MATSUDA Takao 松田貴雄

Researcher Number	10304825
Other IDs
External Links
Affiliation (Current)	2025: 順天堂大学, 医学部, 客員教授
Affiliation (based on the past Project Information) *help	2004: 九州大学, 生体防御医学研究所, 講師 2003 – 2004: 九州大学, 大学病院, 助手 1998 – 2004: Medical Institute of Bioregulation Kyushu Univ.Research Associate, 生体防御医学研究所, 助手 1998: 九州大学, 生体防御医学研究所, 教授
Review Section/Research Field	Principal Investigator Obstetrics and gynecology / Obstetrics and gynecology Except Principal Investigator Obstetrics and gynecology / Obstetrics and gynecology / Biological Sciences / Embryonic/Neonatal medicine
Keywords	Principal Investigator HTF12 / choriocarcinoma / 絨毛癌 / KRAV / HOP / NECC1 / ヒト7番染色体 / サブトラクション / Forskolin / paternal origin … More / mole / homozygous deletion / Znフィンガー / スプライシング変異 / HTF-12 / 雄核発生 / 絨毛癌化 / フォルスコリン / ホモ欠失 / 雄性発生 / 胞状奇胎 / homeobox / Deterioration / Zn finger domain / KRAB domain / Choriocarcinoma / hPL / homeo domain / Zinc finger / Kruppel / ホメオボックス / 合胞体化 / 共通欠失領域 / human chromosome7 / subtraction / tumor suppressor gene / placenta / Villi / 造腫瘍性の抑制 / 7q11.22 / cDNAライブラリー / BAC / 癌抑制遺伝子 / 胎盤 / 絨毛 … More Except Principal Investigator Ras / p53 / MDM2 / ER / 子宮体癌 / 癌抑制遺伝子 / Cell senescence / ERα / cell senescence / endometrial cancer / p21 / 細胞老化 / ZAC / chromosome 1 / suppressor gene / 1番染色体 / cyclin G / HPV / E7 / cervical cancer / ORF12 / tumor suppressor gene / HDAC / NECC1 / 胞状奇胎 / DYRK1A / MNB / DSCR4 / SIM2 / DNA methylation / DNAメチル化 / HYMAI / BAC / chromosome 1q42 / Endometrial cancer / アポトーシス / G2 / NaB / P53 / Chromosome 1 / Molecular target therapy / Senescence gene / c-jun / bcl-2 / chromosome pulverization / 微小核融合 / DPC4 / HGF / 卵巣癌 / EGF / cell growth suppression / psolaren-conjugate antisense oligo DNA / E6 / Molecular diagnosis of metastasis / cell morphology alteration / DCC / senescence / 癌分子標的療法 / p21CDKインヒビター / MAPK / pRb / 絨毛癌 / Ovarian cancer / Apoptosis / Tumor suppressor gene / Genomic imprinting / メチル化 / LIT1 / Kip2 / カスパーゼ / ゲノムインプリント / target gene / ubiquitination / nuclear localization signal / Regulation of transcription / Down Syndrome / CpGアイランドメチル化 / 定量RT-PCR / 恒常発現細胞 / CpGアイランドのメチル化 / デイファレンシャルデイスプレイ法 / ARNT2 / 標的遺伝子 / ユビキチン化 / 核移行シグナル / 転写調節 / ダウン症 / HDAC inhibitor / Erα / Cancer / Molecular targeted Therapy / CDK結合領域 / mdm2 / 活性型Ras / 細胞老化誘導遺伝子 / lq42 / ROS / 分子標的治療 / エストロゲン受容体α / 絨毛細胞分化 / proline hydroxylase / 癌細胞老化 / MDM2蛋白 / 巨細胞 / トロホブラスト幹細胞 / ノックアウトマウス胎盤 / NECC1遺伝子 / Imprint control region / Complete mole / placenta / parthenogenetic embryo / TNDM / Genome imprint / 雄核発生胚 / ゲノムインプリンティング / 胎盤 / 単為発生胚 / 新生児一過性糖尿病 / ZAC遺伝子 / ゲノムィンプリンティング / 1q42-43 / シークエンスドラフト / H-Ras / K-Ras / Endometrium / Sodium butylate / M arrest / phosphorylation / acetylation / DNA damage / 細胞周期 / 婦人科癌 / 転写活性化 / ソディウムブチレイト / M期停止 / リン酸化 / アセチル化 / DNA損傷 / サイクリンG / p14ARF / ER α / [12Val] K-Ras / 1q42 and 7q11 / Sodium Bytylate / Senescence inducing gene / Choriocarcinoma / Endometrial Cancer / gene cloning / Chromosome 7 / ERドミナント・ネガティブ / p14^<ARF> / [12Val]K-Ras / 1q42and 7q11 / lymph node metastasis / telomerase / SM alpha actin / Mvo D / HPV E7 / c-iun / SM_αアクチン / リンパ節 / 子宮頚癌 / テロメレース / SMαアクチン / replicative senescence / 1q41-42 / 784H11 / telomere / human endometrial cancer / STFs / STF_s / STSマーカー / YAC / 微少核融合 / 放射線 / 染色体断片 / ヒト1番染色体 / 748H11 / D1S225-459 / テロメア / 子宮内膜癌抑制遺伝子 / DOC / a tumor suppressor gene on 1q / 変異型K・Ras / 形質転換 / エストロゲンリセプター / 変異型K-Ras / tumor supppressor gene on 1q / tumor suppressor gene on 1q / invasion / ovarian carcinoma / endometrial carcinoma / transformation / HaRF / HaFR / 運動能 / 浸潤能 / 腫瘍能 / SM-alphaactin / Uterine cervical cancer / Growth suppression / Antisence Oligo DNA / Gene diagnosis / Cytoskeleton / psolaren conjugate antisense oligo DNA / SM-αactn / SM-αactin / ドミナント・ネガティブSRF / SRF / トロホブラスト分化 / 海綿層 / 巨細胞層 / ノックアウト / Netrin / Sodium butrate / HIF-1 / EGLN-1 / HPH-2 / apoptosis / ORF-12 / Microallay analysis / transcriptional silencing / somatic mutation / TGF-β1 responsive / forkhead transcription factor / FOX C1 / 細胞外マトリックス / マイクロアレイ / SOCS1 / STAT / JAK / 増殖・分化・癌化 / 絨毛細胞 / 癌 / Sodium Butyrate / インプリント遺伝子 / インプリンティング遺伝子 / SMAP31 / RCR-サブトラクション / 7番染色体 / がん抑制遺伝子 Less

