MATSUDA Takao 松田貴雄

Researcher Number	10304825
Other IDs
External Links
Affiliation (based on the past Project Information) *help	2004: 九州大学, 生体防御医学研究所, 講師 2003 – 2004: 九州大学, 大学病院, 助手 1998 – 2004: Medical Institute of Bioregulation Kyushu Univ.Research Associate, 生体防御医学研究所, 助手 1998: 九州大学, 生体防御医学研究所, 教授
Review Section/Research Field	Principal Investigator Obstetrics and gynecology / Obstetrics and gynecology Except Principal Investigator Obstetrics and gynecology / Obstetrics and gynecology / Biological Sciences / Embryonic/Neonatal medicine
Keywords	Principal Investigator HTF12 / 絨毛癌 / choriocarcinoma / サブトラクション / ヒト7番染色体 / NECC1 / HOP / KRAV / 絨毛 / 胎盤 … More / 癌抑制遺伝子 / BAC / cDNAライブラリー / 7q11.22 / 造腫瘍性の抑制 / Villi / placenta / tumor suppressor gene / subtraction / human chromosome7 / 共通欠失領域 / 合胞体化 / ホメオボックス / Kruppel / Zinc finger / homeo domain / hPL / Choriocarcinoma / KRAB domain / Zn finger domain / Deterioration / homeobox / 胞状奇胎 / 雄性発生 / ホモ欠失 / フォルスコリン / 絨毛癌化 / 雄核発生 / HTF-12 / スプライシング変異 / Znフィンガー / homozygous deletion / mole / paternal origin / Forskolin … More Except Principal Investigator Ras / p53 / 癌抑制遺伝子 / 子宮体癌 / ER / MDM2 / 細胞老化 / p21 / endometrial cancer / cell senescence / ERα / Cell senescence / 胞状奇胎 / NECC1 / HDAC / tumor suppressor gene / ORF12 / cervical cancer / E7 / HPV / cyclin G / 1番染色体 / suppressor gene / chromosome 1 / ZAC / 絨毛癌 / pRb / MAPK / p21CDKインヒビター / 癌分子標的療法 / senescence / DCC / cell morphology alteration / Molecular diagnosis of metastasis / E6 / psolaren-conjugate antisense oligo DNA / cell growth suppression / EGF / 卵巣癌 / HGF / DPC4 / 微小核融合 / chromosome pulverization / bcl-2 / c-jun / Senescence gene / Molecular target therapy / Chromosome 1 / P53 / NaB / G2 / アポトーシス / Endometrial cancer / chromosome 1q42 / BAC / HYMAI / DNAメチル化 / DNA methylation / SIM2 / DSCR4 / MNB / DYRK1A / がん抑制遺伝子 / 7番染色体 / RCR-サブトラクション / SMAP31 / インプリンティング遺伝子 / インプリント遺伝子 / Sodium Butyrate / 癌 / 絨毛細胞 / 増殖・分化・癌化 / JAK / STAT / SOCS1 / マイクロアレイ / 細胞外マトリックス / FOX C1 / forkhead transcription factor / TGF-β1 responsive / somatic mutation / transcriptional silencing / Microallay analysis / ORF-12 / apoptosis / HPH-2 / EGLN-1 / HIF-1 / Sodium butrate / Netrin / ノックアウト / 巨細胞層 / 海綿層 / トロホブラスト分化 / SRF / ドミナント・ネガティブSRF / SM-αactin / SM-αactn / psolaren conjugate antisense oligo DNA / Cytoskeleton / Gene diagnosis / Antisence Oligo DNA / Growth suppression / Uterine cervical cancer / SM-alphaactin / 腫瘍能 / 浸潤能 / 運動能 / HaFR / HaRF / transformation / endometrial carcinoma / ovarian carcinoma / invasion / tumor suppressor gene on 1q / tumor supppressor gene on 1q / 変異型K-Ras / エストロゲンリセプター / 形質転換 / 変異型K・Ras / a tumor suppressor gene on 1q / DOC / 子宮内膜癌抑制遺伝子 / テロメア / D1S225-459 / 748H11 / ヒト1番染色体 / 染色体断片 / 放射線 / 微少核融合 / YAC / STSマーカー / STF_s / STFs / human endometrial cancer / telomere / 784H11 / 1q41-42 / replicative senescence / SMαアクチン / テロメレース / 子宮頚癌 / リンパ節 / SM_αアクチン / c-iun / HPV E7 / Mvo D / SM alpha actin / telomerase / lymph node metastasis / 1q42and 7q11 / [12Val]K-Ras / p14^<ARF> / ERドミナント・ネガティブ / Chromosome 7 / gene cloning / Endometrial Cancer / Choriocarcinoma / Senescence inducing gene / Sodium Bytylate / 1q42 and 7q11 / [12Val] K-Ras / ER α / p14ARF / サイクリンG / DNA損傷 / アセチル化 / リン酸化 / M期停止 / ソディウムブチレイト / 転写活性化 / 婦人科癌 / 細胞周期 / DNA damage / acetylation / phosphorylation / M arrest / Sodium butylate / Endometrium / K-Ras / H-Ras / シークエンスドラフト / 1q42-43 / ゲノムィンプリンティング / ZAC遺伝子 / 新生児一過性糖尿病 / 単為発生胚 / 胎盤 / ゲノムインプリンティング / 雄核発生胚 / Genome imprint / TNDM / parthenogenetic embryo / placenta / Complete mole / Imprint control region / NECC1遺伝子 / ノックアウトマウス胎盤 / トロホブラスト幹細胞 / 巨細胞 / MDM2蛋白 / 癌細胞老化 / proline hydroxylase / 絨毛細胞分化 / エストロゲン受容体α / 分子標的治療 / ROS / lq42 / 細胞老化誘導遺伝子 / 活性型Ras / mdm2 / CDK結合領域 / Molecular targeted Therapy / Cancer / Erα / HDAC inhibitor / ダウン症 / 転写調節 / 核移行シグナル / ユビキチン化 / 標的遺伝子 / ARNT2 / デイファレンシャルデイスプレイ法 / CpGアイランドのメチル化 / 恒常発現細胞 / 定量RT-PCR / CpGアイランドメチル化 / Down Syndrome / Regulation of transcription / nuclear localization signal / ubiquitination / target gene / ゲノムインプリント / カスパーゼ / Kip2 / LIT1 / メチル化 / Genomic imprinting / Tumor suppressor gene / Apoptosis / Ovarian cancer Less

