Masuda Akio 増田章男

… Alternative Names

MASUDA Akio 増田章男

増田章男マスダアキオ

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Researcher Number	10343203
Other IDs
Affiliation (Current)	2025: 愛知県医療療育総合センター発達障害研究所, 細胞病態研究部, 部長
Affiliation (based on the past Project Information) *help	2025: 愛知県医療療育総合センター発達障害研究所, 細胞病態研究部, 部長 2016 – 2024: 名古屋大学, 医学系研究科, 准教授 2012 – 2015: 名古屋大学, 医学(系)研究科(研究院), 准教授 2014: 名古屋大学, 大学院医学系研究科, 准教授 2010 – 2011: Nagoya University, 医学系研究科, 助教 … More 2008 – 2011: Nagoya University, 大学院・医学系研究科, 助教 2007: 名古屋大学, 大学院・医学系・研究科, 助教 2005 – 2006: 名古屋大学, 大学院医学系研究科, 助手 2005: 名古屋大学, 大学院・医学系研究科, 助手 2002 – 2003: 名古屋大学, 大学院・医学系研究科, 助手 Less
Review Section/Research Field	Principal Investigator Basic Section 43010:Molecular biology-related / Medium-sized Section 45:Biology at organismal to population levels and anthropology, and related fields / Basic Section 44010:Cell biology-related / Medium-sized Section 43:Biology at molecular to cellular levels, and related fields / Nerve anatomy/Neuropathology / Neurophysiology and muscle physiology / 膠原病・アレルギー・感染症内科学 / Neurochemistry/Neuropharmacology / Immunology Except Principal Investigator Neurology … More / Basic Section 51030:Pathophysiologic neuroscience-related / Cell biology / Basic Section 52020:Neurology-related / Basic Section 52050:Embryonic medicine and pediatrics-related / Hygiene Less
Keywords	Principal Investigator RNA代謝 / スプライシング / RNA結合タンパク / 相分離 / エクソン / CLIP / RNA-タンパク相互作用 / tRIP / 天然変性領域 / IDR … More / mRNA / RNAP II / RNA-蛋白相互作用 / FUS / RNA / 核 / ノックアウト / 進化 / 神経変性疾患 / 液ー液相分離 / クロマチン分画 / MATR3 / U1 snRNP / 転写制御 / SRSF3 / RNA修飾 / 次世代シークエンサー / ALS / ポリアデニル化 / CLIP法 / レーザーマイクロダイセクション / Agrin / RNA-seq / 筋分化 / 神経筋接合部 / RODI / splicing / ROD1 / 神経科学 / 遺伝子 / MS2 / AChR / 筋無力症 / HnRNP-H / PTBP1 / アポトーシス / 3 / BaF / cDNAライブラリー / IL-15 / マスト細胞 … More Except Principal Investigator 先天性筋無力症候群 / 神経筋接合部 / 細胞分裂 / スプライシング / アセチルコリン受容体 / 神経科学 / 遺伝子 / スプライシング異常 / PSP / ALS / 核酸医薬 / RNA結合タンパク質 / FTLDスペクトラム / 前頭側頭葉変性症 / tau / RNP / SFPQ / FUS / FTLD / iPS細胞 / MERS－異常言動スペクトラム / 可逆性脳梁病変 / 遺伝子解析 / 異常言動 / MERS / MYRF / アルギニン / UBAP2L / メチル化 / アルギニンメチル化 / mRNA splicing / congenital myasthenic syndromes / 脳神経疾患 / 脳・神経 / 蛋白質 / mRNAスプライシング / ＲＮＡ / ＳＮＷ１ / ＣＤＣ５Ｌ / ＢＣＡＳ２ / アポトーシス / 細胞周期 / RNA / ColQ / Wnt / LRP4 / LGR5 / RSPO2 / hnRNP LL / hnRNP L / スプライシングトランス因子 / Collagen Q / 終板アセチルコリンエステラーゼ欠損症 / protein-anchoring therapy / パーキンソン病 / ヒドロキシラジカル / 酸化ストレス / 活性酸素 / 分子状水素 / 住環境 / マイクロアレイ / ゲノム / タンニン酸 Less

転写から翻訳に向けてmRNAが走る核内基本構造の同定と機能解明Principal Investigator
- Principal Investigator
  
  増田章男
- Project Period (FY)
  2025 – 2027
- Research Category
  
  Grant-in-Aid for Scientific Research (B)
- Review Section
  
  Basic Section 43010:Molecular biology-related
- Research Institution
  Institute for Developmental Research Aichi Developmental Disability Center
辺縁エクソン群に宿る生物進化・機能獲得の鍵Principal Investigator
- Principal Investigator
  
  増田章男
- Project Period (FY)
  2024 – 2026
- Research Category
  
  Grant-in-Aid for Challenging Research (Exploratory)
- Review Section
  
  Medium-sized Section 45:Biology at organismal to population levels and anthropology, and related fields
- Research Institution
  Nagoya University
Investigation of the molecular formations and the pathomechanisms of the neuromuscular junction
- Principal Investigator
  
  大野欽司
- Project Period (FY)
  2023 – 2025
- Research Category
  
  Grant-in-Aid for Scientific Research (B)
- Review Section
  
  Basic Section 51030:Pathophysiologic neuroscience-related
- Research Institution
  Nagoya University of Arts and Sciences
  Nagoya University
in situ cDNA増幅による超高感度 RNA-蛋白相互作用解析法の開発Principal Investigator
- Principal Investigator
  
  増田章男
- Project Period (FY)
  2022 – 2024
- Research Category
  
  Grant-in-Aid for Challenging Research (Exploratory)
- Review Section
  
  Medium-sized Section 43:Biology at molecular to cellular levels, and related fields
- Research Institution
  Nagoya University
天然変性領域 (IDR) 形成を支えるスプライシング機構から俯瞰する相分離現象Principal Investigator
- Principal Investigator
  
  増田章男
- Project Period (FY)
  2021 – 2024
- Research Category
  
  Grant-in-Aid for Scientific Research (B)
- Review Section
  
  Basic Section 44010:Cell biology-related
- Research Institution
  Nagoya University
FTLDスペクトラムにおける核内RNP複合体の機能変化に基づく核酸医療の開発
- Principal Investigator
  
  石垣診祐
- Project Period (FY)
  2021 – 2024
- Research Category
  
  Grant-in-Aid for Scientific Research (B)
- Review Section
  
  Basic Section 52020:Neurology-related
- Research Institution
  Shiga University of Medical Science
Elucidation of molecular mechanisms of neuromuscular junction formations in physiology and pathology
- Principal Investigator
  
  Ohno Kinji
- Project Period (FY)
  2020 – 2022
- Research Category
  
  Grant-in-Aid for Scientific Research (B)
- Review Section
  
  Basic Section 51030:Pathophysiologic neuroscience-related
- Research Institution
  Nagoya University
Identification of the role of transcription termination and polyadenylation in ALS using multiple high-throughput sequencing analysisPrincipal Investigator
- Principal Investigator
  
  Masuda Akio
- Project Period (FY)
  2018 – 2021
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Review Section
  
  Basic Section 43010:Molecular biology-related
- Research Institution
  Nagoya University
Analysis of the molecular basis of MERS-delirious behavior spectrum
- Principal Investigator
  
  Okumura Akihisa
- Project Period (FY)
  2018 – 2022
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Review Section
  
  Basic Section 52050:Embryonic medicine and pediatrics-related
- Research Institution
  Aichi Medical University
Identification of the role of transcription termination and polyadenylation in the pathogenesis of ALS using multiple high-throughput sequencing analysesPrincipal Investigator
- Principal Investigator
  
  Masuda Akio
- Project Period (FY)
  2015 – 2018
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Research Field
  
  Nerve anatomy/Neuropathology
- Research Institution
  Nagoya University
Regulation of cell division by arginine methylation and translation
- Principal Investigator
  
  Senga Takeshi
- Project Period (FY)
  2015 – 2016
- Research Category
  
  Grant-in-Aid for Challenging Exploratory Research
- Research Field
  
  Cell biology
- Research Institution
  Nagoya University
RNA splicing mediated cell cycle progression
- Principal Investigator
  
  SENGA Takeshi
- Project Period (FY)
  2013 – 2014
- Research Category
  
  Grant-in-Aid for Challenging Exploratory Research
- Research Field
  
  Cell biology
- Research Institution
  Nagoya University
Molecular bases and their regulations of mRNA aberrations in neuromuscular transmission defects and other muscular diseases
- Principal Investigator
  
  OHNO Kinji
- Project Period (FY)
  2012 – 2014
- Research Category
  
  Grant-in-Aid for Scientific Research (B)
- Research Field
  
  Neurology
- Research Institution
  Nagoya University
Identification of specific splicing regulation at neuromuscular junctionsPrincipal Investigator
- Principal Investigator
  
  Masuda Akio
- Project Period (FY)
  2012 – 2015
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Research Field
  
  Neurophysiology and muscle physiology
- Research Institution
  Nagoya University
Analysis of mRNA metabolisms and therapeutic interventions for defects in neuromuscular signal transduction
- Principal Investigator
  
  OHNO Kinji
- Project Period (FY)
  2009 – 2011
- Research Category
  
  Grant-in-Aid for Scientific Research (B)
- Research Field
  
  Neurology
- Research Institution
  Nagoya University
New approach for health maintenanceand disease control by modification of inhaled air composition
- Principal Investigator
  
  ICHIHARA Masatoshi
- Project Period (FY)
  2008 – 2010
- Research Category
  
  Grant-in-Aid for Scientific Research on Innovative Areas (Research a proposed research project)
- Research Field
  
  Hygiene
- Research Institution
  Chubu University
Role of ROD1 in the pathogenesis of allergic inflammationPrincipal Investigator
- Principal Investigator
  
  MASUDA Aklo
- Project Period (FY)
  2008 – 2010
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Research Field
  
  膠原病・アレルギー・感染症内科学
- Research Institution
  Nagoya University
Molecular bases and their regulations of mRNA aberrations in neuromuscular transmission defects and other muscular diseases
- Principal Investigator
  
  OHNO Kinji
- Project Period (FY)
  2007 – 2008
- Research Category
  
  Grant-in-Aid for Scientific Research (B)
- Research Field
  
  Neurology
- Research Institution
  Nagoya University
先天性筋無力症におけるアセチルコリンレセプターαのsplicing異常の解析Principal Investigator
- Principal Investigator
  
  増田章男
- Project Period (FY)
  2005 – 2006
- Research Category
  
  Grant-in-Aid for Young Scientists (B)
- Research Field
  
  Neurochemistry/Neuropharmacology
- Research Institution
  Nagoya University
Molecular pathomechanisms of congenital defects of neuromuscular transmission
- Principal Investigator
  
  OHNO Kinji
- Project Period (FY)
  2005 – 2006
- Research Category
  
  Grant-in-Aid for Scientific Research (B)
- Research Field
  
  Neurology
- Research Institution
  Nagoya University
マスト細胞におけるIL-15レセプターの解析Principal Investigator
- Principal Investigator
  
