Hisada Takeshi 久田剛志

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HISADA Takeshi 久田剛志

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Researcher Number	10344938
Other IDs	https://orcid.org/0000-0002-3862-1887
Affiliation (Current)	2024: 群馬大学, 大学院保健学研究科, 教授
Affiliation (based on the past Project Information) *help	2018 – 2023: 群馬大学, 大学院保健学研究科, 教授 2015 – 2017: 群馬大学, 医学部附属病院, 講師 2013: 群馬大学, 医学部, 講師
Review Section/Research Field	Principal Investigator Basic Section 54020:Connective tissue disease and allergy-related / Collagenous pathology/Allergology Except Principal Investigator 膠原病・アレルギー・感染症内科学
Keywords	Principal Investigator ω３脂肪酸 / 気管支喘息 / 炎症収束 / resolvin / 脂質メディエーター / レゾルビン / exposome / 環境因子 / ω3脂肪酸 / エイコサペンタエン酸 … More / 重症気管支喘息 / インスリン抵抗性 / 糖尿病 / 重症喘息 / ω-3脂肪酸 / ω－３脂肪酸 / 動物モデル / 肺線維症 … More Except Principal Investigator TNF / Gq / ERK / カルシウム / IL-8 / 気管支平滑筋細胞 / CTGF / 気道リモデリング / 気管支平滑筋 / 樹状細胞 / 気管支喘息 / 気道炎症 / GPCR / OGR1 / プロトン Less

Research on environmental factors that adversely affect the onset and severity of asthma - Pathophysiology and prevention-Principal Investigator
- Principal Investigator
  
  久田剛志
- Project Period (FY)
  2023 – 2025
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Review Section
  
  Basic Section 54020:Connective tissue disease and allergy-related
- Research Institution
  Gunma University
Challenges in Overcoming Severe Asthma ~Research of anti-inflammatory lipid mediators toward drug discovery~Principal Investigator
- Principal Investigator
  
  Hisada Takeshi
- Project Period (FY)
  2018 – 2022
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Review Section
  
  Basic Section 54020:Connective tissue disease and allergy-related
- Research Institution
  Gunma University
Research for anti-inflammatory therapeutic strategy against pulmonary fibrosisPrincipal Investigator
- Principal Investigator
  
  HISADA Takeshi
- Project Period (FY)
  2015 – 2017
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Research Field
  
  Collagenous pathology/Allergology
- Research Institution
  Gunma University
Possible involvements of proton-sensing receptors in alleric airway inflammation and fibrosis
- Principal Investigator
  
  ISHIZUKA TAMOTSU
- Project Period (FY)
  2011 – 2013
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Research Field
  
  膠原病・アレルギー・感染症内科学
- Research Institution
  University of Fukui
  Gunma University

All 2023 2022 2021 2020 2019 2018 2017 2016 2015 2013 2012 2011 Other

All Journal Article Presentation

[Journal Article] Editorial: Pathophysiological and clinical advances in asthmatic inflammation from the nasopharynx to the peripheral airway in the respiratory tract systems2023
- Author(s)
  Koga Yasuhiko、Kamide Yosuke、Hisada Takeshi、Ishizuka Tamotsu
- Journal Title
  
  Frontiers in Pharmacology
  
  Volume: 14 Pages: 1037610-1037610
- DOI
  10.3389/fphar.2023.1037610
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-18K08382
[Journal Article] Design and Synthesis of Cyclopropane Congeners of Resolvin E3, an Endogenous Pro-Resolving Lipid Mediator, as Its Stable Equivalents.2022
- Author(s)
  (2)Arai S, Fujiwara K, Kojima M, Aoki-Saito H, Yatomi M, Saito T, Koga Y, Fukuda H, Watanabe M, Matsunaga S, Hisada T, Shuto S
- Journal Title
  
  The Journal of Organic Chemistry
  
  Volume: 87(15) Issue: 15 Pages: 10501-10508
- DOI
  10.1021/acs.joc.2c01110
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-18K08404, KAKENHI-PROJECT-22K06494, KAKENHI-PROJECT-22K08227, KAKENHI-PROJECT-19H01014, KAKENHI-PROJECT-18K08382, KAKENHI-PROJECT-19K06965, KAKENHI-PROJECT-20K06941, KAKENHI-PROJECT-21K15215
[Journal Article] Perspectives on the Efficacy of Benralizumab for Treatment of Eosinophilic Granulomatosis With Polyangiitis2022
- Author(s)
  Koga Y, Aoki-Saito H, Kamide Y, Sato M, Tsurumaki H, Yatomi M, Ishizuka T, Hisada T.
- Journal Title
  
