Akira OOTSUYAMA 大津山彰

… Alternative Names

OOTSUYAMA Akira 大津山彰

大津山彰オオツヤマアキラ

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Researcher Number	10194218
Other IDs
Affiliation (based on the past Project Information) *help	2018 – 2023: 産業医科大学, 医学部, 准教授 2013: 産業医科大学, 医学部, 教育教授 2011 – 2013: 産業医科大学, 医学部, 准教授 2007 – 2008: University of Occupational and Environmental Health, Japan, School of Med., Assoc. Prof. 2003 – 2006: 産業医科大学, 医学部, 助教授 … More 1997 – 2000: University of Occupational and Environmental Health, School of Medicine, Associate Professor, 医学部, 助教授 1998: 広島大学, 産業医科大学・医学部, 助教授 1996: 産業医科大学, 医学部, 講師 1991 – 1992: 国立がんセンター研究所, 放射線研究部, 研究員 Less
Review Section/Research Field	Principal Investigator 環境影響評価(含放射線生物学) / Risk sciences of radiation/Chemicals / Basic Section 63020:Radiation influence-related / 放射線5生物学 Except Principal Investigator Risk sciences of radiation/Chemicals / 環境影響評価(含放射線生物学) / Basic Section 31010:Nuclear engineering-related
Keywords	Principal Investigator Fas / ガンマ線 / 反復照射 / ベータ線 / 骨髄障害 / 放射線 / 放射線障害回避 / 放射線障害 / 幹細胞移植 / 組織再生 … More / 再生医療 / 放射線骨髄障害 / ADSC / 脂肪幹細胞 / radiation carcinogenesis / skin cancer / repetitive irradiation / Beta-irradiation / KO mouse / P53 gene / 放射線発がん / 皮膚がん / ノックアウトマウス / p53遺伝子 / time course / transgenic mouse / HITEC mouse / organ-specific / gamma-rays / Radiation-induced / New HITEC マウス / 経時変化 / トランスジェニックマウス / New HITECマウス / 臓器特異性 / 放射線誘発突然変異 / Apoptosis / T cell / thymus / spleen / gamma rays / gld mice / lpr mice / FAS / 1prマウス / アポトーシス / T細胞 / 胸腺 / 脾臓 / gldマウス / lprマウス / 突然変異 / 放射線誘発損傷 / 部分肝切除 / in vivo / HITECマウス / ベ-タ線 / 低線量 / 皮膚癌 / 閾値 / マウス … More Except Principal Investigator アポトーシス / p53 / 放射線 / tissue repair / dose-rate dependence / p53 gene / 組織修復 / 線量率 / p53遺伝子 / 放射線被曝 / 遺伝子変異 / 低線量率ひばく / LOH解析 / 発がん高感受性モデルマウス / 低線量率被ばく / トリチウム / genomic instability / radiation / p53-dependent apoptosis / mutation / ゲノム不安定性 / 突然変異 / p53-deficient mouse / X-rays / malformation / apoptosis / p53ノックアウトマウス / p53ノックスとマウス / 奇形 / 遺伝的不安定性 / 免疫能低下 / 遺伝子不安定性 / p５３ / T細胞 / 若年時被曝 / 炎症 / NF-κB / 若年時放射線被曝 / T cell receptor / 遅延型突然変異 / トランスジェニックスマウス / 自然交配 / 受精卵移植 / HITECマウス / rpsL遺伝子 / 体細胞突然変異 / トランスジェニックマウス / scidマウス Less

Evaluation of Ecological Effects of Tritium Using Carcinogenesis Highly Susceptible Mouse Models
- Principal Investigator
  
  Umata Toshiyuki
- Project Period (FY)
  2020 – 2023
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Review Section
  
  Basic Section 31010:Nuclear engineering-related
- Research Institution
  University of Occupational and Environmental Health, Japan
Verification of avoidance of radiation-induced acute injury by adipose stem cell (ADSC) transplantation -Focus on bone marrow damage-Principal Investigator
- Principal Investigator
  
  Akira OOTSUYAMA
- Project Period (FY)
  2018 – 2020
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Review Section
  
