ISHII KUNIAKI 石井邦明

… Alternative Names

ISHII Kuniaki 石井邦明

石井邦明イシイクニアキ

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Researcher Number	10184459
Other IDs
Affiliation (based on the past Project Information) *help	2021 – 2023: 山形大学, 医学部, 非常勤講師 2020: 山形大学, 医学部, 教授 2014 – 2016: 山形大学, 医学部, 教授 2010 – 2012: 山形大学, 医学部, 教授 2006: Yamagata University, Cardiovascular Pharmacology, Professor, 医学部, 教授 … More 1996 – 2005: Yamagata Univ., Dept.of Pharmacol., Assoc.Prof., 医学部, 助教授 1995: Tohoku University, School of Medicine, lecturer, 医学部, 講師 1993 – 1994: 東北大学, 医学部, 助手 1988 – 1989: 東北大学, 医学部, 助手 Less
Review Section/Research Field	Principal Investigator General pharmacology / 応用薬理学・医療系薬学 / General pharmacology / Basic Section 47040:Pharmacology-related Except Principal Investigator General pharmacology / 応用薬理学・医療系薬学 / General pharmacology / 神経・脳内生理学
Keywords	Principal Investigator Herg / HERG / 第6膜貫通領域 / 抗不整脈薬 / サブユニット / 脱活性化 / MS-551 / 内向き整流 / 心筋 / Kチャネル … More / チャネル / 受容体 / 電位依存性K^+チャンネル / インターナリゼーション / 受容体刺激 / charged amino acids / ion selectivity / inward currents / outward currents / activation gate / voltage sensor / 荷電アミノ酸 / イオン選択性 / 内向き電流 / 外向き電流 / 活性化ゲート / 電位センサー / oocyte / tandem / sixth transmembrane region / amino-terminal region / deactivation / 卵母細胞 / タンデム / アミノ末端領域 / protein kinase C / protein kinase A / tyrosine kinase / phosphorylation / human cardiac delayed rectifier / PYK2 / 共発現系 / K^+チャネル / プロテインキナーゼC / プロテインキナーゼA / チロシンキナーゼ / リン酸化 / ヒト心筋遅延整流型K^+チャネル / 点変異 / 遅延整流型K^+電流 / verapamil / quinidine / antiarrhythmic drugs / K^+ channel clones / ベラパミル / キニジン / K^+チャンネルクローン / Single channel current / patch clamp / heart / inward rectification / cloned k channel / 単一チャンネル電流 / パッチクランプ / Kチャンネルクローン / pH感受性 / pH / GFP変異体 / 心臓 / イメージング / シグナル情報伝達系 / 電位依存性Kチャネル / エンドサイトーシス / 電位依存性 Kチャネル … More Except Principal Investigator Xenopus oocyte / エンドセリン / Caトランジェント / Kv1.4 / プロテインキナーゼC / Na-Ca交換機構 / Na^+ / norepinephrine / ノルエピネフリン / クロストーク / PKC / dominant negative / phosphorylation / リン酸化 / cGMP / Na-H交換機構 / アンジオテンシンII / Kv1.2 / Ca^<2+> exchanger / endothelin / force-frequency relationship / Ca^<2+> mobilizers / Ca^<2+> sensitizers / dog ventricular cardiomyocytes / mouse ventricular cardiomyocytes / Y-27632 / wortomannin / 哺乳類心室筋 / アンギオテンシンII / 収縮タンパクCa^<2+>感受性 / ミオシン軽鎖 / ワートマニン / Rhoキナーゼ / 単離心室筋細胞 / Ca^<2+>感受性 / Ca^<2+>動員機構 / Ca^<2+>トランジェント / Ca^<2+>交換機構 / 頻度・収縮関係 / Ca^<2+>モビライザー / Ca^<2+>センシタイザー / イヌ心室筋細胞 / マウス心室筋細胞 / protein kinase C / protein kinase A / Ca transient / Ca signal / cardiac contractility / endothelin-1 / crosstalk / エクオリン / アシドーシス / 心筋細胞 / Caセンシタイザー / イヌ心室筋 / マウス心筋細胞 / プロテインキナーゼA / Caシグナル / 心筋収縮 / エンドセリン-1 / anchoring protein / K^+ channel / K^+チャンネル / アンカリングプロテイン / K^+チャネル / Positive inotropic effect / Protein kinase C / Rabbit ventricular myocytes / Increased Ca^<2+> sensitivity / Ca^<2+> transients / Intracellular alkalinization / Na^+-H^+ exchange / Na^+-Ca^<2+> exchange / L型Ca電流 / ウサギ心室筋細胞 / KB-R7943 / Ethylisopropylamiloride / Ca交換機構 / H交換機構 / Na / 陽性変力作用 / 心室筋細胞、ウサギ / Ca感受性増強 / 細胞内アルカリ化 / multimetric cDNA / inactivation balls / Kvl.4 / mubimeric cDNA / 不活性化ゲート / Xenopus Oocyte / multimeric cDNA / 不活性ゲート / presynaptic terminal / transmitter release / protein kinase G / guanylyl cyclase / adrenergic receptor / noradrenaline / カルシウム / シナプス可塑性 / 開口放出 / プロテインキナーゼ / 一酸化窒素 / サイクリックGMP(cGMP) / シナプス前終末 / 伝達物質放出 / G-キナーゼ / グアニル酸シクラーゼ / アドレナリン性受容体 / ノルアドレナリン / ホスフォイノシタイド / α受容体 / Na^+-Ca^<2+>交感機構 / KB-R 7943 / エンドセチン受容体 / アンジオテンシンII受容体 / Na^+Ca^<2+>交感機構 / KB-R・7943 / Na^+-H^+交感機構 / エチルイソプロピルアミロライド / エンドセリン受容体 / アンジオテンシンII 受容体 / 交感神経の受容体 / tandem linkage / inactivation / hybrid K channel / ハイブリッドチャンネル / 電位依存性Kチャンネル / タンデム連結 / 不活性化 / ハイブリッドKチャンネル / inward rectifier / transient outward / delayd rectifier / cloned K channels / antiarrhythmic drugs / 内向き整流電流 / 内向き整流性電流 / 一過性外向き電流 / 遅延整流型電流 / Kチャンネルクローン / 抗不整脈薬 / レセプター / 内向き整流性K電流 / BRL34915 / Kチャンネル開孔薬 / Kチャンネル開口薬レセプター / Kチャンネル開口薬レセプタ- / glibenclamide / nicorandil / pinacidil / cromakalim / Kチャンネル開口薬 / Kチャンネル / H3受容体 / ヒスタミン受容体 / ヒスタミン Less

