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Itoh Ken  伊東 健

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ITOH Ken  伊東 健

伊東 健  イトウ ケン

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Researcher Number 10323289
Other IDs
Affiliation (Current) 2025: 弘前大学, 医学研究科, 教授
Affiliation (based on the past Project Information) *help 2021 – 2024: 弘前大学, 医学研究科, 教授
2016 – 2018: 弘前大学, 医学研究科, 教授
2012 – 2016: 弘前大学, 医学(系)研究科(研究院), 教授
2012: 弘前大学, 医学研究科, 教授
2007 – 2011: Hirosaki University, Hirosaki University, Graduate School of Medicine, Professor
2006: 弘前大学, 医学部, 教授
2001 – 2003: 筑波大学, 基礎医学系, 講師
Review Section/Research Field
Principal Investigator
General medical chemistry / Biological Sciences / Pathological medical chemistry / Biological Sciences / General medical chemistry
Except Principal Investigator
Basic Section 59040:Nutrition science and health science-related / Basic Section 56050:Otorhinolaryngology-related / Transformative Research Areas, Section (III) / Risk sciences of radiation/Chemicals / Biological Sciences
Keywords
Principal Investigator
Nrf2 / 酸化ストレス / GCN1L1 / ATF4 / マクロファージ / ミトコンドリア / HO-1 / GCN1 / アミノ酸飢餓 / 動脈硬化症 … More / 転写因子 / GCN2 / ストレス応答 / 活性酸素 / 転写複合体 / Z-DNA / Keap1 / endothelial cell / macrophage / atherosclerosis / 血管内皮細胞 / ヘムオキシゲナーゼ1 / プロテオスタシス / eIF2alpha / 酸素ストレス / プロテアソーム / リボソーム / Z-DRA / ApoEノックアウトマウス / ferroportin1 / 鉄トランスポーター / 転写共役因子 / 酸化ストレス応答 / アミノ酸化飢餓応答 / 転写制御 / クロマチンリモデリング因子 / 遺伝子発現制御 / グルタチオントランスフェラーゼ / グロタチオントランスフェラーゼ / Neh2 / 解毒化酵素 … More
Except Principal Investigator
A549 / CD36 / Nrf2 / A170 / HO-1 / Fe-NTA / Prx I / 酸化ストレス / スペルミジンオキシだーぜ / Nrf1 / 不良タンパク質蓄積 / リボソーム衝突 / ポリアミン / リポソームコリジョン / アクロレイン / 老化 / 遺伝子検査 / 疫学調査 / 遺伝子解析 / 疫学的調査 / 一般地域住民 / ミトコンドリア機能 / 加齢性難聴 / 転写制御 / エネルギー産生 / 硫黄代謝 / 炎症応答 / 慢性低酸素 / 超硫黄分子 / 低酸素 / ミトコンドリア / 超硫黄 / phenanthraquinone / パーオキシレドキシン / Cu,Zn-SOD / キノン / ヒ素 / HSP70 / スルフォラファン / ニトロキシルラジカル / フェナントラキノン / 生体分子 / 生理活性 / ケミカルバイオロジー / シグナル伝達 / 活性酸素 Less
  • Research Projects

    (12 results)
  • Research Products

    (158 results)
  • Co-Researchers

    (37 People)
  •  一般地域住民に対する大規模疫学調査による加齢性難聴の遺伝的素因の解明

    • Principal Investigator
      佐々木 亮
    • Project Period (FY)
      2022 – 2024
    • Research Category
      Grant-in-Aid for Scientific Research (C)
    • Review Section
      Basic Section 56050:Otorhinolaryngology-related
    • Research Institution
      Hirosaki University
  •  Controlling the anti aging mechanism through modification of the protein translation pathway and Amine metabolizing pathway

    • Principal Investigator
      辻田 忠志
    • Project Period (FY)
      2022 – 2024
    • Research Category
      Grant-in-Aid for Scientific Research (B)
    • Review Section
      Basic Section 59040:Nutrition science and health science-related
    • Research Institution
      Saga University
  •  Mitochondrial supersulfides for energy production and hypoxia adaptation

    • Principal Investigator
      本橋 ほづみ
    • Project Period (FY)
      2021 – 2025
    • Research Category
      Grant-in-Aid for Transformative Research Areas (A)
    • Review Section
      Transformative Research Areas, Section (III)
    • Research Institution
      Tohoku University
  •  Elucidation of redox regulatory mechanisms by transcription factor networkPrincipal Investigator

    • Principal Investigator
      Itoh Ken
    • Project Period (FY)
      2014 – 2018
    • Research Category
      Grant-in-Aid for Scientific Research on Innovative Areas (Research in a proposed research area)
    • Review Section
      Biological Sciences
    • Research Institution
      Hirosaki University
  •  Analysis of novel oxidative stress response mechanism via ribosomePrincipal Investigator

    • Principal Investigator
      Itoh Ken
    • Project Period (FY)
      2013 – 2017
    • Research Category
      Grant-in-Aid for Scientific Research (B)
    • Research Field
      General medical chemistry
    • Research Institution
      Hirosaki University
  •  Nrf2 activation mechanism mediated by amino acid starvation response factor GCN1L1Principal Investigator

    • Principal Investigator
      ITOH Ken
    • Project Period (FY)
      2012
    • Research Category
      Grant-in-Aid for Challenging Exploratory Research
    • Research Field
      General medical chemistry
    • Research Institution
      Hirosaki University
  •  Nrf2を介した転写制御機構の分子基盤の解析Principal Investigator

    • Principal Investigator
      伊東 健
    • Project Period (FY)
      2008
    • Research Category
      Grant-in-Aid for Scientific Research on Priority Areas
    • Review Section
      Biological Sciences
    • Research Institution
      Hirosaki University
  •  Signaling Functions of Reactive Oxygen Species

    • Principal Investigator
      AKAIKE Takaaki
    • Project Period (FY)
      2008 – 2013
    • Research Category
      Grant-in-Aid for Scientific Research on Innovative Areas (Research in a proposed research area)
    • Review Section
      Biological Sciences
    • Research Institution
      Tohoku University
      Kumamoto University
  •  Transcriptional regulation by reactive oxygen speciesPrincipal Investigator

    • Principal Investigator
      ITOH Ken
    • Project Period (FY)
      2008 – 2012
    • Research Category
      Grant-in-Aid for Scientific Research on Innovative Areas (Research in a proposed research area)
    • Review Section
      Biological Sciences
    • Research Institution
      Hirosaki University
  •  The role of transcription factor Nrf2 for atherosclerosisPrincipal Investigator

    • Principal Investigator
      ITOH Ken
    • Project Period (FY)
      2006 – 2007
    • Research Category
      Grant-in-Aid for Scientific Research (C)
    • Research Field
      Pathological medical chemistry
    • Research Institution
      Hirosaki University
  •  New evaluation system of cell damage caused by environmental chemicals that effect lifestyle diseases

    • Principal Investigator
      ISHII Tetsuro
    • Project Period (FY)
      2003 – 2005
    • Research Category
      Grant-in-Aid for Scientific Research (B)
    • Research Field
      Risk sciences of radiation/Chemicals
    • Research Institution
      University of Tsukuba
  •  酸化ストレスによる転写因子Nrf2の活性化機構の解析Principal Investigator

    • Principal Investigator
      伊東 健
    • Project Period (FY)
      2001 – 2002
    • Research Category
      Grant-in-Aid for Young Scientists (B)
    • Research Field
      General medical chemistry
    • Research Institution
      University of Tsukuba

All 2024 2023 2022 2019 2018 2017 2016 2015 2014 2013 2012 2011 2010 2009 2008 2004 Other

All Journal Article Presentation Book

  • [Book] 2.ATFとNrf2によるミトコンドリアホメオスタシスレドックス制御2018

    • Author(s)
      葛西秋宅、對馬迪子、伊東健
    • Total Pages
      5
    • Publisher
      羊土社
    • Data Source
      KAKENHI-PROJECT-25293064
  • [Book] ATF4とNrf2によるミトコンドリアホメオスタシス制御2018

    • Author(s)
      葛西秋宅、對馬迪子、伊東健
    • Total Pages
      5
    • Publisher
      羊土社
    • Data Source
      KAKENHI-PLANNED-26111010
  • [Book] Fukushima Nuclear Accident: Global Implications, Long-Term Health Effects, and Ecological Consequences.2015

    • Author(s)
      Itoh K, Maruyama A.
    • Total Pages
      18
    • Publisher
      Nova
    • Data Source
      KAKENHI-PROJECT-25293064
  • [Journal Article] Emerging Role of GCN1 in Disease and Homeostasis2024

    • Author(s)
      Yota Tatara, Shuya Kasai, Daichi Kokubu, Tadayuki Tsujita, Junsei Mimura, and Ken Itoh
    • Journal Title

      International Journal of Molecular Sciences

      Volume: 25 Issue: 5 Pages: 2998-2998

    • DOI

      10.3390/ijms25052998

    • Peer Reviewed / Open Access / Int'l Joint Research
    • Data Source
      KAKENHI-PROJECT-22K06891, KAKENHI-PROJECT-23K24772
  • [Journal Article] Association of mitochondrial DNA haplogroup and hearing impairment with aging in Japanese general population of the Iwaki Health Promotion Project2022

    • Author(s)
      Miura Shiori、Sasaki Akira、Kasai Shuya、Sugawara Takayuki、Maeda Yasunori、Goto Shinichi、Kasai Takashi、Shimizume Nami、Jung Songee、Iwane Takuro、Itoh Ken、Matsubara Atsushi
    • Journal Title

      Journal of Human Genetics

      Volume: なし Issue: 6 Pages: 369-375

    • DOI

      10.1038/s10038-022-01011-6

    • Peer Reviewed / Open Access
    • Data Source
      KAKENHI-PROJECT-19K18756, KAKENHI-PROJECT-22K09719
  • [Journal Article] Concomitant Nrf2- and ATF4-activation by Carnosic Acid Cooperatively Induces Expression of Cytoprotective Genes.2019

    • Author(s)
      Mimura J, Inose-Maruyama A, Taniuchi S, Kosaka K, Yoshida H, Yamazaki H, Kasai S, Harada N, Kaufman RJ, Oyadomari S, Itoh K.
    • Journal Title

      International Journal of Molecular Sciences

      Volume: 20 Issue: 7 Pages: 1706-1706

    • DOI

      10.3390/ijms20071706

    • NAID

      120006939608

    • Peer Reviewed / Open Access / Int'l Joint Research
    • Data Source
      KAKENHI-PROJECT-17K08616, KAKENHI-PLANNED-26111010
  • [Journal Article] Role of the ISR-ATF4 pathway and its cross talk with Nrf2 in mitochondrial quality control2019

