OZAKI Katsutoshi 尾崎勝俊

… Alternative Names

尾崎勝俊オザキカツトシ

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Researcher Number	10286453
Other IDs
Affiliation (Current)	2025: 日本医科大学, 医学部, 教授
Affiliation (based on the past Project Information) *help	2007 – 2011: Jichi Medical University, 医学部, 講師 2006: 自治医大, 医学部, 講師 2005: 東大, 医科学研究所
Review Section/Research Field	Principal Investigator Hematology Except Principal Investigator Hematology
Keywords	Principal Investigator GVHD / IL-21 / 血液免疫学 / Th2 / Th1 / 移植後合併症 / サイトカイン / 制御性T細胞 / GVL / 免疫制御 … More Except Principal Investigator … More 可溶型TRAIL / 細胞治療 / 遺伝子導入 / 抗腫瘍性サイトカイン / 遺伝子治療 / 腫瘍集積性 / 間葉系幹細胞 / 悪性リンパ腫 Less

Mechanisms for the attenuated GVHD by blocking IL-21Principal Investigator
- Principal Investigator
  
  OZAKI Katsutoshi
- Project Period (FY)
  2009 – 2011
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Research Field
  
  Hematology
- Research Institution
  Jichi Medical University
Development of gene therapy for malignant lymphoma using mesenchymal stem cells with tumor-accumulating capacity
- Principal Investigator
  
  OZAWA Keiya
- Project Period (FY)
  2007 – 2008
- Research Category
  
  Grant-in-Aid for Scientific Research (B)
- Research Field
  
  Hematology
- Research Institution
  Jichi Medical University
Decoy receptor for IL-21 ameliorates GVHDPrincipal Investigator
- Principal Investigator
  
  OZAKI Katsutoshi
- Project Period (FY)
  2007 – 2008
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Research Field
  
  Hematology
- Research Institution
  Jichi Medical University
GVHD,GVLにおけるIL-21の投割Principal Investigator
- Principal Investigator
  
  尾崎勝俊
- Project Period (FY)
  2005 – 2006
- Research Category
  
  Grant-in-Aid for Young Scientists (B)
- Research Field
  
  Hematology
- Research Institution
  Jichi Medical University
  The University of Tokyo

All 2011 2010 2009 2008 2007 Other

All Journal Article Presentation

[Journal Article] Regulato ry T cells and IL-17-producing cells in graft-versus-host disease2011
- Author(s)
  Teshima T, Maeda Y, Ozaki K
- Journal Title
  
  Immunot herapy
  
  Volume: 3(7) Pages: 833-52
- Data Source
  KAKENHI-PROJECT-21591247
[Journal Article] Mesenchymal s tem cells inhibit Th17 but not regula tory T cell differentiation2011
- Author(s)
  Tatara, R., Ozaki, K., Kikuchi Y., Ha tanaka, K., Oh, I., Meguro, A., Matsu, H., Sato, K. Ozawa, K
- Journal Title
  
  Cytotherapy
  
  Volume: 13(6) Pages: 686-694
- Data Source
  KAKENHI-PROJECT-21591247
[Journal Article] Lack of IL-21 signal attenu ates graft-versus-leukemia effect in the absence of CD8 T-cells2011
- Author(s)
  Meguro A, Ozaki K, Hatanaka K, Oh I, Sudo K, Ohmori T, Matsu H, Tatara R, Sato K, Sakata Y, Nakae S, Leonard WJ, Ozawa K
- Journal Title
  
  Bone Marrow Transplant
  
  Volume: 46(12) Pages: 1557-1565
- Data Source
  KAKENHI-PROJECT-21591247
[Journal Article] Altered effec tor CD4+T cell function in IL-21R-/-CD4+T cell-mediated graft-versus-ho st disease2010
- Author(s)
  Oh I, Ozaki K, Meguro A, Hatanaka K, Kadowaki M, Matsu H, Tatara R, Sato K, Iwakura Y, Nakae S, Sudo K, Teshima T, Leonard WJ, Ozawa K
- Journal Title
  
  J Immunol
  
  Volume: 185(3) Pages: 1920-1926
- Data Source
  KAKENHI-PROJECT-21591247
[Journal Article] IL-21 is critical for graft-versus-host disease in a mouse model2010
- Author(s)
  Meguro A, Ozaki K, Oh I, Hatanaka K, Matsu H, Tatara R, Sato K, Leonard WJ, Ozawa K
- Journal Title
  