  Basic Section 63020:Radiation influence-related
- Research Institution
  University of Occupational and Environmental Health, Japan
An analysis of the mechanisms of loss of immune system in T cell induced by p53 gene instability after irradiation at a young age
- Principal Investigator
  
  OKAZAKI Ryuji
- Project Period (FY)
  2011 – 2013
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Research Field
  
  Risk sciences of radiation/Chemicals
- Research Institution
  University of Occupational and Environmental Health, Japan
The analysis of the dysfunction of p53 in delayed mutation
- Principal Investigator
  
  OKAZAKI Ryuji
- Project Period (FY)
  2007 – 2008
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Research Field
  
  Risk sciences of radiation/Chemicals
- Research Institution
  University of Occupational and Environmental Health, Japan
生体内の機能細胞における放射線誘発DNA損傷・突然変異の蓄積の有無に関する検証Principal Investigator
- Principal Investigator
  
  大津山彰
- Project Period (FY)
  2005 – 2006
- Research Category
  
  Grant-in-Aid for Exploratory Research
- Research Field
  
  Risk sciences of radiation/Chemicals
- Research Institution
  University of Occupational and Environmental Health, Japan
Infulence of p53 on the induction of mouse skin tumors by repetitive beta-irradiationPrincipal Investigator
- Principal Investigator
  
  OOTSUYAMA Akira
- Project Period (FY)
  2004 – 2007
- Research Category
  
  Grant-in-Aid for Scientific Research (B)
- Research Field
  
  Risk sciences of radiation/Chemicals
- Research Institution
  University of Occupational and Environmental Health, Japan
The role of p53 in protection of radiation mutagenesis
- Principal Investigator
  
  NORIMURA Toshiyuki
- Project Period (FY)
  2003 – 2005
- Research Category
  
  Grant-in-Aid for Scientific Research (A)
- Research Field
  
  Risk sciences of radiation/Chemicals
- Research Institution
  University of Occupational and Environmental Health, Japan
Analysis of tissue-specific mutations induced by radiation in HITEC micePrincipal Investigator
- Principal Investigator
  
  OOTSUYAMA Akira
- Project Period (FY)
  1999 – 2000
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Research Field
  
  環境影響評価(含放射線生物学)
- Research Institution
  University of Occupational & Environmental Health
放射線高感受性トランスジェニックマウスを用いた鋭敏な突然変異検出系の開発
- Principal Investigator
  
  鈴木文男
- Project Period (FY)
  1998 – 1999
- Research Category
  
  Grant-in-Aid for Exploratory Research
- Research Field
  
  環境影響評価(含放射線生物学)
- Research Institution
  Hiroshima University
Biological defense mechanisms against teratogenic damage and the role of p53 gene
- Principal Investigator
  
  NORIMURA Toshiyuki
- Project Period (FY)
  1997 – 1999
- Research Category
  
  Grant-in-Aid for Scientific Research (B)
- Research Field
  
  環境影響評価(含放射線生物学)
- Research Institution
  University of Occupational and Environmental Health
Relationship between retardation of auto immune diseasePrincipal Investigator
- Principal Investigator
  
  OOTSUYAMA Akira
- Project Period (FY)
  1996 – 1997
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Research Field
  
  環境影響評価(含放射線生物学)
- Research Institution
  University of Occupational and Environmental Health
低線量放射線の発癌閾値の検証Principal Investigator
- Principal Investigator
  
  大津山彰
- Project Period (FY)
  1991 – 1992
- Research Category
  
  Grant-in-Aid for General Scientific Research (C)
- Research Field
  
  放射線5生物学
- Research Institution
  National Cancer Center Research Institute and Research Center for Innovative Oncology, National Cancer Center Hospital East

[Journal Article] Long Bones Exhibit Adaptive Responses to Chronic Low‐Dose‐Rate Ionizing Radiation despite its Lifespan‐Shortening and Carcinogenic Effects on <scp>C57BL</scp> /6 Mice2022
- Author(s)
  Kohzaki Masaoki、Ootsuyama Akira、Abe Toshiaki、Tsukamoto Manabu、Umata Toshiyuki、Okazaki Ryuji
- Journal Title
  
