KAMATA Hideaki 鎌田英明

Researcher Number	10233925
Other IDs
External Links
Affiliation (based on the past Project Information) *help	2019: 広島大学, 医系科学研究科(医), 准教授 2018: 広島大学, 医歯薬保健学研究院, 准教授 2015 – 2016: 広島大学, 医歯薬保健学研究院(医), 准教授 2012 – 2014: 広島大学, 医歯薬保健学研究院, 准教授 2013: 広島大学, 大学院医歯薬保健学研究院, 准教授 … More 2012: 広島大学, 医歯薬保健学研究院(医), 准教授 2012: 広島大学, 医歯薬学総合研究科, 准教授 2008 – 2011: Hiroshima University, 大学院・医歯薬学総合研究科, 准教授 2007: Hiroshima University, Graduate School of Biomedical Sciences, Associate Professor 2006: 広島大学, 大学院医歯(薬)学総合研究科, 助教授 2005: 兵庫県立大学, 大学院・生命理学研究科, 助手 2005: University of Hyogo, Life Science, Assistant Professor, 大学院生命理学研究科, 助手 2004: 兵庫県立大学, 大学院・理学研究科, 助手 1992 – 2000: 姫路工業大学, 理学部, 助手 Less
Review Section/Research Field	Principal Investigator Functional biochemistry / Biological Sciences / Neurochemistry/Neuropharmacology / Biological Sciences / Basic Section 50010:Tumor biology-related / Cell biology Except Principal Investigator Functional biochemistry / Tumor biology / 広領域 / 血管生物学 / Metabolomics / Biological Sciences / Cell biology
Keywords	Principal Investigator 炎症 / NF-kB / NF-κB / 酸化ストレス / IKKb / IKKβ / 腫瘍壊死因子 / 活性酸素種 / レドックス / シグナル伝達 … More / 発がん / ROS / JNK / ユビキチン / レドックス制御 / N-アセチルシステイン / アポトーシス / 癌 / 遺伝子 / 細胞・組織 / 生体分子 / MAPキナーゼホスファター / がん / ネクローシス / 肝臓 / TNF / 活性酸素 / ホスファターゼ / EGFレセプター / キナーゼ / AP-1 / NFkB / MAPキナーゼ / 細胞内情報伝達 / 遺伝子発現 / Cyp遺伝子 / HNF4 / 胆汁酸 / 肝細胞がん / 化学発がん / HNF4a / RIPK3 / Rab11b / Rab11B / 細胞内小胞輸送 / ネクロプトーシス / MAP KINASE PHOSPHATASE / OXIDATIVE STRES / INFLAMMATION / CANCER / REDOX / MAPキナーゼホスファターゼ / Phosphatase / Oxidative stress / Inflammation / Cancer / Redox / MKP / IKKBβ / HIF1-α / クエン酸 / 代謝 / 翻訳 / 酸素 / HIF-1a / クエン酸回路 / HIF1 / タンパク質分解 / 発癌 / 肝硬変 / 線維化 / 核 / 細胞質 / IKK / ユビキチン化 / 核移行 / プロテアソーム細胞死 / UV / ストレス応答 / 細胞情報伝達機構 / プロテアソーム / 細胞死 / NF-KB / CK2 / p38 / 紫外線 / KF-κB / カスパーゼ / RIP-1 / Itch / IkBキナーゼ / β / IKKα / Sos / Shc / TrkA / PC12 / プロテインキナーゼ / 細胞増殖 / 分化 / レセプターチロシンキナーゼ / EGF / NGF / N-アセチルシスティン / Ras / 細胞分化 / 細胞内レドックス / 細胞内情報伝達系 / 神経成長因子 / ネガティブ選択 / ポジティブ / ヒトグリア細胞 / IL-8 / Hyg-TK遺伝子 / IL-1 … More Except Principal Investigator ホスホリパーゼC / PHドメイン / シグナル伝達 / 高血圧自然発症ラット(SHR) / 遺伝子発現 / 遺伝子連鎖解析 / 高血圧 / 肝細胞死 / 肝線維化 / IKK / HNF4 / DEN / HCC / IKKβ / シトクロムp450 / 化学発がん / 肝がん / 肝炎 / pleckstrin homology(PH) / phophoinositide / cytoskeleton / ameba movement / osmotic stress / nuclear import / nuclear export / phospholipase C / 緑色けい光タンパク(GFP) / 浸透圧 / 細胞内局在 / プレクストリン相同性領域(ph領域 / 脂質・タンパク相互作用 / トランスロケーション / 核外移行シグナル / 浸透圧ショック / プレクストリン相同性領域 / 細胞運動 / 緑色蛍光タンパク(GFP) / 核外移行シグナル(NES) / 核移行シグナル(NLS) / プレクストリンホモロジー(PH)ドメイン / イノシトールリン脂質 / 細胞骨格 / アメーバ運動 / 浸透圧ストレス / 核移行 / 核外移行 / homologous recombination / membrane protein / hyperthermophile / amino acid transporter / 融合タンパク質 / 大量発現 / 好熱菌 / 相同組み替え / 膜タンパク質 / 超好熱菌 / アミノ酸トランスポーター / PH domain / Linkage analysis / Gene expression / Spontaneously Hypertensive Rat / Phospholipase / Calcium ion / Vascular cells / Hypertension / 遺伝子クローニング / 血管内皮・平滑筋細胞 / 高血圧自然発症ラット / 連鎖解析 / ホスホリパーゼ / カルシウムイオン / 血管細胞 / 脂肪細胞分化 / 肥満 / 脂肪肝 / グルコーストランスポーター / 糖代謝 / 糖尿病 / 糖取り込み / プロテオミクス / 代謝 / インスリン / 生体分子 / 生理活性 / 酸化ストレス / ケミカルバイオロジー / 活性酸素 / IκBキナーゼ / NFκB / AP-1 / MAPギナーゼ / 活性酸素種 / Mox-1 / マイクロインジェクション / 膜ターゲティング / Ca^<2+>結合 / C2領域 / プレクストリンホモロジー領域 / IP_3結合 / 細胞内カルシウム / アミノ酸置換 Less

Molecular mechanisms of gene expression linked to chronic inflammation and hepatocellular carcinogenesisPrincipal Investigator
- Principal Investigator
  
  鎌田英明
- Project Period (FY)
  2019 – 2021
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Review Section
  
  Basic Section 50010:Tumor biology-related
- Research Institution
  Hiroshima University
Nuclear IKKbeta regulates DEN-induced hepatic carcinogenesis through the suppression of DNA-binding activity of HNF4alpha
- Principal Investigator
  
  TSUCHIYA Yoshihiro
- Project Period (FY)
  2016 – 2018
- Research Category
  
  Grant-in-Aid for Young Scientists (B)
- Research Field
  
  Tumor biology
- Research Institution
  Hiroshima Jogakuin University
  Hiroshima University
計画的細胞死に共役した細胞内小胞輸送の改変と細胞外シグナルの生成Principal Investigator
- Principal Investigator
  
  鎌田英明
- Project Period (FY)
  2015 – 2016
- Research Category
  
  Grant-in-Aid for Scientific Research on Innovative Areas (Research in a proposed research area)
- Review Section
  
  Biological Sciences
- Research Institution
  Hiroshima University
腫瘍壊死因子が産生する活性酸素によるシグナル制御と炎症と発がんPrincipal Investigator
- Principal Investigator
  
  鎌田英明
- Project Period (FY)
  2015 – 2016
- Research Category
  
  Grant-in-Aid for Scientific Research on Innovative Areas (Research in a proposed research area)
- Review Section
  
  Biological Sciences
- Research Institution
  Hiroshima University
Crosstalk between citrate sycle and gene expression system and inflammation and cancerPrincipal Investigator
- Principal Investigator
  
  KAMATA hideaki
- Project Period (FY)
  2012 – 2014
- Research Category
  
  Grant-in-Aid for Challenging Exploratory Research
- Research Field
  
  Functional biochemistry
- Research Institution
  Hiroshima University
Involvement of NF-kB regulation by nuclear IKKb in inflammation and cancerPrincipal Investigator
- Principal Investigator
  
  KAMATA Hideaki
- Project Period (FY)
  2011 – 2014
- Research Category
  
  Grant-in-Aid for Scientific Research (B)
- Research Field
  
  Functional biochemistry
- Research Institution
  Hiroshima University
Involvement of cellular stress-medicated NF-kB activation in inflammation and cancerPrincipal Investigator
- Principal Investigator
  
  KAMATA Hideaki
- Project Period (FY)
  2009 – 2010
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Research Field
  
  Functional biochemistry
- Research Institution
  Hiroshima University
Signaling Functions of Reactive Oxygen Species
- Principal Investigator
  
  AKAIKE Takaaki
- Project Period (FY)
  2008 – 2013
- Research Category
  
  Grant-in-Aid for Scientific Research on Innovative Areas (Research in a proposed research area)
- Review Section
  
  Biological Sciences
- Research Institution
  Tohoku University
  Kumamoto University
Cellular signaling systems regulated by oxidative stress and ROS-sensitive phosphatasesPrincipal Investigator
- Principal Investigator
  
  KAMATA HIDEAKI (KAMATA Hideaki)
- Project Period (FY)
  2008 – 2012
- Research Category
  
  Grant-in-Aid for Scientific Research on Innovative Areas (Research in a proposed research area)
- Review Section
  
  Biological Sciences
- Research Institution
  Hiroshima University
Elucidation of the molecular mechanisms underlying insulin resistance and metabolic disorders using a proteomics technology
- Principal Investigator
  
  ASANO Tomoichiro
- Project Period (FY)
  2008 – 2010
- Research Category
  
  Grant-in-Aid for Scientific Research (B)
- Research Field
  
  Metabolomics
- Research Institution
  Hiroshima University
腫瘍壊死因子によるユビキチンリガーゼItchを介したタンパク質分解と細胞応答Principal Investigator
- Principal Investigator
  
  鎌田英明
- Project Period (FY)
  2007 – 2008
- Research Category
  
  Grant-in-Aid for Scientific Research on Priority Areas
- Review Section
  
  Biological Sciences
- Research Institution
  Hiroshima University
Redox regulation of inflammation and carcinogenesis mediated by NF-κB/IKKβ and dual-specificity phosphatasePrincipal Investigator
- Principal Investigator
  
  KAMATA Hideaki
- Project Period (FY)
  2006 – 2007
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Research Field
  
  Functional biochemistry
- Research Institution
  Hiroshima University
Regulation of bioenergy by NF-kB/IKKb signaling and oxidative stress-related diseasesPrincipal Investigator
- Principal Investigator
  
  KAMATA Hideaki
- Project Period (FY)
  2004 – 2005
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Research Field
  
  Functional biochemistry
- Research Institution
  University of Hyogo
細胞のガン化に連関した細胞内シグナル伝達系のレドックス制御機構Principal Investigator
- Principal Investigator
  
  鎌田英明
- Project Period (FY)
  2000
- Research Category
  
  Grant-in-Aid for Scientific Research on Priority Areas (C)
- Review Section
  
  Biological Sciences
- Research Institution
  Himeji Institute of Technology
細胞増殖のレドックス制御-Mox1による活性酸素種産生と細胞のがん化機構の解析-
- Principal Investigator
  
  平田肇
- Project Period (FY)
  2000
- Research Category
  
  Grant-in-Aid for Exploratory Research
- Research Field
  
  Cell biology
- Research Institution
  Himeji Institute of Technology
細胞内シグナル伝達系におけるレドックス制御機構の解析Principal Investigator
- Principal Investigator
  
  鎌田英明
- Project Period (FY)
  1999 – 2000
- Research Category
  
  Grant-in-Aid for Encouragement of Young Scientists (A)
- Research Field
  
  Cell biology
- Research Institution
  Himeji Institute of Technology
REGULATION AND INTRACELLULAR LOCALISATION OF PHOSPHOIN OSITIDE-BINDING PROTEINS.
- Principal Investigator
  
  YAGISAWA Hitoshi
- Project Period (FY)
  1998 – 2001
- Research Category
  
  Grant-in-Aid for Scientific Research (B).
- Research Field
  
  広領域
- Research Institution
  Himeji Institute of Technology
細胞の生存・分化・増殖シグナルにおけるレドックス制御機構の解析Principal Investigator
- Principal Investigator
  
  鎌田英明
- Project Period (FY)
  1997 – 1998
- Research Category
  
  Grant-in-Aid for Encouragement of Young Scientists (A)
- Research Field
  
  Neurochemistry/Neuropharmacology
- Research Institution
  Himeji Institute of Technology
δ型ホスホリパーゼCの構造と細胞内ターゲッティング
- Principal Investigator
  
  八木澤仁
- Project Period (FY)
  1996
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Research Field
  
  Functional biochemistry
- Research Institution
  Himeji Institute of Technology
神経成長因子(NGF)の細胞内情報伝達系と細胞内レドックス制御の関連Principal Investigator
- Principal Investigator
  
  鎌田英明
- Project Period (FY)
  1996
- Research Category
  
  Grant-in-Aid for Encouragement of Young Scientists (A)
- Research Field
  
  Neurochemistry/Neuropharmacology
- Research Institution
  Himeji Institute of Technology
Structure and Function Relatioship of Amino Acid Transporter from Hyperthermophilic Bacterium.
- Principal Investigator
  
  HIRATA Hajime
- Project Period (FY)
  1995 – 1996
- Research Category
  
  Grant-in-Aid for Scientific Research (B)
- Research Field
  
  Functional biochemistry
- Research Institution
  HIMEJI INSTITUTE OF TECHNOLOGY
神経系細胞におけるサイトカインの細胞内情報伝達システムの解明Principal Investigator
- Principal Investigator
  
  鎌田英明
- Project Period (FY)
  1993
- Research Category
  
  Grant-in-Aid for Encouragement of Young Scientists (A)
- Research Field
  
  Neurochemistry/Neuropharmacology
- Research Institution
  Himeji Institute of Technology
Blood Pressure Control by Intracellular Ca2_+-Modulatory Factors in Vascular Endothelial and Smooth Muscle Cells
- Principal Investigator
  
  YAGISAWA Hitoshi
- Project Period (FY)
  1993 – 1994
- Research Category
  
  Grant-in-Aid for General Scientific Research (C)
- Research Field
  
  血管生物学
- Research Institution
  Himeji Institute of Technology(HIT)
高血圧自然発症ラット(SHR)における高血圧発症機構の分子生物学解析
- Principal Investigator
  
  YAGISAWA Hitoshi
- Project Period (FY)
  1992
- Research Category
  
  Grant-in-Aid for Scientific Research on Priority Areas
- Research Institution
  Himeji Institute of Technology

[Journal Article] Structural instability of IκB kinase β promotes autophagic degradation through enhancement of Keap1 binding2018
- Author(s)
  Kanamoto Mayu、Tsuchiya Yoshihiro、Nakao Yuki、Suzuki Takafumi、Motohashi Hozumi、Yamamoto Masayuki、Kamata Hideaki
- Journal Title
  
  PLOS ONE
  
  Volume: 13 Issue: 11 Pages: e0203978-e0203978
- DOI
  10.1371/journal.pone.0203978
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-18K19417, KAKENHI-PROJECT-17KK0183, KAKENHI-PUBLICLY-18H04794, KAKENHI-PUBLICLY-18H04963, KAKENHI-PROJECT-18H02621, KAKENHI-PROJECT-17F17116, KAKENHI-PROJECT-17K19508, KAKENHI-PROJECT-16K18419, KAKENHI-PROJECT-17K15590
[Journal Article] Distinct B subunits of PP2A regulate the NF-κB signalling pathway through dephosphorylation of IKKβ, IκBα and RelA2017
- Author(s)
  Tsuchiya Yoshihiro、Osaki Keiko、Kanamoto Mayu、Nakao Yuki、Takahashi Ena、Higuchi Toru、Kamata Hideaki
- Journal Title
  
  FEBS Letters
  
  Volume: 591 Issue: 24 Pages: 4083-4094
- DOI
  10.1002/1873-3468.12912
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-16K18419
[Journal Article] USP15 attenuates IGF-I signaling by antagonizing Nedd4-induced IRS-2 ubiquitination.2017
- Author(s)
  Fukushima T, Yoshihara H, Furuta H, Hakuno F, Iemura SI, Natsume T, Nakatsu Y, Kamata H, Asano T, Komada M, Takahashi SI.
- Journal Title
  
  Biochemical and Biophysical Research Communications
  
  Volume: 484 Issue: 3 Pages: 522-528
- DOI
  10.1016/j.bbrc.2017.01.101
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PUBLICLY-15H01382, KAKENHI-PUBLICLY-15H01406, KAKENHI-PLANNED-24112003, KAKENHI-PLANNED-24115007, KAKENHI-PROJECT-15H04293, KAKENHI-PROJECT-26460369, KAKENHI-PROJECT-15H04583
[Journal Article] HECT‐Type Ubiquitin E3 Ligase ITCH Interacts With Thioredoxin‐Interacting Protein and Ameliorates Reactive Oxygen Species Induced Cardiotoxicity2016
- Author(s)
  Yoichiro Otaki, Hiroki Takahashi, Tetsu Watanabe, Akira Funayama, Shunsuke Netsu, Yuki Honda, Taro Narumi, Shinpei Kadowaki, Hiromasa Hasegawa, Shintaro Honda, Takanori Arimoto, Tetsuro Shishido, Takuya Miyamoto, Hideaki Kamata, Osamu Nakajima, Isao Kubota
- Journal Title
  
  Am Heart Assoc.
  