  Bone Marrow Transplant
  
  Volume: 45(4) Pages: 723-9
- Data Source
  KAKENHI-PROJECT-21591247
[Journal Article] Bortezomib overcomes cell adhesion-mediated drug resistance through downregulation of VLA-4 expression in multiple myeloma2009
- Author(s)
  Noborio-Hatano K, Kikuchi J, Takatoku M, Shimizu R, Wada T, Ueda M, Nobuyoshi M, Oh I, Sato K, Suzuki T, Ozaki K, Mori M, Nagai T, Muroi K, Kano Y, Furukawa Y, Ozawa K
- Journal Title
  
  Oncogene 28(2)
  
  Pages: 231-242
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-19591131
[Journal Article] Prediction of response to imatinib in patients with chronic myelogenous leukemia by flow cytometric analysis of bone marrow blastic cell phenotypes.2009
- Author(s)
  Oka S, Muroi K, Mori M, Matsuyama T, Fujiwara S, Oh I, Sato K, Kikuchi S, Ueda M, Toshima M, Suzuki T, Ozaki K, Nagai T, Ozawa K
- Journal Title
  
  Leuk Lymphoma 50(2)
  
  Pages: 290-293
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-19591131
[Journal Article] Bortezomib overcomes cell adhesion-mediated drug resistance through downregulation of VLA-4 expression in multiple myeloma.2009
- Author(s)
  Hatano, K., Kikuchi, J., Takatoku, M., Shimizu, R., Wada, T., Ueda, M., Nobuyoshi, M., Oh, I., Sato, K., Suzuki, T., Ozaki, K., Mori, M., Nagai, T., Muroi, K., Kano, Y,. Furukawa, Y., and Ozawa, K.
- Journal Title
  
  Oncogene 28(2)
  
  Pages: 231-242
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-19390267
[Journal Article] Prediction of response t o imatinib in patients with chronic mye logenous leukemia by flow cytometric an alysis of bone marrow blastic cell phen otypes2009
- Author(s)
  Oka S, Muroi K, Mori M, Matsuyama T, Fujiwara S, Oh I, Sato K, Kikuchi S, Ue da M, Toshima M, Suzuki T, Ozaki K, Nagai T, Ozawa K
- Journal Title
  
  Leuk Lymphoma. 50(2)
  
  Pages: 290-29
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-19591131
[Journal Article] Bortezomib overcomes cell adhesion-mediated drug resistance through downregulation of VLA-4 expression in multiple myeloma.2008
- Author(s)
  Noborio-Hatano K, Kikuchi J, Takatoku M, Shimizu R, Wada T, Ueda M, Nobuyoshi M, Oh I, Sato K, Suzuki T, Ozaki K, Mori M, Nagai T, Muroi K, Kano Y, Furukawa Y, Ozawa K
- Journal Title
  
  Oncogene. 28(2)
  
  Pages: 231-242
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-19591131
[Journal Article] Cell and gene therapy using mesenchymal stem cells (MSCs).2008
- Author(s)
  Ozawa, K., Sato, K., Oh, I., Ozaki, K., Uchibori, R., Obara, Y., Kikuchi, Y., Ito, T., Okada, T., Urabe, M., Mizukami, H., and Kume, A.
- Journal Title
  
  J. Autoimmun. 30(3)
  
  Pages: 121-127
- Data Source
  KAKENHI-PROJECT-19390267
[Journal Article] Cell and gene therapy using mesenchymal stem cells (MSCs).2008
- Author(s)
  Ozawa, K., Sato, K., Oh, I., Ozaki, K,. Uchibori, R., Obara, Y., Kikuchi, Y., Ito, T.,Okada, T., Urabe, M., Mizukami, H., and Kume, A.
- Journal Title
  
  J. Autoimmun. 30(3)
  
  Pages: 121-127
- Data Source
  KAKENHI-PROJECT-19390267
[Journal Article] Cell and gene therapy using mesenchymal stem cells (MSCs).2008
- Author(s)
  Ozawa K, Sato K, Oh I, Ozaki K, Uchibori R, Obara Y, Kikuchi Y, Ito T, Okada T, Urabe M, Mizukami H, Kume A
- Journal Title
  
  J Autoimmun. 30(3)
  
  Pages: 121-127
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-19591131
[Journal Article] Mechanisms of immunomodulation by mesenchymal stem cells.2007
- Author(s)
  Ozaki, K.
- Journal Title
  
