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ITO KEN-ICHI  伊藤 研一

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Ito Ken-ichi  伊藤 研一

ITO Ken-ichi  伊藤 研一

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Researcher Number 10334905
Other IDs
External Links
Affiliation (Current) 2025: 信州大学, 学術研究院医学系, 教授
Affiliation (based on the past Project Information) *help 2017 – 2023: 信州大学, 学術研究院医学系, 教授
2014 – 2015: 信州大学, 学術研究院医学系, 教授
2013: 信州大学, 医学部, 准教授
2004 – 2006: 信州大学, 医学部附属病院, 講師
Review Section/Research Field
Principal Investigator
General surgery / Basic Section 55010:General surgery and pediatric surgery-related
Except Principal Investigator
Thoracic surgery
Keywords
Principal Investigator
甲状腺癌 / 新規治療戦略 / 未分化癌 / 分子標的薬 / 稀少癌 / 未分化転化 / 転写因子 / 甲状腺未分化癌 / 分子機構 / 遺伝子変異 … More / 遺伝子発現 / 発症機序 / 治療標的分子の探索 / EpCAM / 薬剤耐性機構 / マイクロアレイ / トランスレーショナルリサーチ / 癌 / 抗がん剤耐性機構 / がんの進展 / 癌の進展 / 網羅的遺伝子変異解析 / 浸潤 / 分子腫瘍学 / 網羅的遺伝子発現解析 / Transcription factor / Mechanisms of drug resistance / Chemotherapeutic sensitivity / Breast cancer / 抗癌剤耐性機構 / 抗癌剤感受性 / 乳癌 / 癌のバイオロジー / 甲状腺癌未分化癌 / 上皮間葉転換 / 稀少癌のバイオロジー / 分子標的の探索 / 希少癌のバイオロジー / 新規治療標的の開発 … More
Except Principal Investigator
Wnt / Versican / Chodroitin-6-sulphate / Glucosaminoglycan / Proteoglycan / APC gene / β catenin / β catenin signal / Cardiac myxoma / βカテキン / 糖タンパク / βカテニン / Wntシグナル / 粘液腫 / 心臓 / バーシカン / コンドロイチン6硫酸 / グリコサミノグリカン / プロテオグリカン / APC遺伝子 / βcatenin / βcateninシグナル / 心臓粘液腫 Less
  • Research Projects

    (6 results)
  • Research Products

    (39 results)
  • Co-Researchers

    (6 People)
  •  Elucidation of molecular mechanisms of occurrence of anaplastic thyroid cancer using gene mutation analysis and comprehensive gene expression analysisPrincipal Investigator

    • Principal Investigator
      伊藤 研一
    • Project Period (FY)
      2023 – 2025
    • Research Category
      Grant-in-Aid for Scientific Research (C)
    • Review Section
      Basic Section 55010:General surgery and pediatric surgery-related
    • Research Institution
      Shinshu University
  •  Elucidation of the molecular mechanism of development of anaplastic thyroid cancer using gene mutation analysis and comprehensive gene expression analysisPrincipal Investigator

    • Principal Investigator
      Ito Ken-ichi
    • Project Period (FY)
      2020 – 2022
    • Research Category
      Grant-in-Aid for Scientific Research (C)
    • Review Section
      Basic Section 55010:General surgery and pediatric surgery-related
    • Research Institution
      Shinshu University
  •  Elucidation of the molecular mechanism of anaplastic transformation by comprehensive gene expression analysis and development of novel therapeutic strategies for anaplastic thyroid cancerPrincipal Investigator

    • Principal Investigator
      Ito Ken-ichi
    • Project Period (FY)
      2017 – 2019
    • Research Category
      Grant-in-Aid for Scientific Research (C)
    • Research Field
      General surgery
    • Research Institution
      Shinshu University
  •  Analysis of mechanisms of function of EpCAM toward the development of molecular target for anaplastic thyroid cancerPrincipal Investigator

