TAKAHARA Masatoshi 高原政利

Researcher Number	10236341
External Links
Affiliation (based on the past Project Information) *help	2007 – 2008: Yamagata University, Faculty ofMedicine, Associate Professor 2003 – 2006: 山形大学, 医学部, 助教授 2002: 山形大学, 医学部, 講師 2001: 山形大学, 医学部, 助手
Review Section/Research Field	Principal Investigator Orthopaedic surgery Except Principal Investigator Orthopaedic surgery / Orthopaedic surgery / Plastic surgery
Keywords	Principal Investigator brachypodism / GDF5 / gene therapy / articular cartilage / non-digit bearing / digit / joint / 遺伝子治療 / 関節軟骨 / 非荷重 … More / 手指 / 関節 / 生体材料 / 再生医学 / 神経病学 / 筋 … More Except Principal Investigator 人工関節 / congenital differences / hand / sports / cell transplantation / mesenchymal stromal cell / children / elbow joint / regenerative medicine / articular cartilage / MRI診断 / 骨髄間葉細胞 / 軟骨再生 / スポーツ / 細胞移植 / 骨髄間葉系細胞 / 小児 / 肘関節 / 関節軟骨 / 再生医療 / Impaction bone grafting / Allograft bone / Loosening / Osteolysis / Biocompatibility / Total Hip Joint / 骨移植 / 骨形成 / 骨吸収 / 再造形 / メカニカルストレス / 圧詰骨移植 / 同種骨 / 弛み / 骨溶解 / 生体親和性 / 人工股関節 / Toll-like receptor / チタン顆粒 / 細胞性生体反応 / シグナル伝達 / 骨髄マクロファージ / 骨溶解現象 / nail matrix / regeneration / nail / 爪甲形成一源説 / BrdU / 腎被膜下移植 / 免疫不全マウス / ヒト爪移植 / key words / tartrate-resistant acid phosphatase(TRAP) / matrix metalloproteinase-9(MMP-9) / ossification / cartilage / apoptosis / tartrate-resistant acid phosphatase (TRAP) / matrrx metalloproteinase-9 (MMP-9) Less

The regenerative effect of autologous growth factors on nectotic bone.Principal Investigator
- Principal Investigator
  
  HASHIMOTO Junichi, 高原政利
- Project Period (FY)
  2008 – 2010
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Research Field
  
  Orthopaedic surgery
- Research Institution
  Yamagata University
Autologous culture expanded bone marrow stromal cell transplantation for capitellar osteochondritis dissecans
- Principal Investigator
  
  KATO Hiroyuki
- Project Period (FY)
  2006 – 2007
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Research Field
  
  Orthopaedic surgery
- Research Institution
  Shinshu University
Analysis on phagocytic activities of titanium particles by macrophages derived from rat bone marrow
- Principal Investigator
  
  TAKAGI Michiaki
- Project Period (FY)
  2005 – 2008
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Research Field
  
  Orthopaedic surgery
- Research Institution
  Yamagata University
遺伝性のある上肢先天異常の症例調査(関連遺伝子分析の国際共同研究の準備)
- Principal Investigator
  
  荻野利彦
- Project Period (FY)
  2003
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Research Field
  
  Orthopaedic surgery
- Research Institution
  Yamagata University
爪甲の再生に関する研究〜重度複合免疫不全マウス腹腔内への爪組織移植モデルを用いて
- Principal Investigator
  
  MURA Nariyuki
- Project Period (FY)
  2003 – 2004
- Research Category
  
  Grant-in-Aid for Exploratory Research
- Research Field
  
  Plastic surgery
- Research Institution
  Yamagata University
Study on joint development and regeneration of the digital joint for gene therapyPrincipal Investigator
- Principal Investigator
  
  TAKAHASHI Masatoshi
- Project Period (FY)
  2003 – 2004
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Research Field
  
  Orthopaedic surgery
- Research Institution
  Yamagata University
内軟骨性骨化における軟骨吸収のメカニズムの解明:破軟骨細胞についての研究
- Principal Investigator
  
