Kume Akihiro 久米晃啓

… Alternative Names

久米晃啓クメアキヒロ

KUME Akihiro 久米晃啓

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Researcher Number	10264293
Other IDs
Affiliation (Current)	2025: 自治医科大学, 医学部, 客員教授
Affiliation (based on the past Project Information) *help	2018 – 2020: 自治医科大学, 医学部, 教授 2007 – 2014: Jichi Medical University, 医学部, 准教授 2000 – 2006: Jichi Med.Sch., Faculty of Medicine, Associate Professor, 医学部, 助教授 1999: 自治医学大学, 医学部, 講師 1997 – 1999: 自治医科大学, 医学部, 講師 1995: 熊本大学, 医学部, 助手
Review Section/Research Field	Principal Investigator Pediatrics / Pediatrics / Biological Sciences / Hematology / Basic Section 52050:Embryonic medicine and pediatrics-related / Embryonic/Neonatal medicine Except Principal Investigator Hematology / Hematology / Virology / Embryonic/Neonatal medicine
Keywords	Principal Investigator 遺伝子治療 / gene therapy / トランスレーショナルリサーチ / レトロウイルスベクター / 造血幹細胞 / chronic granulomatous disease / 慢性肉芽腫症 / 移植・再生医療 / green fluorescent protein / 選択的増幅遺伝子 … More / 癌 / アデノ随伴ウイルス / translational research / hematopoietic stem cells / ゲノム / 遺伝子 / 先天代謝異常 / 内在性ウイルス / 細胞基質 / ウイルス汚染 / 細胞基材 / バイオ医薬品 / cell and tissue / transplantation / エリスロポエチン受容体 / 浩血幹細胞 / 選択的増幅潰伝子 / 浩血微小環境 / 慢性肉弾腫症 / 顆粒球コロニー増殖因子受容体 / エリスロポチエン受容体 / 骨髄腔内注入法 / 造血微小環境 / 細胞・組織 / phagocytes / innate immunity / retroviral vector / selecvtive amplifier gene / 活性酸素 / 食細胞 / 自然免疫 / selective amplifier gene / 緑色蛍光蛋白質 / hematopoietic stem cell / retrovirus vector / green flnogescent protein / ヒストン修飾 / エピジェネティクス / フェニルケトン尿症 / 栄養学 / 小児代謝 / ウイルスベクター / 新生児 / ウィルス / 免疫学 / 血管新生 … More Except Principal Investigator 遺伝子導入 / 遺伝子治療 / ITR / Rep / Gene transfer / AAVS1領域 / AAVベクター / 選択的増幅遺伝子 / 造血幹細胞 / Msx1 / AAV vector / TVI method / TVI法 / AAV / ex vivo expansion / in vivo expansion / Selective amplifier gene / Hematopoietic stem cell / Gene therapy / 体外増幅 / 体内増幅 / 遺伝子組込み / パッケージング細胞株 / エストロゲン受容体 / G-CSF受容体 / Stem cell / Hematopoietic system / Skeletal muscle / Plasticity / Transdifferentiation / Dedifferentiation / AVVベクター / 幹細胞 / 造血系 / 骨格筋 / 可塑性 / 分化転換 / 脱分化 / AAVS1 locus / packaging cell line / differentiation-regulatory gene / 分化制御遺伝子 / Clover yellow vein virus / protease / Rep protein / nuclear proteins / packaging cells / adeno-associated virus vector / クローバーイエローベインウイルス / プロテアーゼ / Rep蛋白質 / 核蛋白質 / パッケージング細胞 / アデノ随伴ウイルス / AAVSI locus / Integration / Gene theray / Estrogen receptor / G-CSF receptor / 対外増幅 / 遺伝子 / 転写因子 / 遺伝子多型 / サイトカイン / 臍帯血 / 早産児 / 新生児 / 免疫学 / ヘルパープラスミド / 分化シグナル / 増殖シグナル Less

Establishment of virus-free cell substrates for protein drug productionPrincipal Investigator
- Principal Investigator
  
  Kume Akihiro
- Project Period (FY)
  2018 – 2020
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Review Section
  
  Basic Section 52050:Embryonic medicine and pediatrics-related
- Research Institution
  Jichi Medical University
Genome instability caused by EVI1 oncogene activationPrincipal Investigator
- Principal Investigator
  
  KUME Akihiro
- Project Period (FY)
  2011 – 2013
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Research Field
  
  Pediatrics
- Research Institution
  Jichi Medical University
Immunological analysis of neonatal diseases by profile assays of cytokines, cytokine-related genes and transcription factors
- Principal Investigator
  
  TAKAHASHI Naoto
- Project Period (FY)
  2010 – 2014
- Research Category
  
  Grant-in-Aid for Scientific Research (B)
- Research Field
  
  Embryonic/Neonatal medicine
- Research Institution
  The University of Tokyo
  Jichi Medical University
Extrahepatic tissue-targeted gene therapy for phenylketonuriaPrincipal Investigator
- Principal Investigator
  
  KUME Akihiro
- Project Period (FY)
  2008 – 2010
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Research Field
  
  Pediatrics
- Research Institution
  Jichi Medical University
新規クロマチンインシュレータを搭載した遺伝子治療ベクターの開発Principal Investigator
- Principal Investigator
  
  久米晃啓
- Project Period (FY)
  2006 – 2007
- Research Category
  
  Grant-in-Aid for Scientific Research on Priority Areas
- Review Section
  
  Biological Sciences
- Research Institution
  Jichi Medical University
新生児期遺伝子治療におけるアデノ随伴ウイルスベクターの体内動態と治療効果Principal Investigator
- Principal Investigator
  
  久米晃啓
- Project Period (FY)
  2005 – 2006
- Research Category
  
  Grant-in-Aid for Exploratory Research
- Research Field
  
  Embryonic/Neonatal medicine
- Research Institution
  Jichi Medical University
DEDIFFERENTIATION OF NON-HEMATOPOIETIC TISSUE BY GENETIC MANIPULATION AND ITS ACQUISITION OF PLASTICITY AND HEMATOPOIETIC TRANSDIFFERENTIATION
- Principal Investigator
  
  OZAWA Keiya
- Project Period (FY)
  2004 – 2005
- Research Category
  
  Grant-in-Aid for Scientific Research (B)
- Research Field
  
  Hematology
- Research Institution
  JICHI MEDICAL UNIVERSITY
Gene therapy for chronic granulomatous disease in combination with selective cell amplification and utilizing hematopoietic microenvironmentPrincipal Investigator
- Principal Investigator
  