絨毛トロホブラストにおけるNECC1シグナル伝達系とその機能の解明
- Principal Investigator
  
  和氣徳夫
- Project Period (FY)
  2004 – 2005
- Research Category
  
  Grant-in-Aid for Exploratory Research
- Research Field
  
  Obstetrics and gynecology
- Research Institution
  Kyushu University
子宮体癌に特徴的な遺伝子変異に基づいた細胞死誘導機構の解明と癌遺伝子治療への応用
- Principal Investigator
  
  加藤秀則
- Project Period (FY)
  2003 – 2005
- Research Category
  
  Grant-in-Aid for Scientific Research (B)
- Research Field
  
  Obstetrics and gynecology
- Research Institution
  Kyushu University
Genomic imprinting and carcinogenesis
- Principal Investigator
  
  ARIMA Takahiro
- Project Period (FY)
  2003 – 2004
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Research Field
  
  Obstetrics and gynecology
- Research Institution
  KYUSHU UNIVERSITY
The functional analysis of the putative choriocarcinoma suppressor gene, HTF12 in choriocarcinoma.Principal Investigator
- Principal Investigator
  
  MATSUDA Takao
- Project Period (FY)
  2003 – 2004
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Research Field
  
  Obstetrics and gynecology
- Research Institution
  KYUSHU UNIVERSITY
TGF-β応答性FOX C-1遺伝子の機能解析及びそのシグナル伝達路の同定
- Principal Investigator
  
  和氣徳夫
- Project Period (FY)
  2002 – 2003
- Research Category
  
  Grant-in-Aid for Exploratory Research
- Research Field
  
  Obstetrics and gynecology
- Research Institution
  Kyushu University
Molecular targeted therapy by inducing cancer cell senesence
- Principal Investigator
  
  WAKE Norio
- Project Period (FY)
  2002 – 2006
- Research Category
  
  Grant-in-Aid for Scientific Research (S)
- Research Field
  
  Obstetrics and gynecology
- Research Institution
  KYUSHU UNIVERCITY
Regulation of expression and funcional analysis of Down syndrome gene
- Principal Investigator
  
  SHIMIZU Yoshiko
- Project Period (FY)
  2002 – 2004
- Research Category
  
  Grant-in-Aid for Scientific Research (B)
- Research Field
  
  Embryonic/Neonatal medicine
- Research Institution
  Kyorin University
絨毛癌細胞における増殖・分化の制御機構と癌化
- Principal Investigator
  
  和氣徳夫
- Project Period (FY)
  2001
- Research Category
  
  Grant-in-Aid for Scientific Research on Priority Areas (C)
- Review Section
  
  Biological Sciences
- Research Institution
  Kyushu University
HDAC阻害剤による癌細胞での老化誘導と癌抑制遺伝子の再発現
- Principal Investigator
  
  和氣徳夫
- Project Period (FY)
  2001
- Research Category
  
  Grant-in-Aid for Exploratory Research
- Research Field
  
  Obstetrics and gynecology
- Research Institution
  Kyushu University
Genomic imprinting on the development of the human trophoblastic
- Principal Investigator
  
  ARIMA Takahiro
- Project Period (FY)
  2001 – 2002
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Research Field
  
  Obstetrics and gynecology
- Research Institution
  Kyushu University
The analysis of OS-4 like gene and homeo protein like gene as a putative choriocarcinoma suppressor gene.Principal Investigator
- Principal Investigator
  
  MATSUDA Takao
- Project Period (FY)
  2001 – 2002
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Research Field
  
  Obstetrics and gynecology
- Research Institution
  Kyushu University
絨毛癌化の分子機構
- Principal Investigator
  
  和氣徳夫
- Project Period (FY)
  2000
- Research Category
  
  Grant-in-Aid for Scientific Research on Priority Areas (C)
- Review Section
  
  Biological Sciences
- Research Institution
  Kyushu University
p53・p21を分子標的とした癌の新規治療手段の開発
- Principal Investigator
  
  和氣徳夫
- Project Period (FY)
  2000
- Research Category
  
  Grant-in-Aid for Exploratory Research
- Research Field
  
  Obstetrics and gynecology
- Research Institution
  Kyushu University
Molecular mechanism of endometrial carcinoma development and their application for the new molecular target therapy
- Principal Investigator
  
  WAKE Norio
- Project Period (FY)
  2000 – 2001
- Research Category
  
  Grant-in-Aid for Scientific Research (B)
- Research Field
  
  Obstetrics and gynecology
- Research Institution
  Kyushu University
The cloning of a tumor suppressor gene against uterine endometrial cancer from the BAC clone that retains senescence-inducing ability to endomctrial cancer cell lines
- Principal Investigator
  
  KATO Hidenori
- Project Period (FY)
  2000 – 2001
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Research Field
  
  Obstetrics and gynecology
- Research Institution
  KYUSHU UNIVERSITY
Molecular mechanism of cell senescence
- Principal Investigator
  
