Ishikawa Tomohisa 石川智久

… Alternative Names

ISHIKAWA Tomohisa 石川智久

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Researcher Number	10201914
Other IDs
External Links
Affiliation (Current)	2025: 静岡県立大学, 薬学部, 教授
Affiliation (based on the past Project Information) *help	2015 – 2024: 静岡県立大学, 薬学部, 教授 2006 – 2013: 静岡県立大学, 薬学部, 教授 2010: 静岡県立大学, 薬学部, 助教 2005: 静岡県立大学, 薬学部, 助教授 1998 – 2002: 静岡県立大学, 薬学部, 助教授 1998: University of Tsukuba, Institute of Basic Medical Sciences, Assistant Professor 1995 – 1997: 筑波大学, 基礎医学系, 講師
Review Section/Research Field	Principal Investigator Medium-sized Section 59:Sports sciences, physical education, health sciences, and related fields / Basic Section 59040:Nutrition science and health science-related / Applied health science / General pharmacology / General physiology / General pharmacology / Medical pharmacy / Biological pharmacy Except Principal Investigator Basic Section 59040:Nutrition science and health science-related / 応用薬理学・医療系薬学 … More / Applied health science / Biological pharmacy / Circulatory organs internal medicine / General pharmacology Less
Keywords	Principal Investigator DAF-2 / Ca^<2+> / NO / β細胞 / 膵β細胞 / 肝線維化 / NASH / インスリン分泌 / β-cells / インスリン … More / 糖尿病 / シグナル伝達 / 非侵襲的診断 / 揮発性有機化合物 / MASH / 非アルコール性脂肪肝炎 / 肝星細胞 / メラトニン / N-アセチルセロトニン / メラトニン受容体 / glucose / NO synthase / rat / グルコース / NO合成酵素 / ラット / ランゲルハンス氏島 / 過酸化水素 / 薬理学 / アポトーシス / パッチクランプ / 冠動脈 / 液-液相分離 / マウス / ガスクロマトグラフィー / 呼気分析 / 治療薬スクリーニング / 線維化 / 構造活性相関 / DIF-1 / 妊娠糖尿病 / N‐アセチルセロトニン / 膵β細胞量 / 新生 / β 細胞 / 増殖 / ジアシルグリセロール / ジアシルグリセロールキナーゼ / セロトニン / Anontosis / Hydrogen peroxide / Insulin secretion / TRP / Hyposmolarity / Signal transduction / Pharmacology / カルシウムイオン / カチオンチャネル / 低浸透圧刺激 / 伸展刺激 / 膵臓β細胞 / TRPチャネル / 低浸透圧 / islet of Langerhans / cGMP / α細胞 / Islets of Langerhans / NOC 7 / 薬学 / アネキシンV / IP_3受容体 / ストア作動性カルシウム流入 / 酸化ストレス / ミトコンドリア / カルシウム / モルモット / 内皮由来過分極因子 / カリウムチャネル / 内皮細胞 / ウサギ / サイクリックGMP / サイクリックAMP / 平滑筋細胞 / カリウムチャンネル … More Except Principal Investigator 糖尿病 / ジアシルグリセロールキナーゼ / インスリン分泌 / 膵β細胞 / ジアシルグリセロール / シグナル伝達 / mechanotransduction / Rho / メカノトランスダクション / CGRP / SB209670 / 細胞増殖 / 脂質 / 糖脂肪毒性 / インスリン / metabolic syndrome / pharmacology / mechanostress / glucose metabolism / skeletal muscle / exercise / cell signaling / 生理学 / メタボリックシンドローム / 薬理学 / ストレス / 糖代謝 / 骨格筋 / エクササイズ / phosphorylation / Rho kinase / protein kinase C / tyrosine kinase / integrin / myogenic response / blood vessel / イメージング解析 / 循環調節機構 / 筋原性収縮反応 / cSrc ファミリー / メカノセンサー / タンパクチロシンリン酸化 / 血行力学受容 / Rho-kinase / 細胞内シグナリング / チロシンリン酸化 / イメージング / インテグリン / チロシンキナーゼ / 低分子GTP結合タンパク / プロテインキナーゼC / リン酸化 / 血行力学受容・応答 / ion channel / feedback / excitation / mechanical contraction / arrhythmia / cardiac hypertrophy / heart failure / 自立神経 / フィードバック / 電気的興奮 / 機械的収縮 / 分子循環器病学 / 不整脈 / イオンチャンネル / 心肥大 / 心不全 / capsaicin / CO2 / sensory nerve / askeletal muscle / hindlimb / regional blood flow / ラット / EDHF / 血管弛緩 / 血流 / 二酸化炭素 / カルシトニン遺伝子関連ペプチド / カプサイシン / CO2分圧 / 知覚神経 / 骨格筋運動 / ラット後肢 / 局所血流 / Astrocytes / ET_B receptor / Endothelin / cold injury / 増殖因子 / 脳抽出液 / 中枢神経系 / アンタゴニスト / 脊髄損傷 / 凍結損傷 / エンドセリン受容体 / アストロサイト / ET_B受容体 / エンドセリン Less

ヒト呼気中揮発性有機物の構成解析に基づく肝線維化簡易診断法の確立に向けた基盤研究Principal Investigator
- Principal Investigator
  
  石川智久
- Project Period (FY)
  2024 – 2026
- Research Category
  
  Grant-in-Aid for Challenging Research (Exploratory)
- Review Section
  
  Medium-sized Section 59:Sports sciences, physical education, health sciences, and related fields
- Research Institution
  University of Shizuoka
肝星細胞における液－液相分離を標的としたNASH進行スイッチ制御の確立Principal Investigator
- Principal Investigator
  
  石川智久
- Project Period (FY)
  2023 – 2025
- Research Category
  
  Grant-in-Aid for Scientific Research (B)
- Review Section
  
  Basic Section 59040:Nutrition science and health science-related
- Research Institution
  University of Shizuoka
肥満誘発β細胞代償性増殖ブレーキの解除を活用した脂質分子による血糖調節戦略の構築
- Principal Investigator
  
  金子雪子
- Project Period (FY)
  2023 – 2025
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Review Section
  
  Basic Section 59040:Nutrition science and health science-related
- Research Institution
  University of Shizuoka
Development of non-invasive assessment method for NASH using expired gas analysis with AI-powered gas chromatographyPrincipal Investigator
- Principal Investigator
  
  Ishikawa Tomohisa
- Project Period (FY)
  2021 – 2023
- Research Category
  
  Grant-in-Aid for Challenging Research (Exploratory)
- Review Section
  
  Medium-sized Section 59:Sports sciences, physical education, health sciences, and related fields
- Research Institution
  University of Shizuoka
Establishment of novel therapeutic strategies for diabetes by increasing pancreatic beta-cell mass through targeting of intracellular lipid signaling
- Principal Investigator
  
  KANEKO Yukiko
- Project Period (FY)
  2020 – 2022
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Review Section
  
  Basic Section 59040:Nutrition science and health science-related
- Research Institution
  University of Shizuoka
Basic study for developing NASH therapeutic drugs by using a small molecule derived from the cellular slime mold serving as a lead compoundPrincipal Investigator
- Principal Investigator
  
  ISHIKAWA Tomohisa
- Project Period (FY)
  2020 – 2022
- Research Category
  
  Grant-in-Aid for Scientific Research (B)
- Review Section
  
  Basic Section 59040:Nutrition science and health science-related
- Research Institution
  University of Shizuoka
Development of disease model in mice on the basis of mechanisms for pathogenesis of gestational diabetes.Principal Investigator
- Principal Investigator
  
  Ishikawa Tomohisa
- Project Period (FY)
  2018 – 2020
- Research Category
  
  Grant-in-Aid for Challenging Research (Exploratory)
- Review Section
  
  Medium-sized Section 59:Sports sciences, physical education, health sciences, and related fields
- Research Institution
  University of Shizuoka
Involvement of DAG metabolism in beta-cell dysfunction during type 2 diabetes
- Principal Investigator
  
  Kaneko Yukiko
- Project Period (FY)
  2017 – 2019
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Research Field
  
  Applied health science
- Research Institution
  University of Shizuoka
Intracellular lipid signaling analysis for the development of novel diabetes therapeutic agents targeting neogenesis and proliferation of pancreatic beta-cellsPrincipal Investigator
- Principal Investigator
  
  Ishikawa Tomohisa
- Project Period (FY)
  2017 – 2019
- Research Category
  
  Grant-in-Aid for Scientific Research (B)
- Research Field
  
  Applied health science
- Research Institution
  University of Shizuoka
Possible involvement of gut-derived melatonin as a negative regulator of insulin secretionPrincipal Investigator
- Principal Investigator
  
  Ishikawa Tomohisa
- Project Period (FY)
  2015 – 2017
- Research Category
  
  Grant-in-Aid for Challenging Exploratory Research
- Research Field
  
  Applied health science
- Research Institution
  University of Shizuoka
Role of crosstalk between peripheral circadian clock and NO-cGMP system of pancreatic beta-cells in the pathogenesis of diabetesPrincipal Investigator
- Principal Investigator
  
  ISHIKAWA Tomohisa
- Project Period (FY)
  2011 – 2013
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Research Field
  
  Medical pharmacy
- Research Institution
  University of Shizuoka
Intermolecular network involved in calcium-dependent apoptosis of pancreatic beta-cells and possible targets for diabetes treatmentPrincipal Investigator
- Principal Investigator
  
  ISHIKAWA Tomohisa
- Project Period (FY)
  2008 – 2010
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Research Field
  
  Biological pharmacy
- Research Institution
  University of Shizuoka
Molecular mechanisms for regulation of glucose metabolism in skeletal muscle cells by biomechanical stress.
- Principal Investigator
  
  NAKAYAMA Koichi
- Project Period (FY)
  2006 – 2007
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Research Field
  
  Biological pharmacy
- Research Institution
  Iwate Medical University
  University of Shizuoka
Roles of TRP channels in response to exposure with high concentrations of glucose in pancreatic β cellsPrincipal Investigator
- Principal Investigator
  
  ISHIKAWA Tomohisa
- Project Period (FY)
  2005 – 2007
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Research Field
  
  General pharmacology
- Research Institution
  University of Shizuoka
Physiological role of NO produced by constitutive NO synthase in pancreatic islet of LangerhansPrincipal Investigator
- Principal Investigator
  
  ISHIKAWA Tomohisa
- Project Period (FY)
  2001 – 2002
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Research Field
  
  General pharmacology
- Research Institution
  University of Shizuoka
Realtime imaging analysis of tyrosine phosphorylation in response to hemodynamic forces
- Principal Investigator
  
  NAKAYAMA Koichi
- Project Period (FY)
  2000 – 2002
- Research Category
  
  Grant-in-Aid for Scientific Research (B)
- Research Field
  
  応用薬理学・医療系薬学
- Research Institution
  University of Shizuoka
Analysis of intracellular mechanisms contributing to insulin secretion from pancreatic β-cellsPrincipal Investigator
- Principal Investigator
  
  ISHIKAWA Tomohisa
- Project Period (FY)
  1999 – 2000
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Research Field
  
  General pharmacology
- Research Institution
  University of Shizuoka
内皮由来過分極因子の作用メカニズムの解明Principal Investigator
- Principal Investigator
  
  石川智久
- Project Period (FY)
  1997 – 1998
- Research Category
  
  Grant-in-Aid for Encouragement of Young Scientists (A)
- Research Field
  
  General physiology
- Research Institution
  University of Shizuoka
  University of Tsukuba
Contraction-excitation feedback in heart failure and cardiac hypertrophy
- Principal Investigator
  
  YAMAGUCHI Iwao
- Project Period (FY)
  1997 – 1998
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Research Field
  
  Circulatory organs internal medicine
- Research Institution
  University of Tsukuba
血管平滑筋弛緩反応におけるイオンチャンネルの関与Principal Investigator
- Principal Investigator
  
  石川智久
- Project Period (FY)
  1996
- Research Category
  
  Grant-in-Aid for Encouragement of Young Scientists (A)
- Research Field
  
  General physiology
- Research Institution
  University of Tsukuba
The role new pepdidergic neuron in autoregulation of regional blood flow.
- Principal Investigator
  
  GOTO Katsutoshi
- Project Period (FY)
  1996 – 1998
- Research Category
  
  Grant-in-Aid for Scientific Research (B)
- Research Field
  
  General pharmacology
- Research Institution
  University of Tsukuba
Analysis of dedifferentiation and growth of glial cells in tissue regeneration process after brain damage
- Principal Investigator
  
  GOTO Katsutoshi
- Project Period (FY)
  1995 – 1997
- Research Category
  
  Grant-in-Aid for Scientific Research (A)
- Research Field
  
  応用薬理学・医療系薬学
- Research Institution
  University of Tsukuba

[Book] Mechanosensitivity of Pancreaticβ-cells, Adipocytes, and Skeletal Muscle Cells : The Therapeutic Targets of Metabolic Syndrome. Mechanically Gated Channels and their Regulation2012
- Author(s)
  Nakayama K, Tanabe Y, Obara K, Ishikawa T
- Publisher
  Springer
- Data Source
  KAKENHI-PROJECT-23590192
[Book] Mechanosensitivity in Cells and Tissues 3.2010
- Author(s)
  Nakayama K, Obara K, Ishikawa T, Nishizawa S.
- Publisher
  Springer, Dordrecht
- Data Source
  KAKENHI-PROJECT-20590085
[Journal Article] Oral ingestion of Shiikuwasha extract suppresses diabetes progression in db/db mice by preserving β-cell mass2024
- Author(s)
  Kaji Megumi、Kaneko Yukiko K.、Ihim Stella Amarachi、Kanoh Ran、Yamamoto Moe、Yamaguchi Momoka、Ishikawa Tomohisa
- Journal Title
  
  Frontiers in Nutrition
  
  Volume: 10 Pages: 01-09
- DOI
  10.3389/fnut.2023.1336133
- Data Source
  KAKENHI-PROJECT-23K10803
[Journal Article] Enhanced Contraction of Arterial Smooth Muscle Cell in Skin Artery Is Sensitive to Hyperpolarization Mediated by BKCa Channel in Chronic Constriction Injury Model Rat2023
- Author(s)
 Ishida Hirotake、Ishikawa Tomohisa、Saito Shin-ya
- Journal Title
 
 Biological and Pharmaceutical Bulletin
 
 Volume: 46 Issue: 3 Pages: 399-403
- DOI
 10.1248/bpb.b22-00603
- ISSN
 0918-6158, 1347-5215
- Year and Date
 2023-03-01
- Language
 English
- Peer Reviewed
- Data Source
 KAKENHI-PROJECT-20H04110, KAKENHI-PROJECT-21K19727, KAKENHI-PROJECT-23K28004
[Journal Article] GDP-bound Rab27a regulates clathrin disassembly through HSPA8 after insulin secretion2023
- Author(s)
  Soshiro Kodera, Toshihide Kimura, Tomoki Nishioka, Yukiko K Kaneko, Momoka Yamaguchi, Kozo Kaibuchi, Tomohisa Ishikawa
- Journal Title
  
  Arch. Biochem. Biophys.
  
  Volume: 749 Pages: 109789-109789
- DOI
  10.1016/j.abb.2023.109789
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-23K08013, KAKENHI-PROJECT-21K19727, KAKENHI-PROJECT-23K28004
[Journal Article] Apigenin Alleviates Endoplasmic Reticulum Stress-Mediated Apoptosis in INS-1 β-Cells2023
- Author(s)
  Ihim Stella Amarachi、Kaneko Yukiko K.、Yamamoto Moe、Yamaguchi Momoka、Kimura Toshihide、Ishikawa Tomohisa
- Journal Title
  
  Biological and Pharmaceutical Bulletin
  
  Volume: 46 Issue: 4 Pages: 630-635
- DOI
  10.1248/bpb.b22-00913
- ISSN
  0918-6158, 1347-5215
- Year and Date
  2023-04-01
- Language
  English
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-20H04110, KAKENHI-PROJECT-20K08891, KAKENHI-PROJECT-20K11512, KAKENHI-PROJECT-23K08013, KAKENHI-PROJECT-21K19727, KAKENHI-PROJECT-23K28004
[Journal Article] Non-target GC-MS analyses of fecal VOCs in NASH-hepatocellular carcinoma model STAM mice2023
- Author(s)
  Kato Mai、Yamaguchi Momoka、Ooka Akira、Takahashi Ryota、Suzuki Takuji、Onoda Keita、Yoshikawa Yuko、Tsunematsu Yuta、Sato Michio、Yoshioka Yasukiyo、Igarashi Miki、Hayakawa Sumio、Shoji Kumiko、Shoji Yutaka、Ishikawa Tomohisa、Watanabe Kenji、Miyoshi Noriyuki
- Journal Title
  
  Scientific Reports
  
  Volume: 13 Issue: 1 Pages: 8924-8924
- DOI
  10.1038/s41598-023-36091-7
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-22K17781, KAKENHI-PROJECT-22K06665, KAKENHI-PROJECT-22K07078, KAKENHI-PROJECT-22K11757, KAKENHI-PROJECT-21K19727, KAKENHI-ORGANIZER-23H03820, KAKENHI-PLANNED-23H03823, KAKENHI-PROJECT-22H04979, KAKENHI-PROJECT-20H04109, KAKENHI-PROJECT-23K28004
[Journal Article] Increased Tropism of Extracellular Vesicles Derived from Palmitic Acid-Treated Hepatocytes to Activated Hepatic Stellate Cells2022
- Author(s)
  Yamaguchi Momoka、Kanazawa Takanori、Morino Sumire、Iioka Shingo、Watanabe Yuta、Dohi Naoki、Higashi Kenjirou、Kondo Hiromu、Ishikawa Tomohisa
- Journal Title
  
  Membranes
  
  Volume: 12 Issue: 10 Pages: 1023-1023
- DOI
  10.3390/membranes12101023
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-21K06516, KAKENHI-PROJECT-21K19727, KAKENHI-PROJECT-22K17781, KAKENHI-PROJECT-20H04110, KAKENHI-PROJECT-21J15529
[Journal Article] 次世代糖尿病治療標的としての膵β細胞量の制御2022
- Author(s)
  金子雪子、石川智久
- Journal Title
  
  Farumashia
  
  Volume: 58 Issue: 2 Pages: 132-136
- DOI
  10.14894/faruawpsj.58.2_132
- NAID
  130008150146
- ISSN
  0014-8601, 2189-7026
- Language
  Japanese
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-20K11512
[Journal Article] Involvement of Diacylglycerol Kinase on the Regulation of Insulin Secretion in Pancreatic β-Cells during Type 2 Diabetes2022
- Author(s)
  Kaneko Yukiko K.、Sawatani Toshiaki、Ishikawa Tomohisa
- Journal Title
  
  YAKUGAKU ZASSHI
  
  Volume: 142 Issue: 5 Pages: 457-463
- DOI
  10.1248/yakushi.21-00176-2
- ISSN
  0031-6903, 1347-5231
- Year and Date
  2022-05-01
- Language
  Japanese
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-20K11512
[Journal Article] Harmine suppresses collagen production in hepatic stellate cells by inhibiting DYRK1B2022
- Author(s)
  Yamaguchi Momoka、Ohbayashi Saya、Ooka Akira、Yamashita Hinako、Motohashi Nanami、Kaneko Yukiko K.、Kimura Toshihide、Saito Shin-ya、Ishikawa Tomohisa
- Journal Title
  
  Biochemical and Biophysical Research Communications
  
  Volume: 600 Pages: 136-141
- DOI
  10.1016/j.bbrc.2022.02.054
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-19K20186, KAKENHI-PROJECT-20H04110, KAKENHI-PROJECT-20K11512, KAKENHI-PROJECT-22KJ2582, KAKENHI-PROJECT-20K08891
[Journal Article] Nobiletin ameliorates glucose tolerance by protecting against β-cell loss in type-2 diabetic db/db mice2022
- Author(s)
  Kaneko Yukiko K.、Tara Yuki、Ihim Stella Amarachi、Yamamoto Moe、Kaji Megumi、Ishikawa Tomohisa
- Journal Title
  
  Phytomedicine Plus
  
  Volume: 2 Issue: 4 Pages: 100367-100367
- DOI
  10.1016/j.phyplu.2022.100367
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-21K19727, KAKENHI-PROJECT-20H04110, KAKENHI-PROJECT-20K11512
[Journal Article] Asymmetric dimethylarginine accumulation under hyperglycemia facilitates β-cell apoptosis via inhibiting nitric oxide production2022
- Author(s)
  Kaneko Yukiko K.、Morioka Ami、Sano Misaki、Tashiro Maho、Watanabe Naoya、Kasahara Nahoko、Nojiri Masato、Ishiwatari Chihiro、Ichinose Kentaro、Minami Akira、Suzuki Takashi、Yamaguchi Momoka、Kimura Toshihide、Ishikawa Tomohisa
- Journal Title
  