    • Author(s)
      Kasai S, Yamazaki H, Tanji K, Engler MJ, Matsumiya T, Itoh K.
    • Journal Title

      Journal of Clinical Biochemistry and Nutrition

      Volume: 64 Issue: 1 Pages: 1-12

    • DOI

      10.3164/jcbn.18-37

    • NAID

      130007542293

    • ISSN
      0912-0009, 1880-5086
    • Language
      English
    • Peer Reviewed / Open Access
    • Data Source
      KAKENHI-PROJECT-17K08616, KAKENHI-PROJECT-17K10012, KAKENHI-PLANNED-26111010, KAKENHI-PROJECT-17K07089
  • [Journal Article] Emerging regulatory role of Nrf2 in iron, heme and hemoglobin metabolism in physiology and disease.2018

    • Author(s)
      Kasai S, Mimura J, Ozaki T, Itoh K.
    • Journal Title

      Front. Vet Sci

      Volume: 5 Pages: 242-242

    • DOI

      10.3389/fvets.2018.00242

    • Peer Reviewed / Open Access
    • Data Source
      KAKENHI-PLANNED-26111010
  • [Journal Article] C151 in KEAP1 is the main cysteine sensor for the cyanoenone class of NRF2 activators, irrespective of molecular size or shape2018

    • Author(s)
      Dayalan Naidu Sharadha、Muramatsu Aki、Saito Ryota、Asami Soichiro、Honda Tadashi、Hosoya Tomonori、Itoh Ken、Yamamoto Masayuki、Suzuki Takafumi、Dinkova-Kostova Albena T.
    • Journal Title

      Scientific Reports

      Volume: 8 Issue: 1 Pages: 8037-8037

    • DOI

      10.1038/s41598-018-26269-9

    • Peer Reviewed / Open Access / Int'l Joint Research
    • Data Source
      KAKENHI-PROJECT-18K19417, KAKENHI-PROJECT-17KK0183, KAKENHI-PUBLICLY-18H04963, KAKENHI-PLANNED-26111002, KAKENHI-PLANNED-26111010, KAKENHI-PROJECT-17K15590
  • [Journal Article] Increase in proapoptotic activity of inhibitory PAS domain protein via phosphorylation by MK22017

    • Author(s)
      Kasai Shuya、Richardson Mary J. E.、Torii Satoru、Yasumoto Ken-ichi、Shima Hiroki、Igarashi Kazuhiko、Itoh Ken、Sogawa Kazuhiro、Murayama Kazutaka
    • Journal Title

      The FEBS Journal

      Volume: 284 Issue: 23 Pages: 4115-4127

    • DOI

      10.1111/febs.14300

    • Peer Reviewed / Int'l Joint Research
    • Data Source
      KAKENHI-PLANNED-26111010, KAKENHI-PROJECT-25293064
  • [Journal Article] Effects of deficiency of Kelch-like ECH-associated protein 1 on skeletal organization: a mechanism for diminished nuclear factor of activated T cells cytoplasmic-1 during osteoclastogenesis2017

    • Author(s)
      Sakai E., Morita M., Ohuchi M., Kido MA., Fukuma Y., Nishishita K., Okamoto K., Itoh K., Yamamoto M, and Tsukuba T
    • Journal Title

      FASEB Journal

      Volume: 31 Issue: 9 Pages: 4011-4022

    • DOI

      10.1096/fj.201700177r

    • Peer Reviewed / Open Access
    • Data Source
      KAKENHI-PROJECT-16K11480, KAKENHI-PLANNED-26111002, KAKENHI-PLANNED-26111010, KAKENHI-PROJECT-15H05298, KAKENHI-PROJECT-17H04379, KAKENHI-PROJECT-16K11510, KAKENHI-PROJECT-16K15790, KAKENHI-PROJECT-25293064
  • [Journal Article] Novel roles of glycosaminoglycans in the degradation of type I collagen by cathepsin K2017

    • Author(s)
      Tatara Yota, Suto Shintaro, Itoh Ken
    • Journal Title

      Glycobiology

      Volume: 284 Issue: 12 Pages: 1089-1098

    • DOI

      10.1093/glycob/cwx083

    • Peer Reviewed
    • Data Source
      KAKENHI-PLANNED-26111010, KAKENHI-PROJECT-25293064
  • [Journal Article] The BET bromodomain inhibitor exerts the most potent synergistic anticancer effects in combination with quinone-containing compounds and anti-microtubule drugs2016

    • Author(s)
      2.Liu PY, Sokolowski N, Guo ST, Siddiqi F, Atmadibrata B, Telfer TJ, Sun Y, Zhang L, Yu D, Mccarroll J, Liu B, Yang RH, Guo XY, Tee AE, Itoh K, Wang J, Kavallaris M, Haber M, Norris MD, Cheung BB, Byrne JA, Ziegler DS, Marshall GM, Dinger ME, Codd R, Zhang XD, Liu T
    • Journal Title

      Oncotarget

      Volume: 7 Issue: 48 Pages: 79217-79232

    • DOI

      10.18632/oncotarget.12640

    • Peer Reviewed / Open Access / Int'l Joint Research
    • Data Source
      KAKENHI-PLANNED-26111010, KAKENHI-PROJECT-25293064
  • [Journal Article] p62 Deficiency Enhances α-Synuclein Pathology in Mice.2015

    • Author(s)
      Tanji K, Odagiri S, Miki Y, Maruyama A, Nikaido Y, Mimura J, Mori F, Warabi E, Yanagawa T, Ueno S, Itoh K, Wakabayashi K.
    • Journal Title

      Brain Pathol.

      Volume: 印刷中 Issue: 5 Pages: 552-564

    • DOI

      10.1111/bpa.12214

    • Peer Reviewed / Open Access
    • Data Source
      KAKENHI-PROJECT-25220103, KAKENHI-PROJECT-25860202, KAKENHI-PROJECT-26430049, KAKENHI-PLANNED-26111010, KAKENHI-PROJECT-24300131
  • [Journal Article] Role of Nrf2 in the pathogenesis of atherosclerosis.2015

    • Author(s)
      Mimura J, Itoh K
    • Journal Title

      Free Radic Biol Med.

      Volume: 88 Pages: 221-232

    • DOI

      10.1016/j.freeradbiomed.2015.06.019

    • Peer Reviewed / Acknowledgement Compliant
    • Data Source
      KAKENHI-PLANNED-26111010, KAKENHI-PROJECT-25293064
  • [Journal Article] Role of the Keap1/Nrf2 pathway in neurodegenerative diseases.2015

    • Author(s)
      Yamazaki H, Tanji K, Wakabayashi K, Matsuura S, Itoh K.
    • Journal Title

      Pathol Int

      Volume: 65 Issue: 5 Pages: 210-9

    • DOI

      10.1111/pin.12261

    • Peer Reviewed / Acknowledgement Compliant
    • Data Source
      KAKENHI-PROJECT-26860178, KAKENHI-PLANNED-26111010, KAKENHI-PROJECT-25293064
  • [Journal Article] Phosphorylation of serine 349 of p62 in Alzheimer’s disease brain.2014

    • Author(s)
      Tanji K, Miki Y, Ozaki T, Maruyama A, Yoshida H, Mimura J, Matsumiya T, Mori F, Imaizumi T, Itoh K, Kakita A, Takahashi H, Wakabayashi K.
    • Journal Title

      Acta Neuropathologica Communications

      Volume: 未定

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-25293064
  • [Journal Article] Nrf2- and ATF4-dependent up-regulation of xCT modulates the sensitivity of T24 bladder carcinoma cells to proteasome inhibition.2014

    • Author(s)
      Peng Ye, P., Mimura J., Okada, T., Sato, H., Liu, T., Maruyama, A., Ohyama, C., and Itoh, K.
    • Journal Title

      Mol. Cell. Biol.

      Volume: 34 Issue: 18 Pages: 3421-3434

    • DOI

      10.1128/mcb.00221-14

    • Peer Reviewed / Open Access
    • Data Source
      KAKENHI-PROJECT-24500967, KAKENHI-PROJECT-25293064, KAKENHI-PROJECT-25860202, KAKENHI-PLANNED-26111010
  • [Journal Article] Non-coding RNA derived from the region adjacent to the human HO-1 E2 enhancer selectively regulates HO-1 gene induction by modulating Pol II binding.2014

    • Author(s)
      Maruyama A, Mimura J, Itoh K.
    • Journal Title

      Nucleic Acids Res

      Volume: 42 Issue: 22 Pages: 13599-13614

    • DOI

      10.1093/nar/gku1169

    • Peer Reviewed / Open Access
    • Data Source
      KAKENHI-PROJECT-25293064, KAKENHI-PROJECT-25860202, KAKENHI-ORGANIZER-26111001, KAKENHI-PLANNED-26111010
  • [Journal Article] Nrf2 activation is associated with Z-DNA formation in the human HO-1 promoter2013

    • Author(s)
      Maruyama A, Mimura J, Harada N, Itoh K
    • Journal Title

      Nucleic Acids Res

      Volume: (in press) Issue: 10 Pages: 12-12

    • DOI

      10.1093/nar/gkt243

    • Peer Reviewed
    • Data Source
      KAKENHI-PLANNED-20117010, KAKENHI-PROJECT-23790319, KAKENHI-PROJECT-24659122, KAKENHI-PROJECT-24790305, KAKENHI-PROJECT-25293064, KAKENHI-PROJECT-25860202
  • [Journal Article] Carnosic acid suppresses the production of amyloid-β 1-42 by inducing the metalloprotease gene TACE/ADAM17 in SH-SY5Y human neuroblastoma cells2013

    • Author(s)
      Meng P, Yoshida H, Matsumiya T, Imaizumi T, Tanji K, Xing F, Hayakari R, Dempoya J, Tatsuta T, Aizawa-Yashiro T, Mimura J, Kosaka K, Itoh K, Satoh K
    • Journal Title

      Neurosci Res

      Volume: 75 Issue: 2 Pages: 4-102

    • DOI

      10.1016/j.neures.2012.11.007

    • Peer Reviewed
    • Data Source
      KAKENHI-PLANNED-20117010, KAKENHI-PROJECT-23592081, KAKENHI-PROJECT-24659122
  • [Journal Article] Keap1 is localized in neuronal and glial cytoplasmic inclusions in various neurodegenerative diseases2013

    • Author(s)
      Tanji K, Maruyama A, Odagiri S, Mori F, Itoh K, Kakita A, Takahashi H, Wakabayashi K
    • Journal Title

      J Neuropathol Exp Neurol

      Volume: 72 Issue: 1 Pages: 18-28

    • DOI

      10.1097/nen.0b013e31827b5713

    • Peer Reviewed
    • Data Source
      KAKENHI-PLANNED-20117010, KAKENHI-PROJECT-23240049, KAKENHI-PROJECT-23500424, KAKENHI-PROJECT-23500425, KAKENHI-PROJECT-23790319, KAKENHI-PROJECT-24300131, KAKENHI-PROJECT-24659122, KAKENHI-PROJECT-24700363, KAKENHI-PROJECT-25860202
  • [Journal Article] Methylation of the KEAP1 gene promoter region in human colorectal cancer2012