    • Principal Investigator
      ITO Ken-ichi
    • Project Period (FY)
      2013 – 2015
    • Research Category
      Grant-in-Aid for Scientific Research (C)
    • Research Field
      General surgery
    • Research Institution
      Shinshu University
  •  Analysis of predictive factors for chemotherapeutic response in breast cancer by using histoculture drug response assay and immunohistochemistry.Principal Investigator

    • Principal Investigator
      ITO Ken-ichi
    • Project Period (FY)
      2005 – 2006
    • Research Category
      Grant-in-Aid for Scientific Research (C)
    • Research Field
      General surgery
    • Research Institution
      Shinshu University
  •  Study on Tumor Characteristics of Cardiac Myxoma in Wnt Signal Transduction

    • Principal Investigator
      AMANO Jun
    • Project Period (FY)
      2004 – 2005
    • Research Category
      Grant-in-Aid for Scientific Research (C)
    • Research Field
      Thoracic surgery
    • Research Institution
      Shinshu University School of Medicine

All 2022 2020 2018 2017 2016 2015 2014 2013 2007 2006 2005 2004 Other

All Journal Article Presentation

  • [Journal Article] Surgical resection of the primary tumor prevents the undesirable locoregional condition and improves the quality of life in patients with anaplastic thyroid cancer2022

    • Author(s)
      2.Kanai T, Ito T, Morikawa H, Amitani M, Shimizu T, Ohno K, Ono M, Oba T, Maeno K, Ito K
    • Journal Title

      Surgery Today

      Volume: 52 Issue: 11 Pages: 1620-1626

    • DOI

      10.1007/s00595-022-02494-8

    • Peer Reviewed / Open Access
    • Data Source
      KAKENHI-PROJECT-20K08953
  • [Journal Article] Epidermal growth factor receptor activation confers resistance to lenvatinib in thyroid cancer cells2022

    • Author(s)
      Ohno Koichi、Shibata Tomohiro、Ito Ken‐ichi
    • Journal Title

      Cancer Science

      Volume: 113 Issue: 9 Pages: 3193-3210

    • DOI

      10.1111/cas.15465

    • Peer Reviewed / Open Access
    • Data Source
      KAKENHI-PROJECT-21K06641, KAKENHI-PROJECT-21KK0276, KAKENHI-PROJECT-20J00393, KAKENHI-PROJECT-20K08953
  • [Journal Article] Combination of two anti-tubulin agents, eribulin and paclitaxel, enhances anti-tumor effects on triple-negative breast cancer through mesenchymal-epithelial transition2018

    • Author(s)
      Oba Takaaki、Ito Ken-Ichi
    • Journal Title

      Oncotarget

      Volume: 9 Issue: 33 Pages: 22986-23002

    • DOI

      10.18632/oncotarget.25184

    • Peer Reviewed / Open Access
    • Data Source
      KAKENHI-PROJECT-17K10541
  • [Journal Article] Chylous leakage after axillary lymph node dissection in a patient with breast cancer2018

    • Author(s)
      Oba Takaaki、Ono Mayu、Iesato Asumi、Hanamura Toru、Watanabe Takayuki、Ito Tokiko、Kanai Toshiharu、Maeno Kazuma、Ito Ken-ichi
    • Journal Title

      The Breast Journal

      Volume: 24 Issue: 3 Pages: 438-440

    • DOI

      10.1111/tbj.12934

    • Peer Reviewed / Open Access / Int'l Joint Research
    • Data Source
      KAKENHI-PROJECT-16K10453, KAKENHI-PROJECT-17K10541
  • [Journal Article] 期待される新薬―分子標的治療薬の効果と副作用:小分子薬(3)レンバチニブ2018

    • Author(s)
      伊藤勅子、伊藤研一
    • Journal Title

      腫瘍内科

      Volume: 21 Pages: 675-682

    • Data Source
      KAKENHI-PROJECT-17K10541
  • [Journal Article] Increased Expression of Y-Box-Binding Protein-1 in Hind-Limb Muscles During Regeneration from Ischemic Injury in Mice2018

    • Author(s)
      Fuke Megumi、Narita Makoto、Wada Yuko、Seto Tatsuichiro、Okada Kenji、Nakayama Jun、Izumi Hiroto、Ito Ken-ichi
    • Journal Title

      Tohoku J. Exp. Med.

