AKIMOTO Yoshiaki 秋元芳明

… Alternative Names

秋本芳明アキモトヨシアキ

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Researcher Number	10147720
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External Links
Affiliation (based on the past Project Information) *help	2013: 日本大学, 松戸歯学部, 教授 2011 – 2013: 日本大学, 歯学部, 教授 2003 – 2009: Nihon University, School of Dentistry at Matsudo, Professor, 松戸歯学部, 教授 1997 – 2002: 日本大学, 松戸歯学部, 助教授 1999: 日本学部, 松戸歯学部, 助教授 1994 – 1995: 日本大学, 松戸歯学部, 助教授 1990 – 1993: 日本大学, 松戸歯学部, 専任講師
Review Section/Research Field	Principal Investigator Surgical dentistry / Surgical dentistry / 外科・放射線系歯学 Except Principal Investigator 病態科学系歯学(含放射線系歯学) / Pathobiological dentistry/Dental radiology / Functional basic dentistry / 畜産化学
Keywords	Principal Investigator 分離頻度 / antimicrobial susceptibility / メチシリン耐性黄色ブドウ球菌 / 皮下膿瘍 / 歯性感染症 / Staphylococcus aureus / 感受性 / 黄色ブドウ球菌 / methicillin-resistant Staphylococcus aureus / メチシリン耐性ブドウ球菌 … More / incidence of isolation / odontogenic infection / Staphylococcus epidermidis / 抗菌薬感受性 / 白色ブドウ球菌 / 薬剤感受性 / subcutanus abscess / methicillin-resistant Staphylococcus epidermidis / methicillin-resistant staphylococci / メチシリン耐性白色ブドウ球菌 / Antimicrobial susceptibility / Incidence of isolation / Odontogenic infection / Methicillin-resistant staphylococci / メシシリン耐性白色ブドウ球菌 / subcutaneous abscess / methicillin-resistant coagulase negative staphylococci / コアグラーゼ陰性メチシリン耐性ブドウ球菌 / メチシリン耐性コアグラーゼ陰性ブドウ球菌 / odontogenic and oral infections / incidence / 歯性・口腔感染症 / oral infection / Bーlactamaseの産生能 / MRSA / 口腔感染症 … More Except Principal Investigator Nifedipine / カルシウム拮抗薬 / 歯肉線維芽細胞 / ニフェジピン / IL-1α / 歯肉肥厚 / Human Gingival Fibroblast / bFGF / 細胞増殖 / HO-1-N-1 cell / PMA / IL-1β / ESE / NSAID / 歯肉培養線維芽細胞 / 歯肉増殖症 / BMC / BMD / pQCT / 細胞内pH / Gingival Overgrowth / Intracellular Signaling / 蛋白リン酸化 / 細胞内情報伝達 / ブラジキニン / 転写因子 / 細胞周期 / transcription factor / buccal mucosa carcinoma-derived cell / ESE-3 / HO-1-N-1細胞 / 口腔扁平上皮癌由来上皮様細胞 / HO-1-N-1 / gingival overgrowth / cyclin-dependent kinase (CDK) / cyclin / cell growth / cell cycle / gingival fibroblast / nifedipine / p38MAPK / 歯肉増殖 / サイクリン依存性キナーゼ / サイクリン / [Ca^<2+>]i / pHi / protein phosphorylation / Calcium Channel Blocker / 細胞内Ca濃度 / Trabecular bone / Femur / Rat / Mandible / Osteoporosis / 海綿骨 / 下顎骨 / 大腿骨 / ラット / 実験的骨粗鬆症 / Rats and Dogs / Experimental Gingival Overgrowth / ジクロフェナクナトリウム / メフェナム酸 / インドメタシン / テニダップ / 合成抗炎症薬 / 細胞内カルシウム / 歯肉肥厚の治療 / NIFEDIPINE / TENIDAP / Calcium Channel Blockers / リン酸化蛋白質 / cAMP / ヒト歯肉線維芽細胞 / Bradykinin / Intracellular calcium resoinse / Tissue culture / Gingival fibroblasts / Gingival hyperplasia / 細胞内カルシウム濃度 / カルシウム取り込み / コラーゲン合成能 / 線維芽細胞 / カルシウム拮抗剤 / ヒスタミン / フェニトン / DNA合成能 / 細胞内カルシウム応答 / 組織培養 / 炎症性因子 / ets遺伝子 / 薬物性歯肉肥厚 / Ets遺伝子 / フェニトイン / ets-1 / 脂肪抑制像 / T2強調像 / T1強調像 / 被曝のない骨梁解析 / 顎骨の質的評価 / 骨梁の描出 / MRIマイクロスコピーコイル / 磁気共鳴画像検査 / MIC / 血清濃度 / 歯根肉芽腫濃度 / 連続経口投与 / 1回経口投与 / メロフロキサシン Less