  Volume: 5 Issue: 1
- DOI
  10.1161/jaha.115.002485
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PUBLICLY-15H01382, KAKENHI-PUBLICLY-15H01406, KAKENHI-PROJECT-26893025, KAKENHI-PROJECT-26860541
[Journal Article] Involvement of resistin-like molecule β in the development of methionine-choline deficient diet-induced non-alcoholic steatohepatitis in mice.2016
- Author(s)
  Okubo H, Kushiyama A, Sakoda H, Nakatsu Y, Iizuka M, Taki N, Fujishiro M, Fukushima T, Kamata H, Nagamachi A, Inaba T, Nishimura F, Katagiri H, Asahara T, Yoshida Y, Chonan O, Encinas J, Asano T.
- Journal Title
  
  Sci Rep.
  
  Volume: 6 Issue: 1 Pages: 20157-20157
- DOI
  10.1038/srep20157
- NAID
  120006796541
- Peer Reviewed / Open Access / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-26460369, KAKENHI-PROJECT-25253067, KAKENHI-PROJECT-25461372, KAKENHI-PROJECT-26670447, KAKENHI-PROJECT-26860735, KAKENHI-PUBLICLY-15H01382, KAKENHI-PUBLICLY-15H01406, KAKENHI-PROJECT-16H05555, KAKENHI-PROJECT-16K09791
[Journal Article] Mosapride citrate improves nonalcoholic steatohepatitis with increased fecal lactic acid bacteria and plasma glucagon-like peptide-1 level in a rodent model.2015
- Author(s)
  Hirofumi Okubo, Yusuke Nakatsu, Hideyuki Sakoda, Akifumi Kushiyama, Midori Fujishiro, Toshiaki Fukushima, Yasuka Matsunaga, Haruya Ohno, Masayasu Yoneda, Hideaki Kamata, Takanori Shinjo, Misaki Iwashita, Fusanori Nishimura, and Tomoichiro Asano
- Journal Title
  
  Am. J. Physiol. Gastrointest. Liver Physiol.
  
  Volume: 308 Issue: 2 Pages: 151-158
- DOI
  10.1152/ajpgi.00198.2014
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-23370062, KAKENHI-PROJECT-24591314, KAKENHI-PROJECT-24657092, KAKENHI-PROJECT-24790928, KAKENHI-PROJECT-25461372, KAKENHI-PROJECT-26460369, KAKENHI-PUBLICLY-15H01382, KAKENHI-PUBLICLY-15H01406
[Journal Article] The xanthine oxidase inhibitor febuxostat suppresses development of nonalcoholic steatohepatitis in a rodent model.2015
- Author(s)
  Nakatsu Y, Seno Y, Kushiyama A, Sakoda H, Fujishiro M, Katasako A, Mori K, Matsunaga Y, Fukushima T, Kanaoka R, Yamamotoya T, Kamata H, Asano T.
- Journal Title
  
  Am J Physiol Gastrointest Liver Physiol.
  
  Volume: 309(1) Issue: 1 Pages: G42-G51
- DOI
  10.1152/ajpgi.00443.2014
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-26460369, KAKENHI-PUBLICLY-15H01382, KAKENHI-PUBLICLY-15H01406, KAKENHI-PROJECT-25461372
[Journal Article] Pin1 Inhibitor Juglone Exerts Anti-Oncogenic Effects on LNCaP and DU145 Cells despite the Patterns of Gene Regulation by Pin1 Differing between These Cell Lines.2015
- Author(s)
  Kanaoka R, Kushiyama A, Seno Y, Nakatsu Y, Matsunaga Y, Fukushima T, Tsuchiya Y, Sakoda H, Fujishiro M, Yamamotoya T, Kamata H, Matsubara A, Asano T.
- Journal Title
  
  PLoS One.
  
  Volume: 10 (6) Issue: 6 Pages: e0127467-e0127467
- DOI
  10.1371/journal.pone.0127467
- Peer Reviewed / Acknowledgement Compliant / Open Access
- Data Source
  KAKENHI-PROJECT-15K10591, KAKENHI-PROJECT-26460369, KAKENHI-PUBLICLY-15H01382, KAKENHI-PUBLICLY-15H01406, KAKENHI-PROJECT-25461372
[Journal Article] Nedd4-induced mono-ubiquitination of IRS-2 enhances IGF signaling and mitogenic activity.2015
- Author(s)
  Toshiaki Fukushima, Hidehito Yoshihara, Haruka Furuta, Fumihiko Hakuno, Jing Luan, Cunming Duan, Yasushi Saeki, Keiji Tanaka, Shun-Ichiro Iemura, TohruNatsume, Kazuhiro Chida, Yusuke Nakatsu, Hideaki Kamata, Tomoichiro Asano, and Shin-Ichiro Takahashi
- Journal Title
  
  Nature communications
  
  Volume: 6 Issue: 1 Pages: 6780-6780
- DOI
  10.1038/ncomms7780
- NAID
  120006348510
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-23370062, KAKENHI-PROJECT-24380152, KAKENHI-PROJECT-24657092, KAKENHI-PROJECT-24790928, KAKENHI-PROJECT-25850220, KAKENHI-PROJECT-26460369, KAKENHI-PUBLICLY-15H01382, KAKENHI-PUBLICLY-15H01406, KAKENHI-PLANNED-24112008, KAKENHI-ORGANIZER-24115001, KAKENHI-PLANNED-24115007, KAKENHI-PROJECT-25221204, KAKENHI-PROJECT-15H04583, KAKENHI-PROJECT-26000014
[Journal Article] LUBAC Formation Is Impaired in the Livers of Mice with MCD-Dependent Nonalcoholic Steatohepatitis.2015
- Author(s)
  Matsunaga Y, Nakatsu Y, Fukushima T, Okubo H, Iwashita M, Sakoda H, Fujishiro M, Yamamotoya T, Kushiyama A, Takahashi S, Tsuchiya Y, Kamata H, Tokunaga F, Iwai K, Asano T.
- Journal Title
  
  Mediators Inflamm.
  
  Volume: 2015 Issue: 1 Pages: 125380-125380
- DOI
  10.1155/2015/125380
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-15K08259, KAKENHI-PROJECT-26460369, KAKENHI-PUBLICLY-15H01172, KAKENHI-PUBLICLY-15H01382, KAKENHI-PUBLICLY-15H01406, KAKENHI-PROJECT-15H04694, KAKENHI-PROJECT-25461372, KAKENHI-PROJECT-26670154, KAKENHI-PLANNED-24112002, KAKENHI-PROJECT-25221204, KAKENHI-PROJECT-25253019
[Journal Article] DPP-IV inhibitor anagliptin exerts anti-inflammatory effects on macrophages, adipocytes, and mouse livers by suppressing NF-κB activation.2015
- Author(s)
  Shinjo T, Nakatsu Y, Iwashita M, Sano T, Sakoda H, Ishihara H, Kushiyama A, Fujishiro M, Fukushima T, Tsuchiya Y, Kamata H, Nishimura F, Asano T.
- Journal Title
  
  Am J Physiol Endocrinol Metab.
  
  Volume: 309(3) Issue: 3 Pages: E214-E223
- DOI
  10.1152/ajpendo.00553.2014
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-26460369, KAKENHI-PROJECT-15K15351, KAKENHI-PUBLICLY-15H01382, KAKENHI-PUBLICLY-15H01406, KAKENHI-PROJECT-25461372
[Journal Article] Prolyl isomerase Pin1 negatively regulates AMP-activated protein kinase (AMPK) by associating with the CBS domain in the γ subunit2015
- Author(s)
  Nakatsu Y, Iwashita M, Sakoda H, Ono H, Nagata K, Matsunaga Y, Fukushima T, Fujishiro M, Kushiyama A, Kamata H, Takahashi S, Katagiri H, Honda H, Kiyonari H, Uchida T, Asano T
- Journal Title
  
  J Biol Chem
  
  Volume: 290 Issue: 40 Pages: 24255-24266
- DOI
  10.1074/jbc.m115.658559
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-15K09398, KAKENHI-PROJECT-26460369, KAKENHI-PROJECT-26660287, KAKENHI-PUBLICLY-15H01382, KAKENHI-PUBLICLY-15H01406, KAKENHI-PROJECT-25253067, KAKENHI-PROJECT-25461372, KAKENHI-PROJECT-26670447, KAKENHI-PROJECT-26252064, KAKENHI-PROJECT-16H05220
[Journal Article] TNF-αによるリン酸化シグナルと酸化ストレスのクロストークと細胞死2013
- Author(s)
  土谷佳弘, 鎌田英明
- Journal Title
  
  医学の歩み
  
  Volume: Vol.247 Pages: 806-810
- Data Source
  KAKENHI-PLANNED-20117012
[Journal Article] Promotion of DNA repair by nuclear IKKβ phosphorylation of ATM in response to genotoxic stimuli2013
- Author(s)
  Kei Sakamoto, Yohko Hikiba, Hayato Nakagawa, Yoshihiro Hirata, Yoku Hayakawa, Hiroto Kinoshita, Wachiko Nakata, Kosuke Sakitani, Ryota Takahashi, Masao Akanuma, Hideaki Kamata, Shin Maeda
- Journal Title
  
  Oncogene
  
  Volume: 32 Pages: 1854-1862
- Peer Reviewed
- Data Source
  KAKENHI-PLANNED-20117012
[Journal Article] Integrator complex plays an essential role in adipose differentiation2013
- Author(s)
  Yuichiro Otani, Yusuke Nakatsu, Hideyuki Sakoda, Toshiaki Fukushima, Midori Fujishiro, Akifumi Kushiyama, Hirofumi Okubo, Yoshihiro Tsuchiya, Haruya Ohno, Shin-Ichiro Takahashi, Fusanori Nishimura, Hideaki Kamata, Hideki Katagiri, Tomoichiro Asano
- Journal Title
  
  Biochemical Biophysical Research Communications
  
  Volume: 434 Pages: 197-202
- Peer Reviewed
- Data Source
  KAKENHI-PLANNED-20117012
[Journal Article] Valsartan restores inflammatory response by macrophages in adipose hepatic tissues of LPS-infused mice2013
- Author(s)
  Misaki Iwashita, Yusuke Nakatsu, Hideyuki Sakoda, Midori Fujishiro, Akifumi Kushiyama, Toshiaki Fukushima,Sonoko Kumamoto, Takanori Shinjo, Hideaki Kamata, Fusanori Nishimura Tomoichiro Asano
- Journal Title
  
  Adipocyte
  
  Volume: 2 Pages: 28-32
- Peer Reviewed
- Data Source
  KAKENHI-PLANNED-20117012
[Journal Article] Valsartan restores inflammatory response by macrophages in adipose and hepatic tissues of LPS-infused mice.2013
- Author(s)
  Iwashita M, Nakatsu Y, Sakoda H, Fujishiro M, Kushiyama A, Fukushima T, Kumamoto S, Shinjo T, Kamata H, Nishimura F, Asano T.
- Journal Title
  
  Adipocyte
  
  Volume: 2 Pages: 28-32
- Peer Reviewed
- Data Source
  KAKENHI-PLANNED-20117012
[Journal Article] Valsartan restores inflammatory response by macrophages in adipose and hepatic tissues of LPS-infused mice.2013
- Author(s)
  Iwashita M, Nakatsu Y, Sakoda H, Fujishiro M, Kushiyama A, Fukushima T, Kumamoto S, Shinjo T, Kamata H, Nishimura F, Asano T.
- Journal Title
  
  Adipocyte
  
  Volume: 2 Pages: 28-32
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-23370062
[Journal Article] Integrator complex plays anessential role inadipose differentiation2013
- Author(s)
  Otani Y, Nakatsu Y, Sakoda H, Fukushima T, Fujishiro M, Kushiyama A, Okubo H, Tsuchiya Y, Ohno H, Takahashi S, Nishimura F, Kamata H, Katagiri H, Asano T.
- Journal Title
  
  Biochemical and Biophysical Research Communications
  
  Volume: 434 Issue: 2 Pages: 197-202
- DOI
  10.1016/j.bbrc.2013.03.029
- Peer Reviewed
- Data Source
  KAKENHI-PLANNED-20117012, KAKENHI-PROJECT-23370062, KAKENHI-PROJECT-23791047, KAKENHI-PROJECT-24591314, KAKENHI-PROJECT-24591315, KAKENHI-PROJECT-24657092, KAKENHI-PROJECT-24790928
[Journal Article] Valsartan restores inflammatory response by macrophages in adipose and hepatic tissues of LPS-infused mice.2013
- Author(s)
  Misaki Iwashita, Yusuke Nakatsu, Hideyuki Sakoda, Midori Fujishiro, Akifumi Kushiyama, Toshiaki Fukushima, Sonoko Kumamoto, Takanori Shinjo, Hideaki Kamata, Fusanori Nishimura and Tomoichiro Asano
- Journal Title
  
  Adipocyte
  
  Volume: 2 Pages: 28-32
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-24657092
[Journal Article] Integrator complex plays anessential role inadipose differentiation2013
- Author(s)
  Y. Otani, Y. Nakatsu, H. Sakoda, T. Fukushima, M. Fujishiro, A. Kushiyama, H. Okubo, Y. Tsuchiya, H. Ohno, S. Takahashi, F. Nishimura, H. Kamata, H. Katagiri, T. Asano
- Journal Title
  
  Biochem. Biophys. Res. Commun.
  
  Volume: 434 Pages: 197-202
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-24657092
[Journal Article] Resistin-Like Moleculeβ Is Abundantly Expressed in Foam Cells Is Involved in Atherosclerosis Development2013
- Author(s)
  Akifumi Kushiyama, Hideyuki Sakoda, Naohide Oue, Masamichi Okubo, Yusuke Nakatsu, Haruya Ono, Toshiaki Fukushima, Hideaki Kamata, Fusanori Nishimura, Takako Kikuchi, Midori Fujishiro, Koichi Nishiyama, Hiroyuki Aburatani, Sakura Kushiyama, Masaki Iizuka, Naoyuki Taki, Jeffrey Encinas, Kazuhiro Sentani, Narumi Ogonuki, Atsuo Ogura, Shoji Kawazu, Wataru Yasui, Yukihito Higashi, Hiroki Kurihara, Hideki Katagiri, Tomoichiro Asano
- Journal Title
  
  Arteriosclerosis, Thrombosis, Vascular Biology
  
  Volume: 33 Pages: 1986-1993
- Peer Reviewed
- Data Source
  KAKENHI-PLANNED-20117012
[Journal Article] Lactobacillus casei strain Shirota protects against non-alcoholic steatohepatitis development in a rodent model2013
- Author(s)
  Hirofumi Okubo, Hideyuki Sakoda, Akifumi Kushiyama, Midori Fujishiro, Yusuke Nakatsu, Toshiaki Fukushima, Yasuka Matsunaga, Hideaki Kamata, Takashi Asahara, Yasuto Yoshida, Osamu Chonan, Misaki Iwashita, Fusanori Nishimura Tomoichiro Asano
- Journal Title
  
  American Journal Physiolgy-Gastrointestinal Liver Physiogy
  
  Volume: 305 Pages: 911-918
- Peer Reviewed
- Data Source
  KAKENHI-PLANNED-20117012
[Journal Article] Lactobacillus casei strain Shirota protects against non-alcoholic steatohepatitis development in a rodent model2013
- Author(s)
  Okubo H, Sakoda H, Kushiyama A, Fujishiro M, Nakatsu Y, Fukushima T, Matsunaga Y, Kamata H, Asahara T, Yoshida Y, Chonan O, Iwashita M, Nishimura F, Asano T
- Journal Title
  
  American Journal Physiolgy-Gastrointestinal and Liver Physiogy
  
  Volume: 305 Issue: 12 Pages: 911-918
- DOI
  10.1152/ajpgi.00225.2013
- Peer Reviewed
- Data Source
  KAKENHI-PLANNED-20117012, KAKENHI-PROJECT-23370062, KAKENHI-PROJECT-24591314, KAKENHI-PROJECT-24591315, KAKENHI-PROJECT-24657092, KAKENHI-PROJECT-24790928, KAKENHI-PROJECT-25461372
[Journal Article] Par14 associates with IRS-1, thereby enhancing insulin-induced IRS-1 phosphorylation metabolic actions2013
- Author(s)
  Jun Zhang, Yusuke Nakatsu, Takanori Sinjo, Ying Guo, Hideyuki Sakoda, Takeshi Yamamotoya, Yuichiro Otani, Hirofumi Okubo, Akifumi Kushiyama, Midori Fujishiro, Toshiaki Fukushima, Yoshihiro Tsuchiya, Hideaki Kamata, Fusanori Tsuchiya, Hideaki Kamata, Fusanori Nishimura, Hideki Katagiri, Shin-ichiro Takahashi, Hiroki Kurihara, Takafumi Uchida, Tomoichiro Asano
- Journal Title
  
