Akiyama Hiroshi 穐山浩

… Alternative Names

穐山浩アキヤマヒロシ

AKIYAMA Hiroshi 穐山浩

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Researcher Number	10260259
Other IDs	https://orcid.org/0000-0002-7764-8601
Affiliation (Current)	2025: 星薬科大学, 薬学部, 教授
Affiliation (based on the past Project Information) *help	2023: 星薬科大学, 薬学部, 教授 2015 – 2016: 国立医薬品食品衛生研究所, 食品部, 部長 2014: 国立医薬品食品衛生研究所, 食品添加物部, 部長 2007 – 2008: National Institute of Health Sciences, 代謝生化学部, 室長 2006: 国立医薬品食品衛生研究所, 食品部, 室長
Review Section/Research Field	Principal Investigator Environmental and hygienic pharmacy / アレルギー Except Principal Investigator Basic Section 54020:Connective tissue disease and allergy-related / Epidemiology and preventive medicine / Eating habits, studies on eating habits
Keywords	Principal Investigator オボアルブミン / 食物アレルギー / アレルギー / 医薬部外品 / 医薬品添加物 / インビトロ / 評価法 / エリスリトール / 食品添加物 / HLA-DR … More / ハプテン抗原 / ケモカイン / 樹状細胞 / 抗原感作性 / アレルゲン / Th2バランス / Th1 / サイトカイン / ヒスタミン / B10Aマウス / β-カロテン … More Except Principal Investigator 学校 / アレルギー表示 / 給食 / アレルギー症状誘発確率 / 定量的リスク評価 / 食物アレルギー / コチニール色素特異的IgE / 経皮感作 / 即時型アレルギー / アナフィラキシー / カルミン酸 / 38kDa豊富分画 / 2D-Western blot法 / 特異的IgE抗体 / プリックテスト / コチニール色素アレルギー / ニバレノール / ハーブ / エッグボックス / 減衰 / ペクチン / ペクチンゲル / 吸収率 / マウス / デオキシニバレノール / カビ毒 / 安全性 / 調理・加工 / デトックス Less

Quantitative risk assessment of unintended allergens in school-provided lunch and food service at nursery.
- Principal Investigator
  
  福家辰樹
- Project Period (FY)
  2023 – 2025
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Review Section
  
  Basic Section 54020:Connective tissue disease and allergy-related
- Research Institution
  National Center for Child Health and Development
Study on the development of evaluation method for the sensitization of food additivesPrincipal Investigator
- Principal Investigator
  
  Akiyama Hiroshi
- Project Period (FY)
  2014 – 2016
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Research Field
  
  Environmental and hygienic pharmacy
- Research Institution
  National Institute of Health Sciences
Anaphylaxis due to cochineal dye: the confirmation of the diagnostic method and the review of Japanese cases
- Principal Investigator
  
  Takeo Naoko
- Project Period (FY)
  2013 – 2016
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Research Field
  
  Epidemiology and preventive medicine
- Research Institution
  Oita University
New approach for detoxication of toxic substances in foods and the evaluation
- Principal Investigator
  
  KONISHI Yoshiko
- Project Period (FY)
  2007 – 2009
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Research Field
  
  Eating habits, studies on eating habits
- Research Institution
  National Institute of Health Sciences
CarotenoidsCarotenoides intake inhibits the oral sensitization and the development of food allergyPrincipal Investigator
- Principal Investigator
  
  AKIYAMA Hiroshi
- Project Period (FY)
  2006 – 2008
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Research Field
  
  アレルギー
- Research Institution
  National Institute of Health Sciences

All 2017 2016 2015 2014 2008 2007 2006 Other

All Journal Article Presentation

[Journal Article] Evaluation of the safety and efficacy of Glycyrrhiza uralensis root extracts produced using artificial hydroponic and artificial hydroponic-field hybrid cultivation systems2017
- Author(s)
  H. Akiyama, M. Nose, N. Ohtsuki, S. Hisaka, H. Takiguchi, A. Tada, N. Sugimoto, H. Fuchino, T. Inui, N. Kawano, S. Hayashi, A. Hishida, T. Kudo, K. Sugiyama, Y. Abe, M. Mutsuga, N. Kawahara, K. Yoshimatsu
- Journal Title
  
