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KOJIMA Kensuke  小島 研介

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KOJIMA KENSUKE  小島 研介

小島 研介  コジマ ケンスケ

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Researcher Number 10332793
Other IDs
Affiliation (Current) 2025: 高知大学, 教育研究部医療学系臨床医学部門, 教授
Affiliation (based on the past Project Information) *help 2019 – 2023: 高知大学, 教育研究部医療学系臨床医学部門, 教授
2014 – 2018: 佐賀大学, 医学部, 准教授
2002 – 2003: 愛媛大学, 医学部附属病院, 助手
Review Section/Research Field
Principal Investigator
Hematology / Basic Section 54010:Hematology and medical oncology-related / Hematology
Except Principal Investigator
Hematology
Keywords
Principal Investigator
p53 / 分子標的治療 / 造血器腫瘍 / 悪性リンパ腫 / 白血病 / 急性骨髄性白血病 / MYC / 細胞死 / シグナル伝達 / 耐性 … More / MCL-1 / 薬剤耐性 / BCL-2 / 造血微小環境 / MDM2 / 幹細胞 / 微小環境 / 診断 / 血球貧食症候群 / クローナリティ / 血球貪食症候群 / 悪性リンパ種 … More
Except Principal Investigator
フローサイトメトリー / 成人T細胞白血病・リンパ腫 / 癌 / 多段階発がん / メチル化 / ゲノム異常 / フローサイトメトリー法 / 分子標的治療 / エピジェネティック変化 / DNAメチル化 / HTLV-1 / 成人T細胞白血病 Less
  • Research Projects

    (5 results)
  • Research Products

    (81 results)
  • Co-Researchers

    (16 People)
  •  p53シグナルの機能的ヒエラルキー変化による悪性リンパ腫の分子標的治療耐性の解明Principal Investigator

    • Principal Investigator
      小島 研介
    • Project Period (FY)
      2021 – 2024
    • Research Category
      Grant-in-Aid for Scientific Research (C)
    • Review Section
      Basic Section 54010:Hematology and medical oncology-related
    • Research Institution
      Kochi University
  •  Induction of p53-dependent and -independent mitochondrial death based on the BCL-2 profile in hematological malignanciesPrincipal Investigator

    • Principal Investigator
      KOJIMA KENSUKE
    • Project Period (FY)
      2017 – 2020
    • Research Category
      Grant-in-Aid for Scientific Research (C)
    • Research Field
      Hematology
    • Research Institution
      Kochi University
      Saga University
  •  Epigenetic changes in the development of adult T cell leukemia

    • Principal Investigator
      Sueoka Eisaburo
    • Project Period (FY)
      2016 – 2018
    • Research Category
      Grant-in-Aid for Scientific Research (C)
    • Research Field
      Hematology
    • Research Institution
      Saga University
  •  Functional disruption of leukemia microenvironment by leukemia p53Principal Investigator

    • Principal Investigator
      KOJIMA KENSUKE
    • Project Period (FY)
      2014 – 2016
    • Research Category
      Grant-in-Aid for Scientific Research (C)
    • Research Field
      Hematology
    • Research Institution
      Saga University
  •  血球貧食症候群の発症に関わるリンパ球増殖のクローン解析Principal Investigator

    • Principal Investigator
      小島 研介
    • Project Period (FY)
      2002 – 2003
    • Research Category
      Grant-in-Aid for Young Scientists (B)
    • Research Field
      Hematology
    • Research Institution
      Ehime University

All 2023 2022 2021 2020 2019 2018 2017 2016 2015 2014 Other

All Journal Article Presentation Book

  • [Book] Targeted Therapy of Acute Myeloid Leukemia.2015

    • Author(s)
      Kojima K, Vassilev LT.
    • Total Pages
      16
    • Publisher
      Springer
    • Data Source
      KAKENHI-PROJECT-26461425
  • [Book] Targeted Therapy in Translational Cancer Research.2015

    • Author(s)
      Kojima K, Andreeff M.
    • Total Pages
      7
    • Publisher
      John Wiley & Sons
    • Data Source
      KAKENHI-PROJECT-26461425
  • [Journal Article] Psoas and Mediastinal Abscesses during Intravenous Tocilizumab Treatment in Multicentric Castleman Disease2023

    • Author(s)
      Togitani Kazuto、Ogasawara Fumiya、Arakawa Yu、Sugimura Natsuki、Miyazaki Ryohei、Kojima Kensuke
    • Journal Title

      Intern. Med.

      Volume: 62 Issue: 3 Pages: 449-452

    • DOI

      10.2169/internalmedicine.9519-22

    • ISSN
      0918-2918, 1349-7235
    • Year and Date
      2023-02-01
    • Language
      English
    • Peer Reviewed / Open Access
    • Data Source
      KAKENHI-PROJECT-21K08396
  • [Journal Article] COVID-19 Cluster in the Hematology/Respirology Ward of a University Hospital during the Seventh Wave of the SARS-CoV-2 Pandemic in Japan: A Descriptive Study2023

    • Author(s)
      Ogasawara Fumiya、Yoshida Shohei、Yamane Mayuka、Takamatsu Kazufumi、Arakawa Yu、Nishida Yoshie、Komatsu Megumi、Yokoyama Akihito、Yamagishi Yuka、Kojima Kensuke
    • Journal Title

      Intern. Med.

      Volume: 62 Issue: 9 Pages: 1265-1271

    • DOI

      10.2169/internalmedicine.1252-22

    • ISSN
      0918-2918, 1349-7235
    • Year and Date
      2023-05-01
    • Language
      English
    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-21K08396
  • [Journal Article] Unilateral lymphadenitis caused by community-associated methicillin-resistant Staphylococcus aureus ST834 strain2023

    • Author(s)
      Eda Hitomi、Arakawa Yu、Yoshida Takuma、Ogasawara Fumiya、Kojima Kensuke、Nakaminami Hidemasa、Yamagishi Yuka
    • Journal Title

      Journal of Infection and Chemotherapy

      Volume: S1341-321X Issue: 7 Pages: 00309-4

    • DOI

      10.1016/j.jiac.2023.12.005

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-21K08396
  • [Journal Article] Clinical utility of genomic profiling of AML using paraffin‐embedded bone marrow clots: HM‐SCREEN‐Japan 012023

    • Author(s)
      Hosono Naoko、Chi SungGi、Yamauchi Takahiro、Fukushima Kentaro、Shibayama Hirohiko、Katagiri Seiichiro et al.
    • Journal Title

      Cancer Science

      Volume: 114 Issue: 5 Pages: 2098-2108

    • DOI

      10.1111/cas.15746

    • Peer Reviewed / Open Access
    • Data Source
      KAKENHI-PROJECT-21K07200, KAKENHI-PROJECT-21K08396, KAKENHI-PROJECT-21K07239
  • [Journal Article] Targeting cis-regulatory elements of FOXO family is a novel therapeutic strategy for induction of leukemia cell differentiation2023

