SUGIYAMA Kazuo 杉山和夫

Researcher Number	10242520
External Links
Affiliation (based on the past Project Information) *help	2013: 慶應義塾大学, 医学部, 特任准教授 2012: 慶應義塾大学, 医学部, 准教授 2011: 慶應義塾大学, 医学部, 特任准教授 2007 – 2008: Keio University, 医学部, 准教授 2006: Saitama Medical University, 医学部, 講師 … More 2001: National Cancer Center Research Institure, Virology Division, Stuff, 研究所・ウイルス部, 研究員 2000: 国立がんセンター研究所, ウイルス部, 研究員 1998: 国立がんセンター, 研究所ウイルス部, 研究員 1997 – 1998: 国立がんセンター, 研究所・ウイルス部, 研究員 Less
Review Section/Research Field	Principal Investigator Virology / Virology
Keywords	Principal Investigator C型肝炎ウイルス / 感染性クローン / long RT-PCR / Hepatitis C virus / レプリコン / Huh-7 cell / MT-2C cell / Replicon / レトロウイルスベクター / MT2-C細胞 … More / Huh-7細胞 / MT-2C細胞 / cell culture / infectious clone / Hepatitis Cvirus / long RTPCR / long RT PCR / 培養細胞 / metabolome / hepatocellular carcinoma / 脂質代謝 / 代謝 / ペントースリン酸系 / 持続感染 / Ｃ型肝炎ウイルス / 脂肪滴 / メタボローム / Nrf2 / 脂肪酸 / コレステロール / ペントースリン酸経路 / ウイルス複製 / 欠損ウイルス / 複製 / 病理学 / ウイルス学 Less

Metabolic Analysis of the Cultured Hepatic Cell Persistently Infected with Hepatitis C VirusPrincipal Investigator
- Principal Investigator
  
  SUGIYAMA Kazuo
- Project Period (FY)
  2011 – 2013
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Research Field
  
  Virology
- Research Institution
  Keio University
Establishment of the cell line supporting heptitis C virus replication efficiently and generation of an infectious clone of genotype 1bPrincipal Investigator
- Principal Investigator
  
  SUGIYAMA Kazuo
- Project Period (FY)
  2006 – 2008
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Research Field
  
  Virology
- Research Institution
  Keio University
  Saitama Medical University
Development of Replication System using A Hepatitis C Virus Infectious Clone and its ApplicationPrincipal Investigator
- Principal Investigator
  
  SUGIYAMA Kazuo
- Project Period (FY)
  2000 – 2001
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Research Field
  
  Virology
- Research Institution
  National Cancer Center Research Institute(C)(2)
Cell Cuiture System Supporting Hepatitis C Virus Replication by Using Infections RNAPrincipal Investigator
- Principal Investigator
  
  SUGIYAMA Kazuo
- Project Period (FY)
  1997 – 1998
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Research Field
  
  Virology
- Research Institution
  National Cancer Center Research Institute

All 2014 2013 2012 2011 2009 2008 2007 2006

All Journal Article Presentation Book

[Book] がん生物学イラストレイテッド、腫瘍ウイルス(肝炎ウイルス)2011
- Author(s)
  宇治野真之, 杉山和夫, 下遠野邦忠
- Total Pages
  10
- Publisher
  羊土社
- Data Source
  KAKENHI-PROJECT-23590551
[Book] がん生物学イラストレイティド, 腫瘍ウイルス(肝炎ウイルス)2011
- Author(s)
  杉山和夫, (渋谷正史,湯浅保仁編)
- Publisher
  羊土社
- Data Source
  KAKENHI-PROJECT-23590551
[Book] Cancer Treatment Navigator(家族性腫瘍)(中川和彦編)2008
- Author(s)
  杉山和夫
- Publisher
  メディカルレビュー社
- Data Source
  KAKENHI-PROJECT-18590454
[Book] Cancer Treatment Navigator (中川和彦編)2008
- Author(s)
  杉山和夫
- Publisher
  メディカルレビュー社
- Data Source
  KAKENHI-PROJECT-18590454
[Journal Article] Prominent steatosis with hypermetabolism of the cell line permissive for years of infection with hepatitis C virus2014
- Author(s)
  Sugiyama, K. Ebinuma, H. Nakamoto, N. Sakasegawa, N. Murakami, Y. Chu, P. S. Usui, S. Ishibashi, Y. Wakayama, Y. Taniki, N. Murata, H. Saito, Y. Fukasawa, M. Saito, K. Yamagishi, Y. Wakita, T. Takaku, H. Hibi, T. Saito, H. Kanai, T.
- Journal Title
  