  JBMR Plus
  
  Volume: 6 Issue: 12 Pages: 1-13
- DOI
  10.1002/jbm4.10688
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-20K05386, KAKENHI-PROJECT-20K12172, KAKENHI-PROJECT-19K18513
[Journal Article] Life-Prolonging Effects of Adipose Tissue-Derived Stem Cell Transplantation into Mice Exposed to a Lethal Dose of X-Rays2021
- Author(s)
  Akira Ootsuyama
- Journal Title
  
  Journal of UOEH
  
  Volume: 43 Issue: 1 Pages: 25-31
- DOI
  10.7888/juoeh.43.25
- NAID
  130007995226
- ISSN
  0387-821X, 2187-2864
- Year and Date
  2021-03-01
- Language
  English
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-18K11649
[Journal Article] Comparison of the fertility of tumor suppressor gene-deficient C57BL/6 mouse strains reveals stable reproductive aging and novel pleiotropic gene2021
- Author(s)
  Kohzaki Masaoki、Ootsuyama Akira、Umata Toshiyuki、Okazaki Ryuji
- Journal Title
  
  Scientific Reports
  
  Volume: 11 Issue: 1 Pages: 12357-12369
- DOI
  10.1038/s41598-021-91342-9
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-20K05386, KAKENHI-PROJECT-20K12172
[Journal Article] The p53 dependent delayed effects of radiation varied at the timing of irradiation in p53+/- mice2014
- Author(s)
  Okazaki R, Ootsuyama A
- Journal Title
  
  J Radiat Res
  
  Volume: 55 Issue: 1 Pages: 25-31
- DOI
  10.1093/jrr/rrt083
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-23510070
[Journal Article] The p53 dependent delayed effects of radiation varied at the timing of irradiation in p53^<+/-> mice2014
- Author(s)
  Okazaki R, Ootsuyama A
- Journal Title
  
  J Radiat Res (Tokyo)
  
  Volume: 55(1) Pages: 25-31
- Data Source
  KAKENHI-PROJECT-23510070
[Journal Article] Establishment of MSP for the mouse p53 gene2011
- Author(s)
  Okazaki R, Ootsuyama A, Yoshida Y, Norimura T
- Journal Title
  
  Molecular Biology International
  
  Volume: 2011 Pages: 938435-938435
- DOI
  10.4061/2011/938435
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-23510070
[Journal Article] 郡山市内医師と一般市民の福島第一原発事故後の放射線に対する意識の違い（アンケート調査結果から）2011
- Author(s)
  岡崎龍史、大津山彰、阿部利明、久保達彦、太神和廣、菊池辰夫、菊池信太郎、佐久間秀人
- Journal Title
  
  福島県医師会報
  
  Volume: 73 Pages: 38-41
- Data Source
  KAKENHI-PROJECT-23510070
[Journal Article] 老化のトピックスーテロメア、ミトコンドリア、p532009
- Author(s)
  岡崎龍史、大津山彰、法村俊之
- Journal Title
  
  放射線生物学研究 (in press)
- NAID
  40016736305
- Data Source
  KAKENHI-PROJECT-19510061
[Journal Article] Induction of mouse skin tumors by repetitive beta-irradiation : influence of a p53 gene.2007
- Author(s)
  Akira OOTSUYAMA
- Journal Title
  
  The 51th Annual Meeting of the Japan Radiation Research SocIety, Makuhari, Chiba.
- Description
  「研究成果報告書概要(欧文)」より
- Data Source
  KAKENHI-PROJECT-16310046
[Journal Article] Induction of skin cancer by repeated beta-irradiation : A role of p53 gene.2007
- Author(s)
  Akira OOTSUYAMA
- Journal Title
  
  The 144th Annual Meting of Japanese Society of Veterinaly Science, Ebetsu, kkaido.
- Description
  「研究成果報告書概要(欧文)」より
- Data Source
  KAKENHI-PROJECT-16310046
[Journal Article] Influence of p53 on the induction of mouse skin tumors by repetitive beta-irradiation.2007
- Author(s)
  Aklra OOTSUYAMA
- Journal Title
  
