Takei Yoshiyuki 竹井謙之

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TAKEI Yoshiyuki 竹井謙之

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Researcher Number	10306954
Other IDs
External Links
Affiliation (Current)	2025: 三重大学, 医学系研究科, 名誉教授
Affiliation (based on the past Project Information) *help	2017 – 2019: 三重大学, 医学系研究科, 教授 2013 – 2015: 三重大学, 医学(系)研究科(研究院), 教授 2003 – 2006: 順天堂大学, 医学部, 助教授 2005: 医学部, 助教授 1998 – 2002: 順天堂大学, 医学部, 講師
Review Section/Research Field	Principal Investigator Gastroenterology / Gastroenterology Except Principal Investigator Gastroenterology / Biomedical engineering/Biological material science / Gastroenterology / Science and Engineering
Keywords	Principal Investigator 類洞内皮細胞 / TNF-α / 細胞伝達 / アルコール性肝炎 / 消化器 / 細胞外小胞体 / サルコペニア / 動脈硬化 / 細胞外小胞 / アルコール性肝障害 … More / triplex DNA / gene delivery / sinusoidal endothelial cells / ステルス効果 / ヒアルロン酸グラフト化ポリLリジン櫛形共重合体 / 再生 / リホザイムライブラリ / ヒアルロン酸グラフト化ポリLリジン櫛型共重合体 / 3重鎖核酸法 / デコイ法 / 相分離性ナノ会合体 / 遺伝子デリバリ / ヒアルロン酸グラフト化ポリLリジン / ヒアルロン酸 / chemokine / TNBS colitis / inflammatory bowel disease / glycine / Amino acids / エンドトキシン / マクロファージ / 免疫薬理学的栄養作用 / 腸管 / アポトーシス / ケモカイン / TNBS腸炎 / 炎症性腸疾患 / グリシン / アミノ酸 / protein S / 組織リモデリング / 凝固・線溶系 / 動脈硬化症 / 脂肪性肝炎 … More Except Principal Investigator 肝星細胞 / 肝線維化 / adiponectin / leptin / hepatic fibrogenesis / 肝類洞壁細胞 / アディポネクチン / レプチン / NASH / エンドトキシン / Toll-like receptor (TLR) / アルコール性肝障害 / アンチジーン法 / 3重鎖DNA / 肝細胞 / ポリカチオン / グラフト共重合体 / オリゴヌクレオチド / バイオコンジュゲート / interferon / chronic hepatitis C / nonalcoholic steatohepatitis (NASH) / adipocytokines / アポトーシス / 抗ウイルス療法 / 低分子量ヘパリン / インターフェロン / アディポネクチンン / アディポサイトカイン / C型慢性肝炎 / 脂肪性肝疾患 / insulin resistance / hepatic stellate cells / TGF-β / adipokines / fatty liver / ケモカイン / PPAR-γ / 炎症性サイトカイン / インスリン抵抗性 / メタボリックシンドローム / 酸化ストレス / Collagen / Transcription factor / Polyion complex / Gene expression / DNA triplex / Oligonucleotides / Polycation / Graft copolymers / 遺伝子治療 / ポリカチオングラフト共重合体 / 転与因子 / コラーゲン / 転写因子 / ポリイオンコンプレックス / 遺伝子発現 / glycine / macrophages / inflammatory bowel diseases / alcoholic liver disease / innate immunity / bacterial toxins / Toll-like receptor(Tlr) / LPS binding protein / Toll-like receotor(Tlr) / 炎症性腸疾患 / TNF-α / Toll-like receptor / CD14 / Kupffer細胞 / マクロファージ / グリシン / 炎病性腸疾患 / 腸内細菌 / polymeric supra-molecular assembly / nanoparticle / Hyaluronic acid receptor / Gene-transfection of hepatic lectin / Biomimetics / Asialoglycoprotein-receptor / Hepatocyte / Liver specific Therapy / 原子間力顕微鏡 / 水晶発振子マイクロバランス(QCM)法 / 増殖因子 / 分化 / 肝細胞の形態や増殖 / アシアロ糖タンパク質モデル高分子(PVLA) / HepG2 / ポリリジン誘導体 / 遺伝子キャリアー / 肝臓類洞内皮細胞 / アラビノガラクタン / アシアロ糖タンパク質レセプタ / バイオミメティック糖質高分子 / グルコーストランスポーター / 肝レクチン / バイオミメティック / 肝臓 / 高分子超構造体 / ナノ粒子 / ヒアルロン酸レセプター / 肝レクチンの遺伝子導入 / バイオミメティックス / アシアロ糖タンパク質レセプター / 肝臓の標的治療 / siRNAライブラリ / リボザイムライブラリ / inverse genomics / ポリリシン / 肝類洞内皮細胞 / 遺伝子ベクター / ヒアルロン酸 / 遺伝子キャリヤ / トランスフェクション / DNA / 多糖 / 肝実質細胞 / 核内移行 / アシアロ糖タンパク質 / ペプチド核酸 / バイオテクノロジー / ナノバイオ / 高分子合成 / 生物生体工学 Less

Investigation of arteriosclerosis associating with liver derived extracellular vesicles in alcohlic liver diseasePrincipal Investigator
- Principal Investigator
  
  Takei Yoshiyuki
- Project Period (FY)
  2017 – 2019
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Research Field
  
  Gastroenterology
- Research Institution
  Mie University
Elucidation of the common mechanisms of tissue remodeling in nonalcoholic steatohapatitisPrincipal Investigator
- Principal Investigator
  
  Takei Yoshiyuki
- Project Period (FY)
  2013 – 2015
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Research Field
  
  Gastroenterology
- Research Institution
  Mie University
Role of adipocytokine in progression and therapeutic resistance in chronic liver diseases and hepatocellular carcinoma
- Principal Investigator
  
  IKEJIMA Kenichi
- Project Period (FY)
  2004 – 2006
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Research Field
  
  Gastroenterology
- Research Institution
  Juntendo University
Investigation of pathophysiology and therapeutic strategies for metabolic syndrome-related steatohepatitis
- Principal Investigator
  
  SATO Nobuhiro
- Project Period (FY)
  2003 – 2005
- Research Category
  
  Grant-in-Aid for Scientific Research (B)
- Research Field
  
  Gastroenterology
- Research Institution
  Juntendo University
Genetic Manipulation of Sinusoidal Endothelial CellsPrincipal Investigator
- Principal Investigator
  
  TAKEI Yoshiyuki
- Project Period (FY)
  2003 – 2005
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Research Field
  
  Gastroenterology
- Research Institution
  Juntendo University
Inverse genomicsを用いた肝線維化に関わる遺伝子の網羅的探索
- Principal Investigator
  
  SATO Nobuhiro
- Project Period (FY)
  2002 – 2004
- Research Category
  
  Grant-in-Aid for Exploratory Research
- Research Field
  
  Gastroenterology
- Research Institution
  Juntendo University
分子シンクロ機能を有するナノ会合体による遺伝子デリバリー
- Principal Investigator
  
  MARUYAMA Atsushi
- Project Period (FY)
  2001 – 2002
- Research Category
  
  Grant-in-Aid for Scientific Research on Priority Areas
- Review Section
  
  Science and Engineering
- Research Institution
  Tokyo Institute of Technology
Innate immune response to gut-derived bacterial toxins in gastrointestinal andhepatic disorders
- Principal Investigator
  
