ADACHI Mimi 安達三美

… Alternative Names

Researcher Number	10323693
Other IDs
Affiliation (Current)	2022: 帝京大学, 医学部, 教授
Affiliation (based on the past Project Information) *help	2022: 帝京大学, 医学部, 教授 2018 – 2020: 帝京大学, 医学部, 教授 2013 – 2017: 帝京大学, 医学部, 准教授 2011 – 2012: 帝京大学, 医学部, 講師 2007 – 2008: Tokyo Medical and Dental University, 難治疾患研究所, 助教 2000 – 2006: Tokyo Med.& Dent.Univ., Med.Res.Inst., Research Associate, 難治疾患研究所, 助手
Review Section/Research Field	Principal Investigator Circulatory organs internal medicine / General medical chemistry / Basic Section 59040:Nutrition science and health science-related / Circulatory organs internal medicine Except Principal Investigator Biological Sciences / 病態科学系歯学(含放射線系歯学) / Circulatory organs internal medicine
Keywords	Principal Investigator Skp2 / 心筋細胞 / サイクリンD1 / 老化 / 細胞老化 / 糖質コルチコイド / 増殖 / 細胞増殖 / p27 / cardiomyocyte … More Except Principal Investigator TGFβ / 細胞増殖 / クロマチン構造 / 細胞死 / ATF3 / 抗がん剤作用 / 口腔癌 / 転写仲介因子 / p300遺伝子 / 癌抑制遺伝子 / ヒストンアセチル化酵素 / ブロモドメイン / p300 / oral cancer / transcriptional coactivator / tumor suppressor gene / 心筋再分裂 / 終末分化 / 再生 / サイクリンD / p27 / E3リガーゼ / ヒト心筋 / 心筋症 / サイクリンD1 / Skp2 / 心筋再分裂誘導 / 心不全モデル / ストレス応答遺伝子ATF3 / Alternate promoter / 紫外線誘導DNA傷害 / DNA傷害 / 発がん / がん抑制 / 細胞運命 / 転写制御 / c-myc標的 / スプライシング / 細胞生存阻害 / 新規プロモーター / Ras / atf3 floxed mouse / 転写抑制因子 / スプライス制御 / 遺伝情報伝達 / 網羅的標的遺伝子検索 / bromodomain / histone acetyltransferase / cell growth / クロマチン構造変換 / E2FBP1 / DRIL1 / 核マトリクス / ヒストアセチル化酵素 / chromatin remodeling / E2FBP 1 / DRIL 1 / nuclear matrix / cell prolorferaction Less

副腎の老化の制御による個体老化のコントロールと健康長寿を目指す研究Principal Investigator
- Principal Investigator
  
  安達三美
- Project Period (FY)
  2022 – 2024
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Review Section
  
  Basic Section 59040:Nutrition science and health science-related
- Research Institution
  Teikyo University
糖質コルチコイド制御による、老化のコントロールを目指す研究Principal Investigator
- Principal Investigator
  
  安達三美
- Project Period (FY)
  2019 – 2021
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Review Section
  
  Basic Section 59040:Nutrition science and health science-related
- Research Institution
  Teikyo University
Analysis of age-associated change of glucocorticoid productionPrincipal Investigator
- Principal Investigator
  
  Adachi Mimi
- Project Period (FY)
  2015 – 2018
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Research Field
  
  General medical chemistry
- Research Institution
  Teikyo University
Analysis of chromatin remodeling in cellular senescence and organismal agingPrincipal Investigator
- Principal Investigator
  
  ADACHI Mimi
- Project Period (FY)
  2011 – 2014
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Research Field
  
  General medical chemistry
- Research Institution
  Teikyo University
細胞周期制御因子による心筋再生療法の開発を目指した研究Principal Investigator
- Principal Investigator
  
  ADATI Mimi
- Project Period (FY)
  2007 – 2008
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Research Field
  
  Circulatory organs internal medicine
- Research Institution
  Tokyo Medical and Dental University
c-Myc標的遺伝子ATF3の細胞増殖と発がんに関する研究
- Principal Investigator
  
  北嶋繁孝
- Project Period (FY)
  2006 – 2007
- Research Category
  
  Grant-in-Aid for Scientific Research on Priority Areas
- Review Section
  
  Biological Sciences
- Research Institution
  Tokyo Medical and Dental University
bZip型転写抑制因子ATF3の細胞増殖と細胞死デコードシステムの解析
- Principal Investigator
  
  北嶋繁孝
- Project Period (FY)
  2006 – 2007
- Research Category
  
  Grant-in-Aid for Scientific Research on Priority Areas
- Review Section
  
  Biological Sciences
- Research Institution
  Tokyo Medical and Dental University
サイクリンD1の心筋特異的核内発現によるヒト心筋細胞再生法の開発
- Principal Investigator
  
  北嶋繁孝
- Project Period (FY)
  2005 – 2006
- Research Category
  
  Grant-in-Aid for Exploratory Research
- Research Field
  
  Circulatory organs internal medicine
- Research Institution
  Tokyo Medical and Dental University
Study of molecular mechanism of cardiomyocyte cell cycle and heart regenerationPrincipal Investigator
- Principal Investigator
  
  ADACHI Mimi
- Project Period (FY)
  2005 – 2006
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Research Field
  
  Circulatory organs internal medicine
- Research Institution
  Tokyo Medical and Dental University
Study of cell cycle mechanism for heart regenerationPrincipal Investigator
- Principal Investigator
  
  ADACHI Mimi
- Project Period (FY)
  2003 – 2004
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Research Field
  
  Circulatory organs internal medicine
- Research Institution
  Tokyo Medical and Dental University
心筋細胞における細胞周期;心筋細胞の再生を目指してPrincipal Investigator
- Principal Investigator
  
  安達三美
- Project Period (FY)
  2001 – 2002
- Research Category
  
  Grant-in-Aid for Young Scientists (B)
- Research Field
  
  Circulatory organs internal medicine
- Research Institution
  Tokyo Medical and Dental University
Alternations of Transcriptional Regulation in Oral Cancers and Analysis of Tumor Suppressive functions of p300 Transcriptional Co-activator
- Principal Investigator
  