  1 3th International Congress of Radiation Research, San Francisco, USA.
- Description
  「研究成果報告書概要(欧文)」より
- Data Source
  KAKENHI-PROJECT-16310046
[Journal Article] The delayed manifestation of T-cell receptor (TCR) variants in X-irradiated mice depends on Trp53 status.2006
- Author(s)
  Igari, K., Igari, Y., Okazaki, R., Kato, F., Ootsuyama, A., Norimura, T.
- Journal Title
  
  Radiation Research (in press)
- Description
  「研究成果報告書概要(欧文)」より
- Data Source
  KAKENHI-PROJECT-15201013
[Journal Article] Role of p53 gene in genetic instability induced by ionizing radiation.2005
- Author(s)
  Igari, K., Igari, Y., Kakihara, H., Kato, F., Ootsuyama, A., Norimura, T.
- Journal Title
  
  International Congress Series 1276
  
  Pages: 262-263
- Description
  「研究成果報告書概要(欧文)」より
- Data Source
  KAKENHI-PROJECT-15201013
[Journal Article] Increased radiosensitivity of splenic T lymphocytes in pregnant mice.2005
- Author(s)
  Igari, Y., Igari, K., Kakihara, H., Kato, F., Ootsuyama, A., Norimura, T.
- Journal Title
  
  International Congress Series 1276
  
  Pages: 183-184
- NAID
  130005443068
- Description
  「研究成果報告書概要(欧文)」より
- Data Source
  KAKENHI-PROJECT-15201013
[Journal Article] Detection of radiation-induced mutations in the liver after partial hepatectomy using HITEC transgenic mice2005
- Author(s)
  A.OOTSUYAMA
- Journal Title
  
  International Congress Series 1276
  
  Pages: 260-261
- Data Source
  KAKENHI-PROJECT-15201013
[Journal Article] Radioadaptive response for protection against radiation-induced teratogenesis.2005
- Author(s)
  Okazaki, R., Ootsuyama, A., Norimura, T.
- Journal Title
  
  Radiation Research 163(3)
  
  Pages: 266-270
- Description
  「研究成果報告書概要(欧文)」より
- Data Source
  KAKENHI-PROJECT-15201013
[Journal Article] Effect of exposure to low-dose rate radiation on autoimmune diseases of immunologically suppressed MRL/MpTn-gld/gld mice.2003
- Author(s)
  Ootsuyama, A., Okazaki, R., Norimura, T.
- Journal Title
  
  J.Radiation Research 44(3)
  
  Pages: 243-247
- Description
  「研究成果報告書概要(欧文)」より
- Data Source
  KAKENHI-PROJECT-15201013
[Journal Article] Effect of exposure to low-dose rate radiation on autoimmune diseases of immunologically suppressed MRL/MpTn-gld/gld mice2003
- Author(s)
  A.OOTSUYAMA
- Journal Title
  