  SATO Nobuhiro
- Project Period (FY)
  2000 – 2002
- Research Category
  
  Grant-in-Aid for Scientific Research (B)
- Research Field
  
  Gastroenterology
- Research Institution
  Juntendo University School of Medicine
Polycationic copolymers having stabilizing activity toward triplex DNA
- Principal Investigator
  
  MARUYAMA Atsushi
- Project Period (FY)
  2000 – 2002
- Research Category
  
  Grant-in-Aid for Scientific Research (B)
- Research Field
  
  Biomedical engineering/Biological material science
- Research Institution
  Tokyo Institute of Technology
Amino acids as immuno-moduratory nutrients: therapeutic approaches for gastrointestinal and hepatic disorders.Principal Investigator
- Principal Investigator
  
  TAKEI Yoshiyuki
- Project Period (FY)
  1999 – 2001
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Research Field
  
  Gastroenterology
- Research Institution
  Juntendo University
Design of Polymeric Supramolecular-assembly for Targeted Therapy of Liver
- Principal Investigator
  
  AKAIKE Toshihiro
- Project Period (FY)
  1997 – 1999
- Research Category
  
  Grant-in-Aid for Scientific Research (A)
- Research Field
  
  Biomedical engineering/Biological material science
- Research Institution
  Tokyo Institute of Technology

All 2019 2018 2017 2015 2014 2013 2007 2006 2005 2004 Other

All Journal Article Presentation Book Patent

[Book] Hepatology Prectice Vol 2　 NASH・アルコール性肝障害の診療を極める2013
- Author(s)
  竹井謙之　（編集と執筆）、他
- Total Pages
  399
- Publisher
  文光堂
- Data Source
  KAKENHI-PROJECT-25460990
[Book] Genetic manipulation of liver sinusoidal endothelial cells. In Organ Microcirculation : A gateway to diagnostic and therapeutic interventions.2004
- Author(s)
  Takei Y, Ikejima K, Enomoto N, Maruyama A, Sato N.
- Publisher
  Springer-Verlag, Tokyo
- Data Source
  KAKENHI-PROJECT-15590690
[Journal Article] Serum Liver‐Type Fatty Acid Binding Protein Is a Possible Prognostic Factor in Human Chronic Liver Diseases From Chronic Hepatitis to Liver Cirrhosis and Hepatocellular Carcinoma2019
- Author(s)
  Eguchi Akiko、Hasegawa Hiroshi、Iwasa Motoh、Tamai Yasuyuki、Ohata Keiichi、Oikawa Tsuyoshi、Sugaya Takeshi、Takei Yoshiyuki
- Journal Title
  
  Hepatology Communications
  
  Volume: 3 Issue: 6 Pages: 825-837
- DOI
  10.1002/hep4.1350
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-17K09419
[Journal Article] Hypozincemia is associated with human hepatocarcinogenesis in hepatitis C virus‐related liver cirrhosis2019
- Author(s)
  Shigefuku Ryuta、Iwasa Motoh、Katayama Kazuhiro、Eguchi Akiko、Kawaguchi Takumi、Shiraishi Koichi、Ito Toshifumi、Suzuki Kazutomo、Koreeda Chizu、Ohtake Takaaki、Tokumoto Yoshio、Endo Ryujin、Kawamura Naohiro、Shiraki Makoto、et al.
- Journal Title
  
  Hepatology Research
  
  Volume: 49 Issue: 10 Pages: 1127-1135
- DOI
  10.1111/hepr.13388
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-19K08368, KAKENHI-PROJECT-17K09419
[Journal Article] Circulating Extracellular Vesicles and Their miR “Barcode” Differentiate Alcohol Drinkers With Liver Injury and Those Without Liver Injury in Severe Trauma Patients2019
- Author(s)
  Eguchi Akiko、Franz Niklas、Kobayashi Yoshinao、Iwasa Motoh、Wagner Nils、Hildebrand Frank、Takei Yoshiyuki、Marzi Ingo、Relja Borna
- Journal Title
  
  Frontiers in Medicine
  
  Volume: 6 Pages: 6-30
- DOI
  10.3389/fmed.2019.00030
- Peer Reviewed / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-17K09419
[Journal Article] Usefulness of Levocarnitine and/or Branched-Chain Amino Acids during Invasive Treatment for Hepatocellular Carcinoma.2015
- Author(s)
  Iwasa M, Sugimoto R, Ishihara T, Sekoguchi-Fujikawa N, Yoshikawa K, Mifuji-Moroka R, Tanaka H, Kobayashi Y, Hasegawa H, Takei Y.
- Journal Title
  
  J Nutr Sci Vitaminol (Tokyo)
  
  Volume: 61 Issue: 10 Pages: 433-440
- DOI
  10.1111/hepr.12471
- NAID
  130005125479
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-25460990
[Journal Article] Change in skeletal muscle mass after administering entecavir in patients with hepatitis B.2015
- Author(s)
  Iwasa M, Sugimoto R, Yoshikawa K, Miyachi H, Mifuji-Moroka R, Tanaka H,Kobayashi Y, Hasegawa H, Takei Y.
- Journal Title
  
  Nutrition.
  
  Volume: 31 Issue: 9 Pages: 1173-1174
- DOI
  10.1016/j.nut.2015.04.003
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-25460990
[Journal Article] Protein S exacerbates alcoholic hepatitis by stimulating liver natural killer T cells.2015
- Author(s)
  Chelakkot-Govindalayathil AL, Mifuji-Moroka R, D'Alessandro-Gabazza CN, Toda M, Matsuda Y, Gil-Bernabe P, Roeen Z, Yasuma T, Yano Y, Gabazza EC, Iwasa M, Takei Y.
- Journal Title
  
  J Thromb Haemost.
  
  Volume: １３（１） Issue: 1 Pages: 142-154
- DOI
  10.1111/jth.12789
- Peer Reviewed / Acknowledgement Compliant / Open Access
- Data Source
  KAKENHI-PROJECT-24590967, KAKENHI-PROJECT-24591128, KAKENHI-PROJECT-15K09170, KAKENHI-PROJECT-25460990
[Journal Article] Alcoholic liver disease and nonalcoholic fatty liver disease2015
- Author(s)
  Sugimoto K, Takei Y.
- Journal Title
  
  Nippon Shokakibyo Gakkai Zasshi
  
  Volume: 112 Issue: 9 Pages: 1641-1650
- DOI
  10.11405/nisshoshi.112.1641
- NAID
  130005096701
- ISSN
  0446-6586, 1349-7693
- Language
  Japanese
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-25460990
[Journal Article] Pathophysiology and management of hepatic encephalopathy 2014 update: Ammonia toxicity and hyponatremia.2015
- Author(s)
  Iwasa M, Takei Y
- Journal Title
  
  Hepatol Res
  
  Volume: 45 Issue: 12 Pages: 1155-1162
- DOI
  10.1111/hepr.12495
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-25460990
[Journal Article] Elevation of branched-chain amino acid levels in diabetes and NAFL and changes with antidiabetic drug treatment2015
- Author(s)
  Iwasa M, Ishihara T, Mifuji-Moroka R, Fujita N, Kobayashi Y, Hasegawa H, Iwata K, Kaito M, Takei Y
- Journal Title
  
