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UENO Takamasa  上野 貴将

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Researcher Number 10322314
Other IDs
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Affiliation *help 2018 : 熊本大学, エイズ学研究センター, 教授
2016 – 2017 : 熊本大学, エイズ学研究センター, 准教授
2007 – 2014 : Kumamoto University, エイズ学研究センター, 准教授
2014 : 熊本大学, 学内共同利用施設等, 准教授
2012 : 熊本大学, 学内共同利用施設等, 准教授
2004 – 2006 : 熊本大学, エイズ学研究センター, 講師
2001 – 2003 : 熊本大学, エイズ学研究センター, 助手
Review Section/Research Field
Principal Investigator
Virology / Biological Sciences / Virology / Medium-sized Section 58:Society medicine, nursing, and related fields
Except Principal Investigator
Biological Sciences / Medium-sized Section 49:Pathology, infection/immunology, and related fields / Infectious disease medicine
Keywords
Principal Investigator
HIV / 感染症 / ウイルス / 細胞傷害性T細胞 / HLA / AIDS / 免疫学 / ワクチン / 細胞障害性T細胞 / 抗原提示 … More / T細胞レセプター / HLAクラスI / 進化 / HIV/AIDS / 感染防御 / CELLULAR IMMUNITY / HIV / 免疫監視 / Nef / 抗原ペプチド / 細胞性免疫 / 発現抑制 / 抗原 / AID S / ファージディスプレイ / 抗ウイルス機能 / 安定性 / 組換え蛋白質 / MHCクラスI / 臨床 / T lymphocyte / 細胞・組織 / ウィルス / T細胞 / ANTIGEN PRESENTATION / エイズウイルス / RECOMBINANT PROTEIN / T cell receptor / 抗ウイルス免疫応答 / CYTOTOXIC T LYMPHOCYTE / T CELL RECEPTOR / 淘汰圧 / 組替え蛋白質 / 抗体 / HIV/AIDS / HLA / ヒト抗ウイルス免疫監視 / SURFACE PLASMON RESONANCE / Nef / ゲノム / エスケープ / antiviral activity / Antigen / 表面プラズモン共鳴 / 免疫回避 … More
Except Principal Investigator
免疫淘汰 / 免疫学 / HTLV-1 / アクセサリータンパク / HIV / ウイルス / スクリーニング / HIV-1細胞障害性T細胞 / HLAクラスI免疫逃避 / 感染症 / Nef / HIV / 抗ウイルス剤 Less
  • Research Projects

    (16results)
  • Research Products

    (119results)
  • Co-Researchers

    (8People)
  •  母子垂直感染後に成長したHIV陽性小児の分子疫学研究Principal InvestigatorOngoing

    • Principal Investigator
      上野 貴将
    • Project Period (FY)
      2018 – 2019
    • Research Category
      Challenging Research (Exploratory)
    • Review Section
      Medium-sized Section 58:Society medicine, nursing, and related fields
    • Research Institution
      Kumamoto University
  •  Dynamic evolution and different pathogenesis of HTLV-1 across multiple continents revealed by next generation sequencing technologyOngoing

    • Principal Investigator
      佐藤 賢文
    • Project Period (FY)
      2018 – 2020
    • Research Category
      Fund for the Promotion of Joint International Research (Fostering Joint International Research (B))
    • Review Section
      Medium-sized Section 49:Pathology, infection/immunology, and related fields
    • Research Institution
      Kumamoto University
  •  Reinvestigating HIV-specific effector cells targeting latent reservoir cellsPrincipal Investigator

    • Principal Investigator
      上野 貴将
    • Project Period (FY)
      2016 – 2017
    • Research Category
      Grant-in-Aid for Challenging Exploratory Research
    • Research Field
      Virology
    • Research Institution
      Kumamoto University
  •  サブサハラアフリカ地域における抗HIV療法下で残存するリザーバーウイルスの解析Principal InvestigatorOngoing

    • Principal Investigator
      上野 貴将
    • Project Period (FY)
      2016 – 2019
    • Research Category
      Grant-in-Aid for Scientific Research (B)
    • Research Field
      Virology
    • Research Institution
      Kumamoto University
  •  抗原変異の著しい病原体に対するHLA分子システムの可塑性と脆弱性Principal Investigator

    • Principal Investigator
      上野 貴将
    • Project Period (FY)
      2013 – 2014
    • Research Category
      Grant-in-Aid for Scientific Research on Innovative Areas (Research in a proposed research area)
    • Review Section
      Biological Sciences
    • Research Institution
      Kumamoto University
  •  Development of anti-HIV agents that exert synergism with host immune pressure

    • Principal Investigator
      KODAMA Eiichi
    • Project Period (FY)
      2012 – 2014
    • Research Category
      Grant-in-Aid for Scientific Research (B)
    • Research Field
      Infectious disease medicine
    • Research Institution
      Tohoku University
  •  A bioinformatics approach toward understanding interplay betweenchronic virus infections and human antiviral immune responsesPrincipal Investigator

    • Principal Investigator
      UENO Takamasa
    • Project Period (FY)
      2011 – 2012
    • Research Category
      Grant-in-Aid for Challenging Exploratory Research
    • Research Field
      Virology
    • Research Institution
      Kumamoto University
  •  Functional adaptation of HIV accessory proteins towardimmune-mediated selective pressurePrincipal Investigator

    • Principal Investigator
      UENO Takamasa
    • Project Period (FY)
      2010 – 2012
    • Research Category
      Grant-in-Aid for Scientific Research (B)
    • Research Field
      Virology
    • Research Institution
      Kumamoto University
  •  CTLの抗ウイルス機能におけるβ2ミクログロブリンの役割Principal Investigator

    • Principal Investigator
      上野 貴将
    • Project Period (FY)
      2009 – 2010
    • Research Category
      Grant-in-Aid for Challenging Exploratory Research
    • Research Field
      Virology
    • Research Institution
      Kumamoto University
  •  Effects of HLA alleles on antiviral activity of T cellsPrincipal Investigator

    • Principal Investigator
      UENO Takamasa
    • Project Period (FY)
      2007 – 2008
    • Research Category
      Grant-in-Aid for Scientific Research (C)
    • Research Field
      Virology
    • Research Institution
      Kumamoto University
  •  ヒト記憶型T細胞のレパートリーが免疫監視機能とその維持に与える影響Principal Investigator

    • Principal Investigator
      上野 貴将
    • Project Period (FY)
      2005 – 2006
    • Research Category
      Grant-in-Aid for Scientific Research on Priority Areas
    • Review Section
      Biological Sciences
    • Research Institution
      Kumamoto University
  •  Effects of HLA-antigen presentation machinery on the antiviral effectiveness of T lymphocytes.Principal Investigator

    • Principal Investigator
      UENO Takamasa
    • Project Period (FY)
      2005 – 2006
    • Research Category
      Grant-in-Aid for Scientific Research (C)
    • Research Field
      Virology
    • Research Institution
      Kumamoto University
  •  ヒト記憶型T細胞のレパートリーが免疫監視機能に及ぼす影響の解明Principal Investigator

    • Principal Investigator
      上野 貴将
    • Project Period (FY)
      2004
    • Research Category
      Grant-in-Aid for Scientific Research on Priority Areas
    • Review Section
      Biological Sciences
    • Research Institution
      Kumamoto University
  •  HIV-1の細胞傷害性T細胞からの逃避機序の研究

    • Principal Investigator
      滝口 雅文
    • Project Period (FY)
      2003
    • Research Category
      Grant-in-Aid for Scientific Research on Priority Areas
    • Review Section
      Biological Sciences
    • Research Institution
      Kumamoto University
  •  HIV-1の細胞傷害性T細胞からの逃避機序の研究

    • Principal Investigator
      TAKIGUCHI Masafumi
    • Project Period (FY)
      2002
    • Research Category
      Grant-in-Aid for Scientific Research on Priority Areas
    • Review Section
      Biological Sciences
    • Research Institution
      Kumamoto University
  •  KINETIC ANALYSIS OF ANTIGEN-PRESENTATION OF HIV-INFECTED CELLS USING SOLUBLE T CELL RECEPTORSPrincipal Investigator

