KOBAYASHI Yoshiro 小林芳郎

… Alternative Names

Researcher Number	10134610
Other IDs
Affiliation (Current)	2019: 東邦大学, 理学部, 教授
Affiliation (based on the past Project Information) *help	2007 – 2017: 東邦大学, 理学部, 教授 1995 – 2005: 東邦大学, 理学部, 教授 1986 – 1987: 東京大学, 薬学部, 助手
Review Section/Research Field	Principal Investigator Biological pharmacy / Biological pharmacy Except Principal Investigator Biological pharmacy / Bioorganic chemistry / Biological Sciences / Immunology / Functional biochemistry / Biological pharmacy
Keywords	Principal Investigator 好中球 / マクロファージ / アポトーシス / neutrophil / ケモカイン / サイトカイン / インターロイキン1α / プロセシング / 分泌 / release … More Except Principal Investigator アポトーシス / マクロファージ / 好中球 / inflammation / 老化 / 炎症 / 貪食 / ケージド化合物 / Caged compounds / p33ING2 / p53 / p47ING3 / p29ING4 / p28ING5 / 免疫化学 / 貪食応答 / 免疫学 / necrosis / neutrophil / chemokine / DAMPs / ケモカイン / インターロイキン8 / 単球走化活性化因子 / 単球 / 炎症反応 / HIV感染 / レセプター / 単球走活性化因子 / 糸球体腎炎 / 急性呼吸窮迫症候群 / Chemokine / interleukin-8 / MCAF / MCP-1 / neutrophils / monocytes / HIV infection / receptor / Caged化合物 / 免疫応答 / 細胞障害性 / 糖を修飾した2-ニトロベンジル / 細胞認識 / ロイシルロイシンメチルエステル / 糖を修飾したニトロベンジル基 / マクロファージ系細胞株 / 5-O-(β-Glucopyranosyl)-2-Nitrobenzyl / Apoptosis / Immune responce / Cytotoxic activity / Sugar-modified 2-nitrobenzyil / Cell recognition / Macrophage / インターロイキン1α / 細胞内局在 / リン酸化 / 核移行シグナル / 融合タンパク質 / interleukin 1alpha / inthacellular localization / phosphorylation / nuclear localization signal / fusion protein / ポリエステル型デンドリマー / ダイヴァージェント法 / ドラッグデリバリーシステム / 細胞認識能 / アセト酢酸エステル / アクリル酸エステル / AB_2型ビルディングブロック / EDCI-DMAP / デンドロン / ビルディングブロック / DCC-DPTS / マイケル型付加反応 / ヒドロキシアセトフェノン / Polyester-type dendrimers / Divergent method / Drug delivery systems / Cell recognition ability / Acetoacetic esters / Acrylic esters / T細胞ハイブリドーマ / マクロファージハイブリドーマ / リンホカイン / モノカイン / リンホトキシン / マクロファージ活性化因子 / 癌細胞壊死因子 / 殺腫瘍細胞因子 / 抗体産生増強因子 / 殺腫瘍活性 / NK細胞活性化因子 / 腫瘍壊死因子(TNF) / Lymphokine / Monokine / T cell hybridoma / Macrophage hybridoma / Lymphotoxin / Macrophage activating factor / 死細胞 / アポトーシス細胞 Less

The analysis of mechanism in the serious inflammatory responses induced by dead cells as aging.
- Principal Investigator
  
  NAGATA Kisaburo
- Project Period (FY)
  2015 – 2017
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Research Field
  
  Biological pharmacy
- Research Institution
  Toho University
The effect of aging on dead cells induced inflamatory responses and analysis of its mechanisms
- Principal Investigator
  
  NAGATA Kisaburo
- Project Period (FY)
  2012 – 2014
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Research Field
  
  Biological pharmacy
- Research Institution
  Toho University
Resolution of inflammation through macrophage response to apoptotic neutrophilsPrincipal Investigator
- Principal Investigator
  
  KOBAYASHI Yoshiro
- Project Period (FY)
  2009 – 2011
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Research Field
  
  Biological pharmacy
- Research Institution
  Toho University
The role of DAMPs on induction and termination of inflammatory responses induced by necrotic cells.
- Principal Investigator
  
  NAGATA Kisaburo
- Project Period (FY)
  2009 – 2011
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Research Field
  
  Biological pharmacy
- Research Institution
  Toho University
Analysis and Application of activating mechanisms of innate immunity by neutrophils.
- Principal Investigator
  
  NAGATA Kisaburo
- Project Period (FY)
  2007 – 2008
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Research Field
  
  Biological pharmacy
- Research Institution
  Toho University
Responses in a coculture of macrophages, immature dendritic cells and apoptotic cellsPrincipal Investigator
- Principal Investigator
  
  KOBAYASHI Yoshiro
- Project Period (FY)
  2004 – 2005
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Research Field
  
  Biological pharmacy
- Research Institution
  Toho University
p53コアクチベーターINGファミリーのがん細胞中における変異および機能の解析
- Principal Investigator
  
  長島誠
- Project Period (FY)
  2003
- Research Category
  
  Grant-in-Aid for Scientific Research on Priority Areas
- Review Section
  
  Biological Sciences
- Research Institution
  Toho University
In vivo role of the responce of macrophages after phagocytosis of appptotic cellsPrincipal Investigator
- Principal Investigator
  
  KOBAYASHI Yoshiro
- Project Period (FY)
  2002 – 2003
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Research Field
  
  Biological pharmacy
- Research Institution
  Toho University
Design and Synthesis of Novel Polyester-type Dendrimers Having Cell Recognition Ability.
- Principal Investigator
  