  Obes Res Clin Pract
  
  Volume: 9 Issue: 3 Pages: 293-297
- DOI
  10.1016/j.orcp.2015.01.003
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-25460990
[Journal Article] NASHの最新の知見-基礎と臨床-　（座談会記録）2014
- Author(s)
  竹井謙之、正田純一、橋本悦子
- Journal Title
  
  最新医学
  
  Volume: 69 Pages: 1779-1790
- Data Source
  KAKENHI-PROJECT-25460990
[Journal Article] NAFAD/NASH; 肝発癌に至る病態と対策　（座談会記録）2014
- Author(s)
  坂本直哉、橋本悦子、米田政志、竹井謙之
- Journal Title
  
  肝胆膵
  
  Volume: 69 Pages: 435-444
- Data Source
  KAKENHI-PROJECT-25460990
[Journal Article] Evaluation and prognosis of sarcopenia using impedance analysis in patients with liver cirrhosis.2014
- Author(s)
  Iwasa M, Hara N, Terasaka E, Hattori A, Ishidome M, Mifuji-Moroka R, Miyachi H, Sugimoto R, Tanaka H, Fujita N, Kobayashi Y, Iwata K, Takei Y.
- Journal Title
  
  Hepatol Res
  
  Volume: 44 Issue: 10
- DOI
  10.1111/hepr.12217
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-25460990
[Journal Article] NAFLD/NASH2014
- Author(s)
  竹井謙之
- Journal Title
  
  別冊「医学のあゆみ」創刊3000号記念　「医学・医療のいまがわかるキーワード」
  
  Volume: 249 Pages: 423-423
- Data Source
  KAKENHI-PROJECT-25460990
[Journal Article] Treatment of non-alcoholic fatty liver disease2013
- Author(s)
  Takei Y
- Journal Title
  
  J Gastroenterol Hepatol
  
  Volume: Supp 4 Issue: S4 Pages: 79-80
- DOI
  10.1111/jgh.12242
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-25460990
[Journal Article] Nutrition therapy using a multidisciplinary team improves survival rates in patients with liver cirrhosis.2013
- Author(s)
  Iwasa M, Iwata K, Hara N, Hattori A, Ishidome M, Sekoguchi-Fujikawa N, Mifuji-Moroka R, Sugimoto R, Fujita N, Kobayashi Y, Takei Y
- Journal Title
  
  Nutrition
  
  Volume: 29 Issue: 11-12 Pages: 1418-1421
- DOI
  10.1016/j.nut.2013.05.016
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-25460990
[Journal Article] Branched-chain amino acid supplementation reduces oxidative stress and prolongs survival in rats with advanced liver cirrhosis.2013
- Author(s)
  Iwasa M, Kobayashi Y, Mifuji-Moroka R, Hara N, Miyachi H, Sugimoto R, Tanaka H, Fujita N, Gabazza EC, Takei Y
- Journal Title
  
  PLoS One
  
  Volume: 8 Issue: 7 Pages: e70309-e70309
- DOI
  10.1371/journal.pone.0070309
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-25460990
[Journal Article] Low molecular weight heparin prevents hepatic fibrogenesis caused carbon tetrachloride in the rat.2007
- Author(s)
  Abe W, Ikejima K, Lang T, Okumura K, Enomoto N, Kitamura T, Takei Y, Sato N.
- Journal Title
  
  J. Hepatol. 46
  
  Pages: 286-294
- Data Source
  KAKENHI-PROJECT-16590633
[Journal Article] Low molecular weight heparin prevents hepatic fibrogenesis caused by carbon tetrachloride in the rat.2007
- Author(s)
  Abe W, Ikejima K, Lang T, Okumura K, Enomoto N, Kitamura T, Takei Y, Sato N.
- Journal Title
  
  J.Hepatol. 46
  
  Pages: 286-294
- Description
  「研究成果報告書概要(欧文)」より
- Data Source
  KAKENHI-PROJECT-16590633
[Journal Article] Orthotopic Hepatocellular Carcinoma Model with a Controlled and Reproducible Tumorigenicity.2006
- Author(s)
  Okubo H, Takei Y, Serizawa N, Enomoto N, Ikejima K, Sato N.
- Journal Title
  
  Journal of Gastroenterology and Hepatology (in press)
- Data Source
  KAKENHI-PROJECT-15590690
[Journal Article] Effect of low-molecular-weight heparin on the commitment of bone marrow cells to liver sinusoidal endothelial cells in CC14-induced liver injury.2006
- Author(s)
  Serizawa N, Takei Y, Ohkubo H, Yamasina S, Enomoto N, Sato N.
- Journal Title
  
  Hepatol Res 34
  
  Pages: 207-213
- Description
  「研究成果報告書概要(欧文)」より
- Data Source
  KAKENHI-PROJECT-15590690
[Journal Article] Hepatic steatosis is a predictor of poor response to interferon α-2b and ribavirin combination therapy in Japanese patients with chronic hepatitis C.2006
- Author(s)
  Yaginuma R, Ikejima K, Okumura K, Kon K, Suzuki S, Takei Y, Sato N.
- Journal Title
  
  Hepatol Res. 35(1)
  
  Pages: 19-25
- NAID
  10020329566
- Description
  「研究成果報告書概要(欧文)」より
- Data Source
  KAKENHI-PROJECT-16590633
[Journal Article] Exacerbation of dietary steatohepatitis and fibrosis in obese, diabetic KK・A^y mice.2006
- Author(s)
  Okumura K, Ikejima K, Kon K, Abe W, Yamashina S, Enomoto N, Takei Y, Sato N.
- Journal Title
  
  Hepatol. Res. 36
  
  Pages: 217-228
- NAID
  10018640284
- Data Source
  KAKENHI-PROJECT-16590633
[Journal Article] Genetic Manipulation of Sinusoidal Endothelial Cells2006
- Author(s)
  Takei Y, et al.
- Journal Title
  
  Journal of Gastroenterology and Hepatology (in press)
- NAID
  110004011831
- Description
  「研究成果報告書概要(和文)」より
- Data Source
  KAKENHI-PROJECT-15590690
[Journal Article] Genetic Manipulation of Sinusoidal Endothelial Cells2006
- Author(s)
  Yoshiyuki Takei, Atsushi Maruyama, Kenichi Ikejima, et al.
- Journal Title
  
  Journal of Gastroenterology and Hepatology (in press)
- NAID
  110004011831
- Data Source
  KAKENHI-PROJECT-15590690
[Journal Article] Exacerbation of dietary steatohepatitis and fibrosis in obese, diabetic KK-Ay mice.2006
- Author(s)
  Okumura K, Ikejima K, Kon K, Abe W, Yamashina S, Enomoto N, Takei Y, Sato N.
- Journal Title
  