  Front Pharmacol
  
  Volume: なし Pages: 865318-865318
- DOI
  10.3389/fphar.2022.865318
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-20K12493, KAKENHI-PROJECT-18K08382
[Journal Article] Resolvin E3 ameliorates high‐fat diet‐induced insulin resistance via the phosphatidylinositol‐3‐kinase/Akt signaling pathway in adipocytes2022
- Author(s)
  Shimizu Tomohiko、Saito Tsugumichi、Aoki‐Saito Haruka、Okada Shuichi、Ikeda Hiroyuki、Nakakura Takashi、Fukuda Hayato、Arai Syota、Fujiwara Kouichi、Nakajima Yasuyo、Horiguchi Kazuhiro、Yamada Sayaka、Ishida Emi、Hisada Takeshi、Shuto Satoshi、Yamada Masanobu
- Journal Title
  
  The FASEB Journal
  
  Volume: 36 Issue: 3
- DOI
  10.1096/fj.202100053r
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-18K08382, KAKENHI-PROJECT-19K07257, KAKENHI-PROJECT-20K06941
[Journal Article] Metal-Stimulated Interleukin-6 Production Through a Proton-Sensing Receptor, Ovarian Cancer G Protein-Coupled Receptor 1, in Human Bronchial Smooth Muscle Cells: A Response Inhibited by Dexamethasone2021
- Author(s)
  Kadowaki Maiko、Sato Koichi、Kamio Hisashi、Kumagai Makoto、Sato Rikishi、Nyui Takafumi、Umeda Yukihiro、Waseda Yuko、Anzai Masaki、Aoki-Saito Haruka、Koga Yasuhiko、Hisada Takeshi、Tomura Hideaki、Okajima Fumikazu、Ishizuka Tamotsu
- Journal Title
  
  Journal of Inflammation Research
  
  Volume: Volume 14 Pages: 7021-7034
- DOI
  10.2147/jir.s326964
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-18K08382, KAKENHI-PROJECT-18K08404, KAKENHI-PROJECT-20K08538, KAKENHI-PROJECT-21K08174
[Journal Article] Synthesis of Resolvin E3, a Proresolving Lipid Mediator, and Its Deoxy Derivatives: Identification of 18-Deoxy-resolvin E3 as a Potent Anti-Inflammatory Agent2020
- Author(s)
  Fukuda Hayato、Ikeda Hiroyuki、Muromoto Ryuta、Hirashima Koki、Ishimura Kohei、Fujiwara Koichi、Aoki-Saito Haruka、Hisada Takeshi、Watanabe Mizuki、Ishihara Jun、Matsuda Tadashi、Shuto Satoshi
- Journal Title
  
  The Journal of Organic Chemistry
  
  Volume: 85 Issue: 21 Pages: 14190-14200
- DOI
  10.1021/acs.joc.0c01701
- NAID
  120007168587
- Peer Reviewed / Open Access / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-18K08382, KAKENHI-PROJECT-18K08404, KAKENHI-PROJECT-19K06965, KAKENHI-PROJECT-20K06941, KAKENHI-PROJECT-19H03364
[Journal Article] Prognostic nutritional index as a predictor of mortality in nontuberculous mycobacterial lung disease2020
- Author(s)
  Hachisu Yoshimasa、Murata Keisuke、Takei Kousuke、Tsuchiya Takuma、Tsurumaki Hiroaki、Koga Yasuhiko、Horie Takeo、Takise Atsushi、Hisada Takeshi
- Journal Title
  
  Journal of Thoracic Disease
  
  Volume: 12 Issue: 6 Pages: 3101-3109
- DOI
  10.21037/jtd-20-803
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-18K08382
[Journal Article] Extracellular acidification-induced CXCL8 production through a proton-sensing receptor OGR1 in human airway smooth muscle cells: a response inhibited by dexamethasone.2019
- Author(s)
  M. Kadowaki, H. Yamada, K. Sato, H. Shigemi, Y. Umeda, M. Morikawa, Y. Waseda, M. Anzai, Y. Kamide, H. Aoki-Saito, T. Hisada, F. Okajima, T. Ishizuka
- Journal Title
  