  PLoS ONE
  
  Volume: 9 Issue: 4 Pages: 849-854
- DOI
  10.1371/journal.pone.0094460
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-23590551, KAKENHI-PROJECT-24590557, KAKENHI-PROJECT-24590993
[Journal Article] Free cholesterol accumulation in hepatic stellate cells: Mechanism of liver fibrosis aggravation in nonalcoholic steatohepatitis in mice2014
- Author(s)
  Tomita, K. Teratani, T. Suzuki, T. Shimizu, M. Sato, H. Narimatsu, K. Okada, Y. Kurihara, C. Irie, R. Yokoyama, H. Shimamura, K. Usui, S. Ebinuma, H. Saito, H. Watanabe, C. Komoto, S. Kawaguchi, A. Nagao, S. Sugiyama, K. Hokari, R. Kanai, T. Miura, S. Hibi, T.
- Journal Title
  
  Hepatology
  
  Volume: 59 Issue: 1 Pages: 154-169
- DOI
  10.1002/hep.26604
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-23590551, KAKENHI-PROJECT-23591001, KAKENHI-PROJECT-24249046, KAKENHI-PROJECT-24390190, KAKENHI-PROJECT-24590993, KAKENHI-PROJECT-24790719
[Journal Article] C-C motif chemokine receptor 9 positive macrophages activate hepatic stellate cells and promote liver fibrosis in mice.2013
- Author(s)
  Chu PS, Nakamoto N, Ebinuma H, Usui S, Saeki K, Matsumoto A, Mikami Y, Sugiyama K, Tomita K, Kanai T, Saito H, Hibi T.
- Journal Title
  
  Hepatology
  
  Volume: 58 Issue: 1 Pages: 337-350
- DOI
  10.1002/hep.26351
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-12J05920, KAKENHI-PROJECT-23590551, KAKENHI-PROJECT-23591001, KAKENHI-PROJECT-24249046
[Journal Article] Suppressive Effect of the Histone Deacetylase Inhibitor, Suberoylanilide Hydroxamic Acid (SAHA), on Hepatitis C Virus Replication via Epigenetic Changes in Host Cells2013
- Author(s)
  Sato, A., Saito, Y., Sugiyama, K., Sakasegawa, N., Muramatsu, T., Fukuda, S., Yoneya, M., Kimura, M., Ebinuma, H., Hibi, T., Saito, H
- Journal Title
  
  J Cell Biochem
  
  Volume: 印刷中 Issue: 9 Pages: 1987-1996
- DOI
  10.1002/jcb.24541
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-23590551, KAKENHI-PROJECT-23680090, KAKENHI-PROJECT-24590993, KAKENHI-PROJECT-25293110
[Journal Article] Hepatitis C Virus Infection Induces Inflammatory Cytokines and Chemokines Mediated by the Cross Talk between Hepatocytes and Stellate Cells.2013
- Author(s)
  Nishitsuji H, Funami K, Shimizu Y, Ujino S, Sugiyama K, Seya T, Takaku H, Shimotohno K.
- Journal Title
  