  Biochemical and Biophysical Research Communications
  
  Volume: 637 Pages: 108-116
- DOI
  10.1016/j.bbrc.2022.11.011
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-21K19727, KAKENHI-PROJECT-20H04110, KAKENHI-PROJECT-20K08891, KAKENHI-PROJECT-20K11512
[Journal Article] Na+-dependent inactivation of vascular Na+/Ca2+ exchanger responsible for reduced peripheral blood flow in neuropathic pain model2021
- Author(s)
  Ishida Hirotake、Yamaguchi Momoka、Saito Shin-ya、Furukawa Takuma、Shannonhouse John L.、Kim Yu Shin、Ishikawa Tomohisa
- Journal Title
  
  European Journal of Pharmacology
  
  Volume: 910 Pages: 174448-174448
- DOI
  10.1016/j.ejphar.2021.174448
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-20H04110
[Journal Article] Diacylglycerol kinase δ functions as a proliferation suppressor in pancreatic β‐cells2021
- Author(s)
  Sato Taiji、Ishiwatari Chihiro、Kaneko Yukiko K.、Ishikawa Yoko、Kimura Yuki、Watanabe Naoya、Aoshima Ikumi、Matsuda Yukari、Nakayama Takahiro、Chiba Rina、Fujinuki Takahiro、Iwata Kai、Lu Qiang、Usuki Takako、Sakane Fumio、Ishikawa Tomohisa
- Journal Title
  
  The FASEB Journal
  
  Volume: 35 Issue: 5
- DOI
  10.1096/fj.202001279rr
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-20K11512, KAKENHI-PROJECT-20H03205, KAKENHI-PROJECT-20H04110
[Journal Article] Quantitative real-time measurement of endothelin-1-induced contraction in single non-activated hepatic stellate cells2021
- Author(s)
  Dohi Naoki、Yamaguchi Momoka、Hase Reina、Suzuki Ryosuke、Wakabayashi Yumeto、Nishiyama Ryota、Saito Shin-ya、Ishikawa Tomohisa
- Journal Title
  
  PLOS ONE
  
  Volume: 16 Issue: 8 Pages: e0255656-e0255656
- DOI
  10.1371/journal.pone.0255656
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-19K20186, KAKENHI-PROJECT-20H04110
[Journal Article] Caffeine-induced inversion of prostaglandin E2 effects on hepatic stellate cell activation2021
- Author(s)
  Yamaguchi Momoka、Dohi Naoki、Ooka Akira、Saito Shin-ya、Ishikawa Tomohisa
- Journal Title
  
  Biomedicine & Pharmacotherapy
  
  Volume: 142 Pages: 111989-111989
- DOI
  10.1016/j.biopha.2021.111989
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-19K20186, KAKENHI-PROJECT-20H04110, KAKENHI-PROJECT-21J15529
[Journal Article] Citrus flavonoids as a target for the prevention of pancreatic β-cells dysfunction in diabetes.2020
- Author(s)
  K. Kaneko Yukiko、Kan Toshiyuki、Ishikawa Tomohisa
- Journal Title
  
  Folia Pharmacologica Japonica
  
  Volume: 155 Issue: 4 Pages: 209-213
- DOI
  10.1254/fpj.20024
- NAID
  130007867539
- ISSN
  0015-5691, 1347-8397
- Language
  Japanese
- Data Source
  KAKENHI-PROJECT-20K11512
[Journal Article] The sialidase inhibitor 2,3-dehydro-2-deoxy-N-acetylneuraminic acid is a glucose-dependent potentiator of insulin secretion2020
- Author(s)
  Minami Akira、Fujita Yuka、Shimba Sumika、Shiratori Mako、Kaneko Yukiko K.、Sawatani Toshiaki、Otsubo Tadamune、Ikeda Kiyoshi、Kanazawa Hiroaki、Mikami Yasuyo、Sekita Risa、Kurebayashi Yuuki、Takahashi Tadanobu、Miyagi Taeko、Ishikawa Tomohisa、Suzuki Takashi
- Journal Title
  
  Scientific Reports
  
  Volume: 10 Issue: 1 Pages: 5198-5198
- DOI
  10.1038/s41598-020-62203-8
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-19K07066, KAKENHI-PROJECT-20K21721, KAKENHI-PROJECT-20H04110, KAKENHI-PROJECT-18K19755
[Journal Article] Renoprotective Effects of a Novel Receptor-Interacting Protein Kinase 2 Inhibitor, AS3334034, in Uninephrectomized Adriamycin-Induced Chronic Kidney Disease Rats2020
- Author(s)
  Wada Yusuke、Kondo Mitsuhiro、Sakairi Kumi、Nagashima Akira、Tokita Kenichi、Tominaga Hiroaki、Tomiyama Hiroshi、Ishikawa Tomohisa
- Journal Title
  
  Journal of Pharmacology and Experimental Therapeutics
  
  Volume: 374 Issue: 3 Pages: 428-437
- DOI
  10.1124/jpet.120.265678
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-20H04110, KAKENHI-PROJECT-18K19755
[Journal Article] Differentiation-inducing factor-1 prevents hepatic stellate cell activation through inhibiting GSK3β inactivation2019
- Author(s)
  Furukawa Shohei、Yamaguchi Momoka、Ooka Akira、Kikuchi Haruhisa、Ishikawa Tomohisa、Saito Shin-ya
- Journal Title
  
  Biochemical and Biophysical Research Communications
  
  Volume: 520 Issue: 1 Pages: 140-144
- DOI
  10.1016/j.bbrc.2019.09.117
- Peer Reviewed / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-18K19755, KAKENHI-PROJECT-19K20186, KAKENHI-PROJECT-17H02175
[Journal Article] TRPV2 channels mediate insulin secretion induced by cell swelling in mouse pancreatic β-cells2019
- Author(s)
  Toshiaki Sawatani, Yukiko K. Kaneko, Isao Doutsu, Ai Ogawa, Tomohisa Ishikawa
- Journal Title
  
  Am J Physiol Cell Physiol
  
  Volume: 316 Issue: 3 Pages: C434-C443
- DOI
  10.1152/ajpcell.00210.2017
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-17K01857, KAKENHI-PROJECT-18K19755, KAKENHI-PROJECT-17H02175
[Journal Article] Dual effect of reduced type I diacylglycerol kinase activity on insulin secretion from MIN6 β-cells2019
- Author(s)
  Sawatani Toshiaki、Kaneko Yukiko K.、Ishikawa Tomohisa
- Journal Title
  
  Journal of Pharmacological Sciences
  
  Volume: 140 Issue: 2 Pages: 178-186
- DOI
  10.1016/j.jphs.2019.06.001
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-18K19755, KAKENHI-PROJECT-17H02175, KAKENHI-PROJECT-17K01857
[Journal Article] Alleviation of mechanical stress-induced allodynia by improving blood flow in chronic constriction injury mice2019
- Author(s)
  Ishida Hirotake、Saito Shin-ya、Horie Ayaka、Ishikawa Tomohisa
- Journal Title
  
  European Journal of Pharmacology
  
  Volume: 849 Pages: 67-74
- DOI
  10.1016/j.ejphar.2019.02.002
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-18K19755, KAKENHI-PROJECT-17H02175
[Journal Article] GDP-Bound Rab27a Dissociates from the Endocytic Machinery in a Phosphorylation-Dependent Manner after Insulin Secretion2019
- Author(s)
  Kimura Toshihide、Yamaoka Mami、Terabayashi Takeshi、Kaibuchi Kozo、Ishikawa Tomohisa、Ishizaki Toshimasa
- Journal Title
  
  Biological and Pharmaceutical Bulletin
  
  Volume: 42 Issue: 9 Pages: 1532-1537
- DOI
  10.1248/bpb.b19-00242
- NAID
  130007700076
- ISSN
  0918-6158, 1347-5215
- Year and Date
  2019-09-01
- Language
  English
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-19K08776, KAKENHI-PROJECT-18K19755, KAKENHI-PROJECT-17H02175, KAKENHI-PROJECT-17K08339, KAKENHI-PROJECT-17K09838, KAKENHI-PROJECT-18K16239
[Journal Article] IRR is involved in glucose-induced endocytosis after insulin secretion2019
- Author(s)
  Yamaoka Mami、Terabayashi Takeshi、Nishioka Tomoki、Kaibuchi Kozo、Ishikawa Tomohisa、Ishizaki Toshimasa、Kimura Toshihide
- Journal Title
  
  Journal of Pharmacological Sciences
  
  Volume: 140 Issue: 3 Pages: 300-304
- DOI
  10.1016/j.jphs.2019.07.002
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-19K08776, KAKENHI-PROJECT-18K19755, KAKENHI-PROJECT-17H02175, KAKENHI-PROJECT-17K08339, KAKENHI-PROJECT-17K09838, KAKENHI-PROJECT-18K16239
[Journal Article] Mechanism of Membrane Depolarization Involved in α1A-Adrenoceptor-Mediated Contraction in Rat Tail and Iliac Arteries2019
- Author(s)
 Ishida Hirotake、Saito Shin-ya、Dohi Naoki、Ishikawa Tomohisa
- Journal Title
 
 Biological and Pharmaceutical Bulletin
 
 Volume: 42 Issue: 10 Pages: 1741-1745
- DOI
 10.1248/bpb.b19-00473
- NAID
 130007722436
- ISSN
 0918-6158, 1347-5215
- Year and Date
 2019-10-01
- Language
 English
- Peer Reviewed
- Data Source
 KAKENHI-PROJECT-18K19755, KAKENHI-PROJECT-17H02175
[Journal Article] Differential contribution of calcium channels to α 1 -adrenoceptor-mediated contraction is responsible for diverse responses to cooling between rat tail and iliac arteries2018
- Author(s)
  Ishida Hirotake、Saito Shin-ya、Hishinuma Eita、Kitayama Tomoaki、Ishikawa Tomohisa
- Journal Title
  
  European Journal of Pharmacology
  
  Volume: 826 Pages: 9-16
- DOI
  10.1016/j.ejphar.2018.02.023
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-15K12705, KAKENHI-PROJECT-18K19755, KAKENHI-PROJECT-17H02175
[Journal Article] α1A-Adrenoceptors, but not α1B- or α1D-adrenoceptors, contribute to enhanced contractile response to phenylephrine in cooling conditions in the rat tail artery2018
- Author(s)
  Ishida Hirotake、Saito Shin-ya、Ishikawa Tomohisa
- Journal Title
  
  European Journal of Pharmacology
  
  Volume: 838 Pages: 120-128
- DOI
  10.1016/j.ejphar.2018.09.004
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-18K19755, KAKENHI-PROJECT-17H02175
[Journal Article] Concise synthesis of polymethoxyflavone sudachitin and its derivatives, and biological evaluations2018
- Author(s)
  Sagara Hiroto、Kanakogi Masaki、Tara Yuki、Ouchi Hitoshi、Kimura Junko、Kaneko Yukiko、Inai Makoto、Asakawa Tomohiro、Ishikawa Tomohisa、Kan Toshiyuki
- Journal Title
  
  Tetrahedron Letters
  
  Volume: 59 Issue: 19 Pages: 1816-1818
- DOI
  10.1016/j.tetlet.2018.03.064
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-17K01857, KAKENHI-PROJECT-15K12705, KAKENHI-PROJECT-18K19755, KAKENHI-PUBLICLY-18H04424, KAKENHI-PROJECT-17H02175, KAKENHI-PROJECT-17H03973, KAKENHI-PROJECT-17K15424
[Journal Article] Differential Contribution of Nerve-Derived Noradrenaline to High K+-Induced Contraction Depending on Type of Artery2017
- Author(s)
 Ishida H, Saito S, Hishinuma E, Ishikawa T.
- Journal Title
 
 Biological and Pharmaceutical Bulletin
 
 Volume: 40 Issue: 1 Pages: 56-60
- DOI
 10.1248/bpb.b16-00590
- NAID
 130005188890
- ISSN
 0918-6158, 1347-5215
- Language
 English
- Peer Reviewed / Open Access
- Data Source
 KAKENHI-PROJECT-15K12705, KAKENHI-PROJECT-17H02175
[Journal Article] Caffeine Suppresses the Activation of Hepatic Stellate Cells cAMP-Independently by Antagonizing Adenosine Receptors2017
- Author(s)
  Yamaguchi M, Saito SY, Nishiyama R, Nakamura M, Todoroki K, Toyo'oka T, Ishikawa T.
- Journal Title
  
  Biological and Pharmaceutical Bulletin
  
  Volume: 40 Issue: 5 Pages: 658-664
- DOI
  10.1248/bpb.b16-00947
- NAID
  130005631974
- ISSN
  0918-6158, 1347-5215
- Language
  English
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-15K12705, KAKENHI-PROJECT-16K08200, KAKENHI-PROJECT-17H02175
[Journal Article] Insulinotropic and anti-apoptotic effects of nobiletin in INS-1D β-cells.2017
- Author(s)
  Miki Takii, Yukiko K. Kaneko, Kiriko Akiyama, Yuki Aoyagi, Yuki Tara, Tomohiro Asakawa, Makoto Inai, Toshiyuki Kan, Kiyomitsu Nemoto, Tomohisa Ishikawa
- Journal Title
  
  Journal of Functional Foods
  
  Volume: 30 Pages: 8-15
- DOI
  10.1016/j.jff.2016.12.037
- Peer Reviewed / Acknowledgement Compliant / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-26750336, KAKENHI-PROJECT-15K12705, KAKENHI-PROJECT-17K15424, KAKENHI-PUBLICLY-16H01160, KAKENHI-PROJECT-17H02175, KAKENHI-PROJECT-17H03973
[Journal Article] G-protein coupled estrogen receptor-mediated non-genomic facilitatory effect of estrogen on cooling-induced reduction of skin blood flow in mice.2017
- Author(s)
  Serizawa I, Iwasaki N, Ishida H, Saito S, Ishikawa T.
- Journal Title
  
  Eur J Pharmacol
  
  Volume: 797 Pages: 26-31
- DOI
  10.1016/j.ejphar.2017.01.013
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-15K12705, KAKENHI-PROJECT-17H02175
[Journal Article] Depression of type I diacylglycerol kinases in pancreaticβ-cells from male mice results in impaired insulin secretion2013
- Author(s)
  Kaneko YK, Kobayashi Y, Motoki K, Nakata K, Miyagawa S, Yamamoto M, Hayashi D, Shirai Y, Sakane F, Ishikawa T
- Journal Title
  
  Endocrinology
  
  Volume: 154 Pages: 4089-4098
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-23590192
[Journal Article] Dual Role of Nitric Oxide in Pancreatic β-Cells2013
- Author(s)
 Kaneko KY, Ishikawa T
- Journal Title
 
 J Pharmacol Sci
 
 Volume: 123 Issue: 4 Pages: 295-300
- DOI
 10.1254/jphs.13R10CP
- NAID
 130003382623
- ISSN
 1347-8613, 1347-8648
- Language
 English
- Peer Reviewed
- Data Source
 KAKENHI-PROJECT-23590192
[Journal Article] Involvement of the Autonomic Nervous System in Diurnal Variation of Corrected QT Intervals in Common Marmosets2013
- Author(s)
  Honda M, Komatsu R, Isobe T, Tabo M, Ishikawa T
- Journal Title
  
  J Pharmacol Sci
  
  Volume: 121 Issue: 2 Pages: 131-137
- DOI
  10.1254/jphs.12230FP
- NAID
  10031156942
- ISSN
  1347-8613, 1347-8648
- Language
  English
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-23590192
[Journal Article] Dual role of nitric oxide in pancreaticβ-cells2013
- Author(s)
  Kaneko YK, Ishikawa T
- Journal Title
  
  J Pharmacol Sci
  
  Volume: 123 Pages: 295-300
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-23590192
[Journal Article] Involvement of nitric oxide production in the impairment of skin blood flow response to local cooling in diabetic db/db mice2013
- Author(s)
  Sahara Y, Saito S, Ishikawa T
- Journal Title
  
  Eur J Pharmacol
  
  Volume: 720 Issue: 1-3 Pages: 174-179
- DOI
  10.1016/j.ejphar.2013.10.030
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-23590192
[Journal Article] Depression of type I diacylglycerol kinases in pancreatic β-cells from male mice results in impaired insulin secretion2013
- Author(s)
  Kaneko KY, Kobayashi Y, Motoki K, Nakata K, Miyagawa S, Yamamoto M, Hayashi D, Shirai Y, Sakane F, Ishikawa T
- Journal Title
  
  Endocrinology
  
  Volume: 154 Issue: 11 Pages: 4089-4098
- DOI
  10.1210/en.2013-1356
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-23590192, KAKENHI-PUBLICLY-25116704
[Journal Article] IP_3 receptor-mediated initial Ca^<2+> mobilization constitutes a triggering signal for H_2O_2-induced apoptosis in INS-1 β-cells.2011
- Author(s)
 Takada M, Noguchi A, Sayama Y, Kaneko Y, Ishikawa T.
- Journal Title
 
 Biol.Pharm.Bull. in press
- Peer Reviewed
- Data Source
 KAKENHI-PROJECT-20590085
[Journal Article] IP_3 receptor-mediated initial Ca^<2+> mobilization constitutes a triggering signal for H_2O_2-induced apoptosis in INS-1β-cells2011
- Author(s)
 Takada M, Noguchi A, Sayama Y, Kaneko Y, Ishikawa T
- Journal Title
 
 Biol Pharm Bull
 
 Volume: 34 Pages: 954-958
- Peer Reviewed
- Data Source
 KAKENHI-PROJECT-23590192
[Journal Article] Dual effect of nitric oxide on ATP-sensitive K+ channels in rat pancreatic β-cells2008
- Author(s)
  Sunouchi T, Suzuki K, Nakayama K, Ishikawa T
- Journal Title
  
  Pfltigers Arch-Eur J Physiol 456
  
  Pages: 573-579
- Description
  「研究成果報告書概要(欧文)」より
- Data Source
  KAKENHI-PROJECT-17590224
[Journal Article] Dual effect of nitric oxide on ATP-sensitive K+ channels in rat pancreatic β-cells2008
- Author(s)
  Takaaki, Sunouchi, Kimiaki, Suzuki, Koichi, Nakayama, Tomohisa, Ishikawa
- Journal Title
  
  Pflugers Archiv-European Journal of Physiology (in press)
- Description
  「研究成果報告書概要(欧文)」より
- Data Source
  KAKENHI-PROJECT-18590064
[Journal Article] cGMP-independent antiapoptotic effect of nitric oxide on thapsigargin-induced apoptosis in the pancreatic β-cell line INS-1.2008
- Author(s)
  Noguchi A, Takada M, Nakayama K, Ishikawa T.
- Journal Title
  
  Life Sci. 83
  
  Pages: 865-870
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-20590085
[Journal Article] ラット、マウスを用いたIn Vivo皮膚微小循環解析法2008
- Author(s)
  石川智久
- Journal Title
  
  日本薬理学雑誌 132
  
  Pages: 79-82
- NAID
  10024383474
- Data Source
  KAKENHI-PROJECT-20590085
[Journal Article] Dual effect of nitric oxide on ATP-sensitive K+ channels in rat pancreatic β-cells2008
- Author(s)
  Takaaki Sunouchi, Kimiaki Suzuki, Koichi Nakayama, Tomohisa Ishikawa
- Journal Title
  
  Pflugers Archiv-European Journal of Physiology (in press)
- Description
  「研究成果報告書概要(和文)」より
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-18590064
[Journal Article] Dual effect of nitric oxide on ATP-sensitive K^+ channels in rat pancreatic β-cells2008
- Author(s)
  Takaaki Sunouchi, Kimiaki Suzuki, Koichi Nakavama, Tomohisa Ishikawa
- Journal Title
  
  Pflugers Archiv-European Journal of Physiology in press
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-18590064
[Journal Article] Role of α_<2c> -adrenoceptors in local cooling-induced reduction of skin blood flow in mice2007
- Author(s)
 Masaki Honda, Mika Suzuki, Kochi Nakayama, Tomohisa Ishikawa
- Journal Title
 
 Br J. Pharmacol. 152
 
 Pages: 91-100
- Peer Reviewed
- Data Source
 KAKENHI-PROJECT-18590064
[Journal Article] Role of α_2C-adrenoceptors in local cooling-induced reduction of skin blood flow in mice2007
- Author(s)
  Masaki Honda, Mika Suzuki, Koichi Nakavama, Tomohisa Ishikawa
- Journal Title
  
