ONODERA Masafumi 小野寺雅史

… Alternative Names

小野寺雅史オノデラマサフミ

ONODERA Masahumi 小野寺雅史

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Researcher Number	10334062
Other IDs
Affiliation (Current)	2025: 国立研究開発法人国立成育医療研究センター, 遺伝子細胞治療推進センター, センター長 2025: 国立研究開発法人国立成育医療研究センター, 成育遺伝研究部, 部長
Affiliation (based on the past Project Information) *help	2022 – 2023: 国立研究開発法人国立成育医療研究センター, 遺伝子細胞治療推進センター, センター長 2016 – 2019: 国立研究開発法人国立成育医療研究センター, 成育遺伝研究部, 部長 2018: 国立成育医療研究センター, 成育遺伝研究部, 部長 2015: 国立研究開発法人国立成育医療研究センター, その他部局等, その他 2013: (独)国立成育医療研究センター, 部長 … More 2013: 国立成育医療研究センター研究所, 成育遺伝研究部 2012: 独立行政法人国立成育医療研究センター, その他部局等, その他 2009 – 2011: National Research Institute for Child Health and Development, 成育遺伝研究部, 部長 2007: University of Tsukuba, Graduate School of Comprehensive Human Sciences, Assistant Professor 2006: 筑波大学, 大学院人間総合科学研究科, 講師 2005: 筑波大学, 大学院・人間総合科学研究科, 講師 2001 – 2004: Institute of Clinical Med., Univ of Tsukuba, Div of Hematology, Assistant Professor, 臨床医学系, 講師 Less
Review Section/Research Field	Principal Investigator Biological Sciences / Pediatrics Except Principal Investigator Pediatrics / Basic Section 52050:Embryonic medicine and pediatrics-related / Biomolecular chemistry and related fields / Pediatrics / Hematology / Embryonic/Neonatal medicine / Neurology
Keywords	Principal Investigator ウイルス / 免疫学 / トランスレーショナルリサーチ / レトロウイルスベクター / 再生医学 / 遺伝子 / 癌 / 遺伝子治療 / regenrative medicine / translational research … More / immunology / virus / gene / 蛍光色素 / 移植片対宿主病 / 造血幹細胞移植 / 小児血液学 / VSV-G / 骨髄移植 / 胚性幹細胞 / 造血幹細胞 / EGFP / huKo / 蛍光色素蛋白質 / 発生・分化 / 脳・神経 … More Except Principal Investigator 遺伝子治療 / 早期診断 / 先天性免疫不全症 / SH2D1A / SAP(SLAM-associated protein) / hematopoietic stem cells / SP細胞 / 造血幹細胞 / 21水酸化酵素欠損症 / 先天性副腎皮質過形成 / レトロウィルスベクター / ウイルスベクター / P450チトクロームオキシダーゼ / 11β水酸化酵素欠損症 / アデノウィルス随伴ウィルスベクター / 先天性副腎皮質過形成症 / 質量分析 / 診断 / 糖鎖 / 新生児マススクリーニング / LC-MS / 糖鎖プライマー / 診断薬 / 糖鎖ライブラリー / 質量分析装置 / グリコサミノグリカン / ムコ多糖症 / 糖鎖プライマー法 / ゲノム編集 / 人工多能性幹細胞 / 生体分子 / 免疫学 / 遺伝子発現調節 / 自己炎症性疾患 / 食細胞機能異常症 / 感染症 / 炎症 / 慢性肉芽腫症 / 原発性免疫不全症 / vasculitis / early diagnosis / T lymphocytes / primary immunodeficiency / X-linked lymphoproliferative disease / Epstein-Barr Virus / T細胞活性化 / flow cytometry (フローサイトメトリー) / Epstein-Barrウィルス / リンパ球 / SAP (SLAM-associated protein) / Epstein-Barr ウイルス / 血管炎 / T細胞 / X連鎖性リンパ増殖症候群 / Epstein-Barrウイルス / plasticity / self-renewal / ABCG2 / bcrp-1 / ABC transporter / 自己複製能 / 肝幹細胞 / Gfi-1B / アダプター分子 / lnk / 血管内皮前駆細胞 / 造血肝細胞 / 可塑性 / 自己複製 / microchimerism / retroviralvector / crab-eatingmonkey / in utero gene therapy / in utero transplantation / 免疫寛容 / 異種移植 / 遺伝子導入 / サル / 子宮内胎児細胞移植 / カニクイザル / レトロウイルスベクター / 胎児遺伝子治療 / 子宮内細胞移植 / 癌 / ヒストン修飾 / エピジェネティクス / ゲノム / 遺伝子 / ウィルスベクター / 小児内分泌 / 線維芽細胞 / ips細胞 / アデノウィルス関連ウィルスベクター / 副腎皮質過形成 / 再生医療 / MPTP / 移植 / 皮膚 / 神経幹細胞 / Mashi-1 / レトロウイルス / ガレクチン / 皮膚幹細胞 / パーキンソン病 Less

Development of AAV vector for in vivo treatment for congenital adrenal hyperplasia
- Principal Investigator
  
  内木康博
- Project Period (FY)
  2022 – 2024
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Review Section
  