  IKEDA Masa-aki
- Project Period (FY)
  2001 – 2003
- Research Category
  
  Grant-in-Aid for Scientific Research (B)
- Research Field
  
  病態科学系歯学(含放射線系歯学)
- Research Institution
  Tokyo Medical and Dental University
Alternations of the Transcriptional Co-activator p300 in Oral Cancers and Its Novel Role in Tumor Suppression
- Principal Investigator
  
  IKEDA Masa-aki
- Project Period (FY)
  1998 – 2000
- Research Category
  
  Grant-in-Aid for Scientific Research (B).
- Research Field
  
  病態科学系歯学(含放射線系歯学)
- Research Institution
  Tokyo Medical and Dental University

[Book] 個体でみられる細胞老化「実験医学2013年12月増刊号　老化・寿命研究の最前線」2013
- Author(s)
  安達（玉盛）三美
- Total Pages
  8
- Publisher
  羊土社
- Data Source
  KAKENHI-PROJECT-23590346
[Book] Topics心筋細胞の再分裂誘導は可能か「心筋症を識る, 診る, 治す」2007
- Author(s)
  安達三美
- Publisher
  文光堂
- Data Source
  KAKENHI-PROJECT-19590806
[Book] 心筋症を識る・診る・治す2007
- Author(s)
  安達三美
- Total Pages
  391
- Publisher
  文光堂
- Data Source
  KAKENHI-PROJECT-19590806
[Book] 発生における細胞増殖制御2004
- Author(s)
  池田正明, 安達三美
- Publisher
  シュプリンガー・フェアラーク東京
- Data Source
  KAKENHI-PROJECT-15590728
[Book] 心筋の増殖停止機構「発生における細胞増殖制御」(竹内隆, 岸本健夫/編)2004
- Author(s)
  池田正明, 安達三美
- Publisher
  シュプリンガー・フェアラーク東京
- Description
  「研究成果報告書概要(和文)」より
- Data Source
  KAKENHI-PROJECT-15590728
[Journal Article] 25(OH)D3 stimulates the expression of vitamin D target genes in renal tubular cells when Cyp27b1 is abrogated2020
- Author(s)
  Kikuyama T, Susa T, Tamamori-Adachi M, Iizuka M, Akimoto M, Okinaga H, Fujigaki Y, Uchida S, Shibata S, Okazaki T.
- Journal Title
  
  J Steroid Biochem Mol Biol.
  
  Volume: 199 Pages: 105593-105593
- DOI
  10.1016/j.jsbmb.2020.105593
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-19K09699, KAKENHI-PROJECT-19K11651, KAKENHI-PROJECT-19H03678, KAKENHI-PROJECT-17K09891, KAKENHI-PROJECT-15H05788, KAKENHI-PROJECT-19K22643
[Journal Article] Without 1α-hydroxylation, the gene expression profile of 25(OH)D3 treatment overlaps deeply with that of 1,25(OH)2D3 in prostate cancer cells.2018
- Author(s)
  Susa T,Tamamori-Adachi M., et., al.
- Journal Title
  
  Sci Rep
  
  Volume: 8 Pages: 9024-9024
- DOI
  10.1038/s41598-018-27441-x
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-15K08286, KAKENHI-PROJECT-16K20163
[Journal Article] DNA damage response induced by Etoposide promotes steroidogenesis via Gadd45A in cultured adrenal cells.2018
- Author(s)
  Tamamori-Adachi M., et., al.
- Journal Title
  
  Scientific Reports
  
  Volume: 8 Pages: 9636-9648
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-15K08286
[Journal Article] Not Only the Specific Mutant, But Also the Wild-Type Androgen Receptor, Mediates Transcription via 17β-Estradiol in Sex Hormone-Sensitive Cultured Cancer Cells2015
- Author(s)
  Susa T, Tamamori-Adachi M, et. al.
- Journal Title
  
  J Cell Physiol.
  
  Volume: 230 Pages: 1594-1606
- DOI
  10.1002/jcp.24906
- Peer Reviewed / Acknowledgement Compliant / Open Access
- Data Source
  KAKENHI-PROJECT-23590346, KAKENHI-PROJECT-24591372, KAKENHI-PROJECT-25870750, KAKENHI-PROJECT-15K08286
[Journal Article] Histone acetyltransferase Hbo1 destabilizes estrogen receptor α by ubiquitination and modulates proliferation of breast cancers.2014
- Author(s)
  Iizuka M, Tamamori-Adachi M, et. al.
- Journal Title
  
  Cancer Sci.
  
  Volume: 104 Pages: 1647-1655
- DOI
  10.1111/cas.12303
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-23590346, KAKENHI-PROJECT-24591372, KAKENHI-PROJECT-25870750
[Journal Article] Marked cortisol production by intracrine ACTH in GIP-treated cultured adrenal cells in which the GIP receptor was exogenouly introduced.2014
- Author(s)
  Fujii H, Tamamori-Adachi M, et. al.
- Journal Title
  
  PLoS ONE
  
  Volume: 9
- Peer Reviewed / Acknowledgement Compliant / Open Access
- Data Source
  KAKENHI-PROJECT-23590346
[Journal Article] Primary polydipsia, but not accumulated ceramide, causes lethal renal damage in saposin D-deficient mice.2012
- Author(s)
  Hisaki H, Tamamori-Adachi M, et. al.
- Journal Title
  
  Am. J. Physiol. Renal Physiol.
  
  Volume: 303 Pages: 1049-1059
- DOI
  10.1152/ajprenal.00047.2012
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-23590346, KAKENHI-PROJECT-24590285
[Journal Article] Nagative regulation of parathyroid hormine-related protein expression by steroid hormones.2011
- Author(s)
  Kajitani T, Tamamori-Adachi M, et. al.
- Journal Title
  
  Biochem. Biophys. Res. Commun.
  