    • Author(s)
      Hanada N, Takahata T, Zhou Q, Ye X, Sun R, Itoh J, Ishiguro A, Kijima H, Mimura J, Itoh K, Fukuda S, Saijo Y
    • Journal Title

      BMC Cancer

      Volume: 12 Issue: 1 Pages: 66-66

    • DOI

      10.1186/1471-2407-12-66

    • Peer Reviewed
    • Data Source
      KAKENHI-PLANNED-20117010, KAKENHI-PROJECT-24659396
  • [Journal Article] Molecular mechanisms for the regulation of Nrf2-mediated cell proliferation in non-small-cell lung cancers2012

    • Author(s)
      Yamadori T, Ishii Y, Homma S, Morishima Y, Kurishima K, Itoh K, Yamamoto M, Minami Y, Noguchi M, Hizawa N
    • Journal Title

      Oncogene

      Volume: 31 Issue: 45 Pages: 4768-4777

    • DOI

      10.1038/onc.2011.628

    • Peer Reviewed
    • Data Source
      KAKENHI-PLANNED-20117010
  • [Journal Article] Nrf2 inhibits hepatic iron accumulation and counteracts oxidative stress-induced liver injury in nutritional steatohepatitis2012

    • Author(s)
      Okada K, Warabi E, Sugimoto H, Horie M, Tokushige K, Ueda T, Harada N, Taguchi K, Hashimoto E, Itoh K, Ishii T, Utsunomiya H, Yamamoto M, Shoda J
    • Journal Title

      J.Gastroenterol

      Volume: (印刷中) Issue: 8 Pages: 924-935

    • DOI

      10.1007/s00535-012-0552-9

    • NAID

      10031051379

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-19GS0312, KAKENHI-PLANNED-20117010, KAKENHI-PROJECT-22300260, KAKENHI-PROJECT-22500656, KAKENHI-PROJECT-22590802, KAKENHI-PROJECT-22790127, KAKENHI-PROJECT-23300250, KAKENHI-PROJECT-23660033, KAKENHI-PROJECT-24650436, KAKENHI-PROJECT-24659104, KAKENHI-PROJECT-24659122, KAKENHI-PROJECT-24790307, KAKENHI-PUBLICLY-23117503
  • [Journal Article] Nrf2 in bone marrow-derived cells positively contributes to the advanced stage of atherosclerotic plaque formation2012

    • Author(s)
      Harada N, Ito K, Hosoya T, Mimura J, Maruyama A, Noguchi N, Yagami KI, Morito N, Takahashi S, Maher JM, Yamamoto M, Itoh K
    • Journal Title

      Free Radic Biol Med

      Volume: 53 Issue: 12 Pages: 2256-2262

    • DOI

      10.1016/j.freeradbiomed.2012.10.001

    • Peer Reviewed
    • Data Source
      KAKENHI-PLANNED-20117010, KAKENHI-PROJECT-23790319, KAKENHI-PROJECT-24249015, KAKENHI-PROJECT-24591223, KAKENHI-PROJECT-24659122, KAKENHI-PROJECT-24790305
  • [Journal Article] The novel NRF2-interacting factor KAP1 regulates the susceptibility to oxidative stress by promoting NRF2-mediated cytoprotective response2011

    • Author(s)
      Maruyama A, Nishikawa K, Kawatani Y, Mimura J, Hosoya T, Harada N, Yamamato M, Itoh K
    • Journal Title

      Biechem J

      Volume: 436 Issue: 2 Pages: 387-397

    • DOI

      10.1042/bj20101748

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-19GS0312, KAKENHI-PLANNED-20117010, KAKENHI-PROJECT-23790319
  • [Journal Article] Edaravone and carnosic acid synergistically enhance the expression of nerve growth factor in human astrocytes under hypoxia/reoxygenation2011

    • Author(s)
      Yoshida H, Mimura J, Imaizumi T, Matsumiya T, Ishikawa A, Metoki N, Tanji K, Ota K, Hayakari R, Kosaka K, Itoh K, Satoh K
    • Journal Title

      Neurosci Res

      Volume: 69 Issue: 4 Pages: 291-298

    • DOI

      10.1016/j.neures.2010.12.016

    • Peer Reviewed
    • Data Source
      KAKENHI-PLANNED-20117010, KAKENHI-PROJECT-23590560, KAKENHI-PROJECT-23592081
  • [Journal Article] Nrf2 regulates NGF mRNA induction by carnosic acid in T98G glioblastoma cells and normal human astrocytes.2011

    • Author(s)
      Mimura J, Kosaka K, Maruyama A, Satoh T, Harada N, Yoshida H, Satoh K, Yamamoto M, Itoh K.Nrf2 regulates NGF mRNA induction by Mimura J, Kosaka K, Maruyama A, Satoh T, Harada N, Yoshida H, Satoh K, Yamamoto M, Itoh K.
    • Journal Title

      J Biochem. in press

    • NAID

      10030587033

    • Peer Reviewed
    • Data Source
      KAKENHI-PLANNED-20117010
  • [Journal Article] Nrf2 regulates ferroportin 1-mediated iron efflux and counteracts lipopolysaccharide-induced ferroportin 1 mRNA suppression in macrophages.2011

    • Author(s)
      Harada N, Kanayama M, Maruyama A, Yoshida A, Tazumi K, Hosoya T, Mimura J, Toki T, Maher JM, Yamamoto M, Itoh K.
    • Journal Title

      Arch Biochem Biophys. 508

      Pages: 101-109

    • Peer Reviewed
    • Data Source
      KAKENHI-PLANNED-20117010
  • [Journal Article] Nrf2 regulates NGF mRNA induction by carnosic acid in T98G glioblastoma cells and normal human astrocytes2011

    • Author(s)
      Mimura J, Kosaka K, Maruyama A, Satoh T, Harada N, Yoshida H, Satoh K, Yamamoto M, Itoh K
    • Journal Title

      J Biochem

      Volume: 150 Issue: 2 Pages: 209-217

    • DOI

      10.1093/jb/mvr065

    • NAID

      10030587033

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-19GS0312, KAKENHI-PLANNED-20117010, KAKENHI-PROJECT-22790304, KAKENHI-PROJECT-23592081, KAKENHI-PROJECT-23790319
  • [Journal Article] The novel Nrf2-interacting factor KAP1 regulates susceptibility to oxidaive stress by promoting the Nrf2-mediated cytoprotective response.2011

    • Author(s)
      Maruyama A, Nishikawa K, Kawatani Y, Mimura J, Hosoya T, Harada N, Yamamato M, Itoh K.
    • Journal Title

      Biochemical J. 436

      Pages: 387-397

    • Peer Reviewed
    • Data Source
      KAKENHI-PLANNED-20117010
  • [Journal Article] Role of Nrf2 in host defense against influenza virus in cigarette smoke-exposed mice2011

    • Author(s)
      Yageta Y, Ishii Y, Morishima Y, Masuko H, Ano S, Yamadori T, Itoh K, Takeuchi K, Yamamoto M, Hizawa N
    • Journal Title

      J Virol

      Volume: 85 Issue: 10 Pages: 4679-4690

    • DOI

      10.1128/jvi.02456-10

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-19GS0312, KAKENHI-PLANNED-20117010
  • [Journal Article] Nrf2 regulates ferroportin 1-mediated iron efflux and counteracts lipopolysaccharide-induced ferroportin-1 mRNA suppression in macrophages2011

    • Author(s)
      Harada N, Kanayama M, Maruyama A, Yoshida A, Tazumi K, Hosoya T, Mimura J, Toki T, Maher JM, Yamamoto M, Itoh K
    • Journal Title

      Arch Biochem Biophys

      Volume: 508 Issue: 1 Pages: 101-109

    • DOI

      10.1016/j.abb.2011.02.001

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-19GS0312, KAKENHI-PLANNED-20117010, KAKENHI-PROJECT-23790319
  • [Journal Article] Syinpilin 1-binding protein NUB1 is colocalized with nonfibrillar, proteinase K-resistant・-synuclein in presynapses in Lewy Body disease2011

    • Author(s)
      Tanji K, Mori F, Kito K, Kakita A, Mimura J, Itoh K, Takahashi H, Kamitani T, Wakabayashi K
    • Journal Title

      J Neuropathol Exp Neurol

      Volume: 70 Issue: 10 Pages: 879-889

    • DOI

      10.1097/nen.0b013e3182303745

    • Peer Reviewed
    • Data Source
      KAKENHI-PLANNED-20117010, KAKENHI-PROJECT-20300123, KAKENHI-PROJECT-23500424, KAKENHI-PROJECT-23500425
  • [Journal Article] Nrf2 degron-fused reporter system ; a new tool for specific evaluation of Nrf2 inducers2011

    • Author(s)
      Hirotsu Y, Katsuoka F, Itoh K, Yamamoto M
    • Journal Title

      Genes Cells

      Volume: 16 Issue: 4 Pages: 406-415

    • DOI

      10.1111/j.1365-2443.2011.01496.x

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-19GS0312, KAKENHI-PLANNED-20117010
  • [Journal Article] p122 protein enhances intracellular calcium increase to acetylcholine: its possible role in the pathogenesis of coronary spastic angina2010

    • Author(s)
      Murakami R, Osanai T, Tomita H, Sasaki S, Maruyama A, Itoh K, Homma Y, Okumura K
    • Journal Title

      Arterioscler Thromb Vasc Biol

      Volume: 30 Issue: 10 Pages: 1968-1975

    • DOI

      10.1161/atvbaha.110.203083

    • Peer Reviewed
    • Data Source
      KAKENHI-PLANNED-20117010
  • [Journal Article] Discovery of the negative regulator of Nrf2, Keap1 : A historical overview.2010

    • Author(s)
      Itoh K, Mimura J, Yamamoto M.
    • Journal Title

      Antioxid Redox Signal. 13

      Pages: 1665-1678

    • Peer Reviewed
    • Data Source
      KAKENHI-PLANNED-20117010
  • [Journal Article] Aggressive mammary carcinoma progression in Nrf2 knockout mice treated with 7,12-dimethylbenz[a]anthracene2010

    • Author(s)
      Becks L, Prince M, Burson H, Christophe C, Broadway M, Itoh K, Yamamoto M, Mathis M, Orchard E, Shi R, McLarty J, Pruitt K, Zhang S, Kleiner-Hancock HE
    • Journal Title