  KUME Akihiro
- Project Period (FY)
  2004 – 2006
- Research Category
  
  Grant-in-Aid for Scientific Research (B)
- Research Field
  
  Pediatrics
- Research Institution
  JICHI MEDICAL UNIVERSITY
キメラ受容体遺伝子導入による白血病細胞療法の効果増強Principal Investigator
- Principal Investigator
  
  久米晃啓
- Project Period (FY)
  2002
- Research Category
  
  Grant-in-Aid for Scientific Research on Priority Areas
- Review Section
  
  Biological Sciences
- Research Institution
  Jichi Medical University
Gene therapy for chronic granulomatous disease combined with in vivo expansion of transduced hematopoietic cells.Principal Investigator
- Principal Investigator
  
  KUME Akihiro
- Project Period (FY)
  2002 – 2003
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Research Field
  
  Pediatrics
- Research Institution
  Jichi Medical School
AAVベクターによる抗腫瘍血管療法と新規アデノ-AAVハイブリッドベクターの開発Principal Investigator
- Principal Investigator
  
  久米晃啓
- Project Period (FY)
  2000
- Research Category
  
  Grant-in-Aid for Scientific Research on Priority Areas (C)
- Review Section
  
  Biological Sciences
- Research Institution
  Jichi Medical University
Development of the gene therapy technologies using adeno-associated virus (AAV)
- Principal Investigator
  
  OZAWA Keiya
- Project Period (FY)
  2000 – 2001
- Research Category
  
  Grant-in-Aid for Scientific Research (B)
- Research Field
  
  Hematology
- Research Institution
  Jichi Medical School
Development and application of the technologies for manipulationg hematopoietic stem cells using cell-regulatory genes
- Principal Investigator
  
  OZAWA Keiya
- Project Period (FY)
  1999 – 2000
- Research Category
  
  Grant-in-Aid for Scientific Research (B).
- Research Field
  
  Hematology
- Research Institution
  Jichi Medical School
Gene therapy of chronic granulomatous disease with GFP-tagged retrovirus vectorsPrincipal Investigator
- Principal Investigator
  
  KUME Akihiro
- Project Period (FY)
  1999 – 2000
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Research Field
  
  Pediatrics
- Research Institution
  Jichi Medical University
Gene transfer into hematopoietic stem cells and gene therapy for chronic granulomatous diseasePrincipal Investigator
- Principal Investigator
  
  KUME Akihiro
- Project Period (FY)
  1999 – 2001
- Research Category
  
  Grant-in-Aid for Scientific Research (B)
- Research Field
  
  Hematology
- Research Institution
  Jichi Medical School
Development of the method for chromosomal site-specific integration of transgenes using AAV and its application to hematopoietic cells
- Principal Investigator
  
  OZAWA Keiya
- Project Period (FY)
  1998 – 1999
- Research Category
  
  Grant-in-Aid for Scientific Research (B)
- Research Field
  
  Hematology
- Research Institution
  Jichi Medical School
Establishment of a producer cell line for adeno-associated virus vector using a novel system regulating nuclear protein
- Principal Investigator
  
  URABE Masashi
- Project Period (FY)
  1998 – 1999
- Research Category
  
  Grant-in-Aid for Scientific Research (B)
- Research Field
  
  Virology
- Research Institution
  Jichi Medical School
造血幹細胞を標的とした遺伝子治療のための新規選択的増幅遺伝子の開発
- Principal Investigator
  
  OZAWA Keiya
- Project Period (FY)
  1997
- Research Category
  
  Grant-in-Aid for Scientific Research on Priority Areas
- Research Institution
  Jichi Medical University
がん遺伝子治療への応用を目指したアデノ随伴ウイルスペクターシステムの開発
- Principal Investigator
  
  小澤敬也
- Project Period (FY)
  1997
- Research Category
  
  Grant-in-Aid for Scientific Research on Priority Areas
- Research Institution
  Jichi Medical University
Development of a novel regulatory gene for in vivo & in vitro expansion of transduced hematopoietic stem cellss
- Principal Investigator
  
  OZAWA Keiya
- Project Period (FY)
  1997 – 1998
- Research Category
  
  Grant-in-Aid for Scientific Research (B)
- Research Field
  
  Hematology
- Research Institution
  Jichi Medical School
Development of GFP-tagged retrovirus vectors for gene therapyPrincipal Investigator
- Principal Investigator
  
  KUME Akihiro
- Project Period (FY)
  1997 – 1998
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Research Field
  
  Pediatrics
- Research Institution
  Jichi Medical School
自家蛍光標識レトロウイルスによる造血幹細胞マ-キングPrincipal Investigator
- Principal Investigator
  
  久米晃啓
- Project Period (FY)
  1995
- Research Category
  
  Grant-in-Aid for Encouragement of Young Scientists (A)
- Research Field
  
  Hematology
- Research Institution
  Kumamoto University

[Book] バイオ医薬品・再生医療等製品開発のためのカルタヘナ法2018
- Author(s)
  久米　晃啓
- Total Pages
  121
- Publisher
  サイエンス＆テクノロジー
- ISBN
  9784864281775
- Data Source
  KAKENHI-PROJECT-18K07853
[Journal Article] Aspects of Gene Therapy Products Using Current Genome-Editing Technology in Japan2020
- Author(s)
  Yamaguchi Teruhide、Uchida Eriko、Okada Takashi、Ozawa Keiya、Onodera Masafumi、Kume Akihiro、Shimada Takashi、Takahashi Satoru、Tani Kenzaburo、Nasu Yasutomo、Mashimo Tomoji、Mizuguchi Hiroyuki、Mitani Kohnosuke、Maki Kazushige
- Journal Title
  
  Human Gene Therapy
  
  Volume: 31 Issue: 19-20 Pages: 1043-1053
- DOI
  10.1089/hum.2020.156
- NAID
  120007147867
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-18H03974, KAKENHI-PROJECT-18K07853, KAKENHI-PROJECT-23K20328
[Journal Article] AAV6-mediated IL-10 expression in the lung ameliorates bleomycin-induced pulmonary fibrosis.2018
- Author(s)
  Kurosaki F, Uchibori R, Mato N, Sehara Y, SagaY, Urabe M, Mizukami H, Sugiyama Y, Kume A
- Journal Title
  
