TSUCHIHASHI Takatoshi 土橋隆俊

Researcher Number	10286528
Other IDs
Affiliation (based on the past Project Information) *help	2020 – 2021: 慶應義塾大学, 医学部(信濃町), 客員講師 2017 – 2019: 慶應義塾大学, 医学部(信濃町), 共同研究員 2016: 慶應義塾大学, 医学部(信濃町), 医師(非常勤) 2015: 慶應義塾大学, 医学部, その他 2015: 慶應義塾大学, 医学部, 共同研究員 2014: 慶應義塾大学, 医学部, 研究員 2010 – 2013: 慶應義塾大学, 医学部, 共同研究員
Review Section/Research Field	Except Principal Investigator Pediatrics / Basic Section 52050:Embryonic medicine and pediatrics-related
Keywords	Except Principal Investigator 遺伝子 / 循環器・高血圧 / 発現制御 / 発生・分化 / シグナル伝達 / 先天性心疾患 / 小児循環器学 / 二次心臓領域 / 心臓神経堤細胞 / Tbx20 … More / Tbx1 / TBX1 / 総動脈幹症 / 多因子遺伝 / 循環器 / レチノイン酸 / 大動脈弓発生 / Ｔｂｘ１遺伝子 / 葉酸 / Tbx1遺伝子 / 心臓流出路発生 / 環境因子 / 心臓流出路 / 発生分化 / 再生医学 / Hand2遺伝子 / Hand1遺伝子 / 心臓発生 / 四肺発生 / Hand遺伝子 / 四肢発生 / 心臓・四肢発生 / 形熊形成 / モデル動物 / 分子生物学 / 発生医学 / 細胞分化 / 形態形成 Less

Genetic-environmental interaction for congenital cardiovascular disease
- Principal Investigator
  
  YAMAGISHI Hiroyuki
- Project Period (FY)
  2019 – 2021
- Research Category
  
  Grant-in-Aid for Scientific Research (B)
- Review Section
  
  Basic Section 52050:Embryonic medicine and pediatrics-related
- Research Institution
  Keio University
A role of T-box genes in development of cardiovascular diseases
- Principal Investigator
  
  Yamagishi Hiroyuki
- Project Period (FY)
  2016 – 2018
- Research Category
  
  Grant-in-Aid for Scientific Research (B)
- Research Field
  
  Pediatrics
- Research Institution
  Keio University
Basic research of prevention and intervention for congenital cardiac outflow tract defects using animal models
- Principal Investigator
  
  Yamagishi Hiroyuki
- Project Period (FY)
  2013 – 2015
- Research Category
  
  Grant-in-Aid for Scientific Research (B)
- Research Field
  
  Pediatrics
- Research Institution
  Keio University
The genetic and environmental effect on defects of developing cardiac outflow tract and aortic arch
- Principal Investigator
  
  Maeda Jun
- Project Period (FY)
  2013 – 2015
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Research Field
  
  Pediatrics
- Research Institution
  Keio University
Molecular mechanisms underlying development and interaction of progenitor cells essential for cardiac outflow tract morphogenesis
- Principal Investigator
  
  YAMAGISHI Hiroyuki
- Project Period (FY)
  2010 – 2012
- Research Category
  
  Grant-in-Aid for Scientific Research (B)
- Research Field
  
  Pediatrics
- Research Institution
  Keio University
Tissue-specific redundancy of Hand genes in the cardiac and limbdevelopment
- Principal Investigator
  
  MAEDA Jun
- Project Period (FY)
  2010 – 2012
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Research Field
  
  Pediatrics
- Research Institution
  Keio University

All 2018 2016 2015 2013 2011 2010 Other

All Journal Article Presentation Book

[Book] A history and interaction of outflow progenitor cells implicated in “Takao syndrome”. In: Etiology and Morphogenesis of Congenital Heart Disease -From Gene Function and Cellular Interaction to Morphology-2016
- Author(s)
  Yamagishi H, Kodo K, Maeda J, Uchida K, Tsuchihashi T, Shibata A, Ishizaki R, Yamagishi C, Srivastava D
- Total Pages
  383
- Publisher
  Springer
- Data Source
  KAKENHI-PROJECT-16H05359
[Book] Modification of Cardiac Phenotype in Tbx1 Hypomorphic Mice. In: Etiology and Morphogenesis of Congenital Heart Disease -From Gene Function and Cellular Interaction to Morphology-2016
- Author(s)
  Tsuchihashi T, Maeda J, Ishizaki R, Shibata A, Uchida K, Srivastava D, Yamagishi H
- Total Pages
  383
- Publisher
  Springer
- Data Source
  KAKENHI-PROJECT-16H05359
[Book] Etiology and Morphogenesis of Congenital Heart Disease2016
- Author(s)
  Yamagishi H, Kodo K, Maeda J, Uchida K, Tsuchihashi T, Shibata A, Ishizaki R, Yamagishi C, Srivastava D
- Total Pages
  383
- Publisher
  Springer
- Data Source
  KAKENHI-PROJECT-25293238
[Book] EBM小児疾患の治療(五十嵐隆監修、石井正浩, ほか編)2011
- Author(s)
  土橋隆俊、山岸敬幸
- Total Pages
  707
- Publisher
  中外医学社
- Data Source
  KAKENHI-PROJECT-22390211
[Journal Article] Efficacy and safety of intravenous immunoglobulin plus prednisolone therapy in patients with Kawasaki disease (Post RAISE): a multicentre, prospective cohort study.2018
- Author(s)
  Miyata K, Kaneko T, Morikawa Y, Sakakibara H, Matsushima T, Misawa M, Takahashi T, Nakazawa M, Tamame T, Tsuchihashi T, Yamashita Y, Obonai T, Chiga M, Hori N, Komiyama O, Yamagishi H, Miura M; Post RAISE group.
- Journal Title
  