      BMC Cancer

      Volume: 10 Issue: 1 Pages: 540-540

    • DOI

      10.1186/1471-2407-10-540

    • Peer Reviewed
    • Data Source
      KAKENHI-PLANNED-20117010
  • [Journal Article] Relationship between radiosensitivity and Nrf2 target gene expression in human hematopoieic stem cells2010

    • Author(s)
      Kato K, Takahashi K, Monzen S, Yamamoto H, Mruyama A, Itoh K, Kashiwakura I
    • Journal Title

      Radiat Res

      Volume: 174 Issue: 2 Pages: 177-184

    • DOI

      10.1667/rr2146.1

    • Peer Reviewed
    • Data Source
      KAKENHI-PLANNED-20117010
  • [Journal Article] Discovery of the negative regulator of Nrf2, Keap1: A historical overview2010

    • Author(s)
      Itoh K, Mimura J, Yamamoto M
    • Journal Title

      Antioxid Redox Signal

      Volume: 120 Issue: 11 Pages: 145-154

    • DOI

      10.1089/ars.2010.3222

    • Peer Reviewed
    • Data Source
      KAKENHI-PLANNED-20117010
  • [Journal Article] Increased susceptibility of Nrf2 null mice to 1-bromopropane-induced hepatotoxicity2010

    • Author(s)
      Liu F, Ichihara S, Valentine WM, Itoh K, Yamamoto M, Mohideen SS, Kitoh J, Ichihara G
    • Journal Title

      Toxicol Sci

      Volume: 115 Issue: 2 Pages: 596-606

    • DOI

      10.1093/toxsci/kfq075

    • Peer Reviewed
    • Data Source
      KAKENHI-PLANNED-20117010, KAKENHI-PROJECT-22390120
  • [Journal Article] Ablation of the Transcription Factor Nrf2 Promotes Ischemia-Induced Neovascularization by Enhancing the Inflammatory Response2010

    • Author(s)
      Ichihara S, Yamada Y, Liu F, Murohara T, Itoh K, Yamamoto M, Ichihara G
    • Journal Title

      Arterioscler Thromb Vasc Biol

      Volume: 30 Issue: 8 Pages: 1553-1561

    • DOI

      10.1161/atvbaha.110.204123

    • Peer Reviewed
    • Data Source
      KAKENHI-PLANNED-20117010
  • [Journal Article] Role of Nrf2 in the neurotrophic action of the electrophiles2010

    • Author(s)
      Itoh K., et al
    • Journal Title

      Hirosaki Med J

      Volume: suppl.61

    • Data Source
      KAKENHI-PLANNED-20117010
  • [Journal Article] Suppression of SLC11A2 Expression Is Essential to Maintain Duodenal Integrity During Dietary Iron Overload2010

    • Author(s)
      Shirase T, Mori K, Okazaki Y, Itoh K, Yamamoto M, Tabuchi M, Kishi F, Jiang L, Akatsuka S, Nakao K, Toyokuni S
    • Journal Title

      Am J Pathol

      Volume: 177 Issue: 2 Pages: 677-685

    • DOI

      10.2353/ajpath.2010.090823

    • Peer Reviewed
    • Data Source
      KAKENHI-PLANNED-20117010
  • [Journal Article] Role of Nrf2 and p62/ZIP in the neurite outgrowth by carnosic acid in PC12h cells2010

    • Author(s)
      Kosaka K, Mimura J, Itoh K, Satoh T, Shimojo Y, Kitajima C, Maruyama A, Yamamoto M, Shirasawa T
    • Journal Title

      J Biochem

      Volume: 147 Issue: 1 Pages: 73-81

    • DOI

      10.1093/jb/mvp149

    • NAID

      10027873268

    • Peer Reviewed
    • Data Source
      KAKENHI-PLANNED-20117010
  • [Journal Article] Proteinase K-resistant alpha-synuclein is deposited in presynapses in human Lewy body disease and A53T alpha-synuclein transgenic mice2010

    • Author(s)
      Tanji K, Mori F, Mimura J, Itoh K, Kakita A, Takahashi H, Wakabayashi
    • Journal Title

      Acta Neuropathol

      Volume: 120 Issue: 2 Pages: 145-154

    • DOI

      10.1007/s00401-010-0676-z

    • Peer Reviewed
    • Data Source
      KAKENHI-PLANNED-20117010, KAKENHI-PROJECT-20300123
  • [Journal Article] Discovery of the negative regulator of Nrf2, Keap1 : A historical over view2010

    • Author(s)
      Itoh K., et al
    • Journal Title

      Antioxid Redox Signal

      Volume: 120 Pages: 145-154

    • Peer Reviewed
    • Data Source
      KAKENHI-PLANNED-20117010
  • [Journal Article] Suppression of AhR signaling pathway is associated with the downregulation of UDP-glucuronosyltransferases during BBN-induced urinary bladder carcinogenesis in mice2010

    • Author(s)
      Iida K, Mimura J, Itoh K, Ohyama C, Fujii-Kuriyama Y, Shimazui T, Akaza H and Yamamoto M
    • Journal Title

      J Biochem

      Volume: 147 Issue: 3 Pages: 353-360

    • DOI

      10.1093/jb/mvp169

    • NAID

      10027874393

    • Peer Reviewed
    • Data Source
      KAKENHI-PLANNED-20117010
  • [Journal Article] Keap1/Nrf2 system regulates neuronal survival as revealed through study of keap1 gene-knockout mice2009

    • Author(s)
      Satoh T, Harada N, Hosoya T, Tohyama K, Yamamoto M, Itoh K
    • Journal Title

      Biochem Biophys Res Commun

      Volume: 380 Issue: 2 Pages: 298-302

    • DOI

      10.1016/j.bbrc.2009.01.063

    • Peer Reviewed
    • Data Source
      KAKENHI-PLANNED-20117010
  • [Journal Article] Comparison of citrus coumarins on carcinogen-detoxifying enzymes in Nrf2 knockout mice2009

    • Author(s)
      Prince M, Li Y, Childers A, Itoh K, Yamamoto M, Kleiner HE
    • Journal Title

      Toxicol Lett

      Volume: 185 Issue: 3 Pages: 180-186

    • DOI

      10.1016/j.toxlet.2008.12.014

    • Peer Reviewed
    • Data Source
      KAKENHI-PLANNED-20117010
  • [Journal Article] Nrf2酸化ストレス応答系による病態制御2009

    • Author(s)
      伊東健
    • Journal Title

      日本生化学会誌 81巻

      Pages: 447-455

    • NAID

      10025187799

    • Data Source
      KAKENHI-PLANNED-20117010
  • [Journal Article] Nrf2/Keap1酸化ストレス応答系による活性酸素シグナル制御2009

    • Author(s)
      伊東健
    • Journal Title

      実験医学 27巻

      Pages: 225-231

    • Data Source
      KAKENHI-PLANNED-20117010
  • [Journal Article] Lansoprazole, a proton pump inhibitor, mediates anti-inflammatory effect in gastric mucosal cells through the induction of heme oxygenase-1 via activation of NF-E2-related factor 2 and oxidation of kelch-like ECH-associating protein 12009

    • Author(s)
      Takagi T, Naito Y, Okada H, Ishii T, Mizushima K, Akagiri S, Adachi S, Handa O, Kokura S, Ichikawa H, Itoh K, Yamamoto M, Matsui H, Yoshikawa T
    • Journal Title

      J Pharmacol Exp Ther

      Volume: 331 Issue: 1 Pages: 255-264

    • DOI

      10.1124/jpet.109.152702

    • Peer Reviewed
    • Data Source
      KAKENHI-PLANNED-20117010, KAKENHI-PROJECT-21390184
  • [Journal Article] Heavy ion beam irradiation regulates the mRNA expression in megakaryocytopoiesis from human hematopoietic stem/progenitor cells2009

    • Author(s)
      Monzen S, Takahashi K, Yoshino H, Kasai-Eguchi K, Abe Y, Maruyama A, Itoh K, Kashiwakura I
    • Journal Title

      Radiat Res (Tokyo)

      Volume: 50 Pages: 477-486

    • NAID

      10025912849

    • URL

      http://www.ncbi.nlm.nih.gov/pubmed/19628925

    • Peer Reviewed
    • Data Source
      KAKENHI-PLANNED-20117010
  • [Journal Article] Keap1/Nrf2 system regulates neuronal survival as revealed through study of keap1 gene-knockout mice.2009

    • Author(s)
      Satoh T, Harada N, Hosoya T, Tohyama K, Yamamoto M, Itoh K.
    • Journal Title

      Biochem Biophys Res Commun. 380

      Pages: 298-302

    • Peer Reviewed
    • Data Source
      KAKENHI-PLANNED-20117010
  • [Journal Article] Essential role of Nrf2 in keratinocyte protection from UVA by quercetin2009

    • Author(s)
      Kimura S, Warabi E, Yanagawa T, Ma D, Itoh K, Ishii Y, Kawachi Y, Ishii T
    • Journal Title

      Biochem Biophys Res Commun

      Volume: 387 Issue: 1 Pages: 109-114

    • DOI

      10.1016/j.bbrc.2009.06.136

    • Peer Reviewed
    • Data Source
      KAKENHI-PLANNED-20117010
  • [Journal Article] Transcription factor Nrf2 mediates an adaptive response to sulforaphane that protects fibroblasts in vitro against the cytotoxic effects of electrophiles, peroxides and redox-cycling agents2009

    • Author(s)
      Higgins LG, Kelleher MO, Eggleston IM, Itoh K, Yamamoto M, Hayes JD
    • Journal Title

      Toxicol Appl Pharmacol

      Volume: 237 Issue: 3 Pages: 267-280

    • DOI

      10.1016/j.taap.2009.03.005

    • Peer Reviewed
    • Data Source
      KAKENHI-PLANNED-20117010
  • [Journal Article] Nrf2 enhances cell proliferation and resistance to anticancer drugs in human lung cancer2009

    • Author(s)
      Homma S, Ishii Y, Morishima Y, Yamadori T, Matsuno Y, Haraguchi N, Kikuchi N, Satoh H, Sakamoto T, Hizawa N, Itoh K, Yamamoto M
    • Journal Title

      Clin Cancer Res

      Volume: 15 Issue: 10 Pages: 3423-3432

    • DOI

      10.1158/1078-0432.ccr-08-2822

    • Peer Reviewed
    • Data Source
      KAKENHI-PLANNED-20117010
  • [Journal Article] Nrf2 regulates the alternative first exons of CD36 in macrophages through specific antioxidant response elements2008

    • Author(s)
      Maruyama A, Tsukamoto S, Nishikawa K, Yoshida A, Harada N, Motojima K, Ishii T, Nakane A, Yamamoto M, Itoh K
    • Journal Title