  IWAMURA Michiko
- Project Period (FY)
  2001 – 2003
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Research Field
  
  Bioorganic chemistry
- Research Institution
  Toho University
Pathological Significance of the response of macrophages after phagocytosis of apoptotic cellsPrincipal Investigator
- Principal Investigator
  
  KOBAYASHI Yoshiro
- Project Period (FY)
  1999 – 2000
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Research Field
  
  Biological pharmacy
- Research Institution
  Toho University
Regulatory Mechanism of Processing and Release of IL-lalphaPrincipal Investigator
- Principal Investigator
  
  KOBAYASHI Yoshiro
- Project Period (FY)
  1997 – 1998
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Research Field
  
  Biological pharmacy
- Research Institution
  Toho University
Role of Phosphorylation on Intracellular Localization of Interleukin 1alpha
- Principal Investigator
  
  WATANABE Naoko
- Project Period (FY)
  1997 – 1998
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Research Field
  
  Functional biochemistry
- Research Institution
  Toho University
Pathophysiological and pharmacological studies on chemokines
- Principal Investigator
  
  MATSUSHIMA Kouji
- Project Period (FY)
  1996 – 1997
- Research Category
  
  Grant-in-Aid for international Scientific Research
- Research Field
  
  Immunology
- Research Institution
  University of Tokyo
Development and application of novel caged compounds for clucidation of immune responce
- Principal Investigator
  
  IWAMURA Michiko
- Project Period (FY)
  1996 – 1997
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Research Field
  
  Bioorganic chemistry
- Research Institution
  Toho University
Coupling mechanism of processing and release of interleukin 1Principal Investigator
- Principal Investigator
  
  KOBAYASHI Yoshiro
- Project Period (FY)
  1995 – 1996
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Research Field
  
  Biological pharmacy
- Research Institution
  Toho University
Biochemical studies and medical application of immunoregulatory factors
- Principal Investigator
  
  OSAWA Toshiaki
- Project Period (FY)
  1985 – 1987
- Research Category
  
  Grant-in-Aid for General Scientific Research (A)
- Research Field
  
  Biological pharmacy
- Research Institution
  The University of Tokyo

All 2017 2016 2015 2014 2012 2011 2010 2009 2008 2007 2005 2004 Other

All Journal Article Presentation

[Journal Article] Skewing of peritoneal resident macrophages toward M1-like is involved in enhancement of inflammatory responses induced by secondary necrotic neutrophils in aged mice.2016
- Author(s)
  Takahashi R, Ishigami A, Kobayashi Y, Nagata K.
- Journal Title
  
  Cellular Immunol.
  
  Volume: 304-305 Pages: 44-48
- DOI
  10.1016/j.cellimm.2016.03.001
- Peer Reviewed / Acknowledgement Compliant
- Data Source
  KAKENHI-PROJECT-15H04505, KAKENHI-PROJECT-15K07949
[Journal Article] Suppression of macrophage-mediated phagocytosis of apoptotic cells by soluble β-glucan due to a failure of PKC-βII translaction.2016
- Author(s)
  Sekiguchi, S., Tomisawa, Y., Ohki, T., Tsuboi, K., Nagata, K., and Kobayashi, Y.
- Journal Title
  
  Int. Immunopharm.
  
  Volume: 31 Pages: 195-199
- DOI
  10.1016/j.intimp.2015.12.028
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-15K07949
[Journal Article] Attenuated phagocytosis of secondary necrotic neutrophils by macrophages in aged and SMP30 knockout mice.2016
- Author(s)
  1.Takahashi, R., Totsuka, S., Ishigami, A., Kobayashi Y., and Nagata, K.
- Journal Title
  
  Geriatr Gerontol Int.
  
  Volume: 17 Pages: 1111-1111
- DOI
  10.1111/ggi.12436
- Peer Reviewed / Acknowledgement Compliant
- Data Source
  KAKENHI-PROJECT-24590100, KAKENHI-PROJECT-15K07949, KAKENHI-PROJECT-15H04505
[Journal Article] Suppression of MIP-2 production by annexin A1 and A4 during coculturing of macrophages with late apoptotic human peripheral blood neutrophils2012
- Author(s)
  Iwasa, T., Takahashi, R., Nagata, K., and Kobayashi, Y.
- Journal Title
  
  Biochemica et Biophysica Acta
  
  Volume: 1822 Pages: 204-211
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-21590078
[Journal Article] Apoptotic neutrophils and nitric oxide regulate cytokine production by IFN-g-stimulated macrophages2011
- Author(s)
  Shibata, T., Nagata, K., and Kobayashi, Y.
- Journal Title
  
  Cytokine
  
  Volume: 53 Pages: 191-195
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-21590078
[Journal Article] Regulation of the estrous cycle by neutrophils via opioid peptides2011
- Author(s)
  Sasaki, S., Tamaki, Y., Nagata, K., and Kobayashi, Y.
- Journal Title
  
  J. Immunol
  
  Volume: 187 Pages: 774-780
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-21590078
[Journal Article] The importance of infiltrating neutrophils in SDF-1 production leading to regeneration of the thymus after whole-body X-irradiation2011
- Author(s)
  Nakayama, E., Shiratsuchi, Y., Kobayashi, Y, Nagata, K.
- Journal Title
  
  Cellular Immunol.
  