  Br.J.Pharmacol 152
  
  Pages: 91-100
- Description
  「研究成果報告書概要(和文)」より
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-18590064
[Journal Article] Role of a_<2c>-adrenoceptors in local cooling-induced reduction of skin blood flow in mice2007
- Author(s)
 Masaki, Honda, Mika, Suzuki, Koichi, Nakayama, Tomohisa, Ishikawa
- Journal Title
 
 Br J. Pharmacol 152
 
 Pages: 91-100
- Description
 「研究成果報告書概要(欧文)」より
- Data Source
 KAKENHI-PROJECT-18590064
[Journal Article] Role of α_(2c)-adrenoceptors in local cooling-induced reduction of skin blood flow in mice2007
- Author(s)
  Honda, M, Suzuki, M, Nakayama, K, Ishikawa, T
- Journal Title
  
  Br J Pharmacol 152
  
  Pages: 91-100
- Description
  「研究成果報告書概要(欧文)」より
- Data Source
  KAKENHI-PROJECT-17590224
[Journal Article] Involvement of stretch-activated cation channels in hypotonically induced insulin secretion in rat pancreatic β-cells2006
- Author(s)
  Miki Takii, Tomohisa Ishikawa, Hidetaka Tsuda, Kazumitsu Kanatani, Takashi, Sunouchi, Yukiko Kaneko, Koichi Nakayama
- Journal Title
  
  Am.J.Physiol.Cell Physiol 291
- Description
  「研究成果報告書概要(和文)」より
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-18590064
[Journal Article] Passive stretching produces Akt- and MAPK-dependent augmentations of GLUT4 translocation and glucose uptake in skeletal muscles of mice2006
- Author(s)
  Yoshihiko, Ito, Kazuo, Obara, Rikuko, Ikeda, Megumi, Ishii, Yoshiyuki, Tanabe, Tomohisa, Ishikawa, Koichi, Nakayama
- Journal Title
  
  Pflugers Archiv-European Journal of Physiology 451
  
  Pages: 803-813
- Description
  「研究成果報告書概要(欧文)」より
- Data Source
  KAKENHI-PROJECT-18590064
[Journal Article] Arp感受性K^+チャネルを介さないグルコース応答性インスリン分泌機構NOおよび細胞膨張によるインスリン分泌調節を中心に2006
- Author(s)
  石川智久
- Journal Title
  
  日本薬理学雑誌 128
  
  Pages: 208-213
- Description
  「研究成果報告書概要(和文)」より
- Data Source
  KAKENHI-PROJECT-17590224
[Journal Article] ATP感受性K^+チャネルを介さないグルコース応答性インスリン分泌機構〜NOおよび細胞膨張によるインスリン分泌調節を中心に〜2006
- Author(s)
  石川智久、中山貢一
- Journal Title
  
  日本薬理学雑誌 128
  
  Pages: 208-213
- NAID
  10018811334
- Description
  「研究成果報告書概要(和文)」より
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-18590064
[Journal Article] Involvement of stretch-activated cation channels in hypotonically induced insulin secretion in rat pancreatic β-cells2006
- Author(s)
  Takii, M, Ishikawa, T, Tsuda, H, Kanatani, K, Sunouchi, T, Kaneko, Y, Nakayama, K
- Journal Title
  
  Am J Physiol Cell Physiol 291
- Description
  「研究成果報告書概要(欧文)」より
- Data Source
  KAKENHI-PROJECT-17590224
[Journal Article] Involvement of stretch-activated cation channels in hypotonically induced insulin secretion in rat pancreatic 13-cells2006
- Author(s)
  Miki, Takii, Tomohisa, Ishikawa, Hidetaka, Tsuda, Kazumitsu, Kanatani, Takashi, Sunouchi, Yukiko, Kaneko, Koichi, Nakayama
- Journal Title
  
  Am. J. Physiol. Cell Physiol 291
- Description
  「研究成果報告書概要(欧文)」より
- Data Source
  KAKENHI-PROJECT-18590064
[Journal Article] Local regulation of skin blood flow during cooling involving presynaptic P2 purinoceptors in rats2006
- Author(s)
  Koganezawa, T, Ishikawa, T, Fujita, Y, Yamashita, T, Tajima, T, Honda, M, Nakayama, K
- Journal Title
  
  Br J Pharmacol 148
  
  Pages: 579-586
- Description
  「研究成果報告書概要(欧文)」より
- Data Source
  KAKENHI-PROJECT-17590224
[Journal Article] Local regulation of skin blood flow during cooling involving presynaptic P2 purinoceptors in rats2006
- Author(s)
  Tadachika Koganezawa, Tomohisa Ishikawa, Yukiyoshi Fujita, Tomonari Yamashita, Takako Tajima, Masaki Honda, Koichi Nakayama
- Journal Title
  
  Br.J.Pharmacol 148
  
  Pages: 579-586
- Description
  「研究成果報告書概要(和文)」より
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-18590064
[Journal Article] Local regulation of skin blood flow during cooling involving presynaptic P2 purinoceptors in rats2006
- Author(s)
  Tadachika, Koganezawa, Tomohisa, Ishikawa, Yukiyoshi, Fujita, Tomonari, Yamashita, Takako, Tajima, Masaki, Honda, Koichi, Nakayama
- Journal Title
  
  Br. J. Pharmacol 148
  
  Pages: 579-586
- Description
  「研究成果報告書概要(欧文)」より
- Data Source
  KAKENHI-PROJECT-18590064
[Journal Article] Glucose-induced insulin secretion independent of ATP-sensitive K+ channels2006
- Author(s)
  Tomohisa, Ishikawa, Koichi, Nakayama
- Journal Title
  
  Folia Pharmacol. Jpn 128
  
  Pages: 208-213
- NAID
  10018811334
- Description
  「研究成果報告書概要(欧文)」より
- Data Source
  KAKENHI-PROJECT-18590064
[Journal Article] Passive stretching produces Akt- and MAPK-dependent augmentations of GLUT4 translocation and glucose uptake in skeletal muscles of mice2006
- Author(s)
  Ito, Y, Obara, K, Ikeda, R, Ishii, M, Tanabe, Y, Ishikawa, T, Nakayama, K
- Journal Title
  
  Pfltigers Arch-Eur J Physiol 451
  
  Pages: 803-813
- Description
  「研究成果報告書概要(欧文)」より
- Data Source
  KAKENHI-PROJECT-17590224
[Journal Article] Passive stretching produces Akt- and MAPK-dependent augmentations of GLUT4 translocation and glucose uptake in skeletal muscles of mice2006
- Author(s)
  Yoshihiko Ito, Kazuo Obara, Rikuko Ikeda, Megumi Ishii, Yoshiyuki Tanabe, Tomohisa Ishikawa, Koichi Nakayama
- Journal Title
  
  Pflugers Archiv-European Journal of Physiology 451
  
  Pages: 803-813
- Description
  「研究成果報告書概要(和文)」より
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-18590064
[Journal Article] ATP感受性K^+チャンネルを介さないグルコース応答性インスリン分泌機構 NOおよび細胞膨張によるインスリン分泌調整を中心に2006
- Author(s)
  石川智久
- Journal Title
  
  日本薬理学雑誌 128
  
  Pages: 208-213
- Data Source
  KAKENHI-PROJECT-17590224
[Journal Article] ATP感受性K^+チャネルを介さないグルコース応答性インスリン分泌機構〜NOならびに細胞膨張によるインスリン分泌調節を中心に〜2006
- Author(s)
  石川智久
- Journal Title
  
  日本薬理学雑誌 128
  
  Pages: 208-213
- Data Source
  KAKENHI-PROJECT-18590064
[Journal Article] Interactive role of protein kinase CS with Rho-kinase in the development of cerebral vasospasm in a canine two-hemorrhage model2005
- Author(s)
  Obara, K, Nishizawa, S, Koide, M, Nozawa, K, Mitate, A, Ishikawa, T, Nakayama, K
- Journal Title
  
  J Vasc Res 42
  
  Pages: 67-76
- Description
  「研究成果報告書概要(欧文)」より
- Data Source
  KAKENHI-PROJECT-17590224
[Journal Article] Facilitation of L-type Ca^(2+) currents by fluid flow in rabbit cerebral artery myocytes2005
- Author(s)
  Amano, S, Ishikawa, T, Nakayama, K
- Journal Title
  
  J Pharmacol Sci 98
  
  Pages: 425-429
- NAID
  10025729710
- Description
  「研究成果報告書概要(欧文)」より
- Data Source
  KAKENHI-PROJECT-17590224
[Journal Article] Ionic mechanism for contractile response to hyposmotic challenge in canine basilar arteries2005
- Author(s)
  Shunsuke, Yano, Tomohisa, Ishikawa, Hidetaka, Tsuda, Kazuo, Obara, Koichi, Nakayama
- Journal Title
  
  Am. J. Physiol. Cell Physiol 288
- Description
  「研究成果報告書概要(欧文)」より
- Data Source
  KAKENHI-PROJECT-18590064
[Journal Article] Involvement of novel protein kinase C isoforms in carbachol-stimulated insulin secretion from rat pancreatic islets2005
- Author(s)
  Tomohisa Ishikawa
- Journal Title
  
  Life Sci 77
  
  Pages: 462-469
- Description
  「研究成果報告書概要(和文)」より
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-17590224
[Journal Article] Involvement of novel protein kinase C isoforms in carbachol-stimulated insulin secretion from rat pancreatic islets2005
- Author(s)
  Ishikawa, T, Iwasaki, E, Kanatani, K, Sugino, F, Kaneko, Y, Obara, K, Nakayama, K
- Journal Title
  
  Life Sci 77
  
  Pages: 462-469
- Description
  「研究成果報告書概要(欧文)」より
- Data Source
  KAKENHI-PROJECT-17590224
[Journal Article] Ionic mechanism of myogenic response in cerebral arteries2005
- Author(s)
  Tomohisa, Ishikawa, Koichi, Nakayama
- Journal Title
  
  Folia Pharmacol. Jpn 126
  
  Pages: 262-266
- NAID
  10016912579
- Description
  「研究成果報告書概要(欧文)」より
- Data Source
  KAKENHI-PROJECT-18590064
[Journal Article] 脳血管におけるストレッチと低浸透圧刺激に対する筋原性反応のイオンメカニズム2005
- Author(s)
  石川智久
- Journal Title
  
  日本薬理学雑誌 126
  
  Pages: 262-266
- NAID
  10016912579
- Description
  「研究成果報告書概要(和文)」より
- Data Source
  KAKENHI-PROJECT-17590224
[Journal Article] Involvement of novel protein kinase C isoforms in carbachol-stimulated insulin secretion from rat pancreatic islets.2005
- Author(s)
  Tomohisa Ishikawa
- Journal Title
  
  Life Sci 77
  
  Pages: 462-469
- Data Source
  KAKENHI-PROJECT-17590224
[Journal Article] Facilitation of L-type Ca^<2+> currents by fluid flow in rabbit cerebral artery myocytes2005
- Author(s)
 Satoshi, Amano, Tomohisa, Ishikawa, Koichi, Nakayama
- Journal Title
 
 J. Pharmacol. Sci 98
 
 Pages: 425-429
- NAID
 10025729710
- Description
 「研究成果報告書概要(欧文)」より
- Data Source
 KAKENHI-PROJECT-18590064
[Journal Article] Ionic mechanism for contractile response to hyposmotic challenge in canine basilar arteries2005
- Author(s)
  Yano, S, Ishikawa, T, Tsuda, H, Obara, K, Nakayama, K
- Journal Title
  