  J. Viol
  
  Volume: 87 Issue: 14 Pages: 8169-8178
- DOI
  10.1128/jvi.00974-13
- Peer Reviewed
- Data Source
  KAKENHI-PLANNED-22114004, KAKENHI-PLANNED-22114008, KAKENHI-PROJECT-22249012, KAKENHI-PROJECT-23390120, KAKENHI-PROJECT-23590551, KAKENHI-PROJECT-24590993, KAKENHI-PROJECT-24659214
[Journal Article] A high-cholesterol diet exacerbates liver fibrosis in mice via accumulation of free cholesterol in hepatic stellate cells2012
- Author(s)
  Teratani T, Tomita K, Suzuki T, Oshikawa T, Yokoyama H, Shimamura K, Tominaga S, Hiroi S, Irie R, Okada Y, Kurihara C, Ebinuma H, Saito H, Hokari R, Sugiyama K, Kanai T, Miura S, Hibi T
- Journal Title
  
  Gastroenterology
  
  Volume: 142 Issue: 1 Pages: 152-164
- DOI
  10.1053/j.gastro.2011.09.049
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-23590551, KAKENHI-PROJECT-23591001
[Journal Article] The interaction between human initiation factor eIF3 subunit c and heat-shock protein 90: a necessary factor for translation mediated by the hepatitis C virus internal ribosome entry site.2012
- Author(s)
  Ujino S, Nishitsuji H, Sugiyama R, Suzuki H, Hishiki T, Sugiyama K, Shimotohno K, Takaku H
- Journal Title
  
  Virus Res.
  
  Volume: 163 Pages: 390-395
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-23590551
[Journal Article] p53/p66Shc-mediated signaling contributes to the progression of non-alcoholic steatohepatitis in humans and mice.2012
- Author(s)
  Tomita K, Teratani T, Shimamura K, Nishiyama N, Mataki R, Irie T, Minamino Y, Okada C, Kurihara H, Sugiyama K, et al
- Journal Title
  
  J Hepatol
  
  Volume: 57 Issue: 4 Pages: 837-843
- DOI
  10.1016/j.jhep.2012.05.013
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-23590551, KAKENHI-PROJECT-23591001, KAKENHI-PROJECT-24790719
[Journal Article] Development of monoclonal antibodies to human microsomal epoxide hydrolase and analysis of "preneoplastic antigen"-like molecules.2012
- Author(s)
  Dua H, Yoshimura K, Kobayashi N, Sugiyama K, Sawada JI, Saito Y, Morisseau C, Hammock BD, Akatsuka T
- Journal Title
  
  Toxicol. Appl. Pharmacol
  
  Volume: 260 Pages: 17-26
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-23590551
[Journal Article] Development of monoclonal antibodies to human microsomal epoxide hydrolase and analysis of "preneoplastic antigen"-like molecules.2012
- Author(s)
  Duan H, Yoshimura K, Kobayashi N, Sugiyama K, Sawada JI, Saito Y, Morisseau C, Hammock BD, Akatsuka T
- Journal Title
  
  Toxicol.
  
  Volume: 260 Issue: 1 Pages: 17-26
- DOI
  10.1016/j.taap.2012.01.023
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-23590551
[Journal Article] A high-cholesterol diet exacerbates liver fibrosis in mice via accumulation of free cholesterol in hepatic stellate cells.2012
- Author(s)
  Teratani T, Tomita K, Suzuki T, Oshikawa T, Yokoyama H, Shimamura K, Tominaga S, Hiroi S, Irie R, Okada Y, Kurihara C, Ebinuma H, Saito H, Hokari R, Sugiyama K, Kanai T, Miura S, Hibi T.
- Journal Title
  
  Gastroenterology
  
  Volume: 142
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-23590551
[Journal Article] Lipoprotein component associated with hepatitis C virus is essential for virus infectivity.2011
- Author(s)
  Shimizu Y, Hishiki T, Ujino S, Sugiyama K, Funami K, Shimotohno K.
- Journal Title
  