  Volume: 268 Pages: 24-28
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-21590078
[Journal Article] Apoptotic neutrophils and nitric oxide regulate cytokine production by IFN-γ-stimulated macrophages.2011
- Author(s)
  Shibata, T., Nagata, K., Kobayashi, Y.
- Journal Title
  
  Cytokine
  
  Volume: 53 Pages: 191-195
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-21590078
[Journal Article] The importance of infiltrating neutrophils in SDF-1 production leading to regeneration of the thymus after whole-body X-irradiation2011
- Author(s)
  中山恵美、白土佳子、小林芳郎、永田喜三郎
- Journal Title
  
  Cellular Immunology
  
  Volume: 268 Pages: 24-28
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-21590077
[Journal Article] The importance of infiltrating neutrophils in SDF-1 production leading to regeneration of the thymus after whole-body X-irradiation2011
- Author(s)
  Nakayama, E., Shiratsuchi, Y., Kobayashi, Y., and Nagata, K.
- Journal Title
  
  Cellular Immunol
  
  Volume: 268 Pages: 24-28
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-21590078
[Journal Article] Regulation of the estrous cycle by neutrophils via opioid peptides2011
- Author(s)
  Sasaki, S., Tamaki, Y., Nagata, K., Kobayashi, Y.
- Journal Title
  
  J.Immunol.
  
  Volume: 187 Pages: 74-780
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-21590078
[Journal Article] Interleukin-9 Receptor Gene is Transcriptionally Regulated by Nucleolin in T-Cell Lymphoma Cells2011
- Author(s)
  Yi, S., Kakinuma, S., Nishimura, M., Kobayashi, Y., Nagata, K., and Shimada, Y
- Journal Title
  
  Molecular Carcinogenesis
  
  Volume: (現在Web公開のみ)
- DOI
  10.1002/mc.20834
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-21590078
[Journal Article] Apoptotic neutrophils and nitric oxide regulate cytokine production by IFN-γ-stimulated macrophages2011
- Author(s)
  柴田岳彦、永田喜三郎、小林芳郎
- Journal Title
  
  Cytokine
  
  Volume: 53 Pages: 191-195
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-21590077
[Journal Article] The mechanism underlying the appearance of late apoptotic neutrophils and subsequent TNF-α production at a late stage during Staphylococcus aureus bioparticle-induced peritoneal inflammation in inducible NO synthase-deficient mice2010
- Author(s)
  Shibata, T., Nagata, K., and Kobayashi, Y.
- Journal Title
  
  Biochemica et Biophysica Acta
  
  Volume: 1802 Pages: 1105-1111
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-21590078
[Journal Article] The mechanism underlying the appearance of late apoptotic neutrophils and subsequent TNF-α production at a late stage during Staphylococcus aureus bioparticle-induced peritoneal inflammation in inducible NO synthase-deficient mice.2010
- Author(s)
  Shibata, T., Nagata, K., Kobayashi, Y.
- Journal Title
  
  Biochemica et Biophysica Acta.
  
  Volume: 1802 Pages: 35-40
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-21590078
[Journal Article] The mechanism underlying the appearance of late apoptotic neutrophils and subsequent TNF-α production at a late stage during Staphylococcus aureus bioparticle-induced peritoneal inflammation in inducible NO synthase-deficient mice2010
- Author(s)
  柴田岳彦、永田喜三郎、小林芳郎
- Journal Title
  
  Biochimica et Biophysica Acta
  
  Volume: 1802 Pages: 1105-1111
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-21590077
[Journal Article] Characterization of a cDNA encoding guinea pig I3 associated with the delayed-type hypersensitivity reaction2009
- Author(s)
  中田・津久井久美子、小林芳郎、渡辺直子
- Journal Title
  
  Zoolog Sci
  
  Volume: 26 Pages: 617-622
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-21590077
[Journal Article] Regulation of the estrous cycle by neutrophil infiltration into the vagina2009
- Author(s)
  Sasaki, S., Nagata, K., Kobayashi, Y.
- Journal Title
  
  Biochem.Biophys.Res.Commun. 382
  
  Pages: 35-40
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-21590078
[Journal Article] 遅延型過敏症に関連したモルモットI3 cDNAの特徴2009
- Author(s)
  中田・津久井久美子, 小林芳郎, 渡辺直子
- Journal Title
  
  Zoolog Sci 26
  
  Pages: 617-622
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-21590077
[Journal Article] Regulation of the estrous cycle by neutrophil infiltration into the vagina2009
- Author(s)
  佐々木宗一郎、永田喜三郎、小林芳郎
- Journal Title
  
  Biochem Biophys Res Commun
  
  Volume: 382 Pages: 35-40
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-21590077
[Journal Article] 膣浸潤好中球による性周期の調節2009
- Author(s)
  佐々木宗一郎, 永田喜三郎, 小林芳郎
- Journal Title
  
  Biochem Biophys Res Commun 382
  
  Pages: 35-40
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-21590077
[Journal Article] Regulation of the estrous cycle by neutrophil infiltration into the vagina2009
- Author(s)
  Sasaki, S., Nagata, K., and Kobayashi, Y.
- Journal Title
  
  Biochem. Biophys. Res. Commun
  
  Volume: 382 Pages: 35-40
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-21590078
[Journal Article] Neutrophils and monocytes transport tumor cell antigens from the peritoneal cavity to secondary lymphoid tissues2008
- Author(s)
  Terasawa, M., Nagata, K., and Kobayashi, Y
- Journal Title
  
  Biochem. Biophys. Res. Commun 377
  
  Pages: 589-594
- Data Source
  KAKENHI-PROJECT-19590083
[Journal Article] Cytokine production by M-CSF- and GM-CSF-induced mouse bone marrow-derived macrophages upon coculturing with late apoptotic cells.2008
- Author(s)
  Yamazaki, T., Nagata, . K., Kobayashi, Y.
- Journal Title
  