  Am J Physiol Cell Physiol 288
- Description
  「研究成果報告書概要(欧文)」より
- Data Source
  KAKENHI-PROJECT-17590224
[Presentation] 膵β細胞の核内におけるジアシルグリセロールキナーゼζの機能解析2023
- Author(s)
  渡邉直也、金子雪子、石原寿光、石川智久
- Organizer
  第66回日本糖尿病学会年次学術集会
- Data Source
  KAKENHI-PROJECT-23K10803
[Presentation] 肝星細胞の活性化に対する植物由来エキソソーム様ナノ粒子の作用機序2023
- Author(s)
  岡部磨幸、山口桃生、大岡央、森野純鈴、柴田涼吾、金沢貴憲、金子雪子、石川智久
- Organizer
  日本薬学会第143年会
- Data Source
  KAKENHI-PROJECT-20H04110
[Presentation] Exploration of signaling molecules involved in the reversion of activated hepatic stellate cells utilizing structural modification of small molecule compounds2023
- Author(s)
  Akira Ooka, Momoka Yamaguchi, Yuzuki Nagasawa, Kenji Yamashita, Kaori Inamura, Makoto Inai, Shin-ya Saito, Yoshitaka Hamashima, Tomohisa Ishikawa
- Organizer
  第97回日本薬理学会年会・第44回日本臨床薬理学会学術総会
- Data Source
  KAKENHI-PROJECT-21K19727
[Presentation] 肝星細胞の分化転換調節薬の構造に基づいた肝線維化治療標的の探索2023
- Author(s)
  大岡央、山口桃生、長澤柚希、本橋南奈実、山下賢二、濱島義隆、齊藤真也、石川智久
- Organizer
  日本薬学会第143年会
- Data Source
  KAKENHI-PROJECT-20H04110
[Presentation] Prostaglandin E2とCaffeineの併用はNRF2の転写亢進を介して肝星細胞の活性化を抑制する2023
- Author(s)
  渡辺雄太，土肥直貴，山口桃生，大岡央,齊藤真也，石川智久
- Organizer
  次世代を担う若手のための創薬・医療薬理シンポジウム
- Data Source
  KAKENHI-PROJECT-21K19727
[Presentation] Prostaglandin E2とCaffeine共処置によるp62のリン酸化および凝集体形成の促進はNRF2の転写亢進を誘導して肝星細胞の活性化を抑制する2023
- Author(s)
  渡辺雄太、山口桃生、土肥直貴、大岡央、齊藤真也、石川智久
- Organizer
  日本病院薬剤師会東海ブロック・日本薬学会東海支部合同学術大会2023
- Data Source
  KAKENHI-PROJECT-23K28004
[Presentation] 肝星細胞の分化転換調節薬の構造に基づいた肝線維化治療標的の探索2023
- Author(s)
  大岡央、山口桃生、長澤柚希、本橋南奈実、山下賢二、濱島義隆、齊藤真也、石川智久
- Organizer
  日本薬学会第143年会
- Data Source
  KAKENHI-PROJECT-21K19727
[Presentation] 抗肝線維化作用を有する低分子化合物の標的分子の探索2023
- Author(s)
  大岡央、山口桃生、長澤柚希、山下賢二、本橋南奈実、齊藤真也、濱島義隆、石川智久
- Organizer
  第147回日本薬理学会関東部会
- Data Source
  KAKENHI-PROJECT-20H04110
[Presentation] 膵β細胞アポトーシスに対する植物由来エキソソーム様ナノ粒子の効果の検討2023
- Author(s)
  柴田涼吾、金子雪子、山口桃生、森野純鈴、金沢貴憲、石川智久
- Organizer
  次世代を担う創薬医療薬理シンポジウム2023
- Data Source
  KAKENHI-PROJECT-23K10803
[Presentation] 肝星細胞の活性化に対する植物由来エキソソーム様ナノ粒子の作用機序2023
- Author(s)
  岡部磨幸、山口桃生、大岡央、森野純鈴、柴田涼吾、金沢貴憲、金子雪子、石川智久
- Organizer
  日本薬学会第143年会
- Data Source
  KAKENHI-PROJECT-21K19727
[Presentation] 構造活性相関をベースとした肝線維化治療標的分子の探索2023
- Author(s)
  山口桃生、大岡央、石川智久
- Organizer
  日本薬学会第143年会
- Invited
- Data Source
  KAKENHI-PROJECT-20H04110
[Presentation] Insulin secretory and anti-apoptotic effect of apigenin on INS-ID pancreatic β-cell.2023
- Author(s)
  Stella Amarachi Ihim, Yukiko K. Kaneko, Moe Yamamoto, Tomohisa Ishikawa
- Organizer
  第97回日本薬理学会年会・第44回日本臨床薬理学会学術総会
- Data Source
  KAKENHI-PROJECT-23K10803
[Presentation] Involvement of NRF2 transcription activity in prostaglandin E2-induced facilitation of the inhibitory effect of caffeine on hepatic stellate cell activation2023
- Author(s)
  Watanabe Yuta，Momoka Yamaguchi，Naoki Dohi，Akira Ooka，Shin-ya Saito，Tomohisa Ishikawa
- Organizer
  第97回日本薬理学会年会・第44回日本臨床薬理学会学術総会
- Data Source
  KAKENHI-PROJECT-23K28004
[Presentation] Prostaglandin E2とCaffeineの併用はNRF2の転写亢進を介して肝星細胞の活性化を抑制する2023
- Author(s)
  渡辺雄太，土肥直貴，山口桃生，大岡央,齊藤真也，石川智久
- Organizer
  次世代を担う若手のための創薬・医療薬理シンポジウム
- Data Source
  KAKENHI-PROJECT-23K28004
[Presentation] シークワーサー果皮抽出物の経口摂取はマウス膵β細胞量保持による抗糖尿病効果を示す2023
- Author(s)
  梶萌、金子雪子、Ihim Stella、狩野蘭、石川智久
- Organizer
  第148回日本薬理学会関東部会
- Data Source
  KAKENHI-PROJECT-23K10803
[Presentation] 構造活性相関をベースとした肝線維化治療標的分子の探索2023
- Author(s)
  山口桃生、大岡央、石川智久
- Organizer
  日本薬学会第143年会
- Invited
- Data Source
  KAKENHI-PROJECT-21K19727
[Presentation] 細胞性粘菌由来低分子化合物DIF-1 による抗肝線維化作用の解析2023
- Author(s)
  大岡央、山口桃生、山下賢二、齊藤真也、濱島義隆、石川智
- Organizer
  次世代を担う若手のための創薬・医療薬理シンポジウム
- Data Source
  KAKENHI-PROJECT-21K19727
[Presentation] Prostaglandin E2とCaffeineの併用はNRF2の転写亢進を介して肝星細胞の活性化を抑制する2023
- Author(s)
  渡辺雄太，土肥直貴，山口桃生，大岡央,齊藤真也，石川智久
- Organizer
  生体機能と創薬シンポジウム 2023
- Data Source
  KAKENHI-PROJECT-21K19727
[Presentation] Treatment of hepatocytes with palmitic acid induces the release of extracellular vesicles with tropism to activated hepatic stellate cells2023
- Author(s)
  Yuta Watanabe，Momoka Yamaguchi，Takanori Kanazawa，Sumire Morino，Shingo Iioka，Naoki Dohi，Kenjirou Higashi，Hiromu Kondo，Tomohisa Ishikawa
- Organizer
  日本薬物動態学会第38回年会・第23回シトクロムP450国際会議国際合同大会
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-23K28004
[Presentation] 抗肝線維化作用を有する低分子化合物の標的分子の探索2023
- Author(s)
  大岡央、山口桃生、長澤柚希、山下賢二、本橋南奈実、齊藤真也、濱島義隆、石川智久
- Organizer
  第147回日本薬理学会関東部会
- Data Source
  KAKENHI-PROJECT-21K19727
[Presentation] Evaluation of the anti-diabetic effect of flavonoids from natural products in INS-1β-cells2023
- Author(s)
  Mikana Sugimori, Yukiko K. Kaneko, Megumi Kaji, Ran Kano, Yoshiki Maeda, Tomohisa Ishikawa
- Organizer
  The Joint Symposium of University of Shizuoka, Khon Kaen University and Chiang Mai University on Pharmacology and Pharmacy
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-23K10803
[Presentation] Inhibition of adenosine receptors induces the inversion of prostaglandin E2 effects on hepatic stellate cell activation2023
- Author(s)
  Momoka Yamaguchi, Naoki Dohi, Yuta Watanabe, Akira Ooka, Shin-ya Saito, Tomohisa Ishikawa
- Organizer
  19th World Congress of Basic and Clinical Pharmacology
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-21K19727
[Presentation] 細胞性粘菌由来低分子化合物DIF-1 による抗肝線維化作用の解析2023
- Author(s)
  大岡央、山口桃生、山下賢二、齊藤真也、濱島義隆、石川智久
- Organizer
  生体機能と創薬シンポジウム 2023
- Data Source
  KAKENHI-PROJECT-21K19727
[Presentation] Prostaglandin E2とCaffeine共処置によるp62のリン酸化および凝集体形成の促進はNRF2の転写亢進を誘導して肝星細胞の活性化を抑制する2023
- Author(s)
  渡辺雄太、山口桃生、土肥直貴、大岡央、齊藤真也、石川智久
- Organizer
  日本病院薬剤師会東海ブロック・日本薬学会東海支部合同学術大会2023
- Data Source
  KAKENHI-PROJECT-21K19727
[Presentation] 植物由来エキソソーム様ナノ粒子が肝星細胞の活性化制御および細胞への取り込みに及ぼす影響2023
- Author(s)
  森野純鈴、山口桃生、岡部磨幸、河合佑美、金子雪子、柴田涼吾、大岡央、金沢貴憲、石川智久
- Organizer
  第44回生体膜と薬物の相互作用シンポジウム
- Data Source
  KAKENHI-PROJECT-21K19727
[Presentation] Involvement of NRF2 transcription activity in prostaglandin E2-induced facilitation of the inhibitory effect of caffeine on hepatic stellate cell activation2023
- Author(s)
  Yuta Watanabe，Momoka Yamaguchi，Naoki Dohi，Akira Ooka，Shin-ya Saito，Tomohisa Ishikawa
- Organizer
  第97回日本薬理学会年会・第44回日本臨床薬理学会学術総会
- Data Source
  KAKENHI-PROJECT-21K19727
[Presentation] Treatment of hepatocytes with palmitic acid induces the release of extracellular vesicles with tropism to activated hepatic stellate cells2023
- Author(s)
  Yuta Watanabe，Momoka Yamaguchi，Takanori Kanazawa，Sumire Morino，Shingo Iioka，Naoki Dohi，Kenjirou Higashi，Hiromu Kondo，Tomohisa Ishikawa
- Organizer
  日本薬物動態学会第38回年会・第23回シトクロムP450国際会議国際合同大会
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-21K19727
[Presentation] Prostaglandin E2とCaffeineの併用はNRF2の転写亢進を介して肝星細胞の活性化を抑制する2023
- Author(s)
  渡辺雄太，土肥直貴，山口桃生，大岡央,齊藤真也，石川智久
- Organizer
  生体機能と創薬シンポジウム 2023
- Data Source
  KAKENHI-PROJECT-23K28004
[Presentation] β細胞に発現するDGKζはインスリン分泌の促進因子である2023
- Author(s)
  渡邉直也、金子雪子、石原寿光、石川智久
- Organizer
  第96回日本生化学会大会
- Data Source
  KAKENHI-PROJECT-23K10803
[Presentation] 植物由来エキソソーム様ナノ粒子が膵β細胞アポトーシスに及ぼす影響の検討2023
- Author(s)
  柴田涼吾、金子雪子、山口桃生、森野純鈴、金沢貴憲、石川智久
- Organizer
  日本病院薬剤師会東海ブロック・日本薬学会東海支部合同学術大会2023
- Data Source
  KAKENHI-PROJECT-23K10803
[Presentation] Insulin-secretory and anti-apoptotic effects of apigenin in INS-ID pancreatic β-cells.2023
- Author(s)
  Stella Amarachi Ihim, Yukiko K. Kaneko, Moe Yamamoto, Tomohisa Ishikawa
- Organizer
  International Diabetes Federation Western Pacific Region Congress 2023
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-23K10803
[Presentation] nhibition of adenosine receptors induces the inversion of prostaglandin E2 effects on hepatic stellate cell activation2023
- Author(s)
  Momoka Yamaguchi, Naoki Dohi, Yuta Watanabe, Akira Ooka, Shin-ya Saito, Tomohisa Ishikawa
- Organizer
  19th World Congress of Basic and Clinical Pharmacology
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-23K28004
[Presentation] Analysis of the mechanism underlying the DIF-1 effect on HSCs transdifferentiation2023
- Author(s)
  Akira Ooka, Momoka Yamaguchi, Nanami Motohashi, Shin-ya Saito, Tomohisa Ishikawa
- Organizer
  19th World Congress of Basic and Clinical Pharmacology
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-21K19727
[Presentation] 膵島に集積する脂質ナノ粒子の開発を目指したリン脂質の組成および粒子径の検討2023
- Author(s)
  佐藤蓮、金子雪子、金沢貴憲、芹澤未来、大岡央、山口桃生、真野結奈、飯岡真吾、尾熊貴之、近藤啓、石川智久
- Organizer
  第44回生体膜と薬物の相互作用シンポジウム
- Data Source
  KAKENHI-PROJECT-23K10803
[Presentation] 肝障害ex vivoモデルを用いた創薬スクリーニング系の構築2022
- Author(s)
  高橋亮汰、山口桃生、森野純鈴、岡部麿幸、大岡央、石川智久
- Organizer
  生体機能と創薬シンポジウム2022
- Data Source
  KAKENHI-PROJECT-20H04110
[Presentation] 肝障害ex vivoモデルを用いた創薬スクリーニング系の構築2022
- Author(s)
  高橋亮汰、山口桃生、森野純鈴、岡部麿幸、大岡央、石川智久
- Organizer
  生体機能と創薬シンポジウム2022
- Data Source
  KAKENHI-PROJECT-21K19727
[Presentation] ジアシルグリセロールキナーゼζの膵β細胞での局在および機能解析2022
- Author(s)
  渡邉直也、金子雪子、石川智久
- Organizer
  日本薬学会第142回年会
- Data Source
  KAKENHI-PROJECT-20H04110
[Presentation] アルギニンメチル基転移酵素PRMT5は肝線維化を促進性に制御する2022
- Author(s)
  山下日菜子、山口桃生、刀坂泰史、大岡央、森本達也、石川智久
- Organizer
  次世代を担う若手のための創薬・医療薬理シンポジウム2022
- Data Source
  KAKENHI-PROJECT-20H04110
[Presentation] PRMT5欠損マウスにおける肝線維化発症抑制機構の解明2022
- Author(s)
  山下日菜子、山口桃生、刀坂泰史、大岡央、森本達也、石川智久
- Organizer
  静岡実験動物研究会令和4年度大会
- Data Source
  KAKENHI-PROJECT-21K19727
[Presentation] 肝線維化ex vivoモデルを用いた抗線維化活性評価系の確立2022
- Author(s)
  高橋亮汰、山口桃生、森野純鈴、岡部磨幸、大岡央、石川智久
- Organizer
  第96回日本薬理学会年会
- Data Source
  KAKENHI-PROJECT-21K19727
[Presentation] Evaluation of the anti-diabetic effect of apigenin on INS-1D pancreatic β -cell2022
- Author(s)
  Ihim Stella、金子雪子、山本萌絵、石川智久
- Organizer
  第146回日本薬理学会関東部会
- Data Source
  KAKENHI-PROJECT-20K11512
[Presentation] 柑橘果皮成分ポリメトキシフラボノイドの膵β細胞機能に対する活性の比較研究2022
- Author(s)
  狩野蘭、金子雪子、多良勇輝、山本萌絵、梶萌、石川智久
- Organizer
  生体機能と創薬シンポジウム2022
- Data Source
  KAKENHI-PROJECT-20K11512
[Presentation] アルギニンメチル基転移酵素PRMT5は肝線維化を促進性に制御する2022
- Author(s)
  山下日菜子、山口桃生、刀坂泰史、大岡央、森本達也、石川智久
- Organizer
  生体機能と創薬シンポジウム2022
- Data Source
  KAKENHI-PROJECT-20H04110
[Presentation] Investigation of the anti-diabetic effect of apigenin on the function of INS-1D pancreatic β-cell2022
- Author(s)
  Stella Amarachi Ihim、Yukiko K. Kaneko、Moe Yamamoto、Yuma Hayakawa、Takuomi Hosaka、Koichi Yoshinari、Tomohisa Ishikawa
- Organizer
  次世代を担う若手のための創薬・医療薬理シンポジウム2022
- Data Source
  KAKENHI-PROJECT-20K11512
[Presentation] 脂肪酸曝露が肝実質細胞由来細胞外小胞の活性型肝星細胞への取り込みに及ぼす影響2022
- Author(s)
  森野純鈴、山口桃生、金沢貴憲、飯岡真吾、東顕二郎、渡辺雄太、土肥直貴、近藤啓、石川智久
- Organizer
  第43回生体膜と薬物の相互作用シンポジウム
- Data Source
  KAKENHI-PROJECT-20H04110
[Presentation] 脂肪酸曝露が肝実質細胞由来細胞外小胞の活性型肝星細胞への取り込みに及ぼす影響2022
- Author(s)
  森野純鈴、山口桃生、金沢貴憲、飯岡真吾、東顕二郎、渡辺雄太、土肥直貴、近藤啓、石川智久
- Organizer
  第43回生体膜と薬物の相互作用シンポジウム
- Data Source
  KAKENHI-PROJECT-21K19727
[Presentation] 肝線維化治療薬開発に向けた肝星細胞形質転換シグナル制御の新展開2022
- Author(s)
  大岡央、山口桃生、齊藤真也、石川智久
- Organizer
  次世代を担う若手のための創薬・医療薬理シンポジウム2022
- Data Source
  KAKENHI-PROJECT-20H04110
[Presentation] 肝線維化治療薬開発に向けた肝星細胞形質転換シグナル制御の新展開2022
- Author(s)
  大岡央、山口桃生、齊藤真也、石川智久
- Organizer
  次世代を担う若手のための創薬・医療薬理シンポジウム2022
- Data Source
  KAKENHI-PROJECT-21K19727
[Presentation] PRMT5欠損マウスにおける肝線維化発症抑制機構の解明2022
- Author(s)
  山下日菜子、山口桃生、刀坂泰史、大岡央、森本達也、石川智久
- Organizer
  静岡実験動物研究会令和4年度大会
- Data Source
  KAKENHI-PROJECT-20H04110
[Presentation] 肝実質細胞由来エクソソームの物性ならびに肝星細胞への取り込みの評価2022
- Author(s)
  森野純鈴、山口桃生、金沢貴憲、飯岡真吾、土肥直貴、近藤啓、石川智久
- Organizer
  日本薬学会第142回年会
- Data Source
  KAKENHI-PROJECT-20H04110
[Presentation] ジアシルグリセロールキナーゼζの膵β細胞での局在および機能解析2022
- Author(s)
  渡邉直也、金子雪子、石川智久
- Organizer
  日本薬学会第142回年会（名古屋）
- Data Source
  KAKENHI-PROJECT-20K11512
[Presentation] 肝障害ex vivoモデルを用いた創薬スクリーニング系の構築2022
- Author(s)
  高橋亮汰、山口桃生、森野純鈴、岡部麿幸、大岡央、石川智久
- Organizer
  次世代を担う若手のための創薬・医療薬理シンポジウム2022
- Data Source
  KAKENHI-PROJECT-21K19727
[Presentation] アルギニンメチル基転移酵素PRMT5は肝線維化を促進性に制御する2022
- Author(s)
  山下日菜子、山口桃生、刀坂泰史、大岡央、森本達也、石川智久
- Organizer
  生体機能と創薬シンポジウム2022
- Data Source
  KAKENHI-PROJECT-21K19727
[Presentation] 肝障害ex vivoモデルを用いた創薬スクリーニング系の構築2022
- Author(s)
  高橋亮汰、山口桃生、森野純鈴、岡部麿幸、大岡央、石川智久
- Organizer
  次世代を担う若手のための創薬・医療薬理シンポジウム2022
- Data Source
  KAKENHI-PROJECT-20H04110
[Presentation] ジアシルグリセロールキナーゼζの膵β細胞内局在と機能の関連解析2022
- Author(s)
  渡邉直也、金子雪子、石川智久
- Organizer
  第96回日本薬理学会年会
- Data Source
  KAKENHI-PROJECT-20K11512
[Presentation] 肝星細胞の形質転換を制御する低分子化合物DIF-1の肝線維化治療薬としての可能性2022
- Author(s)
  大岡央、本橋南奈実、山口桃生、齊藤真也、石川智久
- Organizer
  日本薬学会第142回年会
- Data Source
  KAKENHI-PROJECT-20H04110
[Presentation] 肝星細胞活性化へのPRMT5の関与2022
- Author(s)
  山下日菜子、山口桃生、刀坂泰史、大岡央、森本達也、石川智久
- Organizer
  第96回日本薬理学会年会
- Data Source
  KAKENHI-PROJECT-20H04110
[Presentation] 肝星細胞活性化へのPRMT5の関与2022
- Author(s)
  山下日菜子、山口桃生、刀坂泰史、大岡央、森本達也、石川智久
- Organizer
  第96回日本薬理学会年会
- Data Source
  KAKENHI-PROJECT-21K19727
[Presentation] インスリン分泌および膵β細胞増殖に対するジアシルグリセロールキナーゼζの機能解析2022
- Author(s)
  渡邉直也、金子雪子、石川智久
- Organizer
  第68回日本薬学会東海支部総会・大会
- Data Source
  KAKENHI-PROJECT-20K11512
[Presentation] アルギニンメチル基転移酵素PRMT5は肝線維化を促進性に制御する2022
- Author(s)
  山下日菜子、山口桃生、刀坂泰史、大岡央、森本達也、石川智久
- Organizer
  次世代を担う若手のための創薬・医療薬理シンポジウム2022
- Data Source
  KAKENHI-PROJECT-21K19727
[Presentation] 肝線維化ex vivoモデルを用いた抗線維化活性評価系の確立2022
- Author(s)
  高橋亮汰、山口桃生、森野純鈴、岡部磨幸、大岡央、石川智久
- Organizer
  第96回日本薬理学会年会
- Data Source
  KAKENHI-PROJECT-20H04110
[Presentation] ノビレチンの膵β細胞に対する抗アポトーシス作用機序の解析2022
- Author(s)
  梶萌、金子雪子、石川智久
- Organizer
  第96回日本薬理学会年会
- Data Source
  KAKENHI-PROJECT-20K11512
[Presentation] 膵β細胞におけるジアシルグリセロールキナーゼζの局在と機能解析2022
- Author(s)
  渡邉直也、金子雪子、石川智久
- Organizer
  第146回日本薬理学会関東部会
- Data Source
  KAKENHI-PROJECT-20K11512
[Presentation] シンポジウムS05生活習慣病研究の進展と創薬への展開：膵β細胞脂質代謝分子によるインスリン分泌制御および2型糖尿病病態形成への関与2021
- Author(s)
  金子雪子、石川智久
- Organizer
  日本薬学会第141年会
- Invited
- Data Source
  KAKENHI-PROJECT-20K11512
[Presentation] DIF-1, a differentiation-inducing factor from cellular slime mold, regulates transdifferentiation of hepatic stellate cells and ameliorates liver fibrosis2021
- Author(s)
  Akira Ooka, Nanami Motohashi, Momoka Yamaguchi, Sin-ya Saito, Tomohisa Ishikawa
- Organizer
  The 26th Shizuoka Forum on Health and Longevity
- Data Source
  KAKENHI-PROJECT-20H04110
[Presentation] DGKδ発現抑制による膵β細胞増殖機序の解析2021
- Author(s)
  渡邉直也、金子雪子、青島育美、大川里桜、石川揚子、石渡千裕、佐藤太治、石川智久
- Organizer
  日本薬学会第141年会
- Data Source
  KAKENHI-PROJECT-18K19755
[Presentation] 肝線維化責任細胞HSCのコラーゲン産生に対するharmineの作用およびその機序の解析2021
- Author(s)
  大岡央、山口桃生、大林彩、山下日菜子、本橋南菜実、金子雪子、木村俊秀、齊藤真也、石川智久
- Organizer
  第144回薬理学会関東部会
- Data Source
  KAKENHI-PROJECT-20H04110
[Presentation] 膵β細胞における妊娠期メラトニンシグナリング関連分子の発現および機能解析2021
- Author(s)
  一瀬健太朗、金子雪子、高橋夏実、八木雄也、石川智久
- Organizer
  第145回日本薬理学会関東部会
- Data Source
  KAKENHI-PROJECT-20K11512
[Presentation] 膵β細胞におけるエンドサイトーシス制御機構の解析2021
- Author(s)
  小寺聡史朗、木村俊秀、石川智久
- Organizer
  生体機能と創薬シンポジウム2021
- Data Source
  KAKENHI-PROJECT-20H04110
[Presentation] Comparative analysis of anti-diabetic effects of nobiletin and other citrus flavonoids on pancreatic β-cell function2021
- Author(s)
  Megumi Kaji, Yukiko Kaneko, Yuki Tara, Toshiyuki Kan, Tomohisa Ishikawa
- Organizer
  The 26th Shizuoka Forum on Health and Longevity
- Data Source
  KAKENHI-PROJECT-20K11512
[Presentation] アデノシン関連遺伝子の変化が炎症時において肝星細胞の活性化を促進する可能性2021
- Author(s)
  土肥直貴、山口桃生、齊藤真也、石川智久
- Organizer
  第94回日本薬理学会年会
- Data Source
  KAKENHI-PROJECT-20H04110
[Presentation] 膵β細胞におけるインスリン分泌制御機構の解析2021
- Author(s)
  小寺聡史朗、木村俊秀、石川智久
- Organizer
  第67回日本薬学会東海支部総会・大会
- Data Source
  KAKENHI-PROJECT-20H04110
[Presentation] アデノシン関連遺伝子の変化が炎症時において肝星細胞の活性化を促進する可能性2021
- Author(s)
  土肥直貴、山口桃生、齊藤真也、石川智久
- Organizer
  第94回日本薬理学会年会
- Data Source
  KAKENHI-PROJECT-18K19755
[Presentation] 肝障害ex vivoモデルを用いた肝疾患治療薬スクリーニング2021
- Author(s)
  髙橋亮汰、山口桃生、森野純鈴、本橋南菜実、大岡央、石川智久
- Organizer
  静岡実験動物研究会令和2-3年度大会
- Data Source
  KAKENHI-PROJECT-20H04110
[Presentation] 膵β細胞におけるジアシルグリセロールキナーゼζの発現と機能解析2021
- Author(s)
  渡邉直也、金子雪子、石川智久
- Organizer
  第145回日本薬理学会関東部会
- Data Source
  KAKENHI-PROJECT-20K11512
[Presentation] Comparative analysis of anti-diabetic effects of nobiletin and other citrus flavonoids on pancreatic β-cell function2021
- Author(s)
  Megumi Kaji, Yukiko Kaneko, Yuki Tara, Toshiyuki Kan, Tomohisa Ishikawa
- Organizer
  The 26th Shizuoka Forum on Health and Longevity
- Data Source
  KAKENHI-PROJECT-20H04110
[Presentation] DGKδ発現抑制による膵β細胞増殖機序の解析2021
- Author(s)
  渡邉直也、金子雪子、青島育美、大川里桜、石川揚子、石渡千裕、佐藤太治、石川智久
- Organizer
  日本薬学会第141年会
- Data Source
  KAKENHI-PROJECT-20H04110
[Presentation] 膵β細胞脂質代謝分子によるインスリン分泌制御および2型糖尿病病態形成への関与2021
- Author(s)
  金子雪子、石川智久
- Organizer
  日本薬学会第141年会
- Invited
- Data Source
  KAKENHI-PROJECT-20H04110
[Presentation] 膵β細胞脂質代謝分子によるインスリン分泌制御および2型糖尿病病態形成への関与2021
- Author(s)
  金子雪子、石川智久
- Organizer
  日本薬学会第141年会
- Invited
- Data Source
  KAKENHI-PROJECT-18K19755
[Presentation] 膵β細胞における、エンドサイトーシスの分子メカニズム解析2021
- Author(s)
  小寺聡史朗、木村俊秀、石川智久
- Organizer
  第44回日本分子生物学会年会
- Data Source
  KAKENHI-PROJECT-20H04110
[Presentation] 細胞性粘菌由来化合物DIF-1の肝線維化責任細胞HSCに対する脱活性化作用の解析および肝線維化モデルマウスに対する抗線維化作用の検証2021
- Author(s)
  本橋南菜実、大岡央、山口桃生、齊藤真也、石川智久
- Organizer
  第144回薬理学会関東部会
- Data Source
  KAKENHI-PROJECT-20H04110
[Presentation] 細胞性粘菌由来低分子化合物 DIF-1 は肝線維化責任細胞 HSC の活性化を制御し抗線維化作用を示す2021
- Author(s)
  本橋南菜実、大岡央、山口桃生、齊藤真也、濱島義隆、石川智久
- Organizer
  次世代を担う若手のための創薬・医療薬理シンポジウム2021
- Data Source
  KAKENHI-PROJECT-20H04110
[Presentation] DGKδ発現抑制による膵β細胞増殖機序の解析2021
- Author(s)
  渡邉直也、金子雪子、青島育美、大川里桜、石川揚子、石渡千裕、佐藤太治、石川智久
- Organizer
  日本薬学会第141年会
- Data Source
