KUDO Naomi 工藤なをみ

… Alternative Names

工藤なをみクドウナオミ

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Researcher Number	10161647
Other IDs
Affiliation (Current)	2025: 城西大学, 薬学部, 教授
Affiliation (based on the past Project Information) *help	2007 – 2008: Josai University, 薬学部, 准教授 2006: 城西大学, 薬学部, 助教授 2002 – 2005: Josai University, Faculty of Pharmaceutical Sciences, Lecturer, 薬学部, 講師 2002: Josai University, Faculty of Pharmaceutical Science, Research Associate 1996 – 2002: 城西大学, 薬学部, 助手 1995: 帝京大学, 薬学部, 助手 1993: 帝京大学, 薬学部, 助手
Review Section/Research Field	Principal Investigator Risk sciences of radiation/Chemicals / 環境影響評価(含放射線生物学) / 医薬分子機能学 / Functional biochemistry Except Principal Investigator Metabolomics / Biological pharmacy / Functional biochemistry
Keywords	Principal Investigator ペルフルオロオクタン酸 / 吸収 / 代謝 / perfluorooctanoic acid / ペルオキシソーム増殖 / oleic acid formation / Peroxisome proliferation / metabolism / 8-2 fluorotelomer alcohol / 蓄積 … More / オレイン酸合成酵素 / ペルフルオロアルキルテロマーアルコール / 酵素発現 / オレイン酸 / 脂肪酸合成 / オレイン酸合成 / 8-2テロマーアルコール / intestinal absorption / sex hormone / organic anion transporter / renal clearance / perfluooctanoic acid / 腎排泄 / フッ素化脂肪酸 / 消化管吸収 / 性ホルモン / 有機酸トランスポーター / 腎クリアランス / 1H,1H,2H,2H-ペルフルオロオクタノール / 肝細胞内分布 / 2H,2H,3H,3H-ペルフルオロノナデカン酸 / 2H,2H-ペルフルオロノナデカン酸 / 1H,1H,2H,2H-ペルフルオロデカノール / 生体作用 / 2H,2H,3H,3H-perfluorodecanoic acid / 2H,2H-perfluorodecanoic acid / 細胞内分布 / 生体内蓄積 / 1H,1H,2H,2H-perfluorodecanol / 排泄 / 尿中排泄 / 性差 / 炭素鎖長 / ペルフルオロ脂肪酸 / 虚血-再潅流 / アセチルCoAカルボキシラーゼ / 5′AMP活性化蛋白リン酸化酵素 / ロイコトリエン / 活性酸素 / 重金属 / 肺胞マクロファージ / 肺障害 … More Except Principal Investigator VLDL分泌 / fatty acid / dehydroepiandrosterone / insulin / palmitoyl-CoA chain elongase / clofibric acid / △9 desaturase / PPAR / 糖尿病 / 脂肪酸酸化 / 脂肪酸 / デヒドロエピアンドロステロン / インスリン / パルミトイルCoA炭素鎖伸長酵素 / クロフィブリン酸 / Δ9不飽和化酵素 / testosterone / urinary excretion / hepatic accumulation / lipid metabolism / peroxisomal B-oxidation / VLDL excretion / fatty liver / perfruorinated fatty acids / 肝腫大 / 脂質代謝 / 脂肪肝 / 肝TG蓄積 / パルフルオロ脂肪酸 / テストステロン / 尿排泄 / 肝残存性 / 肝脂質代謝 / ペルオキシソームβ酸化 / 肝脂肪蓄積 / ペルフルオロ脂肪酸 / アナンダマイド / グルクロニルトランスフェラーゼ / アシルトランスフェラーゼ / アシルCoA Less

Is the metabolic activation involved in the toxicity of perfluorinated chemicals ?Principal Investigator
- Principal Investigator
  
  KUDO Naomi
- Project Period (FY)
  2006 – 2008
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Research Field
  
  Risk sciences of radiation/Chemicals
- Research Institution
  Josai University
Studies on toxicokinetics of perfluoroaklyltelomer alcohol in experimental animals and its application to the estimation of accumulation in humansPrincipal Investigator
- Principal Investigator
  
  KUDO Naomi
- Project Period (FY)
  2003 – 2005
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Research Field
  
  Risk sciences of radiation/Chemicals
- Research Institution
  Josai University
Studies on the regulation of fatty acid biosynthesis by drugs
- Principal Investigator
  
  KAWASHIMA Yoichi
- Project Period (FY)
  2000 – 2002
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Research Field
  