    • Principal Investigator
      UENO Takamasa
    • Project Period (FY)
      2001 – 2002
    • Research Category
      Grant-in-Aid for Scientific Research (C)
    • Research Field
      Virology
    • Research Institution
      KUMAMOTO UNIVERSITY

All 2018 2017 2016 2015 2014 2013 2012 2011 2010 2009 2008 2007 2006 2005 2004 Other

All Journal Article Presentation Book

  • [Book] HIV感染症-宿主側の防衛因子の役割-「HIVコントロールにおけるCTLの役割」血液フロンティア2008

    • Author(s)
      上野貴将、本園千尋
    • Publisher
      医薬ジャーナル社
    • Data Source
      KAKENHI-PROJECT-19590479
  • [Book] アイソトープのヒト免疫研究への活用細胞工学別冊実験プロトコールシリーズ2007

    • Author(s)
      上野貴将
    • Publisher
      秀潤社
    • Data Source
      KAKENHI-PROJECT-19590479
  • [Journal Article] Resistance of Major Histocompatibility Complex Class B (MHC-B) to Nef-Mediated Downregulation Relative to that of MHC-A Is Conserved among Primate Lentiviruses and Influences Antiviral T Cell Responses in HIV-1-Infected Individuals2018

    • Author(s)
      F Mwimanzi, M Toyoda, M Mahiti, J Mann, J Martin, D Bangsberg, M Brockman, P Goulder, F Kirchhoff, Z Brumme, T Ndung’u, T Ueno
    • Journal Title

      Journal of Virology

      Volume : 92

    • DOI
      10.1128/jvi.01409-17
    • Peer Reviewed / Open Access / Int'l Joint Research
    • Data Source
      KAKENHI-PROJECT-16H05822, KAKENHI-PROJECT-16K15284, KAKENHI-PROJECT-16K19141
  • [Journal Article] Conserved Vδ1 binding geometry in a setting of locus-disparate pHLA recognition by δ/αβTCRs: insight into recognition of HIV peptides by TCR2017

    • Author(s)
      ③Yi Shi, Ai Kawana-Tachikawa, Feng Gao, Jianxun Qi, Chuansheng Liu, Jia Gao, Hao Cheng, Takamasa Ueno, Aikichi Iwamoto, George Gao
    • Journal Title

      Journal of Virology

      Volume : 91

    • Int'l Joint Research / Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-16K15284
  • [Journal Article] Identification of two unique naturally occurring Vpr sequence polymorphisms associated with clinical parameters in HIV-1 chronic infection2017

    • Author(s)
      Kamori Doreen、Hasan Zafrul、Ohashi Jun、Kawana-Tachikawa Ai、Gatanaga Hiroyuki、Oka Shinichi、Ueno Takamasa
    • Journal Title

      Journal of Medical Virology

      Volume : 89 Pages : 123-129

    • DOI
      10.1002/jmv.24612
    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-16H05822, KAKENHI-PROJECT-16K15284
  • [Journal Article] HIV-1 Tat and Viral Latency: What We Can Learn from Naturally Occurring Sequence Variations2017

    • Author(s)
      Kamori Doreen、Ueno Takamasa
    • Journal Title

      Frontiers in Microbiology

      Volume : 8 Pages : 80-80

    • DOI
      10.3389/fmicb.2017.00080
    • Peer Reviewed / Open Access
    • Data Source
      KAKENHI-PROJECT-16H05822, KAKENHI-PROJECT-16K15284
  • [Journal Article] Relative resistance of HLA-B to down-regulation by naturally occurring HIV-1 Nef sequences2016

    • Author(s)
      61.Macdonald Mahiti, Mako Toyoda, Xiaofei Jia, Xiaomei T. Kuang, Francis Mwimanzi, Philip Mwimanzi, Bruce D Walker, Yong Xiong, Zabrina L Brumme, Mark A Brockman, Takamasa Ueno
    • Journal Title

      mBio

      Volume : 7

    • Open Access / Int'l Joint Research / Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-16H05822
  • [Journal Article] Relative resistance of HLA-B to down-regulation by naturally occurring HIV-1 Nef sequences2016

    • Author(s)
      Macdonald Mahiti, Mako Toyoda, Xiaofei Jia, Xiaomei T. Kuang, Francis Mwimanzi, Philip Mwimanzi, Bruce D Walker, Yong Xiong, Zabrina L Brumme, Mark A Brockman, Takamasa Ueno
    • Journal Title

      mBio

      Volume : 7

    • DOI
      10.1128/mbio.01516-15
    • Peer Reviewed / Open Access / Int'l Joint Research
    • Data Source
      KAKENHI-PROJECT-16K15284
  • [Journal Article] Clonotypically similar hybrid αβ TCRs can exhibit markedly different surface expression, antigen specificity and cross-reactivity.2015

    • Author(s)
      Chihiro Motozono, John S. Bridgeman, David A. Price, Andrew K. Sewell ,Takamasa Ueno
    • Journal Title

      Clinical and Experimental Immunology

      Volume : in press

    • DOI
      10.1111/cei.12610
    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-24390254
  • [Journal Article] Modest Attenuation of HIV-1 Vpu Alleles Derived from Elite Controller Plasma.2015

    • Author(s)
      Chen J, Tibroni N, Sauter D, Galaski J, Miura T, Alter G, Mueller B, Haller C, Walker BD, Kirchhoff F, Brumme ZL, Ueno T, Fackler OT.
    • Journal Title

      PLoS One

      Volume : 10 Issue : 3 Pages : e0120434

    • Publisher
      Public Library of Science
    • DOI
      10.1371/journal.pone.0120434
    • Year and Date
      2015-03-20
    • Language
      English
    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-24390254
  • [Journal Article] Selection of TI8-8V mutant associated with long-term control of HIV-1 by cross-reactive HLA-B*51:01-restricted cytotoxic T cells.2014

    • Author(s)
      Nozomi Kuse, Tomohiro Akahoshi, Hiroyuki Gatanaga, Takamasa Ueno, Shinichi Oka, Masafumi Takiguchi
    • Journal Title

      Journal of Immunology

      Volume : 193 Pages : 4814-4822

    • DOI
      10.4049/jimmunol.1401419
    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-24390254
  • [Journal Article] Cross-reactivity analysis of T cell receptors specific for overlapping HIV-1 Nef epitopes of different lengths.2014

    • Author(s)
      Chihiro Motozono, Masaru Yokoyama, Hironori Sato, Takamasa Ueno
    • Journal Title

      Microbes and Infection

      Volume : 16 Pages : 320-327

    • DOI
      10.1016/j.micinf.2013.12.005
    • Peer Reviewed / Acknowledgement Compliant
    • Data Source
      KAKENHI-PUBLICLY-25133706
  • [Journal Article] Impaired Nef function is associated with early control of HIV-1 viremia.2014

    • Author(s)
      Kuang XT, Li X, Anmole G, Mwimanzi P, Shahid A, Le AQ, Chong L, Qian H, Miura T, Markle T, Baraki B, Connick E, Daar ES, Jessen H, Kelleher AD, Little S, Markowitz M, Pereyra F, Rosenberg ES, Walker BD, Ueno T, Brumme ZL, Brockman MA.
    • Journal Title

      Journal of Virology

      Volume : 88 Pages : 10200-10213

    • DOI
      10.1128/jvi.01334-14
    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-24390254
  • [Journal Article] Role of host immune responses in sequence variability of HIV-1 Vpu2014

    • Author(s)
      Zafrul Hasan, Doreen Kamori and Takamasa Ueno
    • Journal Title

      World Journal of Immunology

      Volume : 4 Pages : 107-115

    • DOI
      10.5411/wji.v4.i2.107
    • Peer Reviewed / Open Access / Acknowledgement Compliant
    • Data Source
      KAKENHI-PROJECT-24390254, KAKENHI-PUBLICLY-25133706
  • [Journal Article] Peptide-dependent Conformational Fluctuation Determines the Stability of the Human Leukocyte Antigen Class I Complex2014