  KAKENHI-PROJECT-20K11512
[Presentation] 膵β細胞におけるエンドサイトーシス制御機構の解析2021
- Author(s)
  小寺聡史朗、木村俊秀、石川智久
- Organizer
  次世代を担う若手のための創薬・医療薬理シンポジウム2021
- Data Source
  KAKENHI-PROJECT-20H04110
[Presentation] 膵 β 細胞における妊娠期メラトニンシグナリング関連分子の発現および機能解析2021
- Author(s)
  一瀬健太朗、金子雪子、高橋夏実、八木雄也、石川智久
- Organizer
  第145回日本薬理学会関東部会
- Data Source
  KAKENHI-PROJECT-20H04110
[Presentation] 膵β細胞におけるInsulin receptor related receptor (IRR)の機能解析2021
- Author(s)
  伊藤慎悟、木村俊秀、石川智久
- Organizer
  第145回日本薬理学会関東部会
- Data Source
  KAKENHI-PROJECT-20H04110
[Presentation] 膵β細胞におけるジアシルグリセロールキナーゼζの発現と機能解析2021
- Author(s)
  渡邉直也、金子雪子、石川智久
- Organizer
  第145回日本薬理学会関東部会
- Data Source
  KAKENHI-PROJECT-20H04110
[Presentation] DGKδ機能抑制による膵β細胞増殖機序の解析2020
- Author(s)
  青島育美、金子雪子、石川揚子、木村悠希、松田有加里、石川智久
- Organizer
  日本薬学会　第140年会
- Data Source
  KAKENHI-PROJECT-17K01857
[Presentation] ノビレチンとその類縁体の膵β細胞機能に対する活性の比較研究2020
- Author(s)
  梶　萌、金子雪子、多良勇輝、山本萌絵、青柳有紀、秋山季理子、菅敏幸、石川智久
- Organizer
  第143回日本薬理学会関東部会
- Data Source
  KAKENHI-PROJECT-20H04110
[Presentation] ET-1による静止型肝星細胞の収縮に関わる分子メカニズムの解明2020
- Author(s)
  土肥直貴、山口桃生、長谷怜奈、鈴木良輔、若林夢人、齊藤真也、石川智久
- Organizer
  日本病院薬剤師会東海ブロック・日本薬学会東海支部合同学術大会2020
- Data Source
  KAKENHI-PROJECT-18K19755
[Presentation] 自律神経による肝臓の血流調節において肝星細胞が責任細胞となる可能性2020
- Author(s)
  土肥直貴、山口桃生、長谷怜奈、鈴木良輔、齊藤真也、石川智久
- Organizer
  第143回日本薬理学会関東部会
- Data Source
  KAKENHI-PROJECT-20H04110
[Presentation] ノビレチンとその類縁体の膵β細胞機能に対する活性の比較研究2020
- Author(s)
  梶　萌、金子雪子、多良勇輝、山本萌絵、青柳有紀、秋山季理子、菅敏幸、石川智久
- Organizer
  第143回日本薬理学会関東部会
- Data Source
  KAKENHI-PROJECT-20K11512
[Presentation] ET-1による静止型肝星細胞の収縮に関わる分子メカニズムの解明2020
- Author(s)
  土肥直貴、山口桃生、長谷怜奈、鈴木良輔、若林夢人、齊藤真也、石川智久
- Organizer
  日本病院薬剤師会東海ブロック・日本薬学会東海支部合同学術大会2020
- Data Source
  KAKENHI-PROJECT-20H04110
[Presentation] 低血糖副作用を回避する新規糖尿病治療薬の開発2020
- Author(s)
  藤田優香、南彰、金子雪子、澤谷俊明、大坪忠宗、池田潔、宮城妙子、紅林佑希、高橋忠伸、石川智久、鈴木隆
- Organizer
  第19回次世代を担う若手のためのファーマ・バイオフォーラム2020
- Data Source
  KAKENHI-PROJECT-20K11512
[Presentation] 自律神経による肝臓の血流調節において肝星細胞が責任細胞となる可能性2020
- Author(s)
  土肥直貴、山口桃生、長谷怜奈、鈴木良輔、齊藤真也、石川智久
- Organizer
  第143回日本薬理学会関東部会
- Data Source
  KAKENHI-PROJECT-18K19755
[Presentation] ノビレチンとその類縁体の膵β細胞機能に対する活性の比較研究2020
- Author(s)
  梶　萌、金子雪子、多良勇輝、山本萌絵、青柳有紀、秋山季理子、菅敏幸、石川智久
- Organizer
  第143回日本薬理学会関東部会
- Data Source
  KAKENHI-PROJECT-18K19755
[Presentation] ノビレチンはインスリン分泌促進および膵β細胞保護作用により糖尿病を改善させる2019
- Author(s)
  多良勇輝、金子雪子、山本萌絵、青柳有紀、秋山季里子、菅敏幸、石川智久
- Organizer
  日本薬学会第139年会
- Data Source
  KAKENHI-PROJECT-17K01857
[Presentation] Nobiletin は膵β細胞機能障害を抑制することで糖尿病改善効果を示す2019
- Author(s)
  梶　萌、金子雪子、多良勇輝、山本萌絵、青柳有紀、石川智久
- Organizer
  静岡実験動物研究会令和元年度大会第47回研究発表会
- Data Source
  KAKENHI-PROJECT-18K19755
[Presentation] ノビレチンはインスリン分泌促進および膵β細胞保護作用により糖尿病を改善させる2019
- Author(s)
  多良勇輝、金子雪子、山本萌絵、青柳有紀、秋山季理子、菅敏幸、石川智久
- Organizer
  日本薬学会第139年会
- Data Source
  KAKENHI-PROJECT-17H02175
[Presentation] Nobiletin は膵β細胞機能障害を抑制することで糖尿病改善効果を示す2019
- Author(s)
  梶　萌、金子雪子、多良勇輝、山本萌絵、青柳有紀、石川智久
- Organizer
  静岡実験動物研究会令和元年度大会第47回研究発表会
- Data Source
  KAKENHI-PROJECT-17H02175
[Presentation] 膵β細胞I型DGKの糖尿病下での発現と血糖調節への影響の解析2019
- Author(s)
  松浦　朋哉、金子雪子、芹澤　環、澤谷　俊明、白井　康仁、石川　智久
- Organizer
  第21回応用薬理シンポジウム
- Data Source
  KAKENHI-PROJECT-18K19755
[Presentation] 膵β細胞機能に対する柑橘類フラボノイドの作用2019
- Author(s)
  金子雪子、石川智久
- Organizer
  第92回日本薬理学会年会
- Invited
- Data Source
  KAKENHI-PROJECT-18K19755
[Presentation] 柑橘フラボノイドの膵β細胞に対する抗糖尿病効果の解析2019
- Author(s)
  梶　萌、金子雪子、多良勇輝、山本萌絵、青柳有紀、秋山季理子、石川智久
- Organizer
  第141回日本薬理学会関東部会
- Data Source
  KAKENHI-PROJECT-17H02175
[Presentation] Anti-diabetic effects of citrus flavonoids on pancreatic β-cell function.2019
- Author(s)
  金子雪子、石川智久
- Organizer
  第92回日本薬理学会年会
- Invited
- Data Source
  KAKENHI-PROJECT-17K01857
[Presentation] 膵β細胞機能に対する柑橘類フラボノイドの作用2019
- Author(s)
  金子雪子、石川智久
- Organizer
  第92回日本薬理学会年会
- Invited
- Data Source
  KAKENHI-PROJECT-17H02175
[Presentation] シンポジウム8 膵β細胞機能の新たなメッセンジャー：その生理と病態：Role of diacylglycerol kinase on the regulation of insulin secretion in pancreatic β-cells2019
- Author(s)
  金子雪子、澤谷俊明、石川智久
- Organizer
  第62回日本糖尿病学会年次学術集会
- Invited
- Data Source
  KAKENHI-PROJECT-17K01857
[Presentation] 膵β細胞機能に対するノビレチンの抗糖尿病活性効果の検討2019
- Author(s)
  梶萌、金子雪子、山本萌絵、石川智久
- Organizer
  第3回ノビレチン研究会
- Data Source
  KAKENHI-PROJECT-17H02175
[Presentation] DGKδ deficiency in mouse pancreatic β-cells alleviates STZ-induced diabetes.2019
- Author(s)
  木村悠希、金子雪子、中山貴寛、石川揚子、松田有加里、青島育美、石川智久
- Organizer
  第92回日本薬理学会年会
- Data Source
  KAKENHI-PROJECT-17K01857
[Presentation] DGKγ欠損による膵α細胞機能への影響の検討2019
- Author(s)
  芹澤環、金子雪子、戸倉広貴、松浦朋哉、澤谷俊明、石川智久
- Organizer
  第140回日本薬理学会関東部会
- Data Source
  KAKENHI-PROJECT-17K01857
[Presentation] 創薬シンポジウム３　新たな視点からの治療を指向した糖尿病研究の新潮流　細胞内脂質シグナリングによる膵β細胞量の制御、2019
- Author(s)
  金子雪子、石川智久
- Organizer
  生体機能と創薬シンポジウム2019
- Invited
- Data Source
  KAKENHI-PROJECT-17K01857
[Presentation] マウス膵β細胞におけるDGKδ欠損はSTZ誘発糖尿病を改善する2019
- Author(s)
  木村悠希、金子雪子、中山貴寛、石川揚子、松田有加里、青島育美、石川智久
- Organizer
  第92回日本薬理学会年会
- Data Source
  KAKENHI-PROJECT-18K19755
[Presentation] 膵β細胞機能に対するノビレチンの抗糖尿病活性効果の検討2019
- Author(s)
  金子雪子、石川智久
- Organizer
  第3回ノビレチン研究会
- Data Source
  KAKENHI-PROJECT-18K19755
[Presentation] 膵β細胞機能の新たなメッセンジャー：その生理と病態2019
- Author(s)
  金子雪子、澤谷俊明、石川智久
- Organizer
  第62回日本糖尿病学会年次学術集会
- Invited
- Data Source
  KAKENHI-PROJECT-17H02175
[Presentation] obiletin は膵β細胞機能障害を抑制することで糖尿病改善効果を示す2019
- Author(s)
  梶　萌、金子雪子、多良勇輝、山本萌絵、石川智久
- Organizer
  生体機能と創薬シンポジウム2019
- Data Source
  KAKENHI-PROJECT-18K19755
[Presentation] マウス膵β細胞におけるDGKδ欠損はSTZ誘発糖尿病を改善する2019
- Author(s)
  木村悠希、金子雪子、中山貴寛、石川揚子、松田有加里、青島育美、石川智久
- Organizer
  第92回日本薬理学会年会
- Data Source
  KAKENHI-PROJECT-17H02175
[Presentation] Nobiletin は膵β細胞機能障害を抑制することで糖尿病改善効果を示す2019
- Author(s)
  梶　萌、金子雪子、多良勇輝、山本萌絵、石川智久
- Organizer
  生体機能と創薬シンポジウム2019
- Data Source
  KAKENHI-PROJECT-17H02175
[Presentation] Diacylglycerol kinase: an intracellular regulator of insulin secretion from pancreatic β-cells2019
- Author(s)
  Tomohisa Ishikawa, Yukiko Kaneko
- Organizer
  KKU and University of Shizuoka joint symposium on medical and pharmaceutical sciences
- Invited / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-17H02175
[Presentation] 新たな視点からの治療を指向した糖尿病研究の新潮流　細胞内脂質シグナリングによる膵β細胞量の制御2019
- Author(s)
  金子雪子、石川智久
- Organizer
  生体機能と創薬シンポジウム2019
- Invited
- Data Source
  KAKENHI-PROJECT-18K19755
[Presentation] DGKγ欠損による膵α細胞機能への影響の検討2019
- Author(s)
  芹澤環、金子雪子、戸倉広貴、松浦朋哉、澤谷俊明、石川智久
- Organizer
  第140回日本薬理学会関東部会
- Data Source
  KAKENHI-PROJECT-18K19755
[Presentation] 膵β細胞I型DGKの糖尿病下での発現と血糖調節への影響の解析2019
- Author(s)
  松浦　朋哉、金子雪子、芹澤　環、澤谷　俊明、白井　康仁、石川　智久
- Organizer
  第21回応用薬理シンポジウム
- Data Source
  KAKENHI-PROJECT-17H02175
[Presentation] ノビレチンはインスリン分泌促進および膵β細胞保護作用により糖尿病を改善させる2019
- Author(s)
  多良勇輝、金子雪子、山本萌絵、青柳有紀、秋山季理子、菅敏幸、石川智久
- Organizer
  日本薬学会第139年会
- Data Source
  KAKENHI-PROJECT-18K19755
[Presentation] 膵β細胞機能に対するノビレチンの抗糖尿病活性効果の検討2019
- Author(s)
  金子雪子、石川智久
- Organizer
  第3回ノビレチン研究会
- Data Source
  KAKENHI-PROJECT-17H02175
[Presentation] 新たな視点からの治療を指向した糖尿病研究の新潮流　細胞内脂質シグナリングによる膵β細胞量の制御2019
- Author(s)
  金子雪子、石川智久
- Organizer
  生体機能と創薬シンポジウム2019
- Invited
- Data Source
  KAKENHI-PROJECT-17H02175
[Presentation] 膵β細胞機能に対するノビレチンの抗糖尿病活性効果の検討2019
- Author(s)
  梶萌、金子雪子、山本萌絵、石川智久
- Organizer
  第3回ノビレチン研究会
- Data Source
  KAKENHI-PROJECT-18K19755
[Presentation] Diacylglycerol kinase: an intracellular regulator of insulin secretion from pancreatic β-cells2019
- Author(s)
  Tomohisa Ishikawa, Yukiko Kaneko
- Organizer
  KKU and University of Shizuoka joint symposium on medical and pharmaceutical sciences
- Invited / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-18K19755
[Presentation] インスリン分泌後のエンドサイトーシス制御機構の解析2019
- Author(s)
  木村俊秀、山岡真美、石崎敏理、石川智久
- Organizer
  第140回日本薬理学会関東部会
- Data Source
  KAKENHI-PROJECT-18K19755
[Presentation] DGKγ欠損による膵α細胞機能への影響の検討2019
- Author(s)
  芹澤環、金子雪子、戸倉広貴、松浦朋哉、澤谷俊明、石川智久
- Organizer
  第140回日本薬理学会関東部会
- Data Source
  KAKENHI-PROJECT-17H02175
[Presentation] 柑橘フラボノイドの膵β細胞に対する抗糖尿病効果の解析2019
- Author(s)
  梶　萌、金子雪子、多良勇輝、山本萌絵、青柳有紀、秋山季理子、石川智久
- Organizer
  第141回日本薬理学会関東部会
- Data Source
  KAKENHI-PROJECT-18K19755
[Presentation] 膵β細胞機能の新たなメッセンジャー：その生理と病態2019
- Author(s)
  金子雪子、澤谷俊明、石川智久
- Organizer
  第62回日本糖尿病学会年次学術集会
- Invited
- Data Source
  KAKENHI-PROJECT-18K19755
[Presentation] 膵β細胞I型DGKの糖尿病下での発現と血糖調節への影響の解析2019
- Author(s)
  松浦　朋哉、金子雪子、芹澤　環、澤谷　俊明、白井　康仁、石川　智久
- Organizer
  第21回応用薬理シンポジウム
- Data Source
  KAKENHI-PROJECT-17K01857
[Presentation] インスリン分泌後のエンドサイトーシス制御機構の解析2019
- Author(s)
  木村俊秀、山岡真美、石崎敏理、石川智久
- Organizer
  第140回日本薬理学会関東部会
- Data Source
  KAKENHI-PROJECT-17H02175
[Presentation] 膵β細胞におけるDGKδ機能抑制による糖尿病病態改善効果とそのメカニズムの解析2018
- Author(s)
  松田有加里、金子雪子、木村悠希、石川揚子、中山貴寛、石川智久
- Organizer
  日本病院薬剤師会東海ブロック・日本薬学会東海支部合同学術大会 2018
- Data Source
  KAKENHI-PROJECT-18K19755
[Presentation] Effects of citrus flavonoids on pancreatic β-cell function.2018
- Author(s)
  Yuki Tara, Yukiko K. Kaneko, Moe Yamamoto, Yuki Aoyagi, Megumi Kaji, Kiriko Akiyama, Toshiyuki Kan, and Tomohisa Ishikawa
- Organizer
  The 4th　International Conference on Pharma and Food
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-17K01857
[Presentation] DAG accumulation due to type 1 DGK inhibition has contradictory dual effect on Ca2+ signaling in pancreatic β cells2018
- Author(s)
  Toshiaki Sawatani, Yukiko Kaneko, Tomohisa Ishikawa
- Organizer
  American Diabetes Association 78th Scientific Sessions
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-18K19755
[Presentation] DGKδ deficiency in mouse pancreatic β-cells improves STZ-induced hyperglycemia.2018
- Author(s)
  Yuki Kimura, Yukiko Kaneko, Taiji Sato, Chihiro Ishiwatari, Yoko Ishikawa, Yukari Matsuda, Tomohisa Ishikawa.
- Organizer
  The 4th International Conference on Pharma and Food
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-17K01857
[Presentation] 膵β細胞量増加を目指した新規糖尿病治療創薬標的としての膵β細胞脂質代謝制御、一般シンポジウムS70　若手が取り組む新規糖尿病治療・予防法の開発を目指した研究戦略2018
- Author(s)
  金子雪子、石川智久
- Organizer
  日本薬学会第138年会
- Invited
- Data Source
  KAKENHI-PROJECT-17K01857
[Presentation] Diacylglycerol accumulation due to type-1 diacylglycerol kinase dysfunction has a dual response on insulin secretion in pancreatic β-cells2018
- Author(s)
  Toshiaki Sawatani, Yukiko Kaneko, Tomohisa Ishikawa
- Organizer
  The 4th International Conference on Pharma and Food
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-18K19755
[Presentation] TRPV2 channels mediate cell swelling-induced insulin secretion in mouse pancreatic β cells.2018
- Author(s)
  Toshiaki Sawatani, Yukiko Kaneko, Isao Doutsu, Ai Ogawa, Tomohisa Ishikawa
- Organizer
  18th World Congress of Basic and Clinical Pharmacology
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-17H02175
[Presentation] 膵β細胞におけるメラトニンシグナリング関連分子の発現および機能解析2018
- Author(s)
  八木雄也、金子雪子、鴨志田ありさ、石川智久
- Organizer
  日本病院薬剤師会東海ブロック・日本薬学会東海支部合同学術大会 2018
- Data Source
  KAKENHI-PROJECT-18K19755
[Presentation] 膵β細胞におけるDGKδ機能抑制による糖尿病病態改善効果とそのメカニズムの解析2018
- Author(s)
  松田有加里、金子雪子、木村悠希、石川揚子、中山貴寛、石川智久
- Organizer
  日本病院薬剤師会東海ブロック・日本薬学会東海支部合同学術大会2018
- Data Source
  KAKENHI-PROJECT-17K01857
[Presentation] 膵β細胞においてI型ジアシルグリセロールキナーゼ機能低下はインスリン分泌を二面性に制御する2018
- Author(s)
  澤谷俊明、金子雪子、石川智久
- Organizer
  生体機能と創薬シンポジウム2018
- Data Source
  KAKENHI-PROJECT-17H02175
[Presentation] 糖尿病下における細胞内ADMAの蓄積はNOによる膵β細胞保護作用を減弱させる2018
- Author(s)
  佐野実咲、金子雪子、森岡亜望、石川智久
- Organizer
  日本薬学会第138年会
- Data Source
  KAKENHI-PROJECT-17H02175
[Presentation] β細胞におけるDGKδ機能抑制による細胞増殖および糖尿病病態への効果の解析2018
- Author(s)
  木村悠希、金子雪子、石川揚子、中山貴寛、石川智久
- Organizer
  第61回日本糖尿病学会年次学術集会
- Data Source
  KAKENHI-PROJECT-17K01857
[Presentation] Contribution of TRPV2 channels in cell swelling-induced insulin secretion in mouse pancreatic β-cells.2018
- Author(s)
  Toshiaki Sawatani, Yukiko K. Kaneko, Isao Dotsu, Ai Ogawa and Tomohisa Ishikawa
- Organizer
  The 23rd Shizuoka Forum on Health and Longevity
- Data Source
  KAKENHI-PROJECT-17K01857
[Presentation] β細胞におけるDGKδ機能抑制による細胞増殖および糖尿病病態への効果の解析2018
- Author(s)
  木村悠希、金子雪子、石川揚子、中山貴寛、石川智久
- Organizer
  第60回日本糖尿病学会年次学術集会
- Data Source
  KAKENHI-PROJECT-18K19755
[Presentation] 膵β細胞における柑橘類果皮抽出成分ノビレチンの抗糖尿病効果の解析2018
- Author(s)
  青柳有紀、金子雪子、秋山季里子、多良勇輝、山本萌絵、石川智久
- Organizer
  第138回日本薬理学会関東部会
- Data Source
  KAKENHI-PROJECT-17K01857
[Presentation] 膵β細胞概日リズム形成に関わる分子の発現および機能解析2018
- Author(s)
  鴨志田ありさ、金子雪子、八木雄也、中村哲、石川智久
- Organizer
  第138回日本薬理学会関東部会
- Data Source
  KAKENHI-PROJECT-17K01857
[Presentation] 糖尿病下における細胞内ADMAの蓄積はNOによる膵β細胞保護作用を減弱させる2018
- Author(s)
  佐野実咲、金子雪子、森岡亜望、石川智久
- Organizer
  日本薬学会第138年会
- Data Source
  KAKENHI-PROJECT-15K12705
[Presentation] 膵β細胞機能に対する柑橘類フラボノイドの作用2018
- Author(s)
  金子雪子、石川智久
- Organizer
  第92回日本薬理学会年会
- Data Source
  KAKENHI-PROJECT-17H02175
[Presentation] 膵β細胞におけるDGKαおよびγ機能抑制によるDAG蓄積は細胞内Ca2+濃度に対して二面性を示す2018
- Author(s)
  澤谷俊明、金子雪子、石川智久
- Organizer
  第60回日本糖尿病学会年次学術集会
- Data Source
  KAKENHI-PROJECT-17H02175
[Presentation] DAG accumulation due to type 1 DGK inhibition has contradictory dual effect on Ca2+ signaling in pancreatic β cells2018
- Author(s)
  Toshiaki Sawatani, Yukiko Kaneko, Tomohisa Ishikawa
- Organizer
  American Diabetes Association 78th Scientific Sessions
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-17H02175
[Presentation] 膵β細胞におけるDGKαおよびγ機能抑制によるDAG蓄積は細胞内Ca2+濃度に対して二面性を示す2018
- Author(s)
  澤谷俊明、金子雪子、石川智久
- Organizer
  第61回日本糖尿病学会年次学術集会
- Data Source
  KAKENHI-PROJECT-17K01857
[Presentation] 膵β細胞におけるDGKαおよびγ機能抑制によるDAG蓄積は細胞内Ca2+濃度に対して二面性を示す2018
- Author(s)
  澤谷俊明、金子雪子、石川智久
- Organizer
  第60回日本糖尿病学会年次学術集会
- Data Source
  KAKENHI-PROJECT-18K19755
[Presentation] 膵β細胞概日リズム形成に関わる分子の発現および機能解析2018
- Author(s)
  鴨志田ありさ、金子雪子、八木雄也、中村哲、石川智久
- Organizer
  第138回日本薬理学会関東部会
- Data Source
  KAKENHI-PROJECT-17H02175
[Presentation] Effects of citrus flavonoids on pancreatic β-cell function2018
- Author(s)
  Yuki Tara, Yukiko Kaneko, Yuki Aoyagi, Megumi Kaji, Kiriko Akiyama, Toshiyuki Kan, Tomohisa Ishikawa
- Organizer
  The 4th International Conference on Pharma and Food
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-17H02175
[Presentation] Diacylglycerol accumulation due to type-1 diacylglycerol kinase dysfunction has a dual response on insulin secretion in pancreatic β-cells2018
- Author(s)
  Toshiaki Sawatani, Yukiko Kaneko, Tomohisa Ishikawa
- Organizer
  The 4th International Conference on Pharma and Food
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-17H02175
[Presentation] 膵β細胞におけるメラトニンシグナリング関連分子の発現および機能解析2018
- Author(s)
  八木雄也、金子雪子、鴨志田ありさ、石川智久
- Organizer
  日本病院薬剤師会東海ブロック・日本薬学会東海支部合同学術大会 2018
- Data Source
  KAKENHI-PROJECT-17H02175
[Presentation] β細胞におけるDGKδ機能抑制による細胞増殖および糖尿病病態への効果の解析2018
- Author(s)
  木村悠希、金子雪子、石川揚子、中山貴寛、石川智久
- Organizer
  第60回日本糖尿病学会年次学術集会
- Data Source
  KAKENHI-PROJECT-17H02175
[Presentation] Modulation of DDAH/ADMA/NOS pathway in pancreatic β-cells under diabetic condition.2018
- Author(s)
  Yukiko K. Kaneko, Misaki Sano, Ami Morioka, Masato Nojiri, Nahoko Kasahara, Tomohisa Ishikawa
- Organizer
  18th World Congress of Basic and Clinical Pharmacology
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-17K01857
[Presentation] 膵β細胞においてI型ジアシルグリセロールキナーゼ機能低下はインスリン分泌を二面性に制御する2018
- Author(s)
  澤谷俊明、金子雪子、石川智久
- Organizer
  生体機能と創薬シンポジウム2018
- Data Source
  KAKENHI-PROJECT-18K19755
[Presentation] 膵β細胞におけるDGKδ機能抑制による糖尿病病態改善効果とそのメカニズムの解析2018
- Author(s)
  松田有加里、金子雪子、木村悠希、石川揚子、中山貴寛、石川智久
- Organizer
  日本病院薬剤師会東海ブロック・日本薬学会東海支部合同学術大会 2018
- Data Source
  KAKENHI-PROJECT-17H02175
[Presentation] ノビレチンはインスリン分泌促進および膵β細胞保護作用により糖尿病を改善させる2018
- Author(s)
  多良勇輝、金子雪子、山本萌絵、青柳有紀、秋山季理子、菅敏幸、石川智久
- Organizer
  日本薬学会第139年会
- Data Source
  KAKENHI-PROJECT-17H02175
[Presentation] 糖尿病下における細胞内ADMAの蓄積はNOによる膵β細胞保護作用を減弱させる2018
- Author(s)
  佐野実咲、金子雪子、森岡亜望、石川智久
- Organizer
  日本薬学会第138年会
- Data Source
  KAKENHI-PROJECT-17K01857
[Presentation] 膵β細胞における柑橘果皮抽出成分ノビレチンの抗糖尿病効果の解析2018
- Author(s)
  青柳有紀、金子雪子、秋山季里子、多良勇輝、山本萌絵、石川智久
- Organizer
  第138回日本薬理学会関東部会
- Data Source
  KAKENHI-PROJECT-15K12705
[Presentation] 膵β細胞における柑橘果皮抽出成分ノビレチンの抗糖尿病効果の解析2018
- Author(s)
  青柳有紀、金子雪子、秋山季里子、多良勇輝、山本萌絵、石川智久
- Organizer
  第138回日本薬理学会関東部会
- Data Source
  KAKENHI-PROJECT-17H02175
[Presentation] Diacylglycerol accumulation due to type-1 diacylglycerol kinase dysfunction has a dual response on insulin secretion in pancreatic β-cells.2018
- Author(s)
  Toshiaki Sawatani, Yukiko K. Kaneko and Tomohisa Ishikawa
- Organizer
  The 4th International Conference on Pharma and Food
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-17K01857
[Presentation] DAG accumulation due to type 1 DGK inhibition has a contradictory dual effect on Ca2+ signaling in pancreatic β-cells.2018
- Author(s)
  Toshiaki Sawatani, Yukiko Kaneko, Tomohisa Ishikawa.
- Organizer
  American Diabetes Association Scientific Sessions 2018
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-17K01857
[Presentation] TRPV2 channels mediate cell swelling-induced insulin secretion in mouse pancreatic β cells.2018
- Author(s)
  Toshiaki Sawatani, Yukiko Kaneko, Isao Doutsu, Ai Ogawa, Tomohisa Ishikawa
- Organizer
  18th World Congress of Basic and Clinical Pharmacology
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-18K19755
[Presentation] DGKδ deficiency in mouse pancreatic β-cells improves STZ-induced hyperglycemia2018
- Author(s)
  Yuki Kimura, Yukiko Kaneko, Taiji Sato, Chihiro Ishiwatari, Yoko Ishikawa, Yukari Matsuda, Tomohisa Ishikawa
- Organizer
