Yamashita Katsumi 山下克美

… Alternative Names

YAMASHITA Katsumi 山下克美

山下克美ヤマシタカツミ

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Researcher Number	10191280
Other IDs
External Links
Affiliation (based on the past Project Information) *help	2015 – 2017: 金沢大学, 薬学系, 准教授 2010: 金沢大学, 薬学系, 准教授 2004: Kanazawa Univ., Grad.Sch.Nat.Sci.& Tech., Associate Professor, 自然科学研究科, 助教授 1991: 九州大学, 大学院・医学系研究科, 助教授 1991: 九州大学, 大学院医学系研究科, 助教授 1990: 九州大学, 大学院・医学系研究科, 助手 1988 – 1989: 九州大学, 大学院医学系研究科, 助手
Review Section/Research Field	Principal Investigator 分子細胞生物学 / Functional biochemistry Except Principal Investigator Functional biochemistry / Risk sciences of radiation/Chemicals / Molecular biology
Keywords	Principal Investigator MPF / cdc2キナ-ゼ / タンパク質脱リン酸化酵素 / cdc25タンパク質 / 細胞周期 / オカダ酵 / カリクリンA / オカダ酸 / 間接螢光抗体法 / サイクリンA … More / サイクリンB1 / cdc2 / +5BN4b2 / G1期 / G1 / S / 温度感受性変異株 / tsBN462 / G^1 / サイクリン / ヒストンH1キナ-ゼ / タンパク質安定化 / リン酸化 / 脱リン酸化 / タンパク質分解 / プロテインホスファターセ / Cdc25A / Cdc25B / プロテインホスファターゼ / ユビキチン化 … More Except Principal Investigator 細胞周期 / RCC1遺伝子 / BN2変異 / CCG1遺伝子 / 点突然変異 / ストレス / シグナル伝達 / 蛋白分解 / 蛋白質分解 / G1期 / G2期 / 核タンパク質 / 染色体凝縮 / 卵母細胞 / 温度感受性変異 / PCC / DNA損傷 / ヌクレオチド除去修復 / 紫外線 / シクロブタン型ピリミジンダイマー / (6-4)光産物 / 色素性乾皮症 / ノックアウトマウス / 適応応答 / モノクローナル抗体 / DNA damage / nucleotide excision repair / ultraviolet light / cyclobutane pyrimidine dimer / (6-4) photoproduct / xeroderma pigmentosum / knock-out mouse / adaptive response / テロメア / DNA複製 / 相同性DNA組換え / リボソームDNA / CST複合体 / rDNA / 複製フォーク停止 / DNA相同組換え / 遺伝的不安定性 / 遺伝学 / stn1 / 温度感受性株 / 複製フォーク / サブテロメア / 塩基除去修復 / ８オキソグアニン Less

Identification of the responsible PPase that stabilyze cell cycle regulator Cdc25BPrincipal Investigator
- Principal Investigator
  
  Yamashita Katsumi
- Project Period (FY)
  2015 – 2017
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Research Field
  
  Functional biochemistry
- Research Institution
  Kanazawa University
Transactions of telomere components
- Principal Investigator
  
  Ishikawa Fuyuki
- Project Period (FY)
  2015 – 2017
- Research Category
  
  Grant-in-Aid for Scientific Research (A)
- Research Field
  
  Molecular biology
- Research Institution
  Kyoto University
Study for degradation mechanism of a cell cycle regulator induced by Stress-activated MAP kinases
- Principal Investigator
  
  UCHIDA Sanae
- Project Period (FY)
  2008 – 2010
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Research Field
  
  Functional biochemistry
- Research Institution
  Kanazawa University
Analysis of a novel back-up repair system for UV-induced DNA damage in human cells.
- Principal Investigator
  
  MATSUNAGA Tsukasa
- Project Period (FY)
  2003 – 2004
- Research Category
  
  Grant-in-Aid for Scientific Research (B)
- Research Field
  
  Risk sciences of radiation/Chemicals
- Research Institution
  Kanazawa University, Graduate School of Natural Science and Technology
cdd2キナ-ゼの活性制御に関与するフォスファタ-ゼの研究Principal Investigator
- Principal Investigator
  
  山下克美
- Project Period (FY)
  1991
- Research Category
  
  Grant-in-Aid for Cancer Research
- Research Institution
  Kyushu University
MDFの活性化に働くcdc25蛋白質の発現と活性の制御に関する研究Principal Investigator
- Principal Investigator
  
  山下克美
- Project Period (FY)
  1991
- Research Category
  
  Grant-in-Aid for Scientific Research on Priority Areas
- Research Institution
  Kyushu University
A型およびB型サイクリンの細胞周期における発現と活性の調節Principal Investigator
- Principal Investigator
  
  関口猛, 山下克美
- Project Period (FY)
  1991 – 1992
- Research Category
  
  Grant-in-Aid for General Scientific Research (C)
- Research Field
  
  分子細胞生物学
- Research Institution
  Kyushu University
MPFの活性化機構Principal Investigator
- Principal Investigator
  