      Volume: 244 Issue: 1 Pages: 53-62

    • DOI

      10.1620/tjem.244.53

    • NAID

      130006316034

    • ISSN
      0040-8727, 1349-3329
    • Language
      English
    • Peer Reviewed / Open Access
    • Data Source
      KAKENHI-PROJECT-17K10541
  • [Journal Article] Lenvatinib (VEGFR阻害薬)の臨床試験と適正使用2018

    • Author(s)
      伊藤研一,清水忠史,相馬藍,竹腰大也,小野真由,大場崇旦,伊藤勅子,金井敏晴,前野一真
    • Journal Title

      腫瘍内科

      Volume: 22 Pages: 404-409

    • Data Source
      KAKENHI-PROJECT-17K10541
  • [Journal Article] PATZ1 knockdown enhances malignant phenotype in thyroid epithelial follicular cells and thyroid cancer cells.2017

    • Author(s)
      Iesato A, Nakamura T, Izumi H, Uehara T, Ito K
    • Journal Title

      Oncotarget

      Volume: 8 Issue: 47 Pages: 82754-82772

    • DOI

      10.18632/oncotarget.19787

    • Peer Reviewed / Open Access
    • Data Source
      KAKENHI-PROJECT-17K10541
  • [Journal Article] Lipid-rich carcinoma of the breast that is strongly positive for estrogen receptor: a case report and literature review2016

    • Author(s)
      Oba T, Ono M, Iesato A, Hanamura T, Watanabe T, Ito T, Kanai T, Maeno K, Ito K, Tateishi A, Yoshizawa A, Takayama F
    • Journal Title

      Onco Targets Ther

      Volume: 9 Pages: 1641-1646

    • DOI

      10.2147/ott.s88726

    • Peer Reviewed / Open Access
    • Data Source
      KAKENHI-PROJECT-25461976
  • [Journal Article] Coexpression of EpCAM, CD44 variant isoforms and Claudin-7 in anaplastic thyroid carcinoma2014

    • Author(s)
      Okada T, Nakamura T, Watanabe T, Onoda N, Asida A, Okuyama R, Ito K
    • Journal Title

      PLoS One

      Volume: 9 Issue: 4 Pages: 1-13

    • DOI

      10.1371/journal.pone.0094487

    • Peer Reviewed / Open Access
    • Data Source
      KAKENHI-PROJECT-23591615, KAKENHI-PROJECT-25461976, KAKENHI-PROJECT-25461992, KAKENHI-PROJECT-26461686
  • [Journal Article] 抗癌剤感受性試験と免疫組織染色を用いての乳癌抗癌剤感受性予測の試み2007

    • Author(s)
      伊藤研一, 藤森実, 天野純
    • Journal Title

      第5回日本臨床腫瘍学会学術集会プログラム抄録集

    • Data Source
      KAKENHI-PROJECT-17591325
  • [Journal Article] 免疫組織染色と抗癌剤感受性試験を用いた乳癌における化学療法効果予測の試み2007

    • Author(s)
      伊藤研一, 湯沢史帆, 前野一真 他
    • Journal Title

      第40回制癌剤適応研究会プログラム抄録集

    • Data Source
      KAKENHI-PROJECT-17591325
  • [Journal Article] 抗癌剤感受性試験を用いての乳癌における抗癌剤感受性予測因子の探索2007

    • Author(s)
      伊藤研一, 前野一真, 五味邦之, 他
    • Journal Title

      日本外科学会雑誌 108・臨増2

      Pages: 223-223

    • NAID

      110006330931

    • Description
      「研究成果報告書概要(和文)」より
    • Data Source
      KAKENHI-PROJECT-17591325
  • [Journal Article] 抗癌剤感受性試験を用いての乳癌における抗癌剤感受性予測因子の解析2006