    • Author(s)
      Kurayoshi K, Takase Y, Ueno M, Ohta K, Fuse K, Ikeda S, Watanabe T, Nishida Y, Horike SI, Hosomichi K, Ishikawa Y, Tadokoro Y, Kobayashi M, Kasahara A, Jing Y, Shoulkamy MI, Meguro-Horike M, Kojima K, Kiyoi H, Sugiyama H, Nagase H, Tajima A, Hirao A.
    • Journal Title

      Cell Death Disease

      Volume: 14 Issue: 9 Pages: 642-642

    • DOI

      10.1038/s41419-023-06168-2

    • Peer Reviewed / Open Access
    • Data Source
      KAKENHI-PROJECT-23K18298, KAKENHI-PROJECT-23K14729, KAKENHI-PROJECT-21K08396, KAKENHI-PROJECT-22K06896, KAKENHI-PROJECT-22K08448, KAKENHI-PROJECT-23K06629, KAKENHI-PROJECT-23K06672, KAKENHI-PROJECT-23K07855, KAKENHI-PUBLICLY-22H05622, KAKENHI-PROJECT-23K27437, KAKENHI-PROJECT-23K27624
  • [Journal Article] Real-world data of MDS and CMML in Japan: results of JALSG clinical observational study-11 (JALSG-CS-11)2023

    • Author(s)
      Usuki Kensuke、Ohtake Shigeki、Honda Sumihisa、Kojima Kensuke、Kiyoi Hitoshi、et al
    • Journal Title

      International Journal of Hematology

      Volume: 119 Issue: 2 Pages: 130-145

    • DOI

      10.1007/s12185-023-03686-9

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-21K08396, KAKENHI-PROJECT-22K08490, KAKENHI-PROJECT-22K08518, KAKENHI-PROJECT-23K27624
  • [Journal Article] Enhanced TP53 reactivation disrupts MYC transcriptional program and overcomes venetoclax resistance in acute myeloid leukemias2023

    • Author(s)
      Nishida Yuki、Ishizawa Jo、Ayoub Edward、Montoya Rafael Heinz、Kojima Kensuke、Andreeff Michael、et al
    • Journal Title

      Science Advances

      Volume: 9 Issue: 48

    • DOI

      10.1126/sciadv.adh1436

    • Peer Reviewed / Open Access / Int'l Joint Research
    • Data Source
      KAKENHI-PROJECT-21K08396
  • [Journal Article] Real-world data of AML in Japan: results of JALSG clinical observational study-11 (JALSG-CS-11)2023

    • Author(s)
      Usuki Kensuke、Ohtake Shigeki、Honda Sumihisa、Kojima Kensuke、Miyazaki Yasushi、et al
    • Journal Title

      International Journal of Hematology

      Volume: 119 Issue: 1 Pages: 24-38

    • DOI

      10.1007/s12185-023-03677-w

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-21K08396, KAKENHI-PROJECT-22K08490, KAKENHI-PROJECT-22K08518, KAKENHI-PROJECT-23K27624
  • [Journal Article] Cyclin D2-positive mantle cell lymphoma with t(2;12)(p12;p13) arising in immune deficiency/dysregulation2023

    • Author(s)
      Kondo Takumi、Iguchi Mitsuko、Yoshida Shohei、Yoshino Tadashi、Kojima Kensuke
    • Journal Title

      Annals of Hematology

      Volume: 102 Issue: 9 Pages: 2639-2640

    • DOI

      10.1007/s00277-023-05330-2

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-21K08396
  • [Journal Article] Systemic Abscopal Effect of Low-dose Radiotherapy (2 Gy ×2) against Palatine Tonsil Follicular Lymphoma2022

    • Author(s)
      Togitani K, Asagiri T, Iguchi M, Igawa T, Yoshino T, Kojima K.
    • Journal Title

      Intern. Med.

      Volume: 61 Issue: 20 Pages: 3107-3110

    • DOI

      10.2169/internalmedicine.8968-21

    • ISSN
      0918-2918, 1349-7235
    • Year and Date
      2022-10-15
    • Language
      English
    • Peer Reviewed / Open Access
    • Data Source
      KAKENHI-PROJECT-20K07375, KAKENHI-PROJECT-21K08396
  • [Journal Article] Glucocorticoid-induced redistribution lymphocytosis in mantle cell lymphoma with hyaline vascular Castleman disease-like features2022

    • Author(s)
      Togitani Kazuto、Iguchi Mitsuko、Asagiri Tadashi、Ogasawara Fumiya、Murakami Ichiro、Kojima Kensuke
    • Journal Title

      Journal of Clinical and Experimental Hematopathology

      Volume: 62 Issue: 1 Pages: 46-51

    • DOI

      10.3960/jslrt.21024

    • NAID

      130008110815

    • ISSN
      1346-4280, 1880-9952
    • Language
      English
    • Peer Reviewed / Open Access
    • Data Source
      KAKENHI-PROJECT-21K08396
  • [Journal Article] Targeting VEGF with bevacizumab inhibits malignant effusion formation of primary human herpesvirus 8‐unrelated effusion large B‐cell lymphoma in vivo2022

    • Author(s)
      Ogasawara Fumiya、Higuchi Tomonori、Nishimori Tomohiro、Hashida Yumiko、Kojima Kensuke、Daibata Masanori
    • Journal Title

      Journal of Cellular and Molecular Medicine

      Volume: 26 Issue: 22 Pages: 5580-5589

    • DOI

      10.1111/jcmm.17570

    • Peer Reviewed / Open Access
    • Data Source
      KAKENHI-PROJECT-21K08396, KAKENHI-PROJECT-22K08434, KAKENHI-PROJECT-20K08673, KAKENHI-PROJECT-20K08714
  • [Journal Article] Diagnostic efficacy of <i>WT1</i> expression in asymptomatic acute promyelocytic leukemia2022

    • Author(s)
      江田 仁海、渡部 伸一朗、小笠原 史也、佐伯 恭昌、吉田 将平、砥谷 和人、武内 あか里、宮﨑 詩織、小島 研介
    • Journal Title

      Rinsho Ketsueki

      Volume: 63 Issue: 11 Pages: 1520-1524

    • DOI

      10.11406/rinketsu.63.1520

    • ISSN
      0485-1439, 1882-0824
    • Language
      Japanese
    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-21K08396
  • [Journal Article] Adult-onset Langerhans cell histiocytosis changing CNS lesion from pituitary to suprasellar extension2022

    • Author(s)
      Kadowaki Yuji、Nishiyama Mitsuru、Nakamura Makoto、Morisaka Hiroyuki、Fujimoto Shimpei、Terada Yoshio、Kojima Kensuke
    • Journal Title

      Endocrinology, Diabetes, Metabolism Case Reports

      Volume: 2022 Pages: 1-6

    • DOI

      10.1530/edm-22-0232

    • Peer Reviewed / Open Access
    • Data Source
      KAKENHI-PROJECT-21K08396, KAKENHI-PROJECT-22K08657, KAKENHI-PROJECT-17K09884
  • [Journal Article] Reagent-dependent pseudo-prolongation of activated partial thromboplastin time2021

    • Author(s)
      宮﨑 詩織、西田 愛恵、朝霧 正、重留 一貴、木田 和伸、久川 浩章、砥谷 和人、小島 研介
    • Journal Title

      Rinsho Ketsueki

      Volume: 62 Issue: 10 Pages: 1515-1518

    • DOI

      10.11406/rinketsu.62.1515

    • NAID

      130008113161

    • ISSN
      0485-1439, 1882-0824
    • Language
      Japanese
    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-21K08396
  • [Journal Article] Central Nervous System Involvement in Mantle Cell Lymphoma Presenting Magnetic Resonance Imaging Features of Mild Encephalitis/Encephalopathy with a Reversible Splenial Lesion2021

    • Author(s)
      Nakamura Makoto、Iwasa Hitomi、Kojima Kensuke
    • Journal Title

      Intern. Med.