  増田章男
- Project Period (FY)
  2002 – 2003
- Research Category
  
  Grant-in-Aid for Young Scientists (B)
- Research Field
  
  Immunology
- Research Institution
  Nagoya University

[Book] "Neurodegeneration-associated RNA-binding protein, FUS, regulates mRNA length" in Atlas of Science. Ed. by Lynn C Yeoman. http://atlasofscience.org/neurodegeneration-associated-rna-binding-protein-fus-regulates-mrna-length/2016
- Author(s)
  Akio Masuda. Ohno, K.
- Publisher
  AoS Nordic AB, Stockholm
- Data Source
  KAKENHI-PROJECT-15K06755
[Book] Neurodegeneration-associated RNA-binding protein, FUS, regulates mRNA length2016
- Author(s)
  Masuda, A. Ohno, K.
- Total Pages
  1
- Publisher
  ATLAS of Science
- Data Source
  KAKENHI-PROJECT-15K06755
[Book] Chapter 2: Intronic and exonic nucleotide variations that affect RNA splicing in humans. Genomics I - Humans, Animals and Plants.2013
- Author(s)
  Ohe K, Masuda A, Ohno K.
- Total Pages
  344
- Publisher
  iConcept Press, Hong Kong
- Data Source
  KAKENHI-PROJECT-24390221
[Book] RNA pathologies in neurological disorders. Neurochemical Mechanisms in Disease, Advances in Neurobiology2011
- Author(s)
  Ohno K, Masuda A
- Publisher
  Springer, New York
- Data Source
  KAKENHI-PROJECT-21390266
[Book] RNA pathologies in neurological disorders. Neurochemical Mechanisms in Disease, Advances in Neurobiology(Ed by Abel Lajtha)2011
- Author(s)
  Ohno K, Masuda A
- Publisher
  Springer, New York
- Data Source
  KAKENHI-PROJECT-21390266
[Journal Article] Splicing regulation of GFPT1 muscle-specific isoform and its roles in glucose metabolisms and neuromuscular junction2023
- Author(s)
  Farshadyeganeh Paniz、Nazim Mohammad、Zhang Ruchen、Ohkawara Bisei、Nakajima Kazuki、Rahman Mohammad Alinoor、Nasrin Farhana、Ito Mikako、Takeda Jun-ichi、Ohe Kenji、Miyasaka Yuki、Ohno Tamio、Masuda Akio、Ohno Kinji
- Journal Title
  
  iScience
  
  Volume: 26 Issue: 10 Pages: 107746-107746
- DOI
  10.1016/j.isci.2023.107746
- Peer Reviewed / Open Access / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-22K19269, KAKENHI-PROJECT-23K06412, KAKENHI-PROJECT-20K06925, KAKENHI-PROJECT-21K08266, KAKENHI-PROJECT-23K21309, KAKENHI-PROJECT-21H04815, KAKENHI-PROJECT-23K27485
[Journal Article] FexSplice: A LightGBM-Based Model for Predicting the Splicing Effect of a Single Nucleotide Variant Affecting the First Nucleotide G of an Exon2023
- Author(s)
  Joudaki Atefeh、Takeda Jun-ichi、Masuda Akio、Ode Rikumo、Fujiwara Koichi、Ohno Kinji
- Journal Title
  
  Genes
  
  Volume: 14 Issue: 9 Pages: 1765-1765
- DOI
  10.3390/genes14091765
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-22K19269, KAKENHI-PROJECT-23K21309, KAKENHI-PROJECT-21H04815, KAKENHI-PROJECT-23K27485
[Journal Article] Neural Isoforms of Agrin Are Generated by Reduced PTBP1-RNA Interaction Network Spanning the Neuron-Specific Splicing Regions in AGRN2023
- Author(s)
  Bushra Samira、Lin Ying-Ni、Joudaki Atefeh、Ito Mikako、Ohkawara Bisei、Ohno Kinji、Masuda Akio
- Journal Title
  
  International Journal of Molecular Sciences
  
  Volume: 24 Issue: 8 Pages: 7420-7420
- DOI
  10.3390/ijms24087420
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-20H03561, KAKENHI-PROJECT-22K19269, KAKENHI-PROJECT-23K06412, KAKENHI-PROJECT-20K06925, KAKENHI-PROJECT-21K06392, KAKENHI-PROJECT-23K21309, KAKENHI-PROJECT-22H04925, KAKENHI-PROJECT-21H04815, KAKENHI-PROJECT-23K27485
[Journal Article] tRIP-seq 法による RNA 結合タンパク標的部位のトランスクリプトームワイド検出2022
- Author(s)
  増田章男、河地利彦
- Journal Title
  
  細胞
  
  Volume: 54 Pages: 55-58
- Data Source
  KAKENHI-PROJECT-22K19269
[Journal Article] tRIP-seq 法による RNA 結合タンパク標的部位のトランスクリプトームワイド検出2022
- Author(s)
  増田章男、河地利彦
- Journal Title
  
  細胞
  
  Volume: 54 Pages: 55-58
- Data Source
  KAKENHI-PROJECT-23K21309
[Journal Article] Liquid–liquid phase separation of transcription factors are sustained by large exons in vertebrates2022
- Author(s)
  増田章男、河地利彦
- Journal Title
  
  生化学
  
  Volume: 94 Issue: 5 Pages: 706-710
- DOI
  10.14952/SEIKAGAKU.2022.940706
- ISSN
  0037-1017
- Year and Date
  2022-10-25
- Language
  Japanese
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-22K19269, KAKENHI-PROJECT-23K21309
[Journal Article] Extremely low-frequency pulses of faint magnetic field induce mitophagy to rejuvenate mitochondria2022
- Author(s)
  Toda Takuro、Ito Mikako、Takeda Jun-ichi、Masuda Akio、Mino Hiroyuki、Hattori Nobutaka、Mohri Kaneo、Ohno Kinji
- Journal Title
  
  Communications Biology
  
  Volume: 5 Issue: 1 Pages: 453-453
- DOI
  10.1038/s42003-022-03389-7
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-20K06925, KAKENHI-PROJECT-22K19269, KAKENHI-PROJECT-21H04815, KAKENHI-PROJECT-23K21309
[Journal Article] Meclozine ameliorates skeletal muscle pathology and increases muscle forces in mdx mice2022
- Author(s)
  Kawamura Yusuke、Hida Tetsuro、Ohkawara Bisei、Matsushita Masaki、Kobayashi Takeshi、Ishizuka Shinya、Hiraiwa Hideki、Tanaka Satoshi、Tsushima Mikito、Nakashima Hiroaki、Ito Kenyu、Imagama Shiro、Ito Mikako、Masuda Akio、Ishiguro Naoki、Ohno Kinji
- Journal Title
  
  Biochemical and Biophysical Research Communications
  
  Volume: 592 Pages: 87-92
- DOI
  10.1016/j.bbrc.2022.01.003
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-18K06058, KAKENHI-PROJECT-18K06483, KAKENHI-PROJECT-19K22802, KAKENHI-PROJECT-21K06149, KAKENHI-PROJECT-21K06392, KAKENHI-PROJECT-22K19269, KAKENHI-PROJECT-20H03561, KAKENHI-PROJECT-21H04815, KAKENHI-PROJECT-23K21309
[Journal Article] A pilot study of serum free carnitine levels in hospitalized febrile children.2021
- Author(s)
  Okumura A, Muto T, Nakamura N, Masuda Y, Kodama S.
- Journal Title
  
  Pediatr Int.
  
  Volume: 63 Issue: 1 Pages: 102-103
- DOI
  10.1111/ped.14360
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-18K07890, KAKENHI-PROJECT-21K07810
[Journal Article] Regulated splicing of large exons is linked to phase‐separation of vertebrate transcription factors2021
- Author(s)
  Kawachi Toshihiko、Masuda Akio、Yamashita Yoshihiro、Takeda Jun‐ichi、Ohkawara Bisei、Ito Mikako、Ohno Kinji
- Journal Title
  
  The EMBO Journal
  
  Volume: 40 Issue: 22
- DOI
  10.15252/embj.2020107485
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-18K06058, KAKENHI-PROJECT-18K06483, KAKENHI-PROJECT-19K22802, KAKENHI-PROJECT-20K06925, KAKENHI-PROJECT-21K06392, KAKENHI-PROJECT-16H06279, KAKENHI-PROJECT-21H04815, KAKENHI-PROJECT-20H03561
[Journal Article] Screening of signaling pathways for agrin-induced AChR clustering in C2C12 myotubes2021
- Author(s)
  Noto K, Ohkawara B, Ishii H, Ito M, Masuda A, Hirata H, Ohno K.
- Journal Title
  
  Genes Cells
  
  Volume: -
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-20H03561
[Journal Article] Usefulness of Q-Probe PCR in Detecting Macrolide-Resistant <i>Mycoplasma pneumoniae</i> Infection in Children2021
- Author(s)
  Muto T, Nakamura N, Masuda Y, Numoto S, Kodama S, Miyamoto R, Hayakawa T, Mori H, Iwayama H, Kurahashi H, Agata H, Okumura
- Journal Title
  
  Jpn J Infect Dis
  
  Volume: 75 Issue: 1 Pages: 89-91
- DOI
  10.7883/yoken.JJID.2021.003
- NAID
  130008143946
- ISSN
  1344-6304, 1884-2836
- Year and Date
  2021-01-31
- Language
  English
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-18K07890
[Journal Article] tRIP-seq法を用いた微量検体からのRNA修飾部位検出2021
- Author(s)
  増田章男、河地利彦、大野欽司
- Journal Title
  
  細胞
  
  Volume: 53 Pages: 50-52
- NAID
  40022799109
- Data Source
  KAKENHI-PROJECT-18K06058
[Journal Article] Rapidly Growing Protein-Centric Technologies to Extensively Identify Protein?RNA Interactions: Application to the Analysis of Co-Transcriptional RNA Processing2021
- Author(s)
  Masuda Akio、Kawachi Toshihiko、Ohno Kinji
- Journal Title
  
  International Journal of Molecular Sciences
  
  Volume: 22 Issue: 10 Pages: 5312-5312
- DOI
  10.3390/ijms22105312
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-18K06058, KAKENHI-PROJECT-21H04815, KAKENHI-PROJECT-20H03561
[Journal Article] Zonisamide upregulates neuregulin-1 expression and enhances acetylcholine receptor clustering at the in vitro neuromuscular junction2021
- Author(s)
  Inoue Taro、Ohkawara Bisei、Bushra Samira、Kanbara Shunsuke、Nakashima Hiroaki、Koshimizu Hiroyuki、Tomita Hiroyuki、Ito Mikako、Masuda Akio、Ishiguro Naoki、Imagama Shiro、Ohno Kinji
- Journal Title
  
  Neuropharmacology
  
  Volume: 195 Pages: 108637-108637
- DOI
  10.1016/j.neuropharm.2021.108637
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-18K06058, KAKENHI-PROJECT-18K06483, KAKENHI-PROJECT-19K22802, KAKENHI-PROJECT-21K06392, KAKENHI-PROJECT-21H04815, KAKENHI-PROJECT-20H03561
[Journal Article] tRIP-seq Reveals Repression of Premature Polyadenylation by Co-Transcriptional FUS-U1 snRNP Assembly2020
- Author(s)
  Akio Masuda, Toshihiko Kawachi, Jun-Ichi Takeda, Bisei Ohkawara, Mikako Ito, Kinji Ohno
- Journal Title
  
  EMBO Rep.
  