  Human Gene Therapy
  
  Volume: 29 Pages: 1242-1251
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-18K07853
[Journal Article] Novel anti-tumor mechanism of galanin receptor type 2 in head and neck squamous cell carcinoma cells2014
- Author(s)
  Uehara T, Kanazawa T, Mizukami H, Uchibori R, Tsukahara T, Urabe M, Kume A, Misawa K, Carey T, Suzuki M, Ichimura K, Ozawa K
- Journal Title
  
  Cancer Science
  
  Volume: 105 Issue: 1 Pages: 72-80
- DOI
  10.1111/cas.12315
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-23591548, KAKENHI-PROJECT-24390247, KAKENHI-PROJECT-24592594, KAKENHI-PROJECT-25430155, KAKENHI-PROJECT-25461460
[Journal Article] Novel anti-tumor mechanism of galanin receptor type 2 in head and neck squamous cell carcinoma cells2014
- Author(s)
  Uehara T, Kanazawa T, Mizukami H, Uchibori R, Tsukahara T, Urabe M, Kume A, Misawa K, Carey T, Suzuki M, Ichimura K, Ozawa K.
- Journal Title
  
  Cancer Sci
  
  Volume: 105 Pages: 72-80
- Data Source
  KAKENHI-PROJECT-23591548
[Journal Article] NF-κB activity regulates mesenchymal stem cell accumulation at tumor sites.2013
- Author(s)
  Uchibori R, Tsukahara T, Mizuguchi H, Saga Y, Urabe M, Mizukami H, Kume A, Ozawa K
- Journal Title
  
  Cancer Research
  
  Volume: 73 Issue: 1 Pages: 364-372
- DOI
  10.1158/0008-5472.can-12-0088
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-23591548, KAKENHI-PROJECT-23659493, KAKENHI-PROJECT-24390247, KAKENHI-PROJECT-24700995, KAKENHI-PROJECT-25430155
[Journal Article] CD19 target-engineered T-cells accumulate at tumor lesions in human B-cell lymphoma xenograft mouse models2013
- Author(s)
  Tsukahara T, Ohmine K, Yamamoto C, Uchibori R, Ido H, Teruya T, Urabe M, Mizukami H, Kume A, Nakamura M, Mineno J, Takesako K, Riviere I, Sadelain M, Brentjens R, Ozawa K.
- Journal Title
  
  Biochem Biophys Res Commun
  
  Volume: 438 Pages: 84-89
- Data Source
  KAKENHI-PROJECT-23591548
[Journal Article] NF-B activity regulates mesenchymal stem cell accumulation at tumor sites2013
- Author(s)
  Uchibori R, Tsukahara T, Mizuguchi H, Saga Y, Urabe M, Mizukami H, Kume A, Ozawa K.
- Journal Title
  
  Cancer Res
  
  Volume: 73 Pages: 364-372
- Data Source
  KAKENHI-PROJECT-23591548
[Journal Article] CD19 target-engineered T-cells accumulate at tumor lesions in human B-cell lymphoma xenograft mouse models2013
- Author(s)
  Tsukahara T, Ohmine K, Yamamoto C, Uchibori R, Ido H, Teruya T, Urabe M, Mizukami H, Kume A, Nakamura M, Mineno J, Takesako K, Riviere I, Sadelain M, Brentjens R, Ozawa K
- Journal Title
  
  Biochemical and Biophysical Research Communications
  
  Volume: 438 Issue: 1 Pages: 84-89
- DOI
  10.1016/j.bbrc.2013.07.030
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-23591548, KAKENHI-PROJECT-24390247, KAKENHI-PROJECT-24700995, KAKENHI-PROJECT-25430155
[Journal Article] Suppression of lymph node and lung metastases of endometrial cancer by muscle-mediated expression of soluble VEGF receptor-32013
- Author(s)
  Takahashi K, Mizukami H, Saga Y, Takei Y, Urabe M, Kume A, Machida S, Fujiwara H, Suzuki M, Ozawa K.
- Journal Title
  
  Cancer Sci
  
  Volume: 104 Pages: 1107-1111
- Data Source
  KAKENHI-PROJECT-23591548
[Journal Article] An R132H mutation in isocitrate dehydrogenase 1 enhances p21 expression and inhibits phosphorylation of retinoblastoma protein in glioma cells2013
- Author(s)
  Miyata S, Urabe M, Gomi A, Nagai M, Yamaguchi T, Tsukahara T, Mizukami A, Kume A, Ozawa K, Watanabe E.
- Journal Title
  
  Neurol Med Chir (Tokyo)
  
  Volume: 53 Pages: 645-654
- NAID
  10031191634
- Data Source
  KAKENHI-PROJECT-23591548
[Journal Article] Suppression of lymph node and lung metastases of endometrial cancer by muscle-mediated expression of soluble VEGF receptor-32013
- Author(s)
  Takahashi K, Mizukami H, Saga Y, Takei Y, Urabe M, Kume A, Machida S, Fujiwara H, Suzuki M, Ozawa K
- Journal Title
  
  Cancer Science
  
  Volume: 104 Issue: 8 Pages: 1107-1111
- DOI
  10.1111/cas.12184
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-23591548, KAKENHI-PROJECT-24390247, KAKENHI-PROJECT-25462606
[Journal Article] An R132H mutation in isocitrate dehydrogenase 1 enhances p21 expression and inhibits phosphorylation of retinoblastoma protein in glioma cells2013
- Author(s)
  Miyata S, Urabe M, Gomi A, Nagai M, Yamaguchi T, Tsukahara T, Mizukami A, Kume A, Ozawa K, Watanabe E
- Journal Title
  
  Neurologia medico-chirurgica (Tokyo)
  
  Volume: 53 Pages: 645-654
- NAID
  10031191634
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-23591548
[Journal Article] Interleukin-10 expression induced by adeno-associated virus vector suppresses proteinuria in Zucker obese rats2012
- Author(s)
  Ogura M, Urabe M, AkimotoT, Onishi A, Ito T, Tsukahara T, Mizukami H, Kume A, Muto S, Kusano E, Ozawa K.
- Journal Title
  
