IWAMOTO Aikichi 岩本愛吉

Researcher Number	10133076
Other IDs
Affiliation (based on the past Project Information) *help	2007 – 2008: The University of Tokyo, 医科学研究所, 教授 1994 – 2003: University of Tokyo, Institute of Medical Science, Professor, 医科学研究所, 教授 1996: NATIONAL INSTITUTE OF HEALTH AND INSTITUTE OF MEDICAL SCIENCE,UNIVERSITY OF TOKY, 医科学・研究所, 教授 1993: 東京大学, 医学部・細菌学, 助教授 1992 – 1993: 東京大学, 医学部(医), 助教授 … More 1992: 東大, 医・細菌学, 助教授 1991: 東京大学, 医学部・病原微生物学, 講師 1990: 東京大学, 医学部・医学科, 講師 1989 – 1990: 東京大学, 医学部(医), 講師 1988: 東京大学, 医学部医学科, 助手 Less
Review Section/Research Field	Principal Investigator Virology / Virology Except Principal Investigator Biological Sciences / 内科学一般 / General surgery / Radiation science
Keywords	Principal Investigator HIV / CTL / Fv-1 / neutralizing antibodies / HCV / hepatitis C virus / レトロウイルス / エピトープ / ラウス肉腫ウィルス / G Protein … More / Adenyl Cyclase / Morphological Conversion / XC cell / Rous sarcoma virus / アデニレートシクラーゼ / アデニレ-トシクラ-ゼ / 細胞形態変換 / GTP結合蛋白 / アデニル酸シクラ-ゼ / 形態変換 / XC細胞 / tetramer / epitope / vaccine / テトラマー / ワクチン / host factor / Mous leukemia virus / retrovirus / 宿主因子 / マウス白血病ウイルス / Env protein / Gag protein / Viral structural protein / Retrovirus / Measles virus / Env蛋白質 / Gag蛋白質 / ウイルス構造蛋白質 / 麻疹ウイルス / マウス白血病ウイルス / ネオマイシン耐性遺伝子 / 遺伝子組換え / ウシパピローマウィルス / HIV病態進行 / TCR レパートリー / T細胞受容体(TCR) / 細胞傷害性T細胞(CTL) / 抗原認識 / 細胞傷害性T 細胞 (CTL) / HLA / envelope gene / dominant negative mutaut / murine leukemia virus / DNAメチル化 … More Except Principal Investigator 抗体 / DNA / がん / thrombomodulin / tissue plasminogen activator / adenovirus / パーフォリン / PCR法 / 疣贅様表皮発育異常症 / 子宮頚部 / Molecular biology / Drug-resistance / Hospital-acquired infections / Pneumocystis carinii / 分子生物学 / 薬剤耐性 / 院内感染 / ニューモシスチス・カリニ / small caliber vascular prosthesis / endothelial cell / hybrid-type vascular prosthesis / gene therapy / vetrovirus / retrovirus / 小口径人工血管 / 血管内皮細胞 / ハイブリッド型人工血管 / 遺伝子治療 / インターフェロンγ / CD8 / CD4 / Tリンパ球 / HIV感染者 / インターフェロン / キラーTリンパ球 / ヘルパーTリンパ球 / HIV感染症 / EPL法 / MRI / AIDS / 脾臓病理 / 拡散強調画像 / EPI法 / ウイルス膜融合 / ウイルス侵入 / 持続感染 / 制御遺伝子 / センダイウイルスペクター / シアル酸 / V3 / V2 / 病態 / 体内変異 / HIV / センダイウイルスベクター / ケモカイン受容体 / ケモカイン / エンベロープ糖蛋白 / HIV-変異 / エイズ病態 / 子宮頸部 / ヒトパピローマウィルス / ヒトパピローマウイルス / 上皮内腫瘍 / パピロ-マウイルス Less

Analysis of HIV-specific cellular immune response and antigen presentation in HIV infectionPrincipal Investigator
- Principal Investigator
  
  IWAMOTO Aikichi
- Project Period (FY)
  2007 – 2008
- Research Category
  
  Grant-in-Aid for Scientific Research (B)
- Research Field
  
  Virology
- Research Institution
  The University of Tokyo
Basic and Clinical Research for Development of Therapeutic Peptide Vaccine for HIV InfectionPrincipal Investigator
- Principal Investigator
  
  IWAMOTO Aikichi
- Project Period (FY)
  2002 – 2003
- Research Category
  
  Grant-in-Aid for Scientific Research (A)
- Research Field
  
  Virology
- Research Institution
  The University of Tokyo
HIV特異的Tリンパ球の機能異常とその機序の解析
- Principal Investigator
  