  Volume: - Issue: 5
- DOI
  10.15252/embr.201949890
- NAID
  120006884959
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-17K07094, KAKENHI-PROJECT-18K06058, KAKENHI-PROJECT-18K06483, KAKENHI-PROJECT-19K22802, KAKENHI-PROJECT-16H06279, KAKENHI-PROJECT-20K06925, KAKENHI-PROJECT-20H03561, KAKENHI-PROJECT-18K14684
[Journal Article] Gene Expression Profile at the Motor Endplate of the Neuromuscular Junction of Fast-Twitch Muscle2020
- Author(s)
  Huang Kun、Li Jin、Ito Mikako、Takeda Jun-Ichi、Ohkawara Bisei、Ogi Tomoo、Masuda Akio、Ohno Kinji
- Journal Title
  
  Frontiers in Molecular Neuroscience
  
  Volume: 13 Pages: 154-154
- DOI
  10.3389/fnmol.2020.00154
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-18K06058, KAKENHI-PROJECT-18K06483, KAKENHI-PROJECT-20K06925, KAKENHI-PROJECT-19K22802, KAKENHI-PROJECT-20H03561, KAKENHI-PROJECT-17K07094, KAKENHI-PROJECT-18K14684
[Journal Article] Zonisamide ameliorates neuropathic pain partly by suppressing microglial activation in the spinal cord in a mouse model2020
- Author(s)
  Koshimizu Hiroyuki、Ohkawara Bisei、Nakashima Hiroaki、Ota Kyotaro、Kanbara Shunsuke、Inoue Taro、Tomita Hiroyuki、Sayo Akira、Kiryu-Seo Sumiko、Konishi Hiroyuki、Ito Mikako、Masuda Akio、Ishiguro Naoki、Imagama Shiro、Kiyama Hiroshi、Ohno Kinji
- Journal Title
  
  Life Sciences
  
  Volume: 263 Pages: 118577-118577
- DOI
  10.1016/j.lfs.2020.118577
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-18K06483, KAKENHI-PROJECT-19K06904, KAKENHI-PROJECT-20K06925, KAKENHI-PROJECT-19K22802, KAKENHI-PROJECT-19K24067, KAKENHI-PROJECT-18H02524, KAKENHI-PROJECT-19H03779, KAKENHI-PROJECT-20H03561, KAKENHI-PROJECT-17K07094
[Journal Article] Inhibition of cyclooxygenase-1 by nonsteroidal anti-inflammatory drugs demethylates MeR2 enhancer and promotes Mbnl1 transcription in myogenic cells.2020
- Author(s)
  Huang K, Masuda A, Chen G, Bushra S, Kamon M, Araki T, Kinoshita M, Ohkawara B, Ito M, Ohno K
- Journal Title
  
  Sci Rep
  
  Volume: 10 Issue: 1 Pages: 2558-2558
- DOI
  10.1038/s41598-020-59517-y
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-18K06058, KAKENHI-PROJECT-19K09565, KAKENHI-PROJECT-19K22802, KAKENHI-PROJECT-17K07094
[Journal Article] Ubiquitination of DNA Damage-Stalled RNAPII Promotes Transcription-Coupled Repair2020
- Author(s)
  Nakazawa Y, Hara Y, Oka Y, Komine O, van den Heuvel D, Guo C, Daigaku Y, Isono M, He Y, Shimada M, Kato K, Jia N, Hashimoto S, Kotani Y, Miyoshi Y, Tanaka M, Sobue A, Mitsutake N, Suganami T, Masuda A, Ohno K, Nakada S, Mashimo T, Yamanaka K, Luijsterburg MS, Ogi T
- Journal Title
  
  Cell
  
  Volume: 19 Issue: 6 Pages: 1228-1244
- DOI
  10.1016/j.cell.2020.02.010
- NAID
  120006871293
- Peer Reviewed / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-18K06058, KAKENHI-PROJECT-18K08508, KAKENHI-PROJECT-18K11639, KAKENHI-PROJECT-18K19585, KAKENHI-PROJECT-19K22802, KAKENHI-PROJECT-18KK0307, KAKENHI-PROJECT-17H00783, KAKENHI-PROJECT-18H03974, KAKENHI-PROJECT-17H01877, KAKENHI-PROJECT-18H03372, KAKENHI-PROJECT-16H06151, KAKENHI-PROJECT-17K12821, KAKENHI-PROJECT-19K21221
[Journal Article] Zonisamide ameliorates progression of cervical spondylotic myelopathy in a rat model2020
- Author(s)
  Kanbara Shunsuke、Ohkawara Bisei、Nakashima Hiroaki、Ohta Kyotaro、Koshimizu Hiroyuki、Inoue Taro、Tomita Hiroyuki、Ito Mikako、Masuda Akio、Ishiguro Naoki、Imagama Shiro、Ohno Kinji
- Journal Title
  
  Scientific Reports
  
  Volume: 10 Issue: 1 Pages: 13138-13138
- DOI
  10.1038/s41598-020-70068-0
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-18K06483, KAKENHI-PROJECT-19K22802, KAKENHI-PROJECT-19H03779, KAKENHI-PROJECT-20H03561
[Journal Article] CTGF/CCN2 facilitates LRP4‐mediated formation of the embryonic neuromuscular junction2020
- Author(s)
  Ohkawara Bisei、Kobayakawa Akinori、Kanbara Shunsuke、Hattori Takako、Kubota Satoshi、Ito Mikako、Masuda Akio、Takigawa Masaharu、Lyons Karen M、Ishiguro Naoki、Ohno Kinji
- Journal Title
  
  EMBO reports
  
  Volume: 21 Issue: 8
- DOI
  10.15252/embr.201948462
- Peer Reviewed / Open Access / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-18K06058, KAKENHI-PROJECT-18K06483, KAKENHI-PROJECT-19K10150, KAKENHI-PROJECT-19K22802, KAKENHI-PROJECT-19H03779, KAKENHI-PROJECT-19H03817, KAKENHI-PROJECT-20H03561, KAKENHI-PROJECT-19K22716
[Journal Article] Mianserin suppresses R-spondin 2-induced activation of Wnt/β-catenin signaling in chondrocytes and prevents cartilage degradation in a rat model of osteoarthritis2019
- Author(s)
  Okura Toshiaki、Ohkawara Bisei、Takegami Yasuhiko、Ito Mikako、Masuda Akio、Seki Taisuke、Ishiguro Naoki、Ohno Kinji
- Journal Title
  
  Scientific Reports
  
  Volume: 9 Issue: 1 Pages: 2808-2808
- DOI
  10.1038/s41598-019-39393-x
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-18K06058, KAKENHI-PROJECT-18K09062, KAKENHI-PROJECT-15K06707, KAKENHI-PROJECT-15K06755
[Journal Article] Differential effects of spinal motor neuron-derived and skeletal muscle-derived Rspo2 on acetylcholine receptor clustering at the neuromuscular junction2018
- Author(s)
  Li Jin、Ito Mikako、Ohkawara Bisei、Masuda Akio、Ohno Kinji
- Journal Title
  
  Scientific Reports
  
  Volume: 8 Issue: 1 Pages: 13577-13577
- DOI
  10.1038/s41598-018-31949-7
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-17K07094, KAKENHI-PROJECT-18K06058, KAKENHI-PROJECT-15K06707, KAKENHI-PROJECT-15K06755
[Journal Article] Lack of Fgf18 causes abnormal clustering of motor nerve terminals at the neuromuscular junction with reduced acetylcholine receptor clusters2018
- Author(s)
  Ito Kenyu、Ohkawara Bisei、Yagi Hideki、Nakashima Hiroaki、Tsushima Mikito、Ota Kyotaro、Konishi Hiroyuki、Masuda Akio、Imagama Shiro、Kiyama Hiroshi、Ishiguro Naoki、Ohno Kinji
- Journal Title
  
  Sceintific Reports
  
  Volume: 8 Issue: 1 Pages: 434-434
- DOI
  10.1038/s41598-017-18753-5
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-15K06707, KAKENHI-PROJECT-16K07055, KAKENHI-PROJECT-17K16688, KAKENHI-PROJECT-15H04840, KAKENHI-PROJECT-18K06058, KAKENHI-PROJECT-16H05446, KAKENHI-PROJECT-15K06755
[Journal Article] MYRF is associated with encephalopathy with reversible myelin vacuolization2018
- Author(s)
  Kurahashi Hirokazu、Azuma Yoshiteru、Masuda Akio、Okuno Tatsuya、Nakahara Eri、Imamura Takuji、Saitoh Makiko、Mizuguchi Masashi、Shimizu Toshiaki、Ohno Kinji、Okumura Akihisa
- Journal Title
  
  Annals of Neurology
  
  Volume: 83 Issue: 1 Pages: 98-106
- DOI
  10.1002/ana.25125
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-17K10086, KAKENHI-PROJECT-15H04840, KAKENHI-PROJECT-18K06058, KAKENHI-PROJECT-18K07890, KAKENHI-PROJECT-15K06755, KAKENHI-PROJECT-15H04872
[Journal Article] Rules and tools to predict the splicing effects of exonic and intronic mutations2018
- Author(s)
  Ohno K, Takeda J, Masuda A.
- Journal Title
  
  Wiley Interdiscip Rev RNA
  
  Volume: 印刷中 Issue: 1
- DOI
  10.1002/wrna.1451
- NAID
  120006473502
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-15K06755, KAKENHI-PROJECT-15H04840
[Journal Article] SRSF1 suppresses selection of intron-distal 5′ splice site of DOK7 intron 4 to generate functional full-length Dok-7 protein2017
- Author(s)
  Ahsan Khalid Bin、Masuda Akio、Rahman Mohammad Alinoor、Takeda Jun-ichi、Nazim Mohammad、Ohkawara Bisei、Ito Mikako、Ohno Kinji
- Journal Title
  
  Sceintific Reports
  
  Volume: 7 Issue: 1 Pages: 10446-10446
- DOI
  10.1038/s41598-017-11036-z
- Peer Reviewed / Open Access / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-15K06707, KAKENHI-PROJECT-15K06755, KAKENHI-PROJECT-15H04840
[Journal Article] Splicing regulation and dysregulation of cholinergic genes expressed at the neuromuscular junction2017
- Author(s)
  Ohno, K. Rahman, M. A. Nazim, M. Nasrin, F. Lin, Y. Takeda, J. I. Masuda, A.
- Journal Title
  
  J Neurochem
  
  Volume: 印刷中 Issue: S2 Pages: 64-72
- DOI
  10.1111/jnc.13954
- Peer Reviewed / Acknowledgement Compliant
- Data Source
  KAKENHI-PROJECT-15K06755, KAKENHI-PROJECT-15H04840
[Journal Article] Competitive regulation of alternative splicing and alternative polyadenylation by hnRNP H and CstF64 determines acetylcholinesterase isoforms2017
- Author(s)
  Nazim, M. Masuda, A. Rahman, M. A. Nasrin, F. Takeda, J. I. Ohe, K. Ohkawara, B. Ito, M. Ohno, K.
- Journal Title
  
  Nucleic Acids Res
  
  Volume: 3 Pages: 1455-1468
- Peer Reviewed / Acknowledgement Compliant / Open Access
- Data Source
  KAKENHI-PROJECT-15K06755
[Journal Article] Six GU-rich (6GUR) FUS-binding motifs detected by normalization of CLIP-seq by Nascent-seq2017
- Author(s)
  Takeda J, Masuda A, Ohno K.
- Journal Title
  
  Gene
  
  Volume: 618 Pages: 57-64
- DOI
  10.1016/j.gene.2017.04.008
- NAID
  120006331826
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-15K06755, KAKENHI-PROJECT-15H04840
[Journal Article] Competitive regulation of alternative splicing and alternative polyadenylation by hnRNP H and CstF64 determines acetylcholinesterase isoforms2017
- Author(s)
  Nazim M, Masuda A, Rahman MA, Nasrin F, Takeda JI, Ohe K, Ohkawara B, Ito M, Ohno K.
- Journal Title
  
  Nucleic Acids Res
  
  Volume: - Pages: 1455-1468
- DOI
  10.1093/nar/gkw823
- Peer Reviewed / Acknowledgement Compliant / Open Access / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-15H04840, KAKENHI-PROJECT-25430049, KAKENHI-PROJECT-15K06707, KAKENHI-PROJECT-15K10050, KAKENHI-PROJECT-15K06755
[Journal Article] R-spondin 2 promotes acetylcholine receptor clustering at the neuromuscular junction via Lgr5.2016
- Author(s)
  Nakashima H., Ohkawara B., Ishigaki S., Fukudome T., Ito K., Tsushima M., Konishi H., Okuno T., Yoshimura T., Ito M., Masuda A., Sobue G., Kiyama H., Ishiguro N., Ohno K.
- Journal Title
  
  Sci Rep
  
  Volume: 22 Issue: 1 Pages: 28512-28512
- DOI
  10.1038/srep28512
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PLANNED-26117002, KAKENHI-PLANNED-26117004, KAKENHI-PROJECT-15H04840, KAKENHI-PROJECT-25430049, KAKENHI-PROJECT-15K06707, KAKENHI-PROJECT-15K06755, KAKENHI-PROJECT-15K09310, KAKENHI-PROJECT-16K07055, KAKENHI-ORGANIZER-26117001
[Journal Article] R-spondin 2 facilitates differentiation of proliferating chondrocytes into hypertrophic chondrocytes by enhancing Wnt/β-catenin signaling in endochondral ossification.2016
- Author(s)
  Takegami Y, Ohkawara B, Ito M, Masuda A, Nakashima H, Ishiguro N, Ohno K.
- Journal Title
  
  Biochem Biophys Res Commun.
  