      Volume: 60 Issue: 10 Pages: 1597-1600

    • DOI

      10.2169/internalmedicine.6386-20

    • NAID

      130008038569

    • ISSN
      0918-2918, 1349-7235
    • Year and Date
      2021-05-15
    • Language
      English
    • Peer Reviewed / Open Access
    • Data Source
      KAKENHI-PROJECT-17K09928, KAKENHI-PROJECT-21K08396
  • [Journal Article] Lead poisoning associated with an Indian-manufactured unauthorized dietary supplement2021

    • Author(s)
      砥谷 和人、江田 雅志、朝霧 正、小島 研介
    • Journal Title

      Rinsho Ketsueki

      Volume: 62 Issue: 4 Pages: 267-269

    • DOI

      10.11406/rinketsu.62.267

    • NAID

      130008035433

    • ISSN
      0485-1439, 1882-0824
    • Language
      Japanese
    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-21K08396
  • [Journal Article] Chronic myeloid leukemia with variant e13a3 (b2a3) <i>BCR-ABL1</i> as an ABL1 tyrosine kinase inhibitor-sensitive subtype2021

    • Author(s)
      砥谷 和人、朝霧 正、上岡 樹生、小島 研介
    • Journal Title

      Rinsho Ketsueki

      Volume: 62 Issue: 3 Pages: 180-185

    • DOI

      10.11406/rinketsu.62.180

    • NAID

      130008022236

    • ISSN
      0485-1439, 1882-0824
    • Language
      Japanese
    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-17K09928, KAKENHI-PROJECT-21K08396
  • [Journal Article] Development of a novel cell line‐derived xenograft model of primary herpesvirus 8‐unrelated effusion large B‐cell lymphoma and antitumor activity of birabresib in vitro and in vivo2021

    • Author(s)
      Nishimori Tomohiro、Higuchi Tomonori、Hashida Yumiko、Ujihara Takako、Taniguchi Ayuko、Ogasawara Fumiya、Kitamura Naoya、Murakami Ichiro、Kojima Kensuke、Daibata Masanori
    • Journal Title

      Cancer Medicine

      Volume: 10 Issue: 24 Pages: 8976-8987

    • DOI

      10.1002/cam4.4394

    • Peer Reviewed / Open Access
    • Data Source
      KAKENHI-PROJECT-19K08817, KAKENHI-PROJECT-19K17928, KAKENHI-PROJECT-20K08673, KAKENHI-PROJECT-20K08714, KAKENHI-PROJECT-21K08396
  • [Journal Article] Inhibition of translation initiation factor eIF4a inactivates heat shock factor 1 (HSF1) and exerts anti-leukemia activity in AML2021

    • Author(s)
      Nishida Yuki、Zhao Ran、Heese Lauren E.、Akiyama Hiroki、Patel Shreya、Jaeger Alex M.、Jacamo Rodrigo O.、Kojima Kensuke、Ma Man Chun John、Ruvolo Vivian R.、Chachad Dhruv、Devine William、Lindquist Susan、Davis R. Eric、Porco John A.、Whitesell Luke、Andreeff Michael、Ishizawa Jo
    • Journal Title

      Leukemia

      Volume: 35 Issue: 9 Pages: 2469-2481

    • DOI

      10.1038/s41375-021-01308-z

    • Peer Reviewed / Int'l Joint Research
    • Data Source
      KAKENHI-PROJECT-21K08396
  • [Journal Article] Prophylactic antiviral therapy for hepatitis B virus surface antigen‐positive patients with diffuse large B‐cell lymphoma treated with rituximab‐containing chemotherapy2021

    • Author(s)
      Yamauchi Nobuhiko、Maruyama Dai、Choi Ilseung、Atsuta Yoshiko、Sakai Rika、Miyashita Kazuho、Moriuchi Yukiyoshi、Tsujimura Hideki、Kubota Nobuko、Yamamoto Go、Igarashi Tadahiko、Izutsu Koji、Yoshida Shinichiro、Kojima Kensuke、・・・、Kusumoto Shigeru
    • Journal Title

      Cancer Science

      Volume: 112 Issue: 5 Pages: 1943-1954

    • DOI

      10.1111/cas.14846

    • Peer Reviewed / Open Access
    • Data Source
      KAKENHI-PROJECT-17K09928, KAKENHI-PROJECT-21K08396
  • [Journal Article] Acquired hypofibrinogenemia in patients with leukemia during steroid therapy2021

    • Author(s)
      小笠原史也、 伊藤孟彦、中村 真、佐伯恭昌、谷口亜裕子、 砥谷和人、小島研介
    • Journal Title

      Rinsho Ketsueki

      Volume: 62 Issue: 3 Pages: 193-195

    • DOI

      10.11406/rinketsu.62.193

    • NAID

      130008022252

    • ISSN
      0485-1439, 1882-0824
    • Language
      Japanese
    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-19K08817, KAKENHI-PROJECT-17K09928, KAKENHI-PROJECT-21K08396
  • [Journal Article] Targeting aberrant DNA hypermethylation as a driver of ATL leukemogenesis by using the new oral demethylating agent OR-21002020

    • Author(s)
      Watanabe Tatsuro、Yamashita Satoshi、Ureshino Hiroshi、Kamachi Kazuharu、Kurahashi Yuki、Fukuda-Kurahashi Yuki、Yoshida Nao、Hattori Naoko、Nakamura Hideaki、Sato Akemi、Kawaguchi Atsushi、Sueoka-Aragane Naoko、Kojima Kensuke、Okada Seiji、Ushijima Toshikazu、Kimura Shinya、Sueoka Eisaburo
    • Journal Title

      Blood

      Volume: 136 Issue: 7 Pages: 871-884

    • DOI

      10.1182/blood.2019003084

    • Peer Reviewed / Open Access
    • Data Source
      KAKENHI-PROJECT-20K07593, KAKENHI-PROJECT-20K07700, KAKENHI-PROJECT-20K08756, KAKENHI-PROJECT-17K09928, KAKENHI-PROJECT-19K17860
  • [Journal Article] Gastric emphysema in chemosensitive gastric diffuse large B cell lymphoma2020

    • Author(s)
      Nakamura Makoto、Saeki Kyosuke、Egashira Ryoko、Egashira Yoshiaki、Kojima Kensuke
    • Journal Title

      Annals of Hematology

      Volume: 99 Issue: 10 Pages: 2457-2458

    • DOI

      10.1007/s00277-020-04118-y

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-17K09928
  • [Journal Article] Treatment strategies for chronic lymphocytic leukemia in the era of novel targeted therapies2020