Mechanism of gingival overgrowth caused by medication - Expression and role of ets transcription factor -
- Principal Investigator
  
  MATSUMOTO Hiroko
- Project Period (FY)
  2011 – 2013
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Research Field
  
  Pathobiological dentistry/Dental radiology
- Research Institution
  Nihon University
Assessment of bone quality of the jaw using MRI microscopy coil
- Principal Investigator
  
  KANEDA Takashi
- Project Period (FY)
  2007 – 2009
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Research Field
  
  Pathobiological dentistry/Dental radiology
- Research Institution
  Nihon University
Ets family expression in cultured cells from oral tissue
- Principal Investigator
  
  MATSUMOTO Hiroko
- Project Period (FY)
  2004 – 2006
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Research Field
  
  Pathobiological dentistry/Dental radiology
- Research Institution
  Nihon University
Methicillin-resistant staphylococci isolated from odontogenic infectionPrincipal Investigator
- Principal Investigator
  
  AKIMOTO Yoshiaki
- Project Period (FY)
  2004 – 2006
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Research Field
  
  Surgical dentistry
- Research Institution
  Nihon University
Cell Growth and Cell Cycle in Nifedipine-Reactive Human Gingival Fibroblasts
- Principal Investigator
  
  FUJII Akira, 松本裕子
- Project Period (FY)
  2001 – 2003
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Research Field
  
  病態科学系歯学(含放射線系歯学)
- Research Institution
  Nihon University
Clinical and Bacteriological study of methicillin-resistant staphylococci isolated from odontogenic infection.Principal Investigator
- Principal Investigator
  
  AKIMOTO Yoshiaki
- Project Period (FY)
  2001 – 2003
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Research Field
  
  Surgical dentistry
- Research Institution
  Nihon University
Mandible Bone Change in Osteoporosis Rats and Therapeutic Treatment
- Principal Investigator
  
  AKIRA Fujii
- Project Period (FY)
  1999 – 2000
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Research Field
  
  病態科学系歯学(含放射線系歯学)
- Research Institution
  Nihon University
Clarification of Intracellular Signal Transductions in Nifedipine-Reactive Human Gingival Fibroblasts
- Principal Investigator
  
  MATSUMOTO Hiroko
- Project Period (FY)
  1999 – 2000
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Research Field
  
  病態科学系歯学(含放射線系歯学)
- Research Institution
  Nihon University
TREATMENT OF GINGIVAL OVERGROWTH CAUSED BY MEDICATION
- Principal Investigator
  
  FUJII Akira
- Project Period (FY)
  1998 – 1999
- Research Category
  
  Grant-in-Aid for Scientific Research (B)
- Research Field
  
  病態科学系歯学(含放射線系歯学)
- Research Institution
  Nihon University
EFFECT OF NIFEDIPINE ON INTRACELLULAR SIGNAL TRANSDUCTIONS IN HUMAN GINGIVAL FIBROBLASTS
- Principal Investigator
  
  FUJII Akira
- Project Period (FY)
  1997 – 1998
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Research Field
  
  Functional basic dentistry
- Research Institution
  Nihon University
Incidence of isolation and antimicrobial susceptibility of methicillin-resistant coagulase negative staphylococci isolated from odontogenic infectionPrincipal Investigator
- Principal Investigator
  
  AKIMOTO Yoshiaki
- Project Period (FY)
  1997 – 1998
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Research Field
  
  Surgical dentistry
- Research Institution
  Nihon University
Incidence of isolation and antimicrobialPrincipal Investigator
- Principal Investigator
  
  AKIMOTO Yoshiaki
- Project Period (FY)
  1994 – 1995
- Research Category
  
  Grant-in-Aid for General Scientific Research (C)
- Research Field
  
  Surgical dentistry
- Research Institution
  Nihon University
ロメフロキサシン経口投与後の歯根肉芽腫への移行について
- Principal Investigator
  
  金子賢司
- Project Period (FY)
  1993
- Research Category
  
  Grant-in-Aid for General Scientific Research (C)
- Research Field
  
  病態科学系歯学(含放射線系歯学)
- Research Institution
  Nihon University
Influence (Gingival Hyperplasia) of Nifedipine in Oral Region
- Principal Investigator
  