  J. Nat. Med.
  
  Volume: 71 Issue: 1 Pages: 265-271
- DOI
  10.1007/s11418-016-1058-1
- Peer Reviewed / Acknowledgement Compliant
- Data Source
  KAKENHI-PROJECT-26460185
[Journal Article] Development of an analytical method for copper chlorophyll and sodium copper chlorophyllin in processed foods2016
- Author(s)
  Ippei Suzuki, Hiroki Kubota, Shoko Terami, Takahiko Hara, Yoshinori Hirakawa, Tayoshi Iizuka, Chiye Tatebe, Takashi Ohtsuki, Takeo Yano, Kyoko Sato, Hiroshi Akiyama
- Journal Title
  
  Japanese Journal of Food Chemistry and Safety
  
  Volume: 23 Pages: 55-62
- NAID
  130005262985
- Peer Reviewed / Acknowledgement Compliant / Open Access
- Data Source
  KAKENHI-PROJECT-26460185
[Journal Article] A method for the detection of shrimp/prawn and crab DNAs to identify allergens in dried seaweed products2015
- Author(s)
  265Hashimoto H, Hongo T, Hayashi C, Nakamura K, Nakanishi K, Ikeda M, Adachi R, Akiyama H, Teshima R,
- Journal Title
  
  Japanese J. Food Chem. Safety
  
  Volume: 22 Pages: 1-10
- NAID
  110009934911
- Peer Reviewed / Acknowledgement Compliant / Open Access
- Data Source
  KAKENHI-PROJECT-26460185
[Journal Article] A method for the detection of shrimp/prawn and crab DNAs to identify allergens in dried seaweed products2015
- Author(s)
  Hiroyuki Hashimoto, Takeshi Hongo, Chieko Hayashi, Kazuhiro Nakamura, Kiyoko Nakanishi, Megumi Ikeda, Reiko Adachi, Hiroshi Akiyama, Reiko Teshima, Takeo Yano
- Journal Title
  
  Japanese Journal of Food Chemistry and Safety
  
  Volume: 22 Pages: 1-10
- NAID
  110009934911
- Peer Reviewed / Acknowledgement Compliant
- Data Source
  KAKENHI-PROJECT-26460185
[Journal Article] Evaluation of gardenia yellow using crocetin from alkaline hydrolysis based on ultra high performance liquid chromatography and high-speed countercurrent.2014
- Author(s)
  K. Inoue, C. Tanada, H. Nishikawa, S. Matsuda, A. Tada, Y. Ito, J.-Z. Min, K. Todoroki, N. Sugimoto, T. Toyo'oka, H. Akiyama
- Journal Title
  
  J. Sep. Sci.
  
  Volume: 37 Issue: 24 Pages: 3619-3624
- DOI
  10.1002/jssc.201400793
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-25460040, KAKENHI-PROJECT-26460185
[Journal Article] フランス製菓子赤色マカロン摂取後に生じた、コチニール色素によるアナフィラキシーの２症例2014
- Author(s)
  原田晋、山川有子、杉本直樹、穐山浩
- Journal Title
  
  J Environ Dermatol Cutan Allergol
  
  Volume: 8 Pages: 180-186
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-26460185
[Journal Article] コチニールによるアナフィラキシー2014
- Author(s)
  原田晋、穐山浩、杉本直樹、山川有子
- Journal Title
  
  皮膚臨床
  
  Volume: 56 Pages: 1896-1902
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-26460185
[Journal Article] 化粧品・医薬部外品中の乳アレルゲンタンパク質の分析2014
- Author(s)
  258大月典子、杉本理恵、佐藤恭子、杉本直樹、秋山卓美、豊田正武、穐山浩
- Journal Title
  
  日本食品化学学会誌
  
  Volume: 21 Pages: 155-164
- NAID
  110009900882
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-26460185
[Journal Article] Development and validation of a lateral flow assay for the detection of crustacean protein in processed foods2014
- Author(s)
  241Koizumi D, Shirota K, Akita R, Oda H, Akiyama H
- Journal Title
  
  Food Chemistry
  
  Volume: 150 Pages: 348-352
- DOI
  10.1016/j.foodchem.2013.10.130
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-26460185
[Journal Article] ドイツ製ブラッドオレンジジュースに含まれていたコチニール色素によるアナフィラキシーの1例2014
- Author(s)
  原田晋、穐山浩、杉本直樹、山川有子
- Journal Title
  
  皮膚臨床
  
  Volume: 56 Pages: 1247-1251
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-26460185
[Journal Article] フランス製赤色マカロンに含まれるコチニール色素が原因とと思われるアナフィラキシーの1例　―　最近のコチニールアレルギーについて2014
- Author(s)
  山川有子、山野朋子、穐山浩、池澤善郎
- Journal Title
  