    • Author(s)
      小島 研介
    • Journal Title

      Rinsho Ketsueki

      Volume: 61 Issue: 9 Pages: 1275-1280

    • DOI

      10.11406/rinketsu.61.1275

    • NAID

      130007937063

    • ISSN
      0485-1439, 1882-0824
    • Language
      Japanese
    • Data Source
      KAKENHI-PROJECT-17K09928
  • [Journal Article] Treatment algorithm for Japanese patients with chronic lymphocytic leukemia in the era of novel targeted therapies2020

    • Author(s)
      Kojima Kensuke、Burger Jan A.
    • Journal Title

      Journal of Clinical and Experimental Hematopathology

      Volume: 60 Issue: 4 Pages: 130-137

    • DOI

      10.3960/jslrt.20002

    • NAID

      130007955989

    • ISSN
      1346-4280, 1880-9952
    • Language
      English
    • Peer Reviewed / Open Access / Int'l Joint Research
    • Data Source
      KAKENHI-PROJECT-17K09928
  • [Journal Article] Primary pulmonary diffuse large B cell lymphoma presenting as bulky bilateral lung tumors2020

    • Author(s)
      Saeki Kyosuke、Nakamura Makoto、Egashira Ryoko、Kojima Kensuke
    • Journal Title

      Annals of Hematology

      Volume: 100 Issue: 2 Pages: 577-578

    • DOI

      10.1007/s00277-020-04040-3

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-17K09928
  • [Journal Article] Clinical impact of the CONUT score in patients with multiple myeloma2020

    • Author(s)
      Okamoto S, Ureshino H*, Kidoguchi K, Kusaba K, Kizuka-Sano H, Sano H, Nishioka A, Yamaguchi K, Kamachi K, Itamura H, Yoshimura M, Yokoo M, Shindo T, Kubota Y, Ando T, Kojima K, Kawaguchi A, Sueoka E, Kimura S.
    • Journal Title

      Ann Hematol

      Volume: 99 Issue: 1 Pages: 113-119

    • DOI

      10.1007/s00277-019-03844-2

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-17K09928, KAKENHI-PROJECT-19K17860, KAKENHI-PROJECT-16K09851, KAKENHI-PROJECT-19K08812
  • [Journal Article] Locally distributed multicentric plasmacytomas in the ileum secondary to lymphoma chemoimmunotherapy2019

    • Author(s)
      Yokoo M, Kojima K, Sano H, Kai K, Arakawa F, Ohshima K, Matsunaga T, Kimura S.
    • Journal Title

      Ann Hematol

      Volume: 98 Issue: 6 Pages: 1501-1503

    • DOI

      10.1007/s00277-018-3543-y

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-17K09928
  • [Journal Article] BCR-ABL1- and CBFB-MYH11-positive chronic myeloid leukemia presenting with primary blast crisis and marrow fibrosis.2019

    • Author(s)
      Kidoguchi K, Kojima K*, Yokoo M, Kimura S.
    • Journal Title

      Ann Hematol.

      Volume: 98 Issue: 10 Pages: 2461-2462

    • DOI

      10.1007/s00277-019-03779-8

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-17K09928
  • [Journal Article] Oral ulceration: an unusual manifestation of lymphomatoid granulomatosis.2019

    • Author(s)
      Kidoguchi K, Yoshimura M, Kojima K*, Ureshino H, Egashira R, Yokoo M, Kai K, Egashira Y, Ohshima K, Ando T, Kimura S.
    • Journal Title

      Ann Hematol

      Volume: 98 Issue: 5 Pages: 1305-1307

    • DOI

      10.1007/s00277-018-3506-3

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-17K09928
  • [Journal Article] Is clinicopathological distinction of mucosa-associated lymphoid tissue lymphoma from Waldenstrom macroglobulinemia essential in MYD88 L265P mutation-positive cases?2019

    • Author(s)
      Kidoguchi K, Kojima K, Seki R, Nagafuji K, Ohshima K, Kimura S.
    • Journal Title

      Int J Hematol.

      Volume: 109 Issue: 3 Pages: 247-248

    • DOI

      10.1007/s12185-018-02585-8

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-17K09928
  • [Journal Article] Clinical impact of the CONUT score and mogamulizumab in adult T cell leukemia/lymphoma.2019

    • Author(s)
      Ureshino H, Kusaba K, Kidoguchi K, Sano H, Nishioka A, Itamura H, Yoshimura M, Yokoo M, Shindo T, Kubota Y, Ando T, Kojima K, Sueoka E, Kimura S.
    • Journal Title

      Annals of Hematology

      Volume: 98 Issue: 2 Pages: 465-471

    • DOI

      10.1007/s00277-018-3502-7

    • Peer Reviewed / Open Access
    • Data Source
      KAKENHI-PROJECT-16K09851, KAKENHI-PROJECT-17K09928, KAKENHI-PROJECT-16K09850, KAKENHI-PROJECT-19K08812
  • [Journal Article] Mitochondrial ClpP-Mediated Proteolysis Induces Selective Cancer Cell Lethality.2019

    • Author(s)
      Ishizawa J, Zarabi SF, Davis RE, Halgas O, Nii T, Jitkova Y, Zhao R, St-Germain J, Heese LE, Egan G, Ruvolo VR, Barghout SH, Nishida Y, Hurren R, Ma W, Gronda M, Link T, Wong K, Mabanglo M, Kojima K, Andreeff M
    • Journal Title

      Cancer Cell

      Volume: 35 Issue: 5 Pages: 721-737

    • DOI

      10.1016/j.ccell.2019.03.014

    • Peer Reviewed / Int'l Joint Research
    • Data Source
      KAKENHI-PROJECT-17K09928, KAKENHI-PROJECT-19K16774
  • [Journal Article] Primary Chest Wall MYC/BCL6 Double-hit Lymphoma with t (3;7) (q27;p12) and t (8;14) (q24;q32) Translocations2019

    • Author(s)
      Kamachi K, Kubota Y, Nagaie T, Yamaguchi K, Ogusu S, Kidoguchi K, Kusaba K, Kizuka-Sano H, Nishioka A, Yoshimura M, Yokoo M, Ando T, Kai K, Kojima K, Ohshima K, Sueoka E, Kimura S.
    • Journal Title

      Intern. Med.