  The 4th International Conference on Pharma and Food
- Data Source
  KAKENHI-PROJECT-17H02175
[Presentation] 植物ポリフェノールの膵β細胞機能に対する効果の解析2018
- Author(s)
  山本萌絵、金子雪子、多良勇輝、青柳有紀、秋山季理子、菅敏幸、石川智久
- Organizer
  日本病院薬剤師会東海ブロック・日本薬学会東海支部合同学術大会 2018
- Data Source
  KAKENHI-PROJECT-17H02175
[Presentation] Modulation of DDAH/ADMA/NOS pathway in pancreatic β-cells under diabetic condition.2018
- Author(s)
  Yukiko Y Kaneko, Misaki Sano, Ami Morioka, Masato Nojiri, Nahoko Kasahara, Tomohisa Ishikawa
- Organizer
  18th World Congress of Basic and Clinical Pharmacology
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-18K19755
[Presentation] Effects of citrus flavonoids on pancreatic β-cell function2018
- Author(s)
  Yuki Tara, Yukiko Kaneko, Yuki Aoyagi, Megumi Kaji, Kiriko Akiyama, Toshiyuki Kan, Tomohisa Ishikawa
- Organizer
  The 4th International Conference on Pharma and Food
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-18K19755
[Presentation] 膵β細胞概日リズム形成に関わる分子の発現および機能解析2018
- Author(s)
  鴨志田ありさ、金子雪子、八木雄也、中村哲、石川智久
- Organizer
  第138回日本薬理学会関東部会
- Data Source
  KAKENHI-PROJECT-15K12705
[Presentation] マウス膵β細胞におけるDGKδ欠損はSTZ誘発糖尿病を改善する2018
- Author(s)
  木村悠希、金子雪子、中山貴寛、石川揚子、松田有加里、青島育美、石川智久
- Organizer
  第92回日本薬理学会年会
- Data Source
  KAKENHI-PROJECT-18K19755
[Presentation] ノビレチンはインスリン分泌促進および膵β細胞保護作用により糖尿病を改善させる2018
- Author(s)
  多良勇輝、金子雪子、山本萌絵、青柳有紀、秋山季理子、菅敏幸、石川智久
- Organizer
  日本薬学会第139年会
- Data Source
  KAKENHI-PROJECT-18K19755
[Presentation] TRPV2 channels mediate cell swelling-induced insulin secretion in mouse pancreatic β-cells.2018
- Author(s)
  Toshiaki Sawatani, Yukiko K. Kaneko, Tomohisa Ishikawa.
- Organizer
  18th World Congress of Basic and Clinical Pharmacology
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-17K01857
[Presentation] マウス膵β細胞におけるDGKδ欠損はSTZ誘発糖尿病を改善する2018
- Author(s)
  木村悠希、金子雪子、中山貴寛、石川揚子、松田有加里、青島育美、石川智久
- Organizer
  第92回日本薬理学会年会
- Data Source
  KAKENHI-PROJECT-17H02175
[Presentation] 膵β細胞においてI型ジアシルグリセロールキナーゼ機能低下はインスリン分泌を二面性に制御する2018
- Author(s)
  澤谷俊明、金子雪子、石川智久
- Organizer
  生体機能と創薬シンポジウム2018
- Data Source
  KAKENHI-PROJECT-17K01857
[Presentation] 膵β細胞機能に対する柑橘類フラボノイドの作用2018
- Author(s)
  金子雪子、石川智久
- Organizer
  第92回日本薬理学会年会
- Data Source
  KAKENHI-PROJECT-18K19755
[Presentation] Modulation of DDAH/ADMA/NOS pathway in pancreatic β-cells under diabetic condition.2018
- Author(s)
  Yukiko Y Kaneko, Misaki Sano, Ami Morioka, Masato Nojiri, Nahoko Kasahara, Tomohisa Ishikawa
- Organizer
  18th World Congress of Basic and Clinical Pharmacology
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-17H02175
[Presentation] 植物ポリフェノールの膵β細胞機能に対する効果の解析2018
- Author(s)
  山本萌絵、金子雪子、多良勇輝、青柳有紀、秋山季理子、菅敏幸、石川智久
- Organizer
  日本病院薬剤師会東海ブロック・日本薬学会東海支部合同学術大会 2018
- Data Source
  KAKENHI-PROJECT-18K19755
[Presentation] DGKδ deficiency in mouse pancreatic β-cells improves STZ-induced hyperglycemia2018
- Author(s)
  Yuki Kimura, Yukiko Kaneko, Taiji Sato, Chihiro Ishiwatari, Yoko Ishikawa, Yukari Matsuda, Tomohisa Ishikawa
- Organizer
  The 4th International Conference on Pharma and Food
- Data Source
  KAKENHI-PROJECT-18K19755
[Presentation] 膵β細胞TRPV2活性化は細胞膨張誘発インスリン分泌反応に関与する2017
- Author(s)
  澤谷俊明、金子雪子、石川智久
- Organizer
  第136回日本薬理学会関東部会
- Data Source
  KAKENHI-PROJECT-17H02175
[Presentation] 膵β細胞TRPV2活性化は細胞膨張誘発インスリン分泌反応に関与する2017
- Author(s)
  澤谷俊明、金子雪子、石川智久
- Organizer
  第136回日本薬理学会関東部会
- Data Source
  KAKENHI-PROJECT-17K01857
[Presentation] Contradictory dual effect of type I diacylglycerol kinase dysfunction on intracellular Ca2+ signaling in pancreatic β cells2017
- Author(s)
  Toshiaki Sawatani, Yukiko Kaneko, Tomohisa Ishikawa
- Organizer
  第90回日本薬理学会年会
- Place of Presentation
  長崎
- Year and Date
  2017-03-16
- Data Source
  KAKENHI-PROJECT-15K12705
[Presentation] マウス膵β細胞におけるDGKδ発現抑制によりSTZ誘発糖尿病は改善する2017
- Author(s)
  石川揚子、金子雪子、中山貴寛、木村悠希、石川智久
- Organizer
  次世代を担う創薬・医療薬理シンポジウム2017
- Data Source
  KAKENHI-PROJECT-17K01857
[Presentation] Inhibition of Type I DGK leads to a dual response on Ca2+ signaling in pancreatic β-cells2017
- Author(s)
  Toshiaki Sawatani, Yukiko Kaneko, Tomohisa Ishikawa
- Organizer
  International Symposium on Calcium Binding Proteins and Calcium Function in Health and Disease
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-15K12705
[Presentation] 膵β細胞におけるDGKαおよびγ機能抑制は細胞内Ca2+濃度に対して二面的作用を示す2017
- Author(s)
  澤谷俊明、金子雪子、石川智久
- Organizer
  次世代を担う創薬・医療薬理シンポジウム2017
- Data Source
  KAKENHI-PROJECT-17K01857
[Presentation] Role of DGKs in the regulation of insulin secretion and β-cell mass2017
- Author(s)
  Tomohisa Ishikawa, Yukiko Kaneko
- Organizer
  The 7th DGK international mini symposium
- Place of Presentation
  神戸
- Year and Date
  2017-03-13
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-15K12705
[Presentation] 膵β細胞において細胞膨張によるTRPV2活性化はインスリン分泌反応を惹起する．2017
- Author(s)
  澤谷俊明、金子雪子、石川智久
- Organizer
  生体機能と創薬シンポジウム2017
- Data Source
  KAKENHI-PROJECT-17K01857
[Presentation] 膵β細胞における細胞膨張誘発インスリン分泌反応にはTRPV2活性化が関与する2017
- Author(s)
  澤谷俊明、金子雪子、石川智久
- Organizer
  第60回日本糖尿病学会年次学術集会
- Data Source
  KAKENHI-PROJECT-17H02175
[Presentation] 糖尿病下における内因性NOS阻害物質の蓄積は膵β細胞障害を亢進させる2017
- Author(s)
  佐野実咲、金子雪子、森岡亜望、石川智久
- Organizer
  第136回日本薬理学会関東部会
- Data Source
  KAKENHI-PROJECT-15K12705
[Presentation] 膵β細胞におけるNO産生調節系と2型糖尿病病態との関係2017
- Author(s)
  石川智久、森岡亜望、佐野実咲、金子雪子
- Organizer
  生理学研究所研究会2017
- Data Source
  KAKENHI-PROJECT-17H02175
[Presentation] Diacylglycerol kinase δ deficiency in mice pancreatic β-cells leads to improvement of streptozotocin-induced diabetes2017
- Author(s)
  石川揚子、金子雪子、中山貴寛、木村悠希、石川智久
- Organizer
  次世代を担う創薬・医療薬理シンポジウム2017
- Data Source
  KAKENHI-PROJECT-17H02175
[Presentation] 糖尿病下における内因性NOS阻害物質の蓄積は膵β細胞障害を亢進させる2017
- Author(s)
  佐野実咲、金子雪子、森岡亜望、石川智久
- Organizer
  第136回日本薬理学会関東部会
- Data Source
  KAKENHI-PROJECT-17K01857
[Presentation] TRPV2活性化は膵β細胞における細胞膨張誘発性インスリン分泌反応に関与する2017
- Author(s)
  澤谷俊明、金子雪子、石川智久
- Organizer
  日本薬学会第137年会
- Place of Presentation
  仙台
- Year and Date
  2017-03-26
- Data Source
  KAKENHI-PROJECT-15K12705
[Presentation] 膵β細胞において細胞膨張によるTRPV2活性化はインスリン分泌反応を惹起する2017
- Author(s)
  澤谷俊明、金子雪子、石川智久
- Organizer
  生体機能と創薬シンポジウム2017
- Data Source
  KAKENHI-PROJECT-17H02175
[Presentation] 膵β細胞におけるNO産生調節系と2型糖尿病病態との関係2017
- Author(s)
  石川智久、森岡亜望、佐野実咲、金子雪子
- Organizer
  生理学研究所研究会2017
- Data Source
  KAKENHI-PROJECT-15K12705
[Presentation] 膵β細胞における細胞膨張誘発インスリン分泌反応にはTRPV2活性化が関与する2017
- Author(s)
  澤谷俊明、金子雪子、石川智久
- Organizer
  第60回日本糖尿病学会年次学術集会
- Data Source
  KAKENHI-PROJECT-17K01857
[Presentation] Diacylglycerol kinase δ deficiency in mice pancreatic β-cells leads to improvement of streptozotocin-induced diabetes2017
- Author(s)
  石川揚子、金子雪子、中山貴寛、木村悠希、石川智久
- Organizer
  次世代を担う創薬・医療薬理シンポジウム2017
- Data Source
  KAKENHI-PROJECT-15K12705
[Presentation] Inhibition of Type I DGK Leads to a Dual Response on Ca2+ Signaling in Pancreatic β-Cells.2017
- Author(s)
  Toshiaki Sawatani, Yukiko Kaneko, Tomohisa Ishikawa
- Organizer
  20th International Sympoium on Calcium Binding Proteins and Calsium Function in Health and Disease (CaBP20)
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-17K01857
[Presentation] 膵β細胞において細胞膨張によるTRPV2活性化はインスリン分泌反応を惹起する2017
- Author(s)
  澤谷俊明、金子雪子、石川智久
- Organizer
  生体機能と創薬シンポジウム2017
- Data Source
  KAKENHI-PROJECT-15K12705
[Presentation] ストレプトゾトシン誘発糖尿病モデルマウスにおける膵β細胞ジアシルグリセロールキナーゼδ欠損の影響2017
- Author(s)
  中山貴寛、金子雪子、佐藤太治、石渡千裕、石川揚子、木村悠希、石川智久
- Organizer
  日本薬学会第137年会
- Place of Presentation
  仙台
- Year and Date
  2017-03-26
- Data Source
  KAKENHI-PROJECT-15K12705
[Presentation] 膵β細胞における細胞膨張誘発インスリン分泌反応にはTRPV2活性化が関与する2017
- Author(s)
  澤谷俊明、金子雪子、石川智久
- Organizer
  第60回日本糖尿病学会年次学術集会
- Data Source
  KAKENHI-PROJECT-15K12705
[Presentation] Inhibition of Type I DGK leads to a dual response on Ca2+ signaling in pancreatic β-cells2017
- Author(s)
  Toshiaki Sawatani, Yukiko Kaneko, Tomohisa Ishikawa
- Organizer
  International Symposium on Calcium Binding Proteins and Calcium Function in Health and Disease
- Data Source
  KAKENHI-PROJECT-17H02175
[Presentation] 膵β細胞におけるDGKαおよびγ機能抑制は細胞内Ca2+濃度に対して二面的作用を示す2017
- Author(s)
  澤谷俊明、金子雪子、石川智久
- Organizer
  次世代を担う創薬・医療薬理シンポジウム2017
- Data Source
  KAKENHI-PROJECT-17H02175
[Presentation] 膵β細胞におけるDGKαおよびγ機能抑制は細胞内Ca2+濃度に対して二面的作用を示す2017
- Author(s)
  澤谷俊明、金子雪子、石川智久
- Organizer
  次世代を担う創薬・医療薬理シンポジウム2017
- Data Source
  KAKENHI-PROJECT-15K12705
[Presentation] 糖尿病下における内因性NOS阻害物質の蓄積は膵β細胞障害を亢進させる2017
- Author(s)
  佐野実咲、金子雪子、森岡亜望、石川智久
- Organizer
  第136回日本薬理学会関東部会
- Data Source
  KAKENHI-PROJECT-17H02175
[Presentation] 膵β細胞TRPV2活性化は細胞膨張誘発インスリン分泌反応に関与する2017
- Author(s)
  澤谷俊明、金子雪子、石川智久
- Organizer
  第136回日本薬理学会関東部会
- Data Source
  KAKENHI-PROJECT-15K12705
[Presentation] Nobiletin promotes insulin secretion and prevents β-cell apoptosis through a cAMP dependent pathway2016
- Author(s)
  Yukiko Kaneko, Tomohisa Ishikawa
- Organizer
  The 3rd　International Conference on Pharma and Food
- Place of Presentation
  静岡
- Year and Date
  2016-11-17
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-15K12705
[Presentation] 膵β細胞におけるⅠ型ジアシルグリセロールキナーゼの機能抑制は細胞内Ca2+濃度に対して二面性を示す2016
- Author(s)
  澤谷俊明、金子雪子、石川智久
- Organizer
  第135回日本薬理学会関東部会
- Place of Presentation
  浜松
- Year and Date
  2016-10-08
- Data Source
  KAKENHI-PROJECT-15K12705
[Presentation] Involvement of TRPV2 in cell swelling-induced insulin secretion in mouse pancreatic β-cells2016
- Author(s)
  Toshiaki Sawatani, Yukiko Kaneko, Tomohisa Ishikawa
- Organizer
  The 3rd　International Conference on Pharma and Food
- Place of Presentation
  静岡
- Year and Date
  2016-11-17
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-15K12705
[Presentation] 膵β細胞機能に対する柑橘果皮成分ノビレチンの作用解析2016
- Author(s)
  秋山季里子、金子雪子、瀧井美樹、青柳有紀、石川智久
- Organizer
  第135回日本薬理学会関東部会
- Place of Presentation
  浜松
- Year and Date
  2016-10-08
- Data Source
  KAKENHI-PROJECT-15K12705
[Presentation] I型ジアシルグリセロールキナーゼ機能阻害によるインスリン分泌抑制機序の解明と2型糖尿病病態との関連2016
- Author(s)
  澤谷俊明、金子雪子、石川智久
- Organizer
  第59回日本糖尿病学会年次学術集会
- Place of Presentation
  京都
- Year and Date
  2016-05-21
- Data Source
  KAKENHI-PROJECT-15K12705
[Presentation] ジアシルグリセロールキナーゼδは膵β細胞増殖を抑制性に制御する分子である2016
- Author(s)
  金子雪子、佐藤太治、石渡千裕、中山貴寛、石川揚子、石川智久
- Organizer
  第59回日本糖尿病学会年次学術集会
- Place of Presentation
  京都
- Year and Date
  2016-05-19
- Data Source
  KAKENHI-PROJECT-15K12705
[Presentation] 膵β細胞におけるジアシルグリセロールキナーゼδの発現・機能解析2015
- Author(s)
  18.石渡千裕、金子雪子、佐藤太治、中山貴寛、石川揚子、千葉里菜、藤貫貴大、石川智
- Organizer
  次世代を担う創薬・医療薬理シンポジウム2015
- Place of Presentation
  神戸
- Year and Date
  2015-08-29
- Data Source
  KAKENHI-PROJECT-15K12705
[Presentation] 膵β細胞におけるジアシルグリセロールキナーゼδの役割の解明2015
- Author(s)
  18.石渡千裕、金子雪子、佐藤太治、中山貴寛、石川揚子、千葉里菜、藤貫貴大、石川智久
- Organizer
  第133回日本薬理学会関東部会
- Place of Presentation
  柏
- Year and Date
  2015-10-10
- Data Source
  KAKENHI-PROJECT-15K12705
[Presentation] Functional role of diacylglycerol kinase δ in pancreatic β-cells.2015
- Author(s)
  金子雪子、佐藤太治、石渡千裕、中山貴寛、石川智久
- Organizer
  第38回日本分子生物学会年会、第88回日本生化学会大会合同大会
- Place of Presentation
  神戸
- Year and Date
  2015-12-02
- Invited
- Data Source
  KAKENHI-PROJECT-15K12705
[Presentation] 膵β細胞におけるADMAを介したNO産生調節機構と糖尿病病態への関与2015
- Author(s)
  森岡亜望、金子雪子、石川智久
- Organizer
  第61回日本薬学会東海支部大会
- Place of Presentation
  名古屋
- Year and Date
  2015-07-04
- Data Source
  KAKENHI-PROJECT-15K12705
[Presentation] 皮膚血管におけるα1受容体を介した収縮機構の違い2014
- Author(s)
  石田裕丈、菱沼瑛多、北川智章、斉藤真也、石川智久
- Organizer
  日本薬学会第134年会
- Place of Presentation
  熊本
- Data Source
  KAKENHI-PROJECT-23590192
[Presentation] 心機能調節におけるジアシルグリセロールキナーゼの役割2014
- Author(s)
  植木桂一郎、齊藤真也、石川智久
- Organizer
  日本薬学会第134年会
- Place of Presentation
  熊本
- Data Source
  KAKENHI-PROJECT-23590192
[Presentation] Type I　ジアシルグリセロールキナーゼはインスリン分泌を促進性に制御する脂質シグナル調節分子である2014
- Author(s)
  宮川昌子、金子雪子、元木啓介、小林洋輔、石川智久
- Organizer
  日本薬学会第134年会
- Place of Presentation
  熊本
- Data Source
  KAKENHI-PROJECT-23590192
[Presentation] アシル化ブテノリドはMYPT1のリン酸化抑制によって平滑筋の収縮を阻害する2014
- Author(s)
  増田真也、伊藤誓悟、金井慧、齊藤真也、菊地晴久、大島吉輝、石川智久
- Organizer
  第87回日本薬理学会年会
- Place of Presentation
  仙台
- Data Source
  KAKENHI-PROJECT-23590192
[Presentation] 雌性マウスにおける局所冷却誘発皮膚血流減少反応へのエストロゲンの影響2014
- Author(s)
  岩崎希、芹澤いづみ、石川智久
- Organizer
  日本薬学会第134年会
- Place of Presentation
  熊本
- Data Source
  KAKENHI-PROJECT-23590192
[Presentation] 糖尿病病態における構成型NOS由来NOにより膵β細胞機能調節の変化2012
- Author(s)
  石川智久、金子雪子
- Organizer
  病態生理シンポジウムII「糖代謝の病態生理学」第22回日本病態生理学会
- Place of Presentation
  大分
- Year and Date
  2012-08-04
- Data Source
  KAKENHI-PROJECT-23590192
[Presentation] 膵β細胞における構成型NO合成酵素(cNOS)活性調節に対する高血糖の影響2012
- Author(s)
  金子雪子、野尻雅人、笠原七帆子、石川智久
- Organizer
  第126回日本薬理学会関東部会
- Place of Presentation
  東京
- Year and Date
  2012-07-14
- Data Source
  KAKENHI-PROJECT-23590192
[Presentation] 膵β細胞におけるDDAH/ADMA/NOS経路を介したNO産生調節機構の解析2012
- Author(s)
  野尻雅人、金子雪子、笠原七帆子、石川智久
- Organizer
  第58回日本薬学会東海支部総会・大会
- Place of Presentation
  静岡
- Year and Date
  2012-07-07
- Data Source
  KAKENHI-PROJECT-23590192
[Presentation] 糖尿病病態における構成型NOS由来NOにより膵β細胞機能調節の変化2012
- Author(s)
  石川智久
- Organizer
  第22回日本病態生理学会
- Place of Presentation
  大分
- Invited
- Data Source
  KAKENHI-PROJECT-23590192
[Presentation] 構成型NOS由来NOによる膵β細胞機能調節と糖尿病との関係2011
- Author(s)
  石川智久
- Organizer
  日本薬学会第131年会
- Place of Presentation
  静岡
- Year and Date
  2011-03-29
- Data Source
  KAKENHI-PROJECT-20590085
[Presentation] Ca^<2+>-dependent mechanism for hydrogen peroxide-induced apoptosis in pancreatic β-cells.2010
- Author(s)
 Sayama Y, Noguchi A, Takada M, Kaneko Y, Ishikawa T
- Organizer
 16th World Congress on Basic and Clinical Pharmacology. Basic Clin.Pharmacol.Toxicol., 107(Suppl.1):p.564
- Place of Presentation
 Copenhagen Denmark
- Year and Date
 2010-07-20
- Data Source
 KAKENHI-PROJECT-20590085
[Presentation] 膵β細胞におけるインスリン分泌調節への伸展活性化チャネルの関与2010
- Author(s)
  石川智久
- Organizer
  第87回日本生理学会大会
- Place of Presentation
  盛岡
- Year and Date
  2010-05-19
- Data Source
  KAKENHI-PROJECT-20590085
[Presentation] 膵β細胞株INS-1における低濃度NOのアポトーシス抑制作用2009
- Author(s)
  石川智久
- Organizer
  第9回日本NO学会学術集会
- Place of Presentation
  静岡
- Year and Date
  2009-05-08
- Data Source
  KAKENHI-PROJECT-20590085
[Presentation] A role of Ca^<2+> in hydrogen peroxide-induced apoptosis of pancreatic β-cells.2009
- Author(s)
 野口亜希子, 高田正弘, 石川智久
- Organizer
 第82回日本薬理学会年会J.Pharmacol.Sci.109(Supl.I), 100P
- Place of Presentation
 横浜
- Year and Date
 2009-03-18
- Data Source
 KAKENHI-PROJECT-20590085
[Presentation] 膵β細胞株INS-1における低濃度NOのアポトーシス抑制作用2009
- Author(s)
  石川智久、野口亜希子、高田正弘
- Organizer
  第9回日本NO学会学術集会、抄録集、p.104
- Place of Presentation
  静岡
- Year and Date
  2009-05-08
- Data Source
  KAKENHI-PROJECT-20590085
[Presentation] Interactive role of protein kinase kinase Cα and protein phosphatase 2A in the stretch-induced triphosphorylation of myosin light chain in canine cerebral artery2008
- Author(s)
  Kazuo Obara, Koichi Nakayama, Tomohisa Ishikawa
- Organizer
  第81回日本薬理学会年会
- Place of Presentation
  (横浜)J.Pharmacol.Sci.,106(Supl.I):118P,2008
- Year and Date
  2008-03-19
- Data Source
  KAKENHI-PROJECT-18590064
[Presentation] Interactive role of protein kinase Ca and protein phosphatase 2A in the stretch-induced triphosphorylation of myosin light chain in canine cerebral artery2008
- Author(s)
  Kazuo, Obara, Koichi, Nakayama, Tomohisa, Ishikawa
- Organizer
  The 81st Annual Meeting of The Japanese Pharmacological Society
- Place of Presentation
  Yokohama, Japan
- Description
  「研究成果報告書概要(欧文)」より
- Data Source
  KAKENHI-PROJECT-18590064
[Presentation] Interactive role of protein kinase Ca and protein phosphatase 2A in the stretch-induced triphosphorylation of myosin light chain in canine cerebral artery2008
- Author(s)
  Kazuo Obara, Koichi Nakavama, Tomohisa Ishikawa
- Organizer
  第81回日本薬理学会年会
- Place of Presentation
  (横浜)J.Pharmacol.Sci. (106(Supl.I):118P、2008)
- Year and Date
  2008-03-19
- Description
  「研究成果報告書概要(和文)」より
- Data Source
  KAKENHI-PROJECT-18590064
[Presentation] Role of protein kinase C isoforms in pressure-induced myogenic constriction in rat posterior cerebral arteries2008
- Author(s)
  Toshihide Kashihara, Koichi Nakavama, Tomohisa Ishikawa
- Organizer
  第81回日本薬理学会年会
- Place of Presentation
  (横浜)J:Pharmacol.Sci.,106(Supl.1):118P,2008
- Year and Date
  2008-03-19
- Data Source
  KAKENHI-PROJECT-18590064
[Presentation] Involvements of Rho-kinase and protein kinase C in stretch-induced triphosphorylation of myosin light chain in canine basilar artery2007
- Author(s)
  Kazuo Obara, Yoshihiko Ito, Hiroki Shimada, Koichi Nakayama, Tomohisa Ishikawa
- Organizer
  第80回日本薬理学会毎会
- Place of Presentation
  (名古屋)J.Pharmacol.Sci. (103(Supl.I):104P、2007)
- Year and Date
  2007-03-14
- Description
  「研究成果報告書概要(和文)」より
- Data Source
  KAKENHI-PROJECT-18590064
[Presentation] Roles of protein kinase C isoforms and Rho-kinase in long-term pressure-induced myogenic constriction in rat posterior cerebral arteries2007
- Author(s)
  Toshihide Kashihara, Koichi Nakavama, Tomohisa Ishikawa
- Organizer
  第5回国際受容体シンポジウム
- Place of Presentation
  (静岡)要旨集(p.103、2007)
- Description
  「研究成果報告書概要(和文)」より
- Data Source
  KAKENHI-PROJECT-18590064
[Presentation] Roles of protein kinase C isoforms and Rho-kinase in long-term pressure-induced myogenic constriction in rat posterior cerebral arteries2007
- Author(s)
  Toshihide Kashihara, Koichi Nakayama, Tomohisa Ishikawa
- Organizer
  第5回国際受容体シンポジウム
- Place of Presentation