絨毛トロホブラストにおけるNECC1シグナル伝達系とその機能の解明
- Principal Investigator
  
  和氣徳夫
- Project Period (FY)
  2004 – 2005
- Research Category
  
  Grant-in-Aid for Exploratory Research
- Research Field
  
  Obstetrics and gynecology
- Research Institution
  Kyushu University
子宮体癌に特徴的な遺伝子変異に基づいた細胞死誘導機構の解明と癌遺伝子治療への応用
- Principal Investigator
  
  加藤秀則
- Project Period (FY)
  2003 – 2005
- Research Category
  
  Grant-in-Aid for Scientific Research (B)
- Research Field
  
  Obstetrics and gynecology
- Research Institution
  Kyushu University
Genomic imprinting and carcinogenesis
- Principal Investigator
  
  ARIMA Takahiro
- Project Period (FY)
  2003 – 2004
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Research Field
  
  Obstetrics and gynecology
- Research Institution
  KYUSHU UNIVERSITY
The functional analysis of the putative choriocarcinoma suppressor gene, HTF12 in choriocarcinoma.Principal Investigator
- Principal Investigator
  
  MATSUDA Takao
- Project Period (FY)
  2003 – 2004
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Research Field
  
  Obstetrics and gynecology
- Research Institution
  KYUSHU UNIVERSITY
TGF-β応答性FOX C-1遺伝子の機能解析及びそのシグナル伝達路の同定
- Principal Investigator
  
  和氣徳夫
- Project Period (FY)
  2002 – 2003
- Research Category
  
  Grant-in-Aid for Exploratory Research
- Research Field
  
  Obstetrics and gynecology
- Research Institution
  Kyushu University
Molecular targeted therapy by inducing cancer cell senesence
- Principal Investigator
  