      Volume: 58 Issue: 14 Pages: 2073-2077

    • DOI

      10.2169/internalmedicine.2532-18

    • NAID

      130007679517

    • ISSN
      0918-2918, 1349-7235
    • Year and Date
      2019-07-15
    • Language
      English
    • Peer Reviewed / Open Access
    • Data Source
      KAKENHI-PROJECT-16K09851, KAKENHI-PROJECT-16K09850
  • [Journal Article] ipridone ONC212 activates orphan G protein-coupled receptor GPR132 and integrated stress response in acute myeloid leukemia2019

    • Author(s)
      Nii T, Prabhu VV, Ruvolo V, Madhukar N, Zhao R, Mu H, Heese L, Nishida Y, Kojima K, Garnett MJ, McDermott U, Benes CH, Charter N, Deacon S, Elemento O, Allen JE, Oster W, Stogniew M, Ishizawa J, Andreeff M.
    • Journal Title

      Leukemia

      Volume: 33 Issue: 12 Pages: 2805-2816

    • DOI

      10.1038/s41375-019-0491-z

    • Peer Reviewed / Int'l Joint Research
    • Data Source
      KAKENHI-PROJECT-17K09928, KAKENHI-PROJECT-19K16774
  • [Journal Article] Feasibility of the Imatinib Stop Study in the Japanese Clinical Setting: Delightedly Overcome CML Expert Stop TKI Trial (DOMEST Trial).2018

    • Author(s)
      Fujisawa S, Ueda Y, Usuki K, Kobayashi K, Kondo E, Doki N, Nakao T, Kanda Y, Kosugi N, Kosug H, Kumagai T, Harada H, Shikami M, Maeda Y, Sakura T, Inokuchi K, Saito A, Nawa Y, Ogasawara M, Nishida J, Kondo T, Yoshida C, Kuroda H, Tabe Y, Maeda Y, Imajo K, Kojima K, Morita S, Komukai S, Kawaguchi A, Sakamoto J, Kimura S
    • Journal Title

      International Journal of Clinical Oncology

      Volume: 24 Issue: 4 Pages: 445-453

    • DOI

      10.1007/s10147-018-1368-2

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-17K09908, KAKENHI-PROJECT-17K09928
  • [Journal Article] Predictive gene signatures determine tumor sensitivity to MDM2 inhibition.2018

    • Author(s)
      Ishizawa J, Nakamaru K, Seki T, Tazaki K, Kojima K, Chachad D, Zhao R, Heese LE, Ma W, Ma MCJ, DiNardo CD, Pierce SA, Patel KP, Tse A, Davis RE, Rao A, Andreeff M.
    • Journal Title

      Cancer Res.

      Volume: in press

    • Peer Reviewed / Int'l Joint Research
    • Data Source
      KAKENHI-PROJECT-17K09928
  • [Journal Article] Predictive Gene Signatures Determine Tumor Sensitivity to MDM2 Inhibition.2018

    • Author(s)
      Ishizawa J, Nakamaru K, Seki T, Tazaki K, Kojima K, Chachad D, Zhao R, Heese L, Ma W, Ma MCJ, DiNardo C, Pierce S, Patel KP, Tse A, Davis RE, Rao A, Andreeff M.
    • Journal Title

      Cancer Res.

      Volume: 78 Issue: 10 Pages: 2721-2731

    • DOI

      10.1158/0008-5472.can-17-0949

    • Peer Reviewed / Int'l Joint Research
    • Data Source
      KAKENHI-PROJECT-17K09928
  • [Journal Article] Targeting of BMI-1 expression by the novel small molecule PTC596 in mantle cell lymphoma.2018

    • Author(s)
      Maeda A, Nishida Y, Weetall M, Cao L, Branstrom A, Ishizawa J, Nii T, Schober WD, Abe Y, Matsue K, Yoshimura M, Kimura S, Kojima K.
    • Journal Title

      Oncotarget.

      Volume: 19 Issue: 47 Pages: 28547-28560

    • DOI

      10.18632/oncotarget.25558

    • Peer Reviewed / Open Access / Int'l Joint Research
    • Data Source
      KAKENHI-PROJECT-17K09928
  • [Journal Article] Successful treatment of post-transplant relapsed adult T cell leukemia after cord blood transplantation with low-dose, short-term lenalidomide2018

    • Author(s)
      Ando Toshihiko、Kojima Kensuke、Sano Haruhiko、Kidoguchi Keisuke、Kusaba Kana、Yoshimura Mariko、Yokoo Masako、Kubota Yasushi、Nakamura Hideaki、Takase Yukari、Aishima Shinichi、Kimura Shinya
    • Journal Title

      Leukemia & Lymphoma

      Volume: in press Issue: 10 Pages: 1-4

    • DOI

      10.1080/10428194.2018.1427859

    • Peer Reviewed / Open Access
    • Data Source
      KAKENHI-PROJECT-16K09851, KAKENHI-PROJECT-17K09928
  • [Journal Article] The novel BMI-1 inhibitor PTC596 downregulates MCL-1 and induces p53-independent mitochondrial apoptosis in acute myeloid leukemia progenitor cells.2017

    • Author(s)
      Nishida Y, Maeda A, Kim MJ, Cao L, Kubota Y, Ishizawa J, AlRawi A, Kato Y, Iwama A, Fujisawa M, Matsue K, Weetall M, Dumble M, Andreeff M, Davis TW, Branstrom A, Kimura S, Kojima K.
    • Journal Title

      Blood Cancer J

      Volume: 17 Issue: 2 Pages: e527-e527

    • DOI

      10.1038/bcj.2017.8

    • Peer Reviewed / Acknowledgement Compliant / Open Access / Int'l Joint Research
    • Data Source
      KAKENHI-PROJECT-26461425, KAKENHI-PROJECT-16K09851, KAKENHI-PROJECT-17K09928
  • [Journal Article] Automatic digital quantification of bone marrow myeloma volume in appendicular skeletons - clinical implications and prognostic significance2017

    • Author(s)
      Nishida Yuki、Kimura Shinya、Mizobe Hideaki、Yamamichi Junta、Kojima Kensuke、Kawaguchi Atsushi、Fujisawa Manabu、Matsue Kosei
    • Journal Title

      Sci Rep.

      Volume: 7 Issue: 1 Pages: 12885-12885

    • DOI

      10.1038/s41598-017-13255-w

    • Peer Reviewed / Open Access
    • Data Source
      KAKENHI-PROJECT-17K09928
  • [Journal Article] Elderly patients with chronic myeloid leukemia benefit from a dasatinib dose as low as 20 mg.2017

    • Author(s)
      Itamura H, Kubota Y, Shindo T, Ando T, Kojima K, Kimura S
    • Journal Title

      Clin Lymph Myeloma Leuk

      Volume: 印刷中 Issue: 6 Pages: 370-374

    • DOI

      10.1016/j.clml.2017.02.023

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-26461451, KAKENHI-PROJECT-16K09851, KAKENHI-PROJECT-17K09928
  • [Journal Article] FZR1 loss increases sensitivity to DNA damage and consequently promotes murine and human B cell acute leukemia.2017

    • Author(s)
      Ishizawa J, Sugihara E, Kuninaka S, Mogushi K, Kojima K, Benton CB, Zhao R, Chachad D, Hashimoto N, Jacamo RO, Qiu Y, Yoo SY, Okamoto S, Andreeff M, Kornblau SM, Saya H.
    • Journal Title

      Blood

      Volume: 129 Issue: 14 Pages: 1958-1968

    • DOI

      10.1182/blood-2016-07-726216

    • Peer Reviewed / Open Access / Int'l Joint Research
    • Data Source
      KAKENHI-PROJECT-26461425, KAKENHI-PROJECT-17H01401, KAKENHI-PROJECT-15K06840
  • [Journal Article] ATF4 induction through an atypical integrated stress response to ONC201 triggers p53-independent apoptosis in hematological malignancies.2016

    • Author(s)
      Ishizawa J, Kojima K, Chachad D, Ruvolo P, Ruvolo V, Jacamo RO, Borthakur G, Mu H, Zeng Z, Tabe Y, Allen JE, Wang Z, Ma W, Lee HC, Orlowski R, Sarbassov dos D, Lorenzi PL, Huang X, Neelapu SS, McDonnell T, Miranda RN, Wang M, Kantarjian H, Konopleva M, Davis RE, Andreeff M.
    • Journal Title

      Sci Signal.