      Arch Biochem Biophys

      Volume: 477 Issue: 1 Pages: 139-145

    • DOI

      10.1016/j.abb.2008.06.004

    • Peer Reviewed
    • Data Source
      KAKENHI-PLANNED-20117010
  • [Journal Article] A Possible Role of Nrf2 in Prevention of Renal Oxidative Damage by Ferric Nitrilotriacetate2008

    • Author(s)
      Kanki K, Umemura T, Kitamura Y, Ishii Y, Kuroiwa Y, Kodama Y, Itoh K, Yamamoto M, Nishikawa A, Hirose M
    • Journal Title

      Toxicol Pathol

      Volume: 36 Issue: 2 Pages: 353-361

    • DOI

      10.1177/0192623307311401

    • Peer Reviewed
    • Data Source
      KAKENHI-PLANNED-20117010
  • [Journal Article] Keap1 Regulates the Constitutive Expression of GST A1 during Differentiation of Caco-2 Cells2008

    • Author(s)
      Kusano Y, Horie S, Shibata T, Satsu H, Shimizu M, Hitomi E, Nishida M, Kurose H, Itoh K, Kobayashi A, Yamamoto M, Uchida K
    • Journal Title

      Biochemistry

      Volume: 47 Issue: 23 Pages: 6169-77

    • DOI

      10.1021/bi800199z

    • Peer Reviewed
    • Data Source
      KAKENHI-PLANNED-20117010
  • [Journal Article] Hyperglycemia induces oxidative and nitrosative stress and increases renal functional impairment in Nrf2-deficient mice2008

    • Author(s)
      Yoh K, Hirayama A, Ishizaki K, Yamada A, Takeuchi M, Yamagishi S, Morito N, Nakano T, Ojima M, Shimohata H, Itoh K, Takahashi S, Yamamoto M
    • Journal Title

      Genes Cells

      Volume: 13 Issue: 11 Pages: 1159-1170

    • DOI

      10.1111/j.1365-2443.2008.01234.x

    • Peer Reviewed
    • Data Source
      KAKENHI-PLANNED-20117010
  • [Journal Article] Transcription factor Nrf2 regulates inflammation by mediating the effect of 15-deoxy-delta^<12,14>-prostaglandin J_22004

    • Author(s)
      Itoh K.他
    • Journal Title

      Mol Cell Biol. 24

      Pages: 36-45

    • Description
      「研究成果報告書概要(和文)」より
    • Data Source
      KAKENHI-PROJECT-15310033
  • [Journal Article] Transcription factor Nrf2 regulates inflammation by mediating the effect of 15-deoxy-delta^<12,14>-prostaglandin J_22004

    • Author(s)
      Itoh K.
    • Journal Title

      Mol Cell Biol. 24

      Pages: 36-45

    • Description
      「研究成果報告書概要(欧文)」より
    • Data Source
      KAKENHI-PROJECT-15310033
  • [Presentation] Investication of relationship between GCN1 and NRF1 expression during aging in aging model mice and siRNA knockdown cells2023

    • Author(s)
      Sudarma BOGAHAWATHTHA, Tomoaki KAWAMURA, Kanade SHIGA, Goki YAMADA, Yo-Ichi NABESHIMA, Ken ITOH, Tadayuki TSUJITA
    • Organizer
      The Environmental Response VI
    • Int'l Joint Research
    • Data Source
      KAKENHI-PROJECT-23K24772
  • [Presentation] Association of mitochondrial DNA haplogroup and hearing impairment with aging in Japanese general population of the Iwaki Health Promotion Project2023

    • Author(s)
      Shiori Miura, Akira Sasaki, Shuya Kasai, Takayuki Sugawara, Yasunori Maeda, Shinichi Goto, Takashi Kasai, Nami Shimizume, Songee Jung, Takuro Iwane, Ken Itoh and Atsushi Matsubara
    • Organizer
      IFOS DUBAI ENT WORLD CONGRESS 2023
    • Int'l Joint Research
    • Data Source
      KAKENHI-PROJECT-22K09719
  • [Presentation] Identification of a Novel Aging Controller and its Competitors in an Aging Mouse Model2022

    • Author(s)
      Sudarma Bogahawaththa, Tomoaki Kawamura, Kanade Shiga, Yo-Ichi Nabeshima, Ken Itoh, Tadayuki Tsujita
    • Organizer
      第95回日本生化学会大会
    • Data Source
      KAKENHI-PROJECT-23K24772
  • [Presentation] ミトコンドリアDNAハプログループと加齢性難聴の関連 -岩木健康増進プロジェクトにおける一般地域住民での検討-2022

    • Author(s)
      佐々木亮、三浦 栞、葛西秋宅、菅原貴征、前田泰規、後藤真一、葛西 崇、清水目奈美、鄭 松伊、岩根 拓朗、伊東 健、松原 篤
    • Organizer
      第22回日本抗加齢医学会総会
    • Invited
    • Data Source
      KAKENHI-PROJECT-22K09719
  • [Presentation] Involvement of GCN1L1-GCN2 in mitochondrial dysfunction-induced ATF4 activation2019

    • Author(s)
      Shuya Kasai, Ken Itoh
    • Organizer
      Keystone symposia, Mitochondrial Biology
    • Int'l Joint Research
    • Data Source
      KAKENHI-PLANNED-26111010
  • [Presentation] Ribosome binding protein GCN1L1 controls cell cycle and is essential for embryonic development2019

    • Author(s)
      Hiromi Yamazaki, Shuya Kasai, Junsei Mimura, Peng Ye, Atsushi Inose Maruyama, Ken Itoh
    • Organizer
      9th Federation of the Asian and Oceanian Physiological Societieds
    • Int'l Joint Research
    • Data Source
      KAKENHI-PLANNED-26111010
  • [Presentation] Prevention of Age-related Degenerative Diseases by Nrf2-based Early Intervention.2018

    • Author(s)
      Itoh K.
    • Organizer
      WCP2018 KYOTO
    • Int'l Joint Research
    • Data Source
      KAKENHI-PLANNED-26111010
  • [Presentation] ROLE OF GCN1L1 IN MAMMALIAN MITOCHONDRIAL QUALITY CONTROL2018

    • Author(s)
      KEN ITOH, SHUYA KASAI
    • Organizer
      Targetting Mitochondria 2018
    • Int'l Joint Research
    • Data Source
      KAKENHI-PLANNED-26111010
  • [Presentation] Nrf2とATF4の相互作用を基盤にした加齢性変性疾患予防法の開発2017

    • Author(s)
      伊東健
    • Organizer
      第14回レドックス・ライフイノベーションシンポジウム
    • Data Source
      KAKENHI-PLANNED-26111010
  • [Presentation] マウス発生におけるリボソーム結合性因子GCN1L1の役割2017

    • Author(s)
      山嵜博未、叶鵬、葛西秋宅、 三村純正、 猪瀬-丸山敦史、伊東健
    • Organizer
      2017年度生命科学系学会合同年次大会
    • Int'l Joint Research
    • Data Source
      KAKENHI-PROJECT-25293064
  • [Presentation] Nrf2経路とATF4経路の協調作用2017

    • Author(s)
      三村純正、伊東 健
    • Organizer
      2017年度生命科学系学会合同年次大会
    • Int'l Joint Research
    • Data Source
      KAKENHI-PROJECT-25293064
  • [Presentation] ミトコンドリア統合的ストレス応答におけるGCN1L1-GCN2の関与2017

    • Author(s)
      葛西秋宅、伊東健
    • Organizer
      2017年度生命科学系学会合同年次大会
    • Int'l Joint Research
    • Data Source
      KAKENHI-PROJECT-25293064
  • [Presentation] Nrf2とATF4の相互作用を基盤にした加齢性変性疾患予防法の開発2017

    • Author(s)
      伊東健
    • Organizer
      第14回レドックス・ライフイノベーションシンポジウム
    • Invited
    • Data Source
      KAKENHI-PROJECT-25293064
  • [Presentation] 酸化ストレス鍵転写因子Nrf2の生理的役割・進化論的意義と疾患予防2016

    • Author(s)
      伊東健
    • Organizer
      第69回日本酸化ストレス学会学術集会
    • Place of Presentation
      仙台国際センター(宮城県仙台市)
    • Year and Date
      2016-08-30
    • Invited
    • Data Source
      KAKENHI-PLANNED-26111010
  • [Presentation] Nrf2を中心とした転写因子ネットワークの活性化を利用した食品機能性成分による脳神経変性疾患予防戦略2016

    • Author(s)
      伊東健
    • Organizer
      第7回岐阜薬科大学機能性健康食品(蜂産品)研究講演会
    • Place of Presentation
      じゅうろくプラザ(岐阜県、岐阜市)
    • Invited
    • Data Source
      KAKENHI-PROJECT-25293064
  • [Presentation] Nrf2とeIF2α-ATF4ストレス応答経路のクロストークによるレドックス応答機構2016

    • Author(s)
      伊東健
    • Organizer
      第58回歯科基礎医学会学術大会
    • Place of Presentation
      札幌コンベンションセンター(北海道札幌市)
    • Year and Date
      2016-08-24
    • Data Source
      KAKENHI-PLANNED-26111010
  • [Presentation] Nrf2を中心とした転写因子ネットワークによる疾患制御2016

    • Author(s)
      伊東健
    • Organizer
      第37回日本循環制御医学会総会
    • Place of Presentation
      ステーションコンファレンス東京(東京都)
    • Year and Date
      2016-07-08
    • Data Source
      KAKENHI-PROJECT-25293064
  • [Presentation] 酸化ストレス鍵転写因子Nrf2の生理的役割・進化論的意義と疾患予防2016

    • Author(s)
      伊東健
    • Organizer
      第69回日本酸化ストレス学会学術集会
    • Place of Presentation
      仙台国際センター(宮城県、仙台市)
    • Year and Date
      2016-08-30
    • Invited
    • Data Source
      KAKENHI-PROJECT-25293064
  • [Presentation] Nrf2とeIF2α-ATF4ストレス応答経路のクロストークによるレドックス応答機構2016

    • Author(s)
      伊東健
    • Organizer
      第58回歯科基礎医学会学術大会
    • Place of Presentation
      札幌コンべンションセンター(北海道、札幌市)
    • Year and Date
      2016-08-24
    • Data Source
      KAKENHI-PROJECT-25293064
  • [Presentation] Elucidation of Nrf2-centered transcriptional network toward the disease prevention and therapy2016

    • Author(s)
      Ken Itoh
    • Organizer
      第89回日本生化学会大会
    • Place of Presentation
      仙台国際センター(宮城県、仙台市)
    • Year and Date
      2016-09-25
    • Int'l Joint Research
    • Data Source
      KAKENHI-PROJECT-25293064
  • [Presentation] Elucidation of Nrf2-centered transcriptional network toward the disease prevention and therapy2016