  Cellular Immunol. 251
  
  Pages: 124-130
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-19590083
[Journal Article] Effects of Kupffer cell-depletion on Concanavalin A-induced hepatitis2008
- Author(s)
  Hatano, M., Sasaki, S., Ohata, S., Shiratsuchi, Y., Yamazaki, Y., Nagata, K., and Kobayashi, Y
- Journal Title
  
  Cellular Immunol 251
  
  Pages: 25-30
- Data Source
  KAKENHI-PROJECT-19590083
[Journal Article] Transient infiltration of neutrophils into the thymus following whole-body X-ray irradiation in IL-10 knockout mice2008
- Author(s)
  Fujiwara, H., Yamazaki, T., Uzawa, A., Nagata, K., and Kobayashi, Y
- Journal Title
  
  Biochem. Biophys. Res.Commun 369
  
  Pages: 432-436
- Data Source
  KAKENHI-PROJECT-19590083
[Journal Article] Neutrophils and monocytes transport tumor cell antigens from the peritoneal cavity to secondary lymphoid tissues.2008
- Author(s)
  Terasawa, M., Nagata, K., Kobayashi, Y.
- Journal Title
  
  Biochem. Biophys. Res. Commun 377
  
  Pages: 589-594
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-19590083
[Journal Article] Transient infiltration of neutrophils into the thymus following whole-body X-ray irradiation in IL-10 knockout mice.2008
- Author(s)
  Fuiiwara, H., Yamazaki, T., Uzawa, A., Nagata. K., Kobayashi, Y.
- Journal Title
  
  Biochem. Biophys. Res. Commun. . 369
  
  Pages: 432-436
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-19590083
[Journal Article] Cytokine production by M-CSF- and GM-CSF-induced mouse bone marrow-derived macrophages upon coculturing with late apoptotic cells2008
- Author(s)
  Yamazaki, T., Nagata, K., and Kobayashi, Y
- Journal Title
  
  Cellular Immunol 251
  
  Pages: 124-130
- Data Source
  KAKENHI-PROJECT-19590083
[Journal Article] Discrimination of early and late apoptotic cells by MDB-phosphat idylserine-labelling and time-lapse observation of phagocytosis of apoptotic cells by macrophages.2007
- Author(s)
  Saijo, S., Nagata, K., Masuda, J., Matsumoto, I., and Kobayashi, Y.
- Journal Title
  
  J. Biochem. 141
  
  Pages: 301-307
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-19590083
[Journal Article] Cutting Edge; A critical role of nitrogen oxide in preventing infl ammation upon apoptotic cell clearance.2007
- Author(s)
  Shibata, T., Nagata, K., and Kobayashi, Y.
- Journal Title
  
  J. Immunol. 179
  
  Pages: 3402-3406
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-19590083
[Journal Article] Cutting Edge ; A critical role of nitrogen oxide in preventing inflammation upon apoptotic cell clearance2007
- Author(s)
  Shibata, T., Nagata, K., and Kobayashi, Y
- Journal Title
  
  J. Immunol 179
  
  Pages: 3402-3406
- Data Source
  KAKENHI-PROJECT-19590083
[Journal Article] Involvement of KC, MIP-2, and MCP-1 in leukocyte infiltration following injection of necrotic cells into the peritoneal cavity2007
- Author(s)
  Tanimoto, N., Terasawa, M., Nakamura, M., Kegai, D., Aoshima, N., Kobayashi Y., and Nagata, K
- Journal Title
  
  Biochem. Biophys. Res.Commun 361
  
  Pages: 533-536
- Data Source
  KAKENHI-PROJECT-19590083
[Journal Article] Discrimination of early and late apoptotic cells by MDB-phosphatidylserine-labelling and time-lapse observation of phagocytosis of apoptotic cells by macrophages2007
- Author(s)
  Saijo, S., Nagata, K., Masuda, J., Matsumoto, I., and Kobayashi, Y
- Journal Title
  
  J. Biochem 141
  
  Pages: 301-307
- Data Source
  KAKENHI-PROJECT-19590083
[Journal Article] Infiltrating neutrophils induce allospecific CTL in response to immunization with apoptotic cells via MCP-1 production2007
- Author(s)
  Shiratsuchi, Y., Iyoda, T., Tanimoto, N., Kegai D., Nagata, K., and Kobayashi, Y
- Journal Title
  
  J. Leukoc. Biol 81
  
  Pages: 412-420
- Data Source
  KAKENHI-PROJECT-19590083
[Journal Article] Infiltrating neutrophils induce allospecific CTL in response to immunization with apoptotic cells via MCP-1 production.2007
- Author(s)
  Shiratsuchi, Y., lyoda, T., Tanimoto, N. Kegai D., Nagata. K., and Kobayashi, Y.
- Journal Title
  
  J. Leukoc. Biol. 81
  
  Pages: 412-420
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-19590083
[Journal Article] Involvement of KC, MIP-2, and MCP-1 in leukocyte infiltration following injection of necrotic cells into the peritoneal cavlty.2007
- Author(s)
  Tanimoto, N., Terasawa, M., Nakamura, M., Kegai, D., Aoshima, N., Kobayashi Y., and Nagata. K.
- Journal Title
  
  Biochem. Biophys. Res. Commun. 361
  
  Pages: 533-536
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-19590083
[Journal Article] Annexins I and IV inhibit Staphylococcus aureus attachment to human macrophages.2005
- Author(s)
  Gotoh M., Takamoto Y., Kurosaka K., Masuda J., Ida M., Satoh A., Takayama E., Kojima-Aikawa K., Kobayashi Y., Matsumoto I.
- Journal Title
  