      Volume: 9 Issue: 415

    • DOI

      10.1126/scisignal.aac4380

    • Peer Reviewed / Int'l Joint Research
    • Data Source
      KAKENHI-PROJECT-15K08653, KAKENHI-PROJECT-26461425
  • [Journal Article] The pathophysiological significance of PPM1D and therapeutic targeting of PPM1D-mediated signaling by GSK2830371 in mantle cell lymphoma.2016

    • Author(s)
      Kojima K, Maeda A, Yoshimura M, Nishida Y, Kimura S.
    • Journal Title

      Oncotarget

      Volume: 7 Issue: 43 Pages: 69625-69637

    • DOI

      10.18632/oncotarget.11904

    • Peer Reviewed / Acknowledgement Compliant / Open Access
    • Data Source
      KAKENHI-PROJECT-26461425
  • [Journal Article] Results of the Phase I Trial of RG7112, a Small-Molecule MDM2 Antagonist in Leukemia.2016

    • Author(s)
      Andreeff M, Kelly KR, Yee K, Assouline S, Strair R, Popplewell L, Bowen D, Martinelli G, Drummond MW, Vyas P, Kirschbaum M, Iyer SP, Ruvolo V, Gonz&#225;lez GM, Huang X, Chen G, Graves B, Blotner S, Bridge P, Jukofsky L, Middleton S, Reckner M, Rueger R, Zhi J, Nichols G, Kojima K.
    • Journal Title

      Clinical Cancer Research

      Volume: 22 Issue: 4 Pages: 868-876

    • DOI

      10.1158/1078-0432.ccr-15-0481

    • Peer Reviewed / Int'l Joint Research
    • Data Source
      KAKENHI-PROJECT-26461425
  • [Journal Article] Pharmacological activation of wild-type p53 in the therapy of leukemia.2016

    • Author(s)
      Kojima K, Ishizawa J, Andreeff M.
    • Journal Title

      Exp Hematol

      Volume: 44 Issue: 9 Pages: 791-798

    • DOI

      10.1016/j.exphem.2016.05.014

    • Peer Reviewed / Acknowledgement Compliant / Int'l Joint Research
    • Data Source
      KAKENHI-PROJECT-26461425
  • [Journal Article] Ribosomal biogenesis and translational flux inhibition by the selective inhibitor of nuclear export (SINE) XPO1 antagonist KPT-185.2015

    • Author(s)
      Yoko Tabe, Kensuke Kojima, Shinichi Yamamoto, Kazumasa Sekihara, Hiromichi Matsushita, Richard Eric Davis, Zhiqiang Wang, Wencai Ma, Jo Ishizawa, Saiko Kazuno, Michael Kauffman, Sharon Shacham, Tsutomu Fujimura, Takashi Ueno, Takashi Miida, Michael Andreef
    • Journal Title

      PLoS One

      Volume: 10 Issue: 9 Pages: e0137210-e0137210

    • DOI

      10.1371/journal.pone.0137210

    • Peer Reviewed / Open Access / Int'l Joint Research
    • Data Source
      KAKENHI-PROJECT-15K08624, KAKENHI-PROJECT-15K08653, KAKENHI-PROJECT-26430145, KAKENHI-PROJECT-26461425
  • [Journal Article] Mitochondrial profiling of acute myeloid leukemia in the assessment of response to apoptosis modulating drugs.2015

    • Author(s)
      Ishizawa J, Kojima K, McQueen T, Ruvolo V, Chachad D, Nogueras-Gonzalez GM, Huang X, Pierceall WE, Dettman EJ, Cardone MH, Shacham S, Konopleva M, Andreeff M.
    • Journal Title

      PLoS One

      Volume: 10 Issue: 9 Pages: 2715-27

    • DOI

      10.1371/journal.pone.0138377

    • Peer Reviewed / Acknowledgement Compliant / Open Access / Int'l Joint Research
    • Data Source
      KAKENHI-PROJECT-26461425
  • [Journal Article] Reactivation of resolved infection with the hepatitis B virus immune escape mutant G145R during dasatinib treatment for chronic myeloid leukemia.2015

    • Author(s)
      Ando T, Kojima K, Isoda H, Eguchi Y, Honda T, Ishigami M, Kimura S.
    • Journal Title

      Int J Hematol.

      Volume: 101 Pages: 1-1

    • Data Source
      KAKENHI-PROJECT-26461425
  • [Journal Article] Expression, function, and targeting of the nuclear exporter chromosome region maintenance 1 (CRM1) protein.2015

    • Author(s)
      Ishizawa J, Kojima K, Hail N Jr, Tabe Y, Andreeff M.
    • Journal Title

      Pharmacol Ther.

      Volume: 153 Pages: 25-35

    • DOI

      10.1016/j.pharmthera.2015.06.001

    • Peer Reviewed / Int'l Joint Research
    • Data Source
      KAKENHI-PROJECT-15K08653, KAKENHI-PROJECT-26461425
  • [Journal Article] "Coexistence of ALK- anaplastic large cell lymphoma and CD4+ T-cell large granular lymphocytic leukemia "2015

    • Author(s)
      Kazuharu Kamachi1, Noriyasu Fukushima, Toshihiko Ando, Ken-ichi Sato, Koichi Ohshima, Masako Yokoo, Takero Shindo, Yasushi Kubota, Kensuke Kojima, Shinya Kimura
    • Journal Title

      Ann Hematol

      Volume: 94 Issue: 3 Pages: 539-540

    • DOI

      10.1007/s00277-014-2176-z

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-25461454, KAKENHI-PROJECT-26461425, KAKENHI-PROJECT-26461451, KAKENHI-PROJECT-25870130
  • [Journal Article] The novel combination of dual mTOR inhibitor AZD2014 and pan-PIM inhibitor AZD1208 inhibits growth in acute myeloid leukemia via HSF pathway suppression.2015

    • Author(s)
      Harada M, Benito J, Yamamoto S, Kaur S, Arslan D, Ramirez S, Jacamo R, Platanias L, Matsushita H, Fujimura T, Kazuno S, Kojima K, Tabe Y, Konopleva M.
    • Journal Title

      Oncotarget

      Volume: 6 Issue: 35 Pages: 37930-37947

    • DOI

      10.18632/oncotarget.6122

    • Peer Reviewed / Int'l Joint Research
    • Data Source
      KAKENHI-PROJECT-15K08653, KAKENHI-PROJECT-26430145, KAKENHI-PROJECT-26461425
  • [Journal Article] Preclinical activity of the novel BMI-1 inhibitor PTC-209 in acute myeloid leukemia: implications for leukemia therapy.2015

    • Author(s)
      Nishida Y, Maeda A, Chachad D, Ishizawa J, Yi Hua Q, Kornblau SM, Kimura S, Andreeff M, Kojima K.
    • Journal Title