  WAKE Norio
- Project Period (FY)
  2002 – 2006
- Research Category
  
  Grant-in-Aid for Scientific Research (S)
- Research Field
  
  Obstetrics and gynecology
- Research Institution
  KYUSHU UNIVERCITY
Regulation of expression and funcional analysis of Down syndrome gene
- Principal Investigator
  
  SHIMIZU Yoshiko
- Project Period (FY)
  2002 – 2004
- Research Category
  
  Grant-in-Aid for Scientific Research (B)
- Research Field
  
  Embryonic/Neonatal medicine
- Research Institution
  Kyorin University
絨毛癌細胞における増殖・分化の制御機構と癌化
- Principal Investigator
  
  和氣徳夫
- Project Period (FY)
  2001
- Research Category
  
  Grant-in-Aid for Scientific Research on Priority Areas (C)
- Review Section
  
  Biological Sciences
- Research Institution
  Kyushu University
HDAC阻害剤による癌細胞での老化誘導と癌抑制遺伝子の再発現
- Principal Investigator
  
  和氣徳夫
- Project Period (FY)
  2001
- Research Category
  
  Grant-in-Aid for Exploratory Research
- Research Field
  
  Obstetrics and gynecology
- Research Institution
  Kyushu University
Genomic imprinting on the development of the human trophoblastic
- Principal Investigator
  
  ARIMA Takahiro
- Project Period (FY)
  2001 – 2002
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Research Field
  
  Obstetrics and gynecology
- Research Institution
  Kyushu University
The analysis of OS-4 like gene and homeo protein like gene as a putative choriocarcinoma suppressor gene.Principal Investigator
- Principal Investigator
  
  MATSUDA Takao
- Project Period (FY)
  2001 – 2002
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Research Field
  
  Obstetrics and gynecology
- Research Institution
  Kyushu University
絨毛癌化の分子機構
- Principal Investigator
  
  和氣徳夫
- Project Period (FY)
  2000
- Research Category
  
  Grant-in-Aid for Scientific Research on Priority Areas (C)
- Review Section
  
  Biological Sciences
- Research Institution
  Kyushu University
p53・p21を分子標的とした癌の新規治療手段の開発
- Principal Investigator
  
  和氣徳夫
- Project Period (FY)
  2000
- Research Category
  
  Grant-in-Aid for Exploratory Research
- Research Field
  
  Obstetrics and gynecology
- Research Institution
  Kyushu University
Molecular mechanism of endometrial carcinoma development and their application for the new molecular target therapy
- Principal Investigator
  
  WAKE Norio
- Project Period (FY)
  2000 – 2001
- Research Category
  
  Grant-in-Aid for Scientific Research (B)
- Research Field
  
  Obstetrics and gynecology
- Research Institution
  Kyushu University
The cloning of a tumor suppressor gene against uterine endometrial cancer from the BAC clone that retains senescence-inducing ability to endomctrial cancer cell lines
- Principal Investigator
  
  KATO Hidenori
- Project Period (FY)
  2000 – 2001
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Research Field
  
  Obstetrics and gynecology
- Research Institution
  KYUSHU UNIVERSITY
Molecular mechanism of cell senescence
- Principal Investigator
  
  WAKE Norio
- Project Period (FY)
  1999 – 2001
- Research Category
  
  Grant-in-Aid for Scientific Research (B)
- Research Field
  
  Obstetrics and gynecology
- Research Institution
  KYUSHU UNIVERSITY
Functional role of cyclin G for p53-dependent G2/M arrest by DNA
- Principal Investigator
  
  NISHIDA Jun-ichi
- Project Period (FY)
  1999 – 2000
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Research Field
  
  Obstetrics and gynecology
- Research Institution
  KYUSHU UNIVERSITY
Isolation and Identification of Tumor suppressor gene in choriocarcinoma.Principal Investigator
- Principal Investigator
  
  MATSUDA Takao
- Project Period (FY)
  1999 – 2000
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Research Field
  
  Obstetrics and gynecology
- Research Institution
  KYUSHU UNIVERSITY
絨毛癌発生の分子機構
- Principal Investigator
  