  中村哲也
- Project Period (FY)
  2001
- Research Category
  
  Grant-in-Aid for Scientific Research on Priority Areas (A)
- Review Section
  
  Biological Sciences
- Research Institution
  The University of Tokyo
HIV特異的Tリンパ球機能の質的、量的解析とHIV感染症の病態
- Principal Investigator
  
  中村哲也
- Project Period (FY)
  2000 – 2001
- Research Category
  
  Grant-in-Aid for Scientific Research on Priority Areas (A)
- Review Section
  
  Biological Sciences
- Research Institution
  The University of Tokyo
Molecular Biological Study on Hospital-Acquired Infections and Drug-Resistance of Pneumocystis carinii
- Principal Investigator
  
  TAKAHASHI Takashi
- Project Period (FY)
  1999 – 2000
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Research Field
  
  内科学一般
- Research Institution
  The University of Tokyo
エイズの病態と制御に関する基礎研究柱2.病態のウイルス学的基盤
- Principal Investigator
  
  永井美之
- Project Period (FY)
  1997
- Research Category
  
  Grant-in-Aid for Scientific Research on Priority Areas
- Research Institution
  The University of Tokyo
EPI法拡散強調画像を用いた脾臓病理のMR診断に関する研究-AIDSを中心に-
- Principal Investigator
  
  NAKAMURA Tetsuya
- Project Period (FY)
  1997 – 1998
- Research Category
  
  Grant-in-Aid for Exploratory Research
- Research Field
  
  Radiation science
- Research Institution
  The University of Tokyo
Mechanism of viral escape from host Fv-1 restrictionPrincipal Investigator
- Principal Investigator
  
  IWAMOTO Aikichi
- Project Period (FY)
  1994 – 1995
- Research Category
  
  Grant-in-Aid for General Scientific Research (B)
- Research Field
  
  Virology
- Research Institution
  The University of Tokyo
APPLICATION OF GENETRANSFER TECHNIQUE TO ENDOTHELIAL CELL SEEDED VASCULAR PROSTHESIS
- Principal Investigator
  
  MIYATA Tetsuro
- Project Period (FY)
  1994 – 1996
- Research Category
  
  Grant-in-Aid for Scientific Research (B)
- Research Field
  
  General surgery
- Research Institution
  UNIVERSITY OF TOKYO
ヒトがんへのパピローマウィルスの関与--疫学的研究を中心に--
- Principal Investigator
  
  石橋正英
- Project Period (FY)
  1993
- Research Category
  
  Grant-in-Aid for Cancer Research
- Research Institution
  Aichi Cancer Center Research Institute
RNA腫瘍ウイルスの増殖をトランスに抑制するエンベロ-プ蛋白質変異体の解析Principal Investigator
- Principal Investigator
  
  岩本愛吉
- Project Period (FY)
  1993
- Research Category
  
  Grant-in-Aid for Cancer Research
- Research Institution
  The University of Tokyo
Development of the assay system for netralizing antibodies agaist hepatitis C virusPrincipal Investigator
- Principal Investigator
  
  IWAMOTO Aikichi
- Project Period (FY)
  1993 – 1994
- Research Category
  
  Grant-in-Aid for Developmental Scientific Research (B)
- Research Field
  
  Virology
- Research Institution
  The University of Tokyo
ヒトがんへのパピローマウイルスの関与ー疫学的研究を中心に
- Principal Investigator
  
  石橋正英
- Project Period (FY)
  1992
- Research Category
  
  Grant-in-Aid for Cancer Research
- Research Institution
  Aichi Cancer Center Research Institute
ANALYSIS OF FUNCTIONAL PROPERTIES OF VIRALPrincipal Investigator
- Principal Investigator
  
  IWAMOTO Aikichi
- Project Period (FY)
  1992 – 1993
- Research Category
  
  Grant-in-Aid for General Scientific Research (C)
- Research Field
  
  Virology
- Research Institution
  University of Tokyo
ヒトがんへのパピロ-マウイルスの関与ーー疫学的研究を中心にーー
- Principal Investigator
  
  石橋正英
- Project Period (FY)
  1991
- Research Category
  
  Grant-in-Aid for Cancer Research
- Research Institution
  Aichi Cancer Center Research Institute
レトロウィルスで癌化した細胞におけるエピジェネティックな変化Principal Investigator
- Principal Investigator
  
  岩本愛吉
- Project Period (FY)
  1990
- Research Category
  
  Grant-in-Aid for Cancer Research
- Research Institution
  The University of Tokyo
DNAの構造変化とそれに及ぼす宿主因子に関する分子生物学的基礎研究Principal Investigator
- Principal Investigator
  