  山下克美
- Project Period (FY)
  1990
- Research Category
  
  Grant-in-Aid for Scientific Research on Priority Areas
- Research Institution
  Kyushu University
細胞増殖の調節(特にG1期とG2期で)に関与するヒト遺伝子のクロ-ニング
- Principal Investigator
  
  西本毅治
- Project Period (FY)
  1989
- Research Category
  
  Grant-in-Aid for Scientific Research on Priority Areas
- Research Institution
  Kyushu University
細胞増殖の調節(特にG1期とG2期で)に関与するヒト遺伝子のクローニング
- Principal Investigator
  
  西本毅治
- Project Period (FY)
  1988
- Research Category
  
  Grant-in-Aid for Scientific Research on Priority Areas
- Research Institution
  Kyushu University

All 2010 2009 2008 2004

All Journal Article Presentation Patent

[Journal Article] The extracellular signal-regulated kinase-mitogen-activated protein kinase pathway phosphorylates and targets Cdc25A for SCF^<βTrCP>-dependent degradation for cell cycle arrest.2009
- Author(s)
  Isoda, M., Kanemori, Y., Nakajo, N., Uchida, S., Yamashita, K., Ueno, H., Sagata, N.
- Journal Title
  
  Molecular and Cellular Biology 20
  
  Pages: 2186-2195
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-20570126
[Journal Article] Stress-activated mitogen-activated protein kinase c-Jun NH_2-terminal kinase and p38 target Cdc25B for degradation.2009
- Author(s)
  Uchida, S., Yoshioka, K., Kizu, R., Nakagama, H., Matsunaga, T., Ishizaka, Y., Poon, R., Y., Yamashita, K.
- Journal Title
  
  Cancer Research 69
  
  Pages: 6438-6444
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-20570126
[Journal Article] Nuclear export signal in CDC25B.2004
- Author(s)
  Uchida, S., Ohtsubo, M., Shimura, M., Hirata, M., Nakagama, H., Matsunaga, T., Yoshida, M., Ishizaka, Y., Yamashita, K.
- Journal Title
  
  Biochem.Biophys.Res.Commun. 316
  
  Pages: 226-232
- Description
  「研究成果報告書概要(欧文)」より
- Data Source
  KAKENHI-PROJECT-15310036
[Journal Article] Binding of 14-3-3beta but not 14-3-3sigma controls the cytoplasmic localization of CDC25B : binding site preferences of 14-3-3 subtypes and the subcellular localization of CDC25B.2004
- Author(s)
  Uchida, S., Kuma, A., Ohtsubo, M., Shimura, M., Hirata, M., Nakagama, H., Matsunaga, T., Ishizaka, Y., Yamashita K.
- Journal Title
  
  J.Cell Sci. 117
  
  Pages: 3011-3020
- Description
  「研究成果報告書概要(欧文)」より
- Data Source
  KAKENHI-PROJECT-15310036
[Patent] Cdc25BとβTrCPとの特異的結合を利用した検出系2008
- Inventor(s)
  山下克美, 内田早苗
- Industrial Property Rights Holder
  金沢大学
- Patent Publication Number
  2010-124818
- Filing Date
  2008-12-01
- Data Source
  KAKENHI-PROJECT-20570126
[Patent] Cdc25Bとβ-TrCPとの特異的結合を利用した検出系2008
- Inventor(s)
  山下克美, 内田早苗
- Industrial Property Rights Holder
  金沢大学
- Industrial Property Number
  2008-306804
- Filing Date
  2008-12-01
- Data Source
  KAKENHI-PROJECT-20570126
[Presentation] 環境発がん物質による細胞周期制御因子Cdc25の分解機構2010
- Author(s)
  山下克美
- Organizer
  日本環境変異原学会第39回大会
- Place of Presentation
  つくば国際会議場(茨城県)
- Year and Date
  2010-11-16
- Data Source
  KAKENHI-PROJECT-20570126
[Presentation] Application of bioimaging to detect genotoxic and non-genotoxic carcinogens.2009
- Author(s)
  山下克美
- Organizer
  第68回日本癌学会学術総会
- Place of Presentation
  パシフィコ横浜(神奈川県)
- Year and Date
  2009-10-03
- Data Source
  KAKENHI-PROJECT-20570126
[Presentation] Application of bioimaging to detect genotoxic and non-genotoxic carcinogens2009
- Author(s)
  山下克美
- Organizer
  第68回日本癌学会学術総会
- Place of Presentation
  パシフィコ横浜 (神奈川県)
- Year and Date
  2009-10-01
- Data Source
  KAKENHI-PROJECT-20570126
[Presentation] CDK活性化フォスフアターゼCdc25の機能制御機構2008
- Author(s)
  山下克美
- Organizer
  第31回日本分子生物学会年会・第81回日本生化学会大会合同大会
- Place of Presentation
  神戸
- Year and Date
  2008-12-11
- Data Source
  KAKENHI-PROJECT-20570126
[Presentation] CDK活性化フォスファターゼCdc25の機能制御機構2008
- Author(s)
  山下克美
- Organizer
  第31回日本分子生物学会年会・第81回日本生化学会大会合同大会
- Place of Presentation
  神戸ポートアイランド(兵庫県)
- Year and Date
  2008-12-11
- Data Source
  KAKENHI-PROJECT-20570126
[Presentation] JNK-and SCF^<βTrCP>-mediated destruction of Cdc25B controls cell cycle arrest by non-genotoxic stress.2008
- Author(s)
  山下克美
- Organizer
  8^<th> International Conference on Protein Phosphatase
- Place of Presentation
  前橋テルサ(群馬県)
- Year and Date
  2008-11-12
- Data Source
  KAKENHI-PROJECT-20570126
[Presentation] JNK and SCF^<β-TrCP>-mediated destruction of Cdc258 controls cell cycle arrest by non-genotoxic stress2008
- Author(s)
  山下克美
- Organizer
  8th Internat ional Conference on Protein Phosphatases
- Place of Presentation
  前橋
- Year and Date
  2008-11-12
- Data Source
  KAKENHI-PROJECT-20570126