    • Author(s)
      Saeko Yanaka, Takamasa Ueno, Yi Shi, Jianxun Gi, George F. Gao, Kouhei Tsumoto, and Kenji Sugase
    • Journal Title

      The Journal of Biological Chemistry

      Volume : 268 Pages : 24680-90

    • DOI
      10.1074/jbc.m114.566174
    • Peer Reviewed / Open Access / Acknowledgement Compliant
    • Data Source
      KAKENHI-PROJECT-13J09564, KAKENHI-PROJECT-24000011, KAKENHI-PROJECT-24390254, KAKENHI-PROJECT-25000006, KAKENHI-PUBLICLY-25133706, KAKENHI-PROJECT-25249115
  • [Journal Article] HLA class I down-regulation by HIV-1 Nef: What might we learn from natural sequence variants?2013

    • Author(s)
      Philip Mwimanzi, Tristan J. Markle,Takamasa Ueno, Mark A. Brockman
    • Journal Title

      Viruses

      Volume : 4 Pages : 1711-1730

    • DOI
      10.3390/v4091711
    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-22390089, KAKENHI-PROJECT-23659232, KAKENHI-PROJECT-24390254
  • [Journal Article] Attenuation of multiple Nef functions in HIV-1 elite controllers.2013

    • Author(s)
      Philip Mwimanzi, Tristan J Markle,Eric Martin, Yoko Ogata, Xiaomei TKuang, Michiyo Tokunaga, MacdonaldMahiti, Florencia Pereyra, ToshiyukiMiura, Bruce D Walker, Zabrina L Brumme,Mark A Brockman and *Takamasa Ueno
    • Journal Title

      Retrovirology

      Volume : 10 Pages : 1-1

    • DOI
      10.1186/1742-4690-10-1
    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-22390089, KAKENHI-PROJECT-23659232, KAKENHI-PROJECT-24390254
  • [Journal Article] Dynamic range of Nef functions in chronic HIV-1 infection2013

    • Author(s)
      Philip Mwimanzi, Tristan J Markle,Yoko Ogata, Eric Martin, MichiyoTokunaga, Macdonald Mahiti, Xiaomei TKuang, Bruce D Walker, Zabrina L Brumme,Mark A Brockman and *Takamasa Ueno
    • Journal Title

      Virology

      Volume : 439 Pages : 74-80

    • DOI
      10.1016/j.virol.2013.02.005
    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-22390089, KAKENHI-PROJECT-23659232, KAKENHI-PROJECT-24390254
  • [Journal Article] CD8+ T cell cross-reactivity profiles and HIV-1 immune escape towards an HLA-B35-restricted immunodominant Nef epitope.2013

    • Author(s)
      C. Motozono, J. Miles, Z. Hasan, H. Gatanaga, S. Meribe, D. Price, S. Oka, A. Sewell, T. Ueno
    • Journal Title

      PLoS ONE

      Volume : 8

    • DOI
      10.1371/journal.pone.0066152
    • Peer Reviewed
    • Data Source
      KAKENHI-PUBLICLY-25133706
  • [Journal Article] Minor contribution of HLA class I-associated selective pressure to the variability of HIV-1 accessory protein Vpu.2012

    • Author(s)
      Zafrul Hasan, Jonathan M Carlson,Hiroyuki Gatanaga, Anh Q. Le, ChansonJ Brumme, Shinichi Oka, Zabrina LBrumme, *Takamasa Ueno
    • Journal Title

      Biochem. Biophys. Res. Comm.

      Volume : 421 Pages : 291-295

    • DOI
      10.1016/j.bbrc.2012.04.002
    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-22390089, KAKENHI-PROJECT-24390254
  • [Journal Article] Effects of naturally-arising HIV Nef mutations on cytotoxic T lymphocyte recognition and Nefs functionality in primary macrophages2011

    • Author(s)
      Philip Mwimanzi, Zafrul Hasan, RanyaHassan, Shinya Suzu, Masafumi Takiguchiand*TakamasaUeno
    • Journal Title

      Retrovirology

      Volume : 8 Pages : 50-50

    • DOI
      10.1186/1742-4690-8-50
    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-22390089, KAKENHI-PROJECT-23659232
  • [Journal Article] Theidentification of a small moleculecompound that reduces HIV-1Nef-mediated viral infectivityenhancement2011

    • Author(s)
      Nopporn Chutiwitoonchai, MasateruHiyoshi, Philip Mwimanzi, TakamasaUeno, Akio Adachi, Hirotaka Ode,Hironori Sato, Oliver T. Fackler,Seiji Okada, Shinya Suzu
    • Journal Title

      PLoS ONE

      Volume : 6(11)

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-22390089
  • [Journal Article] Differentin vivo effects of HIV-1immunodominant epitope-specific CTLson selection of escape mutant viruses2010

    • Author(s)
      Koizumi H, Hashimoto M, Fujiwara M,Murakoshi H, Chikata T, Borghan MA,Hachiya A, Kawashima Y, Takata H, UenoT, Oka S, Takiguchi M
    • Journal Title

      Journal of Virology

      Volume : 84 Pages : 5508-5519

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-22390089
  • [Journal Article] Naturallyarising HIV-1 Nef variants conferringescape from cytotoxic T lymphocytesinfluence viral entry co-receptorexpression and susceptibility tosuperinfection2010

    • Author(s)
      Philip Mwimanzi, Zafrul Hasan, MichiyoTokunaga, Hiroyuki Gatanaga, Shinichi Oka, *Takamasa Ueno
    • Journal Title

      Biochem. Biophys. Res.Comm

      Volume : 403 Pages : 422-427

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-22390089
  • [Journal Article] Dynamic interplay between viral adaptation and immune recognition during HIV-1 infection.2010

    • Author(s)
      Chihiro Motozono, Philip Mwimanzi, Takamasa Ueno
    • Journal Title

      Protein & Cell

      Volume : 1 Pages : 514-519

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-21659115
  • [Journal Article] Dynamicinterplay between viral adaptation andimmune recognition during HIV-1infection2010

    • Author(s)
      Chihiro Motozono, Philip Mwimanzi,*Takamasa Ueno
    • Journal Title

      Protein & Cell

      Volume : 1 Pages : 514-519

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-22390089
  • [Journal Article] Failure of effectorfunction of human CD8+ T cells inNOD/SCID/JAK3-/- immunodeficient micetransplanted with human CD34+hematopoietic stem cells2010

    • Author(s)
      Yoshinori Sato, Hiroshi Takata, NaokiKobayashi, Sayaka Nagata, NaomiNakagata, Takamasa Ueno, MasafumiTakiguchi
    • Journal Title

      PLoS ONE

      Volume : 5 Issue : 10

    • Publisher
      Public Library of Science
    • DOI
      10.1371/journal.pone.0013109
    • Year and Date
      2010-10-01
    • Language
      English
    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-22390089
  • [Journal Article] Impact of intrinsic cooperative thermodynamics of peptide-MHC complexes on antiviral acivity of HIV-specific CTL2009

    • Author(s)
      C Motozono, S Yanaka, K Tsumoto, M Takiguchi, T Ueno
    • Journal Title

      J.Immunol 182

      Pages : 5528-5536

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-21659115
  • [Journal Article] Strong ability of Nef-specific CD4+ cytotoxic T cells to suppress HIV-1 replication in HIV-1-infected CD4+T cells and macrophages2009

    • Author(s)
      Zheng N, Fujiwara M, Ueno T, Oka S, Takiguchi M
    • Journal Title

      J.Virol 83

      Pages : 7668-7677

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-21659115
  • [Journal Article] Impact of intrinsic cooperative thermodynamics of peptide-MHC complexes on antiviral acivity of HIV-specific CTL2009

    • Author(s)
      Chihiro Motozono, Saeko Yanaka, Kouhei Tsumoto, Masafumi Takiguchi, Takamasa Ueno
    • Journal Title

      Journal of Immunology 182

      Pages : 5528-5536

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-19590479
  • [Journal Article] Dys-regulated activation of a Src tyroine kinase Hck at the Golgi disturbs N-glycosylation of a cytokine receptor Fms2009