  Journal of Biological Chemistry
  
  Volume: 288 Pages: 20692-20701
- Peer Reviewed
- Data Source
  KAKENHI-PLANNED-20117012
[Journal Article] Par14 associates with IRS-1, thereby enhancing insulin-induced IRS-1 phosphorylation and metabolic actions.2013
- Author(s)
  Zhang J, Nakatsu Y, Sinjo T, Guo Y, Sakoda H, Yamamotoya T, Otani Y, Okubo H, Kushiyama A, Fujishiro M, Fukushima T, Tsuchiya Y, Kamata H, Nishimura F, Katagiri H, Takahashi SI, Kurihara H, Uchida T, Asano T.
- Journal Title
  
  Ｊournal of Biological Chemistry
  
  Volume: 288 Issue: 28 Pages: 20692-20701
- DOI
  10.1074/jbc.m113.485730
- Peer Reviewed
- Data Source
  KAKENHI-PLANNED-20117012, KAKENHI-PROJECT-23370062, KAKENHI-PROJECT-24591314, KAKENHI-PROJECT-24591315, KAKENHI-PROJECT-24657092, KAKENHI-PROJECT-24790928, KAKENHI-PROJECT-25461372
[Journal Article] Resistin-Like Molecule β Is Abundantly Expressed in Foam Cells and Is Involved in Atherosclerosis Development.2013
- Author(s)
  Kushiyama A, Sakoda H, Oue N, Okubo M, Nakatsu Y, Ono H, Fukushima T, Kamata H, Nishimura F, Kikuchi T, Fujishiro M, Nishiyama K, Aburatani H, Kushiyama S, Iizuka M, Taki N, Encinas J, Sentani K, Ogonuki N, Ogura A, Kawazu S, Yasui W, Higashi Y, Kurihara H, Katagiri H, Asano T.
- Journal Title
  
  Arteriosclerosis, Thrombosis, and Vascular Biology
  
  Volume: 33 Issue: 8 Pages: 1986-1993
- DOI
  10.1161/atvbaha.113.301546
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PLANNED-20117012, KAKENHI-PROJECT-23370062, KAKENHI-PROJECT-23591099, KAKENHI-PROJECT-23659107, KAKENHI-PROJECT-23791047, KAKENHI-PROJECT-24249047, KAKENHI-PROJECT-24591314, KAKENHI-PROJECT-24591315, KAKENHI-PROJECT-24657092, KAKENHI-PROJECT-24790928, KAKENHI-PUBLICLY-25111705, KAKENHI-PROJECT-25460416, KAKENHI-PROJECT-25461372, KAKENHI-PROJECT-25670762
[Journal Article] Valsartan, independently of AT1 receptor or PPARγ, suppresses LPS-induced macrophage activation and improves insulin resistance in cocultured adipocytes.2012
- Author(s)
  M. Iwashita, H. Sakoda, A. Kushiyama, M. Fujishiro, H. Kamata, T. Asano, et.al.
- Journal Title
  
  Am. J. Physiol. Endocrinol. Metab.
  
  Volume: 302 Pages: 286-296
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-24657092
[Journal Article] Angiotensin receptor 1 blocker valsartan normalizes gene expression profiles of 3T3-L1 adipocytes altered by co-culture with LPS-treated RAW264.7 macrophages2012
- Author(s)
  Kumamoto S, Kushiyama A, Nakatsu Y, Sakoda H, Fujishiro M, Iwashita M, Ohno H, Zhang J, Guo Y, Aburatani H, Kamata H, Nishimura F, Asano T.
- Journal Title
  
  Obesity Research and Clinical Practice
  
  Volume: 6 Issue: 4 Pages: 288-297
- DOI
  10.1016/j.orcp.2012.05.005
- Peer Reviewed
- Data Source
  KAKENHI-PLANNED-20117012, KAKENHI-PROJECT-21390556, KAKENHI-PROJECT-23370062, KAKENHI-PROJECT-24792328
[Journal Article] LST8 level controls basal p70 S6 kinase and Akt phosphorylations, and mTORC1 and mTORC2 negatively regulate each other by competing for association with LST8.2012
- Author(s)
  Kikuchi T, Zhang J, Sakoda H, Koketsu Y, Fujishiro M, Kushiyama A, Nakatsu Y, Kamata H, Inoki K, Takahashi S, Kurihara H, Hideki K, Oka Y, Asano T
- Journal Title
  
  Obesity Research and Clinical Practice
  
  Volume: 6 Issue: 3 Pages: 175-262
- DOI
  10.1016/j.orcp.2011.10.002
- Peer Reviewed
- Data Source
  KAKENHI-PLANNED-20117012, KAKENHI-PROJECT-22790847, KAKENHI-PROJECT-23370062
[Journal Article] Role of Pin1 in the pathogenesis of non-alcoholic steatohepatitis in a rodent model2012
- Author(s)
  Yusuke Nakatsu, Yuichiro Otani, Hideyuki Sakoda, Jun Zhang, Ying Guo, Hirofumi Okubo, Akifumi Kushiyama, Midori Fujishiro, Takako Kikuch, Toshiaki Fukushima, Haruya Ohno, Yoshihiro Tsuchiya, Hideaki Kamata, Akiko Nagamachi, Toshiya Inaba, Fusanori Nishimura, Hideki Katagiri, Shin-ichiro Takahashi, Hiroki Kurihara, Takafumi Uchida, Tomoichiro Asano
- Journal Title
  
  Journal of Biological Chemistry
  
  Volume: 287 Pages: 44526-44535
- Peer Reviewed
- Data Source
  KAKENHI-PLANNED-20117012
[Journal Article] Angiotensin receptor 1 blocker valsartan normalizes gene expression profiles of 3T3-L1 adipocytes altered by co-culture with LPS-treated RAW264.7 macrophages2012
- Author(s)
  S. Kumamoto, A. Kushiyama, Y. Nakatsu, H. Sakoda, M. Fujishiro, M. Iwashita, H. Ohno, J. Zhang, Y. Guo, H. Aburatani, H. Kamata, F. Nishimura, and T. Asano
- Journal Title
  
  Obes. Res. Clin. Pract.
  
  Volume: 6 Pages: 288-297
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-24657092
[Journal Article] Valsartan, independently of AT1 receptor or PPARγ, suppresses LPS-induced macrophage activation improves insulin resistance in cocultured adipocytes2012
- Author(s)
  Misaki Iwashita, Hideyuki Sakoda, Akifumi Kushiyama, Midori Fujishiro, Haruya Ohno, Yusuke Nakatsu, Toshiaki Fukushima, Sonoko Kumamoto, Yoshihiro Tsuchiya, Takako Kikuchi, Hiroki Kurihara, Hiroshi Akazawa, Issei Komuro, Hideaki Kamata, Fusanori Nishimura, Tomoichiro Asano
- Journal Title
  
  American Journal of Physiology-Endocrinology Metabolism
  
  Volume: 302 Pages: 286-296
- Data Source
  KAKENHI-PLANNED-20117012
[Journal Article] 活性酸素によるリン酸化シグナルの制御と炎症・発がん2012
- Author(s)
  鎌田英明
- Journal Title
  
  実験医学増刊
  
  Volume: Vol.30 Pages: 2786-2792
- Data Source
  KAKENHI-PLANNED-20117012
[Journal Article] Role of Pin1 in the pathogenesis of non-alcoholic steatohepatitis in a rodent mode2012
- Author(s)
  Y. Nakatsu, Y. Otani, H. Sakoda, J. H. Kamata, A. T. Asano, et.al.
- Journal Title
  
  J. Biol. Chem.
  
  Volume: 287 Pages: 44526-44535
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-24657092
[Journal Article] Angiotensin receptor 1 blocker valsartan normalizes gene expression profiles of 3T3-L1 adipocytes altered by co-culture with LPS-treated RAW264.7 macrophages2012
- Author(s)
  Sonoko Kumamoto, Akifumi Kushiyama, Yusuke Nakatsu, Hideyuki Sakoda, Midori Fujishiro, Misaki Iwashita, Haruya Ohno, Jun Zhang, Ying Guo, Hiroyuki Aburatani, Hideaki Kamata, Fusanori Nishimura, Tomoichiro Asano
- Journal Title
  
  Obesity Research & Clinical Practice
  
  Volume: 6 Pages: 288-297
- Peer Reviewed
- Data Source
  KAKENHI-PLANNED-20117012
[Journal Article] Promotion of DNA repair by nuclear IKKβ phosphorylation of ATM in response to genotoxic stimuli.2012
- Author(s)
  Kei Sakamoto, et al.
- Journal Title
  
  Oncogene
  
  Volume: 32 Issue: 14 Pages: 1854-1862
- DOI
  10.1038/onc.2012.192
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-11J11187, KAKENHI-PROJECT-22300317, KAKENHI-PROJECT-23370062, KAKENHI-PROJECT-24657092
[Journal Article] Valsartan, independently of AT1 receptor or PPARγ, suppresses LPS-induced macrophage activation and improves insulin resistance in cocultured adipocytes.2012
- Author(s)
  Iwashita M, Sakoda H, Kushiyama A, Fujishiro M, Ohno H, Nakatsu Y, Fukushima T, Kumamoto S, Tsuchiya Y, Kikuchi T, Kurihara H, Akazawa H, Komuro I, Kamata H, Nishimura F, Asano T.
- Journal Title
  
  American Journal of Physiology - Endocrinology and Metabolism
  
  Volume: 302 Issue: 3 Pages: 286-296
- DOI
  10.1152/ajpendo.00324.2011
- Peer Reviewed
- Data Source
  KAKENHI-PLANNED-20117012, KAKENHI-PROJECT-21390556, KAKENHI-PROJECT-22780249, KAKENHI-PROJECT-22790847, KAKENHI-PROJECT-23370062, KAKENHI-PROJECT-23390213, KAKENHI-PROJECT-23791047, KAKENHI-PROJECT-23870022, KAKENHI-PROJECT-24790928
[Journal Article] 発癌・神経細胞の生死に関わる細胞内ROS シグナル2012
- Author(s)
  鎌田英明,上原孝
- Journal Title
  
  細胞工学(秀潤社)
  
  Volume: Vol.31 Pages: 165-170
- Data Source
  KAKENHI-PLANNED-20117012
[Journal Article] Role of Pin1 in the pathogenesis of non-alcoholic steatohepatitis in a rodent model2012
- Author(s)
  Nakatsu Y, Otani Y, Sakoda H, Zhang J, Guo Y, Okubo H, Kushiyama A, Fujishiro M, Kikuchi T, Fukushima T, Ohno H, Tsuchiya Y, Kamata H, Nagamachi A, Inaba T, Nishimura F, Katagiri H, Takahashi SI, Kurihara H, Uchida T, Asano T
- Journal Title
  
  J Biol Chem
  
  Volume: 287 Issue: 53 Pages: 44526-44535
- DOI
  10.1074/jbc.m112.397133
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-21390556, KAKENHI-PUBLICLY-23013007, KAKENHI-PROJECT-23370062, KAKENHI-PROJECT-23659107, KAKENHI-PROJECT-23791047, KAKENHI-PROJECT-23870022, KAKENHI-PROJECT-24249047, KAKENHI-PROJECT-24591314, KAKENHI-PROJECT-24591315, KAKENHI-PROJECT-24790928
[Journal Article] Peptidyl-prolyl cis/trans isomerase NIMA-interacting 1 associates with IRS-1 and enhances insulin actions and adipogenesis.2011
- Author(s)
  Nakatsu, Y., Sakoda, H., Kushiyama, A., Zhang, J., Ono, H., Fujishiro, M., Kikuchi, T., Fukushima, T., Yoneda, M., Ohno, H., Horike, N., Kanna, M., Tsuchiya, Y., Kamata, H., Nishimura, F., Isobe, T., Ogihara, T., Katagiri, H., Oka, Y., Takahashi, S., Kurihara, H., Uchida, T., Asano, T.
- Journal Title
  
  J.Biol.Chem 286
  
  Pages: 20812-20822
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-21570141
[Journal Article] 4F2hc stabilizes GLUT1 protein increases glucose transport activity2011
- Author(s)
  Haruya Ohno, Yusuke Nakatsu, Hideyuki Sakoda, Akifumi Kushiyama, Hiraku Ono, Midori Fujishiro, Yuichiro Otani, Hirofumi Okubo, Masayasu Yoneda, Toshiaki Fukushima, Yoshihiro Tsuchiya, Hideaki Kamata, Fusanori Nishimura, Hiroki Kurihara, Hideki Katagiri, Yoshitomo Oka, Tomoichiro Asano
- Journal Title
  
  American Journal of Physiology ; Cell Physiology
  
  Volume: 300 Pages: 1047-1054
- Peer Reviewed
- Data Source
  KAKENHI-PLANNED-20117012
[Journal Article] On off system for PI3-kinase Akt signaling through S-nitrosylation of phosphatase with sequence homology to tensin (PTEN)2011
- Author(s)
  Naoki Numajiria, Kumi Takasawa, Tadashi Nishiy, Hirotaka Tanaka, Kazuki Ohno, Wataru Hayakawa, Mariko Asada, Hiromi Matsuda, Kaoru Azumi, Hideaki Kamata, Tomohiro Nakamura, Hideaki Hara, Masabumi Minami, Stuart A. Lipton, Takashi Uehara
- Journal Title
  
  Poceedings of the National Academy of Sciences of the United States of America
  
  Volume: 108 Pages: 10349-10354
- Data Source
  KAKENHI-PLANNED-20117012
[Journal Article] Xanthine oxidoreductase is involved in macrophage foam cell formation atherosclerosis development2011
- Author(s)
  Akifumi Kushiyama, Hirofumi Okubo, Hideyuki Sakoda, Takako Kikuchi, Midori Fujishiro, Hirokazu Sato, Sakura Kushiyama, Misaki Iwashita, Fusanori Nishimura, Toshiaki Fukushima, Yusuke Nakatsu, Hideaki Kamata, Shoji Kawazu, Yukihito Higashi, Hiroki Kurihara, Tomoichiro Asano
- Journal Title
  
  Arteriosclerosis, Thrombosis, Vascular Biology
  
  Volume: 32 Pages: 291-298
- Peer Reviewed
- Data Source
  KAKENHI-PLANNED-20117012
[Journal Article] 4F2hc stabilizes GLUT1 protein and increases glucose transport activity.American Journal of Physiology2011
- Author(s)
  Haruya 0hno, Yusuke Nakatsu, Hideyuki Sakoda, Akifumi Kushiyama, Hiraku Ono, Midori Fujishiro, Yuichiro Otani, Hirofumi Okubo, Masayasu Yoneda, Toshiaki Fukushima, Yoshihiro Tsuchiya, Hideaki Kamata, Fusanori Nishimura, Hiroki Kurihara, Hideki Katagiri, Yoshitomo Oka, Tomoichiro Asano
- Journal Title
  
  Cell Physiolog 300
  
  Pages: 1047-1054
- Peer Reviewed
- Data Source
  KAKENHI-PLANNED-20117012
[Journal Article] 4F2hc stabilizes GLUT1 protein and increases glucose transport activity.2011
- Author(s)
  Ohno, H., Nakatsu, Y., Sakoda, H., Kushiyama, A., Ono, H., Fujishiro, M., Yuichiro Otani, Hirofumi Okubo, Yoneda, M., Fukushima, T., Tsuchiya, Y., Kamata, H., Nishimura, F., Kurihara, H., Katagiri, H., Oka, Y., Asano, T.
- Journal Title
  
  Am.J.Physiol.Cell Physiol. 300
  
  Pages: 1047-1054
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-21570141
[Journal Article] On-off system for PI3-kinase-Akt signaling through S-nitrosylation of phosphatase with sequence homology to tensin (PTEN).2011
- Author(s)
  Numajiria, N., Takasawa, K, Nishiy, T., Tanaka, H., Ohno, K., Hayakawa, W., Asada, M., Matsuda, H., Azumi, K.,Kamata, H.Tomohiro Nakamura, Hideaki Hara, Masabumi Minami, Stuart A.Lipton, Takashi Uehara.
- Journal Title
  
  Poc.Nat.Acad.Sci.USA. in press
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-21570141
[Journal Article] Peptidyl-prolyl cis/trans isomerase NIMA- interacting 1 associates with IRS-1 and enhances insulin actions and adipogenesis2011
- Author(s)
  Yusuke Nakatsu, Hideyuki Sakoda, Akifumi Kushiyama, Jun Zhang, Hiraku Ono, Midori Fujishiro, Takako Kikuchi, Toshiaki Fukushima, Masayasu Yoneda, Haruya Ohno, Nanao Horike, Machi Kanna, Yoshihiro Tsuchiya, Hideaki Kamata, Fusanori Nishimura, Toshiak Isobe, Takehide Ogihara, Hideki Katagiri, Yoshitomo Oka, Shin-ichiro Takahashi, Hiroki Kurihara, Takafumi Uchida, Tomoichiro Asano
- Journal Title
  