  J. Radiation Research 44・3
  
  Pages: 243-247
- Description
  「研究成果報告書概要(和文)」より
- Data Source
  KAKENHI-PROJECT-15201013
[Presentation] Risk assessment of carcinogenesis due to exposure to tritiated water using a highly sensitive mouse model of carcinogenesis2024
- Author(s)
  Toshiyuki Umata, Akira Ootsuyama, Megumi Sasatani
- Organizer
  The 5th Workshop of the Research Center for Radiation Hazards and Medical Science
- Invited
- Data Source
  KAKENHI-PROJECT-20K05386
[Presentation] Tritium water induces small intestinal tumors in Min mice2023
- Author(s)
  Toshiyuki Umata, Akira Ootsuyama, Megumi Sasatani
- Organizer
  日本放射線影響学会第66回大会
- Data Source
  KAKENHI-PROJECT-20K05386
[Presentation] Analysis of tritium-induced gastrointestinal tumors in Min mouse2022
- Author(s)
  馬田敏幸, 大津山彰
- Organizer
  日本放射線影響学会第65回大会
- Data Source
  KAKENHI-PROJECT-20K05386
[Presentation] Minマウスを用いたトリチウム誘発小腸がんの解析2021
- Author(s)
  馬田敏幸、大津山彰、笹谷めぐみ
- Organizer
  第64回日本放射線影響学会
- Data Source
  KAKENHI-PROJECT-20K05386
[Presentation] Analysis of tritium-induced gastrointestinal tumor in Min mouse2021
- Author(s)
  Toshiyuki Umata, Akira Ootsuyama, Megumi Sasatani
- Organizer
  The 94th Annual Meeting of the Japanese Biochemical Society
- Data Source
  KAKENHI-PROJECT-20K05386
[Presentation] Transplantation of adipose-derived stem cell (ADSCs) plus bone marroe to mice after whole body X-ray-irradiation2020
- Author(s)
  Akira OOTSUYAMA
- Organizer
  日本放射線影響学会　第63回大会 (福島)
- Data Source
  KAKENHI-PROJECT-18K11649
[Presentation] Analysis of tritium-induced gastrointestinal tumor in Min mouse2020
- Author(s)
  Toshiyuki Umata, Akira Ootsuyama, Megumi Sasatani
- Organizer
  第63回日本放射線影響学会
- Data Source
  KAKENHI-PROJECT-20K05386
[Presentation] 発がん高感受性モデルマウスを用いたトリチウム誘発がんの解析2020
- Author(s)
  馬田敏幸，大津山彰，笹谷めぐみ
- Organizer
  第33回バイオメディカル・ファジイ・システム学会
- Data Source
  KAKENHI-PROJECT-20K05386
[Presentation] 脂肪幹細胞(ADSC)による放射線障害の軽減作用　III2019
- Author(s)
  大津山　彰
- Organizer
  第56回　放射線影響懇話会　(熊本)
- Data Source
  KAKENHI-PROJECT-18K11649
[Presentation] Effect of adipose-derived stem cell (ADSC) transplantation to reduce whole body X ray damage in mice2019
- Author(s)
  Akira OOTSUYAMA
- Organizer
  16th International Congress of Radiation Research (Manchester, England)
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-18K11649
[Presentation] Effects of adipose tissue-derived stem cell transplantation in whole-body X-ray irradiated mice -Destination of transplantrd cells-2019
- Author(s)
  Akira OOTSUYAMA
- Organizer
  日本放射線影響学会　第62回大会 (京都)
- Data Source
  KAKENHI-PROJECT-18K11649
[Presentation] X線被ばくマウスに対する脂肪組織由来幹細胞(ADSC)移植の放射線障害軽減効果2018
- Author(s)
  大津山　彰
- Organizer
  日本放射線影響学会　第61回大会
- Data Source
  KAKENHI-PROJECT-18K11649
[Presentation] 脂肪幹細胞(ADSC)による放射線障害の軽減作用 II2018
- Author(s)
  大津山　彰
- Organizer
  第55回放射線影響懇話会
- Data Source
  KAKENHI-PROJECT-18K11649
[Presentation] Pig-A 遺伝子をリポーターとして用いたin vitro突然変異検出試験の高線量被曝環境作業者の健康影響評価応用への検討2013
- Author(s)
  大津山彰、岡﨑龍史、猪狩和之
- Organizer
  第31回産業医科大学学会総会
- Place of Presentation
  北九州
- Year and Date
  2013-10-26
- Data Source
  KAKENHI-PROJECT-23510070
[Presentation] 福島県内外の一般市民および医師の福島第一原子力発電所事故後の放射線被曝に対する意識調査2013
- Author(s)
  岡﨑龍史、大津山彰、阿部利明、久保達彦
- Organizer
  日本放射線影響学会第56回大会
- Place of Presentation
  ホテルクラウンパレス青森、青森
- Data Source
  KAKENHI-PROJECT-23510070
[Presentation] Irradiation of mice at a young age induces immune modulation of spleen cells in old age2013
- Author(s)
  Okazaki R, Song Y, Yoshida Y, Kanazawa T, Ootsuyama A.
- Organizer