  OGINO Toshiko
- Project Period (FY)
  2001 – 2002
- Research Category
  
  Grant-in-Aid for Exploratory Research
- Research Field
  
  Orthopaedic surgery
- Research Institution
  Yamagata University
遺伝性のある上肢先天異常の症例調査(関連遺伝子分析の国際共同研究の準備)
- Principal Investigator
  
  荻野利彦
- Project Period (FY)
  2001
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Research Field
  
  Orthopaedic surgery
- Research Institution
  Yamagata University
Analysis of bone remodeling of impacted morselized chipped bone and its biological background for restoration of failed total hip arthroplasty with osteolysis.
- Principal Investigator
  
  TAKAGI Michiaki
- Project Period (FY)
  2000 – 2003
- Research Category
  
  Grant-in-Aid for Scientific Research (B)
- Research Field
  
  Orthopaedic surgery
- Research Institution
  Yamagata University

All 2010 2009 2008 2004 2003 Other

All Journal Article Presentation

[Journal Article] Effect of gelatin hydrogel incorporating fibroblast growth factor 2 on human meniscal cells in an organ culture model2009
- Author(s)
  Narita A, Takahara M, Ogino T, Fukushima S, Kimura Y, Tabata Y
- Journal Title
  
  The Knee 16
  
  Pages: 285-289
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-20591735
[Journal Article] Absence of biglycan accelerates the degenerative process in mouse intervertebral disc2009
- Author(s)
  Furukawa T, Ito K, Nuka S, Hashimoto J, Takei H, Takahara M, Ogino T
- Journal Title
  
  Spine 34
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-20591735
[Journal Article] ゼラチンハイドロゲルと線維芽細胞増殖因子を用いた半月板修復2009
- Author(s)
  成田淳,高原政利,佐藤大祐,荻野利彦,福島重宣,田畑泰彦
- Journal Title
  
  日本整形外科スポーツ医学会雑誌 29
  
  Pages: 119-127
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-20591735
[Journal Article] Classification, treatment, and outcome of osteochondritis dissecans of the humeral capitellum2008
- Author(s)
  Masatoshi Takahara
- Journal Title
  
  Journal Bone and Joint Surgery 90
  
  Pages: 47-62
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-20591735
[Journal Article] Developmental failure of phalanges in the absence of growth/differentiation factor 52004
- Author(s)
  Masatoshi Takahara, et al.
- Journal Title
  
  Bone 35
  
  Pages: 1069-1076
- Data Source
  KAKENHI-PROJECT-15591562
[Journal Article] Matrix metalloproteinase-9 expression, tartrate-resistant acid phosphatase activity, and DNA fragmentation in vascular and cellular invasion into cartilage pr eceding primary endochondral ossification in long bones2004
- Author(s)
  Masatoshi Takahara, et al.
- Journal Title
  
  Journal of Orthopaedic Research 22 22
  
  Pages: 1050-1057
- Description
  「研究成果報告書概要(和文)」より
- Data Source
  KAKENHI-PROJECT-15591562
[Journal Article] Developmental fai lure of phalanges in the absence of growth/differentiation factor 52004
- Author(s)
  Masatoshi Takahara, et al.
- Journal Title
  
  Bone 35
  
  Pages: 1069-1076
- Description
  「研究成果報告書概要(和文)」より
- Data Source
  KAKENHI-PROJECT-15591562
[Journal Article] Matrix metalloproteinase-9 expression, tartrate-resistant acid phosphatase activity, and DNA fragmentation in vascular and cellular invasion into cartilage preceding primary endochondral ossification in long bones2004
- Author(s)
  Masatoshi Takahara, et al.
- Journal Title
  
  Journal of Orthopaedic Research 22 22
  
  Pages: 1050-1057
- Data Source
  KAKENHI-PROJECT-15591562
[Journal Article] Developmental failure of phalanges in the absence of growth/differentiation factor 5.2004
- Author(s)
  Takahara M, et al.
- Journal Title
  