    • Author(s)
      Ken Itoh
    • Organizer
      第89回日本生化学会大会
    • Place of Presentation
      仙台国際センター(宮城県仙台市)
    • Year and Date
      2016-09-25
    • Int'l Joint Research
    • Data Source
      KAKENHI-PLANNED-26111010
  • [Presentation] Elucidation of Nrf2-centered transcriptional network toward the development of novel neuroprotective strategy2016

    • Author(s)
      Ken Itoh
    • Organizer
      第9回国際NO学会
    • Place of Presentation
      仙台国際センター(宮城県仙台市)
    • Year and Date
      2016-05-20
    • Invited / Int'l Joint Research
    • Data Source
      KAKENHI-PLANNED-26111010
  • [Presentation] Nrf2を中心とした転写因子ネットワークの活性化を利用した食品機能性成分による脳神経変性疾患予防戦略2016

    • Author(s)
      伊東健
    • Organizer
      第7回岐阜薬科大学機能性健康食品(蜂産品)研究講演会
    • Place of Presentation
      じゅうろくプラザ(岐阜県岐阜市)
    • Invited
    • Data Source
      KAKENHI-PLANNED-26111010
  • [Presentation] Elucidation of Nrf2-centered transcriptional network toward the development of novel neuroprotective strategy2016

    • Author(s)
      Ken Itoh
    • Organizer
      第9回国際NO学会
    • Place of Presentation
      仙台国際センター(宮城県、仙台市)
    • Year and Date
      2016-05-20
    • Int'l Joint Research
    • Data Source
      KAKENHI-PROJECT-25293064
  • [Presentation] Nrf2を中心とした転写因子ネットワークによる疾患制御2016

    • Author(s)
      伊東健
    • Organizer
      第37回日本循環制御医学会総会
    • Place of Presentation
      ステーションコンファランス東京(東京都)
    • Year and Date
      2016-07-08
    • Data Source
      KAKENHI-PLANNED-26111010
  • [Presentation] Carnosic acid transcriptionally induces genes related to glutathione synthesis by the concomitant activation of ATF4 and Nrf2.2015

    • Author(s)
      Mimura J, Kosaka K, Itoh K.
    • Organizer
      ISANH Antioxidant World Congress
    • Place of Presentation
      France, Paris
    • Year and Date
      2015-06-22
    • Int'l Joint Research
    • Data Source
      KAKENHI-PROJECT-25293064
  • [Presentation] Carnosic acid activates ATF4 signaling pathway2015

    • Author(s)
      三村純正,丸山敦史,小坂邦男,伊東健
    • Organizer
      第38回日本分子生物学会年会
    • Place of Presentation
      ポートアイランド(兵庫県・神戸市)
    • Year and Date
      2015-12-01
    • Data Source
      KAKENHI-PROJECT-25293064
  • [Presentation] SCREENING OF MITOPHAGY INDUCERS IN HELA CELLS.2015

    • Author(s)
      Yamazaki H, Itoh K
    • Organizer
      The 6th World Congress on Targeting Mitochondria
    • Place of Presentation
      Deutschland, Berlin
    • Year and Date
      2015-10-28
    • Int'l Joint Research
    • Data Source
      KAKENHI-PROJECT-25293064
  • [Presentation] SCREENING OF MITOPHAGY INDUCERS IN HELA CELLS.2015

    • Author(s)
      Yamazaki H, Itoh K
    • Organizer
      The 6th World Congress on Targeting Mitochondria
    • Place of Presentation
      Deutschland, Berlin
    • Year and Date
      2015-10-28
    • Int'l Joint Research
    • Data Source
      KAKENHI-PLANNED-26111010
  • [Presentation] Carnosic acid activates ATF4 signaling pathway2015

    • Author(s)
      三村純正、丸山敦史、小坂邦男、伊東健
    • Organizer
      BMB 2015
    • Place of Presentation
      ポートアイランド(兵庫県・神戸市)
    • Year and Date
      2015-12-01
    • Data Source
      KAKENHI-PLANNED-26111010
  • [Presentation] Carnosic acid transcriptionally induces genes related to glutathione synthesis by the concomitant activation of ATF4 and Nrf2.a2015

    • Author(s)
      Mimura J, Kosaka K, Itoh K.
    • Organizer
      ISANH Antioxidant World Congress
    • Place of Presentation
      France, Paris
    • Year and Date
      2015-06-22
    • Int'l Joint Research
    • Data Source
      KAKENHI-PLANNED-26111010
  • [Presentation] Associated gene regulation by long non-coding RNA transcribed from heme oxygenase-1 E2 enhancer region2015

    • Author(s)
      Maruyama A, Itoh K.
    • Organizer
      BMB2015
    • Place of Presentation
      Port Island (Hyogo, Kobe)
    • Year and Date
      2015-12-01
    • Data Source
      KAKENHI-PROJECT-25293064
  • [Presentation] Nrf2-FPN1経路を介した抗炎症の分子機構の解析2015

    • Author(s)
      伊東健
    • Organizer
      第38回日本分子生物学会年会
    • Place of Presentation
      ポートアイランド(兵庫県・神戸市)
    • Year and Date
      2015-12-01
    • Data Source
      KAKENHI-PROJECT-25293064
  • [Presentation] Activation of ATF4 signaling pathway by carnosic acid.2014

    • Author(s)
      Mimura J, Maruyama A, Kosaka K, Itoh K.
    • Organizer
      17th Bennial Meeting of Society for Free Radical Research International
    • Place of Presentation
      Kyoto
    • Data Source
      KAKENHI-PROJECT-25293064
  • [Presentation] The role of ribosomal interacting protein GCN1L1 in oxidative stress-mediated Nrf2 activation2014

    • Author(s)
      Liu T, Kimura S, Yamazaki H, Maruyama A, Nishikawa K, Harada N, Mimura J, Yamamoto M, Itoh K
    • Organizer
      17th Bennial Meeting of Society for Free Radical Research International
    • Place of Presentation
      Kyoto International Conference Center, Kyoto
    • Data Source
      KAKENHI-PROJECT-24659122
  • [Presentation] リボソーム結合因子GCN1L1および転写因子ATF4との相互作用によるNrf2応答機構の調節機構2014

    • Author(s)
      伊東健.
    • Organizer
      基盤S公開シンポジウム「レドックス制御」
    • Place of Presentation
      つくば
    • Year and Date
      2014-10-27
    • Data Source
      KAKENHI-PLANNED-26111010
  • [Presentation] The role of ribosomal interacting protein GCN1L1 in oxidative stress-mediated Nrf2 activation.2014

    • Author(s)
      Liu T, Kimura S, Yamazaki H, Maruyama A, Nishikawa K, Harada N, Mimura J, Yamamoto M, Itoh K.
    • Organizer
      17th Bennial Meeting of Society for Free Radical Research International
    • Place of Presentation
      Kyoto
    • Data Source
      KAKENHI-PROJECT-25293064
  • [Presentation] Emerging molecular mechanisms of Nrf2-mediated gene induction2014

    • Author(s)
      Itoh K
    • Organizer
      The Environmental Response IV
    • Place of Presentation
      Sendai
    • Invited
    • Data Source
      KAKENHI-PROJECT-24659122
  • [Presentation] The mechanism of human xCT gene induction by proteasome inhibitors.2014

    • Author(s)
      Ye P, Mimura J, Itoh K
    • Organizer
      17th Bennial Meeting of Society for Free Radical Research International
    • Place of Presentation
      Kyoto
    • Data Source
      KAKENHI-PROJECT-25293064
  • [Presentation] Emerging molecular mechanisms of Nrf2-mediated gene induction2014

    • Author(s)
      Itoh K
    • Organizer
      The Environmental Response IV
    • Place of Presentation
      Sendai
    • Invited
    • Data Source
      KAKENHI-PROJECT-25293064
  • [Presentation] The role of ribosomal interacting protein GCN1L1 in oxidative stress-mediated Nrf2 activation2014

    • Author(s)
      Liu T, Kimura S, Yamazaki H, Maruyama A, Nishikawa K, Harada N, Mimura J, Yamamoto M, Itoh K.
    • Organizer
      17th Bennial Meeting of Society for Free Radical Research International. Kyoto International Conference Center
    • Place of Presentation
      Kyoto
    • Data Source
      KAKENHI-PROJECT-24659122
  • [Presentation] Nrf2転写調節経路とeIF2αリン酸化経路とのクロストーク2013

    • Author(s)
      伊東健
    • Organizer
      日本放射線影響学会第56回大会
    • Place of Presentation
      青森市
    • Invited
    • Data Source
      KAKENHI-PROJECT-24659122
  • [Presentation] 酸化ストレスで活性化する転写経路のクロストーク2013

    • Author(s)
      伊東健
    • Organizer
      第102回日本病理学会総会
    • Place of Presentation
      札幌市
    • Invited
    • Data Source
      KAKENHI-PROJECT-25293064
  • [Presentation] Nrf2転写調節経路とeIF2αリン酸化経路とのクロストーク2013

    • Author(s)
      伊東健
    • Organizer
      日本放射線影響学会
    • Place of Presentation
      青森市
    • Invited
    • Data Source
      KAKENHI-PROJECT-25293064
  • [Presentation] 酸化ストレスで活性化する転写経路のクロストーク2013

    • Author(s)
      伊東健
    • Organizer
      第102回日本病理学会総会
    • Place of Presentation
      ロイトン札幌,札幌
    • Data Source
      KAKENHI-PROJECT-24659122
  • [Presentation] Nrf2転写調節経路とeIF2aリン酸化経路とのクロストーク2013

    • Author(s)
      伊東健
    • Organizer
      日本放射線影響学会第56回大会
    • Place of Presentation
      ホテルクラウンパレス,青森
    • Data Source
      KAKENHI-PROJECT-24659122
  • [Presentation] 酸化ストレスで活性化する転写経路のクロストーク2013

    • Author(s)
      伊東健
    • Organizer
      第102回日本病理学会総会
    • Place of Presentation
      札幌市
    • Invited
    • Data Source
      KAKENHI-PROJECT-24659122
  • [Presentation] Nrf2を介した抗酸化・抗炎症機構による病態制御2013

    • Author(s)
      伊東健
    • Organizer
      第30回臨床フリーラジカル会議
    • Place of Presentation
      京都
    • Invited
    • Data Source
      KAKENHI-PROJECT-24659122
  • [Presentation] Nrf2を介した抗酸化・抗炎症機構による病態制御2013

    • Author(s)
      伊東健
    • Organizer
      第30回臨床フリーラジカル会議
    • Place of Presentation
      京都
    • Invited
    • Data Source
      KAKENHI-PROJECT-25293064
  • [Presentation] Nrf2 in the bone marrow-derived cells is essential for the high-fat diet induced atherosclerotic plaque formation2012