  Hepatol.Res. 36
  
  Pages: 217-228
- Description
  「研究成果報告書概要(欧文)」より
- Data Source
  KAKENHI-PROJECT-16590633
[Journal Article] 特集非B非C型肝炎 4.NASHと非B非C型肝炎 (2)NASHにおける病態進展の危険因子.2006
- Author(s)
  池嶋健一, 奥村京子, 今一義, 青山友則, 竹井謙之, 佐藤信紘.
- Journal Title
  
  臨床消火器内科 21(12)
  
  Pages: 1621-1628
- Data Source
  KAKENHI-PROJECT-16590633
[Journal Article] Sphingosine 1-phosphate protects rat liver sinusoidal endothelial cells from ethanol-induced apoptosis : role of intracellular calcium and nitric oxide.2006
- Author(s)
  Zheng DM, Kitamura T, Ikejima K, Enomoto N, Yamashina S, Suzuki S, Takei Y, Sato N.
- Journal Title
  
  Hepatology 44
  
  Pages: 1278-1287
- Data Source
  KAKENHI-PROJECT-16590633
[Journal Article] Effect of low-molecular-weight heparin on the commitment of bone marrow cells to liver sinusoidal endothelial cells in CC14-induced liver injury.2006
- Author(s)
  Serizawa N, Takei Y, Ohkubo H, Yamasina S, Enomoto N, Sato N.
- Journal Title
  
  Hepatology Research (in press)
- Data Source
  KAKENHI-PROJECT-15590690
[Journal Article] Protective effect of pioglitazone against endotoxin-induced liver injury through prevention of Kupffer cell sensitization.2005
- Author(s)
  Enomoto N, Takei Y, Yamashina S, Ikejima K, Kitamura T, Sato N.
- Journal Title
  
  Alcohol Clin.Exp.Res. 29(12 Suppl)
- Description
  「研究成果報告書概要(和文)」より
- Data Source
  KAKENHI-PROJECT-15390235
[Journal Article] Roles of Kupffer cells in alcoholic liver disease.2005
- Author(s)
  Takei Y, Arteel GE, Bergheim I, et al.
- Journal Title
  
  Alcohol Clin and Experimental Research 29
  
  Pages: 1116-1120
- Data Source
  KAKENHI-PROJECT-15590690
[Journal Article] Roles of Kupffer cells in alcoholic liver disease.2005
- Author(s)
  Takei Y, Arteel GE, Bergheim I, Lambert JC, McMullen MR. Nagy LE, Enomoto N, Sato N
- Journal Title
  
  Alcohol Clin Exp Res 29
  
  Pages: 1116-1120
- Description
  「研究成果報告書概要(欧文)」より
- Data Source
  KAKENHI-PROJECT-15590690
[Journal Article] Hepatic steatosis is a predictor of poor response to interferon α-2b and ribavirin combination therapy in Japanese patients with chronic hepatitis C.2005
- Author(s)
  Yaginuma R, Ikejima K, Okumura K, Kon K, Suzuki S, Takei Y, Sato N.
- Journal Title
  
  Hepatol.Res.
- NAID
  10020329566
- Data Source
  KAKENHI-PROJECT-16590633
[Journal Article] Glycine as a therapeutic immuno-nutrient for alcoholic liver disease.2005
- Author(s)
  Yamashina S, Ikejima K, Enomoto N, Takei Y, Sato N.
- Journal Title
  
  Alcohol Clin Exp Res. 29
- Description
  「研究成果報告書概要(欧文)」より
- Data Source
  KAKENHI-PROJECT-15590690
[Journal Article] Ethanol-induced sensitization to endotoxin in Kupffer cells is dependent upon oxidative stress.2005
- Author(s)
  Yamashina S, Takei Y, Ikejima K, Enomoto N, Kitamura T, Sato N.
- Journal Title
  
  Alcohol Clin Exp Res. 29
- Description
  「研究成果報告書概要(欧文)」より
- Data Source
  KAKENHI-PROJECT-15590690
[Journal Article] Ethanol-induced sensitization to endotoxin in Kupffer cells is dependent upon oxidative stress.2005
- Author(s)
  Yamashina S, Takei Y, Ikejima K, Enomoto N, Kitamura T, Sato N.
- Journal Title
  
  Alcohol Clin.Exp.Res. 29(12 Suppl)
- Description
  「研究成果報告書概要(和文)」より
- Data Source
  KAKENHI-PROJECT-15390235
[Journal Article] Roles of Kupffer cells in alcoholic liver disease.2005
- Author(s)
  Takei Y, Enomoto N, Ikejima K, Yamashina S, Kitamura T, Sato N
- Journal Title
  
  In Comprehensive Handbook of Alcohol Related Pathology (Academic Press, London) (Preedy VR and Watson RR, Eds)
  
  Pages: 749-759
- Description
  「研究成果報告書概要(欧文)」より
- Data Source
  KAKENHI-PROJECT-15590690
[Journal Article] Roles of Kupffer cells in alcoholic liver disease.2005
- Author(s)
  Takei Y, et al.
- Journal Title
  
  Alcohol Clin and Experimental Research 29
  
  Pages: 1116-1120
- Description
  「研究成果報告書概要(和文)」より
- Data Source
  KAKENHI-PROJECT-15590690
[Journal Article] Role of leptin in pathogenesis of NASH.2005
- Author(s)
  Ikejima K, Lang T, Yamashina S, Enomoto N, Takei Y, Sato N.
- Journal Title
  
  In NASH and Nutritional Therapy. (Tokyo : Springer-Verlag) (Okita K, Ed.)
  
  Pages: 44-49
- Description
  「研究成果報告書概要(欧文)」より
- Data Source
  KAKENHI-PROJECT-15590690
[Journal Article] The role of leptin in progression of non-alcoholic fatty liver disease.2005
- Author(s)
  Ikejima K, Okumura K, Lang T, Honda H, Abe W, Yamashina S, Enomoto N, Takei Y, Sato N.
- Journal Title
  
  Hepatol.Res. 33(2)
  
  Pages: 151-154
- NAID
  10016809329
- Description
  「研究成果報告書概要(和文)」より
- Data Source
  KAKENHI-PROJECT-15390235
[Journal Article] The role of leptin in progression of non-alcoholic fatty liver disease.2005
- Author(s)
  Ikejima K, Okumura K, Lang T, Honda H, Abe W, Yamashina S, Enomoto N, Takei Y, Sato N.
- Journal Title
  
  Hepatol Res. 33
  
  Pages: 151-154
- NAID
  10016809329
- Description
  「研究成果報告書概要(欧文)」より
- Data Source
  KAKENHI-PROJECT-15590690
[Journal Article] The role of leptin in progression of non-alcoholic fatty liver disease.2005
- Author(s)
  Ikejima K, Okumura K, Lang T, Honda H, Abe W, Yamashina S, Enomoto N, Takei Y, Sato N.
- Journal Title
  
  Hepatol.Res. 33(2)
  
  Pages: 151-154
- NAID
  10016809329
- Description
  「研究成果報告書概要(欧文)」より
- Data Source
  KAKENHI-PROJECT-16590633
[Journal Article] The glycine analogue, aminomethanesulfonic acid, inhibits LPS-induced production of TNF-alpha in isolated rat Kupffer cells and exerts hepatoprotective effects in mice.2004
- Author(s)
  Ishizaki-Koizumi S, Sonaka I, Takei Y, Ikejima K, Sato N.
- Journal Title
  