  Volume: 407 Pages: 472-8
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-23590346
[Journal Article] Systems analysis of ATF3 in stress response and cancer reveals opposing effects on pro-apoptotic genes in p53 pathway.2011
- Author(s)
  Tanaka Y, Tamamori-Adachi M, et. al.
- Journal Title
  
  PLoS ONE.
  
  Volume: 6
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-23590346
[Journal Article] Age-associated increase in heterochromatic marks in murine and primate tissues.2011
- Author(s)
  Kreiling JA, Tamamori-Adachi M, et. al.
- Journal Title
  
  Aging Cell
  
  Volume: 10 Pages: 292-304
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-23590346
[Journal Article] Degradation of p21Cip1 through APC/Cdc20 mediated ubiquitylation is inhibited by cyclin dependent kinase 2 in cardiomyocytes.2011
- Author(s)
  Yamada K, Tamamori-Adachi M, et. al.
- Journal Title
  
  J. Biol. Chem.
  
  Volume: 296 Pages: 44057-66
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-23590346
[Journal Article] Nuclear protein accumulation in cellular senescence and organismal aging revealed with a novel single-cell resolution fluorescence microscopy assay.2011
- Author(s)
  De Cecco M, Tamamori-Adachi M, et. al.
- Journal Title
  
  Aging (Albany NY)
  
  Volume: 10 Pages: 955-67
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-23590346
[Journal Article] Skp2 promotes adipocyte differentiation via a p27Kip1-independent mechanism in primary mouse embryonic fibroblasts2009
- Author(s)
  Okada M, Sakai T, Nakamura T, Tamamori-Adachi M, Kitajima S, Matsuki Y, WatanabeE, Hiramatsu R, Sakaue H, Kasuga M
- Journal Title
  
  Biochem.Biophys.Res.Commun 379
  
  Pages: 249-254
- Data Source
  KAKENHI-PROJECT-19590806
[Journal Article] Differential usage of alternate promoters of the human stress response gene ATF3 in stress response and cancer cells2009
- Author(s)
  Miyazaki K, Inoue S, Yamada K, Watanabe M, Liu Q, Watanabe T, Tamamori-Adachi M, Tanaka Y, Kitajima S
- Journal Title
  
  Nucleic Acids Res 37
  
  Pages: 1438-51
- Data Source
  KAKENHI-PROJECT-19590806
[Journal Article] Tetraspanin TM4SF5 mediates epithelial-mesenchymal transition leading to loss of contact inhibition2008
- Author(s)
  Lee SA, Lee SY, Cho IH, Oh MA, Kang ES, Kim YB, Seo WD, Choi S, Nam JO, Tamamori-Adachi M, Kitajima S, Ye SK, Kim S, Hwang YJ, Kim IS, Park KH, Lee JW
- Journal Title
  
  J.Clin.Invest 18
  
  Pages: 1354-1366
- Data Source
  KAKENHI-PROJECT-19590806
[Journal Article] PDK1 regulates cell proliferation and cell cycle progression through control of cyclin D1 and p27Kip1 expression2008
- Author(s)
  Nakayama K, Sakaue H, Nishizawa A, Matsuki Y, Gomi H, Watanabe E, Hiramatsu R, Tamamori-adachi M, Kitajima S, Noda T, Ogawa W, Kasuga M
- Journal Title
  
  J.Biol.Chem 283
  
  Pages: 17702-17711
- Data Source
  KAKENHI-PROJECT-19590806
[Journal Article] Differential regulation of cyclin D1 and D2 in protecting against cardiomyocyte proliferation2008
- Author(s)
  Tamamori-Adachi M, Goto I, Yamada K, Kitajima S
- Journal Title
  
  Cell cycle 7
  
  Pages: 3768-3774
- Data Source
  KAKENHI-PROJECT-19590806
[Journal Article] Distinct roles of GSK 3a and GSK 3b phosphorylation in the heart under pressure overload.2008
- Author(s)
  Matsuda T, Tamamori-Adachi M, et. al.
- Journal Title
  
  Proc. Natl. Acad. Sci. USA 105
  
  Pages: 20900-20905
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-19590806
[Journal Article] Differential regulation of cyclin D1 and D2 in protecting against cardiomyocyte proliferation.2008
- Author(s)
  Tamamori-Adachi M, et. al.
- Journal Title
  
  Cell cycle 7
  
  Pages: 3768-3774
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-19590806
[Journal Article] Cardiomyocyte proliferation and protection against post-myocardial infarction heart failure by cyclin D1 and Skp2 ubiquitin ligase2008
- Author(s)
  Tamamori-Adachi M, Takagi H, Hashimoto K, Goto K, Hidaka T, Koshimizu U, Yamada K, Goto I, Maejima Y, Isobe M, Nakayama K.I, Inomata N, Kitajimas
- Journal Title
  
  Cardiovasc.Res 80
  
  Pages: 181-191
- Data Source
  KAKENHI-PROJECT-19590806
[Journal Article] Distinct roles of GSK 3a and GSK 3b phosphorylation in the heart under pressure overload2008
- Author(s)
  Matsuda T, Zhai P, Maejima Y, Hong C, Gao S, Tian B, Goto K, Takagi H, Tamamori-Adachi M, Kitajima S, Sadoshima J
- Journal Title
  
  Proc.Natl.Acad.Sci.USA 105
  
  Pages: 20900-20905
- Data Source
  KAKENHI-PROJECT-19590806
[Journal Article] Cardiomyocyte proliferation and protection against post-myocardial infarction heart failure by cyclin D1 and Skp2 ubiquitin ligase.2008
- Author(s)
  Tamamori-Adachi M, et. al.
- Journal Title
  
  Cardiovasc. Res. 80
  
  Pages: 181-191
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-19590806
[Journal Article] Induction of apoptosis and cellular senescence in mice lacking transcription elongation factor, Elongin A.2007
- Author(s)
  Miyata Y, Tamamori-Adachi M, et al.
- Journal Title
  