  Metabolomics
- Research Institution
  Josai University
Analysis of the mechanisms of absorption and elimination of chemical products in cultured cells and its application for estimation of the toxicity in vivoPrincipal Investigator
- Principal Investigator
  
  KUDO Naomi
- Project Period (FY)
  2000 – 2002
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Research Field
  
  環境影響評価(含放射線生物学)
- Research Institution
  Josai University
フッ素化脂肪酸化合物を認識する新規細胞膜輸送体の検索とそのクローニングPrincipal Investigator
- Principal Investigator
  
  工藤なをみ
- Project Period (FY)
  1997 – 1998
- Research Category
  
  Grant-in-Aid for Encouragement of Young Scientists (A)
- Research Field
  
  医薬分子機能学
- Research Institution
  Josai University
Study on the variety of the effects of perfluorinated fatty acids on biological systems and the biological mechanisms for identification of each molecules.
- Principal Investigator
  
  KAWASHIMA Yoichi
- Project Period (FY)
  1997 – 1999
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Research Field
  
  Biological pharmacy
- Research Institution
  Josai University
心臓の5′AMP活性化蛋白リン酸化酵素の生理的役割と調節機構の解明に関する研究Principal Investigator
- Principal Investigator
  
  工藤なをみ
- Project Period (FY)
  1996
- Research Category
  
  Grant-in-Aid for Encouragement of Young Scientists (A)
- Research Field
  
  Functional biochemistry
- Research Institution
  Josai University
アシルCoAの生合成・代謝及び生理学的意義の総合的研究
- Principal Investigator
  
  和久敬蔵
- Project Period (FY)
  1995
- Research Category
  
  Grant-in-Aid for General Scientific Research (C)
- Research Field
  
  Functional biochemistry
- Research Institution
  Teikyo University
環境汚染物質による肺の障害機構とマクロファージの役割の解明Principal Investigator
- Principal Investigator
  
  工藤なをみ
- Project Period (FY)
  1993
- Research Category
  
  Grant-in-Aid for Encouragement of Young Scientists (A)
- Research Field
  
  環境影響評価(含放射線生物学)
- Research Institution
  Teikyo University

All 2009 2008 2007 2006 2005 2004

All Journal Article Presentation

[Journal Article] Rat organic anion transporter 3 and organic anion transporting polypeptide 1 mediate perfluorooctanoic acid transport J.2007
- Author(s)
  Katakura, M., Kudo, N., Tsuda, T., Hibino, Y., Mitsumoto A. and Kawashima, Y.
- Journal Title
  
  Health Science 53
  
  Pages: 77-83
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-18510063
[Journal Article] Tissue distribution and subcellular distribution of peprfluorooctanoic acid at low dose are different from those at high dose in rats.2007
- Author(s)
  Kudo, N., Sakai, A., Mitsumoto, A., Hibino, Y., Tsuda, T. and Kawashima, Y.
- Journal Title
  
  Biol. Pharm. Bull. 30
  
  Pages: 1535-1540
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-18510063
[Journal Article] Tissue distribution and hepatic subcellular distribution of perfluoro octanoic acid at low dose are different from those at high dose in rats2007
- Author(s)
  Kudo N., Sakai A., Mitsumoto A., Hibino Y., Tsuda T., Kawashima,Y
- Journal Title
  
  Biol. Pharm. Bull. 30
  
  Pages: 1535-1540
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-18510063
[Journal Article] Effects of 8-2 fluorotelomer alcohol on oleic acid formation in the liver of rats.2006
- Author(s)
  Iwase, Y., Kudo, N., Kawashima, Y.
- Journal Title
  
  Biol.Pharm.Bull. (in press)
- NAID
  120006455238
- Description
  「研究成果報告書概要(欧文)」より
- Data Source
  KAKENHI-PROJECT-15510060
[Journal Article] Effect of 8-2 fluorotelomer alcohol on oleic acid formation in the liver of rats.2006
- Author(s)
  Iwase, Y., Kudo, N., Tamura, M., Mitsumoto, A., Kawashima, Y.
- Journal Title
  
  Biol. Pharm. Bull. 29
  
  Pages: 1740-1746
- NAID
  120006455238
- Data Source
  KAKENHI-PROJECT-18510063
[Journal Article] Effects of 8-2 fluorotelomer alcohol on oleic acid formation in the liver of rat.2006
- Author(s)
  Iwase, Y., Kudo, N., et al.
- Journal Title
  