  Journal of Biological Chemistry 286
  
  Pages: 20812-20822
- Peer Reviewed
- Data Source
  KAKENHI-PLANNED-20117012
[Journal Article] On-off system for PI3-kinase-Akt signaling through S-nitrosylation of phosphatase with sequence homology to tensin (PTEN)2011
- Author(s)
  Numajiri N, Takasawa K, Nishiya T, Tanaka H, Ohno K, Hayakawa W, Asada M, Matsuda H, Azumi K, Kamata H, Nakamura T, Hara H, Minami M, Lipton SA, and Uehara T
- Journal Title
  
  Proc Natl Acad Sci USA
  
  Volume: 108 Pages: 10349-54
- Peer Reviewed
- Data Source
  KAKENHI-ORGANIZER-20117001
[Journal Article] Peptidyl-prolyl cis/trans isomerase NIMA-interacting 1 associates with IRS-1 enhances insulin actions adipogenesis2011
- Author(s)
  Yusuke Nakatsu, Hideyuki Sakoda, Akifumi Kushiyama, Jun Zhang, Hiraku Ono, Midori Fujishiro, Takako Kikuchi, Toshiaki Fukushima, Masayasu Yoneda, Haruya Ohno, Nanao Horike, Machi Kanna, Yoshihiro Tsuchiya, Hideaki Kamata, Fusanori Nishimura, Toshiak Isobe, Takehide Ogihara, Hideki Katagiri, Yoshitomo Oka, Shin-ichiro Takahashi, Hiroki Kurihara, Takafumi Uchida, Tomoichiro Asano
- Journal Title
  
  Journal of Biological Chemistry
  
  Volume: 286 Pages: 20812-20822
- Peer Reviewed
- Data Source
  KAKENHI-PLANNED-20117012
[Journal Article] IκBβ is a positive and negative regulator of NF-κB activity during inflammation2010
- Author(s)
  Hideaki Kamata, Yoshihiro Tsuchiya, Tomoichiro Asano
- Journal Title
  
  Cell Research 20
  
  Pages: 1178-1180
- Peer Reviewed
- Data Source
  KAKENHI-PLANNED-20117012
[Journal Article] Pinl associates with and induces translocation of CRTC2 to the cytosol, thereby suppressing CRE transcriptional activity2010
- Author(s)
  Yusuke Nakatsu, Hideyuki Sakoda, Akifumi Kushiyama, Hiraku Ono, Midori Fujishiro, Nanao Horike, Masayasu Yoneda, Haruya Ohno, Yoshihiro Tsuchiya, Hideaki Kamata, Hidetoshi Tahara, Toshiaki Isobe, Fusanori Nishimura, Hideki Katagiri, Yoshitomo Oka, Toshiaki Fukushima, Shin-Ichiro, Takahashi, Hiroki Kurihara, Takafumi Uchida, Tomoichiro Asano
- Journal Title
  
  Journal of Biological Chemistry 285
  
  Pages: 33018-33027
- Peer Reviewed
- Data Source
  KAKENHI-PLANNED-20117012
[Journal Article] Decreased SIRT1 expression LKB1 phosphorylation occurs with long-term high-fat diet feeding, in addition to AMPK phosphorylation impairment in the early phase2010
- Author(s)
  Masayasu Yoneda, Ying Guo, Haruya Ono, Yusuke Nakatsu, Jun Zhang, XingLong Cui, Misaki Iwashita, Sonoko Kumamoto, Yoshihiro Tsuchiya, Hideyuki Sakoda, Midori Fujishiro, Akifumi Kushiyama, Yuko Koketsu, Takako Kikuchi, Hideaki Kamata, Fusanori Nishimura,Tomoichiro Asano
- Journal Title
  
  Obesity Research Clinical Practice
  
  Volume: 4 Pages: 201-207
- Peer Reviewed
- Data Source
  KAKENHI-PLANNED-20117012
[Journal Article] Nuclear IKKbeta is an adaptor protein for IkappaBalpha ubiquitination and degradation in UV-induced NF-kappaB activation2010
- Author(s)
  Tsuchiya, Y., Asano, T., Nakayama, K., Kato, T.Jr., Karin, M., Kamata, H.
- Journal Title
  
  Mol.Cell 39
  
  Pages: 570-582
- Peer Reviewed
- Data Source
  KAKENHI-ORGANIZER-20117001
[Journal Article] IκBβ is a positive and negative regulator of NF-κB activity during inflammation.2010
- Author(s)
  Kamata, H., Tsuchiya, Y., Asano, T.
- Journal Title
  
  Cell Res. 20
  
  Pages: 1178-1180
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-21570141
[Journal Article] IκBβ is a positive negative regulator of NF-κB activity during inflammation2010
- Author(s)
  Hideaki Kamata, Yoshihiro Tsuchiya, Tomoichiro Asano
- Journal Title
  
  Cell Research
  
  Volume: 20 Pages: 1178-1180
- Peer Reviewed
- Data Source
  KAKENHI-PLANNED-20117012
[Journal Article] IKKβis an adaptor protein for β-TrCP mediated IκBα ubiquitination in UV-induced NF-κB activation.2010
- Author(s)
  Tsuchiya, Y., Asano, T., Nakayama, K., Kato, Jr., K., Karin, M., Kamata, H.
- Journal Title
  
  Mol.Cell 39
  
  Pages: 570-582
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-21570141
[Journal Article] Macrophage foam cell formation is augmented in serum from patients with diabetic angiopathy2010
- Author(s)
  Xinglong Cui, Akifumi Kushiyama, Masayasu Yoneda, Yusuke Nakatsu, Ying Guo, Jun Zhang, Haruya Ono, Machi Kanna, Hideyuki Sakoda, Hiraku Ono, Takako Kikuchi, Midori Fujishiro, Masashi Shiomi, Hideaki Kamata, Hiroki Kurihara, Masatoshi Kikuchi, Shoji Kawazu, Fusanori Nishimura, Tomoichiro Asano
- Journal Title
  
  Diabetes Research Clinical Practice
  
  Volume: 87 Pages: 57-63
- Peer Reviewed
- Data Source
  KAKENHI-PLANNED-20117012
[Journal Article] IκBβ is a positive and negative regulator of NF-κB activity during inflammation2010
- Author(s)
  Hideaki Kamata, et.al.
- Journal Title
  
  Cell Res.
  
  Volume: 20 Pages: 1178-1180
- Peer Reviewed
- Data Source
  KAKENHI-PLANNED-20117012
[Journal Article] Nuclear IKKbeta is an adaptor protein for IkappaBalpha ubiquitination and degradation in UV-induced NF-kappaB activation2010
- Author(s)
  Tsuchiya Y, Asano T, Nakayama K, Kato T, Jr., Karin M, and Kamata H
- Journal Title
  
  Mol Cell
  
  Volume: 39 Pages: 570-82
- Peer Reviewed
- Data Source
  KAKENHI-ORGANIZER-20117001
[Journal Article] Nuclear IKKβ is an adaptor protein for IκBα ubiquitination and degradation in UV-induced NF-κB activation.2010
- Author(s)
  Tsuchiya, Y., Asano, T., Nakayama, K., Kato, T., Karin, M., Kamata, H.
- Journal Title
  
  Molecular Cell 39(4)
  
  Pages: 570-82
- NAID
  120002737833
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-20390258
[Journal Article] Pin1 associates with and induces translocation of CRTC2 to the cytosol, thereby suppressing CRE transcriptional activity.2010
- Author(s)
  Nakatsu, Y., Sakoda, H., Kushiyama, A., Ono, H., Fujishiro, M., Horike, N., Yoneda, M., Ohno, H., Tsuchiya, Y., Kamata, H., Hidetoshi Tahara, Toshiaki Isobe, Nishimura, F., Katagiri, H., Oka, Y., Fukushima, T., Takahashi, S., Kurihara, H., Uchida, T., Asano, T.
- Journal Title
  
  J.Biol.Chem. 285
  
  Pages: 33018-33027
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-21570141
[Journal Article] IKKβ is an adaptor protein for β-TrCP mediated IкBα ubiquitination in UV-induced NF-кB activation2010
- Author(s)
  Yoshihiro Tsuchiya, Tomoichiro Asano, Keiko Nakayama, Tomohisa Kato Jr., Michael Karin, Hideaki Kamata
- Journal Title
  
  Molecular Cell
  
  Volume: 39 Pages: 570-582
- Peer Reviewed
- Data Source
  KAKENHI-PLANNED-20117012
[Journal Article] IκBβ is a positive and negative regulator of NF-κB activity during inflammation2010
- Author(s)
  Hideaki Kamata
- Journal Title
  
  Cell Research
  
  Volume: 20 Pages: 1178-1180
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-21570141
[Journal Article] IκBβ is a positive and negative regulator of NF-κB activity during inflammation.2010
- Author(s)
  Kamata, H., Tsuchiya, Y., Asano, T.
- Journal Title
  
  Cell Res. 20
  
  Pages: 1178-1180
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-20390258
[Journal Article] Nuclear IKKβ is an adaptor protein for IκBα ubiquitination and degradation in UV-induced NF-κB activation2010
- Author(s)
  Tsuchiya, Y., Asano, T., Nakayama, K., Kato, T., Karin, M., Kamata, H.
- Journal Title
  
  Molecular Cell
  
  Volume: 39 Pages: 570-82
- NAID
  120002737833
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-20390258
[Journal Article] Macrophage foam cell formation is augmented in serum from patients with diabetic angiopathy.2010
- Author(s)
  Cui X., Kushiyama A., Yoneda M., Nakatsu Y., Guo Y., Zhang J., Ono H., Kanna M., Sakoda H., Ono H., Kikuchi T., Fujishiro M., Shiomi M., Kamata H., Kurihara H., Kikuchi M., Kawazu S., Nishimura F., Asano T.
- Journal Title
  
  DiabetesRes.Clin.Pract. 87
  
  Pages: 57-63
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-21570141
[Journal Article] IKKβ is an adaptor protein for β-TrCP mediated IKBα ubiquitination in UV-induced NF-κB activation2010
- Author(s)
  Yoshihiro Tsuchiya, Tomoichiro Asano, Keiko Nakayama, Tomohisa Kato Jr., Michael Karin, Hideaki Kamata
- Journal Title
  
  Molecular Cell 39
  
  Pages: 570-582
- Peer Reviewed
- Data Source
  KAKENHI-PLANNED-20117012
[Journal Article] IκBβ is a positive and negative regulator of NFκB activity during inflammation.2010
- Author(s)
  Kamata, H., Tsuchiya, Y., Asano T.
- Journal Title
  
  Cell Res.
  
  Volume: 20 Pages: 1178-80
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-20390258
[Journal Article] Pin1 associates with induces translocation of CRTC2 to the cytosol, thereby suppressing CRE transcriptional activity2010
- Author(s)
  Yusuke Nakatsu, Hideyuki Sakoda, Akifumi Kushiyama, Hiraku Ono, Midori Fujishiro, Nanao Horike, Masayasu Yoneda, Haruya Ohno, Yoshihiro Tsuchiya, Hideaki Kamata, Hidetoshi Tahara, Toshiaki Isobe, Fusanori Nishimura, Hideki Katagiri, Yoshitomo Oka, Toshiaki Fukushima, Shin-Ichiro Takahashi, Hiroki Kurihara, Takafumi Uchida, Tomoichiro AsanoYusuke Nakatsu, Hideyuki Sakoda, Akifumi Kushiyama, Hiraku Ono, Midori Fujishiro, Nanao Horike, Masayasu Yoneda, Haruya Ohno, Yoshihiro Tsuchiya, Hideaki Kamata, Hidetoshi Tahara, Toshiaki Isobe, Fusanori Nishimura, Hideki Katagiri, Yoshitomo Oka, Toshiaki Fukushima, Shin-Ichiro Takahashi, Hiroki Kurihara, Takafumi Uchida, Tomoichiro Asano
- Journal Title
  
  Journal of Biological Chemistry
  
  Volume: 285 Pages: 33018-33027
- Peer Reviewed
- Data Source
  KAKENHI-PLANNED-20117012
[Journal Article] Decreased SIRT1 expression and LKB1 phosphorylation occurs with long-term high-fat diet feeding, in addition to AMPK phosphorylation impairment in the early phase.2010
- Author(s)
  Yoneda M., Guo Y., Ono H., Nakatsu Y., Zhang J., Cui X., Iwashita M., Kumamoto S., Tsuchiya Y., Sakoda H., Fujishiro M., Kushiyama A., Koketsu Y., Kikuchi T., Kamata H., Nishimura F., Asano T.
- Journal Title
  
  Obes.Res.Clin.Pract. 4
  
  Pages: 201-207
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-21570141
[Journal Article] 活性酸素によるリン酸化シグナル制御2009
- Author(s)
  鎌田英明
- Journal Title
  
  実験医学増刊:活性酸素シグナルと酸化ストレス 27
  
  Pages: 2366-2372
- Data Source
  KAKENHI-PROJECT-21570141
[Journal Article] 活性酸素によるリン酸化シグナル制御2009
- Author(s)
  鎌田英明
- Journal Title
  
  実験医学増刊:活性酸素シグナルと酸化ストレス 27
  
  Pages: 2366-2372
- Data Source
  KAKENHI-PLANNED-20117012
[Journal Article] 活性酸素によるリン酸化シグナル制御2009
- Author(s)
  鎌田英明
- Journal Title
  
  実験医学増刊
  
  Volume: Vol.27 Pages: 2366-2372
- Data Source
  KAKENHI-PLANNED-20117012
[Journal Article] Regulation of gut-derived resistin-like molecule beta expression by nutrients.2008
- Author(s)
  Junko Fujio, Akifumi Kushiyama, Hideyuki Sakoda, Midori Fujishiro, Takehide Ogihara, Yasushi Fukushima, Motonobu Anai, Nanao Hor ike, Hideaki Kamata, Yasunobu Uchijima, Hiroki Kurihara, Tomoichiro Asano
- Journal Title
  
  Diabetes Res Clin Pract. 79
  
  Pages: 2-10
- Description
  「研究成果報告書概要(欧文)」より
- Data Source
  KAKENHI-PROJECT-18570136
[Journal Article] Long-term Forskolin Stimulation Induces AMPK Activation and Thereby Enhances Tight Junction Formation in Human Placental Trophoblast BeWo Cells.2008
- Author(s)
  Egawa, M., Kamata, H., Sakoda, H., Fujishiro M., Asano, T.
- Journal Title
  
  Placenta 29
  
  Pages: 1003-1008
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-20390258
[Journal Article] Hepatic overexpression of a doninant negative form of raptor enhances Akt phosphorylation and restores insulin sensitivity in K/KAy mice.2008
- Author(s)
  Yuko Koketsu, Hideyuki Sakoda, Midori Fujishiro, Akifurni Kushiyama, Yasushi Fukushima, Hiraku Ono, Motonobu Anai, Takako Kikuchi, Takeshi Fukuda, Hideaki Kamata, Nanao Hor ike, Yasunobu Uchijima, Hiroki Kurihara, Tomoichiro Asano
- Journal Title
  
  Am J Physiol Endocrinol Metab. 294(4)
- Description
  「研究成果報告書概要(欧文)」より
- Data Source
  KAKENHI-PROJECT-18570136
[Journal Article] Long-term Forskolin Stimulation Induces AMPK Activation and There by Enhances Tight Junction Formation in Human Placental Trophobla st BeWo Cells2008
- Author(s)
  Egawa, M., Kamata, H., Asano, T., et al.
- Journal Title
  
  Placenta 29
  
  Pages: 1003-1008
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-20390258
[Journal Article] Suppression of AP-1 Activity by Cycloprodigiosin Hydrochloride.2007
- Author(s)
  Keiko Kawauchi, Kei Tobiume, Shuhei Kaneko, Keiko Kaneshiro, Shiho Okamoto, Emi Ueda, Hideaki Kamata, Yoshinori Moriyama, Hajime Hirata
- Journal Title
  
  Biol. Pharm. Bull. 30(9)
  
  Pages: 1792-1795
- NAID
  110006380271
- Description
  「研究成果報告書概要(欧文)」より
- Data Source
  KAKENHI-PROJECT-18570136
[Journal Article] Role of Phosphatidylinositol 3-Kinase Activation on Insulin Action and Its Alteration in Diabetic Conditions.2007
- Author(s)
  Tomoichiro Asano, Midori Fujishiro, Akifumi Kushiyama, Yusuke Nakatsu, Masayasu Yoneda, Hideaki Kamata, Hideyuki Sakoda
- Journal Title
  
  Biol. Pharm. Bull. 30(9)
  
  Pages: 1610-1616
- NAID
  110006380237
- Description
  「研究成果報告書概要(欧文)」より
- Data Source
  KAKENHI-PROJECT-18570136
[Journal Article] Carboxyl-terminal modulator protein (ctmp) induces akt phosphorylation and activation, thereby enhancing anti-apoptotic, glycogen synthetic and glucose uptake pathways.2007
- Author(s)
  Hiraku Ono, Hideyuki Sakoda, Midori Fujishiro, Motonobu Anai, Akifumi Kushiyama, Yasushi Fukushima, Hideki Katagiri, Takehide Ogihara, Yoshitomo Oka, Hideaki Kamata, Nanao Horike, Yasunobu Uchijima, Hiroki Kurihara, Tomoichiro Asano
- Journal Title
  