  (静岡)要旨集、p.103,2007
- Data Source
  KAKENHI-PROJECT-18590064
[Presentation] Temporal changes in the contribution of protein kinase C isoforms to myogenic constriction in rat posterior cerebral arteries2007
- Author(s)
  Kashihara, T, Nakayama, K, Ishikawa, T
- Organizer
  American Heart Association Scientific Session 2007
- Place of Presentation
  Florida, U.S.A.
- Description
  「研究成果報告書概要(欧文)」より
- Data Source
  KAKENHI-PROJECT-17590224
[Presentation] Roles of protein kinase C isoforms and Rho-kinase in long-term pressure-induced myogenic constriction in rat posterior cerebral arteries2007
- Author(s)
  Kashihara, T, Nakayama, K, Ishikawa, T
- Organizer
  5th International Symposium on Receptor Mechanisms, Signal Transduction and Drug Effects
- Place of Presentation
  Shizuoka, Japan
- Description
  「研究成果報告書概要(欧文)」より
- Data Source
  KAKENHI-PROJECT-17590224
[Presentation] 1.新たな創薬ターゲットとしての膵β細胞機能調節因子シンポジウム1-「メタボリックシンドロームを巡る創薬」2007
- Author(s)
  石川智久、金子雪子、中山貢一
- Organizer
  生体機能と創薬シンポジウム2007
- Place of Presentation
  (金沢)講演要旨集(p.31-35、2007)
- Description
  「研究成果報告書概要(和文)」より
- Data Source
  KAKENHI-PROJECT-18590064
[Presentation] Involvements of Rho-kinase and protein kinase C in stretch-induced triphosphorylation of myosin light chain in canine basilar artery2007
- Author(s)
  Kazuo, Obara, Yoshihiko, Ito, Hiroki, Shimada, Koichi, Nakayama, Tomohisa, Ishikawa
- Organizer
  The 80th Annual Meeting of The Japanese Pharmacological Society
- Place of Presentation
  Nagoya, Japan
- Year and Date
  2007-03-15
- Description
  「研究成果報告書概要(欧文)」より
- Data Source
  KAKENHI-PROJECT-18590064
[Presentation] Regulatory molecule of pancreatic beta cell function as a novel target of development of drug. Symposium 1 [Development of new drugs toward metabolic syndrome]2007
- Author(s)
  Tomohisa, Ishikawa, Yukiko, Kaneko, Koichi, Nakayama
- Organizer
  Symposium of biofunction and development of new drugs, 2007
- Place of Presentation
  Kanazawa, Japan(symposium proceedings)
- Description
  「研究成果報告書概要(欧文)」より
- Data Source
  KAKENHI-PROJECT-18590064
[Presentation] Mechanism for local cooling-induced reduction of skin blood flow in mice2007
- Author(s)
  Mika, Suzuki, Masaki, Honda, Koichi, Nakayama, Tomohisa, Ishikawa
- Organizer
  5th International Symposium of Pharmacological Receptors
- Place of Presentation
  Shizuoka, Japan
- Description
  「研究成果報告書概要(欧文)」より
- Data Source
  KAKENHI-PROJECT-18590064
[Presentation] Role of protein kinase C isoforms in pressure-induced myogenic constriction in rat posterior middle cerebral arteries2007
- Author(s)
  Toshihide, Kashihara, Koichi, Nakayama, Tomohisa, Ishikawa
- Organizer
  The 80th Annual Meeting of The Japanese Pharmacological Society
- Place of Presentation
  Nagoya, Japan
- Year and Date
  2007-03-14
- Description
  「研究成果報告書概要(欧文)」より
- Data Source
  KAKENHI-PROJECT-18590064
[Presentation] Mechanism for local cooling-induced reduction of skin blood flow in mice2007
- Author(s)
  Mika Suzuki, Masaki Honda, Koichi Nakavama, Tomohisa Ishikawa
- Organizer
  第5回国際受容体シンポジウム
- Place of Presentation
  (静岡)要旨集(p.104,2007)
- Description
  「研究成果報告書概要(和文)」より
- Data Source
  KAKENHI-PROJECT-18590064
[Presentation] Temporal changes in the contribution of protein kinase C isoforms to myogenic constriction in rat posterior cerebral arteries2007
- Author(s)
  Toshihide Kashihara, Koichi Nakavama, Tomohisa Ishikawa
- Organizer
  American Heart Association Scientific Session 2007
- Place of Presentation
  (Florida,U.S.A.),Circulation(116,II-183-II-184,2007)
- Description
  「研究成果報告書概要(和文)」より
- Data Source
  KAKENHI-PROJECT-18590064
[Presentation] 1.新たな創薬ターゲットとしての膵β細胞機能調節因子シンポジウム1 「メタボリックシンドロームを巡る創薬」2007
- Author(s)
  石川智久、金子雪子、中山貢一
- Organizer
  生体機能と創薬しんポジウ2007
- Place of Presentation
  (金沢)、講演要旨集p.31-35、2007
- Data Source
  KAKENHI-PROJECT-18590064
[Presentation] 新たな創薬ターゲットとしての膵β細胞機能調節因子2007
- Author(s)
  石川智久
- Organizer
  生体機能と創薬シンポジウム2007
- Place of Presentation
  金沢市
- Year and Date
  2007-09-13
- Description
  「研究成果報告書概要(和文)」より
- Data Source
  KAKENHI-PROJECT-17590224
[Presentation] Roles of protein kinase C isoforms and Rho-kinase in long-term pressure-induced myogenic constriction in rat posterior middle cerebral arteries2007
- Author(s)
  Toshihide, Kashihara, Koichi, Nakayama, Tomohisa, Ishikawa
- Organizer
  5th International Symposium of Pharmacological Receptors
- Place of Presentation
  Shizuoka, Japan
- Description
  「研究成果報告書概要(欧文)」より
- Data Source
  KAKENHI-PROJECT-18590064
[Presentation] Temporal changes in the contribution of protein kinase C isoforms to myogenic constriction in rat posterior middle cerebral arteries2007
- Author(s)
  Toshihide, Kashihara, Koichi, Nakayama, Tomohisa, Ishikawa
- Organizer
  American Heart Association Scientific Session 2007
- Place of Presentation
  Orland, Florida, U.S.A
- Description
  「研究成果報告書概要(欧文)」より
- Data Source
  KAKENHI-PROJECT-18590064
[Presentation] Mechanism for local cooling-induced reduction of skin blood flow in mice2007
- Author(s)
  Suzuki, M, Honda, M, Nakayama, K, Ishikawa, T
- Organizer
  5th International Symposium on Receptor Mechanisms, Signal Transduction and Drug Effects
- Place of Presentation
  Shizuoka, Japan
- Description
  「研究成果報告書概要(欧文)」より
- Data Source
  KAKENHI-PROJECT-17590224
[Presentation] Role of protein kinase C isoforms in pressure-induced myogenic constriction in rat posterior cerebral arteries2007
- Author(s)
  Toshihide Kashihara, Koichi Nakayama, Tomohisa Ishikawa
- Organizer
  第80回日本薬理学会年会
- Place of Presentation
  (名古屋)J.Pharmacol.Sci. (103(Supl.I):152P、2007)
- Year and Date
  2007-03-14
- Description
  「研究成果報告書概要(和文)」より
- Data Source
  KAKENHI-PROJECT-18590064
[Presentation] Temporal changes in the contribution of protein kinase C isoforms to myogenic constriction in rat posterior cerebral arteries2007
- Author(s)
  Toshihide Kashihara, Koichi Nakayama, Tomohisa Ishikawa
- Organizer
  American Heart Association Scientific Session 2007
- Place of Presentation
  (Florida, U.S.A.), Circulation 116, II-183-II-184
- Data Source
  KAKENHI-PROJECT-18590064
[Presentation] Mechanism for local cooling-induced reduction of skin blood flow in mice2007
- Author(s)
  Mika Suzuki, Masaki Honda, Koichi Nakayama, Tomohisa Ishikawa
- Organizer
  第5回国際受容体シンポジウム
- Place of Presentation
  (静岡)要旨集、p.104,2007
- Data Source
  KAKENHI-PROJECT-18590064
[Presentation] Physiological role of nitric oxide in pancreatic β-cells2007
- Author(s)
  Tomohisa Ishikawa
- Organizer
  Pharmacology Seminar at the University of Vermont
- Place of Presentation
  Vermont,U.S.A.
- Year and Date
  2007-11-08
- Description
  「研究成果報告書概要(和文)」より
- Data Source
  KAKENHI-PROJECT-17590224
[Presentation] マウス局所性冷却誘発皮膚血流減少反応におけるα_<2c>アドレナリン受容体の関与2006
- Author(s)
 本多正樹、中山貢一、石川智久
- Organizer
 第16回日本循環薬理学会
- Place of Presentation
 (東京)講演要旨集(p32、2006)
- Year and Date
 2006-12-01
- Description
 「研究成果報告書概要(和文)」より
- Data Source
 KAKENHI-PROJECT-18590064
[Presentation] ラット後大脳動脈における圧誘発性血管収縮反応の細胞内情報伝達機構の時間的変化2006
- Author(s)
  柏原俊英、中山貢一、石川智久
- Organizer
  第16回日本循環薬理学会
- Place of Presentation
  (東京)講演要旨集(p32、2006)
- Year and Date
  2006-12-01
- Description
  「研究成果報告書概要(和文)」より
- Data Source
  KAKENHI-PROJECT-18590064
[Presentation] Involvement of protein kinase C and Rho kinase in pressure-induced constriction of rat middle cerebral artery2006
- Author(s)
  Toshihide, Kashihara, Tomohisa, Ishikawa, Koichi, Nakayama
- Organizer
  The 52nd Regional Meeting of Pharmaceutical Society of Japan, Tokai District
- Place of Presentation
  Shizuoka, Japan
- Year and Date
  2006-07-01
- Description
  「研究成果報告書概要(欧文)」より
- Data Source
  KAKENHI-PROJECT-18590064
[Presentation] 骨格筋の伸展刺激によるAkt,p38MAPKの活性化を伴うGLUT4の膜移行と糖取り込みの増加2006
- Author(s)
  伊藤由彦、小原一雄、中山、石川智久
- Organizer
  第52回日本薬理学会東海支部総会、大会
- Place of Presentation
  (静岡)講演要旨集(p.32、2006)
- Year and Date
  2006-07-01
- Description
  「研究成果報告書概要(和文)」より
- Data Source
  KAKENHI-PROJECT-18590064
[Presentation] Temporal change in intracellular signaling of pressure-induced constriction in rat middle cerebral artery2006
- Author(s)
  Toshihide, Kashihara, Koichi, Nakayama, Tomohisa, Ishikawa
- Organizer
  The 16th Annual Meeting of Japanese Association of Cardiovascular Pharmacology
- Place of Presentation
  Tokyo, Japan
- Year and Date
  2006-12-01
- Description
  「研究成果報告書概要(欧文)」より
- Data Source
  KAKENHI-PROJECT-18590064
[Presentation] Glucose uptake increased by passive stretching in skeletal muscle2006
- Author(s)
  Yoshihiko, Ito, Kazuo, Obara, Koichi, Nakayama, Tomohisa, Ishikawa
- Organizer
  The 11th Health and Long Longevity Forum
- Place of Presentation
  Shizuoka
- Year and Date
  2006-10-20
- Description
  「研究成果報告書概要(欧文)」より
- Data Source
  KAKENHI-PROJECT-18590064
[Presentation] Involvement of ac adrenergic receptor in cooling-induced reduction of cutaneous blood flow of mice2006
- Author(s)
  Mika, Suzuki, Masaki, Honda, Koichi, Nakayama, Tomohisa, Ishikawa
- Organizer
  The 52nd Regional Meeting of Pharmaceutical Society of Japan, Tokai District
- Place of Presentation
  Shizuoka, Japan
- Year and Date
  2006-07-01
- Description
  「研究成果報告書概要(欧文)」より
- Data Source
  KAKENHI-PROJECT-18590064
[Presentation] マウス局所冷却誘発皮膚血流減少反応におけるα_<2c>アドレナリン受容体の関与2006
- Author(s)
 本多正樹、中山貢一、石川智久
- Organizer
 第114回日本薬理学会関東部会
- Place of Presentation
 (千葉)日本薬理学雑誌(129,13P,2007)
- Year and Date
 2006-06-10
- Description
 「研究成果報告書概要(和文)」より
- Data Source
 KAKENHI-PROJECT-18590064
[Presentation] マウス局所性冷却誘発皮膚血流減少反応におけるα_<2c>アドレナリン受容体の関与2006
- Author(s)
 本多正樹、中山貢一、石川智久
- Organizer
 第115回日本薬理学会関東部会
- Place of Presentation
 (群馬)講演要旨集(P43、2006)
- Year and Date
 2006-09-28
- Description
 「研究成果報告書概要(和文)」より
- Data Source
 KAKENHI-PROJECT-18590064
[Presentation] 骨格筋の受動的伸展刺激(ストレッチ)による糖取り込みの増加2006
- Author(s)
  伊藤由彦、小原一男、中山貢一、石川智久
- Organizer
  第11回静、岡健康、長寿学術フォーラム
- Place of Presentation
  静岡
- Year and Date
  2006-10-20
- Description
  「研究成果報告書概要(和文)」より
- Data Source
  KAKENHI-PROJECT-18590064
[Presentation] インスリン分泌調節に寄与する諸因子の解析-NOを中心に2006
- Author(s)
  石川智久
- Organizer
  第6回Islet Biology研究会
- Place of Presentation
  東京
- Year and Date
  2006-07-21
- Description
  「研究成果報告書概要(和文)」より
- Data Source
  KAKENHI-PROJECT-17590224
[Presentation] ラットを用いた局所性冷却誘発皮膚血流減少反応のin vivo解析:シナプス前P_<2X>受容体の関与2006
- Author(s)
 本多正樹、中山貢一、石川智久
- Organizer
 第52回日本薬学会東海支部総会、大会
- Place of Presentation
 (静岡)講演要旨集(p.39、2006)
- Year and Date
 2006-07-01
- Description
 「研究成果報告書概要(和文)」より
- Data Source
 KAKENHI-PROJECT-18590064
[Presentation] Passive stretching produces Akt- and MAPK-dependent augmentations of GLUT4 translocation and glucose uptake in skeletal muscles2006
- Author(s)
  Yoshihiko, Ito, Kazuo, Obara, Koichi, Nakayama, Tomohisa, Ishikawa
- Organizer
  The 52nd Regional Meeting of Pharmaceutical Society of Japan, Tokai District
- Place of Presentation
  Shizuoka, Japan
- Year and Date
  2006-07-01
- Description
  「研究成果報告書概要(欧文)」より
- Data Source
  KAKENHI-PROJECT-18590064
[Presentation] マウスにおける冷却誘発皮膚血流減少反応へのα_<2c>アドレナリン受容体の関与2006
- Author(s)
 鈴木美香、本多正樹、中山貢一、石川智久
- Organizer
 第52回日本薬学会東海支部総会、大会
- Place of Presentation
 (静岡)講演要旨集(p.33、2006)
- Year and Date
 2006-07-01
- Description
 「研究成果報告書概要(和文)」より
- Data Source
 KAKENHI-PROJECT-18590064
[Presentation] ラット後大脳動脈圧誘発性収縮におけるプロテインキナーゼCとRhoキナーゼの役割2006
- Author(s)
  柏原俊英、石川智久、中山貢一
- Organizer
  第52回日本薬学会東海支部総会、大会
- Place of Presentation
  (静岡)講演要旨集(p.34、2006)
- Year and Date
  2006-07-01
- Description
  「研究成果報告書概要(和文)」より
- Data Source
  KAKENHI-PROJECT-18590064
[Presentation] KATP channel-independent pathways involved in glucose-induced insulin secretion. Symposium [Strategies for treatment of life style-related diseases]2006
- Author(s)
  Tomohisa, Ishikawa, Koichi, Nakayama
- Organizer
  The 79th Annual Meeting of The Japanese Pharmacological Society
- Place of Presentation
  Yokohama, Japan
- Year and Date
  2006-03-10
- Description
  「研究成果報告書概要(欧文)」より
- Data Source
  KAKENHI-PROJECT-18590064
[Presentation] Involvement of stretch-activated cation channel in the insulin secretion induced by inflation of pancreatic beta cells2006
- Author(s)
  Takaaki, Sunouchi, Koichi, Nakayama, Tomohisa, Ishikawa
- Organizer
  The 52nd Regional Meeting of Pharmaceutical Society of Japan, Tokai District
- Place of Presentation
  Shizuoka, Japan
- Year and Date
  2006-07-01
- Description
  「研究成果報告書概要(欧文)」より
- Data Source
  KAKENHI-PROJECT-18590064
[Presentation] K_<ATP> channel-hldependent pathways involved in glucose-induced insulin secretion2006
- Author(s)
 Tomohisa Ishikawa
- Organizer
 第79回日本薬理学会年会
- Place of Presentation
 横浜市
- Year and Date
 2006-03-10
- Description
 「研究成果報告書概要(和文)」より
- Data Source
 KAKENHI-PROJECT-17590224
[Presentation] 膵β細胞の膨張により誘発されるインスリン分泌における伸展活性化カチオンチャネルの役割2006
- Author(s)
  須之内孝明、中山貢一、石川智久
- Organizer
  第52回日本薬学会東激部総会、大会
- Place of Presentation
  (静岡)講演要旨集(p.33、2006)
- Year and Date
  2006-07-01
- Description
  「研究成果報告書概要(和文)」より
- Data Source
  KAKENHI-PROJECT-18590064
[Presentation] Involvement of adrenergic receptor in the reduction of skin blood flow induced by local cooling in mice2006
- Author(s)
  Masaki, Honda, Koichi, Nakayama, Tomohisa, Ishikawa
- Organizer
  The 16th Annual Meeting of Japanese Association of Cardiovascular Pharmacology
- Place of Presentation
  Tokyo, Japan
- Year and Date
  2006-12-01
- Description
  「研究成果報告書概要(欧文)」より
- Data Source
  KAKENHI-PROJECT-18590064
[Presentation] Involvement of stretch-activated cation channel in the insulin secretion induced by inflation of pancreatic beta cells2006
- Author(s)
  Takaaki, Sunouchi, Koichi, Nakayama, Tomohisa, Ishikawa
- Organizer
  The 114th Regional Meeting of The Japanese Pharmacological Society
- Place of Presentation
  Chiba, Japan
- Year and Date
  2006-06-10
- Description
  「研究成果報告書概要(欧文)」より
- Data Source
  KAKENHI-PROJECT-18590064
[Presentation] Passive stretching produces Akt- and MAPK-dependent augmentations of GLUT4 translocation and glucose uptake in skeletal muscles of mice : A novel pharmacological strategy for controlling glucose metabolism2006
- Author(s)
  Yoshihiko, Ito, Kazuo, Obara, Rikuko, Ikeda, Megumi, Ishii, Yoshiyuki, Tanabe, Tomohisa, Ishikawa, Koichi, Nakayama
- Organizer
  The 79th Annual Meeting of The Japanese Pharmacological Society
- Place of Presentation
  Yokohama, Japan
- Year and Date
  2006-03-10
- Description
  「研究成果報告書概要(欧文)」より
- Data Source
  KAKENHI-PROJECT-18590064
[Presentation] Multiple phosphorylation of myosin light chain induced by hemodynamic stimulus and intracellular signaling2006
- Author(s)
  Koichi, Nakayama, Tomohisa, Ishikawa, Kazuo, Obara, Yoshiyuki, Tanabe, Shigeru, Nishizawa, Masakuni, Degawa
- Organizer
  2005US Forum, University of Shizuoka
- Place of Presentation
  Shizuoka Japan
- Year and Date
  2006-03-02
- Description
  「研究成果報告書概要(欧文)」より
- Data Source
  KAKENHI-PROJECT-18590064
[Presentation] In vivo analysis of reduction of skin blood flow induced by local-cooling in rat : Role of presynaptic P2X receptor2006
- Author(s)
  Masaki, Honda, Koichi, Nakayama, Tomohisa, Ishikawa
- Organizer
  The 52th Regional Meeting of Pharmaceutical Society of Japan, Tokai District
- Place of Presentation
  Shizuoka, Japan
- Year and Date
  2006-07-01
- Description
  「研究成果報告書概要(欧文)」より
- Data Source
  KAKENHI-PROJECT-18590064
[Presentation] 膵β細胞の膨張により誘発されるインスリン分泌への伸展活性化カチオンチャネルの関与2006
- Author(s)
  須之内孝明、中山貢一、石川智久
- Organizer
  第114回薬理学会関東部会
- Place of Presentation
  (千葉)講演要旨集(p.34、2006)
- Year and Date
  2006-06-10
- Description
  「研究成果報告書概要(和文)」より
- Data Source
  KAKENHI-PROJECT-18590064
[Presentation] ジアジルグリセロールキナーゼの心機能調節における役割
- Author(s)
  植木桂一郎、齊藤真也、石川智久
- Organizer
  第23回日本循環薬理学会
- Place of Presentation
  福岡
- Data Source
  KAKENHI-PROJECT-23590192
[Presentation] 平滑筋を用いたアシル化ブテノリド誘導体の生物活性機序の解明
- Author(s)
  増田真也、伊藤誓悟、金井　慧、齊藤真也、石川智久
- Organizer
  次世代を担う創薬・医療薬理シンポジウム2013
- Place of Presentation
  熊本
- Data Source
  KAKENHI-PROJECT-23590192
[Presentation] 細胞膨張による膵β細胞インスリン分泌反応に関わるTRPチャネルの解析
- Author(s)
  金子雪子、高橋健吾、小川　藍、道津　功、石川智久
- Organizer
  第59回日本薬学会東海支部総会・大会
- Place of Presentation
  名古屋
- Data Source
  KAKENHI-PROJECT-23590192
[Presentation] ラット尾動脈および総腸骨動脈における興奮機構の相違
- Author(s)
  石田裕丈、菱沼瑛太、北川智章、齊藤真也、石川智久
- Organizer
  第128回日本薬理学会関東部会
- Place of Presentation
  東京
- Data Source
  KAKENHI-PROJECT-23590192
[Presentation] マウスin vivo実験による局所冷却誘発皮膚血流減少反応へのエストロゲンの影響の検討
- Author(s)
  岩崎　希、芹沢いづみ、石川智久
- Organizer
  第18回静岡　健康・長寿学術フォーラム
- Place of Presentation
  静岡
- Data Source
  KAKENHI-PROJECT-23590192
[Presentation] 肝星細胞の活性化に対する炎症メディエーターとカフェインの相互作用
- Author(s)
  鈴木彩加、山口桃生、齊藤真也、石川智久
- Organizer
  第18回静岡　健康・長寿学術フォーラム
- Place of Presentation
  静岡
- Data Source
  KAKENHI-PROJECT-23590192
[Presentation] α1アドレナリン受容体を介した冷却による皮膚血管収縮応答性増強メカニズムの解析
- Author(s)
  石田裕丈、菱沼瑛太、北川智章、齊藤真也、石川智久
- Organizer
  第23回日本循環薬理学会
- Place of Presentation
  福岡
- Data Source
  KAKENHI-PROJECT-23590192
[Presentation] α1アドレナリン受容体を介した冷却による皮膚血管収縮応答性増強メカニズムの解析
- Author(s)
  石田裕丈、菱沼瑛太、北川智章、齊藤真也、石川智久
- Organizer
  第59回日本薬学会東海支部総会・大会
- Place of Presentation
  名古屋
- Data Source
  KAKENHI-PROJECT-23590192
[Presentation] 膵β細胞ジアジルグリセロールキナーゼδの発現および機能解析と２型糖尿病への関与の検討
- Author(s)
  千葉里菜、金子雪子、佐藤太治、石渡千裕、藤貫貴大、石川智久
- Organizer
  日本病院薬剤師会東海ブロック・日本薬学会東海支部合同学術大会2013
- Place of Presentation
  三重
- Data Source
  KAKENHI-PROJECT-23590192