    • Author(s)
      R Hassan, S Suzu, M Hiyoshi, N T-Makise, T Ueno, T Agatsuma, H Akari, J Komano, Y Takebe, K Motoyoshi, S Okada
    • Journal Title

      J Cell Physiol 221

      Pages : 458-468

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-21659115
  • [Journal Article] CTL-mediated selective pressure influences dynamic evolution and pathogenic functions of HIV-1 Nef2008

    • Author(s)
      Takamasa Ueno, Chihiro Motozono, Sachi Dohki, Philip Mwimanzi, Susanne Rauch, Oliver T. Fackler, Shinichi, Oka, Masafumi Takiguchi
    • Journal Title

      Journal of Immunology 180

      Pages : 1107-1116

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-19590479
  • [Journal Article] Determination of a major histocompatibility complex class I restricting simian immunodeficiency virus Gag241-249 epitope2008

    • Author(s)
      Tetsuo Tsukamoto, Sachi Dohki, Takamasa Ueno, Miki Kawada, Akiko Takeda, Michio Yasunami, Taeko Naruse, Akinori Kimura, Masafumi Takiguchi, and Tetsuro Matano
    • Journal Title

      AIDS 22

      Pages : 993-994

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-19590479
  • [Journal Article] CTL-mediated selective pressure influences dynamic evolution and pathogenic functions of HIV-1 Nef2008

    • Author(s)
      Takamasa Ueno
    • Journal Title

      Journal of Immunology 180

      Pages : 1107-1116

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-19590479
  • [Journal Article] Cytotoxic T lymphocyte-mediated selective pressure influences dynamic evolution and pathogenic functions of HIV-1 Nef2008

    • Author(s)
      Takamasa Ueno
    • Journal Title

      Journal of Immunology 180

      Pages : 1107-1116

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-19590479
  • [Journal Article] Altering effects of antigenic variations in HIV-1 on antiviral effectiveness of HIV-specific CTLs.2007

    • Author(s)
      Takamasa Ueno, et al.
    • Journal Title

      Journal of Immunology (in press)

    • Data Source
      KAKENHI-PROJECT-17590419
  • [Journal Article] Altering effects of antigenic variations in HIV-1 on antiviral effectiveness of HIV-specific CTLs2007

    • Author(s)
      Takamasa Ueno, et al.
    • Journal Title

      The Journal of Immunology 178

      Pages : 5513-5523

    • Description
      「研究成果報告書概要(欧文)」より
    • Data Source
      KAKENHI-PROJECT-17590419
  • [Journal Article] Altering effects of antigenic variations of HIV-1 on the antiviral effectiveness of HIV-specific CTLs2007

    • Author(s)
      Takamasa Ueno, et al.
    • Journal Title

      The Journal of Immunology 178

      Pages : 5513-5523

    • Description
      「研究成果報告書概要(和文)」より
    • Data Source
      KAKENHI-PROJECT-17590419
  • [Journal Article] Altering effects of antigenic variations in HIV-1 on antiviral effectiveness of HIV-specific CTLs2007

    • Author(s)
      Takamasa Ueno, Yuka Idegami, Chihiro Motozono, Shinichi, Oka, Masafumi Takiguchi
    • Journal Title

      Journal of Immunology 178

      Pages : 5513-5523

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-19590479
  • [Journal Article] Altering effects of antigenic variations in HIV-1 on antiviral effectiveness of HIV-specific CTLs2007

    • Author(s)
      Takamasa Ueno
    • Journal Title

      Journal of Immunology 178

      Pages : 5513-5523

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-19590479
  • [Journal Article] Altering effects of antigenic variations in HIV-1 on antiviral effectiveness of HIV-specific CTLs.2007

    • Author(s)
      Takamasa Ueno, et al.
    • Journal Title

      Journal of Immunology (in press)

    • Data Source
      KAKENHI-PROJECT-17047034
  • [Journal Article] HLAアリル多型性とHIV感染症2006

    • Author(s)
      上野貴将
    • Journal Title

      診断と治療 94(12)

      Pages : 121-124

    • Description
      「研究成果報告書概要(和文)」より
    • Data Source
      KAKENHI-PROJECT-17590419
  • [Journal Article] クラスI MHC拘束性抗原提示機構2005

    • Author(s)
      上野貴将
    • Journal Title

      臨床免疫学(上) 63・4

      Pages : 304-308

    • Data Source
      KAKENHI-PROJECT-17590419
  • [Journal Article] Cytotoxic T lymphocyte-mediated immune responses to HIV.2005

    • Author(s)
      Takamasa Ueno, et al.
    • Journal Title

      The Journal of AIDS Research 7(3)

      Pages : 155-160

    • Description
      「研究成果報告書概要(欧文)」より
    • Data Source
      KAKENHI-PROJECT-17590419
  • [Journal Article] Cytotoxic T lymphocyte-mediated immune responses to HIV.2005

    • Author(s)
      Takamasa Ueno, Masafumi Takiguchi
    • Journal Title

      The Journal of AIDS Research 7・3

      Pages : 155-160

    • Data Source
      KAKENHI-PROJECT-17590419
  • [Journal Article] Cytotoxic T lymphocyte-mediated immune responses to HIV.2005

    • Author(s)
      Takamasa Ueno, Masafumi Takiguchi
    • Journal Title

      The Journal of AIDS Research 7・3

      Pages : 155-160

    • Data Source
      KAKENHI-PROJECT-17047034
  • [Journal Article] HIVに対する細胞傷害性T細胞の免疫応答2005

    • Author(s)
      上野貴将ら
    • Journal Title

      The Journal of AIDS Research 7(3)

      Pages : 155-160

    • Description
      「研究成果報告書概要(和文)」より
    • Data Source
      KAKENHI-PROJECT-17590419
  • [Journal Article] Functionally impaired HIV-specific CD8 T cells show high-affinity T cell receptor-ligand interactions.2004

    • Author(s)
      Takamasa Ueno
    • Journal Title

      J.Immunol. 173

      Pages : 5451-5457

    • Data Source
      KAKENHI-PROJECT-16043244
  • [Journal Article] Reconstitution of anti-HIV effector functions of primary human CD8 T lymphocytes by transfer of HIV-specific αβ TCR genes.2004

    • Author(s)
      Takamasa Ueno
    • Journal Title

      J.Immunol. 34・12

      Pages : 3379-3388

    • Data Source
      KAKENHI-PROJECT-16043244
  • [Presentation] MHCとHIV-1 Nefとの相互作用と免疫制御への影響2017

    • Author(s)
      上野貴将
    • Organizer
      第26回日本組織適合性学会大会
    • Invited
    • Data Source
      KAKENHI-PROJECT-16K15284
  • [Presentation] Relative resistance of MHC-B to Nef-mediated downregulation is conserved among lentiviruses and correlates with reduced viral loads in HIV-1-infected patient2017

    • Author(s)
      Francis Mwimanzi, Macdonald Mahiti, Mako Toyoda, Frank Kirchhoff, Thumbi Ndung’u, Takamasa Ueno
    • Organizer
      第31回日本エイズ学会学術集会・総会
    • Data Source
      KAKENHI-PROJECT-16K15284
  • [Presentation] Relative resistance of HLA-B for downregulation by Nef is a fundamental property across lentiviral lineage2017

    • Author(s)
      Francis Mwimanzi, Macdonald Mahiti, Toyoda Mako, Jaclyn K Mann, Thumbi Ndung’u, Takamasa Ueno
    • Organizer
      9th International AIDS Society Conference on HIV Sciences
    • Int'l Joint Research
    • Data Source
      KAKENHI-PROJECT-16K15284
  • [Presentation] MHCとHIV-1 Nefとの相互作用と免疫制御への影響2017

    • Author(s)
      上野貴将
    • Organizer
      第26回日本組織適合性学会大会
    • Invited
    • Data Source
      KAKENHI-PROJECT-16H05822
  • [Presentation] Relative resistance of HLA-B for downregulation by Nef is a fundamental property across lentiviral lineage2017

