ISHIKAWA Fumio 石川文雄

Researcher Number	10130345
Affiliation (based on the past Project Information) *help	2016 – 2018: 東邦大学, 医学部, 講師 2012 – 2014: 東邦大学, 医学部, 講師 2007 – 2009: Toho University, 医学部, 講師 1999 – 2002: 東邦大学, 医学部, 講師 1992: Toho University School of Medicine Lecture, 医学部, 講師 1991: 東邦大学, 医学部, 講部 1990: 東邦大学, 医学部, 助手
Review Section/Research Field	Principal Investigator Radiation science Except Principal Investigator Otorhinolaryngology / Laboratory medicine / Orthopaedic surgery / Digestive surgery / Immunology
Keywords	Principal Investigator CD80抗原 / 細胞内シグナル伝達系 / NF-kB / エタノール / superinduction / シグナル伝達経路 / Lynチロシンキナーゼ / A20-HL細胞 / NF-kB転写因子 / サイクロヘキシミド … More / 抗原提示 / super-induction / プロテオーム解析 / CD80 / 放射線 … More Except Principal Investigator OPLL / 自己免疫 / モデルマウス / アレルギー、喘息 / 好酸球性副鼻腔炎 / IgG4-CRS / IgG4 / ミクリッツ病 / 細胞間隙 / 副鼻腔粘膜 / デスモグレイン3 / 自己抗原 / 自己抗体 / デスモグレイン３ / ＩｇＧ４ / 慢性副鼻腔炎 / 難治性慢性炎症 / Competitive ELISA / Affinity content / RAD / RT-PCR / Interleukin-2 / DLST / Anti-drug antibody / Drug allergy / サイトカイン / PCR法 / competitive ELISA / 抗薬剤抗体 / 感作T細胞 / インターロイキン2 / インタ-ロイキン-2 / cELISA法 / 親和性定数 / RAD法 / RT-PCR法 / インターロイキン-2 / 薬剤芽球化試験 / 薬剤抗体 / 薬剤アレルギー / CD4 positive T cell / T cell function / Mononucleocyte / Cytokine / Cell growth factor / Cultured cell / antigen responce / Ankylosing spondylitis / シグナル伝達 / 免疫能低下 / 骨化 / B細胞機能低下 / 抗原提示能 / シグナル伝達物質 / 増殖因子 / T細胞機能低下 / 強直性脊椎炎 / tumor marker / autocrin growth / granulocyte macrophage-colony stimulating factor / tumor necrosis factor-alpha / interleukin-6 / interleukin-2 / interleukin-1 / patients with cancer / auto crine増殖 / ILー1 / サイトカイン療法 / autocrine増殖 / ILー6 / ILー2 / GMーCSF / TNFーα / 侵潤リンパ球 / 肝癌 / 腫瘍マーカー / オートクリン増殖 / IL-2 / IL-6 / IL-1 / GM-CSF / TNF-α / 担癌患者 / ネガティブセレクション / Ｔ細胞 / 免疫寛容 / 自己免疫疾患 Less

Clarification of etiology elucidation of eosinophilic chronic sibusitis and making of the model mouse
- Principal Investigator
  
  OTA Yasushi
- Project Period (FY)
  2016 – 2018
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Research Field
  
  Otorhinolaryngology
- Research Institution
  Toho University
Suppression mechanisms of autoimmune diseases by SATB1
- Principal Investigator
  
  KONDO Motonari
- Project Period (FY)
  2012 – 2014
- Research Category
  
  Grant-in-Aid for Scientific Research (B)
- Research Field
  
  Immunology
- Research Institution
  Toho University
Analysis of the CD80 up-regulation by low-dose ionizing radiation.Principal Investigator
- Principal Investigator
  
  ISHIKAWA Fumio
- Project Period (FY)
  2007 – 2009
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Research Field
  
  Radiation science
- Research Institution
  Toho University
Immunological study and etiotropic development in monogenesis of Ankylosing spondylitis
- Principal Investigator
  