  Biochem Biophys Res Commun. 322
  
  Pages: 514-519
- Description
  「研究成果報告書概要(欧文)」より
- Data Source
  KAKENHI-PROJECT-15590690
[Journal Article] Expression of leptin receptors in hepatic sinusoidal cells.2004
- Author(s)
  Ikejima K, Lang T, Zhang YJ, Yamashina S, Honda H, Yoshikawa M, Hirose M, Enomoto N, Kitamura T, Takei Y, Sato N.
- Journal Title
  
  Comparative Hepatology 3(SupplI)
- Description
  「研究成果報告書概要(和文)」より
- Data Source
  KAKENHI-PROJECT-15390235
[Journal Article] Targeted gene delivery to sinusoidal endothelial cells : DNA nanoassociate bearing hyaluronan-glycocalyx.2004
- Author(s)
  Takei Y, Maruyama A, Ferdous A, Nishimura Y, Kawano S., Ikejima K, Okumura S., Asayama S, Nogawa M, Hashimoto M, Makino Y, Kinoshita M, Watanabe S, Akaike T, Lemasters JJ, Sato N.
- Journal Title
  
  FASEB J. (10.1096/fj.03-0494fje, published on line February 20, 2004) 18
  
  Pages: 699-701
- Description
  「研究成果報告書概要(欧文)」より
- Data Source
  KAKENHI-PROJECT-15590690
[Journal Article] Leptin facilitates proliferation of hepatic stellate cells through up regulation of platelet-derived growth factor receptor.2004
- Author(s)
  Lang T, Ikejima K, Yoshikawa M, Enomoto N, Iijima K, Kitamura T, Takei Y, Sato N.
- Journal Title
  
  Biochem.Biophys.Res.Commun. 323
  
  Pages: 1091-1095
- Description
  「研究成果報告書概要(和文)」より
- Data Source
  KAKENHI-PROJECT-15390235
[Journal Article] Leptin facilitates proliferation of hepatic stellate cells through up-regulation of platelet-derived growth factor receptor.2004
- Author(s)
  Lant T, Ikejima K, Yoshikawa M, Enomoto N, Iijima K, Kitamura T, Takei Y, Sato N.
- Journal Title
  
  Biochem.Biophys.Res.Commun. 323
  
  Pages: 1091-1095
- Data Source
  KAKENHI-PROJECT-16590633
[Journal Article] Leptin facilitates proliferation of hepatic stellate cells through up-regulation of platelet-derived growth factor receptor.2004
- Author(s)
  Lang T, Ikejima K, Yoshikawa M, Enomoto N, Iijima K, Kitamura T, Takei Y, Sato N.
- Journal Title
  
  Biochem.Biophys.Res.Commun. 323
  
  Pages: 1091-1095
- Description
  「研究成果報告書概要(欧文)」より
- Data Source
  KAKENHI-PROJECT-15590690
[Journal Article] Leptin facilitates proliferation of hepatic stellate cells through up-regulation of platelet-derived growth factor receptor.2004
- Author(s)
  Lang T, Ikejima K, Yoshikawa M, Enomoto N, Iijima K, Kitamura T, Takei Y, Sato N.
- Journal Title
  
  Biochem.Biophys.Res.Commun. 323
  
  Pages: 1091-1095
- Data Source
  KAKENHI-PROJECT-15390235
[Journal Article] NASHの病態2004
- Author(s)
  竹井謙之, 池嶋健一, 佐藤信紘
- Journal Title
  
  日本消火器病学会誌 101
  
  Pages: 1194-1203
- NAID
  10014292099
- Data Source
  KAKENHI-PROJECT-14657136
[Journal Article] Genetic manipulation of liver sinusoidal endothelial cells.2004
- Author(s)
  Takei Y, Ikejima K, Enomoto N, Maruyama A, Sato N.
- Journal Title
  
  In Organ Microcirculation : A gateway to diagnostic and therapeutic interventions. (Springer-Verlag, Tokyo ) (Ishii H, Ed.)
  
  Pages: 129-134
- NAID
  10012736253
- Description
  「研究成果報告書概要(欧文)」より
- Data Source
  KAKENHI-PROJECT-15590690
[Journal Article] Senescence marker protein-30 (SMP3O) regulates Akt activity and contributes to cell survival in Hep G2 cells.2004
- Author(s)
  Matsuyama S, Kitamura T, Zheng D, Fujita T, Ishigami A, Handa S, Maruyama N, Enomoto N, Ikejima K, Takei Y, Sato N.
- Journal Title
  
  Biochem.Biophys.Res.Commun. 321
  
  Pages: 386-390
- Description
  「研究成果報告書概要(欧文)」より
- Data Source
  KAKENHI-PROJECT-15590690
[Journal Article] Targeted gene delivery to sinusoidal endothelial cells : DNA nanoassociate bearing hyaluronan-glycocalyx.2004
- Author(s)
  Takei Y, Maruyama A, Ferdous A, Nishimura Y, et al.
- Journal Title
  
  FASEB Journal 18
  
  Pages: 699-701
- Data Source
  KAKENHI-PROJECT-15590690
[Journal Article] Burn injury sensitizes rat Kupffer cells via mechanisms dependent on gut-derived endotoxin.2004
- Author(s)
  Enomoto N, Takei Y, Yamashina S, Fukuda T, Suzuki S, Ikejima K, Kitamnra T, Sato N.
- Journal Title
  
  J.Gastroenterol. 39
  
  Pages: 1175-1181
- NAID
  10014091735
- Data Source
  KAKENHI-PROJECT-15390235
[Journal Article] Expression of leptin receptors in hepatic sinusoidal cells.2004
- Author(s)
  Ikejima K, Lang T, Zhang YJ, Yamashina S, Honda H, Yoshikawa M, Hirose M, Enomoto N, Kitamura T, Takei Y, Sato N.
- Journal Title
  
  Comparative Hepatology 3(Suppl I)
- Description
  「研究成果報告書概要(欧文)」より
- Data Source
  KAKENHI-PROJECT-15390235
[Journal Article] 肝類洞内皮細胞機能の遺伝子工学的制御2004
- Author(s)
  竹井謙之
- Journal Title
  
  医学のあゆみ 209
  
  Pages: 1035-1037
- Data Source
  KAKENHI-PROJECT-15590690
[Journal Article] The glycine analogue, aminomethanesulfonic acid, inhibits LPS-induced production of TNF-α in isolated rat Kupffer cells and exerts hepatoprotective effects in mice.2004
- Author(s)
  Ishizaki-Koizumi S, Sonaka I, Takei Y, Ikejima K, Sato N.
- Journal Title
  
  Biochem.Biophys.Res.Commun 322
  
  Pages: 514-519
- Data Source
  KAKENHI-PROJECT-15390235
[Journal Article] Expression of leptin receptors in hepatic sinusoidal cells.2004
- Author(s)
  Ikejima K, Lang T, Zhang YJ, Yamashina S, Honda H, Yoshikawa M, Hirose M, Enomoto N, Kitamura T, Takei Y, Sato N.
- Journal Title
  