  Biol. Pharm. Bull. (In press)
- NAID
  120006455238
- Description
  「研究成果報告書概要(和文)」より
- Data Source
  KAKENHI-PROJECT-15510060
[Journal Article] Responses of the liver to perfluorinated fatty acids with different carbon chain length in male and female mice:In relation to induction of hepatomegaly, peroxisomal β-oxidation and microsomal 1-acylglycerophosphocholine acyltransferase.2006
- Author(s)
  Kudo, N., Suzuki-Nakajima, E., Mitsumoto, A. and Kawashima, Y.
- Journal Title
  
  Biol. Pharm. Bull. 29
  
  Pages: 1952-1957
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-18510063
[Journal Article] Effect of 8-2 fluorotelomer alcohol on oleic acid formation in the liver of rats. Biol.2006
- Author(s)
  Iwase, Y., Kudo, N., Toyama, T., Tamura, M., Mitsumoto, A. and Kawashima, Y.
- Journal Title
  
  Pharm. Bull. 29
  
  Pages: 1740-1746
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-18510063
[Journal Article] Induction of hepatic peroxisome proliferation by 8-2 telomer alcohol feeding in mice : Formation of perfluorooctanoic acid in the liver2005
- Author(s)
  Kudo, N., Iwase, Y., Kawashima, Y.
- Journal Title
  
  Toxicological Science s (in press)
- Data Source
  KAKENHI-PROJECT-15510060
[Journal Article] Induction of hepatic peroxisome proliferation by 8-2 telomer alcohol feeding in mice : Formation of perfluorooctanoic acid.2005
- Author(s)
  Kudo, N., Iwase, Y., Okayachi, H., Yamakawa, Y., Kawashima, Y.
- Journal Title
  
  Toxicological Sciences 86
  
  Pages: 231-238
- Description
  「研究成果報告書概要(和文)」より
- Data Source
  KAKENHI-PROJECT-15510060
[Journal Article] Induction of Peroxisome proliferation by 8-2 fluorotelomer alcohol feeding in mice : formation of perfluorooctanoic acid.2005
- Author(s)
  Kudo, N., Iwase, Y., Okayachi, H., Yamakawa, Y., Kawashima, Y.
- Journal Title
  
  Toxicol.Sci. 86
  
  Pages: 231-238
- Description
  「研究成果報告書概要(欧文)」より
- Data Source
  KAKENHI-PROJECT-15510060
[Journal Article] Effects of perfluorinated carboxylic acids on the activities of fatty acid elongations in the liver of rats in vivo and in vitro.2004
- Author(s)
  Toyama, T., Mitsumoto, A., Kudo, N., Kawashima, Y.
- Journal Title
  
  Chemico-Biol. Interact. 150
  
  Pages: 189-198
- Description
  「研究成果報告書概要(和文)」より
- Data Source
  KAKENHI-PROJECT-15510060
[Journal Article] Effects of perfluorinated carboxylic acids on the activities of fatty acid elongations in the liver of rats in vivo and in vitro.2004
- Author(s)
  Toyama, T., Mitsumoto, A., Kudo, N., Kawashima, Y.
- Journal Title
  
  Chemico-Biol.Interact. 150
  
  Pages: 189-198
- Description
  「研究成果報告書概要(欧文)」より
- Data Source
  KAKENHI-PROJECT-15510060
[Presentation] 2H,2H-perfluorodecanoic acid のマウスに対する影響2009
- Author(s)
  鎌苅有華、工藤なをみ、川嶋洋一
- Organizer
  日本薬学会第129年会
- Data Source
  KAKENHI-PROJECT-18510063
[Presentation] ペルフルオロオクタン酸の肝細胞内分布のホルモンによる調節2009
- Author(s)
  畑幸江、工藤なをみ、川嶋洋一
- Organizer
  日本薬学会第129年会
- Data Source
  KAKENHI-PROJECT-18510063
[Presentation] 2H, 2H-perfluorodecanoic acid のマウスに対する影響2009
- Author(s)
  鎌苅由華, 工藤なをみ, 川嶋洋一
- Organizer
  日本薬学会第129年会
- Place of Presentation
  京都
- Year and Date
  2009-03-26
- Data Source
  KAKENHI-PROJECT-18510063
[Presentation] ペルフルオロオクタン酸の肝細胞内分布のホルモンによる調節2009
- Author(s)
  畑幸江, 工藤なをみ, 川嶋洋一
- Organizer
  日本薬学会第129年会
- Place of Presentation
  京都
- Year and Date
  2009-03-26
- Data Source
  KAKENHI-PROJECT-18510063
[Presentation] 種々のフッ素系界面活性剤の体内動態の解析2008
- Author(s)
  西畑ちづる、工藤なをみ、川嶋洋一
- Organizer
  日本薬学会第128年会
- Data Source
  KAKENHI-PROJECT-18510063
[Presentation] フッ素系界面活性剤の長期暴露による生体残留性と影響評価2007
- Author(s)
  柳原光雄、外山智章、工藤なをみ、川嶋洋一
- Organizer
  日本薬学会第127年会
- Data Source
  KAKENHI-PROJECT-18510063
[Presentation] 低用量慢性暴露時のペルフルオロオクタン酸の体内分布2007
- Author(s)
  酒井絢子、工藤なをみ、川嶋洋一
- Organizer
  日本薬学会第127年会
- Data Source
  KAKENHI-PROJECT-18510063
[Presentation] 1H,1H,2H,2H-perfluorodecanol は脂質代謝を変える2007
- Author(s)
  岩瀬由布子、田村雅史、工藤なをみ、川嶋洋一
- Organizer
  日本薬学会第127年会
- Data Source
  KAKENHI-PROJECT-18510063
[Presentation] 微量ペルフルオロオクタン酸の生体内残留性2006
- Author(s)
  酒井絢子、工藤なをみ、川嶋洋一
- Organizer
  フォーラム2006:衛生薬学・環境トキシコロジー
- Data Source
  KAKENHI-PROJECT-18510063