  Volume: S0006-291X(16) Issue: 1 Pages: 30400-4
- DOI
  10.1016/j.bbrc.2016.03.089
- Peer Reviewed / Acknowledgement Compliant / Open Access
- Data Source
  KAKENHI-PROJECT-15K06707, KAKENHI-PROJECT-25430049, KAKENHI-PROJECT-15K06755
[Journal Article] FUSによるmRNA長の制御2016
- Author(s)
  増田章男、大野欽司
- Journal Title
  
  生化学
  
  Volume: 88 Pages: 244-247
- NAID
  40020843436
- Acknowledgement Compliant
- Data Source
  KAKENHI-PROJECT-15K06755
[Journal Article] FUS-mediated regulation of alternative RNA processing in neurons: insights from global transcriptome analysis2016
- Author(s)
  Akio Masuda. Takeda, J. I. Ohno, K.
- Journal Title
  
  Wiley Interdiscip Rev RNA
  
  Volume: in press Issue: 3 Pages: 330-340
- DOI
  10.1002/wrna.1338
- NAID
  120005893268
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-15K06755, KAKENHI-PROJECT-15H04840
[Journal Article] Molecular hydrogen suppresses activated Wnt-catenin signaling.2016
- Author(s)
  Y. Lin, B. Ohkawara, M. Ito, N. Misawa, K. Miyamoto, Y. Takegami, A. Masuda, S. Toyokuni, K Ohno
- Journal Title
  
  Scientific Report
  
  Volume: 25 Issue: 1 Pages: 31986-31986
- DOI
  10.1038/srep31986
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PLANNED-24108008, KAKENHI-PROJECT-15H04840, KAKENHI-PROJECT-25430049, KAKENHI-PROJECT-15K06707, KAKENHI-PROJECT-15K06755
[Journal Article] Tranilast stimulates endochondral ossification by upregulating SOX9 and RUNX2 promoters.2016
- Author(s)
  Hasegawa S, Kitoh H, Ohkawara B, Mishima K, Matsushita M, Masuda A, Ishiguro N, Ohno K
- Journal Title
  
  Biochemical and Biophysical Research Communications
  
  Volume: 470(2) Issue: 2 Pages: 356-61
- DOI
  10.1016/j.bbrc.2016.01.044
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-24249076, KAKENHI-PROJECT-26670660, KAKENHI-PROJECT-25861306, KAKENHI-PROJECT-15K06755, KAKENHI-PROJECT-15K15548
[Journal Article] Phenylbutazone induces expression of MBNL1 and suppresses formation of MBNL1-CUG RNA foci in a mouse model of myotonic dystrophy2016
- Author(s)
  1.Chen G, Masuda A, Konishi H, Ohkawara B, Ito M, Kinoshita M, Kiyama H, Matsuura T, Ohno K.
- Journal Title
  
  Sci Rep
  
  Volume: 6 Issue: 1 Pages: 25317-25317
- DOI
  10.1038/srep25317
- Peer Reviewed / Acknowledgement Compliant / Open Access / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-15H04840, KAKENHI-PROJECT-26670170, KAKENHI-PROJECT-15K06707, KAKENHI-PROJECT-15K06755, KAKENHI-PROJECT-16K07055
[Journal Article] IntSplice: prediction of the splicing consequences of intronic single-nucleotide variations in the human genome2016
- Author(s)
  Shibata, A. Okuno, T. Rahman, M. A. Azuma, Y. Takeda, J. Masuda, A. Selcen, D. Engel, A. G. Ohno, K.
- Journal Title
  
  J Hum Genet
  
  Volume: 61 Issue: 7 Pages: 633-640
- DOI
  10.1038/jhg.2016.23
- NAID
  120005851030
- Peer Reviewed / Acknowledgement Compliant
- Data Source
  KAKENHI-PROJECT-15K06755
[Journal Article] Global identification of hnRNP A1 binding sites for SSO-based splicing modulation2016
- Author(s)
  Bruun GH, Doktor TK, Borch J-J, Masuda A, Krainer AR, Ohno K, Andresen BS.
- Journal Title
  
  BMC Biol
  
  Volume: 14 Issue: 1 Pages: 54-54
- DOI
  10.1186/s12915-016-0279-9
- Peer Reviewed / Acknowledgement Compliant / Open Access / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-15H04840, KAKENHI-PROJECT-15K06755
[Journal Article] Arginine methylation of ubiquitin-associated protein 2-like is required for the accurate distribution of chromosomes.2016
- Author(s)
  Maeda M, Hasegawa H, Sugiyama M, Hyodo T, Ito S, Chen D, Asano E, Masuda A, Hasegawa Y, Hamaguchi M, Senga T
- Journal Title
  
  FASEB Journal
  
  Volume: 30 Issue: 1 Pages: 312-323
- DOI
  10.1096/fj.14-268987
- Peer Reviewed / Acknowledgement Compliant / Open Access / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-15K14505, KAKENHI-PROJECT-26840007, KAKENHI-PROJECT-15K06755
[Journal Article] Collagen Q and anti-MuSK autoantibody competitively suppress agrin/LRP4/MuSK signaling.2015
- Author(s)
  Otsuka K, Ito M, Ohkawara B, Masuda A, Kawakami Y, Sahashi K, Nishida H, Mabuchi N, Takano A, Engel AG, Ohno K.
- Journal Title
  
  Sci Rep.
  
  Volume: 5 Issue: 1 Pages: 13928-13928
- DOI
  10.1038/srep13928
- Peer Reviewed / Open Access / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-15K06707, KAKENHI-PROJECT-25430049, KAKENHI-PROJECT-15H04840, KAKENHI-PROJECT-24500469
[Journal Article] Meclozine promotes longitudinal skeletal growth in transgenic mice with achondroplasia carrying a gain-of-function mutation in the FGFR3 gene2015
- Author(s)
  Matsushita M, Hasegawa S, Kitoh H, Mori K, Ohkawara B, Yasoda A, Masuda A, Ishiguro N, Ohno K,
- Journal Title
  
  Endocrinology
  
  Volume: 156 Issue: 1 Pages: 584-554
- DOI
  10.1016/j.fob.2014.11.007
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-24500469, KAKENHI-ORGANIZER-26117001, KAKENHI-PLANNED-26117002
[Journal Article] SRSF1 and hnRNP H antagonistically regulate splicing of COLQ exon 16 in a congenital myasthenic syndrome.2015
- Author(s)
  Rahman MA, Azuma Y, Nasrin F, Takeda J, Nazim M, Bin Ahsan K, Akio Masuda, Engel AG, Ohno K.
- Journal Title
  
  Sci Rep.
  
  Volume: 5 Issue: 1 Pages: 13208-13208
- DOI
  10.1038/srep13208
- Peer Reviewed / Open Access / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-15K06755, KAKENHI-PUBLICLY-25118508, KAKENHI-PROJECT-15H04840, KAKENHI-PROJECT-24500469
[Journal Article] Inhibition of SNW1 association with spliceosomal proteins promotes apoptosis in breast cancer cells.2015
- Author(s)
  Sato N, Maeda M, Sugiyama M, Ito S, Hyodo T, Masuda A, Tsunoda N, Kokuryo T, Hamaguchi M, Nagino M, Senga T
- Journal Title
  
  Cancer Medicine
  
  Volume: ４ Issue: 2 Pages: 268-77
- DOI
  10.1002/cam4.366
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-25650063
[Journal Article] Congenital myasthenic syndrome in Japan: ethnically unique mutations in muscle nicotinic acetylcholine receptor subunits2015
- Author(s)
  Azuma Y, Nakata T, Tanaka M, Shen XM, Ito M, Iwata S, Okuno T, Nomura Y, Ando N, Ishigaki K, Ohkawara B, Masuda A, Natsume J, Kojima S, Sokabe M, Ohno K.
- Journal Title
  
  Neuromuscul Disord
  
  Volume: 25(1) Issue: 1 Pages: 60-69
- DOI
  10.1016/j.nmd.2014.09.002
- Peer Reviewed / Acknowledgement Compliant / Open Access
- Data Source
  KAKENHI-PROJECT-24390221, KAKENHI-PROJECT-25430049, KAKENHI-PROJECT-24247028
[Journal Article] Congenital myasthenic syndrome in Japan: ethnically unique mutations in muscle nicotinic acetylcholine receptor subunits2015
- Author(s)
  Azuma Y, Nakata T, Tanaka M, Shen X M, Ito M, Iwata S, Okuno T, Nomura Y, Ando N, Ishigaki K, Ohkawara B, Masuda A, Natsume J, Kojima S, Sokabe M, Ohno K
- Journal Title
  
  Neuromuscul Disord
  
  Volume: 25 Issue: 2 Pages: 60-69
- DOI
  10.1210/en.2014-1914
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-24500469, KAKENHI-ORGANIZER-26108001, KAKENHI-PLANNED-26108006, KAKENHI-PROJECT-26461381, KAKENHI-PROJECT-15K15548
[Journal Article] Position-specific binding of FUS to nascent RNA regulates mRNA length.2015
- Author(s)
  Masuda A, Takeda J, Okuno T, Okamoto T, Ohkawara B, Ito M, Ishigaki S, Sobue G, Ohno K.
- Journal Title
  
  Genes Dev.
  
  Volume: 29(10) Issue: 10 Pages: 1045-57
- DOI
  10.1101/gad.255737.114
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-15K06707, KAKENHI-PROJECT-15K06755, KAKENHI-PROJECT-15K09310, KAKENHI-PROJECT-25430049, KAKENHI-PUBLICLY-25118508, KAKENHI-PLANNED-26117002, KAKENHI-PLANNED-26117004, KAKENHI-PROJECT-15H04840, KAKENHI-PROJECT-24500469
[Journal Article] A missense mutation in domain III in HSPG2 in Schwartz-Jampel syndrome compromises secretion of perlecan into the extracellular space.2015
- Author(s)
  Iwata S, Ito M, Nakata T, Noguchi Y, Okuno T, Ohkawara B, Masuda A, Goto T, Adachi M, Osaka H, Nonaka R, Arikawa-Hirasawa E, Ohno K.
- Journal Title
  
  Neuromuscul Disord.
  