    • Author(s)
      Francis Mwimanzi, Macdonald Mahiti, Toyoda Mako, Jaclyn K Mann, Thumbi Ndung’u, Takamasa Ueno
    • Organizer
      9th International AIDS Society Conference on HIV Sciences
    • Int'l Joint Research
    • Data Source
      KAKENHI-PROJECT-16H05822
  • [Presentation] Poor disease Prognostication by a naturally-arising polymorphism within functional region of HIV-1 Nef2014

    • Author(s)
      Stanley M, Hasan Z, Gatanaga H, Miura T, Kawana-Tachikawa A, Iwamoto A, Oka S, Takamasa Ueno
    • Organizer
      Conference on Retroviruses and Opportunistic Infections
    • Place of Presentation
      ボストン・アメリカ
    • Data Source
      KAKENHI-PROJECT-24390254
  • [Presentation] and the Acute HIVand International HIV Controllersstudy group. Reduced HIV-1 NefFunction in Acute/Early Individualswho become Viremic Controllers2013

    • Author(s)
      X. Kuang, A Le, P Mwimanzi, T Markle,R Danroth, T Ueno, T Miura, B Walker,Z Brumme, M Brockman
    • Organizer
      20thConference on Retroviruses andOpportunistic Infections (CROI)
    • Place of Presentation
      Georgia World Congress Center, Atlanta,USA
    • Data Source
      KAKENHI-PROJECT-22390089
  • [Presentation] Effects of naturally occurring polymorphisms in functional domains of HIV-1 nef on in vivo disease progression2013

    • Author(s)
      Stanley M, Hasan Z, Gatanaga H, Miura T, Kawana-Tachikawa A, Iwamoto A, Oka S, Takamasa Ueno
    • Organizer
      The 27th Annual meeting of Japanese Society for AIDS Research
    • Place of Presentation
      熊本
    • Data Source
      KAKENHI-PROJECT-24390254
  • [Presentation] Reduced HIV-1 Nef Function in Acute/Early Individuals who become Viremic Controllers.2013

    • Author(s)
      X. Kuang, A Le, P Mwimanzi, T Markle, R Danroth, T Ueno, T Miura, B Walker, Z Brumme, M Brockman, and the Acute HIV and International HIV Controllers study group.
    • Organizer
      The 20th Conference on Retroviruses and Opportunistic Infections (CROI)
    • Place of Presentation
      Atlanta, USA
    • Data Source
      KAKENHI-PROJECT-24390254
  • [Presentation] HLA class I-mediatedsequence polymorphism in HIV-1accessory protein Vpu2012

    • Author(s)
      Zafrul Hasan, J. Carlson, H. Gatanaga,A. Le, C. Brumme, S. Oka, Z. Brumme,Takamasa Ueno
    • Organizer
      The 13thKUMAMOTO AIDS Seminar and GCOE JointInternational Symposium
    • Place of Presentation
      Hotel NikkoKumamoto and Aso Resort GrandvrioHotel, Kumamoto, Japan
    • Data Source
      KAKENHI-PROJECT-22390089
  • [Presentation] HIV-1 immune escape andcross-reactivity profiles ofvirus-specific cytotoxic Tlymphocytes, YIS-A Session II2012

    • Author(s)
      Chihiro Motozono, John J. Miles,Zafrul Hasan, Hiroyuki Gatanaga,Meribe Stanley, Shinichi Oka, MasaakiMiyazawa, Andrew K. Sewell, TakamasaUeno
    • Organizer
      13thKumamoto AIDS Seminar Global COE JointInternational Symposium
    • Place of Presentation
      Aso ResortGRANDVRIO, Kumamoto, Japan
    • Data Source
      KAKENHI-PROJECT-22390089
  • [Presentation] Functional impairment ofHIV-1 Nef in elite controllers and itscorrelation with immune-mediatedselective pressure2012

    • Author(s)
      T. Ueno
    • Organizer
      13th Kumamoto AIDSSeminar Global COE Joint InternationalSymposium
    • Place of Presentation
      Aso Resort GrandvrioHotel,Kumamoto, Japan
    • Data Source
      KAKENHI-PROJECT-22390089
  • [Presentation] Modulation of HIV-1Nef-mediated HLA class Idown-regulation activity duringdisease progression2012

    • Author(s)
      M. Mahiti, P. Mwimanzi, Y. Ogata, M.Tokunaga, B. Walker, Z. Brumme, M.Brockman, T. Ueno
    • Organizer
      13th KumamotoAIDS seminar
    • Place of Presentation
      Aso Resort GrandiovrioHotel, Kumamoto, Japan
    • Data Source
      KAKENHI-PROJECT-22390089
  • [Presentation] HLA-B35 拘束性 HIV 特異的 TCR は野生型抗原に高い特異性を有する、学術賞ならびに学術奨励賞候補口演2012

    • Author(s)
      本園千尋、John J. Miles、宮澤正顯、上野貴将、Andrew K. Sewell
    • Organizer
      第21回組織適合性学会大会
    • Place of Presentation
      明治大学、東京
    • Data Source
      KAKENHI-PROJECT-22390089
  • [Presentation] Impact of HLA class I-driven geneticvariability in HIV-1 accessory genevpu2012

    • Author(s)
      Zafrul Hasan, J. Carlson, H. Gatanaga,A. Le, S. Oka, Z. Brumme, Takamasa Ueno
    • Organizer
      COLD SPRING HARBOR ASIACONFERENCES: Frontiers of Immunologyin Health and Disease
    • Place of Presentation
      Suzhou DushuLake Conference Center, China
    • Data Source
      KAKENHI-PROJECT-22390089
  • [Presentation] HLA-B35拘束性HIV特異的TCRは野生型抗原に高い特異性を有する2012

    • Author(s)
      本園千尋、John J. Miles、宮澤正顯、上野貴将、Andrew K. Sewell
    • Organizer
      第21回組織適合性学会大会
    • Place of Presentation
      東京
    • Data Source
      KAKENHI-PROJECT-24390254
  • [Presentation] Modulation of HIV-1 Nef-mediated HLA class I down-regulation activity during disease progression.2012

    • Author(s)
      M. Mahiti, P. Mwimanzi, Y. Ogata, M. Tokunaga, B. Walker, Z. Brumme, M. Brockman, T. Ueno
    • Organizer
      13th Kumamoto AIDS seminar
    • Place of Presentation
      熊本
    • Data Source
      KAKENHI-PROJECT-24390254
  • [Presentation] Functional impairment of HIV-1 Nef in elite controllers and its correlation with immune-mediated selective pressure.2012

    • Author(s)
      T. Ueno
    • Organizer
      13th Kumamoto AIDS Seminar Global COE Joint International Symposium
    • Place of Presentation
      熊本
    • Data Source
      KAKENHI-PROJECT-24390254
  • [Presentation] HIV-1 immune escape and cross-reactivity profiles of virus-specific cytotoxic T lymphocytes, YIS-A Session II.2012

    • Author(s)
      Chihiro Motozono, John J. Miles, Zafrul Hasan, Hiroyuki Gatanaga, Meribe Stanley, Shinichi Oka, Masaaki Miyazawa, Andrew K. Sewell, Takamasa Ueno.
    • Organizer
      The13th Kumamoto AIDS Seminar Global COE Joint International Symposium
    • Place of Presentation
      熊本
    • Data Source
      KAKENHI-PROJECT-24390254
  • [Presentation] Genetic and functional analyses of HIV-1 Nef in elite controllers.2012

    • Author(s)
      Zafrul Hasan, J. Carlson, H. Gatanaga, A. Le, C. Brumme, S. Oka, Z. Brumme, Takamasa Ueno.
    • Organizer
      第60回日本ウイルス学会学術集会
    • Place of Presentation
      大阪
    • Data Source
      KAKENHI-PROJECT-24390254
  • [Presentation] The impact of a single amino acid difference in CDR3a on TCR ab cross-reactivity.2012

    • Author(s)
      Chihiro Motozono, John S. Bridgeman, Masaaki Miyazawa, Andrew K. Sewell and Takamasa Ueno.
    • Organizer
      第41回日本免疫学会総会・学術集会
    • Place of Presentation
      神戸
    • Data Source
      KAKENHI-PROJECT-24390254
  • [Presentation] The impact of a single amino acid difference in CDR3・onTCR・・・cross-reactivity、ワークショップ 32 ヒト免疫、2012