  岩本愛吉
- Project Period (FY)
  1988
- Research Category
  
  Grant-in-Aid for Cancer Research
- Research Institution
  The University of Tokyo
Molecular biological analysis of morphological conversion of cellsPrincipal Investigator
- Principal Investigator
  
  IWAMATO Aikichi
- Project Period (FY)
  1988 – 1990
- Research Category
  
  Grant-in-Aid for General Scientific Research (C)
- Research Field
  
  Virology
- Research Institution
  The University of Tokyo

All 2009 2008 2007 Other

All Journal Article Presentation

[Journal Article] Highly restricted T-cell receptor repertoire in the CD8+ T-cell response against an HIV-1 epitope with a stereotypic amino acid substitution2009
- Author(s)
  Miyazaki, E., Kawana-Tachikawa, A., Tomizawa, M., Nunoya J-I., Odawara T., Fujii, T., Shi, Y., Gao G.F., Iwamoto, A.
- Journal Title
  
  AIDS 23
  
  Pages: 651-660
- Data Source
  KAKENHI-PROJECT-19390130
[Journal Article] Rehsusmacaque : a tight homodimeric CD8alpha/alpha2009
- Author(s)
  Zong, L., Chen, Y., Peng, H., Gao, F., Iwamoto, A., Gao, GF.
- Journal Title
  
  Proteins : Structure, Function and Bioinformatics 75
  
  Pages: 241-244
- Data Source
  KAKENHI-PROJECT-19390130
[Journal Article] Activation of HIV-1 Gag-specific CD8+ T cells by yeast-derived VLP-pulsed dendritic cells is influenced by the level of mannose on the VLP antigen2009
- Author(s)
  Mizukoshi, F., Yamamoto, T., Mitsuki Y.Y., Terahara, K., Kawana-Tachikawa, A., Kobayashi, K., Iwamoto A., Morikawa, Y., Tsunetsugu-Yokota, Y.
- Journal Title
  
  Microbes Infection 11
  
  Pages: 191-19
- Data Source
  KAKENHI-PROJECT-19390130
[Journal Article] Comparison between Sendai virus and Adenovirus vectors in induction of HIV-1 genes into human dendritic cells2008
- Author(s)
  Hosoya, N., Miura, T., Kawana-Tachikawa, A., Shioda, T., Odawara, T.,Nakamura, T., Kitamura, Y., Kano, M., Kato, A., Hironaka, T., Hasegawa, M.,Nagai, Y., Iwamoto, A.
- Journal Title
  
  J. Medical Virology 80
  
  Pages: 373-382
- Data Source
  KAKENHI-PROJECT-19390130
[Journal Article] Erythromycin derivatives inhibit HIV-1 replication in macrophages through modulation of MAPK activity to induce small isoforms of C/EBPbeta2008
- Author(s)
  Komuro, I., Sunazuka, T., Akagawa, K.S., Yokota, Y., Iwamoto, A., Omura, S.
- Journal Title
  
  Proc. Natl. Acad. USA 105
  
  Pages: 12509-12514
- Data Source
  KAKENHI-PROJECT-19390130
[Journal Article] Vpr in plasma of HIV-1-positive patients is correlated with the HIV-1 RNA titers2007
- Author(s)
  Hoshino, S., Sun, B., Konishi, M., Shimura, M., Segawa, T. Hagiwara, Y.,Koyanagi, Y., Iwamoto, A., Mimaya, J., Terunuma, H., Kano, S., Ishizaka, Y.
- Journal Title
  
  AIDS Research and Human Retroviruses 23
  
  Pages: 391-397
- Data Source
  KAKENHI-PROJECT-19390130
[Journal Article] The polymorphisms in DC-SIGNR affect susceptibility to HIV-1infection2007
- Author(s)
  Wichukchinda, N., Kitamura, Y., Rojanawiwat, A., Nakayama, E.E., Song, H.,Pathipvanich, P., Auwanit, W., Sawanpanyalert, P., Iwamoto, A., Shioda, T., Ariyoshi, K.
- Journal Title
  
  Research and Human Retroviruses 23
  
  Pages: 686-692
- Data Source
  KAKENHI-PROJECT-19390130
[Journal Article] Polymorphisms in CCR5 chemokine receptorgene in Japan. International J2007
- Author(s)
  Liu, H., Nakayama, E.E., Theodorou, I., Nagai, Y., Likanonsakul, S., Wasi, C., Debre, P. Iwamoto, A., Shioda, T.
- Journal Title
  