  Bone 35
  
  Pages: 1069-1076
- Description
  「研究成果報告書概要(欧文)」より
- Data Source
  KAKENHI-PROJECT-15591562
[Journal Article] Matrix metallopreteinase-9 expression, tartrate-resistant acid phosphatase activity, and DNA fragmentation in vascular and cellular invasion into cartilage preceding primary endochondral ossification in long bones.2004
- Author(s)
  Takahara M, et al.
- Journal Title
  
  J Orthop Res 22
  
  Pages: 1050-1057
- Description
  「研究成果報告書概要(欧文)」より
- Data Source
  KAKENHI-PROJECT-15591562
[Journal Article] マウス指発生におけるGDF5の役割.2003
- Author(s)
  原田幹生, 高原政利他
- Journal Title
  
  日本整形外科学会雑誌 77巻
  
  Pages: 1109-1109
- Description
  「研究成果報告書概要(和文)」より
- Data Source
  KAKENHI-PROJECT-15591562
[Journal Article] 非荷重関節における骨軟骨欠損の実験的研究
- Author(s)
  原田幹生, 高原政利他
- Journal Title
  
  日本肘関節学会雑誌 (印刷中)
- Description
  「研究成果報告書概要(和文)」より
- Data Source
  KAKENHI-PROJECT-15591562
[Presentation] The effect of platelet- rich plasma on the healing of intrasynovial flexor tendons : in vivo study2010
- Author(s)
  Sato D, Takahara M, Narita A, Yamakawa J, Hashimoto J, Ogino T
- Organizer
  7th Combined Meeting of the Orthopaedic Research Society
- Place of Presentation
  Kyoto/Japan
- Data Source
  KAKENHI-PROJECT-20591735
[Presentation] The Effect of Platelet-rich Plasma on the Healing of Intrasynovial Flexor Tendons : In Vivo Study.2010
- Author(s)
  Sato D, Takahara M, Narita A, Yamakawa J, Hashimoto J, Ogino T
- Organizer
  11th Triennial Congress of the International Foderation of Societies for Surgery of Hand
- Place of Presentation
  Seoul/Korea
- Data Source
  KAKENHI-PROJECT-20591735
[Presentation] 屈筋腱損傷に対するPRPの影響:器官培養での検討2009
- Author(s)
  佐藤大祐, 高原政利, 成田淳, 山川淳一, 伊藤和生, 橋本淳一, 荻野利彦
- Organizer
  第8回日本再生医療学会
- Place of Presentation
  東京
- Data Source
  KAKENHI-PROJECT-20591735
[Presentation] Effect of gelatin hydrogel incorporating fibroblast growth factor 2 on human meniscal cells in an organ culture model2009
- Author(s)
  Narita A, Takahara M, Sato D, Ogino T, Fukushima S, Kimura Y, Tabata Y
- Organizer
  The 55th Annual Meeting of the Orthopaedic Research Society
- Place of Presentation
  Las Vegas/USA
- Data Source
  KAKENHI-PROJECT-20591735
[Presentation] 肘関節鏡2009
- Author(s)
  高原政利
- Organizer
  第15回日本手の外科学会教育研究講演
- Place of Presentation
  東京
- Year and Date
  2009-04-18
- Data Source
  KAKENHI-PROJECT-20591735
[Presentation] Outcome of osteochondritis dissecans of the humeral capitellum2008
- Author(s)
  Masatoshi Takahara
- Organizer
  21st Congress of the European Society for Surgery of the Shoulder and the Elbow
- Place of Presentation
  Brugge
- Data Source
  KAKENHI-PROJECT-20591735