Pathophysiological significance of decreased K channel expression by receptor activationPrincipal Investigator
- Principal Investigator
  
  石井邦明
- Project Period (FY)
  2020 – 2024
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Review Section
  
  Basic Section 47040:Pharmacology-related
- Research Institution
  Yamagata University
Imaging of quantitative changes in surface expression of ion channels using isolated perfused heartsPrincipal Investigator
- Principal Investigator
  
  ISHII KUNIAKI
- Project Period (FY)
  2014 – 2016
- Research Category
  
  Grant-in-Aid for Challenging Exploratory Research
- Research Field
  
  General pharmacology
- Research Institution
  Yamagata University
Endocytosis of human K channel by receptor activation and its intracellular mechanismsPrincipal Investigator
- Principal Investigator
  
  ISHII Kuniaki
- Project Period (FY)
  2010 – 2012
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Research Field
  
  General pharmacology
- Research Institution
  Yamagata University
Molecular pharmacological research for regulation and disorder of cardiac myocytes
- Principal Investigator
  
  ENDOH Masao
- Project Period (FY)
  2004 – 2006
- Research Category
  
  Grant-in-Aid for Scientific Research (B)
- Research Field
  
  General pharmacology
- Research Institution
  Yamagata University
Identification of the activation gate of HERG K^+ channelPrincipal Investigator
- Principal Investigator
  
  ISHII Kuniaki
- Project Period (FY)
  2002 – 2004
- Research Category
  
  Grant-in-Aid for Scientific Research (B)
- Research Field
  
  General pharmacology
- Research Institution
  Yamagata University
Basic research for regulation and disorder of cardiac Ca signal
- Principal Investigator
  