  Basic Section 52050:Embryonic medicine and pediatrics-related
- Research Institution
  National Center for Child Health and Development
Studies necessary to establish ideal HSC gene therapy for Wiskott Aldrich Syndrome
- Principal Investigator
  
  大津真
- Project Period (FY)
  2017 – 2019
- Research Category
  
  Grant-in-Aid for Scientific Research (B)
- Research Field
  
  Pediatrics
- Research Institution
  The University of Tokyo
Development of diagnostic probes for mucopolysaccharidosis based on saccharide primer method
- Principal Investigator
  
  Sato Toshinori
- Project Period (FY)
  2017 – 2018
- Research Category
  
  Grant-in-Aid for Challenging Research (Exploratory)
- Research Field
  
  Biomolecular chemistry and related fields
- Research Institution
  Keio University
Hyper-inflammation and gene therapy for chronic granulomatous disease
- Principal Investigator
  
  Kawai Toshinao
- Project Period (FY)
  2015 – 2017
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Research Field
  
  Pediatrics
- Research Institution
  National Center for Child Health and Development
Genome instability caused by EVI1 oncogene activation
- Principal Investigator
  
  KUME Akihiro
- Project Period (FY)
  2011 – 2013
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Research Field
  
  Pediatrics
- Research Institution
  Jichi Medical University
Extra-adrenal expression of Cyp21a1 for gene therapy of congenital adrenal hyperplasia
- Principal Investigator
  
  NAIKI Yasuhiro
- Project Period (FY)
  2010 – 2012
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Research Field
  
  Pediatrics
- Research Institution
  National Research Institute for Child Health and Development
Analysis of mechanisms of chronic GVHD post allo-SCT by marking with multicolor florescent proteinsPrincipal Investigator
- Principal Investigator
  
  ONODERA Masafumi
- Project Period (FY)
  2009 – 2011
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Research Field
  
  Pediatrics
- Research Institution
  National Research Institute for Child Health and Development
Development of the new retroviral vector system for stem cell gene therapy.Principal Investigator
- Principal Investigator
  
  ONODERA Masafumi
- Project Period (FY)
  2006 – 2007
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Research Field
  
  Pediatrics
- Research Institution
  University of Tsukuba
マルチカラーレトロウイルスベクターを用いた個体形成時の複数遺伝子競合的機能解析法Principal Investigator
- Principal Investigator
  
  小野寺雅史
- Project Period (FY)
  2005 – 2006
- Research Category
  
  Grant-in-Aid for Scientific Research on Priority Areas
- Review Section
  
  Biological Sciences
- Research Institution
  University of Tsukuba
レトロウイルスベクターを用いた養子免疫遺伝子細胞療法の確立Principal Investigator
- Principal Investigator
  
  小野寺雅史
- Project Period (FY)
  2003
- Research Category
  
  Grant-in-Aid for Scientific Research on Priority Areas
- Review Section
  
  Biological Sciences
- Research Institution
  University of Tsukuba
自己皮膚幹細胞を用いたパーキンソン病治療
- Principal Investigator
  
  望月秀樹
- Project Period (FY)
  2003 – 2004
- Research Category
  
  Grant-in-Aid for Exploratory Research
- Research Field
  
  Neurology
- Research Institution
  Juntendo University
レトロウイルスベクターを用いた養子免疫遺伝子細胞療法の確立Principal Investigator
- Principal Investigator
  
  小野寺雅史
- Project Period (FY)
  2002
- Research Category
  
  Grant-in-Aid for Scientific Research on Priority Areas
- Review Section
  
  Biological Sciences
- Research Institution
  University of Tsukuba
Molecular pathology of X-linked lymphopro liferative disease : Towards the development of the gene therapy
- Principal Investigator
  
  SUMAZAKI Ryo
- Project Period (FY)
  2002 – 2003
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Research Field
  
  Pediatrics
- Research Institution
  University of Tsukuba
Plasticity and diversity of hematopoietic stem cells
- Principal Investigator
  
  NAKAUCHI Hiromitsu
- Project Period (FY)
  2001 – 2003
- Research Category
  
  Grant-in-Aid for Scientific Research (A)
- Research Field
  
  Hematology
- Research Institution
  THE UNIVERSITY OF TOKYO
  University of Tsukuba
Establishment of in utero cell iransplantation and fetal gene therapy model using non-human primate
- Principal Investigator
  
  NAKAUCHI Hiromitsu
- Project Period (FY)
  1999 – 2001
- Research Category
  
  Grant-in-Aid for Scientific Research (A)
- Research Field
  
  Embryonic/Neonatal medicine
- Research Institution
  Univ. of Tsukuba

All 2022 2019 2018 2017 2015 2011 2010 2009 2008 2007 2006 2005

All Journal Article Presentation Book Patent

[Book] 講義録小児科学2008
- Author(s)
  小野寺雅史
- Total Pages
  790
- Publisher
  メジカルビュー社
- Description
  「研究成果報告書概要(和文)」より
- Data Source
  KAKENHI-PROJECT-18591180
[Book] 講義録小児科学2008
- Author(s)
  小野寺雅史
- Total Pages
  790
- Publisher
  メジカルビュー社
- Data Source
  KAKENHI-PROJECT-18591180
[Journal Article] Adeno-associated virus-mediated gene therapy for patient's fibroblasts, induced pluripotent stem sells, and a mouse model of congenital adrenal hyperplasia2022
- Author(s)
  Naiki Y, Miyado M, Shindo M, Horikawa R, Hasegawa Y, Katsumata N, Takada S, Akutsu H, Onodera M, Fukami M
- Journal Title
  