  Immunology Letters 98
  
  Pages: 297-302
- Description
  「研究成果報告書概要(欧文)」より
- Data Source
  KAKENHI-PROJECT-16590068
[Journal Article] Neutrophils accelerate macrophage-mediated digestion of apoptotic cells in vivo as well as in vitro.2005
- Author(s)
  Iyoda, T., Nagata, K., Akashi, M., Kobayashi, Y.
- Journal Title
  
  J.Immunol. 175
  
  Pages: 3475-3483
- Description
  「研究成果報告書概要(欧文)」より
- Data Source
  KAKENHI-PROJECT-16590068
[Journal Article] Inhibition by adiponectin of IL-8 production by human macrophages upon coculturing with late apoptotic cells.2005
- Author(s)
  Saijo, S., Nagata, K., Nakano, Y., Tobe, T., Kobayashi, Y.
- Journal Title
  
  Biochem Biophys Res Commun 334
  
  Pages: 1180-1183
- Description
  「研究成果報告書概要(欧文)」より
- Data Source
  KAKENHI-PROJECT-16590068
[Journal Article] A novel accessory role of neutrophils in Concanavalin A-induced hepatitis.2005
- Author(s)
  Hatada, S., Ohta, T.Shiratsuchi, Y., Hatano, M., Kobayashi, Y.
- Journal Title
  
  Cell.Immunol. 233
  
  Pages: 23-29
- Description
  「研究成果報告書概要(欧文)」より
- Data Source
  KAKENHI-PROJECT-16590068
[Journal Article] Involvement of MIP-2 and CXCR2 in neutrophil infiltration following injection of late apoptotic cells into the peritoneal cavity2004
- Author(s)
  Iyoda T., Kobayashi Y
- Journal Title
  
  Apoptosis 9
  
  Pages: 485-493
- Data Source
  KAKENHI-PROJECT-16590068
[Journal Article] Gene expression in the elicitation phase of guinea pig DTH and CHS reactions.2004
- Author(s)
  Ohtani, M., Kobayashi, Y., Watanabe, N.
- Journal Title
  
  Cytokine 25
  
  Pages: 246-253
- Description
  「研究成果報告書概要(欧文)」より
- Data Source
  KAKENHI-PROJECT-16590068
[Journal Article] Immature dendritic cells reduce proinflammatory cytokine production by a coculture of macrophages and apoptotic cells in a cell-cell contact-dependent manner.2004
- Author(s)
  Takahashi M., Kurosaka K., Kobayashi, Y.
- Journal Title
  