  59th Annual Radiation Research Meeting
- Place of Presentation
  Hilton New Orleans Riverside Hotel, New Orleans, USA
- Data Source
  KAKENHI-PROJECT-23510070
[Presentation] Irradiation of mice at a young age induces immune modulation of spleen cells in old age2013
- Author(s)
  Okazaki R, Song Y, Yoshida Y, Kanazawa T, Ootsuyama A
- Organizer
  59th Annual Radiation Research Meeting
- Place of Presentation
  New Orleans, USA
- Data Source
  KAKENHI-PROJECT-23510070
[Presentation] 低線量放射線照射後のメタボローム解析と血算の変動2013
- Author(s)
  岡﨑龍史、大津山彰、鈴木光浩
- Organizer
  第50回放射線影響懇話会
- Place of Presentation
  佐賀
- Year and Date
  2013-07-27
- Data Source
  KAKENHI-PROJECT-23510070
[Presentation] The differences in delayed mutations of the p53 gene after irradiation at the various ages2012
- Author(s)
  Okazaki R, Ootsuyama A
- Organizer
  58th Annual Radiation Research Meeting
- Place of Presentation
  Rio Mar Resort and Spa (San Juan, Puerto Rico)
- Data Source
  KAKENHI-PROJECT-23510070
[Presentation] 照射週齢の違いによる遅延型突然変異におけるp53遺伝子の解析2011
- Author(s)
  岡崎龍史、大津山彰
- Organizer
  第54回放射線影響学会
- Place of Presentation
  神戸商工会議所会館 (神戸)
- Data Source
  KAKENHI-PROJECT-23510070
[Presentation] 一般向け緊急被曝ガイド2011
- Author(s)
  岡崎龍史、大津山彰
- Organizer
  第48回放射線影響懇話会
- Place of Presentation
  くまもと県民交流館パレア（熊本）
- Data Source
  KAKENHI-PROJECT-23510070
[Presentation] Dynamic expression of p53 after irradiation2011
- Author(s)
  Ootsuyama A, Okazaki R, Norimura T
- Organizer
  14th International Congress of Radiation Research
- Place of Presentation
  Palace of Culture and Science (Poland)
- Data Source
  KAKENHI-PROJECT-23510070
[Presentation] Dynamics of Delayed p53 Mutation after Irradiation2011
- Author(s)
  Okazaki R, Ootsuyama A, et al.
- Organizer
  14th International Congress of Radiation Research
- Place of Presentation
  Palace of Culture and Science (Poland)
- Data Source
  KAKENHI-PROJECT-23510070
[Presentation] The analysis of p53 sequence in delayed mutation2009
- Author(s)
  Okazaki R, Ootsuyama A, Mabuchi Y, Suzuki S, Matsuzaki Y, Norimura T.
- Organizer
  2nd Asian Congress of Radiation Research
- Place of Presentation
  Seoul
- Data Source
  KAKENHI-PROJECT-19510061
[Presentation] 放射線による発がん過程を変えるp53遺伝子の存在状態2008
- Author(s)
  大津山彰、岡崎龍史、法村俊之
- Organizer
  第51回放射線影響学会
- Place of Presentation
  北九州
- Data Source
  KAKENHI-PROJECT-19510061
[Presentation] 遅延型突然変異におけるp53遺伝子の解析2008
- Author(s)
  岡崎龍史、大津山彰、法村俊之
- Organizer
  第51回放射線影響学会
- Place of Presentation
  北九州
- Data Source
  KAKENHI-PROJECT-19510061
[Presentation] 遅延型突然変異におけるp53遺伝子配列の解析2008
- Author(s)
  岡崎龍史, 大津山彰, 法村俊之
- Organizer
  第51回放射線影響学会
- Place of Presentation
  北九州
- Year and Date
  2008-11-20
- Data Source
  KAKENHI-PROJECT-19510061
[Presentation] Influence of p53 on the induction of mouse skin tumors by repetitive beta-irradiation2007
- Author(s)
  Ootsuyama A, Okazaki R, Norimura T.
- Organizer
  13th international congress of radiation research
- Place of Presentation
  San Francisco
- Data Source
  KAKENHI-PROJECT-19510061
[Presentation] Influence of p53 on the induction of mouse skin tumors by repetitive beta-irradiation2007
- Author(s)
  Akira OOTSUYAMA
- Organizer
  13th International Congress of Radiation Research
- Place of Presentation
  San Francisco,USA
- Year and Date
  2007-07-10
- Data Source
  KAKENHI-PROJECT-16310046
[Presentation] 放射線による発がんの発生率と発生時期はp53遺伝子の存在状態に依存する2007
- Author(s)
  大津山彰
- Organizer
  第144回日本獣医学会
- Place of Presentation
  北海道江別市
- Year and Date
  2007-09-02
- Description