  Int. J. Hematol. 86
  
  Pages: 5-7
- NAID
  40015594590
- Data Source
  KAKENHI-PROJECT-19390267
[Journal Article] Screening of genes responsible for differentiation of mouse mesenchymal stromal cells by DNA micro-array analysis of C3H10T1/2 and C3H10T1/2-derived cell lines.2007
- Author(s)
  Oh I, Ozaki K, Miyazato A, Sato K, Meguro A, Muroi K, Nagai T, Mano H, Ozawa K
- Journal Title
  
  Cytotherapy 9
  
  Pages: 80-90
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-19591131
[Journal Article] Interferon-gamma and NF-kappaB mediate nitric oxide production by mesenchymal stromal cells.2007
- Author(s)
  Oh I, Ozaki K, Sato K, Meguro A, Tatara R, Hatanaka K, Nagai T, Muroi K, Ozawa K
- Journal Title
  
  Biochem Biophys Res Commun 355
  
  Pages: 956-962
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-19591131
[Journal Article] Interferon-gamma and NF-kappaB mediate nitric oxide production by mesenchymal stromal cells.2007
- Author(s)
  Oh, T., Ozaki, K., Sato, K., Meguro, A., Tatara, R., Hatanaka, K., Nagai, T., Muroi, K., Ozawa, K.
- Journal Title
  
  Biochem. Biophys. Res. Commun. 355
  
  Pages: 956-962
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-19390267
[Journal Article] Mechanisms of immunomodulation by mesenchymal stem cells.2007
- Author(s)
  Ozaki, K., Sato, K., Oh, I., Meguro, A., Tatara, R., Muroi, K., and Ozawa, K.
- Journal Title
  
  Int. J. Hematol. 86
  
  Pages: 5-7
- NAID
  10018515331
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-19390267
[Journal Article] Nitric oxide plays a critical role in suppression of T cell proliferation by mesenchy mal stem cells.2007
- Author(s)
  Sato K, Ozaki K, Oh I, Meguro A, Hatanaka K, Nagai T, Muroi K, Ozawa K
- Journal Title
  
  Blood 109
  
  Pages: 228-234
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-19591131
[Journal Article] Screening of genes responsible for differentiation of mouse mesenchymal stromal cells by DNA microarray analysis of C3H10T1/2 and C3H10T1/2 -derived cell lines.2007
- Author(s)
  Oh, I., Ozaki, K., Miyazato, A., Sato, K., Meguro, A., Muroi, K., N agai, T., Mano, H., and Ozawa, K.
- Journal Title
  
  Cytotherapy 9
  
  Pages: 80-90
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-19390267
[Journal Article] A Lower Starting Dose of Eltrombo pag is Efficacious in Japanese Patien ts with Previously Treated Chronic Im mune Thrombocytopenia(ITP)
- Author(s)
  Tomiyama Y, Miyakawa Y, Okamato S, Ka tsutani S, Kimura A, Okoshi Y, Ninomi ya H, Kosugi H, Nomura S, Ozaki K, Ik eda Y, Hattori T, Katsura K, Kanakura Y
- Journal Title
  
