗酵 / ペニシリウム・デカンベンス / 植物石油 / Liquid Alkanes / Secretive Production of Lipids / Fatty Acid Metabolism / n-Undecane-2-one / Agro-Petrol / 子のう胞子形成 / 2μmDNA / ペルオキシソーム / トランスメンブレンシグナリング / カルモジュリン依存性プロテインキナーゼ / 核膜の物質輸送 / 下等真核生物 / オルガネラ形成 / 核膜ATPase / 性分化 / トランスメンブレンシグナリング機構 / DNAの核内輸送 / Sporulation / 2 um DNA / Peroxisome / Transmembrane signaling / calmodulin depandent protein kinase / Cell division cycle / DNA replication Less

東南アジアの天然薬物から酵母Ca^<2+>シグナル伝達阻害物質の探索と医薬への応用
- Principal Investigator
  
  KADOTA Shigetoshi
- Project Period (FY)
  2005
- Research Category
  
  Grant-in-Aid for Scientific Research on Priority Areas
- Review Section
  
  Science and Engineering
- Research Institution
  University of Toyama
Basic and Applied Research on tie Roles of Ca^<2+>-Signal-mediated Cell-Cycle Regulation in Budding Yeast.Principal Investigator
- Principal Investigator
  
  MIYAKAWA Tokichi
- Project Period (FY)
  2005 – 2007
- Research Category
  
  Grant-in-Aid for Scientific Research (A)
- Research Field
  
  Applied biochemistry
- Research Institution
  Hiroshima University
Cell cycle regulation by Ca2+ and its physiological role in yeastPrincipal Investigator
- Principal Investigator
  
  MIYAKAWA Tokichi
- Project Period (FY)
  2002 – 2004
- Research Category
  
  Grant-in-Aid for Scientific Research (A)
- Research Field
  
  応用微生物学・応用生物化学
- Research Institution
  HIROSHIMA UNIVERSITY
Screening of bio-active substances by using a peculiar phenotype of yeast mutantPrincipal Investigator
- Principal Investigator
  
  MIYAKAWA Tokichi
- Project Period (FY)
  1999 – 2002
- Research Category
  
  Grant-in-Aid for Scientific Research (B)
- Research Field
  
  応用微生物学・応用生物化学
- Research Institution
  HIROSHIMA UNIVERSITY
酵母の多剤耐性における多様なABC蛋白の機能および発現制御ネットワークPrincipal Investigator
- Principal Investigator
  
  宮川都吉
- Project Period (FY)
  1998 – 2002
- Research Category
  
  Grant-in-Aid for Scientific Research on Priority Areas
- Review Section
  
  Biological Sciences
- Research Institution
  Hiroshima University
Molecular analysis of cell cycle regulation by Ca^<2+>Principal Investigator
- Principal Investigator
  
  MIYAKAWA Tokichi
- Project Period (FY)
  1998 – 2001
- Research Category
  
  Grant-in-Aid for Scientific Research (B)
- Research Field
  
  応用微生物学・応用生物化学
- Research Institution
  HIROSHIMA UNIVERSITY
酵母のイオンホメオスタシスにおけるNa^+ポンプとK^+チャンネルの機能協関Principal Investigator
- Principal Investigator
  
  宮川都吉
- Project Period (FY)
  1995
- Research Category
  
  Grant-in-Aid for Scientific Research on Priority Areas
- Research Institution
  Hiroshima University
Molecular mechanism of salt tolerance in yeastPrincipal Investigator
- Principal Investigator
  
  MIYAKAWA Tokichi
- Project Period (FY)
  1995 – 1996
- Research Category
  
  Grant-in-Aid for Scientific Research (B)
- Research Field
  
  応用微生物学・応用生物化学
- Research Institution
  HIROSHIMA UNIVERSITY
酵母のストレス応答におけるカルシニューリンの役割Principal Investigator
- Principal Investigator
  
  宮川都吉
- Project Period (FY)
  1993
- Research Category
  
  Grant-in-Aid for Scientific Research on Priority Areas
- Research Institution
  Hiroshima University
Molecular mechanisms of G1/s transition
- Principal Investigator
  
