HIRAOKI Toshifumi 平沖敏文

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平沖敏文ヒラオキトシフミ

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Researcher Number	10125346
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Affiliation (based on the past Project Information) *help	2015 – 2016: 北海道大学, 工学(系)研究科(研究院), 准教授 2014: 北海道大学, 工学(系)研究科(研究院), その他 2013: 北海道大学, 大学院歯学研究科, 特任教授 2013: 北海道大学, 工学(系)研究科(研究院), 特任教授 2012: 北海道大学, 工学(系)研究科(研究院), 教授 … More 2011: 北海道大学, 工学(系)研究科(研究院), 准教授 2003 – 2004: 北海道大学, 大学院・工学研究科, 助教授 2002: 北海道大学, 工学研究科, 助教授 2001: Hokkaido Univ. Grad. School of Eng., Asso. Prof., 大学院・工業研究科, 助教授 1999 – 2001: Hokkaido Univ., Grad. School of Eng., Ass. Pro., 大学院・工学研究科, 助教授 1999: 北海道大学, 工学研究科, 助教授 1998: 北海道大学, 大学院工学研究科, 助教授 1991 – 1993: 北海道大学, 工学部, 助教授 1988: 北海道大学, 工学部, 助教授 Less
Review Section/Research Field	Principal Investigator 高分子構造・物性(含繊維) Except Principal Investigator Surgical dentistry / Surgical dentistry / 高分子構造・物性(含繊維)
Keywords	Principal Investigator photo-isomerization / the side-chain conformation / p-phenylazobenzene / right-handed α-hellx / poly (β-n-propy L-aspartate) / helix-sense inversion / ヘリックスセンス / 高次構造制御 / 光異性化 / アゾベンゼン基 / 核磁気共鳴 / へリックスセンス / ポリペプチド … More Except Principal Investigator … More Na, K-ATPase / NMR / ESR / 全身麻酔薬 / リポソーム / Na,K-ATPase / カルシウム結合蛋白質 / カルシウムイオン / スピンラベル剤 / 電子スピン共鳴 / アルカリ性ホスファターゼ / 局所麻酔薬 / 蛋白質工学 / カルモデュリン / membrane protein / general anesthetics / spin label reagent / rotational correlation time / order parameter / electron spin resonance / liposome / 蛍光 / 脂質 / タンパク質 / SDS / メタノール / オーダーパラメーター / 16-DSA / 5-DSA / 膜タンパク質 / 回転相関時間 / オーダーパラメータ / droperidol / benzodiazepin / ketamine / halothane / sevofluraae / isoflurane / alkaline phosphatase / イソフルラン / 表面構造 / サブユニット間の相互作用 / アイソザイム / ゲルろ過クロマトグラフィー / sodium dodecyl sulfate / 揮発性麻酔薬 / フルマゼニル / ベンゾジアゼピン / 吸入麻酔薬 / ベンゾジアゼピン系薬物 / リチウム塩 / ドロペリドール / NMRスペクトル / イソフルレン / Metal ions / Dynamics / Polypeptides / Polysaccharides / Sol-gel transition / Physical gel / 分子運動 / ^<13>C NMR / マンガンイオンのESR / DSC / 金属イオンとの相互作用 / ジェランガム / 多糖水溶液 / ゾルーゲル転移 / 金属イオン / ダイナミクス / ポリペプチド / 多糖 / ゾル-ゲル転移 / 物理ゲル / BCNMR / IHNMR / 常磁性緩和 / Cuイオン / 動的挙動 / 構造 / コポリマー / ポリアミノ酸 / 化学交換 / スピンラベル / 生体モデル膜 / 核磁気共鳴 / 麻酔薬の作用機序 / 骨芽細胞 / リン脂質 / ラット脳 / Mg-ATPase / Ca-ATPase / 有害作用 / 麻酔作用 / カルモデユリン Less

The study of the site of action of volatile general anesthetics using ESR and NMR
- Principal Investigator
  
  SHIBUYA MAKIKO
- Project Period (FY)
  2012 – 2016
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Research Field
  