  WAKE Norio
- Project Period (FY)
  1998 – 1999
- Research Category
  
  Grant-in-Aid for Scientific Research on Priority Areas (A)
- Research Field
  
  Obstetrics and gynecology
- Research Institution
  Kyushu University
Molecular mechanism of endometrial cancer and its application to gene diagnosis
- Principal Investigator
  
  WAKE Norio
- Project Period (FY)
  1997 – 1999
- Research Category
  
  Grant-in-Aid for Scientific Research (B)
- Research Field
  
  Obstetrics and gynecology
- Research Institution
  KYUSHU UNIVERSITY
The establishment of chromosome engineering for the gene cloning
- Principal Investigator
  
  KATO Hidenori
- Project Period (FY)
  1997 – 1999
- Research Category
  
  Grant-in-Aid for Scientific Research (B)
- Research Field
  
  Obstetrics and gynecology
- Research Institution
  KYUSHU UNIVERSITY
Transcriptional analysis of HPV16E7.
- Principal Investigator
  
  NISHIDA Jun-ichi
- Project Period (FY)
  1997 – 1998
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Research Field
  
  Obstetrics and gynecology
- Research Institution
  KYUSHU UNIVERSITY
Development of new therapy for uterine cervical carcinoma
- Principal Investigator
  
  WAKE Norio
- Project Period (FY)
  1996 – 1998
- Research Category
  
  Grant-in-Aid for Scientific Research (A)
- Research Field
  
  Obstetrics and gynecology
- Research Institution
  KYUSHU UNIVERSITY
Analysis of signal transduction associate with carcinogenesis and progression in endometrial and ovarian carcinoma.
- Principal Investigator
  
  KATO Kiyoko
- Project Period (FY)
  1996 – 1998
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Research Field
  
  Obstetrics and gynecology
- Research Institution
  KYUSHU UNIVERSITY

All 2006 2005 2003

All Journal Article

[Journal Article] Induction of human endometrial cancer cell senescence through modulation of HIF-1α activity byEGLN12006
- Author(s)
  Kato H, Inoue T, Asanoma K, Nishimura C, Matsuda T, Wake N
- Journal Title
  
  International Journal of Cancer 118
  
  Pages: 1144-1153
- Description
  「研究成果報告書概要(和文)」より
- Data Source
  KAKENHI-PROJECT-14104014
[Journal Article] Induction of human endometrial cancer cell senescence through modulation of HIF-1α activity by EGLN12006
- Author(s)
  Kato H, Inoue T, Asanoma K, Nishimura C, Matsuda T, Wake N
- Journal Title
  
  International Journal of Cancer 118,
  
  Pages: 1144-1153
- Data Source
  KAKENHI-PROJECT-14104014
[Journal Article] Activation of STAT3/5 Signal Pathways in Complete Mole and Repression in Choriocarcinoma Cell Lines2006
- Author(s)
  Kato H, Inoue T, Asanoma K, Matsuda T, Yoshikawa Y, Wake N
- Journal Title
  
  Journal of Reproductive Medicine 51
  
  Pages: 41-48
- Description
  「研究成果報告書概要(和文)」より
- Data Source
  KAKENHI-PROJECT-14104014
[Journal Article] ダウン症関連遺伝子DSCR4の発現解析2005
- Author(s)
  浅井聡子, 清水元, 八巻明子, 松田貴雄, 清水淑子
- Journal Title
  
  杏林医会誌 36
  
  Pages: 32-41
- NAID
  110002702815
- Description
  「研究成果報告書概要(和文)」より
- Data Source
  KAKENHI-PROJECT-14370323
[Journal Article] ダウン症関連遺伝子DSCR4の発現解析2005
- Author(s)
  浅井聡子, 清水元, 八巻明子, 松田貴雄, 清水淑子
- Journal Title
  
  杏林医学会雑誌 36・1(印刷中)
- NAID
  110002702815
- Data Source
  KAKENHI-PROJECT-14370323
[Journal Article] Genetics and molecular markers in gestational trophoblastic disease with special reference to their clinical application.2003
- Author(s)
  Matsuda T et al.
- Journal Title
  
