Osawa Masatake 大沢匡毅

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OSAWA Masatake 大沢匡毅

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Researcher Number	10344029
Other IDs
Affiliation (Current)	2026: 岐阜大学, 大学院医学系研究科, 教授
Affiliation (based on the past Project Information) *help	2017 – 2025: 岐阜大学, 大学院医学系研究科, 教授 2012 – 2015: 岐阜大学, 医学(系)研究科(研究院), 教授 2011: 岐阜大学, 医学系研究科, 教授 2007: 理研, 研究員 2003 – 2006: RIKEN (The Institute of Physical and Chemical Research), Laboratory for Stem Cell Biology, Research Scientist, 幹細胞研究グループ, 研究員 2002: 理化学研究所, 幹細胞研究グループ, 研究員
Review Section/Research Field	Principal Investigator Dermatology / Basic Section 53050:Dermatology-related / Biological Sciences / Basic Section 53030:Respiratory medicine-related / 幹細胞生物学 / Developmental biology / General medical chemistry Except Principal Investigator Basic Section 53050:Dermatology-related / Basic Section 42020:Veterinary medical science-related / Neurology / Biological Sciences / Veterinary medical science
Keywords	Principal Investigator 色素細胞 / 幹細胞 / トランスジェニックマウス / モデルマウス / 自己免疫 / 尋常性白斑 / 自己免疫疾患 / メラノサイト / 尋常性白斑症 / Melanocytes … More / Stem Cells / 疾患モデルマウス / ゲノム編集 / ES細胞 / 遺伝子機能解析 / ノックダウン / 遺伝子改変マウス / 分化 / アポトーシス / 単細胞遺伝子解析 / 肺発生 / Pmel / LAM細胞 / リンパ脈管筋腫症 / 尋常生白飯 / Npy / 疾患モデル動物 / ニューロペプチドY / 遺伝子操作マウス / 実験動物 / 疾患モデル / Cell-fate deternination / Differentiation / Stem cell niche / 細胞培養 / Single cell PCR / 転写制御 / 遺伝子発現解析 / Stem Cell Niche / Gene Expression Analysis / 細胞運命決定 / 増殖分化制御 / 幹細胞ニッチ / 遺伝子解析 / CRISPR/Cas9 / アトピー性皮膚炎 / 多能性 / ノックアウトマウス / NC/Ngaマウス / 遺伝子ノックダウン / モデル動物 / Notch signaling / Bcl2 / ノツクアウトマウス / Notchシグナリング / 自己複製 / 遺伝子クローニング / Hes1 / Notch / マイクロアレー解析 … More Except Principal Investigator 狂犬病ウイルス / ユビキチン-プロテアソーム分解系 / タンパク質分解誘導薬 / 標的分子探索 / FACS解析 / ALFAタグ / 標的タンパク質分解誘導 / ナノボディ / プロテインノックダウン / 単鎖可変領域フラグメント / ユビキチン化 / E3ユビキチンリガーゼ / ユビキチン / Nras / 抗がん剤 / 標的タンパク質分解 / PROTAC / メラノーマ / 潜伏期 / 末梢感染 / 標的細胞 / PFBC / IBGC / ファール病 / 血管平滑筋細胞 / 周皮細胞 / リン / 血管石灰化 / リン酸 (Pi) / 無機リン酸 (Pi) / 特発性基底核石灰化症 / 原発性家族性脳石灰化症（PFBC） / 特発性基底核石灰化症（IBGC） / 抗酸化剤 / リン酸トランスポーター / 無機リン酸（Pi） / 脳内石灰化 / DNA microarray / mesenchymal stem cell / bulge region / melanocyte / mesoderm / stem cell / endothelial cell / ES cell / VEGFR / がん周囲組織 / 間質細胞 / 平滑筋 / 血液 / 血管内皮 / リンパ節 / VEGF / Ang 1 / ガンの血管新生 / パイエル板 / DNAアレー / 血液分化 / 血管分化 / 抹消リンパ組織 / 血液細胞 / ガン周囲組織 / 血管新生 / 血管リモデリング分子機構 / 色素細胞幹細胞維持機構 / 分化誘導 / マイクロアレー / 間質幹細胞 / バルジ領域 / 色素細胞 / 中胚葉 / 幹細胞 / 血管内皮細 / ES細胞 / 病態発症機序 / トランスジェニックマウス / 病態発生機序 Less