  TUH-E Akio
- Project Period (FY)
  1993 – 1995
- Research Category
  
  Grant-in-Aid for Scientific Research on Priority Areas
- Research Institution
  The University of Tokyo
Biochemical production of liquid alkanes from biomasses
- Principal Investigator
  
  FUKUI Sakuzo
- Project Period (FY)
  1993 – 1995
- Research Category
  
  Grant-in-Aid for Developmental Scientific Research (B)
- Research Field
  
  応用微生物学・応用生物化学
- Research Institution
  FUKUYAMA Univ.
リグノセルロ-ス資源の生物燃料への変換
- Principal Investigator
  
  吉田敏臣
- Project Period (FY)
  1991
- Research Category
  
  Grant-in-Aid for Scientific Research on Priority Areas
- Research Institution
  Osaka University
リグノセルロ-ス資源の生物燃料への変換
- Principal Investigator
  
  吉田敏臣
- Project Period (FY)
  1990
- Research Category
  
  Grant-in-Aid for Scientific Research on Priority Areas
- Research Institution
  Osaka University
リグノセルロース資源の生物燃料への変換
- Principal Investigator
  
  吉田敏臣
- Project Period (FY)
  1990 – 1992
- Research Category
  
  Grant-in-Aid for Scientific Research on Priority Areas
- Research Institution
  Osaka University
生物燃料直接発酵菌の育種
- Principal Investigator
  
  岡田弘輔
- Project Period (FY)
  1987 – 1989
- Research Category
  
  Grant-in-Aid for Scientific Research on Priority Areas
- Research Institution
  Osaka University
生物燃料直接醗酵菌の育種
- Principal Investigator
  
  岡田弘輔
- Project Period (FY)
  1987
- Research Category
  
  Grant-in-Aid for Scientific Research on Priority Areas
- Research Institution
  Osaka University
生物燃料直接発酵菌の育種
- Principal Investigator
  
  岡田弘輔
- Project Period (FY)
  1987 – 1988
- Research Category
  
  Grant-in-Aid for Scientific Research on Priority Areas
- Research Institution
  Osaka University
Studies on the biosynthesis and secretion of mating pheromone (farnesyl peptide) in a heterobasidiomycetous yeast.Principal Investigator
- Principal Investigator
  
  MIYAKAWA Tokichi
- Project Period (FY)
  1987 – 1989
- Research Category
  
  Grant-in-Aid for General Scientific Research (B)
- Research Field
  
  発酵・醸造
- Research Institution
  HIROSHIMA UNIVERSITY
Controls of gene expression in lower eukaryotes
- Principal Investigator
  
  TSUCHIYA Eiko, 福井作蔵
- Project Period (FY)
  1986 – 1988
- Research Category
  
  Grant-in-Aid for General Scientific Research (A)
- Research Field
  
  発酵・醸造
- Research Institution
  HIROSHIMA UNIVERSITY
METABOLISM OF CELL SURFACE PROTEINS AND ITS ROLE FOR SEXUAL CONJUGATION IN HETEROBASIDIOMYCETOUS YEASTPrincipal Investigator
- Principal Investigator
  