  Volume: 25(8) Issue: 8 Pages: 667-71
- DOI
  10.1016/j.nmd.2015.05.002
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-15K06707, KAKENHI-PROJECT-15K09326, KAKENHI-PROJECT-25430049, KAKENHI-PROJECT-15H04840, KAKENHI-PROJECT-24500469
[Journal Article] Verapamil protects against cartilage degradation in osteoarthritis by inhibiting Wnt/β-catenin signaling.2014
- Author(s)
  Takamatsu, A., Ohkawara, B., Ito, M., Masuda, A., Sakai, T., Ishiguro, N. and Ohno, K.
- Journal Title
  
  PLOS ONE
  
  Volume: 9(3) Issue: 3 Pages: e92699-e92699
- DOI
  10.1371/journal.pone.0092699
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-23700422, KAKENHI-PROJECT-23710253, KAKENHI-PROJECT-24500469, KAKENHI-PROJECT-24659672, KAKENHI-PROJECT-25430049
[Journal Article] LRP4 induces extracellular matrix productions and facilitates chondrocyte differentiation2014
- Author(s)
  Asai N, Ohkawara B, Ito M, Masuda A, Ishiguro N, Ohno K
- Journal Title
  
  Biochem Biophys Res Commun.
  
  Volume: 451 Issue: 2 Pages: 302-307
- DOI
  10.1016/j.bbrc.2014.07.125
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-24500469, KAKENHI-PROJECT-25430049
[Journal Article] LRP4 third β-propeller domain mutations cause novel congenital myasthenia by compromising agrin-mediated MuSK signaling in a position-specific manner2014
- Author(s)
  Ohkawara B, Cabrera-Serrano M, Nakata T, Milone M, Asai N, Ito K, Ito M, Masuda A, Ito Y, Engel AG, Ohno K
- Journal Title
  
  Hum Mol Genet.
  
  Volume: Apr 1;23(7) Issue: 7 Pages: 1856-68
- DOI
  10.1093/hmg/ddt578
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-23710253, KAKENHI-PROJECT-24390221, KAKENHI-PROJECT-24500469, KAKENHI-PUBLICLY-25118508, KAKENHI-PROJECT-25430049, KAKENHI-PROJECT-25670164, KAKENHI-PROJECT-15H04840
[Journal Article] HnRNP C, YB-1 and hnRNP L coordinately enhance skipping of human MUSK exon 10 to generate a Wnt-insensitive MuSK isoform2014
- Author(s)
  Nasrin F, Rahman MA, Masuda A, Ohe K, Takeda J, Ohno K.
- Journal Title
  
  Sci Rep
  
  Volume: 4 Issue: 1 Pages: 6841-6841
- DOI
  10.1038/srep06841
- Peer Reviewed / Acknowledgement Compliant / Open Access
- Data Source
  KAKENHI-PROJECT-24390221, KAKENHI-PROJECT-24500469, KAKENHI-PUBLICLY-25118508
[Journal Article] Clinically applicable antianginal agents suppress osteoblastic transformation of myogenic cells and heterotopic ossifications in mice2013
- Author(s)
  Yamamoto R, Matsushita M, Kitoh H, Masuda A, Ito M, Katagiri T, Kawai T, Ishiguro N, Ohno K
- Journal Title
  
  J Bone Miner Metab
  
  Volume: 31 Pages: 26-33
- DOI
  10.1007/s00774-012-0380-2
- NAID
  10031168834
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-22300244, KAKENHI-PROJECT-23700422, KAKENHI-PROJECT-24390221, KAKENHI-PROJECT-24500469, KAKENHI-PROJECT-24592230, KAKENHI-PROJECT-24592278
[Journal Article] Mutations in the C-Terminal Domain of ColQ in Endplate Acetylcholinesterase Deficiency Compromise ColQ-MuSK Interaction.2013
- Author(s)
  Nakata T, Ito M, Azuma Y, Otsuka K, Noguchi Y, Komaki H, Okumura A, Shiraishi K, Masuda A, Natsume J, Kojima S, Ohno K.
- Journal Title
  
  Human Mutation
  
  Volume: in press Issue: 7 Pages: 997-1004
- DOI
  10.1002/humu.22325
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-23700422, KAKENHI-PROJECT-24390221, KAKENHI-PROJECT-24500469, KAKENHI-PROJECT-25430049, KAKENHI-PROJECT-25670164
[Journal Article] HnRNP L and hnRNP LL antagonistically modulate PTB-mediated splicing suppression of CHRNA1 pre-mRNA.2013
- Author(s)
  Rahman, M. A., Masuda, A., Ohe, K., Ito, M. , Hutchinson, D. O., Mayeda, A., Engel, A. G. and Ohno, K.
- Journal Title
  
  Sci. Rep.
  
  Volume: 3 Issue: 1 Pages: 2931-2931
- DOI
  10.1038/srep02931
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-23700422, KAKENHI-PROJECT-24390221, KAKENHI-PROJECT-24500469, KAKENHI-PROJECT-24591920, KAKENHI-PROJECT-25430049, KAKENHI-PROJECT-25670164
[Journal Article] FUS-regulated region- and cell-type-specific transcriptome is associated with cell selectivity in ALS/FTLD.2013
- Author(s)
  Fujioka Y, Ishigaki S, Masuda A, Iguchi Y, Udagawa T, Watanabe H, Katsuno M, Ohno K, Sobue G.
- Journal Title
  
  Sci Rep.
  
  Volume: 3 Issue: 1 Pages: 2388-2388
- DOI
  10.1038/srep02388
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-24500469, KAKENHI-PROJECT-24659429
[Journal Article] Meclozine facilitates proliferation and differentiation of chondrocytes by attenuating abnormally activated FGFR3 signaling in achondroplasia.2013
- Author(s)
  Matsushita, M., Kitoh, H., Ohkawara, B., Mishima, K., Kaneko, H., Ito, M., Masuda, A., Ishiguro, N. and Ohno, K.
- Journal Title
  
  PLOS ONE
  
  Volume: 8(12) Issue: 12 Pages: 81569-81569
- DOI
  10.1371/journal.pone.0081569
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-23700422, KAKENHI-PROJECT-23710253, KAKENHI-PROJECT-24249076, KAKENHI-PROJECT-24500469, KAKENHI-PROJECT-24592230, KAKENHI-PROJECT-24592259, KAKENHI-PROJECT-24659671, KAKENHI-PROJECT-25430049
[Journal Article] The ALS/FTLD-related RNA-binding proteins TDP-43 and FUS have common downstream RNA targets in cortical neurons2013
- Author(s)
  Honda D, Ishigaki S, Iguchi Y, Fujioka Y, Udagawa T, Masuda A, Ohno K, Katsuno M, Sobue G.
- Journal Title
  
  FEBS Open Bio.
  
  Volume: 20 Issue: 1 Pages: 1-10
- DOI
  10.1016/j.fob.2013.11.001
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-24500469, KAKENHI-PROJECT-24659429, KAKENHI-PROJECT-25860708
[Journal Article] Protein-anchoring strategy for delivering acetylcholinesterase to the neuromuscular junction2012
- Author(s)
  Ito M, Suzuki Y, Okada T, Fukudome T, Yoshimura T, Masuda A, Takeda S, Krejci E, Ohno K
- Journal Title
  
  Mol Ther
  
  Volume: (印刷中) Issue: 7 Pages: 1384-1392
- DOI
  10.1038/mt.2012.34
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-21390266, KAKENHI-PROJECT-22300244, KAKENHI-PROJECT-22390284, KAKENHI-PROJECT-23700422, KAKENHI-PROJECT-24390221, KAKENHI-PROJECT-24500469
[Journal Article] Position-dependent FUS-RNA interactions regulate alternative splicing events and transcriptions.2012
- Author(s)
  Ishigaki S, Masuda A, Fujioka Y, Iguchi Y, Katsuno M, Shibata A, Urano F, Sobue G, Ohno K
- Journal Title
  
  Sci Rep
  
  Volume: 2 Issue: 1 Pages: 529-529
- DOI
  10.1038/srep00529
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-23659452, KAKENHI-PROJECT-24390221, KAKENHI-PROJECT-24500469, KAKENHI-PROJECT-24659429, KAKENHI-PLANNED-22110005
[Journal Article] Four parameters increase the sensitivity and specificity of the exon array analysis and disclose twenty-five novel aberrantly spliced exons in myotonic dystrophy.2012
- Author(s)
  Yamashita Y, Matsuura T, Shinmi J, Amakusa Y, Masuda A, Ito M, Kinoshita M, Furuya H, Abe K, Ibi T, Sahashi K, Ohno K.
- Journal Title
  
  Journal of Human Genetics
  
  Volume: 57 Issue: 6 Pages: 368-374
- DOI
  10.1038/jhg.2012.37
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-23659455, KAKENHI-PROJECT-23700422, KAKENHI-PROJECT-24390083, KAKENHI-PROJECT-24390221, KAKENHI-PROJECT-24500469
[Journal Article] CUGBP1 and MBNL1 preferentially bind to 3’ UTRs and facilitate mRNA decay2012
- Author(s)
  Masuda A, Andersen HS, Doktor TK, Okamoto T, Ito M, Andresen BS, Ohno K
- Journal Title
  
  Sci Rep
  
  Volume: 2 Issue: 1 Pages: 209-209
- DOI
  10.1038/srep00209
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-22300244, KAKENHI-PROJECT-24390221
[Journal Article] CUGBP1 and MBNL1 preferentially bind to 3' UTRs and facilitate mRNA decay2012
- Author(s)
  Masuda A, Andersen HS, Doktor TK, Okamoto T, Ito M, Andresen BS, Ohno K
- Journal Title
  
  Scientific Reports
  
  Volume: 2 Pages: 209-209
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-21390266
[Journal Article] AG-dependent 3'-splice sites are predisposed to aberrant splicing due to amutation at the first nucleotide of an exon2011
- Author(s)
  Fu Y, Masuda A, Ito M, Shinmi J, Ohno K
- Journal Title
  
  Nucleic Acids Research
  
  Volume: 39 Pages: 4396-4404
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-21390266
[Journal Article] AG-dependent 3'-splice sites are predisposed to aberrant splicing due to a mutation at the first nucleotide of an exon.2011
- Author(s)
  Fu Y, Masuda A, Ito M, Shinmi J, Ohno K.
- Journal Title
  
  Nucleic Acids Res. 39(10)
  
  Pages: 4396-4404
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-20200021
[Journal Article] Hyperuricemia cosegregating with osteogenesis imperfecta is associated with a mutation in GPATCH82011
- Author(s)
  Kaneko H, Kitoh H, Matsuura T, Masuda A, Ito M, Mottes M, Rauch F, Ishiguro N, Ohno K
- Journal Title
  
  Hum Genet
  
  Volume: 130 Issue: 5 Pages: 671-683
- DOI
  10.1007/s00439-011-1006-9
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-21390266, KAKENHI-PROJECT-21390419, KAKENHI-PROJECT-21591915, KAKENHI-PROJECT-22659269, KAKENHI-PROJECT-22659270
[Journal Article] Hyperuricemia cosegregating with osteogenesis imperfecta is associated with amutation in2011
- Author(s)
  Kaneko H, Kitoh H, Matsuura T, Masuda A, Ito M, Mottes M, Rauch F, Ishiguro N, Ohno K
- Journal Title
  