    • Author(s)
      Chihiro Motozono, John S. Bridgeman,Masaaki Miyazawa, Andrew K. Sewell andTakamasa Ueno
    • Organizer
      第41回日本免疫学会総会・学術集会
    • Place of Presentation
      神戸国際会議場、兵庫
    • Data Source
      KAKENHI-PROJECT-22390089
  • [Presentation] Nef のウイルスレセプター発現低下機能と病態2012

    • Author(s)
      緒方陽子、Philip Mwimanzi、李小光、徳永美知代、Tristan Markle、三浦聡之、Bruce Walker 、Zabrina Brumme 、MarkBrockman、上野貴将
    • Organizer
      第26回日本エイズ学会学術集会・総会
    • Place of Presentation
      慶應義塾大学日吉キャンパス(神奈川)
    • Data Source
      KAKENHI-PROJECT-23659232
  • [Presentation] Modulation of HIV-1Nef-mediated HLA class Idown-regulation activity duringdisease progression2012

    • Author(s)
      M. Mahiti, P. Mwimanzi, Y. Ogata, M.Tokunaga, B. Walker, Z. Brumme, M.Brockman, T. Ueno
    • Organizer
      13th KumamotoAIDS seminar Aso Resort GrandiovrioHotel
    • Place of Presentation
      Kumamoto, Japan
    • Data Source
      KAKENHI-PROJECT-23659232
  • [Presentation] HIV-1 Nef の遺伝子多型性と機能的可塑性2012

    • Author(s)
      上野貴将
    • Organizer
      第14回白馬シンポジウムin 京都
    • Place of Presentation
      京都市国際交流会館
    • Data Source
      KAKENHI-PROJECT-23659232
  • [Presentation] Impact of HLA class I-drivengenetic variability in HIV-1 accessorygenes in Japanese sequences. KeystoneSymposia HIV Evolution2011

    • Author(s)
      Zafrul Hasan, J. Carlson, H. Gatanaga,A. Le, C. Brumme, S. Oka, Z. Brumme, T.Ueno
    • Organizer
      Genomics andPathogenesis
    • Place of Presentation
      Whistler, Canada
    • Data Source
      KAKENHI-PROJECT-22390089
  • [Presentation] Impairment of virioninfectivity by nef alleles from HIVelite controllers2011

    • Author(s)
      Philip Mwimanzi, Tristan Markle,Michiyo Tokunaga, Toshiyuki Miura,Eric Martin, Florencia Pereyra, BruceWalker, Zabrina Brumme, Mark Brockman,Takamasa Ueno
    • Organizer
      Nef activity inenhancement of virion infectivity isimpaired in HIV elite controllers
    • Place of Presentation
      XV,International Congress of Virology,Sapporo Convention Center,Sapporo,Japan
    • Data Source
      KAKENHI-PROJECT-22390089
  • [Presentation] Impairment of virioninfectivity by nef alleles from HIVelite controllers2011

    • Author(s)
      Philip Mwimanzi, Tristan Markle,Michiyo Tokunaga, Toshiyuki Miura,Eric Martin, Florencia Pereyra, BruceWalker, Zabrina Brumme, Mark Brockman,Takamasa Ueno
    • Organizer
      Keystone SymposiaHIV Evolution
    • Place of Presentation
      Genomics andPathogenesis, Canada
    • Data Source
      KAKENHI-PROJECT-22390089
  • [Presentation] Effect of HLA class I-mediatedselective pressure on HIV-1 accessorygenes2011

    • Author(s)
      Zafrul Hasan, J. Carlson, H. Gatanaga,A. Le, C. Brumme, S. Oka, Z. Brumme, T.Ueno
    • Organizer
      International Union ofMicrobiological Societies 2011Congress: Virus and host response
    • Place of Presentation
      Sapporo Convention Center, Sapporo,Japan
    • Data Source
      KAKENHI-PROJECT-22390089
  • [Presentation] Thecross-reactivity footprints ofHIV-specific CTLs2011

    • Author(s)
      Chihiro Motozono, John J. Miles, LindaWooldridge, David A. Price, TakamasaUeno, Andrew K. Sewell
    • Organizer
      12th Kumamoto AIDSSeminar and GCOE Joint InternationalSymposium
    • Place of Presentation
      Hotel Nikko Kumamoto and Aso Resort Grandvrio Hotel, Kumamoto,Japan
    • Data Source
      KAKENHI-PROJECT-22390089
  • [Presentation] Impairment ofviral replication capacity by nefalleles from HIV elite controllers.Frontiers of Retrovirology2011

    • Author(s)
      Philip Mwimanzi, Tristan Markle,Michiyo Tokunaga, Toshiyuki Miura,Eric Martin, Florencia Pereyra, BruceWalker, Zabrina Brumme, MarkBrockman,Takamasa Ueno
    • Organizer
      Complexretroviruses, retroelements and theirhosts
    • Place of Presentation
      Amsterdam, Netherlands
    • Data Source
      KAKENHI-PROJECT-22390089
  • [Presentation] Impaired viralinfectivity and viral replicationcapacity by nef alleles from HIV elitecontrollers2011

    • Author(s)
      Philip Mwimanzi, Tristan Markle,Michiyo Tokunaga, Toshiyuki Miura,Eric Martin, Florencia Pereyra, BruceWalker, Zabrina Brumme, Mark Brockman,Takamasa Ueno
    • Organizer
      25th Annual Meeting ofJapanese Society for AIDS Research
    • Place of Presentation
      Tokyo Hyatt Regency, Tokyo, Japan
    • Data Source
      KAKENHI-PROJECT-22390089
  • [Presentation] Impact of HLA class I-drivengenetic variability in HIV-1 accessorygenes2011

    • Author(s)
      Zafrul Hasan, J. Carlson, H. Gatanaga,A. Le, C. Brumme, S. Oka, Z. Brumme, T.Ueno
    • Organizer
      2011 The Annual Meeting of theJapanese Society for Immunology
    • Place of Presentation
      Chiba,Makuhari Messe, Japan
    • Data Source
      KAKENHI-PROJECT-22390089
  • [Presentation] Subtle effect of HLA classI-driven selective forces on thevariability of HIV-1 accessory genes2011

    • Author(s)
      Zafrul Hasan, J. Carlson, H. Gatanaga,A. Le, C. Brumme, S. Oka, Z. Brumme, T.Ueno
    • Organizer
      12th Kumamoto AIDS Seminar and GCOEJoint International Symposium
    • Place of Presentation
      HotelNikko Kumamoto and Aso ResortGrandvrio Hotel, Kumamoto, Japan
    • Data Source
      KAKENHI-PROJECT-22390089
  • [Presentation] Nef のウイルスレセプター発現低下機能と病態2011

    • Author(s)
      緒方陽子、大津家裕仁、Philip Mwimanzi、徳永美知代、Tristan Markle、三浦聡之、Bruce Walker 、Zabrina Brumme 、MarkBrockman、上野貴将
    • Organizer
      一般演題「アクセサリー遺伝子-2」 第25回日本エイズ学会学術集会・総会
    • Place of Presentation
      ハイアットリージェンシー東京
    • Data Source
      KAKENHI-PROJECT-23659232
  • [Presentation] Impact of HLA class I-drivengenetic variability in HIV-1 accessorygenes2011

    • Author(s)
      Zafrul Hasan, J. Carlson, H. Gatanaga,A. Le, C. Brumme, S. Oka, Z. Brumme, T.Ueno
    • Organizer
      2011 The Annual Meeting of theJapanese Society for Immunology
    • Place of Presentation
      Chiba,Makuhari Messe, Japan
    • Data Source
      KAKENHI-PROJECT-23659232
  • [Presentation] Subtle effect of HLA classI-driven selective forces on thevariability of HIV-1 accessory genes2011