Role of Pmell-positive mesothelial cells in the pathogenesis of lymphangioleiomyomatosis.Principal Investigator
- Principal Investigator
  
  大沢匡毅
- Project Period (FY)
  2025 – 2027
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Review Section
  
  Basic Section 53030:Respiratory medicine-related
- Research Institution
  Gifu University
The physiological role of neuropeptide Y in disease progression of vitiligoPrincipal Investigator
- Principal Investigator
  
  Osawa Masatake
- Project Period (FY)
  2022 – 2024
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Review Section
  
  Basic Section 53050:Dermatology-related
- Research Institution
  Gifu University
Optimizing targeted protein degradation for the therapeutic applications against melanoma
- Principal Investigator
  
  Yazawa Shigenobu
- Project Period (FY)
  2021 – 2023
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Review Section
  
  Basic Section 53050:Dermatology-related
- Research Institution
  Gifu University
Analysis of peripheral infection kinetics of rabies virus by a high-sensitive infection detection system
- Principal Investigator
  
  Ito Naoto
- Project Period (FY)
  2019 – 2021
- Research Category
  
  Grant-in-Aid for Scientific Research (B)
- Review Section
  
  Basic Section 42020:Veterinary medical science-related
- Research Institution
  Gifu University
Establishment of a novel mouse model of vitiligoPrincipal Investigator
- Principal Investigator
  
  Osawa Masatake
- Project Period (FY)
  2019 – 2021
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Review Section
  
  Basic Section 53050:Dermatology-related
- Research Institution
  Gifu University
Research on the molecular mechanism of intracranial calcification and novel therapies
- Principal Investigator
  
  Hozumi Isao
- Project Period (FY)
  2017 – 2020
- Research Category
  
  Grant-in-Aid for Scientific Research (B)
- Research Field
  
  Neurology
- Research Institution
  Gifu Pharmaceutical University
Generation of genetically modified NC/Nga mice using the CRISPR/Cas9-mediated gene editing systemPrincipal Investigator
- Principal Investigator
  
  Osawa Masatake
- Project Period (FY)
  2014 – 2015
- Research Category
  
  Grant-in-Aid for Challenging Exploratory Research
- Research Field
  
  Dermatology
- Research Institution
  Gifu University
Identification of the important viral factor related to the development of rabies by the gene manipulation in mice
- Principal Investigator
  
  Sugiyama Makoto
- Project Period (FY)
  2013 – 2015
- Research Category
  
  Grant-in-Aid for Challenging Exploratory Research
- Research Field
  
  Veterinary medical science
- Research Institution
  Gifu University
A rapid melanocyte-specific transgenesis system for phenotype-based gene function discoveryPrincipal Investigator
- Principal Investigator
  
  OSAWA Masatake
- Project Period (FY)
  2012 – 2013
- Research Category
  
  Grant-in-Aid for Challenging Exploratory Research
- Research Field
  
  Dermatology
- Research Institution
  Gifu University
迅速かつ簡便な組織特異的遺伝子ノックダウンマウス作成法の開発Principal Investigator
- Principal Investigator
  
  大沢匡毅
- Project Period (FY)
  2011 – 2012
- Research Category
  
  Grant-in-Aid for Research Activity Start-up
- Research Field
  
  General medical chemistry
- Research Institution
  Gifu University
メラノーマモデルマウスの作製Principal Investigator
- Principal Investigator
  
  大沢匡毅
- Project Period (FY)
  2007
- Research Category
  
  Grant-in-Aid for Exploratory Research
- Research Field
  
  Dermatology
- Research Institution
  The Institute of Physical and Chemical Research
色素幹細胞をモデルとした幹細胞維持機構の解明Principal Investigator
- Principal Investigator
  
  大沢匡毅
- Project Period (FY)
  2005 – 2006
- Research Category
  
  Grant-in-Aid for Scientific Research on Priority Areas
- Review Section
  
  Biological Sciences
- Research Institution
  The Institute of Physical and Chemical Research
Molecular Characterization of Melanocyte Stem Cells in the NichePrincipal Investigator
- Principal Investigator
  
  OSAWA Masatake
- Project Period (FY)
  2004 – 2005
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Research Field
  
  幹細胞生物学
- Research Institution
  RIKEN
色素幹細胞をモデルとした幹細胞維持機構の解明Principal Investigator
- Principal Investigator
  