1. 関口猛 (60187846)

# of Collaborated Projects: 3 results

# of Collaborated Products: 0 results
2. 西本毅治 (10037426)

# of Collaborated Projects: 2 results

# of Collaborated Products: 0 results
3. UCHIDA Sanae (50464045)

# of Collaborated Projects: 1 results

# of Collaborated Products: 2 results
4. KUDO Yasusei (50314753)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
5. MATSUNAGA Tsukasa (60192340)

# of Collaborated Projects: 1 results

# of Collaborated Products: 2 results
6. ISHIGAKI Yasuhito (20232275)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
7. WAKASUGI Mitsuo (80345595)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
8. MOCHISDA Satoru (60590304)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
9. SHIMA Hiroshi (10196462)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
10. Ishikawa Fuyuki (30184493)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
11. 宇澤聡 (30232812)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
12. 若林雄一 (40303119)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
13. 藤芳暁 (70371705)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
14. YOSHIOKA Katsuji

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results

Yamashita Katsumi 山下 克美

YAMASHITA Katsumi 山下 克美

山下 克美 ヤマシタ カツミ

Research Projects

Research Products

Co-Researchers

Identification of the responsible PPase that stabilyze cell cycle regulator Cdc25BPrincipal Investigator

Principal Investigator

Project Period (FY)

Research Category

Research Field

Research Institution

Transactions of telomere components

Principal Investigator

Project Period (FY)

Research Category

Research Field

Research Institution

Study for degradation mechanism of a cell cycle regulator induced by Stress-activated MAP kinases

Principal Investigator

Project Period (FY)

Research Category

Research Field

Research Institution

Analysis of a novel back-up repair system for UV-induced DNA damage in human cells.

Principal Investigator

Project Period (FY)

Research Category

Research Field

Research Institution

cdd2キナ-ゼの活性制御に関与するフォスファタ-ゼの研究Principal Investigator

Principal Investigator

Project Period (FY)

Research Category

Research Institution

MDFの活性化に働くcdc25蛋白質の発現と活性の制御に関する研究Principal Investigator

Principal Investigator

Project Period (FY)

Research Category

Research Institution

A型およびB型サイクリンの細胞周期における発現と活性の調節Principal Investigator

Principal Investigator

Project Period (FY)

Research Category

Research Field

Research Institution

MPFの活性化機構Principal Investigator

Principal Investigator

Project Period (FY)

Research Category

Research Institution

細胞増殖の調節(特にG1期とG2期で)に関与するヒト遺伝子のクロ-ニング

Principal Investigator

Project Period (FY)

Research Category

Research Institution

細胞増殖の調節(特にG1期とG2期で)に関与するヒト遺伝子のクローニング

Principal Investigator

Project Period (FY)

Research Category

Research Institution

[Journal Article] The extracellular signal-regulated kinase-mitogen-activated protein kinase pathway phosphorylates and targets Cdc25A for SCF^<βTrCP>-dependent degradation for cell cycle arrest.2009

Author(s)

Journal Title

Data Source

[Journal Article] Stress-activated mitogen-activated protein kinase c-Jun NH_2-terminal kinase and p38 target Cdc25B for degradation.2009

Author(s)

Journal Title

Data Source

[Journal Article] Nuclear export signal in CDC25B.2004

Author(s)

Journal Title

Description

Data Source

[Journal Article] Binding of 14-3-3beta but not 14-3-3sigma controls the cytoplasmic localization of CDC25B : binding site preferences of 14-3-3 subtypes and the subcellular localization of CDC25B.2004

Author(s)

Journal Title

Description

Data Source

[Patent] Cdc25BとβTrCPとの特異的結合を利用した検出系2008

Yamashita Katsumi 山下克美

YAMASHITA Katsumi 山下克美

山下克美ヤマシタカツミ