    • Author(s)
      伊藤研一, 前野一真, 他
    • Journal Title

      日本癌治療学会誌 41・2

      Pages: 641-641

    • Description
      「研究成果報告書概要(和文)」より
    • Data Source
      KAKENHI-PROJECT-17591325
  • [Journal Article] 抗癌剤感受性試験を用いての乳癌における抗癌剤感受性予測因子の解析2006

    • Author(s)
      伊藤研一, 前野一真, 坂井威彦 他
    • Journal Title

      第65回日本癌学会学術総会記事

      Pages: 483-483

    • Data Source
      KAKENHI-PROJECT-17591325
  • [Journal Article] 抗癌剤感受性試験を用いての乳癌における抗癌剤感受性予測因子の解析2006

    • Author(s)
      伊藤研一, 前野一真, 坂井威彦, 他
    • Journal Title

      第65回日本癌学会学術総会記事

      Pages: 483-483

    • Description
      「研究成果報告書概要(和文)」より
    • Data Source
      KAKENHI-PROJECT-17591325
  • [Journal Article] 乳癌地y漏における抗癌剤感受性試験を用いたpersonalized medicineの試み2006

    • Author(s)
      伊藤研一, 前野一真, 坂井威彦 他
    • Journal Title

      第14回日本乳癌学界学術総会プログラム抄録集

      Pages: 333-333

    • Data Source
      KAKENHI-PROJECT-17591325
  • [Journal Article] 乳癌治療における抗癌剤感受性試験を用いたpersonalized medicineの試み2006

    • Author(s)
      伊藤研一, 前野一真, 坂井威彦, 他
    • Journal Title

      第14回日本乳癌学会学術総会プログラム抄録集

      Pages: 333-333

    • Description
      「研究成果報告書概要(和文)」より
    • Data Source
      KAKENHI-PROJECT-17591325
  • [Journal Article] Increased nuclear localization of transcription factor Y-box binding protein 1 accompanied by up-regulation of P-glycoprotein in breast cancer pretreated with paclitaxel.2005

    • Author(s)
      Fujita T, Ito K, Izumi H, et al.
    • Journal Title

      Clinical Cancer Research 11(24)

      Pages: 8837-8844

    • Description
      「研究成果報告書概要(欧文)」より
    • Data Source
      KAKENHI-PROJECT-17591325
  • [Journal Article] Increased nuclear localization of transcription factor Y-box binding protein l accompanied by up-regulation of P-glycoprotein in breast cancer pretreated with paclitaxel.2005

    • Author(s)
      Fujita T, Ito K, Izumi H, et al.
    • Journal Title

      Clinical Cancer Research 11・24

      Pages: 8837-8844

    • Description
      「研究成果報告書概要(和文)」より
    • Data Source
      KAKENHI-PROJECT-17591325
  • [Journal Article] Increased Nuclear Localization of Transcription Factor Y-Box Binding Protein 1 Accompanied by Up-Regulation of P-glycoprotein in Breast Cancer Pretreated with Paclitaxel2005

    • Author(s)
      Tomoyuki Fujita, Ken-ichi Ito, Hiroto Izumi, Morihiko Kimura, Muneaki Sano, Hiroshi Nakagomi, Kazuma Maeno, Yoshihisa Hama, Kiyoshi Shingu, Shin-ichi Tsuchiya, Kimitoshi Kohno, Minoru Fujimori
    • Journal Title

      Clinical Cancer Research 15・11

      Pages: 8837-8844

    • Data Source
      KAKENHI-PROJECT-17591325
  • [Journal Article] Stimulation of P19CL6 with multiple reagents induces pulsating particles in vivo.2005

    • Author(s)
      Ohtsu Y, Johkura K, Ito K, et al.
    • Journal Title

      Curr Med Res Opin 21・5

      Pages: 795-803

    • Description
      「研究成果報告書概要(和文)」より
    • Data Source
      KAKENHI-PROJECT-16591389
  • [Journal Article] Paclitaxelによる術前化学療法を施行した乳癌でのYB-1,P糖蛋白の発現の検討2005