  皮膚臨床
  
  Volume: 56 Pages: 1241-1245
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-26460185
[Journal Article] Examination of Processed Vegetable Foods for the Presence of Common DNA Sequences of Genetically Modified Tomatoes2014
- Author(s)
  北川麻美子、中村公亮、近藤一成、生形省次、穐山浩
- Journal Title
  
  Food Hygiene and Safety Science (Shokuhin Eiseigaku Zasshi)
  
  Volume: 55 Issue: 6 Pages: 247-253
- DOI
  10.3358/shokueishi.55.247
- NAID
  130004812649
- ISSN
  0015-6426, 1882-1006
- Language
  Japanese
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-26460185
[Journal Article] 食べ物にアレルギーに対する効果とは?2008
- Author(s)
  穐山浩
- Journal Title
  
  Q&Aでわかるアレルギー疾患 4
  
  Pages: 327-329
- Data Source
  KAKENHI-PROJECT-18604011
[Journal Article] Specific detection of wheat residues in processed foods by polymerase chain reaction2007
- Author(s)
  Yamakawa, H., Akiyama, H., Endo, Y., Miyatake, K, Sakata, K., Sakai, S., Toyoda, M., Urisu, A
- Journal Title
  
  Biosci, Biotechnol, and Biochem, 71
  
  Pages: 2561-2564
- NAID
  10027520225
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-19500675
[Journal Article] Cross Reactivity of Allergen2007
- Author(s)
  Hiroshi AKIYAMA
- Journal Title
  
  Japanese Joumal of Pediatric Medicine 39
  
  Pages: 558-563
- Data Source
  KAKENHI-PROJECT-18604011
[Journal Article] Chondroitin sulfate intake inhibits the IgE-mediated allergic response by down-regulating Th2 responses in mice2006
- Author(s)
  Shinobu Sakai, Hiroshi Akiyama、他6人(contributed equally)
- Journal Title
  
  Journal of Biological Chemistry 281
  
  Pages: 19872-19880
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-18604011
[Journal Article] Linhardt Immunological Activity of Chondroitin Sulfate2006
- Author(s)
  Tohsihiko Toida, Shinobu Sakai, Hiroshi Akiyama, and Robert J.
- Journal Title
  
  Advances in Pharmacology 53
  
  Pages: 403-415
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-18604011
[Journal Article] Chondroitin sulfate intake inhibits the IgE-mediated allergic response by down-regulating Th2 responses in mice2006
- Author(s)
  Shinobu Sakai, Hirohi Akiyama
- Journal Title
  
  Journal of Biological Chemistry 281
  
  Pages: 19872-19880
- Data Source
  KAKENHI-PROJECT-18604011
[Journal Article] Effect of oral administration of CpG ODN-OVA on WBB6F1-W/Wv mice2006
- Author(s)
  Reiko Teshima, Okunuki H, Sato Y, Akiyama H, 他2名
- Journal Title
  