  J. Inflamm. (Lond.)
  
  Volume: 16 Issue: 1 Pages: 4-4
- DOI
  10.1186/s12950-019-0207-1
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-18K07362, KAKENHI-PROJECT-18K08382, KAKENHI-PROJECT-18K08404
[Journal Article] Treatment with Tumor Necrosis Factor-α Inhibitors, History of Allergy, and Hypercalcemia Are Risk Factors of Immune Reconstitution Inflammatory Syndrome in HIV-Negative Pulmonary Tuberculosis Patients2019
- Author(s)
  Hachisu Yoshimasa、Koga Yasuhiko、Kasama Shu、Kaira Kyoichi、Yatomi Masakiyo、Aoki-Saito Haruka、Tsurumaki Hiroaki、Kamide Yosuke、Sunaga Noriaki、Maeno Toshitaka、Ishizuka Tamotsu、Hisada Takeshi
- Journal Title
  
  Journal of Clinical Medicine
  
  Volume: 9 Issue: 1 Pages: 96-96
- DOI
  10.3390/jcm9010096
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-18K08382, KAKENHI-PROJECT-18K08404
[Journal Article] Rapid Effect of Benralizumab for Hypereosinophilia in a Case of Severe Asthma with Eosinophilic Chronic Rhinosinusitis2019
- Author(s)
  Tsurumaki、Matsuyama、Ezawa、Koga、Yatomi、Aoki-Saito、Chikamatsu、Hisada
- Journal Title
  
  Medicina
  
  Volume: 55 Issue: 7 Pages: 336-336
- DOI
  10.3390/medicina55070336
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-18K08382, KAKENHI-PROJECT-17K11374
[Journal Article] Resolvin E3 Attenuates Allergic Airway Inflammation via the interleukin-23-interleukin-17A Pathway2019
- Author(s)
  Sato M, Aoki-Saito H, Fukuda H, Ikeda H, Koga Y, Yatomi M, Tsurumaki H, Maeno T, Saito T, Nakakura T, Mori T, Yanagawa M, Abe M, Sako Y, Dobashi K, Ishizuka T, Yamada M, Shuto S, Hisada T.
- Journal Title
  
  FASEB J.
  
  Volume: Nov;33(11) Issue: 11 Pages: 12750-12759
- DOI
  10.1096/fj.201900283r
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-18K06677, KAKENHI-PROJECT-18K08382, KAKENHI-PROJECT-18K08404, KAKENHI-PROJECT-19K07257, KAKENHI-PROJECT-19H01014, KAKENHI-PROJECT-17K08360, KAKENHI-PROJECT-16K18982, KAKENHI-PROJECT-19H05647
[Journal Article] Possible Serological Markers to Predict Mortality in Acute Exacerbation of Idiopathic Pulmonary Fibrosis2019
- Author(s)
  Hachisu Yoshimasa、Murata Keisuke、Takei Kousuke、Tsuchiya Takuma、Tsurumaki Hiroaki、Koga Yasuhiko、Horie Takeo、Takise Atsushi、Hisada Takeshi
- Journal Title
  
  Medicina
  
  Volume: 55 Issue: 5 Pages: 132-132
- DOI
  10.3390/medicina55050132
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-18K08382
[Journal Article] Bacteriologically Determined <i>De Novo</i> Tuberculosis during Tumor Necrosis Factor-α Inhibitor Therapy2019
- Author(s)
  Takahashi Gen、Kobayashi Hiroyuki、Saito Yasuyuki、Ohsawa Sho、Suzuki Kuniaki、Ishihara Shinichi、Hisada Takeshi
- Journal Title
  
  Intern. Med.
  
  Volume: 58 Issue: 24 Pages: 3593-3596
- DOI
  10.2169/internalmedicine.3054-19
- NAID
  130007761434
- ISSN
  0918-2918, 1349-7235
- Year and Date
  2019-12-15
- Language
  English
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-18K08382
[Journal Article] Roles of Cyclic AMP Response Element Binding Activation in the ERK1/2 and p38 MAPK Signalling Pathway in Central Nervous System, Cardiovascular System, Osteoclast Differentiation and Mucin and Cytokine Production2019
- Author(s)
  Koga Yasuhiko、Tsurumaki Hiroaki、Aoki-Saito Haruka、Sato Makiko、Yatomi Masakiyo、Takehara Kazutaka、Hisada Takeshi
- Journal Title
  