  Immunogenetics 34
  
  Pages: 325-335
- Data Source
  KAKENHI-PROJECT-19390130
[Journal Article] Wild type and H43Y variant of human TRIM5α show similar anti-human immunodeficiency virus type 1 activity both in vivo and in vitro2007
- Author(s)
  Nakayama, E.E., Carpentier, W., Costagliola, D., Shioda, T., Iwamoto, A., Debre, P., Yoshimura, K., Autran, B., Matsushita, S., Theodorou, I.
- Journal Title
  
  International J.Immunogenetics 59
  
  Pages: 511-515
- Data Source
  KAKENHI-PROJECT-19390130
[Journal Article] A three-base-deletion polymorphism in the upstream non-coding regionof human interleukin 7 (IL-7) gene could enhance levels of IL-7 expression2007
- Author(s)
  Song, H., Nakayama, E.E., Likanonsakul, S., Wasi, C., Iwamoto, A., Shioda, T.
- Journal Title
  
  International J. Immunogenetics 34
  
  Pages: 107-113
- Data Source
  KAKENHI-PROJECT-19390130
[Journal Article] Generation of recombinant monoclonal antibodies against an immunodominant HLA-A*2402-restricted HIV-1 CTL epitope
- Author(s)
  Nunoya, J-I., Nakashima, T., Kawana-Tachikawa, A., Kiyotani, K., Ito, Y., Sugimura, K., Iwamoto, A.
- Journal Title
  
  AIDS Research and Human Retroviruses (In press)
- Data Source
  KAKENHI-PROJECT-19390130
[Journal Article] Pneumocystis jiroveci pneumonia in an AIDS patient : Unusual manifestation of multiple nodules with multiloculated cavities
- Author(s)
  Maeda, T., Oyaizu, N., Endo, T., Odawara, T., Nakamura, T., Iwamoto, A., Fujii, T.
- Journal Title
  
  European Journalof Radiology (In Press)
- Data Source
  KAKENHI-PROJECT-19390130
[Presentation] Japan and infectious diseases:A histourical view.2008
- Author(s)
  Iwamoto, A.
- Organizer
  APRU WorldInstitute Workshop,"Strengthening Public Health Systems in the Pacific Rim:The Role of Research Universities in Responding to Aging & Chronic Diseases, Infectious Disease and Health Security Issues."
- Place of Presentation
  東京
- Data Source
  KAKENHI-PROJECT-19390130
[Presentation] "Japan and infectious diseases : A historical view." APRU WorldInstitute Workshop2008
- Author(s)
  Iwamoto, A
- Organizer
  Strengthening Public Health Systems in the Pacific Rim : TheRole of Research Universities in Responding to Aging & Chronic Diseases, Infectious Disease and Health Security Issues
- Place of Presentation
  Tokyo
- Data Source
  KAKENHI-PROJECT-19390130
[Presentation] Antigen presentation and recognition : A tale of immunogenic HIV-1 CTL epitope in Japanese population with high HLA-A24 positivity2007
- Author(s)
  Iwamoto, A.
- Organizer
  International Symposium on Basic and Applied Immunology
- Place of Presentation
  北京(中国)
- Data Source
  KAKENHI-PROJECT-19390130
[Presentation] HIV epidemic in highly HLA-A24-positive Japanese population2007
- Author(s)
  Iwamoto, A.
- Organizer
  International Conference for Bioeconomy (BioEco2007)
- Place of Presentation
  天津(中国)
- Data Source
  KAKENHI-PROJECT-19390130
[Presentation] A tale of HIV epidemic among highly HLA-A24-positive Japanesepopulation2007
- Author(s)
  Iwamoto, A.
- Organizer
  The 7th Awaji International Forum on Infection and Immunity
- Place of Presentation
  淡路島
- Data Source
  KAKENHI-PROJECT-19390130
[Presentation] Monitoring and adherence of antiretroviral therapy. In SkillsBuilding Workshop on clinical management of HIV infection and antiretroviral therapy2007
- Author(s)
  Iwamoto, A
- Organizer
  The 8th International Congress on AIDS in Asia and the Pacific
- Place of Presentation
  Colombo
- Data Source
  KAKENHI-PROJECT-19390130
[Presentation] HIV epidemic in highly HLA-A24-positive Japanese population2007
- Author(s)
  Iwamoto, A
- Organizer
  2007 International Conference for Bioeconomy (BioEco2007)
- Place of Presentation
  Tianjin
- Data Source
  KAKENHI-PROJECT-19390130
[Presentation] HIV treatment and complications2007
- Author(s)
  Iwamoto, A
- Organizer
  International Conference on AIDS/HIV. China Association of Chinese Medicine AIDS Branch
- Place of Presentation
  Zhengzhou, Henan,China
- Data Source
  KAKENHI-PROJECT-19390130
[Presentation] Monitoring and adherence of antiretroviral therapy2007
- Author(s)
  Iwamoto, A.
- Organizer
  The 8th International Congress on AIDS in Asia and the Pacific
- Place of Presentation
  Colombo (Sri Lanka)
- Data Source
  KAKENHI-PROJECT-19390130
[Presentation] HIV treatment and complications2007
- Author(s)
  Iwamoto, A.
- Organizer
  International Conference on AIDS/HIV. China Association of Chinese Medicine AIDS Branch
- Place of Presentation
  鄭州(中国)
- Data Source
  KAKENHI-PROJECT-19390130
[Presentation] Antigen presentation and recognition : A tale of immunogenic HIV-1 CTL epitope in Japanese population with high HLA-A24 positivity2007
- Author(s)
  Iwamoto, A
- Organizer
  International Symposium on Basic and Applied Immunology
- Place of Presentation
  Beijing, China
- Data Source
  KAKENHI-PROJECT-19390130
[Presentation] A tale of HIV epidemic among highly HLA-A24-positive Japanese population2007
- Author(s)
  Iwamoto, A
- Organizer
  The 7th Awaji International Forum on Infection and Immunity
- Place of Presentation
  Awajishima
- Data Source
  KAKENHI-PROJECT-19390130