  Current Opinion in Virology
  
  Volume: 1 Pages: 19-26
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-23590551
[Journal Article] C型肝炎ウイルスの増幅機構2009
- Author(s)
  日紫喜隆行、杉山和夫
- Journal Title
  
  細胞 vol.41(6)
  
  Pages: 8-11
- Data Source
  KAKENHI-PROJECT-18590454
[Journal Article] Genetic Analysis of Hepatitis C Virus with Defective Genome and Its Infectivity in Vitro2009
- Author(s)
  Sugiyama K, Suzuki K, et.al.
- Journal Title
  
  Jvirol(Apr 15 (electric version))
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-18590454
[Journal Article] Genetic Analysis of Heptitis C Virus with Defective Genome and Its Infectivity in Vitro2009
- Author(s)
  Sugiyama, K., et al
- Journal Title
  
  V. Virology 83(電子版)
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-18590454
[Presentation] メタボローム・トランスクリプトーム統合的解析によるＣ型肝炎肝脂肪蓄積の機構解明2013
- Author(s)
  杉山和夫
- Organizer
  第17回日本肝臓学会大会
- Place of Presentation
  東京
- Data Source
  KAKENHI-PROJECT-23590551
[Presentation] Nrf2/sMaf転写因子複合体はHCVによる肝細胞脂肪蓄積に関与する2013
- Author(s)
  杉山和夫、海老沼浩利、酒瀬川典子、齋藤義正、金井隆典、日比紀文、齋藤英胤
- Organizer
  第72回日本癌学会総会
- Place of Presentation
  横浜
- Data Source
  KAKENHI-PROJECT-23590551
[Presentation] HCV持続感染細胞における転写因子Nrf2に制御される遺伝子群の発現解析2013
- Author(s)
  酒瀬川典子、杉山和夫、海老沼浩利、中本伸宏、村上優子、齋藤英胤、金井隆典
- Organizer
  第61回日本ウイルス学会
- Place of Presentation
  神戸
- Data Source
  KAKENHI-PROJECT-23590551
[Presentation] メタボローム・トランスクリプトーム統合的解析によるC型肝炎肝脂肪蓄積の機構解明2013
- Author(s)
  杉山和夫、齋藤英胤,日比紀文
- Organizer
  第16回日本肝臓学会大会(JDDW 2013)
- Place of Presentation
  東京
- Data Source
  KAKENHI-PROJECT-23590551
[Presentation] Epigenetics作用薬を用いたC型肝炎ウイルスの制御　ヒストン脱アセチル化阻害薬の有用性2013
- Author(s)
  齋藤英胤、齋藤義正、杉山和夫
- Organizer
  第49回日本肝臓学会総会
- Place of Presentation
  東京
- Data Source
  KAKENHI-PROJECT-23590551
[Presentation] Usefulness of a long-term (over 2 years) cultured cell clone persistently and productively infected with chimeric HCV2012
- Author(s)
  Sugiyama, K, Saito H, Ebinuma H, Sakasegawa N, Murakami Y, Nakamoto N, Usui S, Ishibashi Y, Chu P, Wakayama Y, Saito Y, Kanai T, Hibi T
- Organizer
  The 63rd annual meeting of the American association for the study of liver diseases
- Place of Presentation
  Boston USA
- Data Source
  KAKENHI-PROJECT-23590551
[Presentation] 新たなHCV研究ツールとしてのHCV持続感染培養肝細胞およびその治癒細胞の樹立2012
- Author(s)
  杉山和夫, 齋藤英胤, 酒瀬川典子, 村上優子, 海老沼浩利, 中本伸宏, 梅田瑠美子, 碓井真吾, 石橋由佳, 楮柏松, 若山遊子, 齋藤義正, 日比紀文
- Organizer
  第４８回日本肝臓学会総会
- Place of Presentation
  金沢
- Data Source
  KAKENHI-PROJECT-23590551
[Presentation] C型肝炎ウイルス持続感染における肝発癌と免疫異常：高発癌リスク因子を中心とした検討2012
- Author(s)
  楮柏松, 海老沼浩利, 中本伸宏, 碓井真吾, 梅田瑠美子, 石橋由佳, 若山遊子, 菊池真大, 山岸由幸, 杉山和夫, 金井隆典, 齋藤英胤, 日比紀文
- Organizer
  第４８回日本肝臓学会総会
- Place of Presentation