  ENDOH Masao
- Project Period (FY)
  2002 – 2003
- Research Category
  
  Grant-in-Aid for Scientific Research (B)
- Research Field
  
  応用薬理学・医療系薬学
- Research Institution
  Yamagata University
Possible involvement of PKC anchoring protein in the modulation of voltage-dependent K^+ channels by endothelin
- Principal Investigator
  
  NUNOKI Kazuo
- Project Period (FY)
  2001 – 2002
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Research Field
  
  General pharmacology
- Research Institution
  Tohoku University
Molecular mechanisms of the slow deactivation of HERG channelPrincipal Investigator
- Principal Investigator
  
  ISHII Kuniaki
- Project Period (FY)
  2000 – 2001
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Research Field
  
  General pharmacology
- Research Institution
  Yamagata University
MORECULAR PHARMACOLOGICAL STUDY OF SIGNAL TRANSDUCTION
- Principal Investigator
  
  ENDOH Masao
- Project Period (FY)
  1999 – 2000
- Research Category
  
  Grant-in-Aid for Scientific Research (B)
- Research Field
  
  General pharmacology
- Research Institution
  YAMAGATA UNIVERSITY SCHOOL OF MEDICINE
Involvement of tyrosine kinase in regulation of ion channel functions and crosstalk between signal transduction systemsPrincipal Investigator
- Principal Investigator
  
  ISHII Kuniaki
- Project Period (FY)
  1998 – 1999
- Research Category
  
  Grant-in-Aid for Scientific Research (B)
- Research Field
  
  General pharmacology
- Research Institution
  Yamagata University
Inactivation rate constant and the number of inactivation gates
- Principal Investigator
  
  NUNOKI Kazuo
- Project Period (FY)
  1998 – 1999
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Research Field
  
  General pharmacology
- Research Institution
  TOHOKU UNIVERSITY
ホスフォイノシタイド代謝共役受容体シグナル伝達機構の分子薬理学的分析
- Principal Investigator
  
  ENDOH Masao
- Project Period (FY)
  1997 – 1998
- Research Category
  
  Grant-in-Aid for Scientific Research (B)
- Research Field
  
  General pharmacology
- Research Institution
  Yamagata University
Analysis of presynaptic guanylyl cyclase cascade during adrenergic enhancement of transmitter release
- Principal Investigator
  
  YAWO Hiromu
- Project Period (FY)
  1997 – 1999
- Research Category
  
  Grant-in-Aid for Scientific Research (B)
- Research Field
  
  神経・脳内生理学
- Research Institution
  TOHOKU UNIVERSITY
致死的不整脈原因遺伝子の発現系の確立とその抗不整脈薬への応用Principal Investigator
- Principal Investigator
  
  石井邦明
- Project Period (FY)
  1997 – 1998
- Research Category
  
  Grant-in-Aid for Scientific Research (B)
- Research Field
  
  応用薬理学・医療系薬学
- Research Institution
  Yamagata University
電位依存性K^+チャンネルの機能調節分子に関する研究Principal Investigator
- Principal Investigator
  
  石井邦明
- Project Period (FY)
  1996
- Research Category
  
  Grant-in-Aid for Scientific Research on Priority Areas
- Research Institution
  Yamagata University
電位依存性K^+チャンネルの機能調節分子に関する研究Principal Investigator
- Principal Investigator
  
  石井邦明
- Project Period (FY)
  1995
- Research Category
  
  Grant-in-Aid for Scientific Research on Priority Areas
- Research Institution
  Tohoku University
Reconstruction of native K^+ channels by use of cloned K^+ channels and its application to the development of antiarrhythmic agents.Principal Investigator
- Principal Investigator
  
  ISHII Kuniaki
- Project Period (FY)
  1995 – 1996
- Research Category
  
  Grant-in-Aid for Scientific Research (A)
- Research Field
  
  応用薬理学・医療系薬学
- Research Institution
  Yamagata University
  Tohoku University
Research on inactivation of the hybrid K channel.
- Principal Investigator
  
  NUNOKI Kazuo
- Project Period (FY)
  1995 – 1996
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Research Field
  
  General pharmacology
- Research Institution
  Tohoku University
Cloning of a cardiac inward rectifier k^+ channel and its gating mechanismsPrincipal Investigator
- Principal Investigator
  