  Surgical dentistry
- Research Institution
  Hokkaido University
Study of pharmacological action and the adverse effect of the local anesthetic from a new viewpoint
- Principal Investigator
  
  FUKUSHIMA KAZUAKI
- Project Period (FY)
  2011 – 2013
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Research Field
  
  Surgical dentistry
- Research Institution
  Hokkaido University
The reaction mechanism of general anesthetics studied by electron spin resonance and fluorescence measurement technique
- Principal Investigator
  
  SUZUKI Kuniaki
- Project Period (FY)
  2002 – 2004
- Research Category
  
  Grant-in-Aid for Scientific Research (B)
- Research Field
  
  Surgical dentistry
- Research Institution
  HOKKAIDO UNIVERSITY
Structure and Dynamics in Physical Gels of Biopolymers
- Principal Investigator
  
  TSUTSUMI Akihiro
- Project Period (FY)
  1999 – 2000
- Research Category
  
  Grant-in-Aid for Scientific Research (B).
- Research Field
  
  高分子構造・物性(含繊維)
- Research Institution
  HOKKAIDO UNIVERSITY
Approach to reaction mechanism of general anesthetics by biological and physicochemical methods from new viewpoint
- Principal Investigator
  
  SUZUKI Kuniaki
- Project Period (FY)
  1999 – 2001
- Research Category
  
  Grant-in-Aid for Scientific Research (B)
- Research Field
  
  Surgical dentistry
- Research Institution
  HOKKAIDO UNIVERSITY
POLYPEPTIDE STRUCTURE AND DYNAMICS CONTROLLED BY PHOT0-ISOMERIZATIONPrincipal Investigator
- Principal Investigator
  
  HIRAOKI Toshifumi
- Project Period (FY)
  1998 – 1999
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Research Field
  
  高分子構造・物性(含繊維)
- Research Institution
  HOKKAIDO UNIVERSITY
カルシウム結合蛋白質の金属配位構造の安定性とその動的構造変化
- Principal Investigator
  
  矢沢道生
- Project Period (FY)
  1993
- Research Category
  
  Grant-in-Aid for Scientific Research on Priority Areas
- Research Institution
  Hokkaido University
カルシウム結合蛋白質の金属配位構造の安定性とその動的構造変化
- Principal Investigator
  
  矢沢道生
- Project Period (FY)
  1992
- Research Category
  
  Grant-in-Aid for Scientific Research on Priority Areas
- Research Institution
  Hokkaido University
カルシウム結合蛋白質の金属配位構造の安定性とその動的構造方化ー遺伝子操作法によるカルモデュリンの酵素活性化機構の研究
- Principal Investigator
  
  矢沢道生
- Project Period (FY)
  1991
- Research Category
  
  Grant-in-Aid for Scientific Research on Priority Areas
- Research Institution
  Hokkaido University
常磁性金属イオンをプローブとする高分子金属錯体の構造とゆらぎの研究
- Principal Investigator
  
  引地邦男
- Project Period (FY)
  1988
- Research Category
  
  Grant-in-Aid for Scientific Research on Priority Areas
- Research Institution
  Hokkaido University

All 2012 2011

All Journal Article Presentation

[Journal Article] The effects of general anesthetics on ESR spectra of spin labels in phosphatidylcholine vesicles containing purified Na,K-ATPase or microsomal protein2012
- Author(s)
  M. Shibuya, T. Hiraoki, K. Kimura, K. Suzuki, K. Fukushima
- Journal Title
  
  Applied Surface Science
  
  Volume: 262 Pages: 102-106
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-23592977
[Journal Article] The effects of general anesthetics on ESR spectra of spin labels in phosphatidylcholine vesicles containing purified Na,K-ATPase or microsomal protein.2012
- Author(s)
  M. Shibuya, T. Hiraoki, K. Kimura, K. Suzuki, K. Fukushima
- Journal Title
  
