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AKIMOTO Yoshiaki  秋元 芳明

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… Alternative Names

秋本 芳明  アキモト ヨシアキ

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Researcher Number 10147720
Other IDs
External Links
Affiliation (based on the past Project Information) *help 2013: 日本大学, 松戸歯学部, 教授
2011 – 2013: 日本大学, 歯学部, 教授
2003 – 2009: Nihon University, School of Dentistry at Matsudo, Professor, 松戸歯学部, 教授
1997 – 2002: 日本大学, 松戸歯学部, 助教授
1999: 日本学部, 松戸歯学部, 助教授
1994 – 1995: 日本大学, 松戸歯学部, 助教授
1990 – 1993: 日本大学, 松戸歯学部, 専任講師
Review Section/Research Field
Principal Investigator
Surgical dentistry / Surgical dentistry / 外科・放射線系歯学
Except Principal Investigator
病態科学系歯学(含放射線系歯学) / Pathobiological dentistry/Dental radiology / Functional basic dentistry / 畜産化学
Keywords
Principal Investigator
分離頻度 / antimicrobial susceptibility / メチシリン耐性黄色ブドウ球菌 / 皮下膿瘍 / 歯性感染症 / Staphylococcus aureus / 感受性 / 黄色ブドウ球菌 / methicillin-resistant Staphylococcus aureus / メチシリン耐性ブドウ球菌 … More / incidence of isolation / odontogenic infection / Staphylococcus epidermidis / 抗菌薬感受性 / 白色ブドウ球菌 / 薬剤感受性 / subcutanus abscess / methicillin-resistant Staphylococcus epidermidis / methicillin-resistant staphylococci / メチシリン耐性白色ブドウ球菌 / Antimicrobial susceptibility / Incidence of isolation / Odontogenic infection / Methicillin-resistant staphylococci / メシシリン耐性白色ブドウ球菌 / subcutaneous abscess / methicillin-resistant coagulase negative staphylococci / コアグラーゼ陰性メチシリン耐性ブドウ球菌 / メチシリン耐性コアグラーゼ陰性ブドウ球菌 / odontogenic and oral infections / incidence / 歯性・口腔感染症 / oral infection / Bーlactamaseの産生能 / MRSA / 口腔感染症 … More
Except Principal Investigator
Nifedipine / カルシウム拮抗薬 / 歯肉線維芽細胞 / ニフェジピン / IL-1α / 歯肉肥厚 / Human Gingival Fibroblast / bFGF / 細胞増殖 / HO-1-N-1 cell / PMA / IL-1β / ESE / NSAID / 歯肉培養線維芽細胞 / 歯肉増殖症 / BMC / BMD / pQCT / 細胞内pH / Gingival Overgrowth / Intracellular Signaling / 蛋白リン酸化 / 細胞内情報伝達 / ブラジキニン / 転写因子 / 細胞周期 / transcription factor / buccal mucosa carcinoma-derived cell / ESE-3 / HO-1-N-1細胞 / 口腔扁平上皮癌由来上皮様細胞 / HO-1-N-1 / gingival overgrowth / cyclin-dependent kinase (CDK) / cyclin / cell growth / cell cycle / gingival fibroblast / nifedipine / p38MAPK / 歯肉増殖 / サイクリン依存性キナーゼ / サイクリン / [Ca^<2+>]i / pHi / protein phosphorylation / Calcium Channel Blocker / 細胞内Ca濃度 / Trabecular bone / Femur / Rat / Mandible / Osteoporosis / 海綿骨 / 下顎骨 / 大腿骨 / ラット / 実験的骨粗鬆症 / Rats and Dogs / Experimental Gingival Overgrowth / ジクロフェナクナトリウム / メフェナム酸 / インドメタシン / テニダップ / 合成抗炎症薬 / 細胞内カルシウム / 歯肉肥厚の治療 / NIFEDIPINE / TENIDAP / Calcium Channel Blockers / リン酸化蛋白質 / cAMP / ヒト歯肉線維芽細胞 / Bradykinin / Intracellular calcium resoinse / Tissue culture / Gingival fibroblasts / Gingival hyperplasia / 細胞内カルシウム濃度 / カルシウム取り込み / コラーゲン合成能 / 線維芽細胞 / カルシウム拮抗剤 / ヒスタミン / フェニトン / DNA合成能 / 細胞内カルシウム応答 / 組織培養 / 炎症性因子 / ets遺伝子 / 薬物性歯肉肥厚 / Ets遺伝子 / フェニトイン / ets-1 / 脂肪抑制像 / T2強調像 / T1強調像 / 被曝のない骨梁解析 / 顎骨の質的評価 / 骨梁の描出 / MRIマイクロスコピーコイル / 磁気共鳴画像検査 / MIC / 血清濃度 / 歯根肉芽腫濃度 / 連続経口投与 / 1回経口投与 / メロフロキサシン Less
  • Research Projects