  Gene Ther
  
  Volume: 19 Pages: 476-482
- Data Source
  KAKENHI-PROJECT-23591548
[Journal Article] Recovery of neurogenic amines in phenylketonuria mice after liver-targeted gene therapy2012
- Author(s)
  Yagi H, Sanechika S, Ichinose H, Sumi-Ichinose C, Mizukami H, Urabe M, Ozawa K, Kume A.
- Journal Title
  
  NeuroReport
  
  Volume: 23 Pages: 30-34
- Data Source
  KAKENHI-PROJECT-23591548
[Journal Article] Interleukin-10 expression induced by adeno-associated virus vector suppresses proteinuria in Zucker obese rats2012
- Author(s)
  Ogura M, Urabe M, Akimoto T, Onishi A, Ito C, Ito T, Tsukahara T, Mizukami H, Kume A, Muto S, Kusano E, and Ozawa K.
- Journal Title
  
  Gene Ther
  
  Volume: 19巻 Issue: 5 Pages: 476-82
- DOI
  10.1038/gt.2011.183
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-21390296, KAKENHI-PROJECT-21591248, KAKENHI-PROJECT-22700923, KAKENHI-PROJECT-23591548, KAKENHI-PROJECT-23659493, KAKENHI-PROJECT-24390247
[Journal Article] Reciprocal upregulation of Notch signaling molecules in hematopoietic progenitor and mesenchymal stromal cells2011
- Author(s)
  Kikuchi Y, Kume A, Urabe M, Mizukami H, Suzuki T, Ozaki K, Nagai T, Ozawa K.
- Journal Title
  
  J Stem Cells Regen Med
  
  Volume: 7 Pages: 61-68
- Data Source
  KAKENHI-PROJECT-23591548
[Journal Article] Complete restoration of phenylalanine oxidation in phenylketonuria mouse by a self-complementary adeno-associated virus vector.2011
- Author(s)
  Yagi H, Ogura T, Mizukami H, Urabe M, Hamada H, Yoshikawa H, Ozawa K, Kume A
- Journal Title
  
  J Gene Med 13
  
  Pages: 114-122
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-20591230
[Journal Article] Reciprocal upregulation of Notch signaling molecules in hematopoietic progenitor and mesenchymal stromal cells2011
- Author(s)
  Kikuchi Y, Kume A, Urabe M, Mizukami H, Suzuki T, Ozaki K, Nagai T, Ozawa K
- Journal Title
  
  Journal of Stem Cells and Regenerative Medicine
  
  Volume: 7 Pages: 61-68
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-23591548
[Journal Article] A phase I study of aromatic L-amino acid decarboxylase gene therapy for Parkinson ' s disease.2010
- Author(s)
  Muramatsu S, Fujimoto K, Kato S, Mizukami H, Asari S, Ikeguchi K, Kawakami T, Urabe M, Kume A, Sato T, Watanabe E, Ozawa K, Nakano I
- Journal Title
  
  Mol Ther 18
  
  Pages: 1731-1735
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-20591230
[Journal Article] Retroviral vector-producing mesenchymal stem cells for targeted suicide cancer gene therapy.2009
- Author(s)
  Uchibori R, Okada T, Ito T, Urabe M, Mizukami H, Kume A, Ozawa K
- Journal Title
  
  J Gene Med 11
  
  Pages: 373-381
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-20591230
[Journal Article] Kinetics and effect of integrin expression on human CD34+ cells during MLV-derived retroviral transduction with a recombinant fibronectin for stem cell gene therapy.2009
- Author(s)
  Horiuchi Y, Onodera M, Miyagawa Y, Sato B, Onda K, Katagiri YU, Okita H, Okada M, Otsu M, Kume A, Okuyama T, Fujimoto J, Kuratsuji T, Kiyakawa N
- Journal Title
  
  Hum Gene Ther 20
  
  Pages: 777-783
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-20591230
[Journal Article] Genomic organization of regions that regulate chicken glycine decarboxylase gene transcription: Physiological and pathological conditions.2009
- Author(s)
  Kawaguchi H, Okamoto S, Sikdar D, Kume A, Li F, Mohafez OM, Shehata MH, Hiraga K
- Journal Title
  
  Gene 432
  
  Pages: 7-18
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-20591230
[Journal Article] Systemic delivery of IL-10 by an AAV-vector presents vascular remodeling and end-organ damage in stroke-prone spontaneously hypertensive rat.2009
- Author(s)
  Nomoto T, Okada T, Shimazaki K, Yoshioka T, Nonaka-Sarukawa M, Ito T, Takeuchi K, Katsura KI, Mizukami H, Kume A, Ookawara S, Ikeda U, Katayama Y, Ozawa K
- Journal Title
  
  Gene Ther 16
  
  Pages: 383-391
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-20591230
[Journal Article] Utility of intraperitoneal administration as a route of AAV serotype 5 vector-mediated neonatal gene transfer.2006
- Author(s)
  Ogura T, Mizukami H, Mimuro J, Okada T, Matsushita T, Urabe M, Kume A, Hamada H, Yoshikawa H, Sakata Y, Ozawa K
- Journal Title
  
  J Gene Med 8(8)
  
  Pages: 990-997
- Description
  「研究成果報告書概要(欧文)」より
- Data Source
  KAKENHI-PROJECT-16390306
[Journal Article] A histone deacetylase inhibitor enhances recombinant adeno-associated virus-mediated gene expression in tumor cells.2006
- Author(s)
  Okada, T., Uchibori, R., Iwata-Okada, M., Takahashi, M., Nomoto, T., Nonaka-Sarukawa, M., Ito, T., Liu, Y., Mizukami, H., Kume, A., Kobayashi, E., Ozawa, K.
- Journal Title
  
  Mol.Ther. 13
  
  Pages: 738-746
- Description
  「研究成果報告書概要(欧文)」より
- Data Source
  KAKENHI-PROJECT-16390281
[Journal Article] Removal of empty capsids from type 1 adeno-associated virus vector stocks by anion-exchange chromatography potentiates transgene expression.2006
- Author(s)
  Urabe, M., Xin, K.Q., Obara, Y., Nakakura, T., Mizukami, H., Kume, A., Okuda, K., Ozawa, K.
- Journal Title
  
  Mol.Ther. 13
  
  Pages: 823-828
- Description
  「研究成果報告書概要(欧文)」より
- Data Source
  KAKENHI-PROJECT-16390281
[Journal Article] Adipose Tissue as a Novel Target for In Vivo Gene Transfer by Using Adeno-Associated Virus Vectors.2006
- Author(s)
  Mizukami H, Mimuro J, Ogura T, Okada T, Urabe M, Kume A, Sakata Y, Ozawa K
- Journal Title
  