  MIYAKAWA TOKICHI
- Project Period (FY)
  1985 – 1986
- Research Category
  
  Grant-in-Aid for General Scientific Research (C)
- Research Field
  
  発酵・醸造
- Research Institution
  HIROSHIMA UNIVERSITY

All 2008 2007 2006 2005 2004

All Journal Article Book Patent

[Book] 蛋白質核酸酵素酵母による低分子阻害物質標的蛋白質の同定2007
- Author(s)
  宮川都吉
- Total Pages
  5
- Publisher
  共立出版
- Description
  「研究成果報告書概要(和文)」より
- Data Source
  KAKENHI-PROJECT-17208009
[Book] 酵母のすべてストレス応答性MAPキナーゼ経路とCa^<2÷>シグナル伝達2007
- Author(s)
  宮川都吉
- Total Pages
  7
- Publisher
  シュプリンガー・ジャパン
- Description
  「研究成果報告書概要(和文)」より
- Data Source
  KAKENHI-PROJECT-17208009
[Book] 酵母のすべてストレス応答性MAPキナーゼ経路とCa^<2+>シグナル伝達2007
- Author(s)
  宮川都吉
- Total Pages
  7
- Publisher
  シュプリンガー・ジャパン
- Data Source
  KAKENHI-PROJECT-17208009
[Book] ABC蛋白質2005
- Author(s)
  宮川都吉, Andreea C. Tutulan-Cunita
- Total Pages
  13
- Publisher
  学会出版センター
- Data Source
  KAKENHI-PROJECT-17208009
[Book] 真核生物の多剤耐性ABCトランスポーターの構造と機能2005
- Author(s)
  宮川都吉, A.C.Tutulan-Cunita
- Publisher
  学会出版センター(印刷中)
- Data Source
  KAKENHI-PROJECT-14206012
[Book] 真核生物の多剤耐性ABCトランスポーターの構造と機能2005
- Author(s)
  宮川都吉
- Publisher
  学会出版センター(印刷中)
- Description
  「研究成果報告書概要(和文)」より
- Data Source
  KAKENHI-PROJECT-14206012
[Journal Article] Inhibition of Ca^<2+>-signal-sependent growth regulation by eadicicol in budding yeast2008
- Author(s)
  R., Chanklan, E., Aihara, S., Koga, H., Takahashi, M., Mizunuma, T., Miyakawa
- Journal Title
  
  Biosci, Biotechnol. Biochem 72
  
  Pages: 132-138
- Description
  「研究成果報告書概要(欧文)」より
- Data Source
  KAKENHI-PROJECT-17208009
[Journal Article] Identification of Tupl and Cyc8 mutations defective in the responses to osmotic stress2008
- Author(s)
  Y., Kobayashi, T., Thai, M., Mizunuma, I., Okada, A., Shitamukai, D., Hirata, T., Miyakawa
- Journal Title
  
  Biochem. Biophys. Res. Commun 368
  
  Pages: 50-55
- Description
  「研究成果報告書概要(欧文)」より
- Data Source
  KAKENHI-PROJECT-17208009
[Journal Article] Identification of Tubl a-Tubulin as a Potential Target for NKH-7, a cytotoxic 1-Naphthol Derivative Compound2008
- Author(s)
  R., Chanklan, M., Mizunuma, N., Kongkathip, K., Hasitapan, B., Kongkathip, T., Miyakawa
- Journal Title
  
  Biosel Biotechnol Biochem 72(in Press)
- Description
  「研究成果報告書概要(欧文)」より
- Data Source
  KAKENHI-PROJECT-17208009
[Journal Article] YCM1008A, a novel Ca^<2+>-signaling inhibitor, produced by Fusarium sp.YCM10082007
- Author(s)
  F., Koizumi, N., Fukumitsu, J., Zhao, R., Chanklan, T., Miyakawa, S., Kawahara, S., Iwamoto, M., Suzuki, S., Kakita, E.S., Rahayu, S., Hosokawa, K., Tatsuta, M., Ichimura
- Journal Title
  
  J Antibiotics 60
  
  Pages: 455-458
- Description
  「研究成果報告書概要(欧文)」より
- Data Source
  KAKENHI-PROJECT-17208009
[Journal Article] Physiological roles of calcineurin in Saccharomyces cerevisiae with special emphasis on its roles in G_2/M cell-cycle regulation2007
- Author(s)
  Tokichi Miyakawa
- Journal Title
  
  Biosci. Biotechnol. Biochem. 71(印刷中)
- Data Source
  KAKENHI-PROJECT-17208009
[Journal Article] Physiological Roles of Calcineurin in Saccharomyces cerevisiae with Special Emphasis on Its Roles in G2/M Cell-Cycle Regulation2007
- Author(s)
  T. Miyakawa
- Journal Title
  
  Biosci Biotechnol Biochem. 71・3
  
  Pages: 633-645
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-17208009
[Journal Article] Physiological roles of calcineurin in Saccharomyces cerevisiae with special emphasis on its roles in G2/M call-cycle regulation2007
- Author(s)
  T., Miyakawa, M., Mizunuma
- Journal Title
  