    (15 results)
  • Research Products

    (13 results)
  • Co-Researchers

    (19 People)
  •  Mechanism of gingival overgrowth caused by medication - Expression and role of ets transcription factor -

    • Principal Investigator
      MATSUMOTO Hiroko
    • Project Period (FY)
      2011 – 2013
    • Research Category
      Grant-in-Aid for Scientific Research (C)
    • Research Field
      Pathobiological dentistry/Dental radiology
    • Research Institution
      Nihon University
  •  Assessment of bone quality of the jaw using MRI microscopy coil

    • Principal Investigator
      KANEDA Takashi
    • Project Period (FY)
      2007 – 2009
    • Research Category
      Grant-in-Aid for Scientific Research (C)
    • Research Field
      Pathobiological dentistry/Dental radiology
    • Research Institution
      Nihon University
  •  Ets family expression in cultured cells from oral tissue

    • Principal Investigator
      MATSUMOTO Hiroko
    • Project Period (FY)
      2004 – 2006
    • Research Category
      Grant-in-Aid for Scientific Research (C)
    • Research Field
      Pathobiological dentistry/Dental radiology
    • Research Institution
      Nihon University
  •  Methicillin-resistant staphylococci isolated from odontogenic infectionPrincipal Investigator

    • Principal Investigator
      AKIMOTO Yoshiaki
    • Project Period (FY)
      2004 – 2006
    • Research Category
      Grant-in-Aid for Scientific Research (C)
    • Research Field
      Surgical dentistry
    • Research Institution
      Nihon University
  •  Cell Growth and Cell Cycle in Nifedipine-Reactive Human Gingival Fibroblasts

    • Principal Investigator
      FUJII Akira, 松本 裕子
    • Project Period (FY)
      2001 – 2003
    • Research Category
      Grant-in-Aid for Scientific Research (C)
    • Research Field
      病態科学系歯学(含放射線系歯学)
    • Research Institution
      Nihon University
  •  Clinical and Bacteriological study of methicillin-resistant staphylococci isolated from odontogenic infection.Principal Investigator

    • Principal Investigator
      AKIMOTO Yoshiaki
    • Project Period (FY)
      2001 – 2003
    • Research Category
      Grant-in-Aid for Scientific Research (C)
    • Research Field
      Surgical dentistry
    • Research Institution
      Nihon University
  •  Mandible Bone Change in Osteoporosis Rats and Therapeutic Treatment

    • Principal Investigator
      AKIRA Fujii
    • Project Period (FY)
      1999 – 2000
    • Research Category
      Grant-in-Aid for Scientific Research (C)
    • Research Field
      病態科学系歯学(含放射線系歯学)
    • Research Institution
      Nihon University
  •  Clarification of Intracellular Signal Transductions in Nifedipine-Reactive Human Gingival Fibroblasts