  Lancet Child Adolesc Health
  
  Volume: 2 Issue: 12 Pages: 855-862
- DOI
  10.1016/s2352-4642(18)30293-1
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-16H05359
[Journal Article] Pharyngeal arch artery defects and lethal malformations of the aortic arch and its branches in mice deficient for the Hrt1/Hey1 transcription factor.2016
- Author(s)
  Fujita M, Sakabe M, Ioka T, Watanabe Y, Kinugasa-Katayama Y, Tsuchihashi T, Utset MF, Yamagishi H, Nakagawa O.
- Journal Title
  
  Mechanisms of Development
  
  Volume: 139 Pages: 65-73
- DOI
  10.1016/j.mod.2015.11.002
- Peer Reviewed / Acknowledgement Compliant / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-15H04883, KAKENHI-PROJECT-26860127, KAKENHI-PROJECT-16H05359
[Journal Article] Hand2 function in second heart field progenitors is essential for cardiogenesis2011
- Author(s)
  Tsuchihashi T, Maeda J, Shin CH, Ivey KN, Black BL, Olson EN, Yamagishi H, Srivastava D
- Journal Title
  
  Dev Biol
  
  Volume: 351 Pages: 62-69
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-22390211
[Journal Article] Hand2 function in second heart field progenitors is essential for cardiogenesis2011
- Author(s)
  Tsuchihashi T, Yamagishi H, et al.
- Journal Title
  
  Developmental Biology
  
  Volume: 351 Pages: 62-69
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-22390211
[Journal Article] Hand2 function in second heart fieldprogenitors is essential forcardiogenesis2011
- Author(s)
  Tsuchihashi T, Maeda J, Shin CH, IveyKN, Black BL, Olson EN, Yamagishi H,Srivastava D.
- Journal Title
  
  Dev Biol
  
  Volume: 351 Pages: 62-69
- URL
  http://dx.doi.org/10.1016/j.ydbio.2010.12.023
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-22591192
[Journal Article] Mechanisms underlying early development of pulmonary vascular obstructive disease in Down syndrome: An imbalance in biosynthesis of thromboxane A2 and prostacyclin2010
- Author(s)
  Fukushima H, Kosaki K, Sato R, Yagihashi T, Gatayama R, Kodo K, Hayashi T, Nakazawa M, Tsuchihashi T, Maeda J, Kojima Y, Yamagishi H, Takahashi T
- Journal Title
  
  Am J Med Genet A
  
  Volume: 152A Pages: 1919-1924
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-22390211
[Presentation] 心臓流出路異常の表現型に関する遺伝子と環境因子の相互作用の検討2015
- Author(s)
  土橋隆俊
- Organizer
  第51回日本小児循環器学会総会・学術集会
- Place of Presentation
  ホテル日航東京（東京都港区）
- Year and Date
  2015-07-16
- Data Source
  KAKENHI-PROJECT-25461631
[Presentation] Understanding the developing mechanism of Truncus Arteriosus by Tbx1 hypomorphic mouse.2013
- Author(s)
  Understanding the developing mechanism of Truncus Arteriosus by Tbx1 hypomorphic mouse. Takatoshi Tsuchihashi, Reina Ishizaki, Akimichi Shibata, Keiko Uchida, Hiroyuki Yamagishi
- Organizer
  The 7th TAKAO International Symposium on Etiology and Morphogenesis of Congenital Heart Disease
- Place of Presentation
  Tokyo
- Data Source
  KAKENHI-PROJECT-25293238
[Presentation] Exploring a novel molecular mechanismunderlying the cardiac developmentimplicated in the outflow tract defects2011
- Author(s)
  Kodo K, Uchida K, Tsuchihashi T,Nakanishi T, Matsuoka R, Yamagishi H
- Organizer
  Academy of European Society of PediatricCardiology 2011
- Place of Presentation
  Granada,Spain
- Data Source
  KAKENHI-PROJECT-22591192
[Presentation] 心臓形成におけるTbx遺伝子ファミリーを中心とする遺伝子制御一次元管腔構造から三次元4チャンバー心臓へのリモデリング流出路発生におけるTBX1の必須な役割2010
- Author(s)
  土橋隆俊, 前田潤, 山岸千尋, 山岸敬幸
- Organizer
  第83回日本生化学会大会・第33回日本分子生物学会年会合同大会
- Place of Presentation
  兵庫県神戸市
- Data Source
  KAKENHI-PROJECT-22591192
[Presentation] Ｔbx1発現低下マウスを用いた総動脈幹症の形態形成機構の解明
- Author(s)
  土橋　隆俊
- Organizer
  第49回日本小児循環器学会総会・学術集会
- Place of Presentation
  国立オリンピック記念青少年総合センター
- Data Source
  KAKENHI-PROJECT-25461631
[Presentation] Enviromental modification for phenotype of truncus arteriosus in Tbx1 hypomorphic mice
- Author(s)
  土橋　隆俊
- Organizer
  The 7th TAKAO International Symposium
- Place of Presentation
  国立オリンピック記念青少年総合センター
- Data Source
  KAKENHI-PROJECT-25461631