  J. Throm b. & Hemost
  
  Volume: (in press)
- Data Source
  KAKENHI-PROJECT-21591247
[Presentation] Stat3 is critical for GVHD2011
- Author(s)
  尾崎勝俊
- Organizer
  第52回米国血液学会
- Place of Presentation
  San Diego
- Year and Date
  2011-12-10
- Data Source
  KAKENHI-PROJECT-21591247
[Presentation] Stat3 activation in donor CD4 T-cells is critical for acute GVHD2011
- Author(s)
  Ozaki K, Matsu H, Hatanaka K, Meguro A, Oh I, Tatara R, Suzuki T, Mori M, Muroi K, Nagai T, Ozawa K
- Organizer
  2011 Annual Meeting of ASH at San Diego
- Data Source
  KAKENHI-PROJECT-21591247
[Presentation] Mesenchymal stem cell mediated suppression of Th17 differentiation through PGE2 and IDO production2010
- Author(s)
  Tatara R, Ozaki K, Kikuchi Y, Hatanaka K, Oh I, Meguro A, Matsu H, Sato K, Nagai T, Muroi K, Ozawa K
- Organizer
  第72回日本血液学会学術集会
- Place of Presentation
  横浜
- Data Source
  KAKENHI-PROJECT-21591247
[Presentation] Lack of IL-21 signal attenuates graft-versus-leukemia effect in the absence of CD8 T-cells.2010
- Author(s)
  Ozaki K
- Organizer
  52th ASH Annual Meeting
- Place of Presentation
  Orlando, FL, USA
- Data Source
  KAKENHI-PROJECT-21591247
[Presentation] 移植片対宿主病におけるSTAT3の役割に関する発生工学的手法を用いた検討2010
- Author(s)
  松春子、尾崎勝俊、畑中恵子、多々良礼音、目黒明子、翁家国、佐藤一也、鈴木隆浩、森政樹、永井正、室井一男、永井正、植松智、審良静男、小澤敬也
- Organizer
  第72回日本血液学会学術集会
- Place of Presentation
  横浜
- Data Source
  KAKENHI-PROJECT-21591247
[Presentation] IL-21のシグナル抑制とgraft-versus-leukemia効果2010
- Author(s)
  目黒明子、尾崎勝俊、畑中恵子、翁家国、松春子、多々良礼音、佐藤一也、大嶺謙、鈴木隆浩、森政樹、永井正、室井一男、須藤カツ子、中江進、小澤敬也
- Organizer
  第72回日本血液学会学術集会
- Place of Presentation
  横浜
- Data Source
  KAKENHI-PROJECT-21591247
[Presentation] Blocking of IL-21 signal attenuates graft-versus-host disease but not graft-versus-leukemia effect in a mouse model2009
- Author(s)
  Meguro A, Ozaki K, Oh I, Matsu H, Hatanaka K, Sato K, Tatara R, Suzuki T, Mori M, Nagai T, Muroi K, Ozawa K
- Organizer
  第67回日本癌学会学術総会
- Place of Presentation
  名古屋
- Data Source
  KAKENHI-PROJECT-21591247
[Presentation] CD4陽性T細胞の移植によって誘導されるGVHDとIL-21の重要性2009
- Author(s)
  翁家国, 尾崎勝俊, 目黒明子, 畑中恵子, 多々良礼音, 松春子, 佐藤一也, 永井正, 室井一男, 小澤敬也
- Organizer
  第71回日本血液学会学術集会
- Place of Presentation
  京都
- Data Source
  KAKENHI-PROJECT-21591247
[Presentation] 間葉系幹細胞がTh17、Treg分化に及ぼす影響2009
- Author(s)
  多々良礼音, 尾崎勝俊, 畑中恵子, 翁家国, 松春子, 目黒明子, 佐藤一也, 永井正, 室井一男, 小澤敬也
- Organizer
  第71回日本血液学会学術集会
- Place of Presentation
  京都
- Data Source
  KAKENHI-PROJECT-21591247
[Presentation] Mesenchymal stem cells inhibit Th17 differentiation through PGE2 production2009
- Author(s)
  Tatara R, Ozaki K, Oh I, Hatanaka K, Meguro A, Matsu H, Sato K, Nagai T, Muroi K, Ozawa K
- Organizer
  2009 Annual Meeting of ASH at New Orleans
- Data Source
  KAKENHI-PROJECT-21591247
[Presentation] Blocking of IL-21 signal attenuates graft-versus-host disease but not graft-versus-leukemia effect in a mouse model.2008
- Author(s)
  Meguro A, Ozaki K, Oh I, Matsu H, Hatanaka K, Sato K, Tatara R, Suzuki T, Mori M, Nagai T, Muroi K, Ozawa K
- Organizer
  第67 回日本癌学会学術総会(O-181, Program p87)
- Place of Presentation
  名古屋
- Year and Date
  2008-10-28
- Data Source
  KAKENHI-PROJECT-19591131
[Presentation] Blocking of IL-21 signal attenuates graft-versus-host disease but not graft-versus-leukemia effect in a mouse model.2008
- Author(s)
  Meguro A, Ozaki K, Oh I, Matsu H, Hatanaka K, Tatara R, Leonard WJ, Sato K, Ozawa K
- Organizer
  2008 Annual Meeting of ASH at San Francisco, CA
- Place of Presentation
  Moscone Center
- Year and Date
  2008-12-06
- Data Source
  KAKENHI-PROJECT-19591131
[Presentation] Blocking of IL-21 signal attenuates graft-versus-host disease but not graft-versus-leukemia effect in a mouse model.2008
- Author(s)
  Meguro A, Ozaki K, Oh I, Matsu H, Hatanaka K, Tatara R, Leonard WJ, Sato K, Ozawa K
- Organizer
  2008 Annual Meeting of ASH(Blood 2008;112(11): 453a)
- Place of Presentation
  San Francisco, CA,
- Year and Date
  2008-12-07
- Data Source
  KAKENHI-PROJECT-19591131
[Presentation] Blocking of IL-21 signal attenuates graft-versus-host disease but not graft-versus-leukemia effect in a mouse model.2008
- Author(s)
  Meguro A, Ozaki K, Oh I, Matsu H, Hatanaka K, Sato K, Tatara R, Suzuki T, Mori M, Nagai T, Muroi K, Ozawa K
- Organizer
  第67回日本癌学会学術総会
- Place of Presentation
  名古屋国際会議場
- Year and Date
  2008-10-28
- Data Source
  KAKENHI-PROJECT-19591131
[Presentation] GVHDにおけるIL-21の役割2007
- Author(s)
  目黒明子, 尾崎勝俊, 翁家国, 佐藤一也, 多々良礼音, 松春子, 畑中恵子, 鈴木隆浩, 森政樹, 永井正, 室井一男, 小澤敬也
- Organizer
  日本血液学会日本臨床血液学会合同総会
- Place of Presentation
  横浜
- Year and Date
  2007-10-11
- Data Source
  KAKENHI-PROJECT-19591131