    • Principal Investigator
      MATSUMOTO Hiroko
    • Project Period (FY)
      1999 – 2000
    • Research Category
      Grant-in-Aid for Scientific Research (C)
    • Research Field
      病態科学系歯学(含放射線系歯学)
    • Research Institution
      Nihon University
  •  TREATMENT OF GINGIVAL OVERGROWTH CAUSED BY MEDICATION

    • Principal Investigator
      FUJII Akira
    • Project Period (FY)
      1998 – 1999
    • Research Category
      Grant-in-Aid for Scientific Research (B)
    • Research Field
      病態科学系歯学(含放射線系歯学)
    • Research Institution
      Nihon University
  •  EFFECT OF NIFEDIPINE ON INTRACELLULAR SIGNAL TRANSDUCTIONS IN HUMAN GINGIVAL FIBROBLASTS

    • Principal Investigator
      FUJII Akira
    • Project Period (FY)
      1997 – 1998
    • Research Category
      Grant-in-Aid for Scientific Research (C)
    • Research Field
      Functional basic dentistry
    • Research Institution
      Nihon University
  •  Incidence of isolation and antimicrobial susceptibility of methicillin-resistant coagulase negative staphylococci isolated from odontogenic infectionPrincipal Investigator

    • Principal Investigator
      AKIMOTO Yoshiaki
    • Project Period (FY)
      1997 – 1998
    • Research Category
      Grant-in-Aid for Scientific Research (C)
    • Research Field
      Surgical dentistry
    • Research Institution
      Nihon University
  •  Incidence of isolation and antimicrobialPrincipal Investigator

    • Principal Investigator
      AKIMOTO Yoshiaki
    • Project Period (FY)
      1994 – 1995
    • Research Category
      Grant-in-Aid for General Scientific Research (C)
    • Research Field
      Surgical dentistry
    • Research Institution
      Nihon University
  •  ロメフロキサシン経口投与後の歯根肉芽腫への移行について

    • Principal Investigator
      金子 賢司
    • Project Period (FY)
      1993
    • Research Category
      Grant-in-Aid for General Scientific Research (C)
    • Research Field
      病態科学系歯学(含放射線系歯学)
    • Research Institution
      Nihon University
  •  Influence (Gingival Hyperplasia) of Nifedipine in Oral Region

    • Principal Investigator
      FUJII Akira
    • Project Period (FY)
      1992 – 1993
    • Research Category
      Grant-in-Aid for General Scientific Research (C)
    • Research Field
      畜産化学
    • Research Institution
      Nihon University
  •  Antimicrobial susceptibilities of methicillin-resistant Staphylococcus aureus isolated from oral infectionPrincipal Investigator

    • Principal Investigator
      AKIMOTO Yoshiaki
    • Project Period (FY)
      1990 – 1992
    • Research Category
      Grant-in-Aid for General Scientific Research (C)
    • Research Field
      外科・放射線系歯学
    • Research Institution
      Nihon University

All 2014 2013 2012 2011

All Journal Article Presentation

  • [Journal Article] The Inhibitory Action of Amlodipine for TNF-α-induced Apoptosis in Cultured Human Gingival Fibroblasts2012

    • Author(s)
      Reiri Takeuchi,Hiroko Matsumoto, Yoshiaki Akimoto,Akira Fujii
    • Journal Title

      Oral Therap Pharmacol

      Volume: 31(2) Pages: 45-52

    • NAID

      10031168920

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-23592779
  • [Journal Article] Inhibition of G1 Cell Cycle Arrest in Human Gingival Fibroblasts Exposed to Phenytoin2012

    • Author(s)
      Reiri Takeuchi,Hiroko Matsumoto, Yoshiaki Akimoto,Akira Fujii
    • Journal Title

      Fundam Clin Pharmacol

      Volume: 2012 Issue: 1 Pages: 1-6

    • DOI

      10.1111/j.1472-8206.2012.01065.x

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-23592779
  • [Journal Article] The Inhibitory, Action of Amlodipine for TNF-α-induced Apopto- sis in Cultured Human Gingival Fibro- blasts2012