  Human Gene Therapy
  
  Volume: 33 Issue: 15-16 Pages: 801-809
- DOI
  10.1089/hum.2022.005
- Peer Reviewed / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-22K07950, KAKENHI-PROJECT-21K18298
[Journal Article] Fecal calprotectin rise in chronic granulomatous disease-associated colitis.2017
- Author(s)
  Nakazawa Y, Kawai T, Arai K, Tamura E, Uchiyama T, Onodera M.
- Journal Title
  
  J. Clin. Immunol.
  
  Volume: 37 Pages: 741-743
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-15K09677
[Journal Article] Persistent Impairment of T-Cell Regeneration in a Patient with Activated PI3K δ Syndrome.2017
- Author(s)
  Goto F, Uchiyama T, Nakazawa Y, Imai K, Kawai T, Onodera M
- Journal Title
  
  J Clin Immunol
  
  Volume: 37 Pages: 347-350
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-15K09677
[Journal Article] Single Cell-Based Vector Tracing in Patients with ADA-SCID Treated with Stem Cell Gene Therapy.2017
- Author(s)
  Igarashi Y, Uchiyama T, Minegishi T, Takahashi S, Watanabe N, Kawai T, Yamada M, Ariga T, Onodera M
- Journal Title
  
  Mol Ther Methods Clin Dev.
  
  Volume: 6 Pages: 8-16
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-15K09677
[Journal Article] 慢性肉芽腫症に合併した肉芽腫性間質性肺炎に対するサリドマイド治療2015
- Author(s)
  河合利尚、渡辺信之、横山、中澤裕美子、後藤文洋、内山徹、前川貴伸、樋口昌孝、放生雅章、小野寺雅史
- Journal Title
  
  日本小児リウマチ学会雑誌
  
  Volume: 6 Pages: 11-16
- NAID
  130007956758
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-15K09677
[Journal Article] Severe and Rapid Progression in Very Early-Onset Chronic Granulomatous Disease-Associated Colitis.2015
- Author(s)
  Kawai T, Arai K, Harayama S, Nakazawa Y, Goto F, Maekawa T, Tamura E, Uchiyama T, Onodera M
- Journal Title
  
  Journal if Clinical Immunology
  
  Volume: 35 Issue: 6 Pages: 583-588
- DOI
  10.1007/s10875-015-0180-2
- Peer Reviewed / Acknowledgement Compliant / Open Access / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-15K09676, KAKENHI-PROJECT-15K09677
[Journal Article] Growth promotion of genetically modified hematopoietic progenitors using antibody/c-Mpl chimera2011
- Author(s)
  Kawahara M, Chen J, Sogo T, Teng J, Otsu M, Onodera M, Nakauchi H, Ueda H, Nagamune T
- Journal Title
  
  Cytokine
  
  Volume: 55 Pages: 402-408
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-21591379
[Journal Article] Heterozygous ITGA2B R995W mutation inducing a constitutive activation of the αIIbss3 receptor affects proplatelet formation and causes congenital macrothrombocytopenia2011
- Author(s)
  Kunishima S, Kashiwagi H, Otsu M, Takayam N, Eto K, Onodera M, Miyajima Y, Takamatsu Y, Suzumiya J, Matsubara K, Tomiyama Y, S Hidehiko
- Journal Title
  
  Blood
  
  Volume: 117 Pages: 5479-5484
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-21591379
[Journal Article] Potent In Vitro and In Vivo Antitumor Activity of Sorafenib Against Human Intrahepatic Cholangiocarcinoma Cells2011
- Author(s)
  Sugiyama H, Onuki K, Ishige K, Baba N, Ueda T, Matsuda S, Takeuchi K, Onodera M, Nakanuma Y, Yamato M, Yamamoto M, Hyodo I, Shoda J
- Journal Title
  
  J Gastroenterol
  
  Volume: 46 Pages: 779789-779789
- NAID
  10029029679
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-21591379
[Journal Article] Time-lapse imaging reveals symmetric division of GFAP-expressing progenitors for expansion of postnatal dentate granule neurons2011
- Author(s)
  Namba T, Mochizuki H, Suzuki R, Onodera M, Yamaguchi M, Namiki H, Shioda S, Seki T
- Journal Title
  
  PLoS ONE
  
  Volume: 6 Pages: 25303-25303
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-21591379
[Journal Article] Osteomyelitis due to triethoprim/sulfamethoxazole-re sistant Edwardsiella tarda infection in a patient with X-linked chronic granulomatous disease2011
- Author(s)
  Kawai T, Kusakabe H, Seki A, Kobayashi S, Onodera M
- Journal Title
  