  Comparative Hepatology3 (Suppl I) S12
- Description
  「研究成果報告書概要(欧文)」より
- Data Source
  KAKENHI-PROJECT-16590633
[Journal Article] NASHの病態2004
- Author(s)
  竹井謙之, 池嶋健一, 砂防信紘
- Journal Title
  
  日本消化器病学会雑誌 101
  
  Pages: 1194-1203
- NAID
  10014292099
- Data Source
  KAKENHI-PROJECT-16590633
[Journal Article] Targeted Gene delivery to sinusoidal endothelial cells : DNA nanoassociate bearing hyaluronan-glycocalyx.2004
- Author(s)
  Takei Y, Maruyama A, Sato N, et al.
- Journal Title
  
  FASEB J. 18
  
  Pages: 699-701
- Data Source
  KAKENHI-PROJECT-15390235
[Journal Article] Thalidomide prevents alcoholic liver injury in rats through inhibition of Kupffer cell sensitization.2004
- Author(s)
  Enomoto N, Takei Y, Hirose M, Ikejima K, Kitamura T, Sato N.
- Journal Title
  
  Comparative Hepatology 3(Suppl I)
- Description
  「研究成果報告書概要(欧文)」より
- Data Source
  KAKENHI-PROJECT-15390235
[Journal Article] Expression of leptin receptors in hepatic sinusoidal cells.2004
- Author(s)
  Ikejima K, Lang T, Zhang YJ, Yamashina S, Honda H, Yoshikawa M, Hirose M, Enomoto N, Kitamura T, Takei Y, Sato N.
- Journal Title
  
  Comparative Hepatology 3(Suppl I)
- Data Source
  KAKENHI-PROJECT-16590633
[Journal Article] NASHの病因:酸化ストレスとサイトカインの関与2004
- Author(s)
  竹井謙之, 池嶋健一, 佐藤信紘
- Journal Title
  
  肝臓 45
  
  Pages: 77-81
- NAID
  10012915441
- Data Source
  KAKENHI-PROJECT-16590633
[Journal Article] Targeted Gene delivery to sinusoidal endothelial cells : DNA nanoassociate bearing hyaluronan-glycocalyx.2004
- Author(s)
  Takei Y, Maruyama A, Ferdous A, Nishimura Y, Kawano S, Ikejima K, Okumura S, Asayama S, Nogawa M, Hashimoto M, Makino Y, Kinoshita M, Watanabe S, Akaike T, Lemasters JJ, Sato N.
- Journal Title
  
  FASEBJ. 18
  
  Pages: 699-701
- Description
  「研究成果報告書概要(欧文)」より
- Data Source
  KAKENHI-PROJECT-15390235
[Journal Article] Genetic Manipulation of Liver Sinusoidal Endothelial Cells.
- Author(s)
  Takei Y, Ikejima K, Enomoto N, Maruyama A, Sato N.
- Journal Title
  
  J Gastroenterol Hepatol (in press)
- NAID
  10012736253
- Description
  「研究成果報告書概要(欧文)」より
- Data Source
  KAKENHI-PROJECT-15590690
[Journal Article] Orthotopic Hepatocellular Carcinoma Model with a Controlled and Reproducible Tumorigenicity.
- Author(s)
  Okubo H, Takei Y, Serizawa N, Enomoto N, Ikejima K, Sato N.
- Journal Title
  