    • Author(s)
      Takeuchi R,Matsumoto H,Akimoto Y,Fujii A
    • Journal Title

      歯科薬物療法

      Volume: 31(2) Pages: 45-52

    • NAID

      10031168920

    • URL

      https://www.jstage.jst.go.jp/browse/jsotp/31/2/_contents/-char/ja

    • Data Source
      KAKENHI-PROJECT-23592779
  • [Presentation] Effect of phenytoin on caspase activity in cultured human gingival fibroblasts2014

    • Author(s)
      Reiri Takeuchi, Makiko Ono, Yoshiaki Akimoto, Akira Fujii, Hiroko Matsumoto
    • Organizer
      第34回日本歯科薬物療法学会
    • Place of Presentation
      大阪歯科大学創立100周年記念館(大阪)
    • Data Source
      KAKENHI-PROJECT-23592779
  • [Presentation] 18-alpha- glycyrrhetinic acid suppresses G1/S- phase transition and induces apoptosis in gingival fibroblast isolated from a patient that presented with nifedi- pine-induced gingival overgrowth2014

    • Author(s)
      Takeuchi R, Ono M, Arikawa K, Akimoto Y, Fujii A, Matsumoto H
    • Organizer
      17th World Congress on Basic & Clinical Pharmacology
    • Place of Presentation
      Cape Town International Convention Center (Cape Town)
    • Year and Date
      2014-07-13
    • Data Source
      KAKENHI-PROJECT-23592779
  • [Presentation] 18-alpha-glycyrrhetinic acid suppresses G1/S-phase transition and induces apoptosis in gingival fibroblast isolated from a patient that presented with nifedipine-induced gingival overgrowth2014

    • Author(s)
      Reiri Takeuchi, Makiko Ono, Kazumune Arikawa, Yoshiaki Akimoto, Akira Fujii, Hiroko Matsumoto
    • Organizer
      17th World Congress on Basic & Clinical Pharmacology
    • Place of Presentation
      Cape Town International Convention Centre (Cape Town)
    • Data Source
      KAKENHI-PROJECT-23592779
  • [Presentation] Effect of phenytoin on caspase activity in cultured human gingival fibroblasts2014

    • Author(s)
      Takeuchi R, Ono M, Akimoto Y, Fujii A, Matsumoto H
    • Organizer
      第34回日本歯科薬物療法学会
    • Place of Presentation
      大阪歯科大学(大阪)
    • Year and Date
      2014-06-21
    • Data Source
      KAKENHI-PROJECT-23592779
  • [Presentation] Tentative Pharmaco- therapy for Nifedipine-induced Gin- gival Overgrowth using 18α-glycyr- rhetinic Acid2013

    • Author(s)
      Takeuchi R, Ono M, Akimoto Y, Fujii A, Matsumoto H
    • Organizer
      第33回日本歯科薬物療法学会
    • Place of Presentation
      東京医科歯科大学(東京)
    • Year and Date
      2013-06-14
    • Data Source
      KAKENHI-PROJECT-23592779
  • [Presentation] Tentative Pharmacotherapy for Nifedipine-induced Gingival Overgrowth using 18α-glycyrrhetinic Acid2013

    • Author(s)
      Reiri Takeuchi, Makiko Ono, Yoshiaki Akimoto, Akira Fujii, Hiroko Matsumoto
    • Organizer
      第33回日本歯科薬物療法学会
    • Place of Presentation
      東京医科歯科大学(東京)
    • Data Source
      KAKENHI-PROJECT-23592779
  • [Presentation] The Mechanism of Phenytoin-induced Gingival Overgrowth2012

    • Author(s)
      Reiri Takeuchi,Hiroko Matsumoto, Yoshiaki Akimoto,Akira Fujii
    • Organizer
      第32回日本歯科薬物療法学会
    • Place of Presentation
      大阪国際会議場(大阪)
    • Data Source
      KAKENHI-PROJECT-23592779
  • [Presentation] The Mechanism of Phenytoin- induced Gingival Overgrowth2011