  大沢匡毅
- Project Period (FY)
  2003 – 2004
- Research Category
  
  Grant-in-Aid for Scientific Research on Priority Areas
- Review Section
  
  Biological Sciences
- Research Institution
  The Institute of Physical and Chemical Research
Molecular Profiling of Melanocyte Stem CellsPrincipal Investigator
- Principal Investigator
  
  OSAWA Masatake
- Project Period (FY)
  2002 – 2003
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Research Field
  
  Developmental biology
- Research Institution
  RIKEN (The Institute of Physical and Chemical Research)
Production of cells that constitute microenvironment of cancer.
- Principal Investigator
  
  NISHIKAWA Shun-Ichi
- Project Period (FY)
  2000 – 2004
- Research Category
  
  Grant-in-Aid for Scientific Research on Priority Areas
- Review Section
  
  Biological Sciences
- Research Institution
  The Institute of Physical and Chemical Research
  Kyoto University

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All Journal Article Presentation Book

[Book] 毛包形成のメカニズムの解明と毛包再生への応用2013
- Author(s)
  大沢匡毅
- Publisher
  シーエムシー出版
- Data Source
  KAKENHI-PROJECT-24659524
[Book] The promises and challenges of regenerative medicine.2005
- Author(s)
  Nishikawa SI, Osawa M
- Total Pages
  129
- Publisher
  Springer-Verkag, ISSN 0947-6075
- Description
  「研究成果報告書概要(和文)」より
- Data Source
  KAKENHI-PROJECT-16606006
[Journal Article] Weight Gain With Advancing Age Is Controlled by the Muscarinic Acetylcholine Receptor M4 in Male Mice2025
- Author(s)
  Takahashi Toshio、Takase Yuta、Shiraishi Akira、Matsubara Shin、Watanabe Takehiro、Kirimoto Shinji、Yamagaki Tohru、Osawa Masatake
- Journal Title
  
  Endocrinology
  
  Volume: 166 Issue: 6 Pages: 1-16
- DOI
  10.1210/endocr/bqaf064
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-22K06238, KAKENHI-PROJECT-22K08377, KAKENHI-PROJECT-23K05862
[Journal Article] Epithelial-Mesenchymal Transition Functions as a Driver for the Direct Conversion of Somatic Cells2025
- Author(s)
  Motohashi Tsutomu、Aoki Hitomi、Kunisada Takahiro、Osawa Masatake
- Journal Title
  
  Stem Cells and Development
  
  Volume: 34 Issue: 5-6 Pages: 117-126
- DOI
  10.1089/scd.2024.0181
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-22K08377, KAKENHI-PROJECT-22K06808
[Journal Article] Assessing Interferon Regulatory Factor 4 Complex Formation: Differential Behavior of Homocomplexes Versus Heterocomplexes Induced by Mutations2024
- Author(s)
  Li Yupeng、Hirano Setoka、Sato Katsuya、Osawa Masatake、Nagaoka Hitoshi
- Journal Title
  
  Biochemistry
  
  Volume: 63 Issue: 6 Pages: 767-776
- DOI
  10.1021/acs.biochem.3c00512
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-22K06898, KAKENHI-PROJECT-23K06411, KAKENHI-PROJECT-22K08377
[Journal Article] Generation of <i>Pmel</i> ‐dependent conditional and inducible Cre‐driver mouse line for melanocytic‐targeted gene manipulation2022
- Author(s)
  Nasrin Morsheda、Ahmed Osama、Han Xujun、Nojebuzzaman Md、Abo‐Ahmed Ahmed I.、Yazawa Shigenobu、Osawa Masatake
- Journal Title
  
  Pigment Cell & Melanoma Research
  
  Volume: 36 Issue: 1 Pages: 53-70
- DOI
  10.1111/pcmr.13074
- Peer Reviewed / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-21K08297, KAKENHI-PROJECT-22K08377
[Journal Article] Muscarinic receptor M3 contributes to intestinal stem cell maintenance via EphB/ephrin-B signaling2021
- Author(s)
  Takahashi Toshio、Shiraishi Akira、Murata Jun、Matsubara Shin、Nakaoka Satsuki、Kirimoto Shinji、Osawa Masatake
- Journal Title
  