  FUJII Akira
- Project Period (FY)
  1992 – 1993
- Research Category
  
  Grant-in-Aid for General Scientific Research (C)
- Research Field
  
  畜産化学
- Research Institution
  Nihon University
Antimicrobial susceptibilities of methicillin-resistant Staphylococcus aureus isolated from oral infectionPrincipal Investigator
- Principal Investigator
  
  AKIMOTO Yoshiaki
- Project Period (FY)
  1990 – 1992
- Research Category
  
  Grant-in-Aid for General Scientific Research (C)
- Research Field
  
  外科・放射線系歯学
- Research Institution
  Nihon University

All 2014 2013 2012 2011

All Journal Article Presentation

[Journal Article] The Inhibitory Action of Amlodipine for TNF-α-induced Apoptosis in Cultured Human Gingival Fibroblasts2012
- Author(s)
  Reiri Takeuchi，Hiroko Matsumoto， Yoshiaki Akimoto，Akira Fujii
- Journal Title
  
  Oral Therap Pharmacol
  
  Volume: 31(2) Pages: 45-52
- NAID
  10031168920
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-23592779
[Journal Article] Inhibition of G1 Cell Cycle Arrest in Human Gingival Fibroblasts Exposed to Phenytoin2012
- Author(s)
  Reiri Takeuchi，Hiroko Matsumoto， Yoshiaki Akimoto，Akira Fujii
- Journal Title
  
  Fundam Clin Pharmacol
  
  Volume: 2012 Issue: 1 Pages: 1-6
- DOI
  10.1111/j.1472-8206.2012.01065.x
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-23592779
[Journal Article] The Inhibitory, Action of Amlodipine for TNF-α-induced Apopto- sis in Cultured Human Gingival Fibro- blasts2012
- Author(s)
  Takeuchi R,Matsumoto H,Akimoto Y,Fujii A
- Journal Title
  
  歯科薬物療法
  
  Volume: 31(2) Pages: 45-52
- NAID
  10031168920
- URL
  https://www.jstage.jst.go.jp/browse/jsotp/31/2/_contents/-char/ja
- Data Source
  KAKENHI-PROJECT-23592779
[Presentation] Effect of phenytoin on caspase activity in cultured human gingival fibroblasts2014
- Author(s)
  Reiri Takeuchi, Makiko Ono, Yoshiaki Akimoto, Akira Fujii, Hiroko Matsumoto
- Organizer
  第34回日本歯科薬物療法学会
- Place of Presentation
  大阪歯科大学創立100周年記念館（大阪）
- Data Source
  KAKENHI-PROJECT-23592779
[Presentation] 18-alpha- glycyrrhetinic acid suppresses G1/S- phase transition and induces apoptosis in gingival fibroblast isolated from a patient that presented with nifedi- pine-induced gingival overgrowth2014
- Author(s)
  Takeuchi R, Ono M, Arikawa K, Akimoto Y, Fujii A, Matsumoto H
- Organizer
  17th World Congress on Basic & Clinical Pharmacology
- Place of Presentation
  Cape Town International Convention Center (Cape Town)
- Year and Date
  2014-07-13
- Data Source
  KAKENHI-PROJECT-23592779
[Presentation] 18-alpha-glycyrrhetinic acid suppresses G1/S-phase transition and induces apoptosis in gingival fibroblast isolated from a patient that presented with nifedipine-induced gingival overgrowth2014
- Author(s)
  Reiri Takeuchi, Makiko Ono, Kazumune Arikawa, Yoshiaki Akimoto, Akira Fujii, Hiroko Matsumoto
- Organizer
  17th World Congress on Basic & Clinical Pharmacology
- Place of Presentation
  Cape Town International Convention Centre (Cape Town)
- Data Source
  KAKENHI-PROJECT-23592779
[Presentation] Effect of phenytoin on caspase activity in cultured human gingival fibroblasts2014
- Author(s)
  Takeuchi R, Ono M, Akimoto Y, Fujii A, Matsumoto H
- Organizer
  第34回日本歯科薬物療法学会
- Place of Presentation
  大阪歯科大学(大阪)
- Year and Date
  2014-06-21
- Data Source
  KAKENHI-PROJECT-23592779
[Presentation] Tentative Pharmaco- therapy for Nifedipine-induced Gin- gival Overgrowth using 18α-glycyr- rhetinic Acid2013
- Author(s)
  Takeuchi R, Ono M, Akimoto Y, Fujii A, Matsumoto H
- Organizer
  第33回日本歯科薬物療法学会
- Place of Presentation
  東京医科歯科大学(東京)
- Year and Date
  2013-06-14
- Data Source
  KAKENHI-PROJECT-23592779
[Presentation] Tentative Pharmacotherapy for Nifedipine-induced Gingival Overgrowth using 18α-glycyrrhetinic Acid2013
- Author(s)
  Reiri Takeuchi, Makiko Ono, Yoshiaki Akimoto, Akira Fujii, Hiroko Matsumoto
- Organizer
  第33回日本歯科薬物療法学会
- Place of Presentation
  東京医科歯科大学（東京）
- Data Source
  KAKENHI-PROJECT-23592779
[Presentation] The Mechanism of Phenytoin-induced Gingival Overgrowth2012
- Author(s)
  Reiri Takeuchi，Hiroko Matsumoto， Yoshiaki Akimoto，Akira Fujii
- Organizer
  第32回日本歯科薬物療法学会
- Place of Presentation
  大阪国際会議場（大阪）
- Data Source
  KAKENHI-PROJECT-23592779
[Presentation] The Mechanism of Phenytoin- induced Gingival Overgrowth2011
- Author(s)
  Takeuchi R, Matsumoto H, Akimoto Y, Fujii A
- Organizer
  第32回日本歯科薬物療法学会
- Place of Presentation
  大阪国際会議場(大阪)
- Year and Date
  2011-06-30
- Data Source
  KAKENHI-PROJECT-23592779
[Presentation] The Mechanism of Nifedipine- induced Gingival Overgrowth2011
- Author(s)
  Takeuchi R, Matsumoto H, Akimoto Y, Fujii A
- Organizer
  第53回歯科基礎医学会
- Place of Presentation
  長良川国際会議場(岐阜)
- Year and Date
  2011-10-02
- Data Source
  KAKENHI-PROJECT-23592779
[Presentation] アムロジピンによる歯肉肥厚の発症機序2011
- Author(s)
  松本裕子,竹内麗理,小野眞紀子,秋元芳明,藤井彰
- Organizer
  第13回応用薬理シンポジウム
- Place of Presentation
  日本大学薬学部(船橋)
- Year and Date
  2011-09-04
- Data Source
  KAKENHI-PROJECT-23592779