    • Author(s)
      Ken Itoh
    • Organizer
      37th FEBS meeting
    • Place of Presentation
      Seville Conference and Exhibition Center (Seville)
    • Data Source
      KAKENHI-PROJECT-24659122
  • [Presentation] The role of ribosome interacting protein GCN1L1 in oxidative stress-mediated Nrf2 activation2012

    • Author(s)
      Itoh K
    • Organizer
      Functions of Reactive Oxygen Species, Grants-in-Aid for Scientific Research on Innovative Areas, MEXT
    • Place of Presentation
      Kyushu University, Fukuoka, Japan
    • Year and Date
      2012-12-17
    • Data Source
      KAKENHI-ORGANIZER-20117001
  • [Presentation] The role of ribosome intera-cting protein GCN1L1 in oxidative stress-mediated Nrf2 activation. International symposium 2012 on Signaling2012

    • Author(s)
      Ken Itoh
    • Organizer
      Function of Reactive Oxygen Species
    • Place of Presentation
      Kyushu University Station-I for Collaboration Research (Fukuoka)
    • Year and Date
      2012-12-17
    • Data Source
      KAKENHI-PLANNED-20117010
  • [Presentation] Nrf2 in the bone marrow-derived cells is essential for the high-fat diet induced atherosclerotic plaque formation2012

    • Author(s)
      Ken Itoh
    • Organizer
      37th FEBS meeting
    • Place of Presentation
      Seville Conference and Exhibition Center (Seville)
    • Year and Date
      2012-09-04
    • Data Source
      KAKENHI-PLANNED-20117010
  • [Presentation] Nrf2 in the bone marrow-derived cells contributes to the high-fat diet induced atherosclerotic plaque formation2012

    • Author(s)
      Ken Itoh, et al.
    • Organizer
      THE 33^<RD> NAITO CONFERENCE ON Oxygen Biology: Hypoxia, Oxidative Stress and Diseases
    • Place of Presentation
      CHATERAISE Gateaux Kingdom SAPPORO, Sapporo
    • Data Source
      KAKENHI-PLANNED-20117010
  • [Presentation] Nrf2 in the bone marrow-derived cells is essential for the high-fat diet induced atherosclerotic plaque formation2012

    • Author(s)
      Ken Itoh, et al.
    • Organizer
      UK-Japan Research Symposium Molecular Mechanisms of Stress Response in Disease
    • Place of Presentation
      Science Information Center, Tsukuba
    • Data Source
      KAKENHI-PLANNED-20117010
  • [Presentation] The role of ribosome interacting protein GCN1L1 in oxidative stress -mediated Nrf2 activation2012

    • Author(s)
      Ken Itoh
    • Organizer
      International symposium 2012 on Signaling Function of Reactive Oxygen Species
    • Place of Presentation
      Kyushu University Station-I for Collaboration Research (Fukuoka)
    • Data Source
      KAKENHI-PROJECT-24659122
  • [Presentation] Nrf2 in the bone marrow-derived cells is essential for the high-fat diet induced atherosclerotic plaque formation2012

    • Author(s)
      Ken Itoh, et al.
    • Organizer
      37^<th> FEBS meeting
    • Place of Presentation
      Seville Conference and Exhibition Center (Seville, Spain)
    • Data Source
      KAKENHI-PLANNED-20117010
  • [Presentation] アミノ酸飢餓応答因子GCN1L1によるNrf2活性制御機構の解析2012

    • Author(s)
      伊東健
    • Organizer
      第82回日本生化学会大会
    • Place of Presentation
      福岡国際会議場 (福岡)
    • Year and Date
      2012-12-14
    • Data Source
      KAKENHI-PLANNED-20117010
  • [Presentation] アミノ酸飢餓応答因子GCN1L1によるNrf2活性制御機構の解析2012

    • Author(s)
      伊東健、他
    • Organizer
      第82回日本生化学会大会
    • Place of Presentation
      福岡国際会議場(福岡)
    • Data Source
      KAKENHI-PLANNED-20117010
  • [Presentation] The role of ribosome interacting protein GCN1L1 in oxidative stress-mediated Nrf2 activation2012

    • Author(s)
      Ken Itoh
    • Organizer
      International symposium 2012 on Signaling Function of Reactive Oxygen Species
    • Place of Presentation
      Kyushu University Station-I for Collaboration Research (Fukuoka)
    • Invited
    • Data Source
      KAKENHI-PLANNED-20117010
  • [Presentation] アミノ酸飢餓応答因子GCN1L1によるNrf2活性制御機構の解析2012

    • Author(s)
      伊東健、 他
    • Organizer
      第82回日本生化学会大会
    • Place of Presentation
      福岡国際会議場 (福岡)
    • Data Source
      KAKENHI-PROJECT-24659122
  • [Presentation] The role of ribosome interac ti-ng protein GCN1L1 in oxidative stre ss-mediated Nrf2 activation2012

    • Author(s)
      Ken Itoh
    • Organizer
      Internati onal symposium 2012 on Signaling, Func tion of Reactive Oxygen Species
    • Place of Presentation
      Kyushu University Station -I for Collaboration Research (Fukuoka)
    • Year and Date
      2012-12-17
    • Data Source
      KAKENHI-PROJECT-24659122
  • [Presentation] Redox sensitive transcription factor Nrf2 regulates Fpn1-mediatediron efflux and counteracts the inflammation-mediated Fpn1 mRNA suppression2011

    • Author(s)
      Itoh K., et al
    • Organizer
      36^<th> FEBS congress
    • Place of Presentation
      Torino
    • Year and Date
      2011-06-27
    • Data Source
      KAKENHI-PLANNED-20117010
  • [Presentation] 慢性炎症、酸化ストレスとNrf22011

    • Author(s)
      伊東健
    • Organizer
      第35回鉄バイオサイエンス学会学術集会
    • Place of Presentation
      徳島
    • Year and Date
      2011-09-11
    • Data Source
      KAKENHI-PLANNED-20117010
  • [Presentation] Redox-sensitive transcription factor Nrf2 regulates Fpn1-mediated iron efflux and counteracts LPS-mediated Fpn1 mRNA suppression2011

    • Author(s)
      Ken Itoh
    • Organizer
      36^<th> FEBS CONGRESS Biochemistry for Tomorrow's Medicine
    • Place of Presentation
      Torino Italy
    • Data Source
      KAKENHI-PLANNED-20117010
  • [Presentation] Nrf2はヒトHO-1遺伝子プロモーター領域のZ-DNA形成を誘導する2010

    • Author(s)
      丸山 敦史、伊東 健
    • Organizer
      第83回日本生化学会大会
    • Place of Presentation
      神戸ポートアイランド、神戸
    • Data Source
      KAKENHI-PLANNED-20117010
  • [Presentation] Nitric oxide responsive transcription factor Nrf2 regulates Fpn1-mediated iron efflux and counteracts the inflammation-mediated Fpn1 mRNA suppression2010

    • Author(s)
      Itoh K., et al
    • Organizer
      The 6^<th> international conference on the biology, chemistry, and therapeutic application of nitric oxide
    • Place of Presentation
      Kyoto
    • Year and Date
      2010-06-14
    • Data Source
      KAKENHI-PLANNED-20117010
  • [Presentation] Role of Nrf2 in the Neurotropic Action of Electrophiles2010

    • Author(s)
      Ken Itoh
    • Organizer
      The 9^<th> International Symposium on 'Recent Trends in Pharmaceutical Sciences', February 4 2010
    • Place of Presentation
      Institute for Drug Research Yeungnam University, Gyeongsan, Korea
    • Year and Date
      2010-02-04
    • Data Source
      KAKENHI-PLANNED-20117010
  • [Presentation] Role of Nrf2 in the neurotrophic action of the electrophiles2010

    • Author(s)
      伊東健
    • Organizer
      The 9^<th> International Symposium on Recent Trends in Pharmaceutical Sciences
    • Place of Presentation
      Yeungnam University(Miami)
    • Year and Date
      2010-02-04
    • Data Source
      KAKENHI-PLANNED-20117010
  • [Presentation] Nrf2はヒトHO-1遺伝子プロモーター領域のZ-DNA形成を誘導する2010

    • Author(s)
      丸山敦史、伊東健
    • Organizer
      第83回日本生化学会大会
    • Place of Presentation
      神戸ポートアイランド
    • Data Source
      KAKENHI-PLANNED-20117010
  • [Presentation] Nrf2-HO-1経路の制御機構と生理機能2009

    • Author(s)
      伊東 健
    • Organizer
      第6回Heme Oxygenase研究フオーラム
    • Place of Presentation
      京都府立大学・青蓮会館、京都
    • Year and Date
      2009-08-28
    • Data Source
      KAKENHI-PLANNED-20117010
  • [Presentation] Nrf2経路を介した活性酸素シグナル制御機構の解析2009

    • Author(s)
      伊東 健
    • Organizer
      第82回日本生化学会大会
    • Place of Presentation
      神戸ポートアイランド、神戸
    • Data Source
      KAKENHI-PLANNED-20117010
  • [Presentation] Role of Nrf2 in neural protection and differentiation2009

    • Author(s)
      Ken Itoh
    • Organizer
      SFRR International Free Radical School in Japan, 2009
    • Place of Presentation
      JOETSU KOKUSAI SKI RESORT, Echigoyuzawa
    • Data Source
      KAKENHI-PLANNED-20117010
  • [Presentation] Nrf2-HO-1経路の制御機構と生理機能2009

    • Author(s)
      伊東健
    • Organizer
      第6回Heme Oxygenase研究フオーラム
    • Place of Presentation
      京都府立大学・青蓮会館
    • Year and Date
      2009-08-28
    • Data Source
      KAKENHI-PLANNED-20117010
  • [Presentation] Nrf2 co-activator for HO-1 regulation2009

    • Author(s)
      伊東健
    • Organizer
      Heme oxygenase in biology & medicine
    • Place of Presentation
      Miami Beach Resor, Spa(Miami)
    • Year and Date
      2009-10-01
    • Data Source
      KAKENHI-PLANNED-20117010
  • [Presentation] Nrf2経路を介した活性酸素シグナル制御機構の解析2009

    • Author(s)
      伊東健
    • Organizer
      第82回日本生化学会大会
    • Place of Presentation
      神戸ポートアイランド
    • Data Source
      KAKENHI-PLANNED-20117010
  • [Presentation] Elucidation of Nrf2-mediated Transactivation Mechanisms2009

    • Author(s)
      Ken Itoh
    • Place of Presentation
      Gonryo-kaikan in Tohoku University, Sendai
    • Data Source
      KAKENHI-PLANNED-20117010
  • [Presentation] Nrf2 co-activator for HO-1 gene regulation2009