  Life Science Alliance
  
  Volume: 4 Issue: 9 Pages: 1-17
- DOI
  10.26508/lsa.202000962
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-19K08770, KAKENHI-PROJECT-20K06751
[Journal Article] Deficiency of 3‐hydroxybutyrate dehydrogenase (BDH1) in mice causes low ketone body levels and fatty liver during fasting2020
- Author(s)
  Otsuka Hiroki、Kimura Takeshi、Ago Yasuhiko、Nakama Mina、Aoyama Yuka、Abdelkreem Elsayed、Matsumoto Hideki、Ohnishi Hidenori、Sasai Hideo、Osawa Masatake、Yamaguchi Seiji、Mitchell Grant A.、Fukao Toshiyuki
- Journal Title
  
  Journal of Inherited Metabolic Disease
  
  Volume: 43 Issue: 5 Pages: 960-968
- DOI
  10.1002/jimd.12243
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-19K08770, KAKENHI-PROJECT-19K17959
[Journal Article] Upregulated nicotinic ACh receptor signaling contributes to intestinal stem cell function through activation of Hippo and Notch signaling pathways2020
- Author(s)
  Takahashi Toshio、Shiraishi Akira、Osawa Masatake
- Journal Title
  
  International Immunopharmacology
  
  Volume: 88 Pages: 106984-106984
- DOI
  10.1016/j.intimp.2020.106984
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-19K08770, KAKENHI-PROJECT-20K06751
[Journal Article] A DISC1 point mutation promotes oligomerization and impairs information processing in a mouse model of schizophrenia2019
- Author(s)
  Kakuda Kyosuke、Niwa Ayumi、Honda Ryo、Yamaguchi Kei-ichi、Tomita Hiroyuki、Nojebuzzaman Md、Hara Akira、Goto Yuji、Osawa Masatake、Kuwata Kazuo
- Journal Title
  
  The Journal of Biochemistry
  
  Volume: 165 Issue: 4 Pages: 369-378
- DOI
  10.1093/jb/mvy116
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-19K08770
[Journal Article] BNIP3 plays crucial roles in the differentiation and maintenance of epidermal keratinocytes2013
- Author(s)
  Moriyama M, Moriyama H, Uda J, Matsuyama A, Osawa M, Hayakawa T.
- Journal Title
  
  J. Invest. Dermatol. jid
  
  Volume: (Epub ahead of print)
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-24659524
[Journal Article] Indispensable role of Bcl2 in the development of melanocyte stem cell.2006
- Author(s)
  Mak SS, Osawa M, et al.
- Journal Title
  
  Dev Biol 291
  
  Pages: 144-153
- Description
  「研究成果報告書概要(欧文)」より
- Data Source
  KAKENHI-PROJECT-16606006
[Journal Article] Indispensable role of Bcl2 in the development of melanocyte stem cell.2006
- Author(s)
  Siu-Shan Mak, Osawa M, et al.
- Journal Title
  
  Developmental Biology (In press)
- Data Source
  KAKENHI-PROJECT-16606006
[Journal Article] Notch signaling via Hes1 transcription factor maintains survival of melanoblasts and melanocyte stem cells2006
- Author(s)
  Moriyama M, Osawa M, et al.
- Journal Title
  
  Journal of Cell Biology (In press)
- Data Source
  KAKENHI-PROJECT-17045037
[Journal Article] Notch signaling via Hes1 transcription factor maintains survival of melanoblasts and melanocyte stem cells.2006
- Author(s)
  Moriyama M, Masatake Osawa, et al.
- Journal Title
  
  J. Cell Biol 173
  
  Pages: 333-339
- Data Source
  KAKENHI-PROJECT-17045037
[Journal Article] Notch signaling via Hesl transcription factor maintains survival of melanoblasts and melanocyte stem cells2006
- Author(s)
  Moriyama M, Osawa M, et al.
- Journal Title
  
  Journal of Cell Biology 137
  
  Pages: 333-339
- Description
  「研究成果報告書概要(和文)」より
- Data Source
  KAKENHI-PROJECT-16606006
[Journal Article] Notch signaling via Hes1 transcription factor maintains survival of melanoblasts and melanocyte stem cells2006
- Author(s)
  Moriyama M, Osawa M, et al.
- Journal Title
  
  Journal of Cell Biology (In press)
- Data Source
  KAKENHI-PROJECT-16606006
[Journal Article] Notch signaling via Hes1 transcription factor maintains survival of melanoblasts and melanocyte stem cells.2006
- Author(s)
  Moriyama M, Osawa M
- Journal Title
  