  Hum Gene Ther 17(9)
  
  Pages: 921-928
- Description
  「研究成果報告書概要(欧文)」より
- Data Source
  KAKENHI-PROJECT-16390306
[Journal Article] Scalable generation of high-titer recombinant adeno-associated virus type 5 in insect cells.2006
- Author(s)
  Urabe M, Nakakura T, Xin KQ, Obara Y, Mizukami H, Kume A, Kotin RM, Ozawa K.
- Journal Title
  
  J.Virol. 80
  
  Pages: 1874-1885
- Description
  「研究成果報告書概要(欧文)」より
- Data Source
  KAKENHI-PROJECT-16390281
[Journal Article] Large-scale production of recombinant viruses by use of a large culture vessel with active gassing.2005
- Author(s)
  Okada, T., Nomoto, T., Yoshioka, T., Nonaka-Sarukawa, M., Ito, T., Ogura, T., Iwata-Okada, M., Uchibori, R., Shimazaki, K., Mizukami, H., Kume, A., Ozawa, K.
- Journal Title
  
  Hum.Gene Ther. 16
  
  Pages: 1212-1218
- Description
  「研究成果報告書概要(欧文)」より
- Data Source
  KAKENHI-PROJECT-16390281
[Journal Article] Specific and efficient transduction of cochlear inner hair cells with recombinant adeno-associated virus type 3 vector.2005
- Author(s)
  Liu, Y., Okada, T., Sheykholeslami, K., Shimazaki, K., Nomoto, T., Muramatsu, S., Kanazawa, T., Takeuchi, K., Ajalli, R., Mizukami, H., Kume, A., Ichimura, K., Ozawa, K.
- Journal Title
  
  Mol.Ther. 12
  
  Pages: 725-733
- Description
  「研究成果報告書概要(欧文)」より
- Data Source
  KAKENHI-PROJECT-16390281
[Journal Article] High-level in vivo gene marking after gene-modified autologous hematopoietic stem cell transplantation without marrow conditioning in nonhuman primates.2004
- Author(s)
  Ueda K, Hanazono Y, Shibata H, Ageyama N, Ueda Y, Ogata S, Tabata T, Nagashima T, Takatoku M, Kume A, Ikehara S, Taniwaki M, Terao K, Hasegawa M, Ozawa K
- Journal Title
  
  Mol Ther 10(3)
  
  Pages: 469-477
- Description
  「研究成果報告書概要(欧文)」より
- Data Source
  KAKENHI-PROJECT-16390306
[Journal Article] Sustained transgene expression by human cord blood derived CD34(+) cells transduced with simian immunodeficiency virus agmTYO1-based vectors carrying the human coagulation factor VIII gene in NOD/SCID mice.2004
- Author(s)
  Kikuchi, J., Mimuro, J., Ogata, K., Tabata, T., Ueda, Y., Ishiwata, A., Kimura, K., Takano, K., Madoiwa, S., Mizukami, H., Hanazono, Y., Kume, A., Hasegawa, M., Ozawa, K., Sakata, Y.
- Journal Title
  
  J Gene Med. 6
  
  Pages: 1049-1060
- Description
  「研究成果報告書概要(欧文)」より
- Data Source
  KAKENHI-PROJECT-16390281
[Journal Article] Topoisomerase inhibitors enhance the cytocidal effect of AAV-HSVtk/ganciclovir on head and neck cancer cells.2004
- Author(s)
  Kanazawa, T., Mizukami, H., Nishino, H., Okada, T., Hanazono, Y., Kume, A., Kitamura, K., Ichimura, K., Ozawa, K.
- Journal Title
  
  Int.J.Oncol. 25
  
  Pages: 729-735
- Description
  「研究成果報告書概要(欧文)」より
- Data Source
  KAKENHI-PROJECT-16390281
[Journal Article] Expansion of genetically corrected neutrophils in chronic granulomatous disease mice by cotransferring a therapeutic gene and a selective amplifier gene.2004
- Author(s)
  Hara T, Kume A, Hanazono Y, Mizukami H, Okada T, Tsurumi H, Moriwaki H, Ueda Y, Hasegawa M, Ozawa K
- Journal Title
  
  Gene Ther 11(18)
  
  Pages: 1370-1377
- Description
  「研究成果報告書概要(欧文)」より
- Data Source
  KAKENHI-PROJECT-16390306
[Journal Article] Long-term correction of hyperphenylalaninemia by AAV-mediated gene transfer leads to behavioral recovery in phenylketonuria mice.2004
- Author(s)
  Mochizuki S, Mizukami H, Ogura T, Kure S, Ichinohe A, Kojima K, Matsubara Y, Kobayashi E, Okada T, Hoshika A, Ozawa K, Kume A
- Journal Title
  
  Gene Ther 11(13)
  
  Pages: 1081-1086
- Description
  「研究成果報告書概要(欧文)」より
- Data Source
  KAKENHI-PROJECT-16390306
[Journal Article] Adeno-associated virus vector-mediated interleukin-1O gene transfer inhibits atherosclerosis in apoprotein E-deficient mice.2004
- Author(s)
  Yoshioka T, Okada T, Maeda Y, Ikeda U, Shimpo M, Nomoto T, Takeuchi K, Nonaska-Sarukawa M, Ito T, Takahashi T, Mizukami H, Hanazono Y, Kume A, Ookawara S, Kawano M, Ishibashi S, Shimada K, Ozawa K
- Journal Title
  
  Gene Ther 11(24)
  
  Pages: 1772-1779
- Description
  「研究成果報告書概要(欧文)」より
- Data Source
  KAKENHI-PROJECT-16390306
[Journal Article] In vivo expansion of gene-modified hematopoietic cells by a novel selective amplifier gene utilizing the erythropoietin receptor as a molecular switch.2004
- Author(s)
  Nagashima, T., Ueda, Y., Hanazono, Y., Kume, A., Shibata, H., Ageyama, N., Terao, K., Ozawa, K., Hasegawa, M.
- Journal Title
  