  金沢
- Data Source
  KAKENHI-PROJECT-23590551
[Presentation] 新たなHCV研究ツールとしてのHCV持続感染培養肝細胞およびその治癒細胞の樹立2012
- Author(s)
  杉山和夫、齋藤英胤、酒瀬川典子、村上優子、海老沼浩利、中本伸宏、梅田瑠美子、碓井真吾、石橋由佳、ちょ柏松、若山遊子、齋藤義正、日比紀文
- Organizer
  第48回日本肝臓学会総会
- Place of Presentation
  金沢(ワークショップ)
- Data Source
  KAKENHI-PROJECT-23590551
[Presentation] 長期間の持続感染培養肝細胞におけるHCVゲノムの自然発生的遺伝子変異の解析2012
- Author(s)
  酒瀬川典子, 杉山和夫, 齋藤英胤, 海老沼浩利, 村上優子, 中本伸宏, 金井隆典, 日比紀文
- Organizer
  第６０回日本ウイルス学会学術集会
- Place of Presentation
  大阪
- Data Source
  KAKENHI-PROJECT-23590551
[Presentation] New Insights on Hepatic Inflammatory Pseudotumor by Gd-EOB-DTPA MR Imaging2012
- Author(s)
  Usui S, Chu P, Wakayama Y, Ishibashi Y, Nakamoto N, Yamagishi Y, Masugi Y, Ebinuma H, Sugiyama K, Tanimoto A, Kanai T, Saito H, Hibi T
- Organizer
  ACG 2012 Annual Scientific Meeting
- Place of Presentation
  Las Vegas, USA
- Data Source
  KAKENHI-PROJECT-23590551
[Presentation] C型肝炎ウイルス(HCV)複製制御に係わる宿主因子Hsp70の機能解析2012
- Author(s)
  小倉大直, 君塚圭亮, 杉山隆一, 日紫喜隆行, 下遠野邦忠, 杉山和夫, 高久洋
- Organizer
  第６０回日本ウイルス学会学術集会
- Place of Presentation
  大阪
- Data Source
  KAKENHI-PROJECT-23590551
[Presentation] ヒストン脱アセチル化酵素阻害剤suberoylanilide hydroxamic acid (SAHA)によるC型肝炎ウイルス(HCV)の増殖抑制効果2012
- Author(s)
  佐藤郁美, 齋藤義正, 永見早耶花, 酒瀬川典子, 福田真也, 木村真規, 杉山和夫, 海老沼浩利, 齋藤英胤
- Organizer
  第４８回日本肝臓学会総会
- Place of Presentation
  金沢
- Data Source
  KAKENHI-PROJECT-23590551
[Presentation] コレステロール多量摂取は、肝星細胞の遊離コレステロール蓄積を介して、肝臓繊維化進展を引き起こす2012
- Author(s)
  冨田謙吾, 寺谷俊昭, 鈴木貴博, 横山裕一, 岡田義清, 栗原千枝, 海老沼浩利, 齋藤英胤, 渡辺知佳子, 高本俊介, 穂刈量太, 川口淳, 永尾重昭, 杉山和夫, 金井隆典, 日比紀文, 三浦総一郎
- Organizer
  第４８回日本肝臓学会総会
- Place of Presentation
  金沢
- Data Source
  KAKENHI-PROJECT-23590551
[Presentation] 当院における免疫抑制剤投与中のHBV感染の現状2012
- Author(s)
  碓井真吾, 海老沼浩利, 若山遊子, 楮柏松, 石橋由佳, 中本伸宏, 山岸由幸, 杉山和夫, 金井隆典, 齋藤英胤, 日比紀文
- Organizer
  第４８回日本肝臓学会総会
- Place of Presentation
  金沢
- Data Source
  KAKENHI-PROJECT-23590551
[Presentation] HCV研究私の研究とSerendipity、C型肝炎ウイルス持続感染培養肝細胞の樹立と応用2012
- Author(s)
  杉山和夫、齋藤英胤,日比紀文
- Organizer
  第39回日本肝臓学会東部会
- Place of Presentation
  東京(シンポジウム)
- Data Source
  KAKENHI-PROJECT-23590551
[Presentation] Peginterferon (PEG)/ Rivabirin (RBV)併用療法の治療成績からみた高齢者とりわけ高齢女性にたいする今後の治療展望2012
- Author(s)
  海老沼浩利, 齋藤英胤, 中本伸宏, 山岸由幸, 碓井真吾, 梅田瑠美子, 楮柏松, 石橋由佳, 若山遊子, 杉山和夫, 金井隆典, 日比紀文
- Organizer
  第４８回日本肝臓学会総会
- Place of Presentation
  金沢
- Data Source
  KAKENHI-PROJECT-23590551
[Presentation] １ｂ型HCVレプリコン複製細胞内のレプリコンRNAを効率よく感染性粒子としてtranspackagingする方法2012
- Author(s)
  村上優子, 杉山和夫, 齋藤英胤, 海老沼浩利, 中本伸宏, 酒瀬川典子, 斉藤聡, 金井隆典, 日比紀文, 高久洋
- Organizer
  第６０回日本ウイルス学会学術集会
- Place of Presentation
  大阪
- Data Source
  KAKENHI-PROJECT-23590551
[Presentation] Usefulness of A Long-term (Over 2 years) Cultured Cell Clone Persistently and Productively Infected with HCV2012