  J Cell Biol 137
  
  Pages: 333-339
- Description
  「研究成果報告書概要(欧文)」より
- Data Source
  KAKENHI-PROJECT-16606006
[Journal Article] Indispensable role of Bcl2 in the development of melanocyte stem cell.2006
- Author(s)
  Siu-Shan Mak, Osawa M, et al.
- Journal Title
  
  Developmental Biology (In press)
- Data Source
  KAKENHI-PROJECT-17045037
[Journal Article] Indispensable role of Bc12 in the development of melanocyte stem cell.2006
- Author(s)
  Siu-Shan Mak, Osawa M, et al.
- Journal Title
  
  Developmental Biology 291
  
  Pages: 144-153
- Description
  「研究成果報告書概要(和文)」より
- Data Source
  KAKENHI-PROJECT-16606006
[Journal Article] Indispensable role of Bcl2 in the development of melanocyte stem cell.2006
- Author(s)
  Mak SS, Masatake Osawa et al.
- Journal Title
  
  Dev Biol 291
  
  Pages: 144-153
- Data Source
  KAKENHI-PROJECT-17045037
[Journal Article] Molecular characterization of melanocyte stem cells at the niche.2005
- Author(s)
  Osawa M, Egawa G, et al.
- Journal Title
  
  Development 132・24
  
  Pages: 5589-5599
- Data Source
  KAKENHI-PROJECT-16606006
[Journal Article] Molecular characterization of melanocyte stem cells in their niche.2005
- Author(s)
  Osawa, M., Egawa, G et al.
- Journal Title
  
  Development 132
  
  Pages: 5589-5599
- Description
  「研究成果報告書概要(欧文)」より
- Data Source
  KAKENHI-PROJECT-16606006
[Journal Article] The promises and challenges of regenerative medicine.2005
- Author(s)
  Nishikawa SI, Osawa M.
- Journal Title
  
  Springer. (Morser J, Nishikawa SI (Edit.))
  
  Pages: 1-13
- Description
  「研究成果報告書概要(欧文)」より
- Data Source
  KAKENHI-PROJECT-16606006
[Journal Article] Molecular characterization of melanocyte stem cells at the niche.2005
- Author(s)
  Osawa M, Egawa G, et al.
- Journal Title
  
  Development 132・24
  
  Pages: 5589-5599
- Data Source
  KAKENHI-PROJECT-17045037
[Journal Article] Molecular characterization of melanocyte stem cells at the niche.2005
- Author(s)
  Osawa M, Egawa G, et al.
- Journal Title
  
  Development 132
  
  Pages: 5589-5599
- Description
  「研究成果報告書概要(和文)」より
- Data Source
  KAKENHI-PROJECT-16606006
[Journal Article] Hepatocyte growth factor controls proliferation of cultured epidermal melanoblasts and melanocytes from new born.2004
- Author(s)
  Hirobe.T., Osawa.M., Nishilawa.SI
- Journal Title
  
  Pigment Cell Res. 17
  
  Pages: 51-61
- Data Source
  KAKENHI-PROJECT-16606006
[Journal Article] GM-CSF factor is a kelatinocyte-derived factor involved in regulating the proliferation and differentiation of neonatal mouse epidermal melanocytes.2004
- Author(s)
  Hirobe, T., Furuyama, R., Ifuku, O., Osawa, M., Nishikawa, SI.
- Journal Title
  
  Exp. Cell Res 297
  
  Pages: 593-606
- Data Source
  KAKENHI-PROJECT-15039236
[Journal Article] Hepatocyte Growth Factor Controls the Proliferation of Cultured Epidermal Melanoblasts and Melanocytes from Newborn Mice.2004
- Author(s)
  Hirobe, T., M.Osawa, Nishikawa SI
- Journal Title
  
  Pigment Cell Res 17
  
  Pages: 51-61
- Data Source
  KAKENHI-PROJECT-12219209
[Journal Article] Granulocyte-macrophage colony-stimulating factor is a kelatinocyte-derived factor involved in regulating the proliferation and differentiation of neonatal mouse epidermal melanocytes in culture.2004
- Author(s)
  Hirobe, T, Osawa, M et al.
- Journal Title
  
  Exp.Cell Res. 297
  
  Pages: 593-606
- Description
  「研究成果報告書概要(欧文)」より
- Data Source
  KAKENHI-PROJECT-16606006
[Journal Article] Hepatocyte growth factor controls proliferation of cultured epidermal melanoblasts and melanocytes from newborn mice.2004
- Author(s)
  Hirobe T, Osawa M et al.
- Journal Title
  