  OKADA Yayoi
- Project Period (FY)
  1999 – 2002
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Research Field
  
  Orthopaedic surgery
- Research Institution
  Department of Immunology, Toho University School of Medicine
Development of the high sensitivity measurements for drug-allergy
- Principal Investigator
  
  ITO Masatoshi
- Project Period (FY)
  1999 – 2001
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Research Field
  
  Laboratory medicine
- Research Institution
  Toho university
Serum cytokine levels and immunological function in patients with cancer
- Principal Investigator
  
  KURAMOTO Shintarou
- Project Period (FY)
  1990 – 1992
- Research Category
  
  Grant-in-Aid for General Scientific Research (B)
- Research Field
  
  Digestive surgery
- Research Institution
  Toho University School of Medicine

All 2017 2013 2009 2008 2007

All Journal Article Presentation

[Journal Article] A case of refractory chronic rhinosinusitis with anti-desmoglein 3 IgG4 autoantibody2017
- Author(s)
  Yasushi Ota, Fumio Ishikawa, Toshiya Sato, Nobuyuki Hiruta,
- Journal Title
  
  Allegology International
  
  Volume: in press
- NAID
  130006179452
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-16K11218
[Journal Article] CCR7 ligands are required for development of experimental autoimmune encephalomyelitis through generating IL-23-dependent Th17 cells.2009
- Author(s)
  Kuwabara T, Ishikawa F, Yasuda T, Aritomi K, Nakano H, Tanaka Y, Okada Y, Lipp M, Kakiuchi T.
- Journal Title
  
  J Immunol 183
  
  Pages: 2513-21
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-19591466
[Journal Article] CCR7 ligands are required for development of experimental autoimmune encephalomyelitis through generating IL-23-dependent Th17 cells2009
- Author(s)
  Kuwabara T, Ishikawa F, Yasuda T, Aritomi K, Nakano H, Tanaka Y, Okada Y, Lipp M, Kakiuchi T.
- Journal Title
  
  J.Immunol. 183
  
  Pages: 2513-2521
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-19591466
[Journal Article] Inhaled etanol increases antigen-specific IgE production via enhanced Th2 lineage differntiation2008
- Author(s)
  Junko Nakazato, Fumio Ishikawa, Taku Kuwabara, Terutaka Kakiuchi
- Journal Title
  
  J Med Soc Toho 55
  
  Pages: 10-22
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-19591466
[Journal Article] Inhaled etanol increases antigen-specific IgE production via enhanced Th2 lineage differntiation.2008
- Author(s)
  Junko Nakazato, Fumio Ishikawa, Taku Kuwabara, Terutaka Kakiuchi
- Journal Title
  
  J Med Soc Toho 55(2
  
  Pages: 10-22
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-19591466
[Journal Article] Effect of Fluoroquinolones on body temperature of mice.2008
- Author(s)
  Shuichi Miyazaki, Fumio Ishikawa, Saburo Matsuo, Keizo Yamaguch.
- Journal Title
  
  J. Antimicrob. Chemother 62
  
  Pages: 1319-1322
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-19591466
[Journal Article] Inhaled etanol increases antigen-specific IgE production viaenhanced Th2 lineage differntiation2008
- Author(s)
  Junko Nakazato, Fumio Ishikawa, Taku Kuwabara, Terutaka Kakiuchi
- Journal Title
  
  J Med Soc Toho 55
  
  Pages: 10-22
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-19591466
[Journal Article] Isolation and characterization of the N-linked oligosaccharides in nacrein from Pinctada fucata.2008
- Author(s)
  Daisuke Takakura, Michiko Norizuki, Fumio Ishikawa, Tetsuro Sama
- Journal Title
  
  Mar Biotechnol 10
  
  Pages: 290-6
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-19591466
[Journal Article] Effect of Fluoroquinolones on body temperature of mice.2008
- Author(s)
  Shuichi Miyazaki, Fumio Ishikawa, Saburo Matsuo, Keizo Yamaguchi
- Journal Title
  