- Author(s)
  Sugiyama K, Saito H, Sakasegawa N, Murakami Y, Ebinuma H, Nakamoto N, Usui S, Ishibashi Y, Chu P, Wakayama Y, Saito Y, Kanai T, Hibi T
- Organizer
  The 63rd Annual Meeting of the American Association for the Study of Liver Diseases
- Place of Presentation
  Boston, USA
- Data Source
  KAKENHI-PROJECT-23590551
[Presentation] Recruited CCR9+ macrophages promote murine liver fibrosis through induction of TGF-β in hepatic stellate cells.2012
- Author(s)
  Chu P, Nakamoto N, Ebinuma H, Usui S, Sugiyama K, Kanai T, Saito H, Hibi T
- Organizer
  The 63rd annual meeting of the American association for the study of liver diseases
- Place of Presentation
  Boston USA
- Data Source
  KAKENHI-PROJECT-23590551
[Presentation] キメラHCV(1b/2a)持続感染細胞のメタボローム解析(Metabolome analysis of the cultured hepatocytes persistently infected with Chimeric HCV (1b/2a)2011
- Author(s)
  杉山和夫、齋藤英胤、海老沼浩利、高久洋、日比紀文
- Organizer
  第70回日本癌学会総会
- Place of Presentation
  名古屋
- Data Source
  KAKENHI-PROJECT-23590551
[Presentation] Metabolome analysis of the cultured hepatocytes persistently infected with Chimeric HCV (1b/2a).2011
- Author(s)
  Sugiyama, K. , Saito, H., Ebinuma, H., Takaku, H., Hibi, T.
- Organizer
  70th Annual Meeting of the Japanese Cancer Association.
- Place of Presentation
  名古屋国際会議場(愛知県）
- Data Source
  KAKENHI-PROJECT-23590551
[Presentation] Infectious hepatitis C virus bearing genotype-1b subgenomic replicon by trans-encapsidation with the structural regions of genotype 1b.2011
- Author(s)
  Sugiyama, K., Murakami, Y., Hishiki, T., Shimizu, Y., Funami, K., Ujino, S., Saito, H., Saito, S., Kato, N., Hibi, T., Takaku, H.
- Organizer
  18th International Symposium on Hepatitis C Virus and Related Viruses
- Place of Presentation
  シアトル、アメリカ合衆国
- Data Source
  KAKENHI-PROJECT-23590551
[Presentation] Metabolome analysis of the cultured hepatocytes persistently infected with Chimeric HCV (1b/2a).2011
- Author(s)
  Sugiyama, K, Saito H, Ebinuma H, Takaku H, Hibi T
- Organizer
  第70回日本癌学会総会
- Place of Presentation
  名古屋
- Data Source
  KAKENHI-PROJECT-23590551
[Presentation] Nrf2/sMaf転写因子複合体はHCVによる肝細胞脂肪蓄積に関与する2011
- Author(s)
  杉山和夫、海老沼浩利、酒瀬川典子、齋藤義正、金井隆典、日比紀文、齋藤英胤
- Organizer
  第70回日本癌学会総会
- Place of Presentation
  名古屋
- Data Source
  KAKENHI-PROJECT-23590551
[Presentation] Age and the liver stiffness measured by Fibroscan are significant predictive values for hepatoma development in chronic liver diseases2011
- Author(s)
  Ishibashi Y, Ebinuma H, Sugiyama K, Nakamoto N, Yamagishi Y, Usui S, Cho HS, Umeda R, Wakayama Y, Takaishi H, Kanai T, Sakamoto M, Saito H, Hibi T
- Organizer