  Pigment Cell Research 17
  
  Pages: 51-61
- Description
  「研究成果報告書概要(和文)」より
- Data Source
  KAKENHI-PROJECT-16606006
[Journal Article] Hepatocyte growth factor controls proliferation of cultured epidermal melanoblasts and melanocytes from newborn mice2004
- Author(s)
  Hirobe.T., Osawa.M et al.
- Journal Title
  
  Pigment Cell Res. 17
  
  Pages: 51-61
- Description
  「研究成果報告書概要(欧文)」より
- Data Source
  KAKENHI-PROJECT-16606006
[Journal Article] Granulocyte-macrophage colony stimulating factor is a keratinocyte-derived factor involved in regulating the proliferation and differentiation of neonatal mouse epidermal melanocytes in culture.2004
- Author(s)
  Hirobe T, Osawa M et al.
- Journal Title
  
  Experimental Cell Research 297
  
  Pages: 593-606
- Description
  「研究成果報告書概要(和文)」より
- Data Source
  KAKENHI-PROJECT-16606006
[Journal Article] Hepatocyte growth factor controls proliferation of cultured epidermal melanoblasts and melanocytes from new born.2004
- Author(s)
  Hirobe, T., Osawa, M., Nishilawa, SI
- Journal Title
  
  Pigment Cell Res. 17
  
  Pages: 51-61
- Data Source
  KAKENHI-PROJECT-15039236
[Journal Article] GM-CSF factor is a kelatinocyte-derived factor involved in regulating the proliferation and differentiation of neonatal mouse epidermal melanocytes.2004
- Author(s)
  Hirobe.T., Furuyama.R., Ifuku O., Osawa.M., Nishikawa.SI.
- Journal Title
  
  Exp.Cell Res 297
  
  Pages: 593-606
- Data Source
  KAKENHI-PROJECT-16606006
[Journal Article] Steel factor controls the proliferation and differentiation of neonatal mouse epidermal malanocytes in culture.2003
- Author(s)
  Hirobe, T., Osawa, _M., Nishilawa, SI.
- Journal Title
  
  Pigment Cell Res. 16
  
  Pages: 644-655
- Data Source
  KAKENHI-PROJECT-15039236
[Journal Article] Dominant role of the niche in melanocyte stem-cell fate determination.2002
- Author(s)
  Nishimura EK, Jordan SA, Oshima H, Ybshida H, Osawa M, Moriyama M, Jackson IJ, Barrandon Y, Miyachi Y, Nishikawa S
- Journal Title
  
  Nature 416
  
  Pages: 854-860
- Description
  「研究成果報告書概要(和文)」より
- Data Source
  KAKENHI-PROJECT-12219209
[Journal Article] Dominant role of the niche in melanocyte stem-cell fate determination.2002
- Author(s)
  Nishimura EK, Jordan SA, Oshima H, Yoshida H, Osawa M, Moriyama M, Jackson IJ, Barrandon Y, Miyachi Y, Nishikawa S.
- Journal Title
  