1. YAMAGISHI Hiroyuki (40255500)

# of Collaborated Projects: 6 results

# of Collaborated Products: 13 results
2. UCHIDA Keiko (50286522)

# of Collaborated Projects: 4 results

# of Collaborated Products: 4 results
3. YUASA Shinsuke (90398628)

# of Collaborated Projects: 4 results

# of Collaborated Products: 0 results
4. KODO Kazuki (10338105)

# of Collaborated Projects: 2 results

# of Collaborated Products: 1 results
5. MAKINO Shinji (20306707)

# of Collaborated Projects: 2 results

# of Collaborated Products: 0 results
6. MAEDA Jun (00255506)

# of Collaborated Projects: 2 results

# of Collaborated Products: 2 results
7. IEDA MASAKI (70296557)

# of Collaborated Projects: 2 results

# of Collaborated Products: 0 results
8. YAMAGISHI Chihiro (10296618)

# of Collaborated Projects: 1 results

# of Collaborated Products: 4 results
9. SAKABE Masahide

# of Collaborated Projects: 0 results

# of Collaborated Products: 1 results
10. 中川修

# of Collaborated Projects: 0 results

# of Collaborated Products: 1 results
11. 渡邉裕介

# of Collaborated Projects: 0 results

# of Collaborated Products: 1 results
12. 片山由美

# of Collaborated Projects: 0 results

# of Collaborated Products: 1 results

TSUCHIHASHI Takatoshi 土橋 隆俊

Research Projects

Research Products

Co-Researchers

Genetic-environmental interaction for congenital cardiovascular disease

Principal Investigator

Project Period (FY)

Research Category

Review Section

Research Institution

A role of T-box genes in development of cardiovascular diseases

Principal Investigator

Project Period (FY)

Research Category

Research Field

Research Institution

Basic research of prevention and intervention for congenital cardiac outflow tract defects using animal models

Principal Investigator

Project Period (FY)

Research Category

Research Field

Research Institution

The genetic and environmental effect on defects of developing cardiac outflow tract and aortic arch

Principal Investigator

Project Period (FY)

Research Category

Research Field

Research Institution

Molecular mechanisms underlying development and interaction of progenitor cells essential for cardiac outflow tract morphogenesis

Principal Investigator

Project Period (FY)

Research Category

Research Field

Research Institution

Tissue-specific redundancy of Hand genes in the cardiac and limbdevelopment

Principal Investigator

Project Period (FY)

Research Category

Research Field

Research Institution

[Book] A history and interaction of outflow progenitor cells implicated in “Takao syndrome”. In: Etiology and Morphogenesis of Congenital Heart Disease -From Gene Function and Cellular Interaction to Morphology-2016

Author(s)

Total Pages

Publisher

Data Source

[Book] Modification of Cardiac Phenotype in Tbx1 Hypomorphic Mice. In: Etiology and Morphogenesis of Congenital Heart Disease -From Gene Function and Cellular Interaction to Morphology-2016

Author(s)

Total Pages

Publisher

Data Source

[Book] Etiology and Morphogenesis of Congenital Heart Disease2016

Author(s)

Total Pages

Publisher

Data Source

[Book] EBM小児疾患の治療(五十嵐隆監修、石井正浩, ほか編)2011

Author(s)

Total Pages

Publisher

Data Source

[Journal Article] Efficacy and safety of intravenous immunoglobulin plus prednisolone therapy in patients with Kawasaki disease (Post RAISE): a multicentre, prospective cohort study.2018

Author(s)

Journal Title

DOI

Data Source

[Journal Article] Pharyngeal arch artery defects and lethal malformations of the aortic arch and its branches in mice deficient for the Hrt1/Hey1 transcription factor.2016

Author(s)

Journal Title

DOI

Data Source

[Journal Article] Hand2 function in second heart field progenitors is essential for cardiogenesis2011

Author(s)

Journal Title

Data Source

[Journal Article] Hand2 function in second heart field progenitors is essential for cardiogenesis2011

Author(s)

Journal Title

Data Source

[Journal Article] Hand2 function in second heart fieldprogenitors is essential forcardiogenesis2011

Author(s)

TSUCHIHASHI Takatoshi 土橋隆俊

[Presentation] 心臓形成におけるTbx遺伝子ファミリーを中心とする遺伝子制御一次元管腔構造から三次元4チャンバー心臓へのリモデリング流出路発生におけるTBX1の必須な役割2010