  J. Antimicrob. Chemother. 62
  
  Pages: 1319-1322
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-19591466
[Journal Article] Gr-1 high polumorphonuclear leukocytes and NK cells act via IL-15 to clear intracellular haemophilus influenzae in experimental murine peri-tonities and pneumonia2007
- Author(s)
  Miyazaki S, Ishikawa F, Shimizu K, Ubagai T, Edelstein PH, and Yamaguchi k.
- Journal Title
  
  J. Immunology 179
  
  Pages: 5407-5414
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-19591466
[Journal Article] A double three-step theory of brain metastasis in mice: the role of the pia mater and matrix metalloproteinases Neuropathology and Applied Neurobiology2007
- Author(s)
  N. Saito, T. Hatori, N. Murata, Z.-A. Zhang, F. Ishikawa, H. Nonaka, S. Iwabuchi, H. Samejima
- Journal Title
  
  33(3)
  
  Pages: 288-298
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-19591466
[Journal Article] Gr-1 high polumorphonuclear leukocytes and NK cells act via IL-15 to clear intracellular haemophilus influenzae in experimental murine peritonities and pneumonia.2007
- Author(s)
  Miyazaki S, Ishikawa F, Shimizu K, Ubagai T, Edelstein PH, Yamaguchi K
- Journal Title
  