1. OZAWA Keiya (30137707)

# of Collaborated Projects: 1 results

# of Collaborated Products: 6 results

OZAKI Katsutoshi 尾崎 勝俊

尾崎 勝俊 オザキ カツトシ

Research Projects

Research Products

Co-Researchers

Mechanisms for the attenuated GVHD by blocking IL-21Principal Investigator

Principal Investigator

Project Period (FY)

Research Category

Research Field

Research Institution

Development of gene therapy for malignant lymphoma using mesenchymal stem cells with tumor-accumulating capacity

Principal Investigator

Project Period (FY)

Research Category

Research Field

Research Institution

Decoy receptor for IL-21 ameliorates GVHDPrincipal Investigator

Principal Investigator

Project Period (FY)

Research Category

Research Field

Research Institution

GVHD,GVLにおけるIL-21の投割Principal Investigator

Principal Investigator

Project Period (FY)

Research Category

Research Field

Research Institution

[Journal Article] Regulato ry T cells and IL-17-producing cells in graft-versus-host disease2011

Author(s)

Journal Title

Data Source

[Journal Article] Mesenchymal s tem cells inhibit Th17 but not regula tory T cell differentiation2011

Author(s)

Journal Title

Data Source

[Journal Article] Lack of IL-21 signal attenu ates graft-versus-leukemia effect in the absence of CD8 T-cells2011

Author(s)

Journal Title

Data Source

[Journal Article] Altered effec tor CD4+T cell function in IL-21R-/-CD4+T cell-mediated graft-versus-ho st disease2010

Author(s)

Journal Title

Data Source

[Journal Article] IL-21 is critical for graft-versus-host disease in a mouse model2010

Author(s)

Journal Title

Data Source

[Journal Article] Bortezomib overcomes cell adhesion-mediated drug resistance through downregulation of VLA-4 expression in multiple myeloma2009

Author(s)

Journal Title

Data Source

[Journal Article] Prediction of response to imatinib in patients with chronic myelogenous leukemia by flow cytometric analysis of bone marrow blastic cell phenotypes.2009

Author(s)

Journal Title

Data Source

[Journal Article] Bortezomib overcomes cell adhesion-mediated drug resistance through downregulation of VLA-4 expression in multiple myeloma.2009

Author(s)

Journal Title

Data Source

[Journal Article] Prediction of response t o imatinib in patients with chronic mye logenous leukemia by flow cytometric an alysis of bone marrow blastic cell phen otypes2009

Author(s)

Journal Title

Data Source

[Journal Article] Bortezomib overcomes cell adhesion-mediated drug resistance through downregulation of VLA-4 expression in multiple myeloma.2008

Author(s)

Journal Title

Data Source

[Journal Article] Cell and gene therapy using mesenchymal stem cells (MSCs).2008

Author(s)

Journal Title

Data Source

[Journal Article] Cell and gene therapy using mesenchymal stem cells (MSCs).2008

Author(s)

Journal Title

Data Source

[Journal Article] Cell and gene therapy using mesenchymal stem cells (MSCs).2008

Author(s)

Journal Title

OZAKI Katsutoshi 尾崎勝俊

尾崎勝俊オザキカツトシ