  J.Leukoc.Biol. 75
  
  Pages: 865-873
- Description
  「研究成果報告書概要(欧文)」より
- Data Source
  KAKENHI-PROJECT-16590068
[Presentation] ネクローシス細胞により誘発される炎症応答の終息と好酸球の関わり2017
- Author(s)
  懸川奈央、佐藤麻実、石神昭人、小林芳郎、永田喜三郎
- Organizer
  生命科学系学会合同年次大会　（第40回日本分子生物学会集会）
- Data Source
  KAKENHI-PROJECT-15K07949
[Presentation] 腹腔常在性マクロファージの貪食応答に対する環境エンリッチメントの効果2017
- Author(s)
  大滝桃子、小鹿成二、西村まゆみ、柿沼志津子、島田義也、小林芳郎、永田喜三郎
- Organizer
  生命科学系学会合同年次大会　（第40回日本分子生物学会集会）
- Data Source
  KAKENHI-PROJECT-15K07949
[Presentation] The mechanism for β-glucan-mediated inhibition of phagocytosis of apoptotic cells by macrophages.2015
- Author(s)
  平野哲也、永田喜三郎、小林芳郎
- Organizer
  第44回日本免疫学会
- Place of Presentation
  札幌コンベンションセンター　（北海道札幌市）
- Year and Date
  2015-11-19
- Data Source
  KAKENHI-PROJECT-15K07949
[Presentation] Neutrophil infiltration is essential for gastric mucosal injury in mice with water-immersion stress.2015
- Author(s)
  近藤嘉高、永田喜三郎、小林芳郎
- Organizer
  第44回日本免疫学会
- Place of Presentation
  札幌コンベンションセンター　（北海道札幌市）
- Year and Date
  2015-11-18
- Data Source
  KAKENHI-PROJECT-15K07949
[Presentation] The role of S100 A8 and A9 proteins in inflammatory responses induced by necrotic cells.2015
- Author(s)
  市原理恵、小林芳郎、永田喜三郎
- Organizer
  第44回日本免疫学会
- Place of Presentation
  札幌コンベンションセンター　（北海道札幌市）
- Year and Date
  2015-11-20
- Data Source
  KAKENHI-PROJECT-15K07949
[Presentation] The phagocytic capacity of macrophages in aged mice was reduced.2014
- Author(s)
  1高橋澪、小林芳郎、永田喜三郎
- Organizer
  第43回日本免疫学会
- Place of Presentation
  国立京都国際会館（京都府京都市）
- Year and Date
  2014-12-11
- Data Source
  KAKENHI-PROJECT-24590100
[Presentation] The relation between neutrophil infiltration and ischemia in stress-induced gastric injury in mice.2014
- Author(s)
  滝野有花、永田喜三郎、小林芳郎
- Organizer
  第43回日本免疫学会
- Place of Presentation
  国立京都国際会館（京都府京都市）
- Year and Date
  2014-12-11
- Data Source
  KAKENHI-PROJECT-24590100
[Presentation] The mechanism for β-glucan-mediated inhibition of phagocytosis of apoptotic cells by macrophages.2014
- Author(s)
  関口朱津乃、永田喜三郎、小林芳郎
- Organizer
  第43回日本免疫学会
- Place of Presentation
  国立京都国際会館（京都府京都市）
- Year and Date
  2014-12-11
- Data Source
  KAKENHI-PROJECT-24590100
[Presentation] 老化促進モデルマウス(SMP30/GNL-/-)におけるアポトーシス細胞の貪食除去応答2011
- Author(s)
  高橋澪、石神昭人、小林芳郎、永田喜三郎
- Organizer
  第12回Pharmaco-Hematology Symposium
- Place of Presentation
  富山
- Data Source
  KAKENHI-PROJECT-21590078
[Presentation] Effect of aging on inflammatory responses to necrotic cells2011
- Author(s)
  山口正昭、小林芳郎、永田喜三郎
- Organizer
  第40回日本免疫学会学術集会
- Place of Presentation
  千葉
- Data Source
  KAKENHI-PROJECT-21590078
[Presentation] Identification of S100A9 protein producing cell in inflammatory responses induced by necrotic neutrophils2011
- Author(s)
  玉置豊、小林芳郎、永田喜三郎
- Organizer
  第40回日本免疫学会学術集会
- Place of Presentation
  千葉
- Data Source
  KAKENHI-PROJECT-21590078
[Presentation] Effect of aging on inflammatory responses to apoptotic cells2011
- Author(s)
  高橋澪、小林芳郎、永田喜三郎
- Organizer
  第40回日本免疫学会学術集会
- Place of Presentation
  千葉
- Data Source
  KAKENHI-PROJECT-21590078
[Presentation] Regulation of phagocytic responses of macrophages by soluble and particulate β-glucan2011
- Author(s)
  富沢由、永田喜三郎、小林芳郎
- Organizer
  第40回日本免疫学会学術集会
- Place of Presentation
  千葉
- Data Source
  KAKENHI-PROJECT-21590078
[Presentation] The role of Annexins I and IV in macrophage response to apoptotic cells.2010
- Author(s)
  Iwasa, T., Nagata, K., Kobayashi Y.
- Organizer
  14^<th> International Congress of immunology.
- Place of Presentation
  神戸国際展示場(兵庫県)
- Data Source
  KAKENHI-PROJECT-21590078
[Presentation] Effect of aging on inflammatory responses to dead cells. 14^<th> International Congress of immunology.2010
- Author(s)
  Nagata, K., Takahashi, R., Yamaguchi, M., Totsuka S., Ishigami, A., Kobayashi Y.
- Organizer
  14^<th> International Congress of immunology.
- Place of Presentation
  神戸ポートピアホテル(兵庫県)
- Data Source
  KAKENHI-PROJECT-21590078
[Presentation] The role of Annexins I and IV in macrophage response to apoptotic cells2010
- Author(s)
  Iwasa, T., Nagata, K., and Kobayashi Y.
- Organizer
  14^<th> International Congress of immunology
- Place of Presentation
  Kobe, Japan
- Data Source
  KAKENHI-PROJECT-21590078
[Presentation] Effect of aging on inflammatory responses to dead cells2010
- Author(s)
  Nagata, K., Takahashi, R., Yamaguchi, M., Totsuka S., Ishigami, A., and Kobayashi Y.
- Organizer
  14^<th> International Congress of immunology
- Place of Presentation
  Kobe, Japan
- Data Source
  KAKENHI-PROJECT-21590078
[Presentation] The role of annexins I and IV in macrophage response to apoptotic cells2010
- Author(s)
  岩佐卓哉、永田喜三郎、小林芳郎
- Organizer
  第14回国際免疫学会
- Place of Presentation
  神戸
- Year and Date
  2010-08-25
- Data Source
  KAKENHI-PROJECT-21590077
[Presentation] Regulation of the estrous cycle by opioid peptides from neutrophils infiltrated into female genital organ2009
- Author(s)
  Sohichiro S., Nagata, K., and Kobayashi Y.
- Organizer
  The 9^<th> world congress on inflammation
- Place of Presentation
  Tokyo, Japan
- Data Source
  KAKENHI-PROJECT-21590078
[Presentation] Regulation of the estrous cycle by opioid peptides from neut rophils infiltrated into female genital organ2009
- Author(s)
  Sohichiro S., Nagata, K., Kobayashi Y.
- Organizer
  The 9^<th> world congress on inflammation
- Place of Presentation
  東京
- Data Source
  KAKENHI-PROJECT-21590078
[Presentation] 炎症の終息における一酸化窒素の役割2009
- Author(s)
  柴田岳彦、永田喜三郎、小林芳郎
- Organizer
  第39回日本免疫学会学術集会
- Place of Presentation
  大阪
- Data Source
  KAKENHI-PROJECT-21590078
[Presentation] 炎症の終息における一酸化窒素の役割2009
- Author(s)
  柴田岳彦、永田喜三郎、小林芳郎
- Organizer
  第39回日本免疫学会
- Place of Presentation
  大阪
- Year and Date
  2009-12-04
- Data Source
  KAKENHI-PROJECT-21590077
[Presentation] アポトーシス細胞の食食における Annexin I,IVの役割2009
- Author(s)
  岩佐卓哉, 永田喜三郎, 小林芳郎
- Organizer
  第39回日本免疫学会学術集会
- Place of Presentation
  大阪
- Data Source
  KAKENHI-PROJECT-21590078
[Presentation] A critical role of nitric oxide in the resolution of inflammation2009
- Author(s)
  Kobayashi Y., Shibata T., Nagata, K.
- Organizer