  Infection
  
  Volume: 39 Pages: 171-173
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-21591379
[Journal Article] Heterozygous ITGA2B R995W mutation inducing a constitutive activation of theαIIbβ3 receptor affects proplatelet formation and causes congenital macrothrombocytopenia2011
- Author(s)
  Kunishima S, Kashiwagi H, Otsu M, Takayam N, Eto K, Onodera M, Miyajima Y, Takamatsu Y, Suzumiya J, Matsubara K, Tomiyama Y, Saito H
- Journal Title
  
  Blood
  
  Volume: 117 Pages: 5479-5484
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-21591379
[Journal Article] Intracellular estrogen receptor-binding fragment associated antigen 9 exerts in vivo tumor promoting effects via its coiled-coil region2011
- Author(s)
  Maeyama Y, Otsu M, Kubo S, Yamano T, Iimura Y, Onodera M, Kondo S, Sakiyama Y, Ariga T
- Journal Title
  
  Int J Oncology
  
  Volume: 39 Pages: 41-49
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-21591379
[Journal Article] Enforced ROR(gamma) t expression in haematopoietic stem cells increases regulatory T cell number, which reduces immunoreactivity and attenuates hypersensitivity in vivo2011
- Author(s)
  Fujisawa Y, Nabekura T, Kawachi Y, Otsuka F, Onodera M
- Journal Title
  
  Asian Pac J Allergy Immunol
  
  Volume: 29 Pages: 86-93
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-21591379
[Journal Article] Osteomyelitis due to triethoprim/sulfamethoxazole-resistant Edwardsiella tarda infection in a patient with X-linked chronic granulomatous disease2011
- Author(s)
  Kawai T, Kusakabe H, Seki A, Kobayashi S, Onodera M
- Journal Title
  
  Infection
  
  Volume: 39 Pages: 171-173
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-21591379
[Journal Article] Material obesity impairs hippocampal BDNF production and spatial learning performance in young mouse offspring2011
- Author(s)
  Tozuka Y, Kumon M, Wada E, Onodera M, Mochizuki H, Wada K
- Journal Title
  
  Neurochem Int
  
  Volume: 57 Pages: 253-257
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-21591379
[Journal Article] Enforced ROR(gamma)t expression in haematopoietic stem cells increases regulatory T cell number, which reduces immuno reactivity and attenuates hypersensitivity in vivo2011
- Author(s)
  Fujisawa Y, Nabekura T, Kawachi Y, Otsuka F, Onodera M
- Journal Title
  
  Asian Pac J Allergy Immunol
  
  Volume: 29 Pages: 86-93
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-21591379
[Journal Article] Transactivation of the dopamine receptor 3 gene by a single provirus integration results in development of B cell lymphoma in transgenic mice generated from retrovirally transduced embryonic stem cells2010
- Author(s)
  Hirata Y Hamanaka S, Onodera M
- Journal Title
  
  Blood
  
  Volume: 115 Pages: 3930-3938
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-21591379
[Journal Article] Transactivation of the dopamine receptor 3 gene by a single provirus integration results in development of B cell lymphoma in transgenic mice generated from retrovirally transduced embryonic stem cells.2010
- Author(s)
  Hirata Y, Hamanaka S, Onodera M.
- Journal Title
  
  Blood
  
  Volume: 115 Pages: 3930-3938
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-21591379
[Journal Article] Phosphodiesterase III inhibition promotes differentiation and survival of oligodendrocyte progenitors and enhances regeneration of ischemic white matter lesions in the adult mammalian brain.2010
- Author(s)
  Miyamoto N, Tanaka R, Shimura H, Watanabe T, Mori H, Onodera M, Mochizuki H, Hattori N, Urabe T.
- Journal Title
  
  J Cereb Blood FlowMetab
  
  Volume: 30 Pages: 299-310
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-21591379
[Journal Article] Phosphodiesterase III inhibition promotes differentiation and survival of oligodendrocyte progenitors and enhances regeneration of ischemic white matter lesions in the adult mammalian brain2010
- Author(s)
  Miyamoto N, Tanaka R, Shimura H, Watanabe T, Mori H, Onodera M, Mochizuki H, Hattori N, Urabe T
- Journal Title
  
  J Cereb Blood FlowMetab
  
  Volume: 30 Pages: 299-310
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-21591379
[Journal Article] Material obesity impairs hippocampal BDNF production and spatial learning performance in young mouse offspring.2010
- Author(s)
  Tozuka Y, Kumon M, Wada E, Onodera M, Mochizuki H, Wada K.
- Journal Title
  
  Neurochem Int
  
  Volume: 57 Pages: 253-257
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-21591379
[Journal Article] Crucial role for pCREB signaling in the differentiation and survival of neural progenitors under chronic cerebral hypoperfusion2009
- Author(s)
  Miyamoto N, Tanaka R, Zhang N, Shimura H, Onodera M, Mochizuki H, Hattori N, Urabe T
- Journal Title
  
  Neuroscience
  
  Volume: 162 Pages: 525-536
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-21591379
[Journal Article] Gain-of-function of mutated c-Cbl tumour suppressor associated with myeloid neoplasms with 11q UPD2009
- Author(s)
  Sanada M, Suzuki T, Shih LY, Otsu M, Kato Mo, Yamazaki S, Tamura A, Honda H, Mamiko, Yanagimoto S, Kumano K, Oda H, Yamagata T, Takita Junko, Gotoh N, Nakazaki K, Kawamata N, Onodera M, Nobuyoshi M, Hayashi Y, Harada H, Kurokawa M, Chiba S, Mori1 H, Ozawa K, Omine M, Hirai H, Nakauchi H, Koeffler HP, Ogawa S
- Journal Title
  