  ISHII Kuniaki
- Project Period (FY)
  1994 – 1995
- Research Category
  
  Grant-in-Aid for General Scientific Research (C)
- Research Field
  
  General pharmacology
- Research Institution
  Tohoku University
中枢ヒスタミンの遊離・合成の調節機構:前シナプス性H_3受容体のクローニング
- Principal Investigator
  
  渡邉建彦
- Project Period (FY)
  1993
- Research Category
  
  Grant-in-Aid for Scientific Research on Priority Areas
- Research Institution
  Tohoku University
クローン化Kチャンネルの抗不整脈薬開発への応用の研究
- Principal Investigator
  
  TAIRA Norio
- Project Period (FY)
  1993 – 1994
- Research Category
  
  Grant-in-Aid for Developmental Scientific Research (B)
- Research Field
  
  応用薬理学・医療系薬学
- Research Institution
  Tohoku University
カリウムイオンチャネルの分子機構
- Principal Investigator
  
  TAIRA Norio
- Project Period (FY)
  1987 – 1989
- Research Category
  
  Grant-in-Aid for General Scientific Research (A)
- Research Field
  
  General pharmacology
- Research Institution
  Tohoku University

All 2017 2016 2015 2014 2013 2012 2011 2010 2007 2005 2004 2003 Other

All Journal Article Presentation Other

[Journal Article] ERK5 induces ankrd1 for catecholamine biosynthesis and homeostasis in adrenal medullary cells2016
- Author(s)
  小原　祐太郎、長澤　隆介、根本　亙、Michael J. Pellegrino、高橋　麻穂、Beth A. Habecker、Philip J.S. Stork、一柳　統、伊藤　裕美、冨田　善彦、石井　邦明、中畑　則道
- Journal Title
  
  Cellular Signalling
  
  Volume: 28 Issue: 3 Pages: 177-189
- DOI
  10.1016/j.cellsig.2015.12.016
- Peer Reviewed / Acknowledgement Compliant / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-15K07963, KAKENHI-PROJECT-26670118
[Journal Article] Phosphorylation of ERK5 on Thr732 is associated with ERK5 nuclear localization and ERK5-dependent transcription.2015
- Author(s)
  本多　拓人、小原　祐太郎、山内　新、 Anthony D. Couvillon、 Justin J. Mason、石井　邦明、中畑　則道
- Journal Title
  
  PLoS ONE
  
  Volume: 10 Issue: 2 Pages: e0117914-e0117914
- DOI
  10.1371/journal.pone.0117914
- Peer Reviewed / Acknowledgement Compliant / Open Access
- Data Source
  KAKENHI-PROJECT-24790063, KAKENHI-PROJECT-26670118
[Journal Article] Is PIP2 involved in the insulin effect?2014
- Author(s)
  石井　邦明、Minghua Wu、小原　祐太郎
- Journal Title
  
  Channels
  
  Volume: 8 Issue: 5 Pages: 391-392
- DOI
  10.4161/19336950.2014.948758
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-24790063, KAKENHI-PROJECT-26670118
[Journal Article] Imaging intraorganellar Ca2+ at subcellular resolution using CEPIA.2014
- Author(s)
  Suzuki, J., Kanemaru, K., Ishii, K., Ohkura, M., Okubo, Y., and Iino, M.
- Journal Title
  
  Nat. Commun.
  
  Volume: 5 Issue: 1 Pages: 4153-4153
- DOI
  10.1038/ncomms5153
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PLANNED-25117002, KAKENHI-PROJECT-25221304, KAKENHI-PROJECT-26670118
[Journal Article] Insulin suppresses IKs (KCNQ1/KCNE1) currents, which require β-subunit KCNE1.2013
- Author(s)
  呉　明華、小原　祐太郎、野呂田　郁夫、永澤　悦伸、石井　邦明
- Journal Title
  
  Pflugers Archiv - Eur J Physiol
  
  Volume: - Issue: 5 Pages: 937-946
- DOI
  10.1007/s00424-013-1352-7
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-24790063, KAKENHI-PROJECT-26670118
[Journal Article] Is a Novel <i>SCN3B</i> Mutation Commonly Found in <i>SCN5A</i>-Negative Brugada Syndrome Patients?2013
- Author(s)
  Kurakami K, Ishii K.
- Journal Title
  