  J.Gene Med. 6
  
  Pages: 22-31
- Description
  「研究成果報告書概要(欧文)」より
- Data Source
  KAKENHI-PROJECT-16390281
[Journal Article] Expansion of genetically corrected neutrophils in chronic granulomatous disease mice by cotransferring a therapeutic gene and a selective amplifier gene.2004
- Author(s)
  Hara, T., Kume, A., Hanazono, Y., Mizukami, H., Okada, T., Tsurumi, H., Moriwaki, H., Ueda, Y., Hasegawa, M., Ozawa, K.
- Journal Title
  
  Gene Ther. 11
  
  Pages: 1370-1377
- Description
  「研究成果報告書概要(欧文)」より
- Data Source
  KAKENHI-PROJECT-16390281
[Journal Article] Separate control of Rep and Cap expression utilizing mutant and wild-type loxP sequences and improved packaging system for adeno-associated virus vector production.2004
- Author(s)
  Mizukami, H., Okada, T., Ogasawara, Y., Matsushita, T., Urabe, M., Kume, A., Ozawa, K.
- Journal Title
  
  Mol.Biotechnol. 27
  
  Pages: 7-14
- Description
  「研究成果報告書概要(欧文)」より
- Data Source
  KAKENHI-PROJECT-16390281
[Journal Article] In situ generation of pseudotyped retroviral progeny by adenovirus-mediated transduction of tumor cells enhances the killing effect of HSV-tk suicide gene therapy in vitro and in vivo.2004
- Author(s)
  Okada, T., Caplen, N.J., Ramsey, W.J., Onodera, M., Shimazaki, K., Nomoto, T., Ajalli, R., Wildner, O., Morris, J., Kume, A., Hamada, H., Blaese, R.M., Ozawa, K.
- Journal Title
  
  J.Gene Med. 6
  
  Pages: 288-289
- Description
  「研究成果報告書概要(欧文)」より
- Data Source
  KAKENHI-PROJECT-16390281
[Journal Article] Adeno-associated virus (AAV) vector-mediated liver- and muscle-directed transgene expression using various kinds of promoters and serotypes.2004
- Author(s)
  Mochizuki, S., Mizukami, H., Kume, A., Muramatsu, S., Takeuchi, K., Matsushita, T., Okada, T., Kobayashi, E., Hoshika, A., Ozawa K.
- Journal Title
  
  Gene Ther.Mol.Biol. 8
  
  Pages: 9-18
- Description
  「研究成果報告書概要(欧文)」より
- Data Source
  KAKENHI-PROJECT-16390281
[Journal Article] Long-term correction of hyperphenylalaninemia by AAV-mediated gene transfer leads to behavioral recovery in phenylketonuria mice.2004
- Author(s)
  Mochizuki, S., Mizukami, H., Ogura, T., Kure, S., Ichinohe, A., Kojima, K., Matsubara, Y., Kobayashi, E., Okada, T., Hoshika, A., Ozawa, K., Kume, A.
- Journal Title
  
  Gene Ther. 11
  
  Pages: 1081-1086
- Description
  「研究成果報告書概要(欧文)」より
- Data Source
  KAKENHI-PROJECT-16390281
[Journal Article] High-level in vivo gene marking after gene-modified autologous hematopoietic stem cell transplantation without marrow conditioning in nonhuman primates.2004
- Author(s)
  Ueda, K., Hanazono, Y., Shibata, H., Ageyama, N., Ueda, Y., Ogata, S., Tabata, T., Nagashima, T., Takatoku, M., Kume, A., Ikehara, S., Taniwaki, M., Terao, K., Hasegawa, M., Ozawa, K.
- Journal Title
  
  Mol.Ther. 10
  
  Pages: 469-477
- Description
  「研究成果報告書概要(欧文)」より
- Data Source
  KAKENHI-PROJECT-16390281
[Journal Article] Adeno-associated virus vector-mediated interleukin-10 gene transfer inhibits atherosclerosis in apolipoprotein E-deficient mice.2004
- Author(s)
  Yoshioka, T., Okada, T., Maeda, Y., Ikeda, U., Shimpo, M., Nomoto, T., Takeuchi, K., Nonaka-Sarukawa, M., Ito, T., Takahashi, M., Matsushita, T., Mizukami, H., Hanazono, Y., Kume, A., Ookawara, S., Kawano, M., Ishibashi, S., Shimada, K., Ozawa, K.
- Journal Title
  
  Gene Ther. 11
  
  Pages: 1772-1779
- Description
  「研究成果報告書概要(欧文)」より
- Data Source
  KAKENHI-PROJECT-16390281
[Journal Article] Utility of intraperitoneal administration as a route of AAV serotype 5 vector-mediated neonatal gene transfer.
- Author(s)
  Ogura, T., Mizukami, H., Mimuro, J., Madoiwa, S., Okada, T., Matsushita, T., Urabe, M., Kume, A., Hamada, H., Yoshikawa, H., Sakata, Y., Ozawa, K.
- Journal Title
  