    • Author(s)
      Ken Itoh
    • Organizer
      6^<th> International Congress on Heme Oxygenases
    • Place of Presentation
      Miami Beach, Florida, USA
    • Data Source
      KAKENHI-PLANNED-20117010
  • [Presentation] Nrf2経路を介した活性酸素シグナル制御機構の解析2009

    • Author(s)
      伊東健
    • Organizer
      第82回日本生化学会
    • Place of Presentation
      神戸ポートアイランド(神戸)
    • Year and Date
      2009-10-23
    • Data Source
      KAKENHI-PLANNED-20117010
  • [Presentation] Nrf2-HO-1経路の制御機構と生理機能2009

    • Author(s)
      伊東健
    • Organizer
      第6回 Heme Oxygenase 研究フオーラム
    • Place of Presentation
      京都府立医科大学・青蓮会館(京都)
    • Year and Date
      2009-08-28
    • Data Source
      KAKENHI-PLANNED-20117010
  • [Presentation] Role of Nrf2 in neural protection and differentiation.2009

    • Author(s)
      Ken Itoh.
    • Organizer
      SFRR International Free Radical School in Japan, 2009.
    • Place of Presentation
      JOETSU KOKUSAI SKI RESORT.
    • Data Source
      KAKENHI-PLANNED-20117010
  • [Presentation] Role of Nrf2 in neural protection and differentiation2009

    • Author(s)
      伊東健
    • Organizer
      SFRR International Free Radical School in Japan 2009
    • Place of Presentation
      JOETSU KOKUSAI RESORT(Yuzawa)
    • Year and Date
      2009-09-03
    • Data Source
      KAKENHI-PLANNED-20117010
  • [Presentation] Nrf2 co-activator for HO-1 gene regulation.2009

    • Author(s)
      Ken Itoh.
    • Organizer
      6th International Congress on Heme Oxygenases.
    • Place of Presentation
      Miami Beach, Florida.
    • Data Source
      KAKENHI-PLANNED-20117010
  • [Presentation] Specific roles of BRG1 and actin-related motif in Nrf2 mediated heme oxygenase-1 induction2008

    • Author(s)
      Itoh K, et.al.
    • Organizer
      BMB2008
    • Place of Presentation
      Kobe
    • Year and Date
      2008-12-11
    • Data Source
      KAKENHI-PROJECT-20052001
  • [Presentation] Specific roles of BRG1 and actin-related motif in Nrf 2 mediated heme oxygenase-1 induction2008

    • Author(s)
      Itoh K, et.al.
    • Organizer
      BMB2008
    • Place of Presentation
      Kobe
    • Year and Date
      2008-12-11
    • Data Source
      KAKENHI-PLANNED-20117010
  • [Presentation] Specific roles of BRG1 and actin-related motif in Nrf2 mediated heme oxygenase-1 induction2008

    • Author(s)
      Ken Itoh, et al.
    • Organizer
      BMB2008
    • Place of Presentation
      Port Island KOBE, Kobe
    • Year and Date
      2008-12-11
    • Data Source
      KAKENHI-PLANNED-20117010
  • [Presentation] Functional role of enhancer RNA derived from human HO-1 enhancer regions for HO-1 gene induction

    • Author(s)
      Maruyama A, Mimura J, Itoh K.
    • Organizer
      8th International Conference on Heme Oxygenases
    • Place of Presentation
      Sydney
    • Year and Date
      2014-10-08 – 2014-10-11
    • Data Source
      KAKENHI-PROJECT-25293064
  • [Presentation] Functional role of eRNAs derived from human HO-1 enhancer regions for HO-1 gene induction.

    • Author(s)
      Maruyma A, Mimura J, Itoh K.
    • Organizer
      IIAS Research Conference 2014 Choromatin Decoding
    • Place of Presentation
      Kyoto
    • Year and Date
      2014-05-12 – 2014-05-15
    • Data Source
      KAKENHI-PROJECT-25293064
  • [Presentation] Nrf2 regulates NGF mRNA expression in human glioma cells and normal human astrocytes.

    • Author(s)
      Mimura J, Yoshida H, Kosaka K, Itoh K.
    • Organizer
      The 2014 Alzhimer’s Disease Congress
    • Place of Presentation
      London
    • Year and Date
      2014-06-23 – 2014-06-25
    • Data Source
      KAKENHI-PROJECT-25293064
  • [Presentation] Nrf2- and ATF4-dependent up-regulation of xCT modulates the sensitivity of T24 bladder carcinoma cells to proteasome inhibition

    • Author(s)
      Ye P, Mimura J, Okada T, Sato H, Liu T, Maruyama A, Ohyama C, Itoh K.
    • Organizer
      The 87th Annual Meeting of the Japanese Biochemical Society
    • Place of Presentation
      Kyoto
    • Year and Date
      2014-10-15 – 2014-10-18
    • Data Source
      KAKENHI-PROJECT-25293064
  • [Presentation] Nrf2- and ATF4-dependent up-regulation of xCT modulates the sensitivity of T24 bladder carcinoma cells to proteasome inhibition

    • Author(s)
      Ye P, Mimura J, Okada T, Sato H, Liu T, Maruyama A, Ohyama C, Itoh K.
    • Organizer
      8th International Conference on Heme Oxygenases
    • Place of Presentation
      Kyoto
    • Year and Date
      2014-10-15 – 2014-10-18
    • Data Source
      KAKENHI-PLANNED-26111010
  • [Presentation] Development of a novel neuroprotective strategy by the cooperative transcriptional network centered on Nrf2.

    • Author(s)
      Itoh K.
    • Organizer
      SFRBM Annual meeting 2014
    • Place of Presentation
      Seattle
    • Year and Date
      2014-11-19 – 2014-11-23
    • Data Source
      KAKENHI-PROJECT-25293064
  • [Presentation] Development of a novel neuroprotective strategy by the cooperative transcriptional network centered on Nrf2

    • Author(s)
      Itoh K.
    • Organizer
      SFRBM Annual meeting 2014
    • Place of Presentation
      Seattle
    • Year and Date
      2014-11-19 – 2014-11-23
    • Invited
    • Data Source
      KAKENHI-PLANNED-26111010
  • 1.  MIMURA Junsei (60344884)
    # of Collaborated Projects: 3 results
    # of Collaborated Products: 29 results
  • 2.  MARUYAMA Atsushi (10431438)
    # of Collaborated Projects: 2 results
    # of Collaborated Products: 22 results
  • 3.  AKAIKE Takaaki (20231798)
    # of Collaborated Projects: 1 results
    # of Collaborated Products: 0 results
  • 4.  SUMIMOTO Hideki (30179303)
    # of Collaborated Projects: 1 results
    # of Collaborated Products: 0 results
  • 5.  UCHIDA Koji (40203533)
    # of Collaborated Projects: 1 results
    # of Collaborated Products: 0 results
  • 6.  MATSUMOTO Akio (60437308)
    # of Collaborated Projects: 1 results
    # of Collaborated Products: 0 results
  • 7.  URANO Yasuteru (20292956)
    # of Collaborated Projects: 1 results
    # of Collaborated Products: 0 results
  • 8.  ARIMOTO Hirokazu (60262789)
    # of Collaborated Projects: 1 results
    # of Collaborated Products: 0 results
  • 9.  SHIMOKAWA Hiroaki (00235681)
    # of Collaborated Projects: 1 results
    # of Collaborated Products: 0 results
  • 10.  TSUTSUI Hiroyuki (70264017)
    # of Collaborated Projects: 1 results
    # of Collaborated Products: 0 results
  • 11.  UEHARA Takashi (00261321)
    # of Collaborated Projects: 1 results
    # of Collaborated Products: 0 results
  • 12.  KAMATA Hideaki (10233925)
    # of Collaborated Projects: 1 results
    # of Collaborated Products: 0 results
  • 13.  NISHIDA Motohiro (90342641)
    # of Collaborated Projects: 1 results
    # of Collaborated Products: 0 results
  • 14.  SATOH Takumi (10300831)
    # of Collaborated Projects: 1 results
    # of Collaborated Products: 7 results
  • 15.  HIMENO Hyouta (80208785)
    # of Collaborated Projects: 1 results
    # of Collaborated Products: 0 results
  • 16.  ISHII Tetsuro (20111370)
    # of Collaborated Projects: 1 results
    # of Collaborated Products: 0 results
  • 17.  KUMAGAI Yoshito (00250100)
    # of Collaborated Projects: 1 results
    # of Collaborated Products: 0 results
  • 18.  YANAGAWA Toru (10312852)
    # of Collaborated Projects: 1 results
    # of Collaborated Products: 0 results
  • 19.  WARABI Eiji (70396612)
    # of Collaborated Projects: 1 results
    # of Collaborated Products: 1 results
  • 20.  松宮 朋穂 (30344592)
    # of Collaborated Projects: 1 results
    # of Collaborated Products: 1 results
  • 21.  鈴木 隆史 (70508308)
    # of Collaborated Projects: 1 results
    # of Collaborated Products: 0 results
  • 22.  濱崎 純 (80533588)
    # of Collaborated Projects: 1 results
    # of Collaborated Products: 0 results
  • 23.  本橋 ほづみ (00282351)
    # of Collaborated Projects: 1 results
    # of Collaborated Products: 0 results
  • 24.  佐々木 亮 (20451479)
    # of Collaborated Projects: 1 results
    # of Collaborated Products: 2 results
  • 25.  後藤 真一 (10833577)
    # of Collaborated Projects: 1 results
    # of Collaborated Products: 3 results
  • 26.  辻田 忠志 (20622046)
    # of Collaborated Projects: 1 results
    # of Collaborated Products: 2 results
  • 27.  植村 武史 (50401005)
    # of Collaborated Projects: 1 results
    # of Collaborated Products: 0 results
  • 28.  TAGUCHI Keiko
    # of Collaborated Projects: 0 results
    # of Collaborated Products: 1 results
  • 29.  KATSUOKA Fumiki
    # of Collaborated Projects: 0 results
    # of Collaborated Products: 1 results
  • 30.  山本 雅之
    # of Collaborated Projects: 0 results
    # of Collaborated Products: 6 results
  • 31.  坂井 詠子
    # of Collaborated Projects: 0 results
    # of Collaborated Products: 1 results
  • 32.  岡元 邦彰
    # of Collaborated Projects: 0 results
    # of Collaborated Products: 1 results
  • 33.  西下 一久
    # of Collaborated Projects: 0 results
    # of Collaborated Products: 1 results
  • 34.  筑波 隆幸
    # of Collaborated Projects: 0 results
    # of Collaborated Products: 1 results
  • 35.  葛西 秋宅
    # of Collaborated Projects: 0 results
    # of Collaborated Products: 1 results
  • 36.  山嵜 博未
    # of Collaborated Projects: 0 results
    # of Collaborated Products: 2 results
  • 37.  佐藤 英世
    # of Collaborated Projects: 0 results
    # of Collaborated Products: 1 results

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