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NAKAJIMA Masahiro  中島 正宏

ORCIDConnect your ORCID iD *help
Researcher Number 10338692
Other IDs
Affiliation (based on the past Project Information) *help 2020 – 2022: 国立研究開発法人理化学研究所, 生命医科学研究センター, 研究員
2001 – 2002: 帝京大学, 薬学部, 助手
Review Section/Research Field
Principal Investigator
Basic Section 56020:Orthopedics-related
Except Principal Investigator
Environmental pharmacy
Keywords
Principal Investigator
脊椎後縦靭帯骨化症 / CCDC91 / 疾患感受性遺伝子 / OPLL / 後縦靭帯骨化症
Except Principal Investigator
cAMP / CYTOCHALASINB / CYTOSKELETON / VITAMIN D3 / OSTEOCALCIN … More / ALKALINE PHOSPHATASE / OSTEOBLASTS / OUASI-MICROGRAVITY / 高重力環境 / 低重力環境 / 1α、25-(OH)_2D_3 / クメステロール類縁体(KCA-098) / クリノスタット培養 / 微小重力環境 / サイトカラシンB / 細胞質骨格系 / ビタミンD_3 / オステオカルシン / アルカリホスファターゼ / 骨芽細胞 / 擬似微小重力 Less
  • Research Projects

    (2 results)
  • Research Products

    (6 results)
  • Co-Researchers

    (2 People)
  •  Identification of susceptibility genes for ossification of the posterior longitudinal ligament of the spinePrincipal Investigator

    • Principal Investigator
      NAKAJIMA Masahiro
    • Project Period (FY)
      2020 – 2022
    • Research Category
      Grant-in-Aid for Scientific Research (B)
    • Review Section
      Basic Section 56020:Orthopedics-related
    • Research Institution
      Institute of Physical and Chemical Research
  •  The changes of bone metabolism induced by quasi-microgravity and its recovery by the bone-metabolizing agents.

    • Principal Investigator
      KAWASHIMA Kohtaro
    • Project Period (FY)
      2000 – 2002
    • Research Category
      Grant-in-Aid for Scientific Research (C)
    • Research Field
      Environmental pharmacy
    • Research Institution
      TEIKYO UNIVERSITY

All 2023 2022 2021 2020

All Journal Article Presentation

  • [Journal Article] A novel CCDC91 isoform associated with ossification of the posterior longitudinal ligament of the spine works as a non-coding RNA to regulate osteogenic genes2023

    • Author(s)
      Nakajima Masahiro、Koido Masaru、Guo Long、Terao Chikashi、Ikegawa Shiro
    • Journal Title

      The American Journal of Human Genetics

      Volume: 110 Issue: 4 Pages: 638-647

    • DOI

      10.1016/j.ajhg.2023.03.004

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-20H03811, KAKENHI-PROJECT-20K15773, KAKENHI-PROJECT-20H00462, KAKENHI-PROJECT-23K24466
  • [Journal Article] Identification of a Functional Susceptibility Variant for Adolescent Idiopathic Scoliosis that Upregulates Early Growth Response 1 (EGR1)‐Mediated <scp> <i>UNCX</i> </scp> Expression2022

    • Author(s)
      Yonezawa Yoshiro、Guo Long、Kakinuma Hisaya、Otomo Nao、Yoshino Soichiro、Takeda Kazuki、Nakajima Masahiro、他42名
    • Journal Title

      Journal of Bone and Mineral Research

      Volume: 38 Issue: 1 Pages: 144-153

    • DOI

      10.1002/jbmr.4738

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-20H03811, KAKENHI-PROJECT-20K09416, KAKENHI-PROJECT-20K09451, KAKENHI-PROJECT-23K27724
  • [Journal Article] Genetic insights into ossification of the posterior longitudinal ligament of the spine2022

    • Author(s)
      Koike Yoshinao、Takahata Masahiko、Nakajima Masahiro、他48名
    • Journal Title

      medRxiv

      Volume: -

    • DOI

      10.1101/2022.06.16.22276152

    • Open Access
    • Data Source
      KAKENHI-PROJECT-20H03811
  • [Journal Article] CDC5L promotes early chondrocyte differentiation and proliferation by modulating pre-mRNA splicing of SOX9, COL2A1, and WEE12021

    • Author(s)
      Jokoji Go、Maeda Shingo、Oishi Kazuki、Ijuin Toshiro、Nakajima Masahiro、Tawaratsumida Hiroki、Kawamura Ichiro、Tominaga Hiroyuki、Taketomi Eiji、Ikegawa Shiro、Taniguchi Noboru
    • Journal Title

      Journal of Biological Chemistry

      Volume: 297 Issue: 2 Pages: 100994-100994

    • DOI

      10.1016/j.jbc.2021.100994

    • Peer Reviewed / Open Access
    • Data Source
      KAKENHI-PROJECT-20H03811, KAKENHI-PROJECT-20K09482
  • [Presentation] 脊椎後縦靭帯骨化症原因候補遺伝子CDC5Lは骨芽細胞分化を抑制し、初期軟骨細胞分化を促進する2021

    • Author(s)
      城光寺豪, 前田真吾, 中島正宏, 河村一郎, 八尋雄平, 冨永博之, 武冨榮二, 池川志郎, 谷口昇
    • Organizer
      第33回 日本軟骨代謝学会
    • Data Source
      KAKENHI-PROJECT-20H03811
  • [Presentation] 脊椎後縦靱帯骨化症原因候補遺伝子CDC5Lは初期軟骨細胞分化を促進する2020

    • Author(s)
      城光寺豪, 前田真吾, 中島正宏, 河村一郎, 八尋雄平, 冨永博之, 武冨榮二, 池川志郎, 谷口昇
    • Organizer
      第35回 日本整形外科学会基礎学術集会
    • Data Source
      KAKENHI-PROJECT-20H03811
  • 1.  KAWASHIMA Kohtaro (20124993)
    # of Collaborated Projects: 1 results
    # of Collaborated Products: 0 results
  • 2.  根岸 洋一 (50286978)
    # of Collaborated Projects: 1 results
    # of Collaborated Products: 0 results

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