  Cell Death and differentiation 14
  
  Pages: 716-726
- Description
  「研究成果報告書概要(和文)」より
- Data Source
  KAKENHI-PROJECT-17590712
[Journal Article] Induction of apoptosis and cellular senescence in mice lacking transcription elongation factor, Elongin A.2007
- Author(s)
  Miyata Y, Yasukawa T, Fukuda M, Takeuchi T, Yamazak K, Sakumi K, Tamamori-Adachi M, Ohnishi Y, Ohtsuki Y, Nakabeppu Y, Kiatjima S, Aso T
- Journal Title
  
  Cell Death and Differentiation 14
  
  Pages: 716-726
- Description
  「研究成果報告書概要(欧文)」より
- Data Source
  KAKENHI-PROJECT-17590712
[Journal Article] Induction of apoptosis and cellular senescence in mice lacking transcription elongation factor, Elongin A2007
- Author(s)
  Miyata Y, Tamamori-Adachi M, et. Al.
- Journal Title
  
  Cell Death and differentiation 14
  
  Pages: 716-726
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-19590806
[Journal Article] Induction of apoptosis and cellular senescence in mice lacking transcription elongation factor, Elongin A2007
- Author(s)
  Miyata Y, Yasukawa T, Fukuda M, Takeuchi T, Yamazaki K, Sakumi K, Tamamori-Adachi M, Ohnishi Y, Ohtsuki Y, Nakabeppu Y, Kitajima S and Aso T
- Journal Title
  
  Cell Death and differentiation 14
  
  Pages: 716-726
- Data Source
  KAKENHI-PROJECT-19590806
[Journal Article] HMG-CoA reductase inhibitor fluvastatin prevents angiotensin II-induced cardiac hypertrophy via Rho kinase and inhibition of cyclin D1.2006
- Author(s)
  Morikawa-Futamatsu K, Tamamori-Adachi M, et al.
- Journal Title
  
  Life Sci. 79
  
  Pages: 1380-1390
- Description
  「研究成果報告書概要(和文)」より
- Data Source
  KAKENHI-PROJECT-17590712
[Journal Article] A splice variant of stress response gene ATF3 counteracts NF-κB-dependent anti-apoptosis through inhibiting recruitment of CBP/p300 coactivator.2006
- Author(s)
  Bayin H, Tamamori-Adachi M, Yang L, Tamura K, Morioka M, Tanaka T, Kitajima S
- Journal Title
  
  J.Biol.Chem. 281
  
  Pages: 1620-1629
- Description
  「研究成果報告書概要(欧文)」より
- Data Source
  KAKENHI-PROJECT-17590712
[Journal Article] HMG-CoA reductase inhibitor fluvastatin prevents angiotensin II-induced cardiac hypertrophy via Rho kinase and inhibition of cyclin D1.2006
- Author(s)
  Morikawa-Futamatsu K, Adachi S, Maejima Y, Tamamori-Adach M, Suzuki J, Kitajima S, Ito H, Isobe M
- Journal Title
  
  Life Sci. 79
  
  Pages: 1380-1390
- Description
  「研究成果報告書概要(欧文)」より
- Data Source
  KAKENHI-PROJECT-17590712
[Journal Article] A splice variant of stress response gene ATF3 counteracts NF-κβ-dependent anti-apoptosis through inhibiting recruitment of CBP/p300 coactivator.2006
- Author(s)
  Bayin H., Tamamori-Adachi M., et al.
- Journal Title
  
  J.Biol.Chem. 281
  
  Pages: 1620-1629
- Data Source
  KAKENHI-PROJECT-17590712
[Journal Article] A splice variant of stress response gene ATF3 counteracts NF-κB-dependent anti-apoptosis through inhibiting recruitment of CBP/p300 coactivator.2006
- Author(s)
  Bayin H, Tamamori-Adachi M, et al.
- Journal Title
  
  J. Biol. Chem. 281
  
  Pages: 1620-1629
- Description
  「研究成果報告書概要(和文)」より
- Data Source
  KAKENHI-PROJECT-17590712
[Journal Article] Stress response gene ATF3 is a target of c-myc is serum-induced cell proliferation.2005
- Author(s)
  Tamura K, Bayin H, Adachi S, Guney I, Kawauchi J, Morioka M, Tamamori-Adachi M, Tanaka Y, Nakabeppu Y, Sunamori M, Sedivy JM, Kitajima S
- Journal Title
  
  EMBO 24
  
  Pages: 2590-2601
- Description
  「研究成果報告書概要(欧文)」より
- Data Source
  KAKENHI-PROJECT-17590712
[Journal Article] Cyclin A-associated kinase activity is needed for paclitaxel sensitivity.2005
- Author(s)
  Takahashi T., Yamasaki F., Sudo T., Itamochi H., Adachi S., Tamamochi-Adachi M., Ueno NT
- Journal Title
  
  Mol.Cancer Thar. 4
  
  Pages: 1039-1046
- Description
  「研究成果報告書概要(欧文)」より
- Data Source
  KAKENHI-PROJECT-17590712
[Journal Article] Cyclin A-associated kinase activity is needed for paclitaxel sensitivity.2005
- Author(s)
  Takahashi T., Tamamori-Adachi M., et al.
- Journal Title
  
  Mol. Cancer Thar. 4
  
  Pages: 1039-1046
- Description
  「研究成果報告書概要(和文)」より
- Data Source
  KAKENHI-PROJECT-17590712
[Journal Article] Stress response gene ATF3 is a target of c-myc in serum-induced cell proliferation.2005
- Author(s)
  Tamura K., Tamamori-Adachi M., et al.
- Journal Title
  
  EMBO 24
  
  Pages: 2590-2601
- Description
  「研究成果報告書概要(和文)」より
- Data Source
  KAKENHI-PROJECT-17590712
[Journal Article] Direct modulation of rheumatoid inflammatory mediator expression in rerinoblastoma protein-dependent and -independent pathways cyclin - dependent kinase 4/62005
- Author(s)
  Nonomura Y, Tamamori-Adachi M, et al.
- Journal Title
  