    • Author(s)
      藤田知之, 伊藤研一, 他
    • Journal Title

      第13回日本乳癌学会総会プログラム抄録集

      Pages: 327-327

    • Description
      「研究成果報告書概要(和文)」より
    • Data Source
      KAKENHI-PROJECT-17591325
  • [Journal Article] Stimulation of P19CL6 with multiple reagents induces pulsating particles in vivo.2005

    • Author(s)
      Ohtsu Y, Johkura K, Ito K, et al.
    • Journal Title

      Curr Med Res Opin 21-5

      Pages: 795-803

    • Description
      「研究成果報告書概要(欧文)」より
    • Data Source
      KAKENHI-PROJECT-16591389
  • [Journal Article] Suppression of acute and chronic rejection by hepatocyte growth factor in a murine model of cardiac transplantation : induction of tolerance and prevention of cardiac allograft vasculopathy.2004

    • Author(s)
      Yamaura K, Ito K, et al.
    • Journal Title

      Circulation 110・12

      Pages: 467-470

    • Description
      「研究成果報告書概要(和文)」より
    • Data Source
      KAKENHI-PROJECT-16591389
  • [Journal Article] Suppression of acute and chronic rejection by hepatocyte growth factor in a murine model of cardiac transplantation : induction of tolerance and prevention of cardiac allograft vasculopathy2004

    • Author(s)
      Yamaura K, Ito K, et al.
    • Journal Title

      Circulation 110-12

      Pages: 467-470

    • Description
      「研究成果報告書概要(欧文)」より
    • Data Source
      KAKENHI-PROJECT-16591389
  • [Presentation] The mechanisms involved in the resistance of estrogen receptor-positive breast cancer cells to palbociclib are multiple and change over time2022

    • Author(s)
      Ono M, Oba T, Shibata T, Ito K
    • Organizer
      2.6th International Anatomical Sciences and Cell Biology Conference 2022
    • Invited / Int'l Joint Research
    • Data Source
      KAKENHI-PROJECT-20K08953
  • [Presentation] Epidermal growth factor receptor activation confers resistance to lenvatinib in thyroid cancer cells2022

    • Author(s)
      Ohno K., Shibata T, Ito K
    • Organizer
      3.91st Annual Meeting of the American Thyroid Association
    • Int'l Joint Research
    • Data Source
      KAKENHI-PROJECT-20K08953
  • [Presentation] 甲状腺癌培養細胞株でのチロシンキナーゼ阻害薬作用機序の違いの解析2020

    • Author(s)
      伊藤研一、千野辰徳、大野晃一、小野真由、伊藤勅子、金井敏晴、前野一真
    • Organizer
      第32回日本内分泌外科学会総会
    • Data Source
      KAKENHI-PROJECT-17K10541
  • [Presentation] 甲状腺癌培養細胞株を用いた分子標的薬耐性機序の解析2018

    • Author(s)
      伊藤研一,金井祐起子,清水忠文,相馬藍,竹腰大也, 大場崇旦,伊藤勅子,金井敏晴,前野一真
    • Organizer
      第 30 回日本内分泌外科学会総会
    • Data Source
      KAKENHI-PROJECT-17K10541
  • [Presentation] 甲状腺癌の発癌、進展における 転写調節因子PATZ1発現の意義2016

    • Author(s)
      家里 明日美,小野真由,大場崇旦,福島優子 伊藤勅子,金井敏晴,前野一真,伊藤研一
    • Organizer
      第28回日本内分泌外科学会総会
    • Place of Presentation
      ロイヤルホール横浜(横浜市中区)
    • Year and Date
      2016-05-26
    • Data Source
      KAKENHI-PROJECT-25461976
  • [Presentation] 甲状腺癌における転写因子PATZ1発現の意義2015

    • Author(s)
      家里明日美,小野真由,大場崇旦,花村徹,伊藤勅子,金井敏晴,前野一真,伊藤研一
    • Organizer
      第115回日本外科学会定期学術集会
    • Place of Presentation
      名古屋国際会議場(名古屋市熱田区)
    • Year and Date
      2015-04-16
    • Data Source
      KAKENHI-PROJECT-25461976
  • [Presentation] 甲状腺癌の発癌と進展における転写調節因子PATZ1発現の関与2015