  Circ J
  
  Volume: 77 Issue: 4 Pages: 900-901
- DOI
  10.1253/circj.CJ-13-0242
- NAID
  10031138988
- ISSN
  1346-9843, 1347-4820
- Language
  English
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-22590235
[Journal Article] G_<αh>/transglutaminase-2 activity is required for maximal activatio of adenylylcyclase 8 in human and rat g(n) lioma cells2013
- Author(s)
  Obara Y, Yanagihata Y, Abe T, Dafik L, Ishii K, Nakahata N.
- Journal Title
  
  Cell Signal
  
  Volume: 25 Issue: 3 Pages: 589-597
- DOI
  10.1016/j.cellsig.2012.11.021
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-22590235, KAKENHI-PROJECT-24790063
[Journal Article] Endocytic Regulation of Voltage-Dependent Potassium Channels in the Heart2012
- Author(s)
  Ishii K, Norota I, Obara Y.
- Journal Title
  
  J Pharmacol Sci
  
  Volume: 120 Issue: 4 Pages: 264-269
- DOI
  10.1254/jphs.12R12CP
- NAID
  10031147574
- ISSN
  1347-8613, 1347-8648
- Language
  English
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-22590235
[Journal Article] 電気的リモデリングに対するベプリジルの作用2010
- Author(s)
  石井邦明
- Journal Title
  
  心電図
  
  Volume: 30 Pages: 142-142
- NAID
  10027704736
- Data Source
  KAKENHI-PROJECT-22590235
[Journal Article] Selective inhibition by wortmannin of the increase in Ca^<2+> sensitivity induced by crosstalk of endothelin-1 with norepinephrine in canine ventricular myocardium.2007
- Author(s)
  Chu, L., Norton, I., Ishii, K., Endoh, M.
- Journal Title
  
  Br.J.Pharmacol. (in preparation)
- Description
  「研究成果報告書概要(欧文)」より
- Data Source
  KAKENHI-PROJECT-16390064
[Journal Article] Selective inhibition by wortmannin of the increase in Ca^<2+> sensitivity induced by crosstalk of endothelin-1 with norepinephrine in canine ventricular myocardium.2007
- Author(s)
  Chu, L., Norota, I., Yomogida, S., Ishii, K., Endoh, M.
- Journal Title
  
  Am.J.Physiol. (in preparation)
- Description
  「研究成果報告書概要(欧文)」より
- Data Source
  KAKENHI-PROJECT-16390064
[Journal Article] Cross-talk between β_1-adrenoceptors and ET_A receptors in modulation of the slow component of delayed rectifier K^+ currents.2005
- Author(s)
  Lin, C., Nagai, M., Ishigaki, D.Hayakawa, K., Endoh, M., Ishii, K.
- Journal Title
  
  Naunyn-Schmiedeberg's Arch.Pharmacol. 371
  
  Pages: 133-140
- Description
  「研究成果報告書概要(欧文)」より
- Data Source
  KAKENHI-PROJECT-16390064
[Journal Article] Differential inotropic effects of endothelin-1, angiotensin II, and phenylephrine induced by crosstalk with cAMP-mediated signaling process in dog ventricular myocardium.2004
- Author(s)
  Chu, L., Norota, I., Yomogida, S., Ishii, K., Endoh, M.
- Journal Title
  
  J.Pharmacol.Sci. 96
  
  Pages: 199-207
- NAID
  10014166837
- Description
  「研究成果報告書概要(欧文)」より
- Data Source
  KAKENHI-PROJECT-16390064
[Journal Article] Differential inhibition by TAK-044 of the inotorpic effects of endothelin-1 and endothelin-3.2004
- Author(s)
  Yomogida, S., Maruya, J., Norota, I., Ishii, K., Endoh, M.
- Journal Title
  
  Eur.J.Pharmacol. 492
  
  Pages: 217-224
- Description
  「研究成果報告書概要(欧文)」より
- Data Source
  KAKENHI-PROJECT-16390064
[Journal Article] Dissociation of E-4031 from the HERG channel caused by mutations of an amino acid results in greater block at high stimulation frequency.2003
- Author(s)
  Ishii, K.
- Journal Title
  
  Cardiovasc. Res. 57
  
  Pages: 651-659
- Description
  「研究成果報告書概要(和文)」より
- Data Source
  KAKENHI-PROJECT-14370028
[Journal Article] Dissociation of E-4031 from the HERG channel caused by mutations of an amino acid results in greater block at high stimulation frequency.2003
- Author(s)
  Ishii, K.et al.
- Journal Title
  