  Nature. 416
  
  Pages: 854-860
- Description
  「研究成果報告書概要(欧文)」より
- Data Source
  KAKENHI-PROJECT-12219209
[Presentation] A novel tool for melanocyte lineage-specific inducible gene manipulation2020
- Author(s)
  Osawa Masatake
- Organizer
  The 24th International Pigment Cell Conference
- Invited / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-19K08770
[Presentation] A novel tool for melanocyte lineage-specific inducible gene manipulation2020
- Author(s)
  Masatake Osawa, Morisheda, Nasrin, Ossama Salem, Xujuun Han
- Organizer
  24th The International Pigment Cell Conference
- Invited / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-19K08770
[Presentation] A rapid melanocyte-specific gene disruption to identify genes involved in the regulation of melanocyte stem cells in the hair follicle.2014
- Author(s)
  大沢　匡毅
- Organizer
  8th World Congress for Hair Research
- Place of Presentation
  韓国　デジュ島
- Invited
- Data Source
  KAKENHI-PROJECT-24659524
[Presentation] A RAPID MELANOCYTE- SPECIFIC GENE DISRUPTION TO IDENTIFY GENES INVOLVED IN THE REGULATION OF MELANOCYTE STEM CELLS IN THE HAIR FOLLICLE J演者2014
- Author(s)
  大沢匡毅
- Organizer
  World Congress for Hair Research 2014
- Place of Presentation
  韓国チェジュ島
- Invited
- Data Source
  KAKENHI-PROJECT-24659524
[Presentation] メラノサイト機能遺伝子を同定するための簡便で迅速な遺伝子改変マウス作成法2012
- Author(s)
  大沢匡毅
- Organizer
  第24回日本色素細胞学会学術大会
- Place of Presentation
  長浜バイオ大学
- Invited
- Data Source
  KAKENHI-PROJECT-24659524
[Presentation] 簡便化ノックダウントランスジェニックマウスによる色素幹細胞制御遺伝子のスクリーニングJ演者2012
- Author(s)
  大沢匡毅
- Organizer
  第一回幹細胞を制御する微少環境の解明を目指した異分野交流研究会
- Place of Presentation
  つくば市
- Invited
- Data Source
  KAKENHI-PROJECT-24659524
[Presentation] ノッチシグナル系による皮膚上皮幹細胞系の制御J演者2012
- Author(s)
  大沢匡毅
- Organizer
  第2回細胞再生医療研究会
- Place of Presentation
  神戸
- Invited
- Data Source
  KAKENHI-PROJECT-24659524
[Presentation] メラノサイト機能遺伝子を同定するための簡便で迅速な遺伝子改変マウス作成法J演者2012
- Author(s)
  大沢匡毅
- Organizer
  第24回日本色素細胞学会学術大会
- Place of Presentation
  長浜
- Invited
- Data Source
  KAKENHI-PROJECT-24659524

1. Yazawa Shigenobu (30392153)

# of Collaborated Projects: 3 results

# of Collaborated Products: 1 results
2. ITO Naoto (20334922)

# of Collaborated Projects: 2 results

# of Collaborated Products: 0 results
3. Sugiyama Makoto (80196774)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
4. NISHIKAWA Shun-Ichi (60127115)

# of Collaborated Projects: 1 results

# of Collaborated Products: 3 results
5. ERA Takumi (00273706)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
6. UEMURA Akiyoshi (30373278)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
7. TOGAWA Atsushi (30359799)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
8. Hozumi Isao (20242430)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
9. 山下潤 (50335288)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
10. 吉田尚弘 (20281090)

# of Collaborated Projects: 1 results

# of Collaborated Products: 1 results
11. 小川峰太郎 (70194454)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
12. 林祐一 (00392366)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
13. 栗田尚佳 (00746315)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
14. 田中真生 (30774252)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
15. 位田雅俊 (70512424)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
16. 酒井洋樹 (40283288)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
17. 西岡恵里

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
18. 藤本哲広

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
19. 高瀬悠太

# of Collaborated Projects: 0 results

# of Collaborated Products: 1 results
20. 佐藤克哉

# of Collaborated Projects: 0 results

# of Collaborated Products: 1 results
21. 長岡仁

# of Collaborated Projects: 0 results

# of Collaborated Products: 1 results

Osawa Masatake 大沢 匡毅

OSAWA Masatake 大沢 匡毅

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Role of Pmell-positive mesothelial cells in the pathogenesis of lymphangioleiomyomatosis.Principal Investigator

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The physiological role of neuropeptide Y in disease progression of vitiligoPrincipal Investigator

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Optimizing targeted protein degradation for the therapeutic applications against melanoma

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Analysis of peripheral infection kinetics of rabies virus by a high-sensitive infection detection system

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Establishment of a novel mouse model of vitiligoPrincipal Investigator

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Research on the molecular mechanism of intracranial calcification and novel therapies

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Generation of genetically modified NC/Nga mice using the CRISPR/Cas9-mediated gene editing systemPrincipal Investigator

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Identification of the important viral factor related to the development of rabies by the gene manipulation in mice

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A rapid melanocyte-specific transgenesis system for phenotype-based gene function discoveryPrincipal Investigator

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迅速かつ簡便な組織特異的遺伝子ノックダウンマウス作成法の開発Principal Investigator

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メラノーマモデルマウスの作製Principal Investigator

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色素幹細胞をモデルとした幹細胞維持機構の解明Principal Investigator

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Molecular Characterization of Melanocyte Stem Cells in the NichePrincipal Investigator

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Osawa Masatake 大沢匡毅

OSAWA Masatake 大沢匡毅