  Am J Physiol Cell Physiol. 293(5)
- Description
  「研究成果報告書概要(欧文)」より
- Data Source
  KAKENHI-PROJECT-18570136
[Journal Article] インスリンシグナルと2型糖尿病2006
- Author(s)
  浅野知一郎, 鎌田英明
- Journal Title
  
  遺伝子医学MOOK 6
  
  Pages: 255-259
- Description
  「研究成果報告書概要(和文)」より
- Data Source
  KAKENHI-PROJECT-18570136
[Journal Article] インスリンシグナルと2型糖尿病2006
- Author(s)
  浅野知一郎, 鎌田英明
- Journal Title
  
  遺伝子医学MOOK 6; シグナル伝達病を知る 6
  
  Pages: 255-259
- Description
  「研究成果報告書概要(和文)」より
- Data Source
  KAKENHI-PROJECT-16570121
[Journal Article] 活性線素によるチロシンホスフアターゼの調節2006
- Author(s)
  鎌田英明
- Journal Title
  
  分子細胞治療 5
  
  Pages: 28-34
- Description
  「研究成果報告書概要(和文)」より
- Data Source
  KAKENHI-PROJECT-18570136
[Journal Article] The E3 ubiquitin ligase Itch couples JNK activation to TNF-induced cell death by inducing c-FLIPL turnover.2006
- Author(s)
  Lufen Chang, Hideaki Kamata, Giovanni Solinas, Jun-Li Luo, Shin Maeda, K Venuprasad, Yun-Cai Liu, Michael Karin.
- Journal Title
  
  Cell. 124
  
  Pages: 601-613
- Description
  「研究成果報告書概要(欧文)」より
- Data Source
  KAKENHI-PROJECT-16570121
[Journal Article] 活性線素によるチロシンホスファターゼの調節2006
- Author(s)
  鎌田英明
- Journal Title
  
  分子細胞治療 5
  
  Pages: 28-34
- Data Source
  KAKENHI-PROJECT-18570136
[Journal Article] 血糖調節における視床下部ピルビン酸代謝の役割2006
- Author(s)
  米田真康, 鎌田英明, 浅野知一郎
- Journal Title
  
  Annual Review 糖尿病・代謝・内分泌
  
  Pages: 20-23
- Description
  「研究成果報告書概要(和文)」より
- Data Source
  KAKENHI-PROJECT-18570136
[Journal Article] The E3 ubiquitin I igase Itch couples JNK activation to TNF-induced cell death by inducing c-FLIPL turnover.2006
- Author(s)
  Lufen Chang, Hideaki Kamata, Giovanni Solinas, Jun-Li Luo, Shin Maeda, K Venuprasad, Yun-Cai Liu, Michael Karin.
- Journal Title
  
  Cell. 124
  
  Pages: 601-613
- Description
  「研究成果報告書概要(欧文)」より
- Data Source
  KAKENHI-PROJECT-18570136
[Journal Article] 活性線素によるチロシンホスファターゼの調節.2006
- Author(s)
  鎌田英明
- Journal Title
  
  分子細胞治療(先端医学社) 5
  
  Pages: 28-34
- Description
  「研究成果報告書概要(和文)」より
- Data Source
  KAKENHI-PROJECT-16570121
[Journal Article] Reactive oxygen species promote TNFα-induced cell death and sustained JNK activation by oxidizing MAP kinase phosphatases2005
- Author(s)
  Hideaki Kamata et al.
- Journal Title
  
  Cell 120
  
  Pages: 649-661
- Description
  「研究成果報告書概要(和文)」より
- Data Source
  KAKENHI-PROJECT-16570121
[Journal Article] TNFαの細胞死誘導における持続的JNK活性化機構とROSの役割.2005
- Author(s)
  鎌田英明
- Journal Title
  
  細胞工学 24
  
  Pages: 602-603
- Description
  「研究成果報告書概要(和文)」より
- Data Source
  KAKENHI-PROJECT-16570121
[Journal Article] Redox regulation of nerve growth factor-induced neuronal differentiation of PC12 cells through modulation of the nerve growth factor receptor, TrkA.2005
- Author(s)
  Hideaki Kamata et al.
- Journal Title
  
  Archives of Biochemistry and Biophysics 434
  
  Pages: 16-25
- Description
  「研究成果報告書概要(和文)」より
- Data Source
  KAKENHI-PROJECT-16570121
[Journal Article] Reactive oxygen species promote TNFa-induced death and sustained JNK activation by inhibiting MAP kinase phosphatase2005
- Author(s)
  Hideaki Kamata, et al.
- Journal Title
  
  Cell 120
  
  Pages: 649-661
- Data Source
  KAKENHI-PROJECT-16570121
[Journal Article] Redox regulation of nerve growth factor-induced neuronal differentiation of PC12 cells through modulation of the nerve growth factor receptor, TrkA.2005
- Author(s)
  Hideaki Kamata, Shin-ichi Oka, Yukinao Shibukawa, Jungo Kakuta, Hajime Hirata
- Journal Title
  
  Archives of Biochemistry and Biophysics 434
  
  Pages: 16-25
- Description
  「研究成果報告書概要(欧文)」より
- Data Source
  KAKENHI-PROJECT-16570121
[Journal Article] IKKβ couples hepatocyte cell death to cytokine-driven compensatory proliferation that promotes chemical hepatocarcinogenesis.2005
- Author(s)
  Shin Maeda, Hideaki Kamata, Jun-Li Luo, Hyam Leffert, Michael Karin.
- Journal Title
  
  Cell. 121
  
  Pages: 977-990
- Description
  「研究成果報告書概要(欧文)」より
- Data Source
  KAKENHI-PROJECT-16570121
[Journal Article] IKK/NF-kappaB signaling : balancing life and death- a new approach to cancer therapy.2005
- Author(s)
  Jun-Li Luo, Hideaki Kamata, Michael Karin.
- Journal Title
  
  Journal of Clinical Investigation. 115
  
  Pages: 2625-2632
- Description
  「研究成果報告書概要(欧文)」より
- Data Source
  KAKENHI-PROJECT-16570121
[Journal Article] Reactive oxygen species promote TNFa-induced death and sustained JNK actrvation by inhibitina MAP kinase phosphatase2005
- Author(s)
  Hideaki Kamata, et al.
- Journal Title
  
  Cell 120
  
  Pages: 649-661
- Data Source
  KAKENHI-PROJECT-16570121
[Journal Article] Redox regulation of nerve growth factor-induced neuronal differentiation of PC12 cells through modulation of the nerve growth factor receptor, TrkA.2005
- Author(s)
  Hideaki Kamata, et al.
- Journal Title
  
  Archives of Biochemistry and Biophysics 434
  
  Pages: 16-25
- Data Source
  KAKENHI-PROJECT-16570121
[Journal Article] シグナル伝達のレドックス制御-シグナル伝達のメディエーターとしての活性酸素とプロテインチロシンホスファターゼ2005
- Author(s)
  鎌田英明
- Journal Title
  
  医学のあゆみ別冊(未定)
- Data Source
  KAKENHI-PROJECT-16570121
[Journal Article] 活性酸素種(ROS)によるJNKの持続的活性化のメカニズムとTNFαによる細胞死2005
- Author(s)
  鎌田英明
- Journal Title
  
  実験医学 23
  
  Pages: 1920-1923
- Description
  「研究成果報告書概要(和文)」より
- Data Source
  KAKENHI-PROJECT-16570121
[Journal Article] シグナル伝達のレドックス制御-シグナル伝達のメディエーターとしての活性酸素とプロテインチロシンホスファターゼ.2005
- Author(s)
  鎌田英明
- Journal Title
  
  別冊「医学のあゆみ」レドックス-ストレス防御の医学
  
  Pages: 2681-2686
- Description
  「研究成果報告書概要(和文)」より
- Data Source
  KAKENHI-PROJECT-16570121
[Journal Article] The Anti-Death Machinery in IKK/NF-kappaB Signaling.2005
- Author(s)
  Jun-Li Luo, Hideaki Kamata, Michael Karin.
- Journal Title
  
  Journal of Clinical Immunology. 25
  
  Pages: 541-550
- Description
  「研究成果報告書概要(欧文)」より
- Data Source
  KAKENHI-PROJECT-16570121
[Journal Article] Reactive oxygen species promote TNFα-induced cell death and sustained JNK activation by oxidizing MAP kinase phosphatases2005
- Author(s)
  Hideaki Kamata, Shi-ichi Honda, Shin Maeda, Lufen Chang, Hajime Hirata, Michael Karin.
- Journal Title
  
  Cell. 120
  
  Pages: 649-661
- Description
  「研究成果報告書概要(欧文)」より
- Data Source
  KAKENHI-PROJECT-16570121
[Journal Article] A PLCδ1-binding protein, p122RhoGAP, is localized in focal adhesions.2004
- Author(s)
  Katsuhisa Kawai, Masaki Yamaga, Yumi lwamae, M.Kiyota, Hideaki Kamata, Hajime Hirata, Yoshimi Homma, Hitoshi Yagisawa.
- Journal Title
  
  Biochemical Society Transactions. 32
  
  Pages: 1107-1109
- Description
  「研究成果報告書概要(欧文)」より
- Data Source
  KAKENHI-PROJECT-16570121
[Journal Article] A PLCdelta1-binding protein, p122/RhoGAP, is localized in caveolin-enriched membrane domains and regulates caveolin internalization2004
- Author(s)
  Masaki Yamaga, Hideaki Kamata et al.
- Journal Title
  
  Gene to Cell 9
  
  Pages: 25-37
- Data Source
  KAKENHI-PROJECT-16570121
[Journal Article] A PLCdelta(1)-binding protein, p122RhoGAP, is localized in focal adhesions.2004
- Author(s)
  Katsuhisa Kawai, Hideaki Kamata et al.
- Journal Title
  
  Biochem Soc Trans. 32
  
  Pages: 1107-1109
- Data Source
  KAKENHI-PROJECT-16570121
[Journal Article] 血糖調節における視床下部ピルビン酸代謝の役割2004
- Author(s)
  米田真康, 鎌田英明, 浅野知一郎
- Journal Title
  
  Annual Review 糖尿病・代謝・内分泌
  
  Pages: 20-23
- Description
  「研究成果報告書概要(和文)」より
- Data Source
  KAKENHI-PROJECT-16570121
[Journal Article] On-off system for PI3-kinase-Akt signaling through S-nitrosylation of PTEN
- Author(s)
  Numajiri, N, Takasawa, K, Nishiya, T, Tanaka, H, Ohno, K., Hayakawa, W., Asada, M., Matsuda, H., Azumi, K., Kamata, H., Nakamura, T., Hara, H., Minami, M., Lipton, S.A., Uehara, T
- Journal Title
  