  WAKE Norio
- Project Period (FY)
  1999 – 2001
- Research Category
  
  Grant-in-Aid for Scientific Research (B)
- Research Field
  
  Obstetrics and gynecology
- Research Institution
  KYUSHU UNIVERSITY
Functional role of cyclin G for p53-dependent G2/M arrest by DNA
- Principal Investigator
  
  NISHIDA Jun-ichi
- Project Period (FY)
  1999 – 2000
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Research Field
  
  Obstetrics and gynecology
- Research Institution
  KYUSHU UNIVERSITY
Isolation and Identification of Tumor suppressor gene in choriocarcinoma.Principal Investigator
- Principal Investigator
  
  MATSUDA Takao
- Project Period (FY)
  1999 – 2000
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Research Field
  
  Obstetrics and gynecology
- Research Institution
  KYUSHU UNIVERSITY
絨毛癌発生の分子機構
- Principal Investigator
  
  WAKE Norio
- Project Period (FY)
  1998 – 1999
- Research Category
  
  Grant-in-Aid for Scientific Research on Priority Areas (A)
- Research Field
  
  Obstetrics and gynecology
- Research Institution
  Kyushu University
Molecular mechanism of endometrial cancer and its application to gene diagnosis
- Principal Investigator
  
  WAKE Norio
- Project Period (FY)
  1997 – 1999
- Research Category
  
  Grant-in-Aid for Scientific Research (B)
- Research Field
  
  Obstetrics and gynecology
- Research Institution
  KYUSHU UNIVERSITY
The establishment of chromosome engineering for the gene cloning
- Principal Investigator
  
  KATO Hidenori
- Project Period (FY)
  1997 – 1999
- Research Category
  
  Grant-in-Aid for Scientific Research (B)
- Research Field
  
  Obstetrics and gynecology
- Research Institution
  KYUSHU UNIVERSITY
Transcriptional analysis of HPV16E7.
- Principal Investigator
  
  NISHIDA Jun-ichi
- Project Period (FY)
  1997 – 1998
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Research Field
  
  Obstetrics and gynecology
- Research Institution
  KYUSHU UNIVERSITY
Development of new therapy for uterine cervical carcinoma
- Principal Investigator
  
  WAKE Norio
- Project Period (FY)
  1996 – 1998
- Research Category
  
  Grant-in-Aid for Scientific Research (A)
- Research Field
  
  Obstetrics and gynecology
- Research Institution
  KYUSHU UNIVERSITY
Analysis of signal transduction associate with carcinogenesis and progression in endometrial and ovarian carcinoma.
- Principal Investigator
  
  KATO Kiyoko
- Project Period (FY)
  1996 – 1998
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Research Field
  
  Obstetrics and gynecology
- Research Institution
  KYUSHU UNIVERSITY

All 2006 2005 2003

All Journal Article

[Journal Article] Induction of human endometrial cancer cell senescence through modulation of HIF-1α activity byEGLN12006
- Author(s)
  Kato H, Inoue T, Asanoma K, Nishimura C, Matsuda T, Wake N
- Journal Title
  
  International Journal of Cancer 118
  
  Pages: 1144-1153
- Description
  「研究成果報告書概要(和文)」より
- Data Source
  KAKENHI-PROJECT-14104014
[Journal Article] Induction of human endometrial cancer cell senescence through modulation of HIF-1α activity by EGLN12006
- Author(s)
  Kato H, Inoue T, Asanoma K, Nishimura C, Matsuda T, Wake N
- Journal Title
  
  International Journal of Cancer 118,
  
  Pages: 1144-1153
- Data Source
  KAKENHI-PROJECT-14104014
[Journal Article] Activation of STAT3/5 Signal Pathways in Complete Mole and Repression in Choriocarcinoma Cell Lines2006
- Author(s)
  Kato H, Inoue T, Asanoma K, Matsuda T, Yoshikawa Y, Wake N
- Journal Title
  