  「研究成果報告書概要(和文)」より
- Data Source
  KAKENHI-PROJECT-16310046
[Presentation] TP53 and TP53-related genes associated with protection from apoptosis in the radio-adaptive response2007
- Author(s)
  Okazaki R, Ootsuyama A, Norimura T.
- Organizer
  13th international congress of radiation research,
- Place of Presentation
  San Francisco
- Data Source
  KAKENHI-PROJECT-19510061
[Presentation] 放射線による発がん率と発生時期はp53遺伝子の存在状態に依存する2007
- Author(s)
  大津山彰、岡崎龍史、法村俊之
- Organizer
  第144回日本獣医学会学術集会(日本実験動物医学会)
- Place of Presentation
  北海道
- Data Source
  KAKENHI-PROJECT-19510061
[Presentation] Induction and persistence of T-cell receptor (TCR) variants in X-irradiated mice depends on p53 status2007
- Author(s)
  Norimura T, Kakihara H, Igari K, Okazaki R, Ootsuyama A.
- Organizer
  13th international congress of radiation research
- Place of Presentation
  San Francisco
- Data Source
  KAKENHI-PROJECT-19510061
[Presentation] β線による皮膚発がんの発生率と発生時期はp53遺伝子の存在状態に依存2007
- Author(s)
  大津山彰
- Organizer
  第50回日本放射線影響学会
- Place of Presentation
  千葉県幕張市
- Year and Date
  2007-11-15
- Description
  「研究成果報告書概要(和文)」より
- Data Source
  KAKENHI-PROJECT-16310046
[Presentation] lnfluence of p530 on the induction of mouse skin tumors by repetitive beta-lrradlatlon.2007
- Author(s)
  Akira OOTSUYAMA
- Organizer
  13th lnternational Congress of Radiation Research
- Place of Presentation
  San Frandsco USA
- Year and Date
  2007-07-10
- Description
  「研究成果報告書概要(欧文)」より
- Data Source
  KAKENHI-PROJECT-16310046
[Presentation] 放射線被曝による遅延型突然変異におけるp53遺伝子の解析2007
- Author(s)
  岡崎龍史、猪狩和之、柿原ひろ代、大津山彰、法村俊之
- Organizer
  第25回産業医科大学学会
- Place of Presentation
  北九州
- Year and Date
  2007-10-05
- Data Source
  KAKENHI-PROJECT-19510061
[Presentation] lnduction of mouse skin tumors by repetitive beta-lrradiation : lnffuence of a p53 gene.2007
- Author(s)
  Akira OOTSUYAMA
- Organizer
  The 51st Annual Meeting of the Japan Radlation Research Sodety
- Place of Presentation
  Makuhari, Chiba
- Year and Date
  2007-11-15
- Description
  「研究成果報告書概要(欧文)」より
- Data Source
  KAKENHI-PROJECT-16310046
[Presentation] Influence of p53 on the induction of mouse skin tumors by repetitive beta-irradiation2007
- Author(s)
  Akira OOTSUYAMA
- Organizer
  13th.International Congress of Radiation Research
- Place of Presentation
  San Francisco,USA
- Year and Date
  2007-07-10
- Description
  「研究成果報告書概要(和文)」より
- Data Source
  KAKENHI-PROJECT-16310046
[Presentation] lnduction of skin cancer by repeated beta-irradiation : A role of p53 gene2007
- Author(s)
  Akira OOTSUYAMA
- Organizer
  The 144th Annual Metlng of Japanese Society of Veterlnaly Science
- Place of Presentation
  Ebetsu, Hokkaido
- Year and Date
  2007-09-02
- Description
  「研究成果報告書概要(欧文)」より
- Data Source
  KAKENHI-PROJECT-16310046
[Presentation] 遅延型突然変異におけるp53遺伝子配列の解析2007
- Author(s)
  岡崎龍史、大津山彰、法村俊之
- Organizer
  第50回放射線影響学会
- Place of Presentation
  千葉
- Data Source
  KAKENHI-PROJECT-19510061
[Presentation] β線による皮膚発がんの発生率と発生時期はp53遺伝子の存在状態に依存2007
- Author(s)
  大津山彰、岡崎龍史、法村俊之
- Organizer
  第50回放射線影響学会
- Place of Presentation
  千葉
- Data Source
  KAKENHI-PROJECT-19510061
[Presentation] Pig-A遺伝子をリポーターとして用いたin vitro突然変異検出試験の高線量被曝環境作業者の健康影響評価応用への検討
- Author(s)
  大津山彰、岡﨑龍史、猪狩和之
- Organizer
  第31回産業医科大学学会総会
- Place of Presentation
  産業医科大学ラマティーニホール、北九州
- Data Source
  KAKENHI-PROJECT-23510070
[Presentation] 低線量放射線照射後のメタボローム解析と血算の変動
- Author(s)
  岡﨑龍史、大津山彰、鈴木光浩
- Organizer
  第50回放射線影響懇話会
- Place of Presentation
  佐賀大学臨床小講堂、佐賀
- Data Source
  KAKENHI-PROJECT-23510070