  Nature
  
  Volume: 460 Pages: 904-908
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-21591379
[Journal Article] Definiti ve proof for direct reprogramming of hematopoietic cells to pluripotency2009
- Author(s)
  Okabe M, Otsu M, Ahn DH, Kobayashi T, Morita Y, Wakiyama Y, Onodera M, Eto K, Ema H, Nakauchi H
- Journal Title
  
  Blood
  
  Volume: 114 Pages: 1764-1767
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-21591379
[Journal Article] Identification of tumor-initiating cells in a highly aggressive brain tumor using promoter activity of nucleostemin2009
- Author(s)
  Tamase A, Muraguchi T, Naka K, Hoshii T, Ohmura M, Kinoshita M, Tanaka S, Shugo H, Ooshio T, Nakada M, Sawamoto K, Onodera M, Matsumoto K, Oshima M, Asano M, Saya H, Okano H, Suda T, Hamada J, Hirao A
- Journal Title
  
  Proc Natl Acad Sci USA
  
  Volume: 106 Pages: 17163-17168
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-21591379
[Journal Article] Kinetics and effect of integrin expression in human CD34+cells during MLV-derived retroviral transduction using a recombinant fibronectin for stem cell gene therapy2009
- Author(s)
  Horiuchi Y, Onodera M, Miyagawa Y, Sato B, Onda K, Katagiri YU, Okita H, Okada M, Otsu M, Kume A, Okuyama T, Fujimoto J, Kuratsuji T, Kiyokawa N
- Journal Title
  
  Hum Gene Ther
  
  Volume: 20 Pages: 777-783
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-21591379
[Journal Article] T cell growth control using hapten-specific antibody/interleukin-2 receptor chimera2009
- Author(s)
  Sogo T, Kawahara M, Ueda H, Otsu M, Onodera M, Nakauchi H, Nagamune T
- Journal Title
  
  Cytokine
  
  Volume: 46 Pages: 127-136
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-21591379
[Journal Article] The induction of tumor-specific CD4+T cells via major histocompatibility complex class II is required to gain optimal anti-tumor immunity against B16 melanoma cell line in tumor immunotherapy using dendritic cells2009
- Author(s)
  Fujisawa Y, Nabekura T, Nakao T, Nakamura Y, Takahashi T, Kawachi Y, Otsuka F, Onodera M
- Journal Title
  
  Exp Dermatol
  
  Volume: 18 Pages: 396-403
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-21591379
[Journal Article] Gene and cell therapy for relapsed leukemia after allo-stem cell transplantation2008
- Author(s)
  Onodera M
- Journal Title
  
  Frontiers in Bioscience 13
  
  Pages: 3408-3414
- Description
  「研究成果報告書概要(欧文)」より
- Data Source
  KAKENHI-PROJECT-18591180
[Journal Article] Gene and cell therapy for relapsed leukemia after allo-stem cell transplantation.2008
- Author(s)
  Onodera M
- Journal Title
  
  Frontiers in Bioscience 13
  
  Pages: 3408-3414
- Description
  「研究成果報告書概要(和文)」より
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-18591180
[Journal Article] Child-health and developmental medicine2008
- Author(s)
  Onodera M
- Journal Title
  
  MEDICAL VIEW 790
- Description
  「研究成果報告書概要(欧文)」より
- Data Source
  KAKENHI-PROJECT-18591180
[Journal Article] Gene and cell therapy for relapsed leukemia after allo-stem cell transpl antation2007
- Author(s)
  Onodera M
- Journal Title
  
  Gene Therapy 2007
  
  Pages: 286-295
- Description
  「研究成果報告書概要(和文)」より
- Data Source
  KAKENHI-PROJECT-18591180
[Journal Article] Gene and cell therapy for relapsed leukemia after allo-stem cell transplantation2007
- Author(s)
  Onodera M
- Journal Title
  
  Gene Therapy 2007
  
  Pages: 286-295
- Description
  「研究成果報告書概要(欧文)」より
- Data Source
  KAKENHI-PROJECT-18591180
[Journal Article] Gene and cell therapy for relapsed leukemia after allo-stem cell transplantation.2007
- Author(s)
  Onodera Masafumi
- Journal Title
  
  Gene Therapy
  
  Pages: 286-294
- Data Source
  KAKENHI-PROJECT-17045005
[Journal Article] Gene and cell therapy for relapsed leukemia after allo-stem cell transplantation.2007
- Author(s)
  Onodera Masafumi
- Journal Title
  
  Gene Therapy
- Data Source
  KAKENHI-PROJECT-18591180
[Journal Article] Application of HSVtk suicide gene to X-SCID gene therapy : Ganciclovir treatment offsets gene corrected X-SCID B cells.2006
- Author(s)
  Uchiyama T, Kumaki S, Ishikawa Y, Onodera M, Sato M, Du W, Sasahara Y, Tanaka N, Sugamura K, Tsuchiya S.
- Journal Title
  