  Biosci Biotechnol Biocbem 71
  
  Pages: 633-645
- Description
  「研究成果報告書概要(欧文)」より
- Data Source
  KAKENHI-PROJECT-17208009
[Journal Article] Physiological roles of calcineurin in Saccharomyces cerevisiae with special emphasis on its roles in G_2/M cell- cycle regulation.2007
- Author(s)
  T, Miyakawa
- Journal Title
  
  Biosci. Biotechnol. Biochem. 71
  
  Pages: 633-645
- Description
  「研究成果報告書概要(和文)」より
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-17208009
[Journal Article] Involvement of Yaplp downregulation in calcineurin-mediated G2 cell-cycle regulation in Saccharomyces cerevisiae2006
- Author(s)
  H., Yokoyama, M., Mizunuma, M., Okamoto, D., Hirata, T., Miyakawa
- Journal Title
  
  EMBO reports 7
  
  Pages: 519-524
- Description
  「研究成果報告書概要(欧文)」より
- Data Source
  KAKENHI-PROJECT-17208009
[Journal Article] Ca^<2+>シグナルによる酵母細胞周期制御機構解明と医薬シーズ探索への応用2006
- Author(s)
  宮川都吉
- Journal Title
  
  バイオサイエンスとバイオインダストリー 64・7
  
  Pages: 373-378
- Data Source
  KAKENHI-PROJECT-17208009
[Journal Article] Ca^<2+>シグナルによる酵母の細胞周期制御機構解明と医薬シーズ探索への応用2006
- Author(s)
  宮川都吉、
- Journal Title
  
  バイオサイエンスとバイオインダストリー 64
  
  Pages: 373-378
- NAID
  10017621157
- Description
  「研究成果報告書概要(和文)」より
- Data Source
  KAKENHI-PROJECT-17208009
[Journal Article] Identification of Saccharomyces cerevisiae Ribosomal Protein L3 as a Target of Curvularol, a G_1-Specific Inhibitor of Mammalian Cells2006
- Author(s)
  Y., Kobayashi, M., Mizunuma, H., Osada, T., Miyakawa
- Journal Title
  
  Biosci, Biotechnol. Biochem 70
  
  Pages: 2451-2459
- Description
  「研究成果報告書概要(欧文)」より
- Data Source
  KAKENHI-PROJECT-17208009
[Journal Article] Role of L-histidine in conferring tolerance to Ni^<2+> in Saccharomyces cerevisiae2005
- Author(s)
  L.C., Farcasanu, M., Mizunuma, F., Nishiyama, T., Miyakawa
- Journal Title
  
  Biosci. Biotechnol. Biochem 69
  
  Pages: 2343-2348
- Description
  「研究成果報告書概要(欧文)」より
- Data Source
  KAKENHI-PROJECT-17208009
[Journal Article] Implication of Pkelp protein Kinase C in sustaining Cln2p level and polarized bud growth in response to calcium signaling in Saccharonryces cerevisiae2005
- Author(s)
  M., Mizunuma, D., Hirata, T., Miyakawa
- Journal Title
  
  J. Cell Scl 118
  
  Pages: 4219-4229
- Description
  「研究成果報告書概要(欧文)」より
- Data Source
  KAKENHI-PROJECT-17208009
[Journal Article] Involvement of Saccharomyces cerevisiae Pdr5p ATP-binding cassette Transporter in calcium homeostasis2005
- Author(s)
  A.C., Tutulan-Cunita, T., Ohnishi, M., Mizunuma, D., Hirata, T., Miyakawa
- Journal Title
  
  Biosci. Biotechnol. Biochem 69
  
  Pages: 857-860
- Description
  「研究成果報告書概要(欧文)」より
- Data Source
  KAKENHI-PROJECT-17208009
[Journal Article] Structure and function of eukaryotic ABC transporter2005
- Author(s)
  Tokichi Miyakawa
- Journal Title
  