      Cancer Science

      Volume: 106 Issue: 12 Pages: 1705-1713

    • DOI

      10.1111/cas.12833

    • Peer Reviewed / Acknowledgement Compliant / Open Access / Int'l Joint Research
    • Data Source
      KAKENHI-PROJECT-26461425
  • [Journal Article] MDM2 Inhibitor, Nutlin 3a, induces p53 dependent autophagy in acute leukemia by AMP kinase activation.2015

    • Author(s)
      Borthakur G, Duvvuri S, Ruvolo V, Tripathi DN, Piya S, Burks J, Jacamo R, Kojima K, Ruvolo P, Fueyo-Margareto J, Konopleva M, Andreeff M. MDM2 Inhibitor, Nutlin 3a, induces p53 dependent autophagy in acute leukemia by AMP kinase activation.
    • Journal Title

      PLoS One

      Volume: 10 Issue: 10 Pages: e0139254-e0139254

    • DOI

      10.1371/journal.pone.0139254

    • Peer Reviewed / Open Access / Int'l Joint Research
    • Data Source
      KAKENHI-PROJECT-26461425
  • [Journal Article] Small lymphocytic lymphoma presenting as bulky renal incidentaloma.2014

    • Author(s)
      Kamachi K, Kojima K, Nishijima A, Takeshita M, Ando T, Kimura S.
    • Journal Title

      Int J Hematol.

      Volume: 100 Issue: 2 Pages: 107-108

    • DOI

      10.1007/s12185-014-1609-8

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-26461425
  • [Journal Article] ABL tyrosine kinase inhibitor–induced pulmonary alveolar proteinosis in chronic myeloid leukemia2014

    • Author(s)
      Mariko Yoshimura, Kensuke Kojima, Rika Tomimasu, Noriyasu Fukushima, Shinichiro Hayashi, Eisaburo Sueoka, Shinya Kimura
    • Journal Title

      Int J Hematol

      Volume: 100 Issue: 6 Pages: 611-614

    • DOI

      10.1007/s12185-014-1666-z

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-25461454, KAKENHI-PROJECT-26461425
  • [Journal Article] Induction of p53-mediated transcription and apoptosis by Exportin-1 (XPO1) inhibition in mantle cell lymphoma.2014

    • Author(s)
      4.Yoshimura M, Ishizawa J, Ruvolo V, Dilip A, Quintas-Cardama A, McDonnell TJ, Neelapu SS, Kwak LW, Shacham S, Kauffman M, Tabe Y, Yokoo M, Kimura S, Andreeff M, Kojima K
    • Journal Title

      Cancer Sci.

      Volume: 105 Issue: 7 Pages: 795-801

    • DOI

      10.1111/cas.12430

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-24501306, KAKENHI-PROJECT-26461425
  • [Journal Article] Diffuse bone marrow uptake of fluorodeoxyglucose in a patient with aleukaemic acute lymphoblastic leukaemia.2014

    • Author(s)
      Kitamura H, Ando T, Kojima K, Komiya K, Sueoka-Aragane N, Kimura S.
    • Journal Title

      Br J Haematol.

      Volume: 166 Issue: 1 Pages: 2-2

    • DOI

      10.1111/bjh.12872

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-26461425
  • [Presentation] Enhanced p53 Activation By Dual Inhibition of MDM2 and XPO1 Disrupts MYC Transcriptional Program and Restores Sensitivity to BCL-2 Inhibition in Ven/HMA Resistant AML2021

    • Author(s)
      Yuki Nishida, Jo Ishizawa, Kensuke Kojima et al.
    • Organizer
      63rd ASH Annual Meeting and Exposition
    • Int'l Joint Research
    • Data Source
      KAKENHI-PROJECT-21K08396
  • [Presentation] FLT3阻害2018

    • Author(s)
      小島研介
    • Organizer
      第22回日本がん分子標的治療学会学術集会
    • Invited
    • Data Source
      KAKENHI-PROJECT-17K09928
  • [Presentation] The novel imipridone ONC212 highly synergizes with the BCL-2 inhibitor ABT-199 in AML and activates orphan receptor GPR132.2018

    • Author(s)
      Nii T, Ishizawa J, Prabhu VV, Ruvolo V, Madhukar N, Zhao R, Mu H, Heese L, Kojima K, Garnett M, McDermott U, Benes C, Charter N, Deacon S, Elemento O, Allen J, Oster W, Stogniewand M, Andreeff M.
    • Organizer
      018 American Association for Cancer Research (AACR) Annual Meeting
    • Int'l Joint Research
    • Data Source
      KAKENHI-PROJECT-17K09928
  • [Presentation] The Novel Imipridone ONC212 Induces Pronounced Anti-Leukemia Effects in Vitro and In Vivo and Is Highly Synergistic with the BCL-2 Inhibitor ABT-1992017

    • Author(s)
      Takenobu Nii, Jo Ishizawa, Varun Vijay Prabhu, Vivian Ruvolo, Neel Madhukar, Ran Zhao, Hong Mu, Lauren Heese, Kensuke Kojima, Mathew Garnett, Ultan McDermott, Cyril H Benes, Neil Charter, Sean Deacon, Olivier Elemento, Joshua E. Allen, Wolfgang Oster, Martin Stogniew and Michael Andreeff
    • Organizer
      59th Annual Meeting and Exposition
    • Int'l Joint Research
    • Data Source
      KAKENHI-PROJECT-17K09928
  • [Presentation] Downregulation of BMI-1 By the Small Molecule PTC596 Induces Mitochondrial Apoptosis in Mantle Cell Lymphoma2017

    • Author(s)
      Kensuke Kojima, Aya Maeda, Sho Okamoto, Yuki Nishida, Cao Liangl, Marla Weetall, Art Branstrom and Shinya Kimura
    • Organizer
      59th Annual Meeting and Exposition
    • Int'l Joint Research
    • Data Source
      KAKENHI-PROJECT-17K09928
  • [Presentation] Targeting of BMI-1 in mantle cell lymphoma2017

    • Author(s)
      Aya Maeda, Shinya Kimura, Kensuke Kojima
    • Organizer
      第76回日本癌学会学術総会
    • Data Source
      KAKENHI-PROJECT-17K09928
  • [Presentation] PTC299 Is a Novel DHODH Inhibitor That Modulates VEGFA mRNA Translation and Inhibits Proliferation of a Broad Range of Leukemia Cells2017

    • Author(s)
      Liangxian Cao, Arthur Branstrom, John Baird, Christopher Trotta, Joseph Colacino, Marianne T. Santaguida, Diane Heiser, Mark Ma, Kensuke Kojima, Stuart Peltz, Edward O'Mara, Robert Spiegel and Marla Weetall
    • Organizer
      59th Annual Meeting and Exposition
    • Int'l Joint Research
    • Data Source
      KAKENHI-PROJECT-17K09928
  • [Presentation] Inhibition of Translation Initiation and Heat Shock Factor 1 (HSF1): A Novel Strategy Targeting FLT3 Double Mutant and Non-FLT3 Mutant AML Progenitor/Stem Cells2017