  J. Immunol 179
  
  Pages: 5407-14
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-19591466
[Presentation] デスモグレイン3に対する自己抗体ＩｇＧ４が認められた難治性慢性鼻副鼻腔炎症例2017
- Author(s)
  太田　康、石川文雄、鈴木光也
- Organizer
  第56回日本鼻科学会
- Data Source
  KAKENHI-PROJECT-16K11218
[Presentation] The role of SATB1 in mouse model of autoimmune disease.2013
- Author(s)
  Mukozu T., Guo X., Tanaka Y., Ishikawa F., Kuwabara T., Kondo M.
- Organizer
  第42回　日本免疫学会総会学術集会
- Place of Presentation
  千葉県　千葉市　幕張メッセ
- Data Source
  KAKENHI-PROJECT-24390121
[Presentation] Acute ethanol inhalation down-regulates IL12 production by dendritic cells and enhances Th2 polarization2009
- Author(s)
  Fumio Ishikawa, Taku Kuwabara, Yuriko Tanaka, Naomi Yamashita, Terutaka Kakiuch
- Organizer
  第39回日本免疫学会
- Place of Presentation
  大阪
- Year and Date
  2009-12-04
- Data Source
  KAKENHI-PROJECT-19591466
[Presentation] CCR7 ligands up-regulate IL-23 through P13-kinase and NF-kB pathway in dendritic cells2009
- Author(s)
  桑原卓, 石川文雄, 田中ゆり子, 垣内史堂
- Organizer
  第39回日本免疫学会
- Place of Presentation
  大阪
- Year and Date
  2009-12-02
- Data Source
  KAKENHI-PROJECT-19591466
[Presentation] CCR7 ligands up-regulate IL-23 through PI3-kinase and NF-kB pathway in dendritic cells2009
- Author(s)
  Kuwabara T, Ishikawa F, Tanaka Y, Kakiuchi T.
- Organizer
  第39回日本免疫学会
- Place of Presentation
  大阪
- Year and Date
  2009-12-02
- Data Source
  KAKENHI-PROJECT-19591466
[Presentation] Acute ethanol inhalation down-regulates IL12 production by dendritic cells and enhances Th2 polarization.2009
- Author(s)
  Fumio Ishikawa, Taku Kuwabara, Yuriko Tanaka, Naomi Yamashita, Terutaka Kakiuch
- Organizer
  第39回日本免疫学会
- Place of Presentation
  大阪
- Year and Date
  2009-12-04
- Data Source
  KAKENHI-PROJECT-19591466
[Presentation] エタノール処理マウスの樹状細胞はTh2応答を増強する2009
- Author(s)
  石川文雄, 桑原卓, 田中ゆり子, 今井常彦, 百瀬弥寿徳, 垣内史堂
- Organizer
  第44回日本アルコール・薬物医学会
- Place of Presentation
  横浜
- Year and Date
  2009-09-08
- Data Source
  KAKENHI-PROJECT-19591466
[Presentation] エタノールは樹状細胞由来からのIL-12産生能を低下させTh2応答を増強する2009
- Author(s)
  石川文雄, 桑原卓, 田中ゆり子, 百瀬弥寿徳, 垣内史堂
- Organizer
  第20回日本生体防御学会
- Place of Presentation
  東京
- Year and Date
  2009-07-26
- Data Source
  KAKENHI-PROJECT-19591466
[Presentation] Soluble protein antigen alone efficiently elicits T cell response in mutant mice lacking expression of CCL19 and CCL221 (plt mice).2009
- Author(s)
  Tanak Y, Kuwabara T, Ishikawa F, Kakiuchi T.
- Organizer
  第39回日本免疫学会
- Place of Presentation
  大阪
- Year and Date
  2009-12-02
- Data Source
  KAKENHI-PROJECT-19591466
[Presentation] エタノールは樹状細胞由来からのIL-12産生能を低下させTh2応答を増強する。2009
- Author(s)
  石川文雄, 桑原卓, 田中ゆり子, 百瀬弥寿徳, 垣内史堂
- Organizer
  第20回日本生体防御学会
- Place of Presentation
  東京
- Year and Date
  2009-07-26
- Data Source
  KAKENHI-PROJECT-19591466
[Presentation] エタノール処理マウスの樹状細胞はTh2応答を増強する。2009
- Author(s)
  石川文雄, 桑原卓.田中ゆり子, 今井常彦, 百瀬弥寿徳, 垣内史堂
- Organizer
  第44回日本アルコール・薬物医学会
- Place of Presentation
  横浜
- Year and Date
  2009-09-08
- Data Source
  KAKENHI-PROJECT-19591466
[Presentation] Soluble protein antigen alone efficiently elicits T cell response in mutant mice lacking expression of CCL19 and CCL221(plt mice)2009
- Author(s)
  田中ゆり子, 桑原卓, 石川文雄, 垣内史堂
- Organizer
  第39回日本免疫学会
- Place of Presentation
  大阪
- Year and Date
  2009-12-02
- Data Source
  KAKENHI-PROJECT-19591466
[Presentation] 気道過敏症に対する免疫学的検討、プロジェクト発表2008
- Author(s)
  石川文雄, 関東裕美, 岡和之
- Organizer
  第131回東邦医学会例会
- Place of Presentation
  東京
- Year and Date
  2008-02-08
- Data Source
  KAKENHI-PROJECT-19591466
[Presentation] LAK療法と分子標的薬剤の併用効果2008
- Author(s)
  土井範子, 石川文雄, 片桐ゆり子, 竹下直樹, 森田俊介