  62nd Annual Meeting of the American Association for the Study of Liver Diseases
- Place of Presentation
  San Francisco, USA
- Data Source
  KAKENHI-PROJECT-23590551
[Presentation] Significant and continuous elevation of serum total cholesterol levels in patients with chronic hepatitis C who achieved sustained virological response by peginterferon and rivabirin treatment2011
- Author(s)
  Ebinuma H, Saito H, Sugiyama K, Nakamoto N, Yamagishi Y, Usui S, Cho HS, Umeda R, Ishibashi Y, Wakayama Y, Kanai T, Hibi T
- Organizer
  62nd Annual Meeting of the American Association for the Study of Liver Diseases
- Place of Presentation
  San Francisco, USA
- Data Source
  KAKENHI-PROJECT-23590551
[Presentation] Infectious hepatitis C virus bearing genotype-1b subgenomic replicon by trans-encapsidation with the structural regions of genotype 1b.2011
- Author(s)
  Sugiyama, K, Murakami Y, Hishiki T, Shimizu Y, Funami K, Ujino S, Saito H, Saito S, Kato N, Hibi T, Takaku H
- Organizer
  The 18th International Symposium on Hepatitis C Virus and Related Viruses
- Place of Presentation
  Seattle USA
- Data Source
  KAKENHI-PROJECT-23590551
[Presentation] 肝移植後の再発C型肝炎血清からの新しいHCVレプリコンの作製2007
- Author(s)
  杉山和夫、赤塚俊隆、下遠野邦忠
- Organizer
  第55回日本ウイルス学会学術集会
- Place of Presentation
  札幌
- Data Source
  KAKENHI-PROJECT-18590454
[Presentation] Establishment of a New HCV Replicon from the Recurrent HCV Patient Transplanted with Liver2007
- Author(s)
  Sugiyama K, Akatsuka T, Shimotohno T.
- Organizer
  14th International Symposium on Hepatitis C Virus and Related Viruses
- Place of Presentation
  Glasgow
- Data Source
  KAKENHI-PROJECT-18590454
[Presentation] Establishment of a new HCV replicon from the recurrent HCV patient transplanted with liver2007
- Author(s)
  Sugiyama K
- Organizer
  14th International Meeting on Hepatitis C Virus&Related Viruses
- Place of Presentation
  英国、グラスゴー
- Year and Date
  2007-09-09
- Data Source
  KAKENHI-PROJECT-18590454
[Presentation] Proteomics Analysis Identifies an Interaction between Hepatitis C Virus NS5B and alpha-tubulin2006
- Author(s)
  Inoue T, Huang C, Sugiyama K, Mizutani T, Hwang SB, Enomoto N, Lemon SM, Makino S
- Organizer
  13th International Symposium on Hepatitis C Virus and Related Viruses
- Place of Presentation
  Cairns
- Data Source
  KAKENHI-PROJECT-18590454
[Presentation] Hepatitis C virus affects the location and function of a drug-metabolizing enzyme, microsomal epoxide hydrolase2006
- Author(s)
  Akatsuka T, Kobayashi N, Sugiyama K, Duan H, Takagi A, Feinstone SM
- Organizer
  13th International Symposium on Hepatitis C Virus and Related Viruses
- Place of Presentation
  Cairns
- Data Source
  KAKENHI-PROJECT-18590454