  J.Gene Med. (in press)
- Description
  「研究成果報告書概要(欧文)」より
- Data Source
  KAKENHI-PROJECT-16390281
[Presentation] Adenoassociated virus (AAV) serotype 3-based vector as an alternative vehicle for liver-directed gene therapy2019
- Author(s)
  Kume A, Muramatsu S, Mizukami H, Onmori T
- Organizer
  European Society of Gene and Cell Therapy
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-18K07853
[Presentation] Tumor targeting using CD19-specific CAR (chimeric antigen receptor) for B-cell lymphoma2013
- Author(s)
  Tsukahara T, Ohmine K, Uchibori R, Ido H, Urabe M, Mizukami H, Kume A, Nakamura M, Mineno J, Takesako K, Riviere I, Sadelain M, Brentjens R, Ozawa K.
- Organizer
  American Society of Gene and Cell Therapy 16th Annual Meeting
- Place of Presentation
  Salt Lake City, UT, USA
- Year and Date
  2013-05-18
- Data Source
  KAKENHI-PROJECT-23591548
[Presentation] Accurate measurement of Nab status against AAV vector capsids and an approach toward managing its inhibitory effect2013
- Author(s)
  Mizukami H, Mimuro J, Hishikawa S, Ikemoto T, Uchibori R, Tsukahara T, Urabe M, Kume A, Sakata A, Ohmori T, Madoiwa S, Sakata Y, Ozawa K.
- Organizer
  European Society of Gene and Cell Therapy and French Society for Cell and Gene Therapy Collaborative Congress 2013
- Place of Presentation
  Madrid, Spain
- Year and Date
  2013-10-25
- Data Source
  KAKENHI-PROJECT-23591548
[Presentation] Precise evaluation of Nab status against adeno-associated viral vectors and an approach toward managing its inhibitory effect2013
- Author(s)
  Mizukami H, Mimuro J, Hishikawa S, Ikemoto T, Uchibori R, Tsukahara T, Urabe M, Kume A, Sakata A, Ohmori T, Madoiwa S, Sakata Y, Ozawa K.
- Organizer
  American Society of Gene and Cell Therapy 16th Annual Meeting
- Place of Presentation
  Salt Lake City, UT, USA
- Year and Date
  2013-05-16
- Data Source
  KAKENHI-PROJECT-23591548
[Presentation] Evaluation of anti-tumor effevts mediated by engineered T lymphocytes expressing a CD19 specific CAR for B cell lymphoma2012
- Author(s)
  Tsukahara T, Ohmine K, Uchibori R, Ido H, Urabe M, Mizukami H, Kume A, Nakamura M, Riviere I, Sadelain M, Brentjens R, Ozawa K.
- Organizer
  American Society of Gene and Cell Therapy
- Place of Presentation
  Philadelphia, PA, USA
- Year and Date
  2012-05-19
- Data Source
  KAKENHI-PROJECT-23591548
[Presentation] Evaluation of anti-tumor effevts mediated by engineered T lymphocytes expressing a CD19 specific CAR for B cell lymphoma.2012
- Author(s)
  Tsukahara T, Ohmine K, Uchibori R, Ido H, Urabe M, Mizukami H, Kume A, Nakamura M, Riviere I, Sadelain M, Brentjens R, Ozawa K
- Organizer
  American Society of Gene and Cell Therapy
- Place of Presentation
  Philadelphia, PA, USA
- Data Source
  KAKENHI-PROJECT-23591548
[Presentation] Gene threrapy for phenylketonuria2011
- Author(s)
  Kume A
- Organizer
  Japan Society of Gene Therapy 17th Annual Meeting(招待講演)
- Place of Presentation
  福岡
- Data Source
  KAKENHI-PROJECT-23591548
[Presentation] Muscle-directed gene therapy for phenylketonuria with self-complementary AAV vectors2011
- Author(s)
  Kume A, Yagi H, Mizukami H, Urabe M, Tsukahara T, Uchibori R, Ozawa K.
- Organizer
  XIXth Annual Congress of European Society of Gene and Cell Therapy
- Place of Presentation
  Brighton, UK
- Year and Date
  2011-10-28
- Data Source
  KAKENHI-PROJECT-23591548
[Presentation] Gene threrapy for phenylketonuria. Japan Society of Gene Therapy2011
- Author(s)
  Kume A.
- Organizer
  17th Annual Meeting
- Place of Presentation
  Fukuoka(Invited)
- Year and Date
  2011-07-17
- Data Source
  KAKENHI-PROJECT-23591548
[Presentation] Promoter selection for AAV vector-mediated factor IX expression in skeletal muscle2010
- Author(s)
  Kume A, et al.
- Organizer
  The 13th Annual Meeting of the American Society of Gene and Cell Therapy
- Place of Presentation
  Washington DC, USA
- Year and Date
  2010-05-21
- Data Source
  KAKENHI-PROJECT-20591230
[Presentation] Choice of small-sized prpmoter for AAV-mediated factor IX expression in skeletal muscle.2010
- Author(s)
  Kume A, Yagi H, Mizukami H, Urabe M, Tsukahara T, Ishiwata A, mimuro J, Madoiwa S, Ohmori T, Sakata Y, Ozawa K
- Organizer
  第16回日本遺伝子治療学会
- Place of Presentation
  宇都宮
- Year and Date
  2010-07-01
- Data Source
  KAKENHI-PROJECT-20591230
[Presentation] 筋組織を標的とするAAV ベクターを用いた「フェニルケトン尿症」に対する新生仔遺伝子治療の長期的効果2009
- Author(s)
  小倉剛、水上浩明、八木洋也、濱田洋実、吉川裕之、小澤敬也、久米晃啓
- Organizer
  第61回日本産婦人科学会学術講演会
- Place of Presentation
  京都
- Year and Date
  2009-04-05
- Data Source
  KAKENHI-PROJECT-20591230
[Presentation] Liver-targeted gene therapy with a self-complementary AAV ameliorates brain aminergic deficit in phenylketonuria mice2009
- Author(s)
  Kume A, et al
- Organizer
  XVIIth Annual Congress of the European Society of Gene and Cell Therapy
- Place of Presentation
  Hannover, Germany
- Year and Date
  2009-11-22
- Data Source
  KAKENHI-PROJECT-20591230
[Presentation] Kinetics and defect of integrin expression on human CD34+ cells during MLV-derived retroviral transduction with a recombinant fibronectin for stem cell gene therapy.2009
- Author(s)
  Horiuchi Y, Onodera M, Miyagawa Y, Sato B, Onda K, Katagiri YU, Okita H, Okada M, Otsu M, Kume A, Okuyaka T, Fujimoto J, Kuratsuji T, Kiyokawa N
- Organizer
  第15回日本遺伝子治療学会
- Place of Presentation
  吹田
- Year and Date
  2009-07-11
- Data Source
  KAKENHI-PROJECT-20591230
[Presentation] liver-targeted gene therapy with a self-complementary AAV ameliorated brain aminergic deficit in phenylketonuria mice.2009
- Author(s)
  Yagi H, Sanechika S, Ichinose H, Mizukami H, Ogura T, Urabe M, Hamada H, Yoshikawa K, Ozawa K, Kume A
- Organizer
  第15回日本遺伝子治療学会
- Place of Presentation
  吹田
- Year and Date
  2009-07-11
- Data Source
  KAKENHI-PROJECT-20591230
[Presentation] Promoter selection for muscle-directed self-complementary AAV toward hemophilia B gene thearapy.2009
- Author(s)
  Kume A, Yagi H, Mizukami H, Urabe M, Tsukahara T, Ishiwata A, Mimuro J, Madoiwa S, Ohmori T, Sakata Y, Ozawa K
- Organizer
  第71回日本血液学会学術集会
- Place of Presentation
  京都
- Year and Date
  2009-10-23
- Data Source
  KAKENHI-PROJECT-20591230
[Presentation] Promoter selection for AAV vector-mediated factor IX expression in skeletal muscle.2009
- Author(s)
  Kume A, Yagi H, Mizukami H, Urabe M, Tsukahara T, Ishiwata A, Mimuro J, Madoiwa S, Ohmori T, Sakata Y, Ozawa K
- Organizer
  American Society of Gene Therapy's 13th Annual Meeting
- Place of Presentation
  Washington, DC, USA
- Year and Date
  2009-05-21
- Data Source
  KAKENHI-PROJECT-20591230
[Presentation] Improvement of monoamine metabolism in phenylketonuria mouse brain treated with a self-complementary adeno-associated vector.2009
- Author(s)
  Yagi H, Sanechika S, Ichinose H, Mizukami H, Ogura T, Urabe M, Hamada H, Yoshikawa H, Ozawa K, Kume A
- Organizer
  American Society of Gene Therapy's 12th Annual Meeting
- Place of Presentation
  San Diego, CA, USA
- Year and Date
  2009-05-27
- Data Source
  KAKENHI-PROJECT-20591230
[Presentation] 自己相補型アデノ随伴ウイルスベクターによるフェニルケトン尿症の遺伝子治療 ? maternal PKUの予防に向けて2009
- Author(s)
  八木洋也、水上浩明、小倉剛、濱田洋実、吉川裕之、小澤敬也、久米晃啓
- Organizer
  第61回日本産婦人科学会学術講演会
- Place of Presentation
  京都
- Year and Date
  2009-04-05
- Data Source
  KAKENHI-PROJECT-20591230
[Presentation] 改良型アデノ随伴ウイルスベクターによるフェニルケトン尿症遺伝子治療2009
- Author(s)
  久米晃啓、八木洋也、小倉剛、水上浩明、卜部匡司、小澤敬也
- Organizer
  第112回日本小児科学会小児科学会学術集会
- Place of Presentation
  奈良
- Year and Date
  2009-04-18
- Data Source
  KAKENHI-PROJECT-20591230
[Presentation] Liver-targeted gene therapy with a self-complementary AAV ameliorates brain aminergic deficit in phenylketonuria mice.2009
- Author(s)
  Kume A, Yagi H, Sanechika S, Ichinose H, Mizukami H, Urabe M, Ozawa K
- Organizer
  XVIIth Annual Congress of the European Society of Gene and Cell Therapy
- Place of Presentation
  Hannover, Germ any
- Year and Date
  2009-11-22
- Data Source
  KAKENHI-PROJECT-20591230
[Presentation] Complete retoration of in vivo oxidative capacity for phenylalanine in self-complementary AAV vector-treated phenylketonuria mice.2008
- Author(s)
  Kume A., et al
- Organizer
  American Society of Gene Therapy 11th Annual Meeting
- Place of Presentation
  Boston, MA, USA
- Year and Date
  2008-05-31
- Data Source
  KAKENHI-PROJECT-20591230
[Presentation] Efficient and stable liver transduction by a self-complementary adeno-associated virus vector for phenylketonuria gene therapy.2007
- Author(s)
  Kume A et al
- Organizer
  Japan Society of Gene Therapy
- Place of Presentation
  Nagoya
- Year and Date
  2007-06-28
- Data Source
  KAKENHI-PROJECT-18015044
[Presentation] Long-term efficacy of a self-complementary adeno-associated virus vector for phenylketonuria gene therapy.2007
- Author(s)
  Kume A et al
- Organizer
  American Society of Gene Therapy
- Place of Presentation
  Seattle, WA, USA
- Year and Date
  2007-05-31
- Data Source
  KAKENHI-PROJECT-18015044