  J Gastro Heaptol (in press)
- Description
  「研究成果報告書概要(欧文)」より
- Data Source
  KAKENHI-PROJECT-15590690
[Patent] 遺伝子類導入方法2005
- Inventor(s)
  竹井謙之, 大久保裕直, 佐藤信紘
- Industrial Property Rights Holder
  学校法人順天堂, 日本化薬株式会社
- Industrial Property Number
  2005-314962
- Filing Date
  2005-10-28
- Description
  「研究成果報告書概要(和文)」より
- Data Source
  KAKENHI-PROJECT-15590690
[Patent] 遺伝子類導入方法2005
- Inventor(s)
  竹井謙之, 大久保裕直, 佐藤信紘
- Industrial Property Rights Holder
  学校法人順天堂, 日本化薬株式会社
- Industrial Property Number
  2005-314962
- Filing Date
  2005-10-28
- Data Source
  KAKENHI-PROJECT-15590690
[Presentation] ASSOCIATION AMONG SERUM BILE ACIDS,LIVER FIBROSIS AND SKELETAL MUSCLE VOLUME IN NAFLD AND BIOLOGICAL EFFECTS OF BILE ACIDS ON SKELETAL MUSCLE2019
- Author(s)
  Yoshinao Kobayashi,Yasuyuki Tamai,Akiko Eguchi,Mina Tenpaku,Ryuta Shigefuku,Motoh Iwasa, Yoshiyuki Takei
- Organizer
  AASLD 2019
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-17K09419
[Presentation] 肝細胞由来Extracellular vesiclesは肝星細胞を活性化することでアルコール性肝障害の病態進行に寄与する2019
- Author(s)
  江口暁子,岩佐元雄,竹井謙之,塚本秀和
- Organizer
  第26回肝細胞研究会　（シンポジウム）
- Data Source
  KAKENHI-PROJECT-17K09419
[Presentation] Extracellular vesicles in liver inflammation and damage2019
- Author(s)
  江口暁子,塚本秀和,Borna Relja,竹井謙之
- Organizer
  第34回日本Shock学会総会　（シンポジウム）
- Data Source
  KAKENHI-PROJECT-17K09419
[Presentation] 非アルコール性肝炎に関連するメタボリックリスク因子の上昇により肝細胞や脂肪細胞由来のExtracellular veicle数が増加する2019
- Author(s)
  江口暁子,小林由直,天白美奈,岩佐元雄,竹井謙之
- Organizer
  第９回肥満と消化器疾患研究会
- Data Source
  KAKENHI-PROJECT-17K09419
[Presentation] C1q MEDIATES LIVER FIBROSIS THROUGH CTGF ACTIVATION AND IS A PROGNOSTIC FACTOR FOR SURVIVAL IN RAT AND HUMAN CHRONIC LIVER DISEASES2019
- Author(s)
  Akiko Eguchi,Motoh Iwasa,Mina Tenpaku,Yoshinao Kobayashi,Yoshiyuki Takei
- Organizer
  AASLD 2019
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-17K09419
[Presentation] NAFLD患者における1次および2次胆汁酸のメタボリック関連因子および骨格筋に与える影響について2019
- Author(s)
  小林由直,江口暁子,竹井謙之
- Organizer
  第23回日本肝臓学会大会　（シンポジウム）
- Data Source
  KAKENHI-PROJECT-17K09419
[Presentation] Alcohol hepatitis マウスにおける肝細胞由来Extracellular vesiclesはmiRNA成分により肝星細胞を制御し、DAMP成分により肝マクロファージを制御する2019
- Author(s)
  江口暁子,岩佐元雄,竹井謙之
- Organizer
  第23回日本肝臓学会大会　（シンポジウム）
- Data Source
  KAKENHI-PROJECT-17K09419
[Presentation] NASH及びASHにおける障害肝細胞由来Extracellular vesiclesの病態進行への関与2019
- Author(s)
  江口暁子,岩佐元雄,竹井謙之
- Organizer
  第43回肝臓学会西部会　（シンポジウム）
- Data Source
  KAKENHI-PROJECT-17K09419
[Presentation] L-CARNITINE AND BRANCHED-CHAIN AMINO ACIDS ATTENUATE HEPATOCELLAR DAMEGE THROUGH REDUCTION OF LIVER LIPID PEROXIDES AND MAINTENANCE OF MITOCHONDRIAL INTEGRITY IN CIRRHOTIC RATS2019
- Author(s)
  Yasuyuki Tamai,Akiko Eguchi,Motoh Iwasa,Zhen Chen,Yue Wu,Jun Okabe,Hitoshi Chiba,Shu-Ping Hui,Yoshiyuki Takei
- Organizer
  AASLD 2019
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-17K09419
[Presentation] アルコール性肝障害が拓く生命医科学：serendipityの研究史2018
- Author(s)
  竹井謙之
- Organizer
  第54回　日本肝臓学会総会
- Invited
- Data Source
  KAKENHI-PROJECT-17K09419
[Presentation] Liver Parenchymal Cells and Sinusoidal Cells: Cell Sociology in Alcoholic Liver Disease2018
- Author(s)
  Yoshiyuki Takei
- Organizer
  19th Congress of International Society for Biomedical Research on Alcoholism (ISBRA)
- Invited / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-17K09419
[Presentation] Extracellualr vesicle miRNAs in alcoholic steatohepatitis2018
- Author(s)
  江口暁子、竹井謙之、Feldstein Ariel、塚本秀和
- Organizer
  平成30年度アルコール・薬物依存関連学会合同学術総会
- Data Source
  KAKENHI-PROJECT-17K09419
[Presentation] シンポジウム「アルコール性肝障害研究の最先端」総括発言2017
- Author(s)
  竹井謙之
- Organizer
  第52回日本アルコール・アディクション医学会学術総会
- Invited
- Data Source
  KAKENHI-PROJECT-17K09419
[Presentation] アルコール性肝障害とNAFLD：代謝に回帰する肝臓病学2017
- Author(s)
  竹井謙之
- Organizer
  日本消化器病学会東海支部第127回例会
- Invited
- Data Source
  KAKENHI-PROJECT-17K09419
[Presentation] アルコール性肝障害・NAFLD2017
- Author(s)
  竹井謙之
- Organizer
  第１０３回日本消化器病総会
- Invited
- Data Source
  KAKENHI-PROJECT-17K09419
[Presentation] 肝疾患における内臓肥満とサルコペニアの病態への関与2015
- Author(s)
  岩佐元雄、原なぎさ、竹井謙之
- Organizer
  第101回日本消化器病学会総会
- Place of Presentation
  仙台国際センター　（仙台市）
- Year and Date
  2015-04-23
- Data Source
  KAKENHI-PROJECT-25460990
[Presentation] Effect of Branched Chain Amino Acids on Iron Transport in the Liver and Small Intestine of a Cirrhotic Rat Model2015
- Author(s)
  Yoshinao Kobayashi, RyosukeSugimoto, Motoh Iwasa, Yoshiyuki Takei
- Organizer
  AASLD LIVER MEETING
- Place of Presentation
  米国　サンフランシスコ
- Year and Date
  2015-11-13
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-25460990
[Presentation] アルコール性肝障害におけるProtein Sの肝NKT細胞活性化を介した病態への関与.2015
- Author(s)
  諸岡留美、岩佐元雄、長谷川浩司、竹井謙之、ガバザエステバン
- Organizer
  第51回日本肝臓学会総会
- Place of Presentation
  ホテル日航熊本　（熊本市）
- Year and Date
  2015-05-21
- Data Source
  KAKENHI-PROJECT-25460990
[Presentation] Sarcopenic obesity impairs prognosis of patients with cirrhosis2015
- Author(s)
  Motoh Iwasa, Ryosuke Sugimoto, Yoshinao Kobayashi, Yoshiyuki Takei
- Organizer
  AASLD LIVER MEETING
- Place of Presentation
  米国　サンフランシスコ
- Year and Date
  2015-11-13
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-25460990
[Presentation] サルコペニアおよびサルコペニア肥満を合併した肝硬変の生命予後とその対策2015
- Author(s)
  原なぎさ、岩佐元雄、宮地洋英、杉本龍亮、諸岡留美、田中秀明、長谷川浩司、岩田加壽子、竹井謙之
- Organizer
  第51回日本肝臓学会総会
- Place of Presentation
  ホテル日航熊本　（熊本市）
- Year and Date
  2015-05-21
- Data Source
  KAKENHI-PROJECT-25460990
[Presentation] 鉄代謝障害と肝疾患2015
- Author(s)
  竹井謙之
- Organizer
  第39回日本鉄バイオサイエンス学会学術集会
- Place of Presentation
  岡山コンベンションセンター　（岡山市）
- Year and Date
  2015-08-29
- Invited
- Data Source
  KAKENHI-PROJECT-25460990
[Presentation] アルコール性肝障害患者における各種adipocytokineの動態解析2015
- Author(s)
  藤田尚己、宮地洋英、杉本龍亮、諸岡留美、田中秀明、岩佐元雄、長谷川浩司、竹井謙之
- Organizer
  第51回日本肝臓学会総会
- Place of Presentation
  ホテル日航熊本　（熊本市）
- Year and Date
  2015-05-21
- Data Source
  KAKENHI-PROJECT-25460990
[Presentation] ALDとNASHの治療学１：栄養療法2015
- Author(s)
  岩佐元雄、竹井謙之
- Organizer
  第50回日本アルコール・薬物医学会　第27回日本依存神経精神科学会
- Place of Presentation
  神戸国際会議場　（神戸市）
- Year and Date
  2015-10-11
- Data Source
  KAKENHI-PROJECT-25460990
[Presentation] Voxel-Based Morphometryを用いたアルコール性肝障害患者の脳画像解析2015
- Author(s)
  諸岡留美、岩佐元雄、吉川恭子、杉本龍亮、宮地洋英、長谷川浩司、小林由直、竹井謙之、石田聡
- Organizer
  第51回日本肝臓学会総会
- Place of Presentation
  ホテル日航熊本　（熊本市）
- Year and Date
  2015-05-21
- Data Source
  KAKENHI-PROJECT-25460990
[Presentation] 生活習慣がもたらす肝疾患：アルコール性肝障害とNAFLD2015
- Author(s)
  竹井謙之、長谷川浩司、岩佐元雄
- Organizer
  第51回日本肝臓学会総会
- Place of Presentation
  ホテル日航熊本　（熊本市）
- Year and Date
  2015-05-21
- Invited
- Data Source
  KAKENHI-PROJECT-25460990
[Presentation] Hepatic iron-mediated oxidative stress affects insulin resistance through the forkhead box-containing protein O subfamily-1 (foxo-1) pathway in chronic hepatitis C2013
- Author(s)
  Kobayashi Y, Iwasa M, Miyachi H, Takei Y
- Organizer
  AASLD (THE LIVER EETING 2013)
- Place of Presentation
  Washington DC, USA
- Data Source
  KAKENHI-PROJECT-25460990
[Presentation] Effect of branched-chain amino acids on iron and glucose metabolism in rats with liver cirrhosis2013
- Author(s)
  Kobayashi Y, Iwasa M, Miyachi H, Takei Y
- Organizer
  AASLD (THE LIVER EETING 2013)
- Place of Presentation
  Washington DC, USA
- Data Source
  KAKENHI-PROJECT-25460990
[Presentation] Protein S exacerbates acute alcohol-induced liver injury by enhancing acyivation of liver ntural killerT cells2013
- Author(s)
  Iwasa M, Takei Y, Fujita N, Moroka R, Tanaka H, Sugimoto R, Kobayashi Y, Gabazza E
- Organizer
  17th International Stmposium on Cells of the Hepatic Sinusoid
- Place of Presentation
  Osaka
- Data Source
  KAKENHI-PROJECT-25460990
[Presentation] Protein S exacerbates activation of liver natural killer T (NKT) cells during alcohol-induced liver injury2013
- Author(s)
  Miyachi H, Moroka R, Fujita N, Kobayashi Y, Iwasa M, Takei Y
- Organizer
  AASLD (THE LIVER EETING 2013)
- Place of Presentation
  Washington DC, USA
- Data Source
  KAKENHI-PROJECT-25460990
[Presentation] Protein SはNKT細胞の活性化を介して急性アルコール性肝障害を増悪させる
- Author(s)
  諸岡留美，岩佐元雄，杉本龍亮，宮地洋英，田中秀明，藤田尚己，小林由直，ガバザエステバン，竹井謙之
- Organizer
  第５０回日本肝臓学会総会
- Place of Presentation
  東京　ホテルニューオータニ
- Year and Date
  2014-05-29 – 2014-05-30
- Data Source
  KAKENHI-PROJECT-25460990
[Presentation] アルコール性および非アルコール性脂肪性肝疾患：病態連繋の共通点と差異
- Author(s)
  藤田尚己、持田智、竹井謙之
- Organizer
  第40回日本肝臓学会東部会特別企画
- Place of Presentation
  東京　京王プラザホテル
- Year and Date
  2014-11-27 – 2014-11-28
- Data Source
  KAKENHI-PROJECT-25460990
[Presentation] NAFLDの病態
- Author(s)
  竹井謙之
- Organizer
  第１００回日本消化器病学会総会　Research Forum 4　ディスカサント
- Place of Presentation
  東京　東京国際フォーラム
- Year and Date
  2014-04-23 – 2014-04-26
- Invited
- Data Source
  KAKENHI-PROJECT-25460990
[Presentation] 各種肝疾患における鉄過剰の臨床的意義とその成因の検討
- Author(s)
  藤田尚己，岩佐元雄，竹井謙之
- Organizer
  第５０回日本肝臓学会総会ワークショップ
- Place of Presentation
  東京　ホテルニューオータニ
- Year and Date
  2014-05-29 – 2014-05-30
- Data Source
  KAKENHI-PROJECT-25460990
[Presentation] Protein SはNKT細胞の活性化を介して急性アルコール性肝障害を増悪させる
- Author(s)
  竹井謙之、諸岡留美、岩佐元雄
- Organizer
  第２８回肝類洞経壁細胞研究会学術集会
- Place of Presentation
  岡山　アークホテル岡山
- Year and Date
  2014-12-13 – 2014-12-14
- Data Source
  KAKENHI-PROJECT-25460990
[Presentation] 肝脂肪化やメタボリック症候群関連因子に及ぼす飲酒習慣の影響
- Author(s)
  藤田尚己、長谷川浩司、竹井謙之
- Organizer
  第１８回日本肝臓学会大会ワークショップ
- Place of Presentation
  神戸神戸国際会議場　ポートピアホテル
- Year and Date
  2014-10-23 – 2014-10-26
- Data Source
  KAKENHI-PROJECT-25460990