  Arthritis Rheum. 54
  
  Pages: 2074-2083
- Description
  「研究成果報告書概要(和文)」より
- Data Source
  KAKENHI-PROJECT-17590712
[Journal Article] Down-regulation of p27^<kipl> promotes cell proliferation of rat neonatal cardiomyocytes induced by nuclear expression of cyclin D1 and CDK4:Evidence for impaired Skp2-dependent degradetion of p27 in terminal differentiation.2004
- Author(s)
  Tamamori-Adachi M, et al.
- Journal Title
  
  J.Biol.Chem. 279
  
  Pages: 50429-50436
- Data Source
  KAKENHI-PROJECT-15590728
[Journal Article] Down-regulation of p27^<Kip1> promotes cell proliferation of rat neonatal cariomyocytes induced by nuclear expression of cyclin D1 and CDK4 : Evidence for impaired Skp2-dependent degradation of p27 in terminal differentiation.2004
- Author(s)
  Tamamori-Adachi M.et al.
- Journal Title
  
  V.Biol.Chem. 279
  
  Pages: 50429-50436
- Description
  「研究成果報告書概要(和文)」より
- Data Source
  KAKENHI-PROJECT-15590728
[Journal Article] Down-regulation of p27^<Kip1> promotes cell proliferation of rat neonatal cardiomyocytes induced by nuclear expression of cyclinD1 and CDK4 : Evidence for impaired Skp2-dependent degradation of p27 in terminal differentiation.2004
- Author(s)
  Tamamori-Adachi M., Hayashida K, Nobori K, Omizu C, Yamada K, Sakamoto N, Kamura T, Fukuda K, Ogawa S, Nakayama KI, Kitajima S
- Journal Title
  
  J.Biol.Chem. 279
  
  Pages: 50429-50436
- Description
  「研究成果報告書概要(欧文)」より
- Data Source
  KAKENHI-PROJECT-15590728
[Journal Article] E2FBP1/DRIL1, an AT-rich interaction domain-family transcription factor, is regulated by p53.2003
- Author(s)
  Ma K, Tamamori-Adachi M. et al.
- Journal Title
  
  Mol.Cans.Res. 1
  
  Pages: 438-444
- Description
  「研究成果報告書概要(和文)」より
- Data Source
  KAKENHI-PROJECT-15590728
[Journal Article] Nitiric oxide inhibits ischemia/reperfusion-induced myocardial apoptosis by modulating cyclin A-associated kinase activity.2003
- Author(s)
  Maejima Y., Tamamori-Adachi M.et al.
- Journal Title
  
  Cardiovasc.Res. 59
  
  Pages: 308-320
- Description
  「研究成果報告書概要(和文)」より
- Data Source
  KAKENHI-PROJECT-15590728
[Journal Article] Role of cyclin D1 cytoplasmic sequestration in the survival of postmitotic neurons.2003
- Author(s)
  Sumrejkanchanakij P, Tamamori-Adachi M., Matsunaga Y., Eto K., Ikeda M
- Journal Title
  
  Oncogene 22
  
  Pages: 8723-8730
- Description
  「研究成果報告書概要(欧文)」より
- Data Source
  KAKENHI-PROJECT-15590728
[Journal Article] Role of cyclin Dl cytoplasmic sequestration in the survival of postmitotic neurons.2003
- Author(s)
  Sumrejkanchanakij P, Tamamori-Adachi M. et al.
- Journal Title
  
  Oncogene 22
  
  Pages: 8723-8730
- Description
  「研究成果報告書概要(和文)」より
- Data Source
  KAKENHI-PROJECT-15590728
[Journal Article] Nitiric oxide inhibits ischemia/reperfusion-induced myocardial apoptosis by modulating cyclin A-associated kinase activity.2003
- Author(s)
  Maejima Y., Adachi S., Ito H., Nobori K., Tamamori-Adachi M., Isobe M
- Journal Title
  
  Cardiovasc.Res. 59
  
  Pages: 308-320
- Description
  「研究成果報告書概要(欧文)」より
- Data Source
  KAKENHI-PROJECT-15590728
[Journal Article] E2FBP1/DRIL1, an AT rich interaction domain-family transcription factor, is regulated by p53.2003
- Author(s)
  Ma K., Araki K., Ichwan SJA., Suganuma T., Tamamori-Adachi M., Ikeda M
- Journal Title
  