  Tri-Society Annual Conference 2009 of the Society for Leukocyte Biology, International Cytokine Society, & International Society for Interferon and Cytokine Research
- Place of Presentation
  Lisbon, Portugal
- Data Source
  KAKENHI-PROJECT-21590078
[Presentation] 接触過敏症における好中球浸潤に対するIL-10の役割2009
- Author(s)
  山田真里亜、永田喜三郎、小林芳郎
- Organizer
  第39回日本免疫学会学術集会
- Place of Presentation
  大阪
- Data Source
  KAKENHI-PROJECT-21590078
[Presentation] アポトーシス細胞の貪食におけるAnnexin I, IVの役割2009
- Author(s)
  岩佐卓哉、永田喜三郎、小林芳郎
- Organizer
  第39回日本免疫学会学術集会
- Place of Presentation
  大阪
- Data Source
  KAKENHI-PROJECT-21590078
[Presentation] Necrotic cell type-dependent induction of inflammatory response2009
- Author(s)
  Nagata, K., Miho, N., Kobayashi Y.
- Organizer
  The 6^<th> Joint Seminar on Biomedical Sciences
- Place of Presentation
  東京
- Data Source
  KAKENHI-PROJECT-21590078
[Presentation] Necrotic cell type-dependent induction of inflammatory response2009
- Author(s)
  Nagata, K., Miho, N., and Kobayashi Y.
- Organizer
  The 6^<th> Joint Seminar on Biomedical Sciences
- Place of Presentation
  Tokyo, Japan
- Data Source
  KAKENHI-PROJECT-21590078
[Presentation] A critical role of nitric oxide in the resolution of inflammation. Tri-Society Annual Conference 2009 of the Society for Leukocyte Biology2009
- Author(s)
  Kobayashi Y., Shibata T., and Nagata, K.
- Organizer
  International Cytokine Society, & International Society for Interferon and Cytokine Research
- Place of Presentation
  Lisbon, Portugal
- Data Source
  KAKENHI-PROJECT-21590078
[Presentation] ネクローシス細胞に対する生体の応答2008
- Author(s)
  中村美保、永田喜三郎、小林芳郎
- Organizer
  第38回日本免疫学会学術集会
- Place of Presentation
  京都
- Data Source
  KAKENHI-PROJECT-19590083
[Presentation] 未熟樹状細胞のアポトーシス細胞貪食時における好中球の役割2008
- Author(s)
  金野なつみ、永田喜三郎、小林芳郎
- Organizer
  第38回日本免疫学会学術集会
- Place of Presentation
  京都
- Data Source
  KAKENHI-PROJECT-19590083
[Presentation] マクロファージによるアポトーシス細胞の貪食における消化の意義2008
- Author(s)
  坪井久美子、永田喜三郎、小林芳郎
- Organizer
  第38回日本免疫学会学術集会
- Place of Presentation
  京都
- Data Source
  KAKENHI-PROJECT-19590083
[Presentation] 接触過敏症における浸潤好中球の役割2008
- Author(s)
  山崎貴裕、永田喜三郎、小林芳郎
- Organizer
  第38回日本免疫学会学術集会
- Place of Presentation
  京都
- Data Source
  KAKENHI-PROJECT-19590083
[Presentation] 死細胞に対する生体の応答-アポトーシスからネクローシスまで-2008
- Author(s)
  永田喜三郎、中村美保、小林芳郎
- Organizer
  第17回日本アポトーシス研究会学術集会
- Place of Presentation
  京都
- Data Source
  KAKENHI-PROJECT-19590083
[Presentation] 好中球によるオピオイドペプチド産生を介した性周期の維持2008
- Author(s)
  佐々木宗一郎、永田喜三郎、小林芳郎
- Organizer
  第38回日本免疫学会学術集会
- Place of Presentation
  京都
- Data Source
  KAKENHI-PROJECT-19590083
[Presentation] 好中球のアポトーシスを伴う炎症の終息における一酸化窒素の役割2008
- Author(s)
  柴田岳彦、永田喜三郎、小林芳郎
- Organizer
  第38回日本免疫学会学術集会
- Place of Presentation
  京都
- Data Source
  KAKENHI-PROJECT-19590083
[Presentation] Caspase活性を指標としたアポトーシス進行段階の解析およびマクロファージによる極初期アポトーシス細胞の認識機構の解析2007
- Author(s)
  高木秀幸、永田喜三郎、小林芳郎
- Organizer
  第16回日本アポトーシス研究会学術集会
- Place of Presentation
  千葉
- Data Source
  KAKENHI-PROJECT-19590083
[Presentation] アポトーシス細胞とネクローシス細胞の腹腔投与によって浸潤する好中球の特徴2007
- Author(s)
  武富絢子、永田喜三郎、小林芳郎
- Organizer
  第37回日本免疫学会学術集会
- Place of Presentation
  東京
- Data Source
  KAKENHI-PROJECT-19590083
[Presentation] 極初期アポトーシス細胞のマクロファージによる認識2007
- Author(s)
  高木秀幸、永田喜三郎、小林芳郎
- Organizer
  第37回日本免疫学会学術集会
- Place of Presentation
  東京
- Data Source
  KAKENHI-PROJECT-19590083
[Presentation] The physiological significance of an estrus cycle-dependent infiltration of leukocyte into female genital organ.2007
- Author(s)
  Sasaki, S., Nagata, K., and Kobayashi Y.
- Organizer
  The 16th International Symposium on Molecular Cell Biology of macrophages.
- Place of Presentation
  Shizuoka, JPN
- Data Source
  KAKENHI-PROJECT-19590083
[Presentation] 雌マウス生殖器官に一過的に浸潤する白血球の生理的意義2007
- Author(s)
  佐々木宗一郎、永田喜三郎、小林芳郎
- Organizer
  第37回日本免疫学会学術集会
- Place of Presentation
  東京
- Data Source
  KAKENHI-PROJECT-19590083
[Presentation] 肺胞マクロファージによるアポトーシス細胞の貪食応答と肺胞内環境によるその制御2007
- Author(s)
  丹羽広之、松浦隆之、永田喜三郎、小林芳郎
- Organizer
  第37回日本免疫学会学術集会
- Place of Presentation
  東京
- Data Source
  KAKENHI-PROJECT-19590083
[Presentation] ネクローシス細胞に対する生体の応答2007
- Author(s)
  中村美保、谷本奈緒子、寺沢公男、白土佳子、永田喜三郎、小林芳郎
- Organizer
  第37回日本免疫学会学術集会
- Place of Presentation
  東京
- Data Source
  KAKENHI-PROJECT-19590083
[Presentation] A critical role of nitric oxide in silent cleanup of early apoptotic cells.2007
- Author(s)
  Kobayashi Y., Shibata T., and Nagata, K.
- Organizer
  Gordon Research Conferences(Apoptotic Cell Recognition & Clearance).
- Place of Presentation
  Lewiston, ME, USA
- Data Source
  KAKENHI-PROJECT-19590083
[Presentation] 貪食巣浸潤における好中球の活性化機構および活性化好中球の役割の解明2007
- Author(s)
  金野なつみ、永田喜三郎、小林芳郎
- Organizer
  第37回日本免疫学会学術集会
- Place of Presentation
  東京
- Data Source
  KAKENHI-PROJECT-19590083
[Presentation] 接触過敏症における浸潤好中球の役割2007
- Author(s)
  山崎貴裕、永田喜三郎、小林芳郎
- Organizer
  第37回日本免疫学会学術集会
- Place of Presentation
  東京
- Data Source
  KAKENHI-PROJECT-19590083
[Presentation] アポトーシス細胞の処理に伴う一酸化窒素の炎症応答抑制作用2007
- Author(s)
  柴田岳彦、永田喜三郎、小林芳郎
- Organizer
  第37回日本免疫学会学術集会
- Place of Presentation
  東京
- Data Source
  KAKENHI-PROJECT-19590083
[Presentation] 腫瘍細胞特異的キラーT細胞誘導における2次リンパ組織への腫瘍抗原移動機構2007
- Author(s)
  寺沢公男、永田喜三郎、小林芳郎
- Organizer
  第37回日本免疫学会学術集会
- Place of Presentation
  東京
- Data Source
  KAKENHI-PROJECT-19590083
[Presentation] マクロファージのアポトーシス細胞貪食応答における消化の意義2007
- Author(s)
  坪井久美子、永田喜三郎、小林芳郎
- Organizer
  第16回日本アポトーシス研究会学術集会
- Place of Presentation
  千葉
- Data Source
  KAKENHI-PROJECT-19590083
[Presentation] The role of S100A9 protein in the late stage of inflammatory response induced necrotic cells.
- Author(s)
  與座法子、小林芳郎、永田喜三郎
- Organizer
  第41回日本免疫学会学術集会
- Place of Presentation
  神戸国際会議場、神戸国際展示場、神戸ポートピアホテル（兵庫県）
- Data Source
  KAKENHI-PROJECT-24590100
[Presentation] Macrophage in aged mice are pre-activated.
- Author(s)
  高橋澪、小林芳郎、永田喜三郎
- Organizer
  第41回日本免疫学会学術集会
- Place of Presentation
  神戸国際会議場、神戸国際展示場、神戸ポートピアホテル（兵庫県）
- Data Source
  KAKENHI-PROJECT-24590100
[Presentation] Effect of aging on inflammatory responsens to apoptotic cells
- Author(s)
  高橋澪、小林芳郎、永田喜三郎
- Organizer
  第42回日本免疫学会学術集会
- Place of Presentation
  幕張メッセ（千葉県）
- Data Source
  KAKENHI-PROJECT-24590100