    • Author(s)
      Takeuchi R, Matsumoto H, Akimoto Y, Fujii A
    • Organizer
      第32回日本歯科薬物療法学会
    • Place of Presentation
      大阪国際会議場(大阪)
    • Year and Date
      2011-06-30
    • Data Source
      KAKENHI-PROJECT-23592779
  • [Presentation] The Mechanism of Nifedipine- induced Gingival Overgrowth2011

    • Author(s)
      Takeuchi R, Matsumoto H, Akimoto Y, Fujii A
    • Organizer
      第53回歯科基礎医学会
    • Place of Presentation
      長良川国際会議場(岐阜)
    • Year and Date
      2011-10-02
    • Data Source
      KAKENHI-PROJECT-23592779
  • [Presentation] アムロジピンによる歯肉肥厚の発症機序2011

    • Author(s)
      松本裕子,竹内麗理,小野眞紀子,秋元芳明,藤井彰
    • Organizer
      第13回応用薬理シンポジウム
    • Place of Presentation
      日本大学薬学部(船橋)
    • Year and Date
      2011-09-04
    • Data Source
      KAKENHI-PROJECT-23592779
  • 1.  FUJII Akira (70102564)
    # of Collaborated Projects: 14 results
    # of Collaborated Products: 0 results
  • 2.  MATSUMOTO Hiroko (50221594)
    # of Collaborated Projects: 13 results
    # of Collaborated Products: 13 results
  • 3.  YAMAMOTO Hirotsugu (00102591)
    # of Collaborated Projects: 5 results
    # of Collaborated Products: 0 results
  • 4.  SHIBUTANI Jun (20206147)
    # of Collaborated Projects: 5 results
    # of Collaborated Products: 0 results
  • 5.  ONO Makiko (00267113)
    # of Collaborated Projects: 4 results
    # of Collaborated Products: 0 results
  • 6.  NISHIMURA Hitoshi (10198509)
    # of Collaborated Projects: 3 results
    # of Collaborated Products: 0 results
  • 7.  KANEDA Takashi (40185947)
    # of Collaborated Projects: 2 results
    # of Collaborated Products: 0 results
  • 8.  MORI Shintaro (40419792)
    # of Collaborated Projects: 1 results
    # of Collaborated Products: 0 results
  • 9.  OKADA Hiroyuki (70256890)
    # of Collaborated Projects: 1 results
    # of Collaborated Products: 0 results
  • 10.  TAKEUCHI Reiri (60419778)
    # of Collaborated Projects: 1 results
    # of Collaborated Products: 13 results
  • 11.  MOCHIZUKI Yoshiko (90200336)
    # of Collaborated Projects: 1 results
    # of Collaborated Products: 0 results
  • 12.  KOMIYA Masamichi (40186812)
    # of Collaborated Projects: 1 results
    # of Collaborated Products: 0 results
  • 13.  HIRAYAMA Teruyasu (10189871)
    # of Collaborated Projects: 1 results
    # of Collaborated Products: 0 results
  • 14.  金子 賢司 (20050007)
    # of Collaborated Projects: 1 results
    # of Collaborated Products: 0 results
  • 15.  小俣 裕昭 (10241100)
    # of Collaborated Projects: 1 results
    # of Collaborated Products: 0 results
  • 16.  加藤 正隆 (40434097)
    # of Collaborated Projects: 1 results
    # of Collaborated Products: 0 results
  • 17.  山根 潤一 (20220428)
    # of Collaborated Projects: 1 results
    # of Collaborated Products: 0 results
  • 18.  中尾 寿美 (20102577)
    # of Collaborated Projects: 1 results
    # of Collaborated Products: 0 results
  • 19.  池田 眞紀子
    # of Collaborated Projects: 0 results
    # of Collaborated Products: 7 results

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