- Organizer
  第81回日本生化学会大会
- Place of Presentation
  神戸
- Year and Date
  2008-12-09
- Data Source
  KAKENHI-PROJECT-19591466
[Presentation] Ethanol inhalation alters dendritic cell function and induces Th2-polarized immune response.2008
- Author(s)
  石川文雄
- Organizer
  第38回日本免疫学会
- Place of Presentation
  京都
- Data Source
  KAKENHI-PROJECT-19591466
[Presentation] CC-chemokine receptor 7 ligand are required for development of EAE through generating IL-23-dependent Th17 cells, and Keystone resort Colorado; January 2008.2008
- Author(s)
  Kuwabara T, Ishikawa F, Okada Y, Tanaka Y, Kakiuchi T.
- Organizer
  Keystone symposia, Chemokines and Chemokine receptors
- Place of Presentation
  Keystone, USA
- Year and Date
  2008-01-25
- Data Source
  KAKENHI-PROJECT-19591466
[Presentation] CCL19/CCL21 chemokines play a role in initiating immune response in the draining lymph node.2008
- Author(s)
  田中ゆり子, 石川文雄, 桑原卓, 垣内史堂
- Organizer
  第38回日本免疫学会総会・学術集会
- Place of Presentation
  京都
- Year and Date
  2008-12-01
- Data Source
  KAKENHI-PROJECT-19591466
[Presentation] エタノールール摂取によるTh2細胞への分化促進を介した抗原特異的IgE産生増強.2008
- Author(s)
  中里純子, 石川文雄, 桑原卓, 垣内史堂, 岸田勝
- Organizer
  第20回日本アレルギー学会
- Place of Presentation
  東京
- Year and Date
  2008-06-12
- Data Source
  KAKENHI-PROJECT-19591466
[Presentation] ケモカイン受容体CCR7の動態解析.2008
- Author(s)
  桑原卓, 石川文雄、田中ゆり子、垣内史堂
- Organizer
  第62回東邦医学会学術集会
- Place of Presentation
  東京
- Year and Date
  2008-10-05
- Data Source
  KAKENHI-PROJECT-19591466
[Presentation] 放射線ホルミシス効果の解析2008
- Author(s)
  石川文雄
- Organizer
  第62回東邦医学会総会
- Place of Presentation
  東京
- Data Source
  KAKENHI-PROJECT-19591466
[Presentation] 気道過敏症に対する免疫学的検討2008
- Author(s)
  石川文雄、関東裕美、岡和之
- Organizer
  第131回東邦医学会例会
- Place of Presentation
  東京
- Data Source
  KAKENHI-PROJECT-19591466
[Presentation] A role for CCL19 and CCL21 in experimental autoimmune encephalomyelitis.2008
- Author(s)
  桑原卓, 石川文雄, 田中ゆり子, 岡田弥生, 垣内史堂
- Organizer
  第19回日本生体防御学会
- Place of Presentation
  札幌
- Year and Date
  2008-07-12
- Data Source
  KAKENHI-PROJECT-19591466
[Presentation] CC chemokine receptor 7- ligands are required for development of EAE through generating iL-23-dependent Th17 cells.2008
- Author(s)
  桑原卓, 石川文雄, 田中ゆり子, 岡田弥生, 垣内史堂
- Organizer
  第38回日本免疫学会総会・学術集会
- Place of Presentation
  京都
- Year and Date
  2008-12-01
- Data Source
  KAKENHI-PROJECT-19591466
[Presentation] Etanol inhalation enhances OVA-induced airway hyper- sensitivity through Th2-polarizatin and IL-25 production.2008
- Author(s)
  Fumio Ishikawa, Taku Kuwabara, Yuriko Tanaka, Yayoi Okada, Terutaka Kakiuchi
- Organizer
  第38回日本免疫学会
- Place of Presentation
  京都
- Year and Date
  2008-12-03
- Data Source
  KAKENHI-PROJECT-19591466
[Presentation] A role for CCL19 and CCL21 in experimental autoimmune encephalo- myelitis.2007
- Author(s)
  Kuwabara T, Ishikawa F, Okada Y, Tanaka Y, Kakiuchi T.
- Organizer
  13th International Congreess of Immunology Rio De Janeiro
- Place of Presentation
  Brazil
- Year and Date
  2007-08-11
- Data Source
  KAKENHI-PROJECT-19591466
[Presentation] Ethanol inhalation alters dendritic cell function and induces Th2-polarized immune response.2007
- Author(s)
  Fumio Ishikawa, Taku Kuwabara, Yuriko Tanaka, Yayoi okada, Terutaka Kakiuchi
- Organizer
  第37回日本免疫学会
- Place of Presentation
  東京
- Year and Date
  2007-11-22
- Data Source
  KAKENHI-PROJECT-19591466
[Presentation] エタノールーによる気道過敏反応の増強について.2007
- Author(s)
  中里純子, 岸田勝、四宮範明、石川文雄, 岡田弥生、桑原卓, 垣内史堂
- Organizer
  第61回東邦医学会
- Place of Presentation
  東京
- Year and Date
  2007-11-08
- Data Source
  KAKENHI-PROJECT-19591466