1. OZAWA Keiya (30137707)

# of Collaborated Projects: 14 results

# of Collaborated Products: 23 results
2. URABE Masashi (40213516)

# of Collaborated Projects: 6 results

# of Collaborated Products: 1 results
3. MIZUKAMI Hiroaki (20311938)

# of Collaborated Projects: 5 results

# of Collaborated Products: 13 results
4. HASEGAWA Mamoru

# of Collaborated Projects: 2 results

# of Collaborated Products: 0 results
5. TAKAHASHI Naoto (50197159)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
6. UEHARA Ritei (90276999)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
7. IMANISHI Kenichi (20132920)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
8. KUSUDA Satoshi (50372983)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
9. SUZUMURA Hiroshi (50216470)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
10. ONODERA Masafumi (10334062)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
11. HANAZONO Yutaka (70251246)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
12. OKADA Takashi (00326828)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
13. MATSUSITA Takashi (20343444)

# of Collaborated Projects: 1 results

# of Collaborated Products: 4 results
14. 間野博行 (90240704)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
15. TSUCHIDA Shinya

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
16. NISHIMURA Riki

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
17. WATABE Hiroyuki

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
18. KONO Yumi

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
19. KOIKE Yasunori

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
20. YADA Yukari

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
21. MATANO Miyuki

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
22. SUZUKI Yume

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
23. TAKAHASHI Kayo

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
24. SAKATA Tsuneaki

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
25. TAKAHASHI Tohru

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
26. 真下知士

# of Collaborated Projects: 0 results

# of Collaborated Products: 1 results

Kume Akihiro 久米 晃啓

久米 晃啓 クメ アキヒロ

KUME Akihiro 久米 晃啓

Research Projects

Research Products

Co-Researchers

Establishment of virus-free cell substrates for protein drug productionPrincipal Investigator

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Genome instability caused by EVI1 oncogene activationPrincipal Investigator

Principal Investigator

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Principal Investigator

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Extrahepatic tissue-targeted gene therapy for phenylketonuriaPrincipal Investigator

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新規クロマチンインシュレータを搭載した遺伝子治療ベクターの開発Principal Investigator

Principal Investigator

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Review Section

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新生児期遺伝子治療におけるアデノ随伴ウイルスベクターの体内動態と治療効果Principal Investigator

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Gene therapy for chronic granulomatous disease in combination with selective cell amplification and utilizing hematopoietic microenvironmentPrincipal Investigator

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キメラ受容体遺伝子導入による白血病細胞療法の効果増強Principal Investigator

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Gene therapy for chronic granulomatous disease combined with in vivo expansion of transduced hematopoietic cells.Principal Investigator

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AAVベクターによる抗腫瘍血管療法と新規アデノ-AAVハイブリッドベクターの開発Principal Investigator

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Kume Akihiro 久米晃啓

久米晃啓クメアキヒロ

KUME Akihiro 久米晃啓