  Allergology International 55
  
  Pages: 43-48
- NAID
  10020557497
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-18604011
[Presentation] Total determination of chloramphenicol and chloramphenicol glucuronide residues in foods by liquid chromatography-tandem mass spectrometry2016
- Author(s)
  Hiroyuki Kikuchi, Takatoshi Sakai, Reiko Teshima, Satoru Nemoto, and Hiroshi Akiyama
- Organizer
  第130回AOACインターナショナル年会
- Place of Presentation
  ダラス（米国）
- Year and Date
  2016-09-18
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-26460185
[Presentation] 未変成の食品加工用酵素の抗原感作性評価2016
- Author(s)
  片山茂，福島悠依子，三谷塁一，穐山浩，中村宗一郎
- Organizer
  日本食品化学学会第22回学術大会
- Place of Presentation
  高知市
- Year and Date
  2016-06-02
- Data Source
  KAKENHI-PROJECT-26460185
[Presentation] Japanese risk management for food additives2016
- Author(s)
  Hiroshi Akiyama
- Organizer
  2016 Food Fraud Symposium
- Place of Presentation
  ソウル（韓国）
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-26460185
[Presentation] コチニール色素アレルギーの診断の際のプリックテストと特異的IgE抗体測定の有用性2016
- Author(s)
  竹尾直子、藤原作平、中村政志、矢上晶子、松永佳世子、穐山浩、中山哲
- Organizer
  第275回　日本皮膚科学会東海地方会
- Place of Presentation
  名古屋国際会議場（愛知県名古屋市）
- Year and Date
  2016-03-20
- Data Source
  KAKENHI-PROJECT-25460764
[Presentation] 人工水耕栽培により生産した甘草の有効性評価について2015
- Author(s)
  能勢充彦、穐山浩、滝口肇、大月典子、多田敦子、杉本直樹、工藤善、渕野裕之、乾貴幸、河野徳昭、林茂樹、菱田敦之、川原信夫、吉松嘉代
- Organizer
  日本食品化学学会第21回大会
- Place of Presentation
  東京
- Year and Date
  2015-05-21
- Data Source
  KAKENHI-PROJECT-26460185
[Presentation] Japanese Framework for labeling and testing of allergens in foods2015
- Author(s)
  Hiroshi Akiyama, Reiko Adachi
- Organizer
  Pacifichem 2015 THE INTERNATIONAL CHEMICAL CONGRESS OF PACIFIC BASIN SOCIETIES
- Place of Presentation
  Honolulu, Hawaii, USA
- Year and Date
  2015-12-15
- Invited / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-26460185
[Presentation] 人工水耕栽培により生産した黄連の安全性・有効性評価について2015
- Author(s)
  滝口肇、能勢充彦、杉山圭一、大月典子、多田敦子、杉本直樹、工藤善、渕野裕之、乾貴幸、河野徳昭、川原信夫、吉松嘉代、穐山浩
- Organizer
  日本食品化学学会第21回大会
- Place of Presentation
  東京
- Year and Date
  2015-05-21
- Data Source
  KAKENHI-PROJECT-26460185
[Presentation] Carotenoid intake inhibits the oral sensitization and development of food allergies.2008
- Author(s)
  Hiroshi Akiyama
- Organizer
  日本免疫毒性学会
- Place of Presentation
  東京
- Year and Date
  2008-09-12
- Data Source
  KAKENHI-PROJECT-18604011
[Presentation] Carotenoid intake inhibits the oral sensitization and development of food allergies2008
- Author(s)
  Hiroshi Akiyama
- Organizer
  日本免疫毒性学会
- Place of Presentation
  東京
- Year and Date
  2008-09-12
- Data Source
  KAKENHI-PROJECT-18604011
[Presentation] Prevention of food allergy development by food factors2007
- Author(s)
  Hiroshi Akiyama
- Organizer
  The International Conference on Food Factors for Health Promotion(ICOFF2007)
- Place of Presentation
  京都
- Year and Date
  2007-11-30
- Data Source
  KAKENHI-PROJECT-18604011
[Presentation] Prevention of food allergy development by food factors2007
- Author(s)
  Hiroshi Akiyama
- Organizer
  The International Conference on Food Factors for Health Promotion (ICOFF2007)
- Place of Presentation
  京都
- Year and Date
  2007-11-30
- Data Source
  KAKENHI-PROJECT-18604011
[Presentation] Dietary apple procyanidins inhibit the development of oral sensitization and food allergies2007
- Author(s)
  Hiroshi Akiyama
- Organizer
  The3rd International Conference on Polyphenols and Health (ICPH 2007)
- Place of Presentation
  京都
- Year and Date
  2007-11-26
- Data Source
  KAKENHI-PROJECT-18604011
[Presentation] 化粧品・医薬部外品中の乳アレルゲンタンパク質の分析について
- Author(s)
  大月典子、杉本理恵、佐藤恭子、杉本直樹、秋山卓美、豊田正武、穐山浩
- Organizer
  日本食品化学学会第２０回総会・学術大会
- Place of Presentation
  東京ビックサイト
- Year and Date
  2014-05-21 – 2014-05-23
- Data Source
  KAKENHI-PROJECT-26460185
[Presentation] DNAマイクロアレイによる未承認遺伝子組換えパパイヤのスクリーニング検査法
- Author(s)
  伊東篤志、田口朋之、田名網健雄、羽田聖治、中村公亮、近藤一成、穐山浩、手島玲子、何思厳、宮原平、山田晃代、小関良宏
- Organizer
  日本食品化学学会第２０回総会・学術大会
- Place of Presentation
  東京ビックサイト
- Year and Date
  2014-05-21 – 2014-05-23
- Data Source
  KAKENHI-PROJECT-26460185
[Presentation] 樹状細胞の遊走能を指標とした抗原感作性評価法確立
- Author(s)
  福島悠依子、片山茂、小俣洋奈、穐山浩、中村宗一郎
- Organizer
  日本食品化学学会第２1回総会・学術大会
- Place of Presentation
  東京ビックサイト
- Year and Date
  2015-05-20 – 2015-05-22
- Data Source
  KAKENHI-PROJECT-26460185
[Presentation] 抗原提示能を有するTHP-1由来樹状細胞系の確立とその応用
- Author(s)
  小俣洋奈、片山茂、大野史晃、真壁秀文、穐山浩、中村宗一郎
- Organizer
  日本栄養食糧学会
- Place of Presentation
  酪農学園大学
- Year and Date
  2014-05-30 – 2014-06-01
- Data Source
  KAKENHI-PROJECT-26460185
[Presentation] リスク管理における食品添加物の分析法について
- Author(s)
  穐山浩
- Organizer
  第27回バイオメディカル分析科学シンポジウム
- Place of Presentation
  帝京大学薬学部
- Year and Date
  2014-08-20 – 2014-08-21
- Invited
- Data Source
  KAKENHI-PROJECT-26460185