  Biochem Biophys Res Commun 341(2)
  
  Pages: 391-398
- Data Source
  KAKENHI-PROJECT-17045005
[Journal Article] Potent vaccine therapy with dendritic cells genetically modified by the retroviral vector GCDNsap.2006
- Author(s)
  Nabekura T, Otsu M, Nagasawa T, Nakauchi H, Onodera M.
- Journal Title
  
  Molecular Therapy 13(2)
  
  Pages: 301-309
- Data Source
  KAKENHI-PROJECT-17045005
[Journal Article] An in vivo assay for retrovirally transduced human peripheral T lymphocytes using non-obese diabetic/ severe combined immunodeficiency mice.2005
- Author(s)
  Kaneko S, Nagasawa T, Nakauchi H, Onodera M.
- Journal Title
  
  Exp Hematol 33(1)
  
  Pages: 35-41
- Data Source
  KAKENHI-PROJECT-17045005
[Journal Article] Parvovirus nonstructural proteins induce an epigenetic modification through histone acetylation in host genes and revert tumor malignancy to benignancy.2005
- Author(s)
  Iseki H, Shimizukawa R, Sugiyama F, Kunita S, Iwama A, Onodera M, Nakauchi H, Yagami K.
- Journal Title
  
  J Virol 79(14)
  
  Pages: 8886-8893
- Data Source
  KAKENHI-PROJECT-17045005
[Journal Article] Possibility for neurogenesis in substantia nigra of parkinsonian brain.2005
- Author(s)
  Yoshimi K, Ren YR, Seki T, Yamada M, Hayakawa H, Ooizumi H, Onodera M, Saito Y, Murayama S, Okano H, Mizuno Y, Mochizuki H.
- Journal Title
  
  Ann Neurol 58(1)
  
  Pages: 31-40
- Data Source
  KAKENHI-PROJECT-17045005
[Journal Article] The fate of neural progenitor cells expressing astrocytic and radial glial markers in the postnatal rat dentate gyrus.2005
- Author(s)
  Namba T, Mochizuki H, Onodera M, Mizuno Y, Namiki H, Seki T.
- Journal Title
  
  Eur J Neurosci 22(8)
  