1. FUJII Akira (70102564)

# of Collaborated Projects: 14 results

# of Collaborated Products: 0 results
2. MATSUMOTO Hiroko (50221594)

# of Collaborated Projects: 13 results

# of Collaborated Products: 13 results
3. YAMAMOTO Hirotsugu (00102591)

# of Collaborated Projects: 5 results

# of Collaborated Products: 0 results
4. SHIBUTANI Jun (20206147)

# of Collaborated Projects: 5 results

# of Collaborated Products: 0 results
5. ONO Makiko (00267113)

# of Collaborated Projects: 4 results

# of Collaborated Products: 0 results
6. NISHIMURA Hitoshi (10198509)

# of Collaborated Projects: 3 results

# of Collaborated Products: 0 results
7. KANEDA Takashi (40185947)

# of Collaborated Projects: 2 results

# of Collaborated Products: 0 results
8. MORI Shintaro (40419792)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
9. OKADA Hiroyuki (70256890)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
10. TAKEUCHI Reiri (60419778)

# of Collaborated Projects: 1 results

# of Collaborated Products: 13 results
11. MOCHIZUKI Yoshiko (90200336)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
12. KOMIYA Masamichi (40186812)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
13. HIRAYAMA Teruyasu (10189871)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
14. 金子賢司 (20050007)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
15. 小俣裕昭 (10241100)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
16. 加藤正隆 (40434097)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
17. 山根潤一 (20220428)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
18. 中尾寿美 (20102577)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
19. 池田眞紀子

# of Collaborated Projects: 0 results

# of Collaborated Products: 7 results

AKIMOTO Yoshiaki 秋元 芳明

秋本 芳明 アキモト ヨシアキ

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Methicillin-resistant staphylococci isolated from odontogenic infectionPrincipal Investigator

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Clinical and Bacteriological study of methicillin-resistant staphylococci isolated from odontogenic infection.Principal Investigator

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Incidence of isolation and antimicrobial susceptibility of methicillin-resistant coagulase negative staphylococci isolated from odontogenic infectionPrincipal Investigator

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Incidence of isolation and antimicrobialPrincipal Investigator

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Antimicrobial susceptibilities of methicillin-resistant Staphylococcus aureus isolated from oral infectionPrincipal Investigator

AKIMOTO Yoshiaki 秋元芳明

秋本芳明アキモトヨシアキ