1. KAWASHIMA Yoichi (80126515)

# of Collaborated Projects: 2 results

# of Collaborated Products: 0 results
2. 藤兼裕子

# of Collaborated Projects: 2 results

# of Collaborated Products: 0 results
3. IWASE Yuko (80406371)

# of Collaborated Projects: 1 results

# of Collaborated Products: 3 results
4. OHYA Takeshi (90077975)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
5. 和久敬蔵 (90013854)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
6. 山下純 (80230415)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
7. 杉浦隆之 (40130009)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
8. MIURA Hiroaki

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
9. IMAI Koichi

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
10. FUJIKANE Yuko

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results

KUDO Naomi 工藤 なをみ

工藤 なをみ クドウ ナオミ

Research Projects

Research Products

Co-Researchers

Is the metabolic activation involved in the toxicity of perfluorinated chemicals ?Principal Investigator

Principal Investigator

Project Period (FY)

Research Category

Research Field

Research Institution

Studies on toxicokinetics of perfluoroaklyltelomer alcohol in experimental animals and its application to the estimation of accumulation in humansPrincipal Investigator

Principal Investigator

Project Period (FY)

Research Category

Research Field

Research Institution

Studies on the regulation of fatty acid biosynthesis by drugs

Principal Investigator

Project Period (FY)

Research Category

Research Field

Research Institution

Analysis of the mechanisms of absorption and elimination of chemical products in cultured cells and its application for estimation of the toxicity in vivoPrincipal Investigator

Principal Investigator

Project Period (FY)

Research Category

Research Field

Research Institution

フッ素化脂肪酸化合物を認識する新規細胞膜輸送体の検索とそのクローニングPrincipal Investigator

Principal Investigator

Project Period (FY)

Research Category

Research Field

Research Institution

Study on the variety of the effects of perfluorinated fatty acids on biological systems and the biological mechanisms for identification of each molecules.

Principal Investigator

Project Period (FY)

Research Category

Research Field

Research Institution

心臓の5′AMP活性化蛋白リン酸化酵素の生理的役割と調節機構の解明に関する研究Principal Investigator

Principal Investigator

Project Period (FY)

Research Category

Research Field

Research Institution

アシルCoAの生合成・代謝及び生理学的意義の総合的研究

Principal Investigator

Project Period (FY)

Research Category

Research Field

Research Institution

環境汚染物質による肺の障害機構とマクロファージの役割の解明Principal Investigator

Principal Investigator

Project Period (FY)

Research Category

Research Field

Research Institution

[Journal Article] Rat organic anion transporter 3 and organic anion transporting polypeptide 1 mediate perfluorooctanoic acid transport J.2007

Author(s)

Journal Title

Data Source

[Journal Article] Tissue distribution and subcellular distribution of peprfluorooctanoic acid at low dose are different from those at high dose in rats.2007

Author(s)

Journal Title

Data Source

[Journal Article] Tissue distribution and hepatic subcellular distribution of perfluoro octanoic acid at low dose are different from those at high dose in rats2007

Author(s)

Journal Title

Data Source

[Journal Article] Effects of 8-2 fluorotelomer alcohol on oleic acid formation in the liver of rats.2006

Author(s)

Journal Title

NAID

Description

Data Source

[Journal Article] Effect of 8-2 fluorotelomer alcohol on oleic acid formation in the liver of rats.2006

Author(s)

Journal Title

KUDO Naomi 工藤なをみ

工藤なをみクドウナオミ