1. KONISHI Yoshiko (10195761)

# of Collaborated Projects: 3 results

# of Collaborated Products: 0 results
2. KATAYAMA Shigeru (30443922)

# of Collaborated Projects: 1 results

# of Collaborated Products: 3 results
3. NAKAMURA kousuke (60570926)

# of Collaborated Projects: 1 results

# of Collaborated Products: 6 results
4. SUGIMOTO Naoki (50300918)

# of Collaborated Projects: 1 results

# of Collaborated Products: 8 results
5. Takeo Naoko (30423693)

# of Collaborated Projects: 1 results

# of Collaborated Products: 1 results
6. Matsunaga kayoko (80131192)

# of Collaborated Projects: 1 results

# of Collaborated Products: 1 results
7. 杉浦伸一 (30359749)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
8. 福家辰樹 (10535842)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
9. 鈴木美成 (40469987)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
10. 轟木堅一郎

# of Collaborated Projects: 0 results

# of Collaborated Products: 1 results

Akiyama Hiroshi 穐山 浩

穐山 浩 アキヤマ ヒロシ

AKIYAMA Hiroshi 穐山 浩

Research Projects

Research Products

Co-Researchers

Quantitative risk assessment of unintended allergens in school-provided lunch and food service at nursery.

Principal Investigator

Project Period (FY)

Research Category

Review Section

Research Institution

Study on the development of evaluation method for the sensitization of food additivesPrincipal Investigator

Principal Investigator

Project Period (FY)

Research Category

Research Field

Research Institution

Anaphylaxis due to cochineal dye: the confirmation of the diagnostic method and the review of Japanese cases

Principal Investigator

Project Period (FY)

Research Category

Research Field

Research Institution

New approach for detoxication of toxic substances in foods and the evaluation

Principal Investigator

Project Period (FY)

Research Category

Research Field

Research Institution

CarotenoidsCarotenoides intake inhibits the oral sensitization and the development of food allergyPrincipal Investigator

Principal Investigator

Project Period (FY)

Research Category

Research Field

Research Institution

[Journal Article] Evaluation of the safety and efficacy of Glycyrrhiza uralensis root extracts produced using artificial hydroponic and artificial hydroponic-field hybrid cultivation systems2017

Author(s)

Journal Title

DOI

Data Source

[Journal Article] Development of an analytical method for copper chlorophyll and sodium copper chlorophyllin in processed foods2016

Author(s)

Journal Title

NAID

Data Source

[Journal Article] A method for the detection of shrimp/prawn and crab DNAs to identify allergens in dried seaweed products2015

Author(s)

Journal Title

NAID

Data Source

[Journal Article] A method for the detection of shrimp/prawn and crab DNAs to identify allergens in dried seaweed products2015

Author(s)

Journal Title

NAID

Data Source

[Journal Article] Evaluation of gardenia yellow using crocetin from alkaline hydrolysis based on ultra high performance liquid chromatography and high-speed countercurrent.2014

Author(s)

Journal Title

DOI

Data Source

[Journal Article] フランス製菓子赤色マカロン摂取後に生じた、コチニール色素によるアナフィラキシーの２症例2014

Author(s)

Journal Title

Data Source

[Journal Article] コチニールによるアナフィラキシー2014

Author(s)

Journal Title

Data Source

[Journal Article] 化粧品・医薬部外品中の乳アレルゲンタンパク質の分析2014

Author(s)

Journal Title

NAID

Data Source

[Journal Article] Development and validation of a lateral flow assay for the detection of crustacean protein in processed foods2014

Author(s)

Journal Title

DOI

Data Source

[Journal Article] ドイツ製ブラッドオレンジジュースに含まれていたコチニール色素によるアナフィラキシーの1例2014

Akiyama Hiroshi 穐山浩

穐山浩アキヤマヒロシ

AKIYAMA Hiroshi 穐山浩

[Journal Article] フランス製赤色マカロンに含まれるコチニール色素が原因とと思われるアナフィラキシーの1例　―　最近のコチニールアレルギーについて2014