  Cardiovasc Res vol.57
  
  Pages: 651-659
- Description
  「研究成果報告書概要(欧文)」より
- Data Source
  KAKENHI-PROJECT-14370028
[Journal Article] Dissociation of E-4031 from the BERG channel caused by mutations of an amino acid results in greater block at high stimulation frequency.2003
- Author(s)
  Ishii, K.
- Journal Title
  
  Cardiovasc.Res. 57
  
  Pages: 651-659
- Data Source
  KAKENHI-PROJECT-14370028
[Presentation] Roles of ERK5 in ion channel expression in PC12 cells2017
- Author(s)
  Kashino Y, Obara Y, Ishii K
- Organizer
  第90回日本薬理学会年会
- Place of Presentation
  長崎ブリックホール（長崎県長崎市）
- Year and Date
  2017-03-16
- Data Source
  KAKENHI-PROJECT-26670118
[Presentation] ラット肺静脈心筋細胞における過分極活性型Cl-チャネルの薬理学的研究2016
- Author(s)
  岡本洋介，石井邦明
- Organizer
  第67回日本薬理学会北部会
- Place of Presentation
  北海道大学（北海道札幌市）
- Year and Date
  2016-09-30
- Data Source
  KAKENHI-PROJECT-26670118
[Presentation] Intra-organellar Ca2+ signaling imaged using genetically encoded Ca2+ indicators2016
- Author(s)
  Suzuki J, Kanamaru K, Ishii K, Ohkura M, Ohkubo Y, Iino M
- Organizer
  第89回日本薬理学会年会
- Place of Presentation
  パシフィコ横浜（神奈川県横浜市）
- Year and Date
  2016-03-11
- Data Source
  KAKENHI-PROJECT-26670118
[Presentation] Impact of hyper polarization-activated Cl- current on arrhythmogenecity of rat pulmonary vein cardiomyocytes2016
- Author(s)
  Okamoto Y, Ono K, Takano M, Ishii K
- Organizer
  第89回日本薬理学会年会
- Place of Presentation
  パシフィコ横浜（神奈川県横浜市）
- Year and Date
  2016-03-09
- Data Source
  KAKENHI-PROJECT-26670118
[Presentation] Effects of high glucose on Kv1.5 and Kir2.1 channels2016
- Author(s)
  Jimbu R, Nagasawa Y, Ishii K
- Organizer
  第89回日本薬理学会年会
- Place of Presentation
  パシフィコ横浜（神奈川県横浜市）
- Year and Date
  2016-03-10
- Data Source
  KAKENHI-PROJECT-26670118
[Presentation] ラット肺静脈心筋細胞における過分極活性型Cl-チャネルの分子生物学的研究2016
- Author(s)
  岡本洋介，石井邦明
- Organizer
  第26回日本循環薬理学会
- Place of Presentation
  信州大学（長野県松本市）
- Year and Date
  2016-12-02
- Data Source
  KAKENHI-PROJECT-26670118
[Presentation] 肺動脈血管平滑筋細胞に発現する内因性のCav1.2はアゼルニジピンにより量的修飾を受ける2016
- Author(s)
  那須史明，倉上和也，小原祐太郎，石井邦明
- Organizer
  第67回日本薬理学会北部会
- Place of Presentation
  北海道大学（北海道札幌市）
- Year and Date
  2016-09-30
- Data Source
  KAKENHI-PROJECT-26670118
[Presentation] 神経細胞におけるMidnolinの生理的•病理的な役割について．2015
- Author(s)
  今井　亨，小原祐太郎，佐藤秀則，加藤丈夫，石井邦明
- Organizer
  第66回日本薬理学会北部会
- Place of Presentation
  富山国際会議場（富山県富山市）
- Year and Date
  2015-09-18
- Data Source
  KAKENHI-PROJECT-26670118
[Presentation] Cav1.2はアゼルニジピンにより量的修飾をうける．2015
- Author(s)
  那須史明，倉上和也，小原祐太郎，石井邦明
- Organizer
  第66回日本薬理学会北部会
- Place of Presentation
  富山国際会議場（富山県富山市）
- Year and Date
  2015-09-18
- Data Source
  KAKENHI-PROJECT-26670118
[Presentation] タンパク質型Ca2+インジケーターCEPIAを用いた小胞体・ミトコンドリア内腔Ca2+動態の可視化と機能解析2015
- Author(s)
  鈴木純二、金丸和典、石井邦明、大倉正道、大久保洋平、飯野正光
- Organizer
  第88回日本薬理学会年会