  Mol.Cans.Res. 1
  
  Pages: 438-444
- Description
  「研究成果報告書概要(欧文)」より
- Data Source
  KAKENHI-PROJECT-15590728
[Presentation] HOXC遺伝子を軸としたビタミンD3によるヒト前立腺癌の抗増殖作用の分子機序2020
- Author(s)
  諏佐崇生、安達（玉盛）三美等
- Organizer
  第93回日本内分泌学会学術総会
- Data Source
  KAKENHI-PROJECT-19K11651
[Presentation] Saposin D-KOマウスの飲水行動とprogranulin2020
- Author(s)
  久樹晴美、安達（玉盛）三美等
- Organizer
  第93回日本生化学会大会
- Data Source
  KAKENHI-PROJECT-19K11651
[Presentation] HOXC遺伝子を軸としたビタミンD3によるヒト前立腺癌の抗増殖作用の分子機序2020
- Author(s)
  諏佐崇生、安達（玉盛）三美等
- Organizer
  第43回日本分子生物学会年会
- Data Source
  KAKENHI-PROJECT-19K11651
[Presentation] 加齢による糖質コルチコイド分泌撹乱のメカニズムの解析2020
- Author(s)
  安達（玉盛）三美等
- Organizer
  第93回日本生化学会大会
- Data Source
  KAKENHI-PROJECT-19K11651
[Presentation] 異所性副甲状腺ホルモン産生悪性線維性組織球腫で検出された新規lncRNAの解析2020
- Author(s)
  秋元美穂、安達（玉盛）三美等
- Organizer
  第43回日本分子生物学会年会
- Data Source
  KAKENHI-PROJECT-19K11651
[Presentation] The change of steroidogenesis with aging in mouse adrenal gland2020
- Author(s)
  奥平准之、安達（玉盛）三美等
- Organizer
  第43回日本分子生物学会年会
- Data Source
  KAKENHI-PROJECT-19K11651
[Presentation] saposin D欠損マウスの過剰飲水行動を制御するタンパク質2019
- Author(s)
  久樹　晴美、安達（玉盛）三美 et al.
- Organizer
  第92回日本生化学会
- Data Source
  KAKENHI-PROJECT-19K11651
[Presentation] 時計関連遺伝子群が、糖質コルチコイド分泌撹乱に伴う諸組織の老化に緊密に関与する．2019
- Author(s)
  安達（玉盛）三美 et al.
- Organizer
  第42回日本分子生物学会年会
- Data Source
  KAKENHI-PROJECT-19K11651
[Presentation] 5(OH)D3は腎細胞においてビタミンD3活性を発揮する．2019
- Author(s)
  諏佐　崇生、安達（玉盛）三美 et al.
- Organizer
  第92回日本内分泌学会学術総会
- Data Source
  KAKENHI-PROJECT-19K11651
[Presentation] ヒト前立腺癌LNCaP細胞におけるDHTとビタミンD3によるHOXC遺伝子群の拮抗的な転写制御機構2019
- Author(s)
  諏佐　崇生、安達（玉盛）三美 et al.
- Organizer
  第42回日本分子生物学会年会
- Data Source
  KAKENHI-PROJECT-19K11651
[Presentation] 25(OH)D3は腎細胞においてビタミンD3活性を発揮する．2019
- Author(s)
  菊山　崇浩、安達（玉盛）三美 et al.
- Organizer
  第62回日本腎臓学会学術総会
- Data Source
  KAKENHI-PROJECT-19K11651
[Presentation] saposin D欠損マウスの過剰飲水行動と口渇中枢を制御するタンパク質2018
- Author(s)
  久樹晴美、安達（玉盛）三美、et. al.
- Organizer
  第91回日本生化学会大会
- Data Source
  KAKENHI-PROJECT-15K08286
[Presentation] 腎臓遠位尿細管細胞mpkDCT細胞を用いたCyp27b1ノックアウト細胞の樹立と25(OH)D3の生理活性の評価2018
- Author(s)
  菊山崇浩、諏佐崇生、安達（玉盛）三美、et. al.
- Organizer
  第41回日本分子生物学会年会
- Data Source
  KAKENHI-PROJECT-15K08286
[Presentation] 加齢に伴い、HPA軸によるネガティブフィードバック反応系が減弱し、糖質コルチコイド合成が促進される2018
- Author(s)
  安達（玉盛）三美、et. al.
- Organizer
  第41回日本分子生物学会年会
- Data Source
  KAKENHI-PROJECT-15K08286
[Presentation] ヒト前立腺癌LNCaP細胞における25(OH)D3のビタミンD3活性の評価．第91 回日本内分泌学会学術総会2018
- Author(s)
  諏佐崇生、安達三美、et. al.
- Organizer
  第91 回日本内分泌学会学術総会
- Data Source
  KAKENHI-PROJECT-15K08286
[Presentation] Transcriptional Repression of the Metallothionein Gene Family by 1,25(OH)2D3 Is Mediated by Androgen Receptor in Prostate Cancer LNCaP Cells.2017
- Author(s)
  諏佐　崇生、安達　三美 et al.
- Organizer
  ENDO2017 The Endocrine Society's 99 th Annual Meeting & Expo
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-15K08286
[Presentation] DNA damage response induces cell-autonomous steroidogenesis via GADD45a-p38MAPK in human adrenocortical tumor H295R cells2017
- Author(s)
  Mimi Tamamori-Adachi, et. al.
- Organizer
  The Endocrine Society's 99th Annual Meeting and Expo
- Place of Presentation
  Orange County Convention Center, Orlando, FL, USA
- Year and Date
  2017-04-01
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-15K08286
[Presentation] DNA損傷刺激により、副腎皮質腫瘍細胞株（H295R）においてコルチゾール分泌能が増大する2017
- Author(s)
  安達　三美 et al.
- Organizer
  2017年度生命科学系学会合同年次大会（Conbio2017）
- Data Source
  KAKENHI-PROJECT-15K08286
[Presentation] ヒト前立腺癌LNCaP細胞において25(OH)D3は1,25(OH)2D3の標的遺伝子と類似した遺伝子群を制御する2017
- Author(s)
  諏佐　崇生、安達　三美 et al.
- Organizer
  2017年度生命科学系学会合同年次大会（Conbio2017）
- Data Source
  KAKENHI-PROJECT-15K08286
[Presentation] DNA damage response induces cell-autonomous steroidogenesis via GADD45a-p38MAPK in human adrenocortical tumor H295R cells2017
- Author(s)
  安達　三美 et al.
- Organizer
  ENDO2017 The Endocrine Society's 99 th Annual Meeting & Expo
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-15K08286
[Presentation] CYP24A1 Overexpression, Scarcity of Calcium-Sensing Receptor and Cell-specific Long Non-Coding RNA Characterize Gene Expression Pattern of Ectopic PTH-Producing Tumor in the Retroperitoneum.2017
- Author(s)
  岡崎　具樹、安達　三美 et al.
- Organizer
  ENDO2017 The Endocrine Society's 99 th Annual Meeting & Expo
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-15K08286
[Presentation] DNA損傷刺激により、p38MAPKの活性を介して、副腎皮質腫瘍細胞株(H295R)において自律的にコルチゾール分泌が促進する。2016
- Author(s)
  安達　三美　他
- Organizer
  第39回日本分子生物学会年会
- Place of Presentation
  神奈川県横浜市パシフィコ横浜
- Year and Date
  2016-11-30
- Data Source
  KAKENHI-PROJECT-15K08286
[Presentation] Genotoxic or Oxidative Stress Induces Cell-Autonomous Steroidogenesis in Human Adrenocortical Tumor H295R Cells2016
- Author(s)
  Mimi Tamamori-Adachi, et. al.
- Organizer
  ENDO2016 (The Endocrine Society's 98th Annual Meeting & EXPO)
- Place of Presentation
  Boston Convention and Exhibition Center, Boston, MA, USA
- Year and Date
  2016-04-01
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-15K08286
[Presentation] ヒストンアセチルトランスフェラーゼHbo1は、エストロゲン受容体に対するE3リガーゼ活性を持つ2016
- Author(s)
  飯塚　真由、安達　三美他
- Organizer
  第39回日本分子生物学会年会
- Place of Presentation