  Pages: 1928-1941
- Data Source
  KAKENHI-PROJECT-17045005
[Patent] 蛍光蛋白質を発現とるトランスジェニック非ヒト動物2006
- Inventor(s)
  小野寺雅史他
- Industrial Property Rights Holder
  学校法人明治大学/学校法人順天堂
- Industrial Property Number
  2006-347487
- Filing Date
  2006-12-25
- Description
  「研究成果報告書概要(和文)」より
- Data Source
  KAKENHI-PROJECT-18591180
[Presentation] 糖鎖プライマー法を用いたムコ多糖症の診断基質の開発2019
- Author(s)
  八木柚香、渡辺摩周、松林慶一、中島英規、小野寺雅史、佐藤智典
- Organizer
  第68回高分子学会年次大会
- Data Source
  KAKENHI-PROJECT-17K19208
[Presentation] ムコ多糖症の新生児マススクリーニングに向けたGAG型オリゴ糖基質の開発2018
- Author(s)
  渡辺摩周、松林慶一、小野寺雅史、市田悠、中島英規、佐藤智典
- Organizer
  日本化学会第９８春季年会
- Data Source
  KAKENHI-PROJECT-17K19208
[Presentation] 胸腺に多発性肉芽腫性病変を合併した慢性肉芽腫症腸炎の乳児例2017
- Author(s)
  金森啓太、田村英一郎、小野寺雅史、益田博司、中尾寛、窪田満、石黒精、河合利尚
- Organizer
  第49回小児感染症学会
- Data Source
  KAKENHI-PROJECT-15K09677
[Presentation] 本邦における慢性肉芽腫症患者の解析2017
- Author(s)
  水上智之、岡田真由美、西村豊樹、河合利尚、小野寺雅史、今井耕輔、布井博幸
- Organizer
  第120回小児科学会学術集会
- Data Source
  KAKENHI-PROJECT-15K09677
[Presentation] 慢性肉芽腫症に合併した肝膿瘍の検討2017
- Author(s)
  田村英一郎、河合利尚、八木久子、西田豊、荒川浩一、内山徹、小野寺雅史
- Organizer
  第49回小児感染症学会
- Data Source
  KAKENHI-PROJECT-15K09677
[Presentation] AN IMPAIRMENT OF ROS PRODUCTION IN MONOCYTES/MACROPHAGES MAY BE ASSOCIATED WITH INDUCTION OF GRANULOMATOUS ENTERITIS.2017
- Author(s)
  Kawai T, Tamura E, Yokoyama M, Watanabe N, Nanbu M, Uchiyama T, Onodera M
- Organizer
  European society for immunodeficiencies
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-15K09677
[Presentation] 造血幹細胞遺伝子治療を行った慢性肉芽腫症2015
- Author(s)
  河合利尚、中澤裕美子、後藤文洋、内山徹、清谷知賀子、松本公一、宮入烈、布井博幸、奥山虎之、小野寺雅史
- Organizer
  小児科学会
- Place of Presentation
  大阪
- Year and Date
  2015-04-16
- Data Source
  KAKENHI-PROJECT-15K09677
[Presentation] 超早期発症型の重症慢性肉芽腫症関連腸炎2015
- Author(s)
  河合利尚、中澤裕美子、後藤文洋、内山徹、新井勝大、小野寺雅史
- Organizer
  小児リウマチ学会
- Place of Presentation
  金沢
- Year and Date
  2015-10-10
- Data Source
  KAKENHI-PROJECT-15K09677
[Presentation] A Gene Therapy Clinical Study of a Patient with Chronic Granulomatous Disease2015
- Author(s)
  Kawai T, Goto F, Nakazawa Y, Uchiyama T, Watanabe N, Yagita M, Igarashi Y, Mizukami T, Nunoi H, Onodera M
- Organizer
  日本遺伝子治療学会
- Place of Presentation
  大阪
- Year and Date
  2015-07-25
- Data Source
  KAKENHI-PROJECT-15K09677
[Presentation] 遺伝子治療における我が国と欧米の違い2011
- Author(s)
  小野寺雅史
- Organizer
  第1回国際協力遺伝病遺伝子治療フォーラム
- Place of Presentation
  東京
- Data Source
  KAKENHI-PROJECT-21591379
[Presentation] An effect of the transcription factor ZFP809 on gene silencing of the retroviral vectors2010
- Author(s)
  Tadokoro K, Ichida Y, Onodera M
- Organizer
  The 33nd Annual Meeting of the Molecular Biology Society of Japan
- Place of Presentation
  Kobe
- Data Source
  KAKENHI-PROJECT-21591379
[Presentation] 我が国における遺伝子医薬品承認に向けての課題と取組み2010
- Author(s)
  小野寺雅史
- Organizer
  第8回遺伝子治療シンポジウム
- Place of Presentation
  大阪
- Year and Date
  2010-02-05
- Data Source
  KAKENHI-PROJECT-21591379
[Presentation] 我が国における遺伝子医薬品承認に向けての課題と取組み2010
- Author(s)
  小野寺雅史
- Organizer
  第8回遺伝子治療シンポジウム
- Place of Presentation
  大阪
- Year and Date
  2010-02-05
- Data Source
  KAKENHI-PROJECT-21591379
[Presentation] 我が国における遺伝子医薬品承認に向けての課題と取組み2009
- Author(s)
  小野寺雅史
- Organizer
  第9回小児免疫リウマチ研究会
- Place of Presentation
  東京
- Year and Date
  2009-04-10
- Data Source
  KAKENHI-PROJECT-21591379
[Presentation] Kinetics and defect of integrin expression on human CD34+cells during MLV-derived retroviral transduction with a recombinant fibronectin for stem cell gene therapy2009
- Author(s)
  Horiuchi Y Onodera M, Miyagawa Y, Sato B, Onda K, Katagiri YU, Okita H, Okada M, Otsu M, Kume A, Okuyama T, Fujimoto J, Kuratsuji T, Kiyokawa N
- Organizer
  第15回日本遺伝子治療学会
- Place of Presentation
  吹田
- Year and Date
  2009-07-09
- Data Source
  KAKENHI-PROJECT-21591379
[Presentation] 小児難治性疾患に対する遺伝子細胞治療の発展に向けて2009
- Author(s)
  小野寺雅史
- Organizer
  第9回小児免疫リウマチ研究会
- Place of Presentation
  東京
- Year and Date
  2009-04-10
- Data Source
  KAKENHI-PROJECT-21591379
[Presentation] A reciprocal regulation between PAX2 and PAX62009
- Author(s)
  Tadokoro K, Azuma N, Onodera M
- Organizer
  The 32nd Annual Meeting of the Molecular Biology Society of Japan
- Place of Presentation
  Yokohama
- Year and Date
  2009-12-10
- Data Source
  KAKENHI-PROJECT-21591379
[Presentation] An immunotherapy approach with dendritic cells genetically modified to express the tumor-associated antigen, HER22007
- Author(s)
  Tsukasa NABEKURA, Toshiro NAGASAWA, Hiromitsu NAKAUCHI, and Masafumi ONODERA
- Organizer
  日本免疫学会
- Place of Presentation
  東京
- Data Source
  KAKENHI-PROJECT-18591180
[Presentation] FEASIBILITY OF VACCINE THERAPY WITH DENDRITIC CELLS GENETICALLY MODIFIED TO EXPRESS THE TUMOR-ASSOCLATED ANTIGEN HER22007
- Author(s)
  Tsukasa Nabekura, Toshiro Nagasawa, Hiromitsu Nakauchi, and Masafumi Onodera
- Organizer
  第13回日本遺伝子治療学会
- Place of Presentation
  国際医学交流センター(愛知がんセンター)
- Data Source
  KAKENHI-PROJECT-18591180
[Presentation] An immunotherapy approach with dendritic cells gentically modified to express the tumor-associated antigen,HER22007
- Author(s)
  Tsukasa Nabekura, Toshiro Nagasawa, Hiromitsu Nakauchi, and Masafumi Onodera
- Organizer
  第37回日本免疫学会
- Place of Presentation
  東京
- Description
  「研究成果報告書概要(和文)」より
- Data Source
  KAKENHI-PROJECT-18591180
[Presentation] Opposite effects of an integration site on expression of the transgene-Genesilencing or Leukemogenesis2007
- Author(s)
  Onodera M
- Organizer
  5th Conference on Stem Cell Gene Thrapy
- Place of Presentation
  Thessaloniki, Greek
- Description
  「研究成果報告書概要(欧文)」より
- Data Source
  KAKENHI-PROJECT-18591180
[Presentation] Gene Therapy for Hematologic Malignancy2007
- Author(s)
  Masafumi Onodera
- Organizer
  American Society of Gene Therapy 10th Annual Meeting
- Place of Presentation
  Washington State Convention & Trade Center, Seattle, WA, USA
- Year and Date
  2007-05-30
- Data Source
  KAKENHI-PROJECT-18591180
[Presentation] Opposite effects of an integration site on expression of the transgene-Genesilencing or Leukemogenesis2007
- Author(s)
  Masafumi Onodera
- Organizer
  IVth Conference on Stem Cell Gene Thrapy
- Place of Presentation
  Thessaloniki, Halkidiki, Greece
- Data Source
  KAKENHI-PROJECT-18591180
[Presentation] FEASIBLITY OF VACCINE THERAPY WITH DENDRITIC CELLS GENETIC ALLY MODIFIED TO EXPRESS THE TUMOR-ASSOCIATED ANTIGEN HER22007
- Author(s)
  Tsukasa Nabekura, Toshiro Nagasawa, Hiromitsu Nakauchi, and Masafumi Onodera
- Organizer
  1第13回日本遺伝子治療学会
- Place of Presentation
  国際医学交流センター(愛知がんセンター)
- Description
  「研究成果報告書概要(和文)」より
- Data Source
  KAKENHI-PROJECT-18591180
[Presentation] Gene Therapy for Hematologic Malignancy2007
- Author(s)
  Onodera M
- Organizer
  ASGT 10th Annual Meeting
- Place of Presentation
  Seattle, WA
- Description
  「研究成果報告書概要(欧文)」より
- Data Source
  KAKENHI-PROJECT-18591180
[Presentation] Gene Therapy for Hematologic Malignancy2007
- Author(s)
  Masafumi Onodera
- Organizer
  American Society of Gene Therapy 10^th Annual Meeting
- Place of Presentation
  Washington State Convention & Trade Center, Seattle, WA,USA
- Year and Date
  2007-05-30
- Description
  「研究成果報告書概要(和文)」より
- Data Source
  KAKENHI-PROJECT-18591180