  Proc.Natl.Acad.Sci.USA in press
- Peer Reviewed
- Data Source
  KAKENHI-ORGANIZER-20117001
[Presentation] IKKβ遺伝子の改変により生じた肝臓における慢性炎症は遺伝子発現の改変を介して化学発がんを抑制する2017
- Author(s)
  土谷佳弘、金井昭教、金輪真佐美、外丸祐介、前田愼、鎌田英明
- Organizer
  2017年度生命科学系学会合同年次大会（ConBio2017）
- Data Source
  KAKENHI-PROJECT-16K18419
[Presentation] Suppression of chemical hepatocarcinogenesis in transgenic mice expressing nuclear-localized kinase negative IKKβ2016
- Author(s)
  土谷佳弘, 松永泰花, 外丸祐介, 前田愼, 鎌田英明.
- Organizer
  第75回日本癌学会学術総会
- Place of Presentation
  横浜
- Year and Date
  2016-10-06
- Data Source
  KAKENHI-PROJECT-16K18419
[Presentation] Suppression of chemical hepatocarcinogenesis in transgenic mice expressing nuclar-localized kinase negative IKKb2016
- Author(s)
  土谷佳弘, 松永泰花, 外丸祐介, 前田愼, 鎌田英明
- Organizer
  第75回日本癌学会学術総会
- Place of Presentation
  横浜
- Year and Date
  2016-10-06
- Data Source
  KAKENHI-PUBLICLY-15H01406
[Presentation] 転写因子RelAのトランス活性化ドメインはIkBキナーゼのリン酸化を制御してNF-kBとオートファジーのシグナル系のハブとして機能する2016
- Author(s)
  鎌田英明
- Organizer
  第39回日本分子生物学会
- Place of Presentation
  横浜
- Year and Date
  2016-11-30
- Invited
- Data Source
  KAKENHI-PUBLICLY-15H01382
[Presentation] 肝細胞特異的ＩＫＫb遺伝子改変マウスにおける酸化ストレスと細胞死の発生と肝細胞がんの抑制2016
- Author(s)
  土谷佳弘, 松永泰花, 外丸祐介, 前田愼, 鎌田英明
- Organizer
  第89回日本生化学大会
- Place of Presentation
  仙台
- Year and Date
  2016-09-26
- Data Source
  KAKENHI-PUBLICLY-15H01382
[Presentation] 肝細胞特異的IKKβ遺伝子改変マウスにおける酸化ストレスと肝細胞がんの抑制と細胞死の発生と肝細胞がんの抑制2016
- Author(s)
  土谷佳弘, 松永泰花, 外丸祐介, 前田愼,　鎌田英明,
- Organizer
  第89回日本生化学大会, 仙台, 2016.9.26
- Place of Presentation
  仙台
- Year and Date
  2016-09-25
- Data Source
  KAKENHI-PROJECT-16K18419
[Presentation] 肝細胞特異的ＩＫＫb遺伝子改変マウスにおける酸化ストレスと細胞死の発生と肝細胞がんの抑制2016
- Author(s)
  土谷佳弘, 松永泰花, 外丸祐介, 前田愼, 鎌田英明
- Organizer
  第89回日本生化学大会
- Place of Presentation
  仙台
- Year and Date
  2016-09-26
- Data Source
  KAKENHI-PUBLICLY-15H01406
[Presentation] 転写因子RelAのトランス活性化ドメインはIkBキナーゼのリン酸化を制御してNF-kBとオートファジーのシグナル系のハブとして機能する2016
- Author(s)
  鎌田英明
- Organizer
  第39回日本分子生物学会
- Place of Presentation
  横浜
- Year and Date
  2016-11-30
- Invited
- Data Source
  KAKENHI-PUBLICLY-15H01406
[Presentation] Suppression of chemical hepatocarcinogenesis in transgenic mice expressing nuclar-localized kinase negative IKKb2016
- Author(s)
  土谷佳弘, 松永泰花, 外丸祐介, 前田愼, 鎌田英明
- Organizer
  第75回日本癌学会学術総会
- Place of Presentation
  横浜
- Year and Date
  2016-10-06
- Data Source
  KAKENHI-PUBLICLY-15H01382
[Presentation] IKKβ遺伝子改変マウスにおける肝線維化誘導と肝がん抑制機構2016
- Author(s)
  土谷佳弘, 松永泰花, 中津祐介, 鎌田英明
- Organizer
  第39回日本分子生物学年会
- Place of Presentation
  横浜
- Year and Date
  2016-11-30
- Data Source
  KAKENHI-PROJECT-16K18419
[Presentation] RelAの転写活性化ドメインを介したIKK活性制御機構2015
- Author(s)
  土谷佳弘　樋口徹　松永泰花　高橋江奈　中津祐介　浅野知一郎　鎌田英明
- Organizer
  第38回日本分子生物学会第87回日本生化学会大会合同大会
- Place of Presentation
  神戸
- Year and Date
  2015-12-01
- Data Source
  KAKENHI-PUBLICLY-15H01406
[Presentation] 計画的細胞死にともなう細胞内レドックスと小胞輸送系の改変2015
- Author(s)
  樋口徹　土谷佳弘　金本麻裕　高橋江奈　中津祐介　浅野知一郎　鎌田英明
- Organizer
  第38回日本分子生物学会第87回日本生化学会大会合同大会
- Place of Presentation
  神戸
- Year and Date
  2015-12-01
- Data Source
  KAKENHI-PUBLICLY-15H01382
[Presentation] 非アルコール性肝炎におけるLUBAC形成障害の解析2015
- Author(s)
  松永泰花　中津祐介　福嶋俊明　大久保博史　岩下未咲　迫田秀之　藤城緑　山本屋武　櫛山暁史　高橋伸一郎　土谷佳弘　鎌田英明　徳永文稔　岩井一宏　浅野知一郎
- Organizer
  第38回日本分子生物学会第87回日本生化学会大会合同大会
- Place of Presentation
  神戸
- Year and Date
  2015-12-01
- Data Source
  KAKENHI-PUBLICLY-15H01382
[Presentation] 計画的細胞死にともなう細胞内レドックスと小胞輸送系の改変2015
- Author(s)
  樋口徹　土谷佳弘　金本麻裕　高橋江奈　中津祐介　浅野知一郎　鎌田英明
- Organizer
  第38回日本分子生物学会第87回日本生化学会大会合同大会
- Place of Presentation
  神戸
- Year and Date
  2015-12-01
- Data Source
  KAKENHI-PUBLICLY-15H01406
[Presentation] 非アルコール性肝炎におけるLUBAC形成障害の解析2015
- Author(s)
  松永泰花　中津祐介　福嶋俊明　大久保博史　岩下未咲　迫田秀之　藤城緑　山本屋武　櫛山暁史　高橋伸一郎　土谷佳弘　鎌田英明　徳永文稔　岩井一宏　浅野知一郎
- Organizer
  第38回日本分子生物学会第87回日本生化学会大会合同大会
- Place of Presentation
  神戸
- Year and Date
  2015-12-01
- Data Source
  KAKENHI-PUBLICLY-15H01406
[Presentation] RelAの転写活性化ドメインを介したIKK活性制御機構2015
- Author(s)
  土谷佳弘　樋口徹　松永泰花　高橋江奈　中津祐介　浅野知一郎　鎌田英明
- Organizer
  第38回日本分子生物学会第87回日本生化学会大会合同大会
- Place of Presentation
  神戸
- Year and Date
  2015-12-01
- Data Source
  KAKENHI-PUBLICLY-15H01382
[Presentation] 膵β細胞機能におけるプロリン異性化酵素Pin1の役割2014
- Author(s)
  中津祐介、森馨一、松永泰花、福嶋俊明、鎌田英明、山口賢、石原寿光、浅野知一郎
- Organizer
  第37回日本分子生物学会
- Place of Presentation
  横浜
- Year and Date
  2014-11-27
- Data Source
  KAKENHI-PROJECT-23370062
[Presentation] RelAによる遺伝子発現非依存的なIKKβ活性制御機構2014
- Author(s)
  土谷佳弘、浅野知一郎、鎌田英明
- Organizer
  第87回日本生化学会大会
- Place of Presentation
  京都
- Year and Date
  2014-10-18
- Data Source
  KAKENHI-PROJECT-23370062
[Presentation] 活性酸素応答ホスファターゼに連関した細胞シグナル制御機構2014
- Author(s)
  鎌田英明
- Organizer
  臨床フリーラジカル会議
- Place of Presentation
  京都
- Year and Date
  2014-12-06
- Data Source
  KAKENHI-PROJECT-24657092
[Presentation] RelAによる遺伝子発現非依存的なIKKβ活性制御機構2014
- Author(s)
  土谷佳弘、浅野知一郎、鎌田英明
- Organizer
  第37回日本分子生物学会
- Place of Presentation
  横浜
- Year and Date
  2014-11-26
- Data Source
  KAKENHI-PROJECT-24657092
[Presentation] ユビキチンリガーゼNedd4がIRS-2を介したIGFシグナルを増強する新しい分子機構2014
- Author(s)
  福嶋俊明、吉原英人、吉田遥佳、伯野史彦、佐伯泰、中津祐介、鎌田英明、高橋伸一郎、浅野知一郎
- Organizer
  第37回日本分子生物学会
- Place of Presentation
  横浜
- Year and Date
  2014-11-26
- Data Source
  KAKENHI-PROJECT-24657092
[Presentation] 膵β細胞機能におけるプロリン異性化酵素Pin1の役割2014
- Author(s)
  中津祐介、森馨一、松永泰花、福嶋俊明、鎌田英明、山口賢、石原寿光、浅野知一郎
- Organizer
  第37回日本分子生物学会
- Place of Presentation
  横浜
- Year and Date
  2014-11-26
- Data Source
  KAKENHI-PROJECT-24657092
[Presentation] キサンチンオキシダーゼ阻害剤FebuxostatによるNASH改善作用の検討2014
- Author(s)
  松永泰花、中津祐介、瀬野康之、片迫彩、金岡龍平、福嶋俊明、鎌田英明、浅野知一郎
- Organizer
  第37回日本分子生物学会
- Place of Presentation
  横浜
- Year and Date
  2014-11-26
- Data Source
  KAKENHI-PROJECT-24657092
[Presentation] ユビキチンリガーゼNedd4がIRS-2を介したIGFシグナルを増強する新しい分子機構2014
- Author(s)
  福嶋俊明、吉原英人、吉田遥佳、伯野史彦、佐伯泰、中津祐介、鎌田英明、高橋伸一郎、浅野知一郎
- Organizer
  第37回日本分子生物学会
- Place of Presentation
  横浜
- Year and Date
  2014-11-26
- Data Source
  KAKENHI-PROJECT-23370062
[Presentation] 活性酸素応答ホスファターゼに連関した細胞シグナル制御機構2014
- Author(s)
  鎌田英明
- Organizer
  第31回　臨床フリーラジカル会議
- Place of Presentation
  京都
- Year and Date
  2014-12-06
- Data Source
  KAKENHI-PROJECT-23370062
[Presentation] RelAによる遺伝子発現非依存的なIKKβ活性制御機構2014
- Author(s)
  土谷佳弘、浅野知一郎、鎌田英明
- Organizer
  第37回日本分子生物学会
- Place of Presentation
  横浜
- Year and Date
  2014-11-26
- Data Source
  KAKENHI-PROJECT-23370062
[Presentation] RelAによる遺伝子発現非依存的なIKKβ活性制御機構2014
- Author(s)
  土谷佳弘、浅野知一郎、鎌田英明
- Organizer
  第87回日本生化学会大会
- Place of Presentation
  京都
- Year and Date
  2014-10-18
- Data Source
  KAKENHI-PROJECT-24657092
[Presentation] キサンチンオキシダーゼ阻害剤FebuxostatによるNASH改善作用の検討2014
- Author(s)
  松永泰花、中津祐介、瀬野康之、片迫彩、金岡龍平、福嶋俊明、鎌田英明、浅野知一郎
- Organizer
  第37回日本分子生物学会
- Place of Presentation
  横浜
- Year and Date
  2014-11-26
- Data Source
  KAKENHI-PROJECT-23370062
[Presentation] TNFに応答したRIP1/RIP3複合体形成における活性酸素種(ROS)の関与と細胞の生と死の制御2013
- Author(s)
  金本麻裕, 土谷佳弘, 浅野知一郎, 鎌田英明
- Organizer
  第36回日本分子生物学会
- Place of Presentation
  神戸
- Year and Date
  2013-12-04
- Data Source
  KAKENHI-PLANNED-20117012
[Presentation] 腫瘍壊死因子(TNF)に応答したネクロプトーシス誘導キナーゼRIP-3の細胞外分泌による細胞死の制御2013
- Author(s)
  金本麻裕, 土谷佳弘, 浅野知一郎, 鎌田英明
- Organizer
  第86回日本生化学会合同大会
- Place of Presentation
  横浜
- Year and Date
  2013-09-13
- Data Source
  KAKENHI-PLANNED-20117012
[Presentation] 非アルコール性脂肪肝炎発症におけるLUBAC の形成の解析2013
- Author(s)
  松永泰花,中津祐介,福嶋俊明,大久保博史,迫田秀之,土谷佳弘,鎌田英明,徳永文稔,岩井一宏,浅野知一郎
- Organizer
  第36回日本分子生物学会
- Place of Presentation
  神戸
- Year and Date
  2013-12-04
- Data Source
  KAKENHI-PLANNED-20117012
[Presentation] 転写活性非依存性のRelA によるIKKβ活性制御機2013
- Author(s)
  土谷佳弘, 金本麻裕, 浅野知一郎, 鎌田英明
- Organizer
  第36回日本分子生物学会
- Place of Presentation
  神戸
- Year and Date
  2013-12-05
- Data Source
  KAKENHI-PLANNED-20117012
[Presentation] Nedd4-IRS2複合体の形成機構とこの複合体が前立腺がん細胞の過増殖に果たす役割2013
- Author(s)
  福嶋俊明,吉原英人,古田遥佳,伯野史彦,千田和広,佐伯泰,田中啓二,伊藤昭博,田稔,中津祐介,鎌田英明,高橋伸一郎,浅野知一郎
- Organizer
  第36回日本分子生物学会
- Place of Presentation
  神戸
- Year and Date
  2013-12-05
- Data Source
  KAKENHI-PLANNED-20117012
[Presentation] ストレス応答による核内IKKβを介したNF-κB活性化と細胞死2013
- Author(s)
  土谷佳弘, 金本麻裕, 浅野知一郎, 鎌田英明
- Organizer
  第86回日本生化学会合同大会
- Place of Presentation
  横浜
- Year and Date
  2013-09-13
- Data Source
  KAKENHI-PLANNED-20117012
[Presentation] プロリン異性化酵素Pin1による新規AMPK 機能制御機構の解明2013
- Author(s)
  中津祐介,岩下未咲,松永泰花,福嶋俊明,迫田秀之,櫛山暁史,鎌田英明,内田隆史,高橋伸一郎,浅野知一郎
- Organizer
  第36回日本分子生物学会
- Place of Presentation
  神戸
- Year and Date
  2013-12-04
- Data Source
  KAKENHI-PLANNED-20117012
[Presentation] 腫瘍壊死因子(TNFα)に応答した細胞死とRIP1とRIP3の発現変化2012
- Author(s)
  金本麻裕, 土谷佳弘, 浅野知一郎, 鎌田英明
- Organizer
  第85回日本生化学会合同大会
- Place of Presentation
  福岡
- Year and Date
  2012-12-16
- Data Source
  KAKENHI-PLANNED-20117012
[Presentation] TNFに連関したシグナル系のレドックス制御と細胞死2012
- Author(s)
  鎌田英明
- Organizer
  第85回日本生化学会合同大会シンポジウム
- Place of Presentation
  福岡
- Year and Date
  2012-12-15
- Data Source
  KAKENHI-PLANNED-20117012
[Presentation] Nuclear IKKβ acts as an adaptor protein for IкBα ubiquitination degradation in UV-oxidative stress-induced NF-кB activation2012
- Author(s)
  Yoshihiro Tsuchiya, Tomoichiro Asano, Keiko Nakayama, Tomohisa Kato, Jr., Michael Karin, Hideaki Kamata
- Organizer
  Keystone Symposium, " NF-kappaB Signaling Biology : From Bench to Bedside "
- Place of Presentation
  Whistler, British Columbia, Canada
- Year and Date
  2012-03-25
- Data Source
  KAKENHI-PLANNED-20117012
[Presentation] IKKβの脱リン酸化反応における転写因子RelAの関与2012
- Author(s)
  土谷佳弘, 金本麻裕, 菅野雅元, 浅野知一郎, 鎌田英明
- Organizer
  第85回日本生化会合同大会ワークショップ
- Place of Presentation
  福岡
- Year and Date
  2012-12-16
- Data Source
  KAKENHI-PLANNED-20117012
[Presentation] Stress-induced NF-kB activation mediated by the nuclear IKK cell death2012
- Author(s)
  土谷佳弘, 金本麻裕, 菅野雅元, 浅野知一郎, 鎌田英明
- Organizer
  第35回日本分子生物学会
- Place of Presentation
  福岡
- Year and Date
  2012-12-13
- Data Source
  KAKENHI-PLANNED-20117012
[Presentation] 転写因子NF-κBの活性化機構と細胞の生と死の制御2011
- Author(s)
  鎌田英明
- Organizer
  第48回広島大学・生命科学フォーラム
- Place of Presentation
  東広島(招待講演)
- Year and Date
  2011-11-11
- Data Source
  KAKENHI-PROJECT-23370062
[Presentation] 肥満、脂肪肝およびNASH発症におけるプロリンイソメラーゼPin1の関与2011
- Author(s)
  中津祐介, 張君, 福島俊明, 迫田秀之, 櫛山暁史, 藤城緑, 大野晴也, 大久保博史, 大谷裕一郎, 福島俊明, 鎌田英明, 内田隆史, 浅野知一郎
- Organizer
  第52回日本生化学会中国四国支部会
- Place of Presentation
  広島
- Year and Date
  2011-05-14
- Data Source
  KAKENHI-PLANNED-20117012
[Presentation] プロリン異性化酵素Par14とPin1のインスリンシグナルと糖・脂質代謝における役割2011
- Author(s)
  浅野知一郎,中津祐介,山本屋武,藤城緑,櫛山暁史,郭瑩,張君,福嶋俊明,鎌田英明,栗原裕基, 内田隆史, 迫田秀之
- Organizer
  第34回日本分子生物学会年会
- Place of Presentation
  横浜
- Year and Date
  2011-12-14
- Data Source
  KAKENHI-PLANNED-20117012
[Presentation] IKKβの多重的活性制御機構ー転写因子p65によるネガティブフィードバックとレドックス制御の関与2011
- Author(s)
  土谷佳弘, 浅野知一郎, 菅野雅元,鎌田英明
- Organizer
  第34回日本分子生物学会年会
- Place of Presentation
  横浜
- Year and Date
  2011-12-16
- Data Source
  KAKENHI-PLANNED-20117012
[Presentation] 転写因子NF-κBの活性化機構と細胞の生と死の制御2011
- Author(s)
  鎌田英明
- Organizer
  第48回広島大学・生命科学フォーラム
- Place of Presentation
  東広島(招待講演)
- Year and Date
  2011-11-11
- Data Source
  KAKENHI-PLANNED-20117012
[Presentation] Nuclear IKKβ phosphrylates ATM in response to genotoxic stimuli, which promotes DNA repair.2011
- Author(s)
  Kei Sakamoto, Yohko Hikiba, Yoshihiro Hirata, Masao Akanuma, Hideaki Kamata Shin Maeda
- Organizer
  第34回日本分子生物学会年会ワークショップ
- Place of Presentation
  横浜
- Year and Date
  2011-12-15
- Data Source
  KAKENHI-PLANNED-20117012
[Presentation] Nedd4によるインスリン受容体基質(IRS)のユビキチン化はインスリン・IGF-Iシグナルを増強する2011
- Author(s)
  福島俊明, 吉原英人, 伯野史彦, 佐伯泰, 田中啓二, 伊藤昭博, 中津祐介, 鎌田英明, 高橋伸一郎, 浅野知一郎
- Organizer
  第52回日本生化学会中国四国支部会
- Place of Presentation
  広島
- Year and Date
  2011-05-14
- Data Source
  KAKENHI-PLANNED-20117012
[Presentation] Ubiquitin-like domain(ULD)内におけるL353A変異体を用いたIKKbetaタンパク質分解機構の解析2011
- Author(s)
  金本麻裕, 土谷佳弘, 浅野知一郎, 鎌田英明
- Organizer
  第84回日本生化学会大会
- Place of Presentation
  京都
- Year and Date
  2011-09-22
- Data Source
  KAKENHI-PLANNED-20117012
[Presentation] IKKβ act as an adaptor protein for IκBα ubiquitination and degradation in UV-induced NF-κB activation possible involvement in the TNF signaling2011
- Author(s)
  Yoshihiro Tsuchiya , Hideaki Kamata
- Organizer
  13th International TNF Conference, Awajishima
- Place of Presentation
  Japan
- Year and Date
  2011-05-17
- Data Source
  KAKENHI-PLANNED-20117012
[Presentation] IKKβ act as an adaptor protein for IκBα ubiquitination degradation in UV-induced NF-κB activation ; possible involvement in the TNF signaling2011
- Author(s)
  Yoshihiro Tsuchiya Hideaki Kamata
- Organizer
  13th International TNF Conference
- Place of Presentation
  Awajishima, Japan
- Year and Date
  2011-05-17
- Data Source
  KAKENHI-PLANNED-20117012
[Presentation] 非アルコール性脂肪性肝炎発症におけるプロリン異性化酵素Pin1の役割2011
- Author(s)
  中津祐介, 張君, 大久保博史, 福嶋俊明, 迫田秀之, 櫛山暁史, 鎌田英明, 内田隆史, 浅野知一郎
- Organizer
  第84回日本生化学会大会
- Place of Presentation
  京都
- Year and Date
  2011-09-24
- Data Source
  KAKENHI-PLANNED-20117012
[Presentation] 肝細胞においてNedd4はインスリン受容体基質(IRS)-2のユビキチン化を介してインスリンシグナルを増強する2011
- Author(s)
  福嶋俊明, 吉原英人, 伯野史彦, 佐伯泰, 田中啓二, 伊藤昭博, 中津祐介, 鎌田英明, 高橋伸一郎, 浅野知一郎
- Organizer
  第84回日本生化学会大会
- Place of Presentation
  京都
- Year and Date
  2011-09-23
- Data Source
  KAKENHI-PLANNED-20117012
[Presentation] 非アルコール性脂肪性肝炎発症における肝および血球系細胞のプロリン異性化酵素Pin1の役割2011
- Author(s)
  中津祐介, 張君, 大久保博史, 福島俊明, 迫田秀之, 藤城緑, 櫛山暁史, 高橋伸一郎, 鎌田英明, 栗原裕基,内田隆史, 浅野知一郎
- Organizer
  第34回日本分子生物学会年会
- Place of Presentation
  横浜
- Year and Date
  2011-12-14
- Data Source
  KAKENHI-PLANNED-20117012
[Presentation] IKKβ act as an adaptor protein for Iκ Bαubiquitination and degradation in UV-induced NF-κB activation ; possible involvement in the TNF signaling.2011
- Author(s)
  土谷佳弘, 鎌田英明
- Organizer
  13th International TNF Conference
- Place of Presentation
  Awajishima,Japan
- Year and Date
  2011-05-17
- Data Source
  KAKENHI-PROJECT-21570141
[Presentation] エネルギー状態によるCRTC3の発現制御と脂肪分化における役割の解明2010
- Author(s)
  中津祐介, 迫田秀之, 櫛山暁史, 張君, 福嶋俊明, 内田隆史, 鎌田英明, 浅野知一郎
- Organizer
  第33回日本分子生物学会・第83回日本生化学会合同大会
- Place of Presentation
  神戸
- Year and Date
  2010-12-10
- Data Source
  KAKENHI-PROJECT-21570141
[Presentation] 新規Pin1結合タンパク質Trk-fused geneはAktの活性化を促進する2010
- Author(s)
  大崎慶子, 中津祐介, 迫田秀之, 櫛山暁史, 大野晴也, 渡辺俊明, 内田隆史, 福嶋俊明, 鎌田英明, 浅野知一郎
- Organizer
  第33回日本分子生物学会・第83回日本生化学会合同大会
- Place of Presentation
  神戸
- Year and Date
  2010-12-10
- Data Source
  KAKENHI-PROJECT-21570141
[Presentation] Nuclear IKKb acts as an adaptor protein for IκBα degradation in UV-induced NF-κB activation2010
- Author(s)
  鎌田英明
- Organizer
  第69回日本癌学会学術総会
- Place of Presentation
  大阪(招待講演)
- Year and Date
  2010-09-24
- Data Source
  KAKENHI-PROJECT-21570141
[Presentation] Nuclear IKKb acts as an adaptor protein for IkBa degradation in UV-induced NF-kB activation and promotes cell death2010
- Author(s)
  Hideaki Kamata
- Organizer
  International Symposium on the Innovation for Health And Sustainable Life
- Place of Presentation
  Hiroshima University
- Year and Date
  2010-03-09
- Data Source
  KAKENHI-PLANNED-20117012
[Presentation] 細胞内ストレスに応答した核内IKKβを介した新規NF-κB活性化機構2010
- Author(s)
  土谷佳弘, 浅野知一郎, 鎌田英明
- Organizer
  第33回日本分子生物学会・第83回日本生化学会合同大会
- Place of Presentation
  神戸
- Year and Date
  2010-12-09
- Data Source
  KAKENHI-PROJECT-21570141
[Presentation] Nuclear IKKb acts as an adaptor protein for IkBa degradation in UV-induced NF-kB activation and promotes cell death2010
- Author(s)
  Hideaki Kamata
- Organizer
  International Symposium on the Innovation for Health And Sustainable Life
- Place of Presentation
  Hiroshima University
- Year and Date
  2010-03-09
- Data Source
  KAKENHI-PROJECT-21570141
[Presentation] 新規Pin1結合タンパク質Trk-fused geneはAktの活性化を促進する2010
- Author(s)
  大崎慶子, 中津祐介, 迫田秀之, 櫛山暁史, 大野晴也, 渡辺俊明, 内田隆史, 福嶋俊明, 鎌田英明, 浅野知一郎
- Organizer
  第33回日本分子生物学会・第83回日本生化学会合同大会
- Place of Presentation
  神戸
- Year and Date
  2010-12-10
- Data Source
  KAKENHI-PLANNED-20117012
[Presentation] Nuclear IKKb acts as an adaptor protein for IκBα degradation in UV-induced NF-κB activation2010
- Author(s)
  鎌田英明, 土谷佳弘
- Organizer
  第69回日本癌学会学術総会
- Place of Presentation
  シンポジウム,大阪
- Year and Date
  2010-09-24
- Data Source
  KAKENHI-PROJECT-21570141