1. KANEKO Yukiko (00381038)

# of Collaborated Projects: 8 results

# of Collaborated Products: 167 results
2. 山口桃生 (30804819)

# of Collaborated Projects: 4 results

# of Collaborated Products: 59 results
3. GOTO Katsutoshi (30012660)

# of Collaborated Projects: 2 results

# of Collaborated Products: 0 results
4. KASUYA Yoshitoshi (70221877)

# of Collaborated Projects: 2 results

# of Collaborated Products: 0 results
5. SAKURAI Takeshi (60251055)

# of Collaborated Projects: 2 results

# of Collaborated Products: 0 results
6. TANABE Yoshiyuki (10275109)

# of Collaborated Projects: 2 results

# of Collaborated Products: 0 results
7. OBARA Kazuo (60117611)

# of Collaborated Projects: 2 results

# of Collaborated Products: 0 results
8. NAKAYAMA Koichi (50112769)

# of Collaborated Projects: 2 results

# of Collaborated Products: 53 results
9. YAMAGUCHI Iwao (30111389)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
10. MIYAUCHI Takashi (60222329)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
11. 濱裕 (30261796)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
12. 白井康仁 (60263399)

# of Collaborated Projects: 1 results

# of Collaborated Products: 1 results
13. 河田則文 (30271191)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
14. 濱島義隆 (40333900)

# of Collaborated Projects: 1 results

# of Collaborated Products: 3 results
15. 原幸大 (80729343)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
16. ASANO Toshio

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
17. 浅野俊雄

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
18. KANAZAWA Takanori

# of Collaborated Projects: 0 results

# of Collaborated Products: 1 results
19. AKIRA Minami

# of Collaborated Projects: 0 results

# of Collaborated Products: 1 results
20. KIMURA Toshihide

# of Collaborated Projects: 0 results

# of Collaborated Products: 1 results
21. TERABAYASHI Takeshi

# of Collaborated Projects: 0 results

# of Collaborated Products: 1 results
22. 近藤啓

# of Collaborated Projects: 0 results

# of Collaborated Products: 1 results
23. 石崎敏理

# of Collaborated Projects: 0 results

# of Collaborated Products: 1 results

Ishikawa Tomohisa 石川 智久

ISHIKAWA Tomohisa 石川 智久

Research Projects

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Co-Researchers

ヒト呼気中揮発性有機物の構成解析に基づく肝線維化簡易診断法の確立に向けた基盤研究Principal Investigator

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肝星細胞における液－液相分離を標的としたNASH進行スイッチ制御の確立Principal Investigator

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Development of non-invasive assessment method for NASH using expired gas analysis with AI-powered gas chromatographyPrincipal Investigator

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Basic study for developing NASH therapeutic drugs by using a small molecule derived from the cellular slime mold serving as a lead compoundPrincipal Investigator

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Development of disease model in mice on the basis of mechanisms for pathogenesis of gestational diabetes.Principal Investigator

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Intracellular lipid signaling analysis for the development of novel diabetes therapeutic agents targeting neogenesis and proliferation of pancreatic beta-cellsPrincipal Investigator

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Possible involvement of gut-derived melatonin as a negative regulator of insulin secretionPrincipal Investigator

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Role of crosstalk between peripheral circadian clock and NO-cGMP system of pancreatic beta-cells in the pathogenesis of diabetesPrincipal Investigator

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Intermolecular network involved in calcium-dependent apoptosis of pancreatic beta-cells and possible targets for diabetes treatmentPrincipal Investigator

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Roles of TRP channels in response to exposure with high concentrations of glucose in pancreatic β cellsPrincipal Investigator

Ishikawa Tomohisa 石川智久

ISHIKAWA Tomohisa 石川智久