    • Author(s)
      Zafrul Hasan, J. Carlson, H. Gatanaga,A. Le, C. Brumme, S. Oka, Z. Brumme, T.Ueno
    • Organizer
      12th Kumamoto AIDS Seminar and GCOEJoint International Symposium
    • Place of Presentation
      HotelNikko Kumamoto and Aso ResortGrandvrio Hotel, Kumamoto, Japan
    • Data Source
      KAKENHI-PROJECT-23659232
  • [Presentation] Effect of HLA class I-mediatedselective pressure on HIV-1 accessorygenes2011

    • Author(s)
      Zafrul Hasan, J. Carlson, H. Gatanaga,A. Le, C. Brumme, S. Oka, Z. Brumme, T.Ueno
    • Organizer
      International Union ofMicrobiological Societies 2011Congress: Virus and host response
    • Place of Presentation
      Sapporo Convention Center, Sapporo,Japan
    • Data Source
      KAKENHI-PROJECT-23659232
  • [Presentation] Population analysis ofviral replication capacity by nefalleles of HIV elite controllers2011

    • Author(s)
      Philip Mwimanzi, Tristan Markle,Michiyo Tokunaga, Toshiyuki Miura,Eric Martin, Florencia Pereyra, BruceWalker, Zabrina Brumme, Mark Brockman,Takamasa Ueno
    • Organizer
      12thKumamoto AIDS Seminar
    • Place of Presentation
      Kumamoto, Japan
    • Data Source
      KAKENHI-PROJECT-22390089
  • [Presentation] Implication of the effects of hostimmune responses on the HIV-1 vpu geneevolution2010

    • Author(s)
      Zafrul Hasan, Hiroyuki Gatanaga,Shinichi Oka, and Takamasa Ueno
    • Organizer
      24th Annual Meeting of theJapanese Society for AIDS Research
    • Place of Presentation
      Grand Prince Hotel Takanawa, PrinceSakura Tower, Takanawa, Tokyo
    • Data Source
      KAKENHI-PROJECT-22390089
  • [Presentation] Implication of the effects of hostimmune responses on the HIV-1 vpu geneevolution2010

    • Author(s)
      Zafrul Hasan, Hiroyuki Gatanaga,Shinichi Oka, and Takamasa Ueno
    • Organizer
      The 11th KUMAMOTO AIDSSeminar and GCOE Joint InternationalSymposium
    • Place of Presentation
      Hotel Nikko Kumamoto andAso Resort Grandvrio Hotel, Kumamoto,Japan
    • Data Source
      KAKENHI-PROJECT-22390089
  • [Presentation] Nef activity in downregulation of viral receptors andprotection of HIV superinfection ismodulated by Nef mutations that conferCTL escape during acute infection2010

    • Author(s)
      Mwimanzi, P., Oniangue-Ndza, C., AllenT.M., and Ueno,T
    • Organizer
      11th KUMAMOTO AIDS Seminar GCOE JointInternational Symposium
    • Place of Presentation
      Hotel NikkoKumamoto and Aso Grand Vrio Hotel,Kumamoto, Japan
    • Data Source
      KAKENHI-PROJECT-22390089
  • [Presentation] CTL-escape Nefvariants influence CCR5 downregulation and HIV superinfectionsusceptibility2010

    • Author(s)
      Mwimanzi P., Ueno T
    • Organizer
      The 14thInternational Conference ofImmunology (ICI)
    • Place of Presentation
      Kobe InternationalExhibition and Portopia Hotel, Kobe,Japan
    • Data Source
      KAKENHI-PROJECT-22390089
  • [Presentation] The effects of CTL-escape conferring mutations on Nef's pathogenic functions in primary macrophages2009

    • Author(s)
      Philip Mwimanzi, M. Fujiwara, M. Takiguchi, Takamasa Ueno
    • Organizer
      Keystone Symposium -HIV immunobiology : From Infection to Immune Control, Keystone Resort, Keystone
    • Place of Presentation
      Colorado, USA
    • Data Source
      KAKENHI-PROJECT-19590479
  • [Presentation] Antiviral activity of HIV-specific cytotoxic T lymphocytes is influenced by intrinsic cooperative thermodynamics of peptide-MHC complexes2009

    • Author(s)
      C. Motozono, S. Yanaka, K. Tsumoto, M. Takiguchi, Takamasa Ueno
    • Organizer
      Keystone Syposium -HIV immunobiology : From Infection to Immune Control, Keystone Resort, Keystone
    • Place of Presentation
      Colorado, USA
    • Data Source
      KAKENHI-PROJECT-19590479
  • [Presentation] CTL-mediated selective pressure and pathogenic functions of Nef2009

    • Author(s)
      Ueno, T.
    • Organizer
      Meeting on HIV research in Mexico
    • Place of Presentation
      Mexico City, Mexico
    • Year and Date
      2009-10-09
    • Data Source
      KAKENHI-PROJECT-21659115
  • [Presentation] HIV特異的T細胞の抗原特異性と抗原変異に対する交差反応性、一般口演「レンチウイルス、HIV(7)」2008

    • Author(s)
      本園千尋、滝口雅文、上野貴将
    • Organizer
      第56回日本ウイルス学会学術集会
    • Place of Presentation
      岡山コンベンションセンター
    • Data Source
      KAKENHI-PROJECT-19590479
  • [Presentation] 抗原ペプチド・MHC複合体の安定性はT細胞の抗ウイルス機能に影響する、ワークショップ「ウイルス感染-2」2008

    • Author(s)
      本園千尋、滝口雅文、上野貴将
    • Organizer
      第38回日本免疫学会学術集会
    • Place of Presentation
      国立京都国際会館
    • Data Source
      KAKENHI-PROJECT-19590479
  • [Presentation] The effects of CTL-escape conferring mutations on Nef's pathogenic functions in primary macrophages、一般口演「O-35)アクセサリー」2008

    • Author(s)
      Mwimanzi Philip、藤原守、滝口雅文、上野貴将
    • Organizer
      第22回日本エイズ学会学術集会・総会
    • Place of Presentation
      大阪国際交流センター
    • Data Source
      KAKENHI-PROJECT-19590479
  • [Presentation] ヒト免疫監視システムとHIVの適応馴化シンポジウム「ヒトはなぜエイズになるのか」2008

    • Author(s)
      上野貴将
    • Organizer
      第22回日本エイズ学会学術集会
    • Place of Presentation
      大阪国際交流センター
    • Data Source
      KAKENHI-PROJECT-19590479
  • [Presentation] The balance of power : Nef and CTL2008

    • Author(s)
      Takamasa Ueno
    • Organizer
      9th AIDS Seminar in KUMAMOTO
    • Place of Presentation
      Kumamoto, Japan
    • Data Source
      KAKENHI-PROJECT-19590479
  • [Presentation] The effects of CTL-escape conferring mutations on Nef's pathogenic functions in primary macrophages2008

    • Author(s)
      Philip Mwimanzi, Mamoru Fujiwara, Masafumi Takiguchi, Takamasa Ueno
    • Organizer
      9th AIDS Seminar in KUMAMOTO
    • Place of Presentation
      Kumamoto, Japan
    • Data Source
      KAKENHI-PROJECT-19590479
  • [Presentation] The effect of TCR-peptide-MHC interactions on antiviral activity and cross-reactive capacity of HIV-specific CTLs2008

    • Author(s)
      Chihiro Motozono, Masafumi Takiguchi, and Takamasa Ueno
    • Organizer
      Keystone Symposia -HIV Pathogenesis-
    • Place of Presentation
      Banff, Canada
    • Data Source
      KAKENHI-PROJECT-19590479
  • [Presentation] CTL-mediated selective pressure influences dynamic evolution and pathogenic functions of HIV-1 Nef2008

    • Author(s)
      Takamasa Ueno, Chihiro Motozono, Sachi Douki, Susanne Rauch, Philip Mwimanzi, Oliver T. Fackler, Shinichi Oka, Masafumi Takiguchi
    • Organizer
      XVII International AIDS Conference
    • Place of Presentation
      Mexico City
    • Data Source
      KAKENHI-PROJECT-19590479
  • [Presentation] 抗原ペプチド複合体の内在的安定性はCTLの抗ウイルス活性に影響する、一般口演「O-37)免疫」2008