- Place of Presentation
  名古屋国際会議場（名古屋市熱田区）
- Year and Date
  2015-03-18
- Data Source
  KAKENHI-PROJECT-26670118
[Presentation] アゼルニジピンはCav1.2チャネルの細胞膜発現量を減少させる2015
- Author(s)
  那須史明、倉上和也、石井邦明
- Organizer
  第88回日本薬理学会年会
- Place of Presentation
  名古屋国際会議場（名古屋市熱田区）
- Year and Date
  2015-03-20
- Data Source
  KAKENHI-PROJECT-26670118
[Presentation] Azelnidipine reduces cell-surface expression of Cav1.2 channel．2015
- Author(s)
  Nasu F, Kurakami K, Ishii K
- Organizer
  第30回日本不整脈学会学術大会・第32回日本心電学会学術集会
- Place of Presentation
  国立京都国際会館（京都府京都市）
- Year and Date
  2015-07-29
- Data Source
  KAKENHI-PROJECT-26670118
[Presentation] ERK5とERK1/2のクロストーク機構について2014
- Author(s)
  小原祐太郎、本田拓人、山内　新、Couvillon Anthony、Mason Justin、石井邦明、中畑則道
- Organizer
  第65回日本薬理学会北部会
- Place of Presentation
  コラッセふくしま（福島市）
- Year and Date
  2014-09-27
- Data Source
  KAKENHI-PROJECT-26670118
[Presentation] アゼルニジピンがCav1.2チャネルを量的に修飾する可能性について2014
- Author(s)
  那須史明、倉上和也、石井邦明
- Organizer
  第24回日本循環薬理学会
- Place of Presentation
  山形テルサ（山形市）
- Year and Date
  2014-12-05
- Data Source
  KAKENHI-PROJECT-26670118
[Presentation] Internalization of KCNQ1 by activation of the α1 adrenergic receptor2014
- Author(s)
  倉上和也、野呂田郁夫、那須史明、永澤悦伸、小原祐太郎、石井邦明
- Organizer
  第31回日本心電学会学術集会
- Place of Presentation
  ザ・プリンスパークタワー東京（東京都港区）
- Year and Date
  2014-07-25
- Data Source
  KAKENHI-PROJECT-26670118
[Presentation] アゼルニジピンがCav1.2チャネルをインターナリゼーションする可能性について2014
- Author(s)
  那須史明、倉上和也、石井邦明
- Organizer
  第65回日本薬理学会北部会
- Place of Presentation
  コラッセふくしま（福島市）
- Year and Date
  2014-09-26
- Data Source
  KAKENHI-PROJECT-26670118
[Presentation] Gq蛋白共役型受容体によるQ1/E1チャネルのエンドサイトーシス2012
- Author(s)
  石井邦明
- Organizer
  日本心電学会学術集会
- Place of Presentation
  千葉（幕張メッセ）
- Data Source
  KAKENHI-PROJECT-22590235
[Presentation] アンジオテンシン受容体 1型および α_<1A>受容体刺激による KCNQ1のインターナリゼーション機構2012
- Author(s)
  石井邦明
- Organizer
  第22回日本循環薬理学会
- Place of Presentation
  富山(富山国際会議場)
- Year and Date
  2012-11-30
- Data Source
  KAKENHI-PROJECT-22590235
[Presentation] Gq蛋白共役型受容体による Q1/E1チャネルのエンドサイトーシス2012
- Author(s)
  石井邦明
- Organizer
  第29回日本心電学会学術集会
- Place of Presentation
  千葉(幕張メッセ国際会議場)
- Year and Date
  2012-10-13
- Data Source
  KAKENHI-PROJECT-22590235
[Presentation] インスリンによるKCNQ1/KCNE1電流の抑制と増大2011
- Author(s)
  石井邦明, 他
- Organizer
  日本循環薬理学会
- Place of Presentation
  岡山(岡山大学50周年記念館)
- Year and Date
  2011-12-02
- Data Source
  KAKENHI-PROJECT-22590235
[Presentation] Ix_8チャネルの修飾機構:質的修飾と量的修飾2010
- Author(s)
  石井邦明
- Organizer
  日本心電学会学術集会
- Place of Presentation
  大分
- Year and Date
  2010-10-09
- Data Source
  KAKENHI-PROJECT-22590235
[Presentation] I_<Ks>チャネルの修飾機構 :質的修飾と量的修飾2010
- Author(s)
  石井邦明
- Organizer
  第27回日本心電学会学術集会
- Place of Presentation
  大分(iichiko総合文化センター)
- Year and Date
  2010-10-09
- Data Source
  KAKENHI-PROJECT-22590235
[]