    • Author(s)
      家里明日美,小野真由,大場崇旦,福島優子,伊藤勅子, 金井敏晴,前野一真,伊藤研一
    • Organizer
      第74回日本癌学会学術総会
    • Place of Presentation
      名古屋国際会議場(名古屋市熱田区)
    • Year and Date
      2015-10-08
    • Data Source
      KAKENHI-PROJECT-25461976
  • [Presentation] 甲状腺未分化癌におけるEpCAMとその関連因子CD44,claudin-7の発現とALDH1酵素活性2014

    • Author(s)
      岡田敏宏,大場崇旦,家里明日美,花村徹,渡邉隆之,伊藤勅子,金井敏晴,前野一真,伊藤研一,小野田尚佳
    • Organizer
      第26回日本内分泌外科学会総会
    • Place of Presentation
      名古屋市
    • Data Source
      KAKENHI-PROJECT-25461976
  • [Presentation] 甲状腺未分化癌におけるCD44,EpCAMの発現とALDH1酵素活性2013

    • Author(s)
      ② 岡田敏宏,大場崇旦,家里明日美,花村徹,渡邉隆之,金井敏晴,前野一真,伊藤研一,天野純, 小野田尚佳
    • Organizer
      第46回日本甲状腺外科学会学術集会
    • Place of Presentation
      名古屋市
    • Data Source
      KAKENHI-PROJECT-25461976
  • [Presentation] 甲状腺癌におけるCD44の発現とALDH1酵素活性2013

    • Author(s)
      岡田敏宏,家里明日美,花村徹,村松沙織,村山幸一,渡邉隆之,金井敏晴,前野一真,望月靖弘, 伊藤研一,天野純,小野田尚佳
    • Organizer
      第113回日本外科学会定期学術集会
    • Place of Presentation
      福岡市
    • Data Source
      KAKENHI-PROJECT-25461976
  • [Presentation] 甲状腺未分化癌におけるCD44, EpCAMの発現2013

    • Author(s)
      岡田敏宏,伊藤研一,天野純,小野田尚佳
    • Organizer
      第22回日本がん転移学会学術集会
    • Place of Presentation
      松本市
    • Data Source
      KAKENHI-PROJECT-25461976
  • [Presentation] Association of CD44 expression and ALDH1 activity in thyroid cancer.2013

    • Author(s)
      Toshihiro Okada, Ken-ichi Ito, Jun Amano, Naoyoshi Onoda
    • Organizer
      AACR Annual meeting 2013
    • Place of Presentation
      Washington DC, USA
    • Data Source
      KAKENHI-PROJECT-25461976
  • [Presentation] 甲状腺未分化癌の分子標的開発に向けたEpCAMの機能解析

    • Author(s)
      中村輝郎,上条しのぶ,伊藤研一
    • Organizer
      第73回日本癌学会学術総会
    • Place of Presentation
      横浜(パシフィコ横浜)
    • Year and Date
      2014-09-25 – 2014-09-27
    • Data Source
      KAKENHI-PROJECT-25461976
  • 1.  AMANO Jun (20138283)
    # of Collaborated Projects: 1 results
    # of Collaborated Products: 0 results
  • 2.  NAKAYAMA Jun (10221459)
    # of Collaborated Projects: 1 results
    # of Collaborated Products: 0 results
  • 3.  FUJIMORI Minoru (00262725)
    # of Collaborated Projects: 1 results
    # of Collaborated Products: 0 results
  • 4.  柴田 智博
    # of Collaborated Projects: 0 results
    # of Collaborated Products: 1 results
  • 5.  伊藤 勅子
    # of Collaborated Projects: 0 results
    # of Collaborated Products: 1 results
  • 6.  奥山 隆平
    # of Collaborated Projects: 0 results
    # of Collaborated Products: 1 results

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