  GPATCH8
  
  Volume: 130 Pages: 671-683
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-21390266
[Journal Article] AG-dependent 3'-splice sites are predisposed to aberrant splicing due to a mutation at the first nucleotide of an exon2011
- Author(s)
  Fu Y, Masuda A, Ito M, Shinmi J, Ohno K
- Journal Title
  
  Nucleic Acids Research
  
  Volume: 39 Issue: 10 Pages: 4396-4404
- DOI
  10.1093/nar/gkr026
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-21390266
[Journal Article] Anti-MuSK autoantibodies block binding of collagen Q to MuSK2011
- Author(s)
  Kawakami Y, Ito M, Hirayama M, Sahashi K, Ohkawara B, Masuda A, Nishida H, Mabuchi N, Engel A G, Ohno K
- Journal Title
  
  Neurology
  
  Volume: 77 Pages: 1819-1826
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-21390266
[Journal Article]2010
- Author(s)
  Chiba N, Kakimoto K, Masuda A, Matsuguchi T.
- Journal Title
  
  Biochem Biophys Res Commun. 402
  
  Pages: 1-6
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-20591186
[Journal Article]2009
- Author(s)
  Bian Y, Masuda A, Matsuura T, Ito M, Okushin K, Engel AG, Ohno K.
- Journal Title
  
  Hum Mol Genet 18
  
  Pages: 1229-1237
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-20591186
[Journal Article] Molecular hydrogen suppresses FcepsilonRI-mediated signal transduction and prevents degranulation of mast cells.2009
- Author(s)
  Itoh T, Fujita Y, Ito M, Masuda A, Ohno K, Ichihara M, Kojima T, Nozawa Y, Ito M.
- Journal Title
  
  Biochem Biophys Res Commun. 389(4)
  
  Pages: 651-656
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-20200021
[Journal Article] Tannic acid facilitates expression of the polypyrimidine tract binding protein and alleviates deleterious inclusion of CHRNA1 exon P3Adue to an hnRNP H-disrupting mutation in congenital myasthenic syndrome2009
- Author(s)
  Bian Y, Masuda A, Matsuura T, Ito M, Okushin K, Engel AG, Ohno K
- Journal Title
  
  Hum Mol Genet
  
  Volume: 18 Pages: 1229-1237
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-21390266
[Journal Article]2009
- Author(s)
  Ohno K, Ito M, Masuda A.
- Journal Title
  
  Nihon Shinkei Seishin Yakurigaku Zasshi. 29(4)
  
  Pages: 145-151
- Data Source
  KAKENHI-PROJECT-20591186
[Journal Article] Tannic acid facilitates expression of the polypyrimidine tract binding protein and alleviates deleterious inclusion of CHRN A1 exon P3A due to an hnRNP H-disrupting mutation in congenital myasthenic syndrome2009
- Author(s)
  Bian Y, Masuda A, Matsuura T, Ito M, Okushin K, Engel AG, Ohno K.
- Journal Title
  
  Hum Mol Genet Vol. 18
  
  Pages: 1229-1237
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-21390266
[Journal Article]2009
- Author(s)
  Matsuguchi T, Chiba N, Bandow K, Kakimoto K, Masuda A, Ohnishi T.
- Journal Title
  
  J Bone Miner Res. 24(3)
  
  Pages: 398-410
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-20591186
[Journal Article] Molecular hydrogen is protective against 6-hydroxydopamine-induced nigrostriatal degeneration in a rat model of Parkinson's disease2009
- Author(s)
  Fu Y, Ito M, Fujita Y, Ito M, Ichihara M, Masuda A, Suzuki Y, Maesawa S, Kajita Y, Hirayama M, Ohsawa I, Ohta S, Ohno K.
- Journal Title
  
  Neurosci Lett Vol. 453
  
  Pages: 81-85
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-21390266
[Journal Article] Molecular hydrogen is protective against 6-hydroxydopamine-induced nigrostriatal degeneration in a rat model of Parkinson's disease.2009
- Author(s)
  Fu Y, Ito M, Fujita Y, Ito M, Ichihara M, Masuda A, Suzuki Y, Maesawa S, Kajita Y, Hirayama M, Ohsawa I, Ohta S, Ohno K.
- Journal Title
  
  Neurosci Lett. 453(2)
  
  Pages: 81-85
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-20200021
[Journal Article] JNK activity is essential for Atf4 expression and late-stage osteoblast differentiation.2009
- Author(s)
  Matsuguchi T, Chiba N, Bandow K, Kakimoto K, Masuda A, Ohnishi T.
- Journal Title
  
  J Bone Miner Res. 24(3)
  
  Pages: 398-410
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-20200021
[Journal Article] Molecular hydrogen suppresses FcepsilonRI-mediated signal transduction and prevents degranulation of mast cells2009
- Author(s)
  Itoh T, Fujita Y, Ito M, Masuda A, Ohno K, Ichihara M, Kojima T, Nozawa Y, Ito M.
- Journal Title
  
  Biochem Biophys Res Commun Vol. 389
  
  Pages: 651-656
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-21390266
[Journal Article]2009
- Author(s)
  Fu Y, Ito M, Fujita Y, Ito M, Ichihara M, Masuda A, Suzuki Y, Maesawa S, Kajita Y, Hirayama M, Ohsawa I, Ohta S, Ohno K.
- Journal Title
  
  Neuroscience Letters 453
  
  Pages: 81-85
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-20591186
[Journal Article]2008
- Author(s)
  Masuda A, Shen X-M, Ito M, Matsuura T, Engel AG, Ohno K.
- Journal Title
  
  Hum Mol Genet. 17
  
  Pages: 4022-4035
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-20591186
[Journal Article]2008
- Author(s)
  Ito M, Masuda A, Jinno S, Katagiri T, Krejci E, Ohno K.
- Journal Title
  
  Chem Biol Interact. 175
  
  Pages: 346-348
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-20591186
[Journal Article] Human branch point consensus sequence is yUnAy.2008
- Author(s)
  Gao K, Masuda A, Matsuura T, Ohno K.
- Journal Title
  
  Nucleic Acids Res. 36(7)
  
  Pages: 2257-2267
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-20200021
[Journal Article] hnRNP H enhances skipping of a nonfunctional exon P3A in CHRNA1 and a mutation disrupting its binding causes congenital myasthenic syndrome2008
- Author(s)
  Masuda A, Shen XM, Ito M, Matsuura T, Engel AG, Ohno K
- Journal Title
  
  Hum Mol Genet Vol.17
  
  Pages: 4022-4035
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-19390237
[Journal Article] Human branch point consensus sequence is yunay2008
- Author(s)
  Gao K, Masuda A, Matsuura T, Ohno K
- Journal Title
  
  Nucleic Acids Res 36
  
  Pages: 2257-2267
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-19390237
[Journal Article] hnRNP H enhances skipping of a nonfunctional exon P3A in CHRNA1 and a mutation disrupting its binding causes congenital myasthenic syndrome.2008
- Author(s)
  Masuda A, Shen XM, Ito M, Matsuura T, Engel AG, Ohno K.
- Journal Title
  
  Hum Mol Genet. 17(24)
  
  Pages: 4022-4035
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-20200021
[Journal Article] hnRNP H enhances skipping of a nonfunctional exon P3A in CH RNA1 and a mutation disrupting its binding causes congenital my asthenic syndrome2008
- Author(s)
  Masuda A
- Journal Title
  
  Hum Mol Genet 17
  
  Pages: 4022-4035
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-20200021
[Journal Article] HnRNP H enhances skipping of a nonfunctional exon P3A in CHRNA1 and a mutation disrupting its binding causes congenital myas thenic syndrome2008
- Author(s)
  Akio Masuda
- Journal Title
  
  Hum Mol Genet 17
  
  Pages: 4022-4035
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-20591186
[Journal Article] Human branch point consensus sequence is yUnAy2008
- Author(s)
  Gao K, Masuda A, Matsuura T, Ohno K.
- Journal Title
  
  Nucleic Acids Res Vol.36
  
  Pages: 2257-2267
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-19390237
[Journal Article] Viral vector-mediated expression of human collagen Q in cultured cells.2008
- Author(s)
  Ito M, Masuda A, Jinno S, Katagiri T, Krejci E, Ohno K.
- Journal Title
  
  Chem Biol Interact. 175(1-3)
  
  Pages: 346-348
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-20200021
[Journal Article]2008
- Author(s)
  Gao K, Masuda A, Matsuura T, Ohno K.
- Journal Title
  
  Nucleic Acids Research 36
  
  Pages: 2257-2267
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-20591186
[Journal Article] hnRNP H enhances skipping of a nonfunctional exon P3A in CHRNA1 and a mutation disrupting its binding causes congenital myasthenic syndrome2008
- Author(s)
  Masuda A, Shen XM, Ito M, Matsuura T, Engel AG, Ohno K
- Journal Title
  
  Hum Mol Genet 17
  
  Pages: 4022-4035
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-19390237
[Journal Article] Thermodynamic instability of siRNA duplex is a prerequisite for dependable prediction of siRNA activities2007
- Author(s)
  Ichihara M, Murakumo Y, Masuda A, Matsuura T, Asai N, Jijiwa M, Ishida M, Shinmi J, Yatsuya H, Qiao S, Takahashi M, Ohno K
- Journal Title
  
  Nucleic Acids Res 35
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-19390237
[Journal Article] Essential role of GATA transcriptional factors in the activation of mast cells.2007
- Author(s)
  Akio Masuda
- Journal Title
  
  The Journal of Immunology 178・1
  
  Pages: 360-360
- Data Source
  KAKENHI-PROJECT-17700347
[Journal Article] Essential role of GATA transcriptional factors in the activation of mast cells2007
- Author(s)
  Masuda A, Hashimoto K, Yokoi T, Doi, T, Kodama, T, Kume, H, Ohno, K, Matsuguchi, T
- Journal Title
  
  J Immunol 178
  
  Pages: 360-368
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-19390237
[Journal Article] In vitro and in silico analysis reveals an efficient algorithm to predict the splicing consequences of mutations at the 5' splice sites2007
- Author(s)
  Sahashi K, Masuda A, Matsuura T, Shinmi J, Zhang Z, Takeshima Y, Matsuo M, Sobue G, Ohno K
- Journal Title
  
  Nucleic Acids Res 35
  
  Pages: 5995-6003
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-19390237
[Journal Article] Protein-anchoring strategy for delivering acetyl cholinesterase to the neuromuscular junction
- Author(s)
  Ito M, Suzuki Y, Okada T, FukudomeT, Yoshimura T, Masuda A, Takeda S, Krejci E, Ohno K
- Journal Title
  