  Best Practice & Research Clinical Obstetrics and Gynecology 17
  
  Pages: 827-836
- Description
  「研究成果報告書概要(欧文)」より
- Data Source
  KAKENHI-PROJECT-15591759
[Journal Article] Genetics and molecular markers in gestational trophoblastic disease with special reference to their clinical application.2003
- Author(s)
  Matsuda T et al.
- Journal Title
  
  Best Practice & Research Clinical Obstetrics and Gynecology 17,6
  
  Pages: 827-836
- Description
  「研究成果報告書概要(和文)」より
- Data Source
  KAKENHI-PROJECT-15591759
[Journal Article] II腫瘍絨毛癌発生の分子機構2003
- Author(s)
  松田貴雄, 他
- Journal Title
  
  産婦人科の世界 55
  
  Pages: 133-139
- Description
  「研究成果報告書概要(和文)」より
- Data Source
  KAKENHI-PROJECT-15591759

1. WAKE Norio (50158606)

# of Collaborated Projects: 23 results

# of Collaborated Products: 3 results
2. KATO Hidenori (60214392)

# of Collaborated Projects: 22 results

# of Collaborated Products: 3 results
3. KATO Kiyoko (10253527)

# of Collaborated Projects: 16 results

# of Collaborated Products: 3 results
4. ARIMA Takahiro (80253532)

# of Collaborated Projects: 14 results

# of Collaborated Products: 0 results
5. NISHIDA Jun-ichi (40264113)

# of Collaborated Projects: 11 results

# of Collaborated Products: 0 results
6. 浅野間和夫 (30380413)

# of Collaborated Projects: 3 results

# of Collaborated Products: 3 results
7. KOBAYASHI Hiroaki (70260700)

# of Collaborated Projects: 2 results

# of Collaborated Products: 0 results
8. 平川俊夫 (20218770)

# of Collaborated Projects: 2 results

# of Collaborated Products: 0 results
9. 井上貴史 (70380417)

# of Collaborated Projects: 2 results

# of Collaborated Products: 3 results
10. SONODA Kenzo (30294929)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
11. UEOKA Yosuke (50372743)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
12. SHIMIZU Yoshiko (50255410)

# of Collaborated Projects: 1 results

# of Collaborated Products: 2 results
13. KUDOH Jun (80178003)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
14. TAMURA Takashi (70146554)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
15. YAMAKI Akiko (40296546)

# of Collaborated Projects: 1 results

# of Collaborated Products: 2 results

MATSUDA Takao 松田 貴雄

Research Projects

Research Products

Co-Researchers

Principal Investigator

Project Period (FY)

Research Category

Research Field

Research Institution

Principal Investigator

Project Period (FY)

Research Category

Research Field

Research Institution

Principal Investigator

Project Period (FY)

Research Category

Research Field

Research Institution

The functional analysis of the putative choriocarcinoma suppressor gene, HTF12 in choriocarcinoma.Principal Investigator

Principal Investigator

Project Period (FY)

Research Category

Research Field

Research Institution

Principal Investigator

Project Period (FY)

Research Category

Research Field

Research Institution

Principal Investigator

Project Period (FY)

Research Category

Research Field

Research Institution

Principal Investigator

Project Period (FY)

Research Category

Research Field

Research Institution

Principal Investigator

Project Period (FY)

Research Category

Review Section

Research Institution

Principal Investigator

Project Period (FY)

Research Category

Research Field

Research Institution

Principal Investigator

Project Period (FY)

Research Category

Research Field

Research Institution

The analysis of OS-4 like gene and homeo protein like gene as a putative choriocarcinoma suppressor gene.Principal Investigator

Principal Investigator

Project Period (FY)

Research Category

Research Field

Research Institution

Principal Investigator

Project Period (FY)

Research Category

Review Section

Research Institution

Principal Investigator

Project Period (FY)

Research Category

Research Field

Research Institution

Principal Investigator

Project Period (FY)

Research Category

Research Field

Research Institution

Principal Investigator

Project Period (FY)

Research Category

Research Field

MATSUDA Takao 松田貴雄