1. NAGATA Kisaburo (10291155)

# of Collaborated Projects: 5 results

# of Collaborated Products: 87 results
2. WATANABE Naoko (80230978)

# of Collaborated Projects: 5 results

# of Collaborated Products: 0 results
3. IWAMURA Michiko (90057597)

# of Collaborated Projects: 2 results

# of Collaborated Products: 0 results
4. MATSUSHIMA Kouji (50222427)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
5. HARADA Akihisa (00228636)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
6. KASAHARA Tadashi (60049096)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
7. MUKAIDA Naofumi (30182067)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
8. WATANABE Soichiro (10287550)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
9. OSAWA Toshiaki (40012603)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
10. 長島誠 (80349901)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
11. OPPENHEIM Joost.J.

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
12. THESTRUPーPED クリスチ

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
13. PEDERSEN Kri

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
14. 石神昭人

# of Collaborated Projects: 0 results

# of Collaborated Products: 2 results

KOBAYASHI Yoshiro 小林 芳郎

KOBAYASHI YOSHIRO 小林 芳郎

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Resolution of inflammation through macrophage response to apoptotic neutrophilsPrincipal Investigator

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Responses in a coculture of macrophages, immature dendritic cells and apoptotic cellsPrincipal Investigator

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In vivo role of the responce of macrophages after phagocytosis of appptotic cellsPrincipal Investigator

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Pathological Significance of the response of macrophages after phagocytosis of apoptotic cellsPrincipal Investigator

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Regulatory Mechanism of Processing and Release of IL-lalphaPrincipal Investigator

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KOBAYASHI Yoshiro 小林芳郎

KOBAYASHI YOSHIRO 小林芳郎