  Mol Ther
  
  Volume: (in press)
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-21390266
[Patent] タンパク質－ＲＮＡ相互作用の検出2017
- Inventor(s)
  増田章男、大野欽司
- Industrial Property Rights Holder
  名古屋大学
- Industrial Property Rights Type
  特許
- Filing Date
  2017
- Data Source
  KAKENHI-PROJECT-15K06755
[Presentation] RNA-binding proteins form meshworks in nuclei to regulate splicing2023
- Author(s)
  Akio Masuda and Takaaki Okamoto
- Organizer
  2023 日本生化学学会
- Data Source
  KAKENHI-PROJECT-22K19269
[Presentation] Spatial organization of RNA-binding protein networks to regulate splicing2023
- Author(s)
  Takaaki Okamoto and Akio Masuda
- Organizer
  24th Annual Meeting of the RNA society of Japan
- Data Source
  KAKENHI-PROJECT-23K21309
[Presentation] Spatial organization of RNA-binding protein networks to regulate splicing2023
- Author(s)
  Takaaki Okamoto and Akio Masuda
- Organizer
  24th Annual Meeting of the RNA society of Japan
- Data Source
  KAKENHI-PROJECT-22K19269
[Presentation] RNA-binding proteins form meshworks in nuclei to regulate splicing2023
- Author(s)
  Akio Masuda and Takaaki Okamoto
- Organizer
  2023 日本生化学会大会
- Data Source
  KAKENHI-PROJECT-23K21309
[Presentation] 液―液相分離が規定するRNA代謝2023
- Author(s)
  増田章男
- Organizer
  2023　富山大学大学院生命融合科学教育部セミナー/富山RNA倶楽部
- Invited
- Data Source
  KAKENHI-PROJECT-22K19269
[Presentation] 液―液相分離が規定するRNA代謝2023
- Author(s)
  増田章男
- Organizer
  2023　富山大学大学院生命融合科学教育部セミナー/富山RNA倶楽部
- Invited
- Data Source
  KAKENHI-PROJECT-23K21309
[Presentation] Interactions between muscle glucose homeostasis and neuromuscular signal transduction - Lessons learned from lack of a muscle-specific long isoform of GFPT1 -2022
- Author(s)
  Farshadyeganeh P, Nazim M, Ohkawara B, Masuda A, Ito M, Takeda J, Ohe K, Ohno K.
- Organizer
  European Human Genetics Conference 2022 (Platform), Vienna, Austria
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-20H03561
[Presentation] Identification of the nuclear speckles enriched with MATR3, which functionally regulate alternative splicing through spatial compartmentalization by LLPS2021
- Author(s)
  Takaaki Okamoto, Akio Masuda, Kinji Ohno
- Organizer
  第44回日本分子生物学会年会
- Data Source
  KAKENHI-PROJECT-18K06058
[Presentation] The suppressive role for the splicing regulator, PTBP1, in the production of neuron-specific agrin isoform2021
- Author(s)
  Bushra S, Lin Y, Joudaki A, Masuda A, Ohno K
- Organizer
  American Society of Human Genetics 2021 (Poster), Virtual Meeting
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-20H03561
[Presentation] Prediction of the splicing effects of SNVs affecting the first nucleotide G of an exon2021
- Author(s)
  Joudaki A, Takeda J, Masuda A, Ohno K
- Organizer
  European Human Genetics Conference 2021 (Poster), Virtual Conference
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-20H03561
[Presentation] The splicing mechanism that secures large exons encoding intrinsic disordered regions of transcription factors2020
- Author(s)
  Toshihiko Kawachi Akio Masuda, Jun-ichi Takeda, Mikako Ito, Tomonari Hamaguchi, Kinji Ohno
- Organizer
  Experimental Biology 2020 Meeting
- Data Source
  KAKENHI-PROJECT-18K06058
[Presentation] 長いエクソンは天然変性領域をコードしており、SRSF3により安定的にスプライスされる2020
- Author(s)
  増田章男　河地利彦　大野欽司
- Organizer
  第43回日本分子生物学会年会
- Data Source
  KAKENHI-PROJECT-18K06058
[Presentation] tRIP法による、RNA polymerase IIによる転写中pre-mRNA上での、RNA-protein相互作用部位の同定2019
- Author(s)
  Akio Masuda, Toshihiko Kawachi, Junichi Takeda, Kinji Ohno
- Organizer
  第42回日本分子生物学会年会
- Data Source
  KAKENHI-PROJECT-18K06058
[Presentation] 新規RNA免疫沈降法(tRIP法）による、FUS－U1 snRNP依存性転写終結制御の解明2018
- Author(s)
  Akio Masuda, Toshihiko Kawachi, Junichi Takeda, Kinji Ohno
- Organizer
  第41回　日本分子生物学会年会
- Data Source
  KAKENHI-PROJECT-18K06058
[Presentation] 新規RNA免疫沈降法(tRIP法）による、FUS－U1 snRNP依存性転写終結制御の解明2018
- Author(s)
  Akio Masuda, Toshihiko Kawachi, Junichi Takeda, Kinji Ohno
- Organizer
  第41回日本分子生物学会　年会
- Data Source
  KAKENHI-PROJECT-15K06755
[Presentation] 新規RNA免疫沈降法による生体内protein-protein-RNA interactionの検出2017
- Author(s)
  増田章男、河地利彦、武田淳一、大野欽司
- Organizer
  第19回日本RNA学会年会
- Data Source
  KAKENHI-PROJECT-15K06755
[Presentation] Binding of FUS to promoter upstream transcripts, PROMPTs, globally regulates gene transcription2016
- Author(s)
  Akio Masuda, Jun-ichi Takeda, Takaaki Okamoto, Kinji Ohno
- Organizer
  RNA society
- Place of Presentation
  国立京都国際会館(京都府京都市)
- Year and Date
  2016-06-28
- Data Source
  KAKENHI-PROJECT-15K06755
[Presentation] FUSはプロモーター領域のアンチセンス鎖RNA (PROMPTs) に結合し、転写制御を行う2016
- Author(s)
  Takaaki Okamoto, Akio Masuda, Jun-ichi Takeda, Kinji Ohno
- Organizer
  日本分子生物学会
- Place of Presentation
  パシフィコ横浜（神奈川県横浜市）
- Year and Date
  2016-11-30
- Data Source
  KAKENHI-PROJECT-15K06755
[Presentation] Interaction between NIFK and ncRNA arising from Ccnd1 promoter region regulates myogenic differentiation2016
- Author(s)
  Yoshihiro Yamashita, Akio Masuda, Kinji Ohno
- Organizer
  RNA society
- Place of Presentation
  国立京都国際会館(京都府京都市)
- Year and Date
  2016-06-28
- Data Source
  KAKENHI-PROJECT-15K06755
[Presentation] 神経疾患関連RNA結合蛋白FUSによる転写開始・終結制御2015
- Author(s)
  増田章男、武田淳一、大野欽司
- Organizer
  第17回RNAミーティング
- Place of Presentation
  ホテルライフォート札幌（北海道札幌市）
- Year and Date
  2015-07-13
- Data Source
  KAKENHI-PROJECT-15K06755
[Presentation] Genome-wide analysis reveals relationship between RNA-binding sites of FUS and transcriptional regulation2013
- Author(s)
  Akio Masuda, Tatsuya Okuno, Takaaki Okamoto, Kinji Ohno
- Organizer
  8th Brain Research Conference: RNA Metabolism in Neurological Disease
- Place of Presentation
  San Diego, USA
- Data Source
  KAKENHI-PROJECT-24500469
[Presentation] FUS regulates transcription termination through binding to nascent RNA2013
- Author(s)
  Akio Masuda, Tatsuya Okuno, Takaaki Okamoto, Kinji Ohno
- Organizer
  Society for Neuroscience
- Place of Presentation
  San Diego, USA
- Data Source
  KAKENHI-PROJECT-24500469
[Presentation] Alternative RNA splicing regulating the molecular architecture of NMJ2013
- Author(s)
  Nasrin F, Rahman MA, Ohe K, Masuda A, Ohno K
- Organizer
  5th NAGOYA Global Retreat (Poster)
- Place of Presentation
  あいち健康プラザ（名古屋市）
- Data Source
  KAKENHI-PROJECT-24390221
[Presentation] Mutation in congenital myasthenic syndrome reveals opposite splicing regulatory effects of hnRNPs L and LL2012
- Author(s)
  Rahman MA, Ohe K, Masuda A, Ito M, Hutchinson DO, Engel AG, Ohno K
- Organizer
  35th Annual Meeting of the Japan Neuroscience Society (Poster)
- Place of Presentation
  名古屋国際会議場（名古屋市）
- Data Source
  KAKENHI-PROJECT-24390221
[Presentation] A comprehensive and efficient algorithm to predict splicing consequences of intronic nucleotide substitutions in the human genome2012
- Author(s)
  Shibata A, Masuda A, Ohno K
- Organizer
  62nd Annual Meeting of the American Society of Human Genetics (Poster)
- Place of Presentation
  San Francisco, USA
- Data Source
  KAKENHI-PROJECT-24390221
[Presentation] Global analysis of RNA-binding sites of CUGBP1 and MBNL1 reveal their preferential binding to 3’ UTRs to regulate mRNA stability2012
- Author(s)
  Masuda A, Andersen HS, Doktor TK, Okamoto T, Ito I, Andresen BS, Ohno K
- Organizer
  The 11th Annual Scientific Meeting of the Asian and Oceanian Myology Center (Poster)
- Place of Presentation
  京都市芝蘭会館（京都市）
- Data Source
  KAKENHI-PROJECT-24390221
[Presentation] Global mapping of FUS-binding sites and global profiling of FUS-mediated RNA metabolisms in the mouse brain2012
- Author(s)
  Masuda A, Ishigaki S, Fujioka Y, Iguchi Y, Katsuno M, Shibata A, Urano F, Sobue G, Ohno K
- Organizer
  62nd Annual Meeting of the American Society of Human Genetics (Poster)
- Place of Presentation
  San Francisco, USA
- Data Source
  KAKENHI-PROJECT-24390221
[Presentation] Protein-anchoring therapy for delivering acetylcholinesterase to theneuromuscular junction2011
- Author(s)
  Ito M, Suzuki Y, Okada T, Fukudome T, Yoshimura T, Masuda A, Takeda S, Krejci E, Ohno K
- Organizer
  4th International Congress of Myology
- Place of Presentation
  Lille, France
- Year and Date
  2011-05-09
- Data Source
  KAKENHI-PROJECT-21390266
[Presentation] Anti-MuSK antibodies in myasthenia gravis block binding of collagen Q to MuSK expressed at the neuromuscular junction2011
- Author(s)
  Kawakami Y, Ito M, Hirayama M, Sahashi K, Ohkawara B, Masuda A, Hishida H, Mabuchi N, Engel AG, Ohno K
- Organizer
  41st Annual Meeting, Society for Neuroscience
- Place of Presentation
  Washington DC, USA
- Year and Date
  2011-11-15
- Data Source
  KAKENHI-PROJECT-21390266
[Presentation] Anti-MuSK antibodies in myastheniagravis block binding of collagen Q toMuSK expressed at theneuromuscular junction2011
- Author(s)
  Kawakami Y, Ito M, Hirayama M, Sahashi K, Ohkawara B, Masuda A, Hishida H, Mabuchi N, Engel AG
- Organizer
  41st Annual Meeting, Society for Neuroscience
- Place of Presentation
  Washington DC, USA
- Year and Date
  2011-11-15
- Data Source
  KAKENHI-PROJECT-21390266
[Presentation] Protein-anchoring therapy for delivering acetylcholinesterase to the neuromuscular junction2011
- Author(s)
  Ito M, Suzuki Y, Okada T, Fukudome T, Yoshimura T, Masuda A, Takeda S, Krejci E, Ohno K
- Organizer
  4th International Congress of Myology
- Place of Presentation
  Lille, France(招待講演)
- Year and Date
  2011-05-09
- Data Source
  KAKENHI-PROJECT-21390266
[Presentation] HITS-CLIP法により同定したスプライシング因子CUGBP1およびMBNL1の標的RNA配列の機能解析2010
- Author(s)
  増田章男
- Organizer
  第12回日本RNA学会年会
- Place of Presentation
  一橋記念講堂(東京都)
- Data Source
  KAKENHI-PROJECT-20200021
[Presentation] 分子状水素によるI型アレルギー抑制の分子機構2010
- Author(s)
  伊藤智広、藤田泰典、伊藤美佳子、増田章男、市原正智、小島俊男、野澤義則、大野欽司、伊藤雅史
- Organizer
  第130回日本薬学会
- Place of Presentation
  岡山
- Data Source
  KAKENHI-PROJECT-20200021
[Presentation] Mutations at the C-terminal domain(CTD) of collagen Q(ColQ) causingacetylcholinesterase(AChE) deficiencyprevent anchoring of ColQ to theneuromuscular junction(NMJ)2010
- Author(s)
  Sugiyama A, Ito M, Nakata T, Azuma Y, Masuda A, Okumura A, Komaki H, Ohno K
- Organizer
  Mutations at the C-terminal domain(CTD) of collagen Q(ColQ) causingacetylcholinesterase(AChE) deficiencyprevent anchoring of ColQ to theneuromuscular junction(NMJ)
- Place of Presentation
  San Diego, USA
- Data Source
  KAKENHI-PROJECT-21390266
[Presentation] Henriette Skovgaard Andersen, Thomas Koed Doktor, Brage Storstein Andresen,大野欽司HITS-CLIP法により同定したスプライシング因子CUGBP1およびMBNL1の標的RNA配列の機能解析2010
- Author(s)
  増田章男
- Organizer
  第12回日本RNA学会年会
- Place of Presentation
  一橋記念講堂(東京)
- Year and Date
  2010-07-27
- Data Source
  KAKENHI-PROJECT-20591186
[Presentation] 分子状水素によるI型アレルギー抑制機構の解明2010
- Author(s)
  伊藤智広、藤田泰典、伊藤美佳子、増田章男、市原正智、小島俊男、野澤義則、大野欽司、伊藤雅史
- Organizer
  日本基礎老化学会第33回大会
- Place of Presentation
  名古屋
- Data Source
  KAKENHI-PROJECT-20200021
[Presentation] HITS-CLIP法により同定したスプライシング因子CUGBP1およびMBNL1の標的RNA配列の機能解析2010
- Author(s)
  増田章男
- Organizer
  第12回日本RNA学会年会
- Place of Presentation
  一橋記念講堂
- Year and Date
  2010-07-27
- Data Source
  KAKENHI-PROJECT-20591186
[Presentation] Mutations at the C-terminal domain (CTD) of collagen Q (ColQ) causing acetylcholinesterase (AChE) deficiency prevent anchoring of ColQ to the neuromuscular junction (NMJ)2010
- Author(s)
  Sugiyama A, Ito M, Nakata T, Azuma Y, Masuda A, Okumura A, Komaki H, Ohno K
- Organizer
  40th Annual Meeting, Society for Neuroscience
- Place of Presentation
  San Diego, USA
- Data Source
  KAKENHI-PROJECT-21390266
[Presentation] Henriette Skovgaard Andersen、Thomas Koed Doktor、Brage Storstein Andresen、大野欽司:HITS-CLIP法により同定したスプライシング因子CUGBP1およびMBNL1の標的RNA配列の機能解析2010
- Author(s)
  増田章男
- Organizer
  第12回日本RNA学会年会
- Place of Presentation
  東京
- Data Source
  KAKENHI-PROJECT-20200021
[Presentation] rAAV8-Mediated Protein-Anchoring Therapy for Targeting Collagen Q-Tailed Acetylcholinesterase to the Neuromuscular Junction2010
- Author(s)
  Ito M, Suzuki Y, Okada T, FukudomeT, Yoshimura T, Masuda A, Takeda S, Krejci E, Ohno K
- Organizer
  American Society of Gene & Cell Therapy 13th Annual Meeting, Washington DC
- Place of Presentation
  USA
- Data Source
  KAKENHI-PROJECT-21390266
[Presentation] rAAV8-Mediated Protein-Anchoring Therapy for Targeting Collagen Q-Tailed Acetylcholinesterase to the Neuromuscular Junction2010
- Author(s)
  Ito M, Suzuki Y, Okada T, Fukudome T, Yoshimura T, Masuda A, Takeda S, Krejci E, Ohno K
- Organizer
  American Society of Gene & Cell Therapy 13th Annual Meeting
- Place of Presentation
  Washington DC, USA
- Data Source
  KAKENHI-PROJECT-21390266
[Presentation] A mutation on a nonfunctional exon P3A inCHRNA1 identified in a patient withcongenital myasthenic syndrome losesbinding affinity for a splicing-suppressinghn RNP L and gains binding affinity for asplicing-enhancing RNP LL2009
- Author(s)
  Rahman MA, Masuda A, Ito M, Ohno K
- Organizer
  2nd GCOE International Symposium
- Place of Presentation
  Nagoya, Japan
- Data Source
  KAKENHI-PROJECT-21390266
[Presentation] AG-independence of the 3'splice site determines tolerance to aberrant splicingdue to a mutation at the first nucleotide of an exon2009
- Author(s)
  Fu Y, Masuda A, Ito M, Ohno K
- Organizer
  2nd GCOE International Symposium
- Place of Presentation
  Nagoya, Japan
- Data Source
  KAKENHI-PROJECT-21390266
[Presentation] Adeno-associated virus serotype 8-mediated targeting of asymmetric acetylcholinesterase to the synaptic basal lamina at the neuromuscular junction.2008
- Author(s)
  Ito M, Suzuki Y, Okada T, Fukudome T, Masuda A, Yoshimura T, Takeda S, Krejci E, Ohno K.
- Organizer
  The 38th Annual Meeting, Society for Neuroscience.
- Place of Presentation
  Washington D. C., USA
- Data Source
  KAKENHI-PROJECT-20200021
[Presentation] rAAV8-mediated protein anchoring of asymmetric acetylcholinesterase (AChE) to the synaptic basal lamina at the neuromuscular junction (NMJ)2008
- Author(s)
  Ito M, Suzuki Y, Okada T, Fukudome T, Masuda A, Yoshimura T, Takeda S, Krejci E, Ohno K
- Organizer
  48th Annual Meeting of the American Society for Cell Biology
- Place of Presentation
  San Francisco, USA
- Data Source
  KAKENHI-PROJECT-19390237
[Presentation] Adeno-associated virus serotype 8-mediated targeting of asymmetric acetylcholinesterase to the synaptic basal lamina at the neuromuscular junction2008
- Author(s)
  Ito M, Suzuki Y, Okada T, Fukudome T, Masuda A, Yoshimura T, Takeda S, Krejci E, Ohno K
- Organizer
  38th Annual Meeting, Society for Neuroscience
- Place of Presentation
  Washington DC, USA
- Data Source
  KAKENHI-PROJECT-19390237
[Presentation] Gene Therapy for Collagen Q defects in congenital myasthenic syndromes2007
- Author(s)
  Ito M, Masuda A, Jinno S, Katagiri T, Krejci E, Ohno K
- Organizer
  The IXth International Meeting on Cholinesterases
- Place of Presentation
  Shuzou, China
- Year and Date
  2007-05-10
- Data Source
  KAKENHI-PROJECT-19390237
[Presentation] IntSplice: A tool to predict aberrant splicing of an SNV at intronic positions -50 to -3
- Author(s)
  Ohno K, Shibata A, Okuno T, Rahman MA, Azuma Y, Masuda A
- Organizer
  64th Annual Meeting of the American Society of Human Genetics
- Place of Presentation
  San Diego, California, USA
- Year and Date
  2014-10-18 – 2014-10-22
- Data Source
  KAKENHI-PROJECT-24390221
[Presentation] Alternative splicing of human MUSK exon 10 is physiologically regulated by multiple splicing regulatory cis-elements and cognate trans-factors
- Author(s)
  Rahman MA, Masuda A, Takeda J, Ohno K
- Organizer
  RNA Biology meeting, Cold Spring Harbor Asia Conference
- Place of Presentation
  Suzhou, China
- Year and Date
  2014-11-10 – 2014-11-14
- Data Source
  KAKENHI-PROJECT-24390221
[Presentation] 神経変性疾患関連RNA結合タンパクFUSによる早期転写終結機構の解明
- Author(s)
  Akio Masuda, Junichi Takeda, Tatsuya Okuno, Kinji Ohno
- Organizer
  第37回日本分子生物学会年会
- Place of Presentation
  パシフィコ横浜(神奈川県横浜市)
- Year and Date
  2014-11-25 – 2014-11-27
- Data Source
  KAKENHI-PROJECT-24500469