1. NUNOKI Kazuo (10172743)

# of Collaborated Projects: 8 results

# of Collaborated Products: 0 results
2. ENDOH Masao (40004668)

# of Collaborated Projects: 7 results

# of Collaborated Products: 5 results
3. YOMOGIDA Shinichi (90250802)

# of Collaborated Projects: 5 results

# of Collaborated Products: 3 results
4. TAIRA Norio (60004553)

# of Collaborated Projects: 3 results

# of Collaborated Products: 0 results
5. HOSOYA Yukio (10250945)

# of Collaborated Projects: 3 results

# of Collaborated Products: 0 results
6. YANAGISAWA Teruyuki (90133941)

# of Collaborated Projects: 2 results

# of Collaborated Products: 0 results
7. ABE Takaaki (80292209)

# of Collaborated Projects: 2 results

# of Collaborated Products: 0 results
8. YAMAZAKI Yoshihiko (10361247)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
9. YAWO Hiromu (00144353)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
10. UMEMIYA Masashi (50271911)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
11. KAWA Kazuyoshi (70125839)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
12. SAHEKI Shuichi (80145078)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
13. YOMOGIDA Shin-ichi (90292440)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
14. NISHIMARU Kazuhide (60361250)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
15. 渡邉建彦 (70028356)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
16. 大津浩 (60250742)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
17. 蔦川修生 (00551855)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
18. 永澤悦伸 (40513057)

# of Collaborated Projects: 1 results

# of Collaborated Products: 2 results
19. 佐藤慶祐 (50125564)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
20. 飯島俊彦 (30004724)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
21. 石幡明 (40232326)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
22. 小原祐太郎 (40400270)

# of Collaborated Projects: 1 results

# of Collaborated Products: 4 results
23. 中島修 (80312841)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
24. 佐々木雅幸

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
25. ICHIYANAGI Osamu

# of Collaborated Projects: 0 results

# of Collaborated Products: 1 results
26. KANEMARU Kazunori

# of Collaborated Projects: 0 results

# of Collaborated Products: 1 results
27. STORK Philip

# of Collaborated Projects: 0 results

# of Collaborated Products: 1 results
28. HABECKER Beth

# of Collaborated Projects: 0 results

# of Collaborated Products: 1 results
29. 大久保洋平

# of Collaborated Projects: 0 results

# of Collaborated Products: 1 results
30. 飯野正光

# of Collaborated Projects: 0 results

# of Collaborated Products: 1 results

ISHII KUNIAKI 石井 邦明

ISHII Kuniaki 石井 邦明

石井 邦明 イシイ クニアキ

Research Projects

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Co-Researchers

Pathophysiological significance of decreased K channel expression by receptor activationPrincipal Investigator

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Imaging of quantitative changes in surface expression of ion channels using isolated perfused heartsPrincipal Investigator

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Endocytosis of human K channel by receptor activation and its intracellular mechanismsPrincipal Investigator

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Identification of the activation gate of HERG K^+ channelPrincipal Investigator

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Molecular mechanisms of the slow deactivation of HERG channelPrincipal Investigator

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Involvement of tyrosine kinase in regulation of ion channel functions and crosstalk between signal transduction systemsPrincipal Investigator

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致死的不整脈原因遺伝子の発現系の確立とその抗不整脈薬への応用Principal Investigator

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ISHII KUNIAKI 石井邦明

ISHII Kuniaki 石井邦明

石井邦明イシイクニアキ