  Journal of Reproductive Medicine 51
  
  Pages: 41-48
- Description
  「研究成果報告書概要(和文)」より
- Data Source
  KAKENHI-PROJECT-14104014
[Journal Article] ダウン症関連遺伝子DSCR4の発現解析2005
- Author(s)
  浅井聡子, 清水元, 八巻明子, 松田貴雄, 清水淑子
- Journal Title
  
  杏林医会誌 36
  
  Pages: 32-41
- NAID
  110002702815
- Description
  「研究成果報告書概要(和文)」より
- Data Source
  KAKENHI-PROJECT-14370323
[Journal Article] ダウン症関連遺伝子DSCR4の発現解析2005
- Author(s)
  浅井聡子, 清水元, 八巻明子, 松田貴雄, 清水淑子
- Journal Title
  
  杏林医学会雑誌 36・1(印刷中)
- NAID
  110002702815
- Data Source
  KAKENHI-PROJECT-14370323
[Journal Article] Genetics and molecular markers in gestational trophoblastic disease with special reference to their clinical application.2003
- Author(s)
  Matsuda T et al.
- Journal Title
  
  Best Practice & Research Clinical Obstetrics and Gynecology 17
  
  Pages: 827-836
- Description
  「研究成果報告書概要(欧文)」より
- Data Source
  KAKENHI-PROJECT-15591759
[Journal Article] Genetics and molecular markers in gestational trophoblastic disease with special reference to their clinical application.2003
- Author(s)
  Matsuda T et al.
- Journal Title
  
  Best Practice & Research Clinical Obstetrics and Gynecology 17,6
  
  Pages: 827-836
- Description
  「研究成果報告書概要(和文)」より
- Data Source
  KAKENHI-PROJECT-15591759
[Journal Article] II腫瘍絨毛癌発生の分子機構2003
- Author(s)
  松田貴雄, 他
- Journal Title
  
  産婦人科の世界 55
  
  Pages: 133-139
- Description
  「研究成果報告書概要(和文)」より
- Data Source
  KAKENHI-PROJECT-15591759

1. WAKE Norio (50158606)

# of Collaborated Projects: 23 results

# of Collaborated Products: 3 results
2. KATO Hidenori (60214392)

# of Collaborated Projects: 22 results

# of Collaborated Products: 3 results
3. KATO Kiyoko (10253527)

# of Collaborated Projects: 16 results

# of Collaborated Products: 3 results
4. ARIMA Takahiro (80253532)

# of Collaborated Projects: 14 results

# of Collaborated Products: 0 results
5. NISHIDA Jun-ichi (40264113)

# of Collaborated Projects: 11 results

# of Collaborated Products: 0 results
6. 浅野間和夫 (30380413)

# of Collaborated Projects: 3 results

# of Collaborated Products: 3 results
7. KOBAYASHI Hiroaki (70260700)

# of Collaborated Projects: 2 results

# of Collaborated Products: 0 results
8. 平川俊夫 (20218770)

# of Collaborated Projects: 2 results

# of Collaborated Products: 0 results
9. 井上貴史 (70380417)

# of Collaborated Projects: 2 results

# of Collaborated Products: 3 results
10. SONODA Kenzo (30294929)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
11. UEOKA Yosuke (50372743)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
12. SHIMIZU Yoshiko (50255410)

# of Collaborated Projects: 1 results

# of Collaborated Products: 2 results
13. KUDOH Jun (80178003)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
14. TAMURA Takashi (70146554)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
15. YAMAKI Akiko (40296546)

# of Collaborated Projects: 1 results

# of Collaborated Products: 2 results

MATSUDA Takao 松田 貴雄

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The functional analysis of the putative choriocarcinoma suppressor gene, HTF12 in choriocarcinoma.Principal Investigator

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The analysis of OS-4 like gene and homeo protein like gene as a putative choriocarcinoma suppressor gene.Principal Investigator

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MATSUDA Takao 松田貴雄