  International Journal of Molecular Sciences
  
  Volume: 20 Issue: 6 Pages: 1346-1346
- DOI
  10.3390/ijms20061346
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-18K08382, KAKENHI-PROJECT-18K08404
[Journal Article] Pirfenidone Improves Familial Idiopathic Pulmonary Fibrosis without Affecting Serum Periostin Levels2019
- Author(s)
  Koga Yasuhiko、Hachisu Yoshimasa、Tsurumaki Hiroaki、Yatomi Masakiyo、Kaira Kyoichi、Ohta Shoichiro、Ono Junya、Izuhara Kenji、Dobashi Kunio、Hisada Takeshi
- Journal Title
  
  Medicina
  
  Volume: 55 Issue: 5 Pages: 161-161
- DOI
  10.3390/medicina55050161
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-18K08382
[Journal Article] Are specialized pro-resolving mediators promising therapeutic agents for severe bronchial asthma?2017
- Author(s)
  Hisada Takeshi、Aoki-Saito Haruka、Koga Yasuhiko
- Journal Title
  
  Journal of Thoracic Disease
  
  Volume: 9 Issue: 11 Pages: 4266-4269
- DOI
  10.21037/jtd.2017.10.116
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-15K09546
[Journal Article] Elemental and immunohistochemical analysis of the lungs and hilar lymph node in a patient with asbestos exposure, a pilot study.2016
- Author(s)
  Koga Y, Satoh T, Kaira K, Koka M, Hisada T, Hirato J, Altan B, Yatomi M, Ono A, Kamide Y, Shimizu Y, Aoki-Saito H, Tsurumaki H, Shimizu K, Mogi A, Ishizuka T, Yamada M, Dobashi K.
- Journal Title
  
  Environ Health Prev Med.
  
  Volume: 6 Issue: 6 Pages: 492-500
- DOI
  10.1007/s12199-016-0576-5
- NAID
  50010159091
- Peer Reviewed / Acknowledgement Compliant / Open Access
- Data Source
  KAKENHI-PROJECT-26461180, KAKENHI-PROJECT-15K19412, KAKENHI-PROJECT-15K09546
[Journal Article] CREB regulates TNF-α-induced GM-CSF secretion via p38 MAPK in human lung fibroblasts2016
- Author(s)
  Koga Y, Hisada T, Ishizuka T, Utsugi M, Ono A, Yatomi M, Kamide Y, Aoki-Saito H, Tsurumaki H, Dobashi K, Yamada M.
- Journal Title
  
  Allergol. Int.
  
  Volume: 65 Issue: 4 Pages: 406-413
- DOI
  10.1016/j.alit.2016.03.006
- NAID
  130005431338
- ISSN
  1323-8930, 1440-1592
- Language
  English
- Peer Reviewed / Acknowledgement Compliant / Open Access
- Data Source
  KAKENHI-PROJECT-15K19412, KAKENHI-PROJECT-15K09546
[Journal Article] Protective role of proton-sensing TDAG8 in lipopolysaccharide-induced acute lung injury.2015
- Author(s)
  H. Tsurumaki, C. Mogi, H. Aoki-Saito, M. Tobo, Y. Kamide, M. Yatomi, K. Sato, K. Dobashi, T. Ishizuka, T. Hisada, M. Yamada, F. Okajima
- Journal Title
  
  Int. J. Mol. Sci.
  
  Volume: 16 Issue: 12 Pages: 28931-28942
- DOI
  10.3390/ijms161226145
- Peer Reviewed / Open Access / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-15K06767, KAKENHI-PROJECT-15K09546, KAKENHI-PROJECT-15K19412, KAKENHI-PROJECT-15H04641, KAKENHI-PROJECT-24500435, KAKENHI-PROJECT-24591349, KAKENHI-PROJECT-25860635
[Journal Article] 17(R)-resolvin D1 ameliorates bleomycin-induced pulmonary fibrosis in mice.2015
- Author(s)
  Yatomi M, Hisada T, Ishizuka T, Koga Y, Ono A, Kamide Y, Seki K, Aoki-Saito H, Tsurumaki H, Sunaga N, Kaira K, Dobashi K, Yamada M, Okajima F.
- Journal Title
  