  神奈川県横浜市パシフィコ横浜
- Year and Date
  2016-11-30
- Data Source
  KAKENHI-PROJECT-15K08286
[Presentation] ヒト前立腺癌LNCaP細胞におけるDHT-ARへのクロストークを介したビタミンD3によるMetallothionein遺伝子群の転写抑制機構の解析2016
- Author(s)
  諏佐　崇生、安達　三美他
- Organizer
  第39回日本分子生物学会年会
- Place of Presentation
  神奈川県横浜市パシフィコ横浜
- Year and Date
  2016-11-30
- Data Source
  KAKENHI-PROJECT-15K08286
[Presentation] Distinct Signaling Pathways of 1,25(OH)2D3 and 25(OH)2D3 via AR in Prostate Cancer2016
- Author(s)
  Takao Susa, Mimi Tamamori-Adachi, et. al.
- Organizer
  ENDO2016 (The Endocrine Society's 98th Annual Meeting & EXPO)
- Place of Presentation
  Boston Convention and Exhibition Center, Boston, MA, USA
- Year and Date
  2016-04-01
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-15K08286
[Presentation] ヒストンアセチルトランスフェラーゼHbo1による、エストロゲン受容体タンパク質の非定型的ユビキチン化2015
- Author(s)
  飯塚真由、安達（玉盛）三美他
- Organizer
  第38回日本分子生物学会年会
- Place of Presentation
  神戸ポートアイランド(兵庫県、神戸市）
- Year and Date
  2015-12-01
- Data Source
  KAKENHI-PROJECT-15K08286
[Presentation] 老化誘導ヒト副腎皮質腫瘍細胞株（H295R）におけるステロイドホルモン合成メカニズムの解析2015
- Author(s)
  安達（玉盛）三美他
- Organizer
  第38回日本分子生物学会年会
- Place of Presentation
  神戸ポートアイランド(兵庫県、神戸市）
- Year and Date
  2015-12-01
- Data Source
  KAKENHI-PROJECT-15K08286
[Presentation] ヒト前立腺癌LNCap細胞において、ビタミンD3とDHTがアンドロゲン受容体情報伝達系を共有する分子機構2015
- Author(s)
  諏佐　崇生、安達（玉盛）三美他
- Organizer
  第38回日本分子生物学会年会
- Place of Presentation
  神戸ポートアイランド(兵庫県、神戸市）
- Year and Date
  2015-12-01
- Data Source
  KAKENHI-PROJECT-15K08286
[Presentation] CDK2が心筋細胞におけるAPC/CCdc20ユビキチンリガーゼを介するp21のユビキチン化を抑制する。2011
- Author(s)
  安達（玉盛）三美
- Organizer
  第34回日本分子生物学会年会
- Place of Presentation
  パシフィコ横浜
- Data Source
  KAKENHI-PROJECT-23590346
[Presentation] 終末分化心筋細胞における細胞周期メカニズムの解析2008
- Author(s)
  安達三美, 他
- Organizer
  第31回分子生物学会
- Place of Presentation
  兵庫県神戸市神戸ポートアイランド
- Year and Date
  2008-12-10
- Data Source
  KAKENHI-PROJECT-19590806
[Presentation] 終末分化心筋細胞における細胞周期メカニズムの解析2008
- Author(s)
  安達(玉盛)三美、他
- Organizer
  第30回日本分子生物学年会
- Place of Presentation
  神戸
- Data Source
  KAKENHI-PROJECT-19590806
[Presentation] 心筋細胞ではAPC/CCdc20ユビキチンリガーゼを介するp21Cip1のユビキチン化がCDK2によって抑制される2008
- Author(s)
  山田一彦, 安達(玉盛)三美, 他
- Organizer
  第30回日本分子生物学年会
- Place of Presentation
  神戸
- Data Source
  KAKENHI-PROJECT-19590806
[Presentation] CTD phosphatase FCP1 の機能解析2007
- Author(s)
  渡辺雅司、安達(玉盛)三美, 他
- Organizer
  第29回日本分子生物学年会
- Place of Presentation
  横浜
- Data Source
  KAKENHI-PROJECT-19590806
[Presentation] CTD phosphatase FCP1の機能解析2007
- Author(s)
  渡辺雅司、小林真喜、安達三美、田中裕二郎、北嶋繁孝
- Organizer
  日本分子生物学会
- Place of Presentation
  横浜
- Year and Date
  2007-12-12
- Data Source
  KAKENHI-PROJECT-18012015
[Presentation] 終末分化心筋細胞における増殖および再増殖停止メカニズムの解析2007
- Author(s)
  安達三美, 他
- Organizer
  第30回分子生物学会年会
- Place of Presentation
  神奈川県横浜市パシフィコ横浜
- Year and Date
  2007-12-12
- Data Source
  KAKENHI-PROJECT-19590806
[Presentation] 終末分化心筋細胞における増殖および再増殖停止メカニズムの解析2007
- Author(s)
  安達(玉盛)三美, 他
- Organizer
  第29回日本分子生物学年会
- Place of Presentation
  横浜
- Data Source
  KAKENHI-PROJECT-19590806
[Presentation] サイクリンD1の核内発現によるラット心筋増殖誘導の解析2007
- Author(s)
  安達三美, ら
- Organizer
  日本分子生物学会
- Place of Presentation
  横浜
- Data Source
  KAKENHI-PROJECT-18055008
[Presentation] p21はCDK2と結合することによってユビキチン化を抑制し、終末分化心筋細胞の再増殖を停止させる2007
- Author(s)
  山田一彦、安達(玉盛)三美, 他
- Organizer
  第29回日本分子生物学年会
- Place of Presentation
  横浜
- Data Source
  KAKENHI-PROJECT-19590806
[Presentation] ストレス応答転写因子ATF3の選択的プロモーター制御とクロマチン構造2007
- Author(s)
  宮崎敬介、井上翔子、渡辺雅司、安達三美、田中裕二郎、北嶋繁孝
- Organizer
  日本分子生物学会
- Place of Presentation
  横浜
- Year and Date
  2007-12-12
- Data Source
  KAKENHI-PROJECT-18012015
[Presentation] PDK1はcyclin D1とp27Kip1の発現制御により細胞周期進行と細胞増殖能を誘導する2007
- Author(s)
  中村恭子、安達(玉盛)三美, 他
- Organizer
  第29回日本分子生物学年会
- Place of Presentation
  横浜
- Data Source
  KAKENHI-PROJECT-19590806
[Presentation] ストレス応答性転写因子ATF3の選択的プロモーター制御とクロマチン構造2007
- Author(s)
  宮崎敬介、安達(玉盛)三美, 他
- Organizer
  第29回日本分子生物学年会
- Place of Presentation
  横浜
- Data Source
  KAKENHI-PROJECT-19590806
[Presentation] Nuclear protein accumulation in cellular senescence and organismal aging revealed with a novel single-cell resolution fluorescence microscopy assay
- Author(s)
  安達　三美
- Organizer
  第35回日本分子生物学会年会
- Place of Presentation
  福岡県福岡市
- Data Source
  KAKENHI-PROJECT-23590346
[Presentation] ヒト培養細胞およびマウス組織における老化細胞のAldolase A発現の増加
- Author(s)
  安達（玉盛）三美　他
- Organizer
  第36回日本分子生物学会年会
- Place of Presentation
  兵庫県神戸市
- Data Source
  KAKENHI-PROJECT-23590346
[Presentation] GIPRを発現させたヒト副腎皮質腫瘍細胞株（H295R）におけるステロイドホルモン合成メカニズムの解析
- Author(s)
  安達（玉盛）三美等
- Organizer
  第37回日本分子生物学会
- Place of Presentation
  パシフィコ横浜
- Year and Date
  2014-11-25 – 2014-11-27
- Data Source
  KAKENHI-PROJECT-23590346
[Presentation] いくつかの男性／女性ホルモン感受性培養癌細胞では、17b-estradiolは、DHTと同様に、外来性に導入した非変異型ARの生理的アゴニストとして機能する
- Author(s)
  諏佐崇生、安達（玉盛）三美等
- Organizer
  第37回日本分子生物学会
- Place of Presentation
  パシフィコ横浜
- Year and Date
  2014-11-25 – 2014-11-27
- Data Source
  KAKENHI-PROJECT-23590346
[Presentation] ヒストンアセチルトランスフェラーゼHbo1によるエストロゲン受容体タンパク質のユビキチン化部位の同定
- Author(s)
  飯塚真由、安達（玉盛）三美等
- Organizer
  第37回日本分子生物学会
- Place of Presentation
  パシフィコ横浜
- Year and Date
  2014-11-25 – 2014-11-27
- Data Source
  KAKENHI-PROJECT-23590346