1. OKADA Yayoi (60256758)

# of Collaborated Projects: 4 results

# of Collaborated Products: 9 results
2. KAKIUCHI Terutaka (40126024)

# of Collaborated Projects: 2 results

# of Collaborated Products: 0 results
3. MIYAZAKI Shuichi (30120314)

# of Collaborated Projects: 1 results

# of Collaborated Products: 4 results
4. KONDO Motonari (20594344)

# of Collaborated Projects: 1 results

# of Collaborated Products: 1 results
5. TANAKA Yuriko (40396685)

# of Collaborated Projects: 1 results

# of Collaborated Products: 1 results
6. KURAMOTO Shintarou (50057460)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
7. NAKAZAKI Haruhiro (00207747)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
8. YOSHIO Toshifumi (80057497)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
9. OKAJIMA Yukikazu (60104212)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
10. ITO Masatoshi (10057698)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
11. TAKEUCHI Yoshio (40130372)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
12. OTA Yasushi (40251285)

# of Collaborated Projects: 1 results

# of Collaborated Products: 2 results
13. 木村一郎 (10009996)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
14. 鈴木光也 (50302724)

# of Collaborated Projects: 1 results

# of Collaborated Products: 1 results
15. 池宮城慶寛 (50439931)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results

ISHIKAWA Fumio 石川 文雄

Research Projects

Research Products

Co-Researchers

Clarification of etiology elucidation of eosinophilic chronic sibusitis and making of the model mouse

Principal Investigator

Project Period (FY)

Research Category

Research Field

Research Institution

Suppression mechanisms of autoimmune diseases by SATB1

Principal Investigator

Project Period (FY)

Research Category

Research Field

Research Institution

Analysis of the CD80 up-regulation by low-dose ionizing radiation.Principal Investigator

Principal Investigator

Project Period (FY)

Research Category

Research Field

Research Institution

Immunological study and etiotropic development in monogenesis of Ankylosing spondylitis

Principal Investigator

Project Period (FY)

Research Category

Research Field

Research Institution

Development of the high sensitivity measurements for drug-allergy

Principal Investigator

Project Period (FY)

Research Category

Research Field

Research Institution

Serum cytokine levels and immunological function in patients with cancer

Principal Investigator

Project Period (FY)

Research Category

Research Field

Research Institution

[Journal Article] A case of refractory chronic rhinosinusitis with anti-desmoglein 3 IgG4 autoantibody2017

Author(s)

Journal Title

NAID

Data Source

[Journal Article] CCR7 ligands are required for development of experimental autoimmune encephalomyelitis through generating IL-23-dependent Th17 cells.2009

Author(s)

Journal Title

Data Source

[Journal Article] CCR7 ligands are required for development of experimental autoimmune encephalomyelitis through generating IL-23-dependent Th17 cells2009

Author(s)

Journal Title

Data Source

[Journal Article] Inhaled etanol increases antigen-specific IgE production via enhanced Th2 lineage differntiation2008

Author(s)

Journal Title

Data Source

[Journal Article] Inhaled etanol increases antigen-specific IgE production via enhanced Th2 lineage differntiation.2008

Author(s)

Journal Title

Data Source

[Journal Article] Effect of Fluoroquinolones on body temperature of mice.2008

Author(s)

Journal Title

Data Source

[Journal Article] Inhaled etanol increases antigen-specific IgE production viaenhanced Th2 lineage differntiation2008

Author(s)

Journal Title

Data Source

[Journal Article] Isolation and characterization of the N-linked oligosaccharides in nacrein from Pinctada fucata.2008

Author(s)

Journal Title

Data Source

[Journal Article] Effect of Fluoroquinolones on body temperature of mice.2008

Author(s)

Journal Title

Data Source

[Journal Article] Gr-1 high polumorphonuclear leukocytes and NK cells act via IL-15 to clear intracellular haemophilus influenzae in experimental murine peri-tonities and pneumonia2007

Author(s)

Journal Title

ISHIKAWA Fumio 石川文雄