    • Author(s)
      Jo Ishizawa, Ran Zhao, Lauren Heese, Alex Jaeger, Yuki Nishida, Rodrigo Jacamo, Kensuke Kojima, Man Chun John MA, Vivian Ruvolo, Dhruv Chachad, R. Eric Davis, William Devine, John A Porco Jr., Luke Whitesell and Michael Andreeff
    • Organizer
      59th Annual Meeting and Exposition
    • Int'l Joint Research
    • Data Source
      KAKENHI-PROJECT-17K09928
  • [Presentation] Automatic Digital Quantification of Bone Marrow Myeloma Volume in Appendicular Skeletons ― Clinical Implications and Prognostic Significance2017

    • Author(s)
      Yuki Nishida, Shinya Kimura, Hideaki Mizobe, Junta Yamamichi, Kensuke Kojima, Atsushi Kawaguchi, Manabu Fujisawa and Kosei Matsue
    • Organizer
      59th Annual Meeting and Exposition
    • Int'l Joint Research
    • Data Source
      KAKENHI-PROJECT-17K09928
  • [Presentation] The PPM1D inhibitor GSK2830371 has p53-dependent anti-lymphoma effects and enhances bortezomib-induced apoptosis in mantle cell lymphoma2016

    • Author(s)
      Kensuke Kojima, Mariko Yoshimura, Aya Maeda, Hiroaki Kitamura, Yuki Nishida, Shinya Kimura
    • Organizer
      American Association for Cancer Research (AACR) 2016 Annual Meeting
    • Place of Presentation
      New Orleans
    • Year and Date
      2016-04-19
    • Int'l Joint Research
    • Data Source
      KAKENHI-PROJECT-26461425
  • [Presentation] Preclinical activity of the novel BMI-1 inhibitor PTC-209 in acute myeloid leukemia2015

    • Author(s)
      Yuki Nishida, Aya Maeda, Shinya Kimura, Thomas W. Davis, Kensuke Kojima
    • Organizer
      日本血液学会総会
    • Place of Presentation
      金沢
    • Year and Date
      2015-10-17
    • Data Source
      KAKENHI-PROJECT-26461425
  • [Presentation] Targeting BMI-1 by the novel BMI-1 inhibitor PTC596 in acute leukemia2015

    • Author(s)
      Yuki Nishida, Aya Maeda, Liangxian Cao, Melissa Dumble, Shinya Kimura Thomas W. Davis and Kensuke Kojima
    • Organizer
      2015 AACR-NCI-EORTC Molecular Targets and Cancer Therapeutics Conference
    • Place of Presentation
      Boston
    • Year and Date
      2015-11-06
    • Int'l Joint Research
    • Data Source
      KAKENHI-PROJECT-26461425
  • [Presentation] マントル細胞リンパ腫におけるPPM1D阻害剤によるp53依存性のアポトーシス誘導効果2015

    • Author(s)
      吉村麻里子、木村晋也、小島研介
    • Organizer
      日本癌学会総会
    • Place of Presentation
      名古屋
    • Year and Date
      2015-10-10
    • Data Source
      KAKENHI-PROJECT-26461425
  • [Presentation] BMI-1 inhibition by PTC-209 induces mitochondrial apoptosis in acute myeloid leukemia cells2015

    • Author(s)
      Kensuke Kojima, Yuki Nishida, Aya Maeda, Dhruv Chachad, Hiroaki Kitamura, Jo Ishizawa, Michael Andreeff, Shinya Kimura
    • Organizer
      American Association for Cancer Research (AACR) 2015 Annual Meeting
    • Place of Presentation
      Philadelphia
    • Year and Date
      2015-04-21
    • Int'l Joint Research
    • Data Source
      KAKENHI-PROJECT-26461425
  • [Presentation] Induction of p53-mediated transcription and apoptosis by XPO1 inhibition in mantle cell lymphoma

    • Author(s)
      Kensuke Kojima
    • Organizer
      16th International p53 Workshop
    • Place of Presentation
      Stockholm
    • Year and Date
      2014-06-15 – 2014-06-19
    • Data Source
      KAKENHI-PROJECT-26461425
  • [Presentation] マントル細胞リンパ腫における、XPO1阻害によるp53依存性転写の誘導と細胞死

    • Author(s)
      小島研介
    • Organizer
      第18回日本がん分子標的治療学会
    • Place of Presentation
      仙台
    • Year and Date
      2014-06-25 – 2014-06-27
    • Data Source
      KAKENHI-PROJECT-26461425
  • [Presentation] p53と白血病

    • Author(s)
      小島研介
    • Organizer
      第76回日本血液学会学術総会
    • Place of Presentation
      大阪
    • Year and Date
      2014-10-31 – 2014-11-02
    • Invited
    • Data Source
      KAKENHI-PROJECT-26461425
  • [Presentation] Prognostic impact and targeting of BMI-1 in acute myeloid leukemia

    • Author(s)
      Yuki Nishida, Kensuke Kojima, Aya Maeda, Dhruv Chachad, Hiroaki Kitamura, Jo Ishizawa, Michael Andreeff, Steven Kornblau, Shinya Kimura
    • Organizer
      56th ASH Annual Meeting and Exposition
    • Place of Presentation
      San Francisco
    • Year and Date
      2014-12-06 – 2014-12-09
    • Data Source
      KAKENHI-PROJECT-26461425
  • 1.  Sueoka Eisaburo (00270603)
    # of Collaborated Projects: 1 results
    # of Collaborated Products: 1 results
  • 2.  荒金 尚子 (20321846)
    # of Collaborated Projects: 1 results
    # of Collaborated Products: 0 results
  • 3.  UENO Tsuyoshi
    # of Collaborated Projects: 0 results
    # of Collaborated Products: 1 results
  • 4.  FUKUSHIMA Noriyasu
    # of Collaborated Projects: 0 results
    # of Collaborated Products: 2 results
  • 5.  TANIGUCHI Ayuko
    # of Collaborated Projects: 0 results
    # of Collaborated Products: 1 results
  • 6.  三井田 孝
    # of Collaborated Projects: 0 results
    # of Collaborated Products: 1 results
  • 7.  田部 陽子
    # of Collaborated Projects: 0 results
    # of Collaborated Products: 4 results
  • 8.  久保田 寧
    # of Collaborated Projects: 0 results
    # of Collaborated Products: 4 results
  • 9.  服部 奈緒子
    # of Collaborated Projects: 0 results
    # of Collaborated Products: 1 results
  • 10.  渡邉 達郎
    # of Collaborated Projects: 0 results
    # of Collaborated Products: 1 results
  • 11.  木村 晋也
    # of Collaborated Projects: 0 results
    # of Collaborated Products: 2 results
  • 12.  片桐 誠一朗
    # of Collaborated Projects: 0 results
    # of Collaborated Products: 1 results
  • 13.  平尾 敦
    # of Collaborated Projects: 0 results
    # of Collaborated Products: 1 results
  • 14.  大畑 雅典
    # of Collaborated Projects: 0 results
    # of Collaborated Products: 1 results
  • 15.  樋口 智紀
    # of Collaborated Projects: 0 results
    # of Collaborated Products: 1 results
  • 16.  進藤 岳郎
    # of Collaborated Projects: 0 results
    # of Collaborated Products: 1 results

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