[Presentation] NF-κBと活性酸素(ROS)シグナルに連関したタンパク質のリン酸化と分解による細胞応答2010
- Author(s)
  鎌田英明, 土谷佳弘, 浅野知一郎
- Organizer
  第33回日本分子生物学会・第83回日本生化学会合同大会
- Place of Presentation
  神戸
- Year and Date
  2010-12-09
- Data Source
  KAKENHI-PROJECT-21570141
[Presentation] Nuclear IKKb acts as an adaptor protein for IκBα degradation in UV-induced NF-κB activation and promotes cell death.2010
- Author(s)
  鎌田英明
- Organizer
  International Symposium on the Innovation for Health And Sustainable Life Hiroshima University
- Place of Presentation
  Japan
- Year and Date
  2010-03-09
- Data Source
  KAKENHI-PROJECT-21570141
[Presentation] NF-κBと活性酸素(ROS)シグナルに連関したタンパク質のリン酸化と分解による細胞応答2010
- Author(s)
  鎌田英明
- Organizer
  第33回日本分子生物学会・第83回日本生化学会合同大会
- Place of Presentation
  神戸(招待講演)
- Year and Date
  2010-12-09
- Data Source
  KAKENHI-PROJECT-21570141
[Presentation] NF-κBと活性酸素(ROS)シグナルに連関したタンパク質のリン酸化と分解による細胞応答2010
- Author(s)
  鎌田英明
- Organizer
  第33回日本分子生物学会・第83回日本生化学会合同大会
- Place of Presentation
  神戸市(招待講演)
- Year and Date
  2010-12-09
- Data Source
  KAKENHI-PLANNED-20117012
[Presentation] 細胞内ストレスに応答した核内IKK?を介した新規NFкB活性化機構2010
- Author(s)
  土谷佳弘, 浅野知一郎, 鎌田英明
- Organizer
  第33回日本分子生物学会・第83回日本生化学会合同大会
- Place of Presentation
  神戸
- Year and Date
  2010-12-09
- Data Source
  KAKENHI-PLANNED-20117012
[Presentation] Nuclear IKKβ acts as an adaptor protein for IκBα degradation in UV-induced NF-κB activation2010
- Author(s)
  鎌田英明
- Organizer
  第69回日本癌学会学術総会
- Place of Presentation
  大阪市(招待講演)
- Year and Date
  2010-09-24
- Data Source
  KAKENHI-PLANNED-20117012
[Presentation] Nuclear IKKb acts as an adaptor protein for IκBα degradation in UV-induced NF-KB activation2010
- Author(s)
  鎌田英明, 土谷佳弘
- Organizer
  第69回日本癌学会学術総会
- Place of Presentation
  シンポジウム, 大阪
- Year and Date
  2010-09-24
- Data Source
  KAKENHI-PLANNED-20117012
[Presentation] NF-κBと活性酸素(ROS)シグナルに連関したタンパク質のリン酸化と分解による細胞応答2010
- Author(s)
  鎌田英明, 土谷佳弘, 浅野知一郎
- Organizer
  第33回日本分子生物学会・第83回日本生化学会合同大会
- Place of Presentation
  神戸
- Year and Date
  2010-12-09
- Data Source
  KAKENHI-PLANNED-20117012
[Presentation] Nuclear IKKβ acts as an adaptor protein for IкBα degradation in UV-induced NF-кB activation2010
- Author(s)
  鎌田英明, 土谷佳弘
- Organizer
  第69回日本癌学会学術総会
- Place of Presentation
  大阪
- Year and Date
  2010-09-24
- Data Source
  KAKENHI-PLANNED-20117012
[Presentation] 細胞内ストレスに応答した核内IKKRを介した新規NF-KB活性化機構2010
- Author(s)
  土谷佳弘, 浅野知一郎, 鎌田英明
- Organizer
  第33回日本分子生物学会・第83回日本生化学会合同大会
- Place of Presentation
  神戸
- Year and Date
  2010-12-09
- Data Source
  KAKENHI-PLANNED-20117012
[Presentation] Peptidyl prolyl cis/trans isomerase Pin1 interacts with CRTC2 regulates gluconeogenesis2010
- Author(s)
  Yusuke Nakatsu, Nanao Horike, Akifumi Kushiyama, Hideyuki Sakoda, Haruya Ohno, Machi Kanna, Hideaki Kamata, Hiroki Kurihara, Takafumi Uchida, Tomoichiro Asano
- Organizer
  70th Americiabetes Association
- Place of Presentation
  Orlo, Florida, USA
- Year and Date
  2010-06-27
- Data Source
  KAKENHI-PLANNED-20117012
[Presentation] 「エネルギー状態によるCRTC3の発現制御と脂肪分化における役割の解明2010
- Author(s)
  中津祐介, 迫田秀之, 櫛山暁史, 張君, 福嶋俊明, 内田隆史, 鎌田英明, 浅野知一郎
- Organizer
  第33回日本分子生物学会・第83回日本生化学会合同大会
- Place of Presentation
  神戸
- Year and Date
  2010-12-10
- Data Source
  KAKENHI-PLANNED-20117012
[Presentation] Nuclear IKKβ acts as an adaptor protein for IкBα degradation in UV-induced NF-кB activation promotes cell death2010
- Author(s)
  Hideaki Kamata
- Organizer
  International Symposium on the Innovation for Health Sustainable Life
- Place of Presentation
  Hiroshima University, Japan
- Year and Date
  2010-03-09
- Data Source
  KAKENHI-PLANNED-20117012
[Presentation] NF-κBと活性酸素(ROS)シグナルに連関したタンパク質のリン酸化と分解による細胞応答2010
- Author(s)
  鎌田英明, 土谷佳弘, 浅野知一郎
- Organizer
  第33回日本分子生物学会・第83回日本生化学会合同大会ワークショップ
- Place of Presentation
  神戸
- Year and Date
  2010-12-09
- Data Source
  KAKENHI-PLANNED-20117012
[Presentation] 核内IKKを介したNF-κB活性化による細胞死亢進2009
- Author(s)
  土谷佳弘, 浅野知一郎, 中山啓子, 加藤友久, Michael Karin, 鎌田英明
- Organizer
  第32回日本分子生物学会年会
- Place of Presentation
  横浜
- Year and Date
  2009-12-09
- Data Source
  KAKENHI-PROJECT-21570141
[Presentation] LPSによる脂肪組織インスリン抵抗性へのマクロファージの関与と,ARBによるインスリン抵抗性改善作用の機序2009
- Author(s)
  岩下未咲, 熊本園子, 迫田秀之, 櫛山暁史,藤城緑, 中津祐介, 大野晴也, 大谷裕一郎, 土谷佳弘, 鎌田英明, 西村英紀, 浅野知一郎
- Organizer
  第21回分子糖尿病学シンポジウム
- Place of Presentation
  和歌山
- Year and Date
  2009-12-12
- Data Source
  KAKENHI-PROJECT-21570141
[Presentation] プロリン異性化酵素Pin1はTORC2と結合してCRE活性を抑制することで,肝の糖新生系を制御する2009
- Author(s)
  中津祐介, 堀家なな緒, 櫛山暁史, 迫田秀之, 大野晴也, 神名真智, 鎌田英明, 栗原裕基, 内田隆史, 浅野知一郎
- Organizer
  第82回日本生化学会合同大会
- Place of Presentation
  神戸
- Year and Date
  2009-10-23
- Data Source
  KAKENHI-PROJECT-21570141
[Presentation] 細胞内ストレスに応答した核内IKKβを介した新規NF-κB活性化機構2009
- Author(s)
  土谷佳弘, 浅野知一郎, 中山啓子, 加藤友久, Michael Karin, 鎌田英明
- Organizer
  第82回日本生化学会合同大会
- Place of Presentation
  神戸
- Year and Date
  2009-10-23
- Data Source
  KAKENHI-PROJECT-21570141
[Presentation] 細胞内ストレスに応答した核内IKKβ を介した新規NF-кB活性化機構2009
- Author(s)
  土谷佳弘, 浅野知一郎, 中山啓子, 加藤友久, Michael Karin, 鎌田英明
- Organizer
  第82回日本生化学会
- Place of Presentation
  神戸
- Year and Date
  2009-10-23
- Data Source
  KAKENHI-PLANNED-20117012
[Presentation] 核内IKKを介したNF-кB活性化による細胞死亢進2009
- Author(s)
  土谷佳弘, 浅野知一郎, 中山啓子, 加藤友久, Michael Karin, 鎌田英明
- Organizer
  第32回日本分子生物学会年会
- Place of Presentation
  横浜
- Year and Date
  2009-12-09
- Data Source
  KAKENHI-PLANNED-20117012
[Presentation] Pin1 Binds to IRS-1, Functions as a Nutrient-Sensing Enhancer of Insulin Signaling2009
- Author(s)
  Yusuke Nakatsu, Hideyuki Sakoda, Akifumi Kushiyama, Midori Fujishiro, Masayasu Yoneda, Haruya Ohno, Hideaki Kamata, Takafumi Uchida, Tomoichiro Asano
- Organizer
  69th Americiabetes Association
- Place of Presentation
  New Orleans, Louisiana, USA
- Year and Date
  2009-06-08
- Data Source
  KAKENHI-PLANNED-20117012
[Presentation] GLUT1と相互作用を有する膜タンパク質4F2hcの同定と糖取り込みに与える影響2009
- Author(s)
  大野晴也, 中津祐介, 大久保博史, 大谷祐一郎, 崔興龍, 張君, 郭瑩, 迫田秀之, 藤城緑, 堀家なな緒, 櫛山暁史, 土谷佳弘, 鎌田英明, 浅野知一郎
- Organizer
  第82回日本生化学会合同大会
- Place of Presentation
  神戸
- Year and Date
  2009-10-24
- Data Source
  KAKENHI-PROJECT-21570141
[Presentation] 高脂肪食によるLKB1-AMPK・SIK-TORC2 pathway障害の分子機構2007
- Author(s)
  米田真康、大野晴也、迫田秀之、中津祐介、崔興龍、張君、郭瑩、江川真希子、鎌田英明、浅野知一郎
- Organizer
  第19回分子糖尿病学シンポジウム
- Place of Presentation
  神戸
- Year and Date
  2007-12-14
- Data Source
  KAKENHI-PROJECT-18570136
[Presentation] 高脂肪食によるLKBl-AMPK・SIK-T0RC2 pathway障害の分子機構2007
- Author(s)
  米田真康, 大野晴也, 迫田秀之, 中津祐介, 崔興龍, 張君, 郭螢, 江川真希子, 鎌田英明, 浅野知一郎
- Organizer
  第19回分子糖尿病学シンポジウム
- Place of Presentation
  神戸
- Year and Date
  2007-12-14
- Description
  「研究成果報告書概要(和文)」より
- Data Source
  KAKENHI-PROJECT-18570136
[Presentation] Oxidative stress forms disulfide bonds of IKK・/NEM0.2007
- Author(s)
  Kaori Natsuhara, Yoshihiro Tsuchiya, Tomoichiro Asano, Hideaki Kamata
- Organizer
  Annual Meeting of Japanese Biochemical Society
- Place of Presentation
  Yokohama
- Year and Date
  2007-12-14
- Description
  「研究成果報告書概要(欧文)」より
- Data Source
  KAKENHI-PROJECT-18570136
[Presentation] Functional analysis of IKK-independent degradation of I・B・ by TNF・.2007
- Author(s)
  Yoshihiro Tsuchiya, Kaori Natsuhara, Tomoichiro Asano, Hideaki Kamata
- Organizer
  Annual Meeting of Japanese Biochemical Society
- Place of Presentation
  Yokohama
- Year and Date
  2007-12-14
- Description
  「研究成果報告書概要(欧文)」より
- Data Source
  KAKENHI-PROJECT-18570136
[Presentation] 高脂防食によるLKBl-AMPK・SIK-T0RC2 pathway障害の分子機構2007
- Author(s)
  米田真康、大野晴也、迫田秀之、中津祐介、崔興龍、張君、郭瑩、江川真希子、鎌田英明、浅野知一郎
- Organizer
  第19回分子糖尿病学シンポジウム
- Place of Presentation
  神戸
- Year and Date
  2007-12-14
- Data Source
  KAKENHI-PROJECT-19044026
[Presentation] Redox regulation of cell life and death by MAP kinase phosphatase and PTEN.2007
- Author(s)
  Hideaki Kamata
- Organizer
  Redox life science meeting.
- Place of Presentation
  Osaka
- Year and Date
  2007-03-12
- Description
  「研究成果報告書概要(欧文)」より
- Data Source
  KAKENHI-PROJECT-18570136
[Presentation] 酸化ストレスに応答して誘導されるIKKγ/NEMOの分子間ジスルフィド結合2007
- Author(s)
  夏原芳里, 土谷佳弘, 浅野知一郎, 鎌田英明
- Organizer
  第30回日本分子生物学会・第80回日本生化学会合同大会
- Place of Presentation
  横浜
- Year and Date
  2007-12-14
- Description
  「研究成果報告書概要(和文)」より
- Data Source
  KAKENHI-PROJECT-18570136
[Presentation] 酸化ストレスに応答して誘導されるIKKy/NEMOの分子間ジスルフィド結合2007
- Author(s)
  夏原芳里、土谷佳弘、浅野知一郎、鎌田英明
- Organizer
  第30回日本分子生物学会・第80回日本生化学会合同大会
- Place of Presentation
  横浜
- Year and Date
  2007-12-08
- Data Source
  KAKENHI-PROJECT-19044026
[Presentation] TNFαによるIKK非依存的IκBαの分解制御に関する機能解析2007
- Author(s)
  土谷佳弘, 夏原芳里, 浅野知一郎, 鎌田英明
- Organizer
  第30回日本分子生物学会・第80回日本生化学会合同大会
- Place of Presentation
  横浜
- Year and Date
  2007-12-14
- Description
  「研究成果報告書概要(和文)」より
- Data Source
  KAKENHI-PROJECT-18570136
[Presentation] MAPキナーゼホスフアターゼ(MKPs)とPTENを介した細胞の生と死のレドツクス制御2007
- Author(s)
  鎌田英明
- Organizer
  レドックス生命科学研究会
- Place of Presentation
  大阪
- Year and Date
  2007-03-12
- Description
  「研究成果報告書概要(和文)」より
- Data Source
  KAKENHI-PROJECT-18570136
[Presentation] Molecular mechanism of failure in LKB1-AMPK・SIK-TORC2 pathway by high-fat diet.2007
- Author(s)
  Masayasu Yoneda, Haruya Ono, Hideayuki Sakoda, Yusuke Nakatsu, Kouryu Sak Kun Cyou, Ei Kaku, Makiko Egawa, Hideaki Kamata, Tomoichiro Asano
- Organizer
  Symposium of molecular diabetes.
- Place of Presentation
  Kobe
- Year and Date
  2007-12-14
- Description
  「研究成果報告書概要(欧文)」より
- Data Source
  KAKENHI-PROJECT-18570136
[Presentation] TNFαによるIKK非依存的IκBαの分解制御に関する機能解析2007
- Author(s)
  土谷佳弘、夏原方里、浅野知一郎、鎌田英明
- Organizer
  第30回日本分子生物学会・第80回日本生化学会合同大会
- Place of Presentation
  横浜
- Year and Date
  2007-12-08
- Data Source
  KAKENHI-PROJECT-19044026
[Presentation] Redox regulation of cell death and proliferation by coupling of MAP kinase phosphatase (MKP) and PTEN.2006
- Author(s)
  Hideaki Kamata. Yoshihiro Tsuchiy, Kaori Natsuhar, Hajime Hirata, Tomoichiro Asano
- Organizer
  Annual Meeting of Japanese Cancer Society
- Place of Presentation
  Yokohama
- Year and Date
  2006-09-29
- Description
  「研究成果報告書概要(欧文)」より
- Data Source
  KAKENHI-PROJECT-18570136
[Presentation] MAPキナーゼホスフアクーゼ(MKPs)とPTENの共役による細胞死と細胞増殖のレドツクス制御2006
- Author(s)
  鎌田英明土谷佳弘, 夏原芳里, 平田肇, 浅野知一郎
- Organizer
  日本癌学会
- Place of Presentation
  横浜
- Year and Date
  2006-09-29
- Description
  「研究成果報告書概要(和文)」より
- Data Source
  KAKENHI-PROJECT-18570136
[Presentation] IKKβの脱リン酸化反応における転写因子RelAの関与
- Author(s)
  土谷佳弘, 金本麻裕, 菅野雅元, 浅野知一郎, 鎌田英明
- Organizer
  日本生化学会合同大会
- Place of Presentation
  福岡
- Data Source
  KAKENHI-PROJECT-23370062
[Presentation] プロリン異性化酵素Pin1による新規AMPK 機能制御機構の解明
- Author(s)
  中津祐介，岩下未咲，松永泰花，福嶋俊明，迫田秀之，櫛山暁史，鎌田英明，内田隆史，高橋伸一郎，浅野知一郎
- Organizer
  第36回日本分子生物学会
- Place of Presentation
  神戸
- Data Source
  KAKENHI-PROJECT-24657092
[Presentation] IKKβの脱リン酸化反応における転写因子RelAの関与
- Author(s)
  土谷佳弘, 金本麻裕, 菅野雅元, 浅野知一郎, 鎌田英明
- Organizer
  第85回日本生化学会合同大会
- Place of Presentation
  福岡
- Data Source
  KAKENHI-PLANNED-20117012
[Presentation] TNFに応答したRIP1/RIP3複合体形成における活性酸素種(ROS)の関与と細胞の生と死の制御
- Author(s)
  金本麻裕, 土谷佳弘, 浅野知一郎, 鎌田英明
- Organizer
  第36回日本分子生物学会
- Place of Presentation
  神戸
- Data Source
  KAKENHI-PROJECT-24657092
[Presentation] Stress-induced NF-kB activation mediated by the nuclear IKK and cell death
- Author(s)
  13. 土谷佳弘, 金本麻裕, 菅野雅元, 浅野知一郎, 鎌田英明
- Organizer
  第35回日本分子生物学会
- Place of Presentation
  福岡
- Data Source
  KAKENHI-PLANNED-20117012
[Presentation] ストレス応答による核内IKKβを介したNF-κB活性化と細胞死
- Author(s)
  土谷佳弘, 金本麻裕, 浅野知一郎, 鎌田英明
- Organizer
  第86回日本生化学会合同大会
- Place of Presentation
  横浜
- Data Source
  KAKENHI-PLANNED-20117012
[Presentation] ストレス応答による核内IKKβを介したNF-κB活性化と細胞死
- Author(s)
  土谷佳弘, 金本麻裕, 浅野知一郎, 鎌田英明
- Organizer
  第86回日本生化学会合同大会
- Place of Presentation
  横浜
- Data Source
  KAKENHI-PROJECT-23370062
[Presentation] TNFに連関したシグナル系のレドックス制御と細胞死
- Author(s)
  鎌田英明
- Organizer
  第85回日本生化学会合同大会シンポジウム
- Place of Presentation
  福岡
- Invited
- Data Source
  KAKENHI-PROJECT-24657092
[Presentation] Nedd4-IRS2複合体の形成機構とこの複合体が前立腺がん細胞の過増殖に果たす役割
- Author(s)
  福嶋俊明，吉原英人，古田遥佳，伯野史彦，千田和広，佐伯泰，田中啓二，伊藤昭博，田稔，中津祐介，鎌田英明，高橋伸一郎，浅野知一郎
- Organizer
  第36回日本分子生物学会
- Place of Presentation
  神戸
- Data Source
  KAKENHI-PROJECT-24657092
[Presentation] TNFに連関したシグナル系のレドックス制御と細胞死
- Author(s)
  10. 鎌田英明
- Organizer
  第85回日本生化学会合同大会
- Place of Presentation
  福岡
- Invited
- Data Source
  KAKENHI-PLANNED-20117012
[Presentation] 腫瘍壊死因子(TNFα)に応答した細胞死とRIP1とRIP3の発現変化
- Author(s)
  12. 金本麻裕, 土谷佳弘, 浅野知一郎, 鎌田英明
- Organizer
  日本生化学会合同大会
- Place of Presentation
  福岡
- Data Source
  KAKENHI-PROJECT-23370062
[Presentation] 腫瘍壊死因子(TNF)に応答したネクロプトーシス誘導キナーゼRIP-3の細胞外分泌による細胞死の制御
- Author(s)
  金本麻裕, 土谷佳弘, 浅野知一郎, 鎌田英明
- Organizer
  第86回日本生化学会合同大会
- Place of Presentation
  横浜
- Data Source
  KAKENHI-PROJECT-24657092
[Presentation] 非アルコール性脂肪肝炎発症におけるLUBAC の形成の解析
- Author(s)
  松永泰花，中津祐介，福嶋俊明，大久保博史，迫田秀之，土谷佳弘，鎌田英明，徳永文稔，岩井一宏，浅野知一郎
- Organizer
  第36回日本分子生物学会
- Place of Presentation
  神戸
- Data Source
  KAKENHI-PROJECT-23370062
[Presentation] 転写活性非依存性のRelA によるIKKbの活性制御機構
- Author(s)
  土谷佳弘, 金本麻裕, 浅野知一郎, 鎌田英明
- Organizer
  第36回日本分子生物学会
- Place of Presentation
  神戸
- Data Source
  KAKENHI-PROJECT-23370062
[Presentation] 非アルコール性脂肪肝炎発症におけるLUBAC の形成の解析
- Author(s)
  松永泰花，中津祐介，福嶋俊明，大久保博史，迫田秀之，土谷佳弘，鎌田英明，徳永文稔，岩井一宏，浅野知一郎
- Organizer
  第36回日本分子生物学会
- Place of Presentation
  神戸
- Data Source
  KAKENHI-PLANNED-20117012
[Presentation] Stress-induced NF-kB activation mediated by the nuclear IKK and cell death
- Author(s)
  土谷佳弘, 金本麻裕, 菅野雅元, 浅野知一郎, 鎌田英明
- Organizer
  第35回日本分子生物学会
- Place of Presentation
  福岡
- Data Source
  KAKENHI-PROJECT-23370062
[Presentation] プロリン異性化酵素Pin1による新規AMPK 機能制御機構の解明
- Author(s)
  中津祐介，岩下未咲，松永泰花，福嶋俊明，迫田秀之，櫛山暁史，鎌田英明，内田隆史，高橋伸一郎，浅野知一郎
- Organizer
  第36回日本分子生物学会
- Place of Presentation
  神戸
- Data Source
  KAKENHI-PLANNED-20117012
[Presentation] TNFに連関したシグナル系のレドックス制御と細胞死
- Author(s)
  鎌田英明
- Organizer
  日本生化学会合同大会
- Place of Presentation
  福岡
- Invited
- Data Source
  KAKENHI-PROJECT-23370062
[Presentation] 腫瘍壊死因子(TNF)に応答したネクロプトーシス誘導キナーゼRIP-3の細胞外分泌による細胞死の制御
- Author(s)
  金本麻裕, 土谷佳弘, 浅野知一郎, 鎌田英明
- Organizer
  第86回日本生化学会合同大会
- Place of Presentation
  横浜
- Data Source
  KAKENHI-PROJECT-23370062
[Presentation] 転写活性非依存性のRelA によるIKKbの活性制御機構
- Author(s)
  土谷佳弘, 金本麻裕, 浅野知一郎, 鎌田英明
- Organizer
  第36回日本分子生物学会
- Place of Presentation
  神戸
- Data Source
  KAKENHI-PLANNED-20117012
[Presentation] 腫瘍壊死因子(TNFα)に応答した細胞死とRIP1とRIP3の発現変化
- Author(s)
  金本麻裕, 土谷佳弘, 浅野知一郎, 鎌田英明
- Organizer
  第85回日本生化学会合同大会
- Place of Presentation
  福岡
- Data Source
  KAKENHI-PROJECT-24657092
[Presentation] ストレス応答による核内IKKβを介したNF-κB活性化と細胞死
- Author(s)
  土谷佳弘, 金本麻裕, 浅野知一郎, 鎌田英明
- Organizer
  第86回日本生化学会合同大会
- Place of Presentation
  横浜
- Data Source
  KAKENHI-PROJECT-24657092
[Presentation] Stress-induced NF-kB activation mediated by the nuclear IKK and cell death
- Author(s)
  土谷佳弘, 金本麻裕, 菅野雅元, 浅野知一郎, 鎌田英明
- Organizer
  第35回日本分子生物学会
- Place of Presentation
  福岡
- Data Source
  KAKENHI-PROJECT-24657092
[Presentation] Nedd4-IRS2複合体の形成機構とこの複合体が前立腺がん細胞の過増殖に果たす役割
- Author(s)
  2. 福嶋俊明，吉原英人，古田遥佳，伯野史彦，千田和広，佐伯泰，田中啓二，伊藤昭博，田稔，中津祐介，鎌田英明，高橋伸一郎，浅野知一郎
- Organizer
  第36回日本分子生物学会
- Place of Presentation
  神戸
- Data Source
  KAKENHI-PROJECT-23370062
[Presentation] IKKβの脱リン酸化反応における転写因子RelAの関与
- Author(s)
  土谷佳弘, 金本麻裕, 菅野雅元, 浅野知一郎, 鎌田英明
- Organizer
  第85回日本生化学会合同大会ワークショップ
- Place of Presentation
  福岡
- Data Source
  KAKENHI-PROJECT-24657092
[Presentation] プロリン異性化酵素Pin1による新規AMPK 機能制御機構の解明
- Author(s)
  中津祐介，岩下未咲，松永泰花，福嶋俊明，迫田秀之，櫛山暁史，鎌田英明，内田隆史，高橋伸一郎，浅野知一郎
- Organizer
  第36回日本分子生物学会
- Place of Presentation
  神戸
- Data Source
  KAKENHI-PROJECT-23370062
[Presentation] 転写活性非依存性のRelA によるIKKbの活性制御機構
- Author(s)
  土谷佳弘, 金本麻裕, 浅野知一郎, 鎌田英明
- Organizer
  第36回日本分子生物学会
- Place of Presentation
  神戸
- Data Source
  KAKENHI-PROJECT-24657092
[Presentation] TNFに応答したRIP1/RIP3複合体形成における活性酸素種(ROS)の関与と細胞の生と死の制御
- Author(s)
  金本麻裕, 土谷佳弘, 浅野知一郎, 鎌田英明
- Organizer
  第36回日本分子生物学会
- Place of Presentation
  神戸
- Data Source
  KAKENHI-PROJECT-23370062
[Presentation] Nedd4-IRS2複合体の形成機構とこの複合体が前立腺がん細胞の過増殖に果たす役割
- Author(s)
  福嶋俊明，吉原英人，古田遥佳，伯野史彦，千田和広，佐伯泰，田中啓二，伊藤昭博，田稔，中津祐介，鎌田英明，高橋伸一郎，浅野知一郎
- Organizer
  第36回日本分子生物学会
- Place of Presentation
  神戸
- Data Source
  KAKENHI-PLANNED-20117012