  Applied Surface Science
  
  Volume: in press
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-23592977
[Presentation] The effects of general anesthetics on ESR spectra of spin labels in liposome containing with membrane proteins2012
- Author(s)
  M. Shibuya, K. Suzuki, K. Kimura, T. Hiraoki, K. Fukushima
- Organizer
  13th International Dental Congress on Anesthesia, Sedationand Pain Control (IFDAS 2012)
- Place of Presentation
  Kohala Coast, Big Island of Hawaii, USA
- Year and Date
  2012-03-02
- Data Source
  KAKENHI-PROJECT-23592977
[Presentation] The effects of general anesthetics on ESR spectra of spin labels in phosphatidylcholine vesicles2011
- Author(s)
  M. Shibuya, T. Hiraoki, K. Kimura, K. Fukushima, K. Suzuki
- Organizer
  3^<rd> International Symposium on Surface and Interface of Biomedicine
- Place of Presentation
  Hokkaido University (Sapporo)
- Year and Date
  2011-07-11
- Data Source
  KAKENHI-PROJECT-23592977
[Presentation] The effects of general anesthetics on ESR spectra of spin labels in phosphatidylcholine vesicles.2011
- Author(s)
  M. Shibuya, T. Hiraoki, K. Kimura, K. Fukushima, K. Suzuki
- Organizer
  3rd International Symposium on Surface and Interface of Biomedicine
- Place of Presentation
  北海道大学（札幌市）
- Data Source
  KAKENHI-PROJECT-23592977

1. SUZUKI Kuniaki (40133748)

# of Collaborated Projects: 4 results

# of Collaborated Products: 5 results
2. 矢沢道生 (50101134)

# of Collaborated Projects: 3 results

# of Collaborated Products: 0 results
3. FUKUSHIMA KAZUAKI (00002361)

# of Collaborated Projects: 2 results

# of Collaborated Products: 5 results
4. FUJISAWA Toshiaki (30190028)

# of Collaborated Projects: 2 results

# of Collaborated Products: 0 results
5. SHIBUYA Makiko (30399951)

# of Collaborated Projects: 2 results

# of Collaborated Products: 5 results
6. KIMURA Yukifumi (00292037)

# of Collaborated Projects: 2 results

# of Collaborated Products: 5 results
7. TSUTSUMI Akihiro (80000884)

# of Collaborated Projects: 2 results

# of Collaborated Products: 0 results
8. DEYAMA Yoshiaki (80271667)

# of Collaborated Projects: 2 results

# of Collaborated Products: 0 results
9. YOSHIMURA Yoshitaka (30230816)

# of Collaborated Projects: 2 results

# of Collaborated Products: 0 results
10. IIDA Akira (90292036)

# of Collaborated Projects: 2 results

# of Collaborated Products: 0 results
11. ISHII Fumiaki (30001308)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
12. 長谷由理 (20626121)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
13. 引地邦男 (30000805)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
14. 鴇田昌之 (80163963)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
15. 戸倉清一 (40000806)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
16. HONMA Shouichi

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
17. 津田栄

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results

HIRAOKI Toshifumi 平沖 敏文

平沖 敏文 ヒラオキ トシフミ

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POLYPEPTIDE STRUCTURE AND DYNAMICS CONTROLLED BY PHOT0-ISOMERIZATIONPrincipal Investigator

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[Journal Article] The effects of general anesthetics on ESR spectra of spin labels in phosphatidylcholine vesicles containing purified Na,K-ATPase or microsomal protein2012

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[Journal Article] The effects of general anesthetics on ESR spectra of spin labels in phosphatidylcholine vesicles containing purified Na,K-ATPase or microsomal protein.2012

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[Presentation] The effects of general anesthetics on ESR spectra of spin labels in liposome containing with membrane proteins2012

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[Presentation] The effects of general anesthetics on ESR spectra of spin labels in phosphatidylcholine vesicles2011

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[Presentation] The effects of general anesthetics on ESR spectra of spin labels in phosphatidylcholine vesicles.2011

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HIRAOKI Toshifumi 平沖敏文

平沖敏文ヒラオキトシフミ