  Gakkai Shuppan Center (in press)
- Description
  「研究成果報告書概要(欧文)」より
- Data Source
  KAKENHI-PROJECT-14206012
[Journal Article] Mutational analysis of the yeast multidrug resistance ABC transporter Pdr5p with altered drug specificity2005
- Author(s)
  A.C., Tutulan-Cunita, M.o., Mikoshi, M., Mizunurna, D., Himta, T., Miyakawa
- Journal Title
  
  Gene Cells 10
  
  Pages: 409-420
- Description
  「研究成果報告書概要(欧文)」より
- Data Source
  KAKENHI-PROJECT-17208009
[Patent] 微小管重合阻害化合物、およびその利用2008
- Inventor(s)
  宮川都吉, 他
- Industrial Property Rights Holder
  広島大学, カセサート大
- Industrial Property Number
  2008-026621
- Filing Date
  2008-02-06
- Description
  「研究成果報告書概要(和文)」より
- Data Source
  KAKENHI-PROJECT-17208009
[Patent] 2H-ピラノ[3, 2-c]ピリジン-5(6H)-オン誘導体2007
- Inventor(s)
  宮川都吉, 他
- Industrial Property Rights Holder
  広島大学, 他
- Industrial Property Number
  2007-048434
- Filing Date
  2007-02-28
- Description
  「研究成果報告書概要(和文)」より
- Data Source
  KAKENHI-PROJECT-17208009
[Patent] 酵母変異体の利用2004
- Inventor(s)
  宮川都吉, 水沼正樹, 平田大
- Industrial Property Rights Holder
  牟田泰三
- Filing Date
  2004-03-22
- Data Source
  KAKENHI-PROJECT-14206012

1. HIRATA Dai (30243603)

# of Collaborated Projects: 6 results

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2. 吉田敏臣 (00029290)

# of Collaborated Projects: 6 results

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3. 堀之内末治 (80143410)

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4. FUKUI Sakuzo (60013299)

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5. 岡田弘輔 (20028947)

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6. 外村健三 (90124867)

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7. 鵜高重三 (70023463)

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8. 別府輝彦 (80011873)

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9. 桑原正章 (40035978)

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10. 沢田達郎 (80019728)

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11. TUH-E Akio (90029249)

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12. KADOTA Shigetoshi (90115163)

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13. TSUCHIYA Eiko (90127671)

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14. 卜部格 (60029246)

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15. MINAMI Yasuhiro (70229772)

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16. YOSHIDA Minoru (80191617)

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17. TANAKA Kazuma (60188290)

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18. ARAKI Hiroyuki (20151160)

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19. MATSUZAKI Hiroaki (90222299)

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20. HATANO Takushi (60198752)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
21. MIZUTA Keiko (40166012)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
22. MIZUNUMA Masaki (10343295)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
23. KAMIRYO Tatsuyuki (50025649)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
24. 小林猛 (10043324)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
25. 手塚康弘 (70236975)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
26. 秋山徹 (70150745)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
27. TAKAHASHI Hidetoshi

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results

MIYAKAWA Tokichi 宮川 都吉

HIYAKAWA Tokichi 宮川 都吉

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Basic and Applied Research on tie Roles of Ca^<2+>-Signal-mediated Cell-Cycle Regulation in Budding Yeast.Principal Investigator

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Cell cycle regulation by Ca2+ and its physiological role in yeastPrincipal Investigator

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Screening of bio-active substances by using a peculiar phenotype of yeast mutantPrincipal Investigator

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酵母の多剤耐性における多様なABC蛋白の機能および発現制御ネットワークPrincipal Investigator

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Molecular analysis of cell cycle regulation by Ca^<2+>Principal Investigator

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酵母のイオンホメオスタシスにおけるNa^+ポンプとK^+チャンネルの機能協関Principal Investigator

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Molecular mechanism of salt tolerance in yeastPrincipal Investigator

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酵母のストレス応答におけるカルシニューリンの役割Principal Investigator

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MIYAKAWA Tokichi 宮川都吉

HIYAKAWA Tokichi 宮川都吉

[Book] 蛋白質核酸酵素酵母による低分子阻害物質標的蛋白質の同定2007

[Book] 酵母のすべてストレス応答性MAPキナーゼ経路とCa^<2+>シグナル伝達2007