1. YOSHIKURA Hiroshi (60012754)

# of Collaborated Projects: 7 results

# of Collaborated Products: 0 results
2. NAKAMURA Tetsuya (30189047)

# of Collaborated Projects: 4 results

# of Collaborated Products: 0 results
3. 藤永惠 (10045338)

# of Collaborated Projects: 3 results

# of Collaborated Products: 0 results
4. 石橋正英 (70029776)

# of Collaborated Projects: 3 results

# of Collaborated Products: 0 results
5. 川名尚 (90010272)

# of Collaborated Projects: 3 results

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6. 神田忠仁 (60134615)

# of Collaborated Projects: 3 results

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7. 松倉俊彦 (70100097)

# of Collaborated Projects: 3 results

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8. TACHIKAWA Ai (10396880)

# of Collaborated Projects: 1 results

# of Collaborated Products: 4 results
9. YANAGI Yusuke (40182365)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
10. SHUIMIZU Yohko (00142357)

# of Collaborated Projects: 1 results

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11. MIYATA Tetsuro (70190791)

# of Collaborated Projects: 1 results

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12. SATO Osamu (40170724)

# of Collaborated Projects: 1 results

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13. TAKAHASHI Takashi (00292855)

# of Collaborated Projects: 1 results

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14. NAKAMURA Yoshikazu (40114590)

# of Collaborated Projects: 1 results

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15. ODAWARA Takashi (40204218)

# of Collaborated Projects: 1 results

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16. 北村義浩 (10202037)

# of Collaborated Projects: 1 results

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17. 永井美之 (20022874)

# of Collaborated Projects: 1 results

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18. 伊藤康彦 (00022872)

# of Collaborated Projects: 1 results

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19. 星野洪郎 (00107434)

# of Collaborated Projects: 1 results

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20. 原田信志 (60173085)

# of Collaborated Projects: 1 results

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21. 生田和良 (60127181)

# of Collaborated Projects: 1 results

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22. 淺井佐江 (10159353)

# of Collaborated Projects: 1 results

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23. 吉川宏起 (10272494)

# of Collaborated Projects: 1 results

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24. 戸辺公子 (50262077)

# of Collaborated Projects: 1 results

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25. 半田宏 (80107432)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
26. 池田日出男 (10012775)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
27. 小山博之 (10241994)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
28. 高木淳彦 (50092979)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
29. 木村秀生

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results

IWAMOTO Aikichi 岩本 愛吉

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Co-Researchers

Analysis of HIV-specific cellular immune response and antigen presentation in HIV infectionPrincipal Investigator

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Basic and Clinical Research for Development of Therapeutic Peptide Vaccine for HIV InfectionPrincipal Investigator

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Mechanism of viral escape from host Fv-1 restrictionPrincipal Investigator

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RNA腫瘍ウイルスの増殖をトランスに抑制するエンベロ-プ蛋白質変異体の解析Principal Investigator

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Development of the assay system for netralizing antibodies agaist hepatitis C virusPrincipal Investigator

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ANALYSIS OF FUNCTIONAL PROPERTIES OF VIRALPrincipal Investigator

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IWAMOTO Aikichi 岩本愛吉