1. IKEJIMA Kenichi (20317382)

# of Collaborated Projects: 6 results

# of Collaborated Products: 41 results
2. MARUYAMA Atsushi (40190566)

# of Collaborated Projects: 4 results

# of Collaborated Products: 7 results
3. ENOMOTO Nobuyuki (20348973)

# of Collaborated Projects: 4 results

# of Collaborated Products: 33 results
4. SATO Nobuhiro (90028358)

# of Collaborated Projects: 3 results

# of Collaborated Products: 13 results
5. OGIHARA Tatuo (80011196)

# of Collaborated Projects: 2 results

# of Collaborated Products: 0 results
6. HIROSE Miyoko (70266039)

# of Collaborated Projects: 2 results

# of Collaborated Products: 0 results
7. GABAZZA Esteban (00293770)

# of Collaborated Projects: 1 results

# of Collaborated Products: 5 results
8. IWASA Motoh (80378299)

# of Collaborated Projects: 1 results

# of Collaborated Products: 24 results
9. FUJITA Naoki (80378398)

# of Collaborated Projects: 1 results

# of Collaborated Products: 11 results
10. AKAIKE Toshihiro (30101207)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
11. WATANABE Yoshifumi (40231013)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
12. TERAI Takeshi (90245704)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
13. OHKUSA Toshifumi (50160445)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
14. 江口暁子 (00598980)

# of Collaborated Projects: 1 results

# of Collaborated Products: 12 results
15. 山本憲彦 (60501963)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
16. 長谷川浩司 (90737008)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
17. 白木亮

# of Collaborated Projects: 0 results

# of Collaborated Products: 1 results

Takei Yoshiyuki 竹井 謙之

TAKEI Yoshiyuki 竹井 謙之

Research Projects

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Investigation of arteriosclerosis associating with liver derived extracellular vesicles in alcohlic liver diseasePrincipal Investigator

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Elucidation of the common mechanisms of tissue remodeling in nonalcoholic steatohapatitisPrincipal Investigator

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Role of adipocytokine in progression and therapeutic resistance in chronic liver diseases and hepatocellular carcinoma

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Investigation of pathophysiology and therapeutic strategies for metabolic syndrome-related steatohepatitis

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Genetic Manipulation of Sinusoidal Endothelial CellsPrincipal Investigator

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Inverse genomicsを用いた肝線維化に関わる遺伝子の網羅的探索

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分子シンクロ機能を有するナノ会合体による遺伝子デリバリー

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Innate immune response to gut-derived bacterial toxins in gastrointestinal andhepatic disorders

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Polycationic copolymers having stabilizing activity toward triplex DNA

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Amino acids as immuno-moduratory nutrients: therapeutic approaches for gastrointestinal and hepatic disorders.Principal Investigator

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Design of Polymeric Supramolecular-assembly for Targeted Therapy of Liver

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[Book] Hepatology Prectice Vol 2 NASH・アルコール性肝障害の診療を極める2013

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[Book] Genetic manipulation of liver sinusoidal endothelial cells. In Organ Microcirculation : A gateway to diagnostic and therapeutic interventions.2004

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Takei Yoshiyuki 竹井謙之

TAKEI Yoshiyuki 竹井謙之

[Book] Hepatology Prectice Vol 2　 NASH・アルコール性肝障害の診療を極める2013

[Journal Article] NASHの最新の知見-基礎と臨床-　（座談会記録）2014

[Journal Article] NAFAD/NASH; 肝発癌に至る病態と対策　（座談会記録）2014