1. 北嶋繁孝 (30186241)

# of Collaborated Projects: 3 results

# of Collaborated Products: 2 results
2. IKEDA Masa-aki (20193211)

# of Collaborated Projects: 2 results

# of Collaborated Products: 0 results
3. IKEDA Yayoi (00202903)

# of Collaborated Projects: 2 results

# of Collaborated Products: 0 results
4. 砂盛誠 (90138280)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
5. 磯部光章 (80176263)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
6. 岡崎具樹 (60203973)

# of Collaborated Projects: 1 results

# of Collaborated Products: 4 results
7. MATSUDA Junko

# of Collaborated Projects: 0 results

# of Collaborated Products: 1 results
8. 諏佐崇生

# of Collaborated Projects: 0 results

# of Collaborated Products: 4 results
9. 柴田茂

# of Collaborated Projects: 0 results

# of Collaborated Products: 1 results
10. 秋元美穂

# of Collaborated Projects: 0 results

# of Collaborated Products: 1 results
11. 森典子

# of Collaborated Projects: 0 results

# of Collaborated Products: 1 results
12. 藤垣嘉秀

# of Collaborated Projects: 0 results

# of Collaborated Products: 1 results

ADACHI Mimi 安達 三美

安達 三美 アダチ ミミ

ADATI Mimi 安達 三美

玉盛 三美 タマモリ ミミ

Research Projects

Research Products

Co-Researchers

副腎の老化の制御による個体老化のコントロールと健康長寿を目指す研究Principal Investigator

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糖質コルチコイド制御による、老化のコントロールを目指す研究Principal Investigator

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Analysis of age-associated change of glucocorticoid productionPrincipal Investigator

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Analysis of chromatin remodeling in cellular senescence and organismal agingPrincipal Investigator

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細胞周期制御因子による心筋再生療法の開発を目指した研究Principal Investigator

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c-Myc標的遺伝子ATF3の細胞増殖と発がんに関する研究

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bZip型転写抑制因子ATF3の細胞増殖と細胞死デコードシステムの解析

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サイクリンD1の心筋特異的核内発現によるヒト心筋細胞再生法の開発

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Study of molecular mechanism of cardiomyocyte cell cycle and heart regenerationPrincipal Investigator

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Study of cell cycle mechanism for heart regenerationPrincipal Investigator

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心筋細胞における細胞周期;心筋細胞の再生を目指してPrincipal Investigator

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Alternations of Transcriptional Regulation in Oral Cancers and Analysis of Tumor Suppressive functions of p300 Transcriptional Co-activator

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Alternations of the Transcriptional Co-activator p300 in Oral Cancers and Its Novel Role in Tumor Suppression

ADACHI Mimi 安達三美

安達三美アダチミミ

ADATI Mimi 安達三美

玉盛三美タマモリミミ

[Book] 個体でみられる細胞老化「実験医学2013年12月増刊号　老化・寿命研究の最前線」2013

[Book] 心筋の増殖停止機構「発生における細胞増殖制御」(竹内隆, 岸本健夫/編)2004