1. HIRATA Hajime (40049052)

# of Collaborated Projects: 7 results

# of Collaborated Products: 3 results
2. YAGISAWA Hitoshi (40192380)

# of Collaborated Projects: 5 results

# of Collaborated Products: 0 results
3. ASANO Tomoichiro (70242063)

# of Collaborated Projects: 2 results

# of Collaborated Products: 72 results
4. NAKATSU Yusuke (20452584)

# of Collaborated Projects: 2 results

# of Collaborated Products: 41 results
5. AKAIKE Takaaki (20231798)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
6. SUMIMOTO Hideki (30179303)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
7. UCHIDA Koji (40203533)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
8. MATSUMOTO Akio (60437308)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
9. URANO Yasuteru (20292956)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
10. ARIMOTO Hirokazu (60262789)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
11. ITOH Ken (10323289)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
12. SHIMOKAWA Hiroaki (00235681)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
13. TSUTSUI Hiroyuki (70264017)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
14. UEHARA Takashi (00261321)

# of Collaborated Projects: 1 results

# of Collaborated Products: 2 results
15. NISHIDA Motohiro (90342641)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
16. YOEDA Masayasu (30508130)

# of Collaborated Projects: 1 results

# of Collaborated Products: 9 results
17. SAKODA Hideyuki (50376464)

# of Collaborated Projects: 1 results

# of Collaborated Products: 1 results
18. SOTOMARU Yusuke (90309352)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
19. HIRATA Masato (60136471)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
20. HIGUCHI Yoshiki (90183574)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
21. TSUCHIYA Yoshihiro (90611301)

# of Collaborated Projects: 1 results

# of Collaborated Products: 5 results
22. 野島博 (30156195)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
23. ONO Hiraku

# of Collaborated Projects: 0 results

# of Collaborated Products: 1 results
24. 福嶋俊明

# of Collaborated Projects: 0 results

# of Collaborated Products: 3 results
25. 山本雅之

# of Collaborated Projects: 0 results

# of Collaborated Products: 1 results
26. 松原昭郎

# of Collaborated Projects: 0 results

# of Collaborated Products: 1 results
27. 徳永文稔

# of Collaborated Projects: 0 results

# of Collaborated Products: 1 results
28. 西村英紀

# of Collaborated Projects: 0 results

# of Collaborated Products: 1 results

KAMATA Hideaki 鎌田 英明

Research Projects

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Co-Researchers

Molecular mechanisms of gene expression linked to chronic inflammation and hepatocellular carcinogenesisPrincipal Investigator

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計画的細胞死に共役した細胞内小胞輸送の改変と細胞外シグナルの生成Principal Investigator

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腫瘍壊死因子が産生する活性酸素によるシグナル制御と炎症と発がんPrincipal Investigator

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Crosstalk between citrate sycle and gene expression system and inflammation and cancerPrincipal Investigator

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Involvement of NF-kB regulation by nuclear IKKb in inflammation and cancerPrincipal Investigator

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Involvement of cellular stress-medicated NF-kB activation in inflammation and cancerPrincipal Investigator

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Cellular signaling systems regulated by oxidative stress and ROS-sensitive phosphatasesPrincipal Investigator

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腫瘍壊死因子によるユビキチンリガーゼItchを介したタンパク質分解と細胞応答Principal Investigator

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Redox regulation of inflammation and carcinogenesis mediated by NF-κB/IKKβ and dual-specificity phosphatasePrincipal Investigator

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Regulation of bioenergy by NF-kB/IKKb signaling and oxidative stress-related diseasesPrincipal Investigator

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細胞のガン化に連関した細胞内シグナル伝達系のレドックス制御機構Principal Investigator

KAMATA Hideaki 鎌田英明