1. SAITO Hidetsugu (80186949)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
2. KATO Nobuyuki (40150883)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
3. 斎藤英胤

# of Collaborated Projects: 0 results

# of Collaborated Products: 33 results
4. 下遠野邦忠

# of Collaborated Projects: 0 results

# of Collaborated Products: 1 results

SUGIYAMA Kazuo 杉山 和夫

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Metabolic Analysis of the Cultured Hepatic Cell Persistently Infected with Hepatitis C VirusPrincipal Investigator

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Establishment of the cell line supporting heptitis C virus replication efficiently and generation of an infectious clone of genotype 1bPrincipal Investigator

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Development of Replication System using A Hepatitis C Virus Infectious Clone and its ApplicationPrincipal Investigator

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Cell Cuiture System Supporting Hepatitis C Virus Replication by Using Infections RNAPrincipal Investigator

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[Book] がん生物学イラストレイテッド、腫瘍ウイルス(肝炎ウイルス)2011

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[Book] がん生物学イラストレイティド, 腫瘍ウイルス(肝炎ウイルス)2011

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[Book] Cancer Treatment Navigator(家族性腫瘍)(中川和彦編)2008

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[Book] Cancer Treatment Navigator (中川和彦編)2008

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[Journal Article] Prominent steatosis with hypermetabolism of the cell line permissive for years of infection with hepatitis C virus2014

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[Journal Article] Free cholesterol accumulation in hepatic stellate cells: Mechanism of liver fibrosis aggravation in nonalcoholic steatohepatitis in mice2014

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[Journal Article] C-C motif chemokine receptor 9 positive macrophages activate hepatic stellate cells and promote liver fibrosis in mice.2013

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[Journal Article] Suppressive Effect of the Histone Deacetylase Inhibitor, Suberoylanilide Hydroxamic Acid (SAHA), on Hepatitis C Virus Replication via Epigenetic Changes in Host Cells2013

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[Journal Article] Hepatitis C Virus Infection Induces Inflammatory Cytokines and Chemokines Mediated by the Cross Talk between Hepatocytes and Stellate Cells.2013

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[Journal Article] A high-cholesterol diet exacerbates liver fibrosis in mice via accumulation of free cholesterol in hepatic stellate cells2012

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[Journal Article] The interaction between human initiation factor eIF3 subunit c and heat-shock protein 90: a necessary factor for translation mediated by the hepatitis C virus internal ribosome entry site.2012

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[Journal Article] p53/p66Shc-mediated signaling contributes to the progression of non-alcoholic steatohepatitis in humans and mice.2012

SUGIYAMA Kazuo 杉山和夫

[Presentation] Epigenetics作用薬を用いたC型肝炎ウイルスの制御　ヒストン脱アセチル化阻害薬の有用性2013