1. OGINO Toshiko (60109436)

# of Collaborated Projects: 7 results

# of Collaborated Products: 0 results
2. TAKAGI Michiaki (40241707)

# of Collaborated Projects: 7 results

# of Collaborated Products: 0 results
3. TAKEI Hiroshi (40292437)

# of Collaborated Projects: 5 results

# of Collaborated Products: 0 results
4. TSUCHIDA Hiroyuki (40250922)

# of Collaborated Projects: 3 results

# of Collaborated Products: 0 results
5. KOBAYASHI Shinji (60312740)

# of Collaborated Projects: 3 results

# of Collaborated Products: 0 results
6. MURA Nariyuki (00312728)

# of Collaborated Projects: 2 results

# of Collaborated Products: 0 results
7. KIKUCHI Noriaki (90361261)

# of Collaborated Projects: 2 results

# of Collaborated Products: 0 results
8. GOTO Kaoru (30234975)

# of Collaborated Projects: 2 results

# of Collaborated Products: 0 results
9. HASHIMOTO Junichi (10359565)

# of Collaborated Projects: 2 results

# of Collaborated Products: 4 results
10. WATANABE Tadayoshi (90422170)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
11. TABATA Yasuhiko (50211371)

# of Collaborated Projects: 1 results

# of Collaborated Products: 3 results
12. NARITA Atsushi (60400579)

# of Collaborated Projects: 1 results

# of Collaborated Products: 6 results
13. KATO Hiroyuki (40204490)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
14. WAKITANI Shigeyuki (70243243)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
15. OHGUSHI Hajime (80213669)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
16. KADOYA Masumi (40115225)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
17. YOSHIMURA Yasuo (10303439)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
18. 柏英雄 (80204379)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
19. 村垣泰光 (40190904)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
20. 野地澄晴 (40156211)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
21. 井田英雄 (40184600)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
22. 村上成道 (50334892)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results

TAKAHARA Masatoshi 高原 政利

Research Projects

Research Products

Co-Researchers

The regenerative effect of autologous growth factors on nectotic bone.Principal Investigator

Principal Investigator

Project Period (FY)

Research Category

Research Field

Research Institution

Autologous culture expanded bone marrow stromal cell transplantation for capitellar osteochondritis dissecans

Principal Investigator

Project Period (FY)

Research Category

Research Field

Research Institution

Analysis on phagocytic activities of titanium particles by macrophages derived from rat bone marrow

Principal Investigator

Project Period (FY)

Research Category

Research Field

Research Institution

遺伝性のある上肢先天異常の症例調査(関連遺伝子分析の国際共同研究の準備)

Principal Investigator

Project Period (FY)

Research Category

Research Field

Research Institution

爪甲の再生に関する研究〜重度複合免疫不全マウス腹腔内への爪組織移植モデルを用いて

Principal Investigator

Project Period (FY)

Research Category

Research Field

Research Institution

Study on joint development and regeneration of the digital joint for gene therapyPrincipal Investigator

Principal Investigator

Project Period (FY)

Research Category

Research Field

Research Institution

内軟骨性骨化における軟骨吸収のメカニズムの解明:破軟骨細胞についての研究

Principal Investigator

Project Period (FY)

Research Category

Research Field

Research Institution

遺伝性のある上肢先天異常の症例調査(関連遺伝子分析の国際共同研究の準備)

Principal Investigator

Project Period (FY)

Research Category

Research Field

Research Institution

Analysis of bone remodeling of impacted morselized chipped bone and its biological background for restoration of failed total hip arthroplasty with osteolysis.

Principal Investigator

Project Period (FY)

Research Category

Research Field

Research Institution

[Journal Article] Effect of gelatin hydrogel incorporating fibroblast growth factor 2 on human meniscal cells in an organ culture model2009

Author(s)

Journal Title

Data Source

[Journal Article] Absence of biglycan accelerates the degenerative process in mouse intervertebral disc2009

Author(s)

Journal Title

Data Source

[Journal Article] ゼラチンハイドロゲルと線維芽細胞増殖因子を用いた半月板修復2009

Author(s)

Journal Title

Data Source

[Journal Article] Classification, treatment, and outcome of osteochondritis dissecans of the humeral capitellum2008

Author(s)

Journal Title

Data Source

[Journal Article] Developmental failure of phalanges in the absence of growth/differentiation factor 52004

Author(s)

Journal Title

Data Source

[Journal Article] Matrix metalloproteinase-9 expression, tartrate-resistant acid phosphatase activity, and DNA fragmentation in vascular and cellular invasion into cartilage pr eceding primary endochondral ossification in long bones2004

Author(s)

TAKAHARA Masatoshi 高原政利