1. NAKAUCHI Hiromitsu (40175485)

# of Collaborated Projects: 4 results

# of Collaborated Products: 0 results
2. NAIKI Yasuhiro (20470007)

# of Collaborated Projects: 2 results

# of Collaborated Products: 1 results
3. SHIBUYA Akira (80216027)

# of Collaborated Projects: 2 results

# of Collaborated Products: 0 results
4. 大津真 (30361330)

# of Collaborated Projects: 2 results

# of Collaborated Products: 1 results
5. 深見真紀 (40265872)

# of Collaborated Projects: 2 results

# of Collaborated Products: 1 results
6. KUME Akihiro (10264293)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
7. SHIBUYA Kazuko (00302406)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
8. IWAMA Atsushi (70244126)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
9. EMA Hideo (50344445)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
10. SUMAZAKI Ryo (40163050)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
11. OKUYAMA Torayuki (40177192)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
12. Kawai Toshinao (20328305)

# of Collaborated Projects: 1 results

# of Collaborated Products: 11 results
13. Sato Toshinori (00162454)

# of Collaborated Projects: 1 results

# of Collaborated Products: 2 results
14. 望月秀樹 (90230044)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
15. 大河内仁志 (30185235)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
16. 卜部貴夫 (60291663)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
17. 水野美邦 (30049043)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
18. 勝又規行 (10260340)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
19. 中村幸夫 (60231479)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
20. 森尾友宏 (30239628)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
21. 頼貞儀 (30739925)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
22. 中島英規 (30450620)

# of Collaborated Projects: 1 results

# of Collaborated Products: 2 results
23. TERAO Keiji

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
24. 内山徹

# of Collaborated Projects: 0 results

# of Collaborated Products: 1 results

ONODERA Masafumi 小野寺 雅史

小野寺 雅史 オノデラ マサフミ

ONODERA Masahumi 小野寺 雅史

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Analysis of mechanisms of chronic GVHD post allo-SCT by marking with multicolor florescent proteinsPrincipal Investigator

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Development of the new retroviral vector system for stem cell gene therapy.Principal Investigator

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マルチカラーレトロウイルスベクターを用いた個体形成時の複数遺伝子競合的機能解析法Principal Investigator

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レトロウイルスベクターを用いた養子免疫遺伝子細胞療法の確立Principal Investigator

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レトロウイルスベクターを用いた養子免疫遺伝子細胞療法の確立Principal Investigator

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ONODERA Masafumi 小野寺雅史

小野寺雅史オノデラマサフミ

ONODERA Masahumi 小野寺雅史

[Book] 講義録小児科学2008