1. OHNO Kinji (80397455)

# of Collaborated Projects: 7 results

# of Collaborated Products: 63 results
2. ITO Mikako (60444402)

# of Collaborated Projects: 3 results

# of Collaborated Products: 34 results
3. OHKAWARA Bisei (80589606)

# of Collaborated Projects: 3 results

# of Collaborated Products: 15 results
4. MATSUURA Tohru (90402560)

# of Collaborated Projects: 2 results

# of Collaborated Products: 7 results
5. SENGA Takeshi (80419431)

# of Collaborated Projects: 2 results

# of Collaborated Products: 2 results
6. 石垣診祐 (40378170)

# of Collaborated Projects: 2 results

# of Collaborated Products: 0 results
7. ICHIHARA Masatoshi (00314013)

# of Collaborated Projects: 1 results

# of Collaborated Products: 4 results
8. TAKEUCHI Tamaki (90392018)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
9. MURAKUMO Yoshiki (40324438)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
10. YONEDA Makoto (70270551)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
11. ITO Masafumi (80393114)

# of Collaborated Projects: 1 results

# of Collaborated Products: 10 results
12. Okumura Akihisa (60303624)

# of Collaborated Projects: 1 results

# of Collaborated Products: 2 results
13. 倉橋宏和 (30621817)

# of Collaborated Projects: 1 results

# of Collaborated Products: 1 results
14. 早川昌弘 (40343206)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
15. 藤岡祐介 (70896381)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
16. ITO kengo

# of Collaborated Projects: 0 results

# of Collaborated Products: 1 results
17. 祖父江元

# of Collaborated Projects: 0 results

# of Collaborated Products: 2 results
18. 伊藤智広

# of Collaborated Projects: 0 results

# of Collaborated Products: 1 results
19. 豊國伸哉

# of Collaborated Projects: 0 results

# of Collaborated Products: 1 results
20. 鬼頭浩史

# of Collaborated Projects: 0 results

# of Collaborated Products: 1 results
21. 三島健一

# of Collaborated Projects: 0 results

# of Collaborated Products: 1 results
22. 石黒直樹

# of Collaborated Projects: 0 results

# of Collaborated Products: 1 results

Masuda Akio 増田 章男

MASUDA Akio 増田 章男

増田 章男 マスダ アキオ

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転写から翻訳に向けてmRNAが走る核内基本構造の同定と機能解明Principal Investigator

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辺縁エクソン群に宿る生物進化・機能獲得の鍵Principal Investigator

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in situ cDNA増幅による超高感度 RNA-蛋白 相互作用 解析法の開発Principal Investigator

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天然変性領域 (IDR) 形成を支えるスプライシング機構から俯瞰する相分離現象Principal Investigator

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Identification of the role of transcription termination and polyadenylation in ALS using multiple high-throughput sequencing analysisPrincipal Investigator

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Identification of the role of transcription termination and polyadenylation in the pathogenesis of ALS using multiple high-throughput sequencing analysesPrincipal Investigator

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Identification of specific splicing regulation at neuromuscular junctionsPrincipal Investigator

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Masuda Akio 増田章男

MASUDA Akio 増田章男

増田章男マスダアキオ

in situ cDNA増幅による超高感度 RNA-蛋白相互作用解析法の開発Principal Investigator