1. NORIMURA Toshiyuki (20039530)

# of Collaborated Projects: 5 results

# of Collaborated Products: 5 results
2. OKAZAKI Ryuji (50309960)

# of Collaborated Projects: 3 results

# of Collaborated Products: 23 results
3. KATO Fumio (20309959)

# of Collaborated Projects: 3 results

# of Collaborated Products: 3 results
4. NOMOTO Satoshi (90258608)

# of Collaborated Projects: 2 results

# of Collaborated Products: 0 results
5. YOSHIDA Yasuhiro (10309958)

# of Collaborated Projects: 1 results

# of Collaborated Products: 3 results
6. FUJIKAWA Kazuo (90247958)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
7. KUNUGITA Naoki (90178020)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
8. Umata Toshiyuki (30213482)

# of Collaborated Projects: 1 results

# of Collaborated Products: 9 results
9. 田ノ岡宏 (90076969)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
10. 鈴木文男 (10019672)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results

Akira OOTSUYAMA 大津山 彰

OOTSUYAMA Akira 大津山 彰

大津山 彰 オオツヤマ アキラ

Research Projects

Research Products

Co-Researchers

Evaluation of Ecological Effects of Tritium Using Carcinogenesis Highly Susceptible Mouse Models

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Verification of avoidance of radiation-induced acute injury by adipose stem cell (ADSC) transplantation -Focus on bone marrow damage-Principal Investigator

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An analysis of the mechanisms of loss of immune system in T cell induced by p53 gene instability after irradiation at a young age

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The analysis of the dysfunction of p53 in delayed mutation

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生体内の機能細胞における放射線誘発DNA損傷・突然変異の蓄積の有無に関する検証Principal Investigator

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Infulence of p53 on the induction of mouse skin tumors by repetitive beta-irradiationPrincipal Investigator

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The role of p53 in protection of radiation mutagenesis

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Analysis of tissue-specific mutations induced by radiation in HITEC micePrincipal Investigator

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放射線高感受性トランスジェニックマウスを用いた鋭敏な突然変異検出系の開発

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Biological defense mechanisms against teratogenic damage and the role of p53 gene

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Relationship between retardation of auto immune diseasePrincipal Investigator

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低線量放射線の発癌閾値の検証Principal Investigator

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[Journal Article] Long Bones Exhibit Adaptive Responses to Chronic Low‐Dose‐Rate Ionizing Radiation despite its Lifespan‐Shortening and Carcinogenic Effects on <scp>C57BL</scp> /6 Mice2022

Author(s)

Akira OOTSUYAMA 大津山彰

OOTSUYAMA Akira 大津山彰

大津山彰オオツヤマアキラ