    • Author(s)
      本園千尋、滝口雅文、上野貴将
    • Organizer
      第22回日本エイズ学会学術集会・総会
    • Place of Presentation
      大阪国際交流センター
    • Data Source
      KAKENHI-PROJECT-19590479
  • [Presentation] The decay of peptide-MHC complex influences antiviral activity of HIV-specific CTLs2008

    • Author(s)
      Chihiro Motozono, Masafumi Takiguchi, Takamasa Ueno
    • Organizer
      9th AIDS Seminar in KUMAMOTO
    • Place of Presentation
      Kumamoto, Japan
    • Data Source
      KAKENHI-PROJECT-19590479
  • [Presentation] CTL-mediated selective pressure influences dynamic evolution and pathogenic functions of HIV-1 Nef2007

    • Author(s)
      Takamasa Ueno, Chihiro Motozono, Sachi Douki, Susanne Rauch, Philip Mwimanzi, Oliver T. Fackler, Shinichi Oka, Masafumi Takiguchi
    • Organizer
      AIDS Vaccine 07
    • Place of Presentation
      Seattle, USA
    • Data Source
      KAKENHI-PROJECT-19590479
  • [Presentation] CTL-mediated selective pressure modulates pathogenic functions of HIV-1 Nef2007

    • Author(s)
      Takamasa Ueno, Chihiro Motozono, Sachi Douki, Shinichi Oka, Masafumi Takiguchi
    • Organizer
      Keystone Symposia-Molecular and Cellular Determinants of HIV Pathogenesis-
    • Place of Presentation
      Whistler, Canada
    • Data Source
      KAKENHI-PROJECT-19590479
  • [Presentation] The impact of CTL-mediated selective forces on pathogenic functions of HIV-1 Nef2007

    • Author(s)
      Takamasa Ueno
    • Organizer
      Center for AIDS Research, Kumamoto University, 10th Anniversary Symposium
    • Place of Presentation
      Kumamoto, Japan
    • Data Source
      KAKENHI-PROJECT-19590479
  • [Presentation] CTL-mediated selective pressure influences dynamic evolution and pathogenic functions of HIV-1 Nef2007

    • Author(s)
      Takamasa Ueno, Chihiro Motozono, Sachi Douki, Susanne Rauch, Philip Mwimanzi, Oliver T. Fackler, Shinichi Oka, Masafumi Takiguchi
    • Organizer
      8th AIDS Seminar in KUMAMOTO
    • Place of Presentation
      Kumamoto, Japan
    • Data Source
      KAKENHI-PROJECT-19590479
  • [Presentation] Ability of HIV-1-specific CTL to suppress HIV-1 replication and selection of escape mutants in chronically HIV-1-infected individuals2007

    • Author(s)
      Koizumi, H., Iwatani, T., Hachiya, A., Kawashima, Y., Ueno, T., Oka, S., and Takiguchi, M.
    • Organizer
      8th AIDS Seminar in KUMAMOTO
    • Place of Presentation
      Kumamoto, Japan
    • Data Source
      KAKENHI-PROJECT-19590479
  • [Presentation] CTL-mediated selective pressure influences dynamic evolution and pathogenic functions of HIV-1 Nef2007

    • Author(s)
      上野貴将、本園千尋、道木佐知、Philip Mwimanzi、岡慎一、滝口雅文
    • Organizer
      ワークショップ第37回日本免疫学会総会・学術集会
    • Place of Presentation
      高輪プリンスホテル
    • Year and Date
      2007-11-20
    • Data Source
      KAKENHI-PROJECT-19590479
  • [Presentation] HIV Nefの病原性機能維持と宿主免疫淘汰圧ワークショップ2007

    • Author(s)
      上野貴将、本園千尋、道木佐知、岡慎一、滝口雅文
    • Organizer
      第55回日本ウイルス学会学術集会
    • Place of Presentation
      札幌コンベンションセンター
    • Data Source
      KAKENHI-PROJECT-19590479
  • [Presentation] HIV Nefの病原性機能維持と宿主免疫淘汰圧2007

    • Author(s)
      上野 貴将
    • Organizer
      第55回日本ウイルス学会学術集会
    • Place of Presentation
      札幌コンベンションセンター
    • Data Source
      KAKENHI-PROJECT-19590479
  • [Presentation] CTL-mediated selective pressure influences dynamic evolution and pathogenic functions of HIV-1 Nef2007

    • Author(s)
      T.Ueno
    • Organizer
      AIDS Vaccine Conference
    • Place of Presentation
      Seattle,WA.U.S.A.
    • Data Source
      KAKENHI-PROJECT-19590479
  • [Presentation] The capacity of antigenic peptides that dictates antiviral activity of Cytotoxic T Lymphocytes2007

    • Author(s)
      Chihiro Motozono, Masafumi Takiguchi, Takamasa Ueno
    • Organizer
      8th AIDS Seminar in KUMAMOTO
    • Place of Presentation
      Kumamoto, Japan
    • Data Source
      KAKENHI-PROJECT-19590479
  • [Presentation] Differential down-regulation of the HLA class I allotypes by HIV-1 Nef primary isolate.

    • Author(s)
      Mahiti M, Jia X, Toyoda M, Mwimanzi F, Walker BD, Brumme ZL, Brockman MA, Xiong Y, Ueno T.
    • Organizer
      The annual Conference on Retroviruses and Opportunistic Infections (CROI).
    • Place of Presentation
      シアトル・アメリカ
    • Year and Date
      2015-02-23 – 2015-02-26
    • Data Source
      KAKENHI-PROJECT-24390254
  • [Presentation] Dynamic range of down-regulation of HIV-1 entry receptors by primary Nef isolates.

    • Author(s)
      Toyoda M, Ogata Y, Mahiti M, Pereyra F, Miura T, Walker BD, Brumme ZL, Brockman MA, Ueno T.
    • Organizer
      The annual Conference on Retroviruses and Opportunistic Infections (CROI).
    • Place of Presentation
      シアトル・アメリカ
    • Year and Date
      2015-02-23 – 2015-02-26
    • Data Source
      KAKENHI-PROJECT-24390254
  • [Presentation] Effects of natural variability of Vpr on immunological footprints and protein functions.

    • Author(s)
      Kamori D, Murakami T, Hasan Z, Meribe S, Carlson J, Siarot L, Miura T, Kawana-Tachikawa A, Iwamoto A, Gatanaga H, Oka S, Aida Y, Ueno T.
    • Organizer
      Keystone Symposia HIV Vaccines (X5)
    • Place of Presentation
      バンフ・カナダ
    • Year and Date
      2015-03-22 – 2015-03-27
    • Data Source
      KAKENHI-PROJECT-24390254
  • [Presentation] Impact of HLA class I-driven genetic variability in HIV-1 accessory gene vpu.

    • Author(s)
      Zafrul Hasan, J. Carlson, H. Gatanaga, A. Le, S. Oka, Z. Brumme, Takamasa Ueno.
    • Organizer
      COLD SPRING HARBOR ASIA CONFERENCES: Frontiers of Immunology in Health and Disease.
    • Place of Presentation
      中国蘇州
    • Data Source
      KAKENHI-PROJECT-24390254
  • 1.  TAKIGUCHI Masafumi (00183450)
    # of Collaborated Projects : 4results
    # of Collaborated Products : 1results
  • 2.  MIURA Toshiyuki (00296576)
    # of Collaborated Projects : 1results
    # of Collaborated Products : 7results
  • 3.  GATANAGA Hiroyuki (10466211)
    # of Collaborated Projects : 1results
    # of Collaborated Products : 11results
  • 4.  KODAMA Eiichi (50271151)
    # of Collaborated Projects : 1results
    # of Collaborated Products : 0results
  • 5.  冨山 宏子 (50301370)
    # of Collaborated Projects : 1results
    # of Collaborated Products : 0results
  • 6.  佐藤 賢文 (70402807)
    # of Collaborated Projects : 1results
    # of Collaborated Products : 0results
  • 7.  勝屋 弘雄 (80632041)
    # of Collaborated Projects : 1results
    # of Collaborated Products : 0results
  • 8.  津本 浩平
    # of Collaborated Projects : 0results
    # of Collaborated Products : 1results

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