  PHYSIOLOGICAL REPORTS
  
  Volume: 3 Issue: 12 Pages: 12628-12628
- DOI
  10.14814/phy2.12628
- Peer Reviewed / Acknowledgement Compliant / Open Access / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-15K09546, KAKENHI-PROJECT-26461180, KAKENHI-PROJECT-15K19412, KAKENHI-PROJECT-15H04641, KAKENHI-PROJECT-25860635
[Journal Article] 成人喘息患者における喘息症状および鼻・副鼻腔炎症状のコントロールを把握するためのGスケール問診票の開発2013
- Author(s)
  石塚全、久田剛志、上出庸介、青木悠、関香織、草野元康
- Journal Title
  
  Progress in Medicine
  
  Volume: 33 Pages: 1643-1648
- Data Source
  KAKENHI-PROJECT-23591456
[Journal Article] Proton-sensing ovarian cancer G protein-coupled receptor 1 on dendritic cells is required for airway responses in a murine asthma model2013
- Author(s)
  Aoki H, Mogi C, Hisada T, Kamide Y, Ichimonji I, Tomura H, Tobo M, Sato K, Tsurumaki H, Dobashi K, Mori T, Harada H, Yamada M, Mori M, Ishizuka T, Okajima F
- Journal Title
  
  PLoS ONE
  
  Volume: 8(11) Issue: 11 Pages: e79985-e79985
- DOI
  10.1371/journal.pone.0079985
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-23591456, KAKENHI-PROJECT-23591916, KAKENHI-PROJECT-24500435, KAKENHI-PROJECT-24591349, KAKENHI-PROJECT-25670617, KAKENHI-PROJECT-25860635
[Journal Article] Oxidative stress potentially enhances FcεRI-mediated leukotriene C_4 release dependent on the late-phase increase of intracellular glutathione in mast cells2013
- Author(s)
  Seki K, Hisada T, Kawata T, Kamide Y, Dobashi K, Yamada M, Mori M, Okajima F, Ishizuka T
- Journal Title
  
  Biochem Biophys Res Commun
  
  Volume: 439 Issue: 3 Pages: 357-362
- DOI
  10.1016/j.bbrc.2013.08.081
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-23591456, KAKENHI-PROJECT-23591916, KAKENHI-PROJECT-25670617
[Journal Article] Oxidative stress potentially enhances FceRI-mediated leukotriene C4 release dependent on the late-phase increase of intracellular glutathione in mast cells2013
- Author(s)
  Seki K, Hisada T, Okajima F, Ishizuka T, et al.
- Journal Title
  
  Biochem Biophys Res Commun
  
  Volume: 439 Pages: 357-362
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-23591456
[Journal Article] 呼吸器疾患とGERD Up-to-date2012
- Author(s)
  久田剛志、石塚全、草野元康
- Journal Title
  
  呼吸と循環
  
  Volume: 60 Pages: 953-960
- Data Source
  KAKENHI-PROJECT-23591456
[Journal Article] Intracellular glutathione redox status in human dendritic cells regulates IL-27 production and T-cell polarization2011
- Author(s)
  Kamide Y, Utsugi M, Dobashi K, Ono A, Ishizuka T, Hisada T, Koga Y, Uno K, Hamuro J, Mori M
- Journal Title
  
  Allergy
  
  Volume: 66 Pages: 1183-1192
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-23591456
[Journal Article] Extracellular acidification induces connective tissue growth factor production through proton-sensing receptor OGR1 in human airway smooth musele cells2011
- Author(s)
  Matsuzaki S
- Journal Title
  
  Biochem Biophys Res Commun
  
  Volume: 413 Issue: 4 Pages: 499-503
- DOI
  10.1016/j.bbrc.2011.08.087
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-21390016, KAKENHI-PROJECT-21591158, KAKENHI-PROJECT-22790844, KAKENHI-PUBLICLY-23112503, KAKENHI-PROJECT-23591456, KAKENHI-PROJECT-23591916, KAKENHI-PROJECT-23659029
[Journal Article] Prevalence of asthma symptoms based on the European Community Respiratory Health Survey questionnaire and FENO in university students: gender differences in symptoms and FENO2011
- Author(s)
  Ishizuka T, Matsuzaki S, Aoki H, Yatomi Y, Kamide Y, Hisada T, Tsuburai T, Dobashi K, Ohshima K, Akiyama K, Mori M
- Journal Title
  
  Allergy Asthma Clin Immunol
  
  Volume: 7 Issue: 1 Pages: 15-15
- DOI
  10.1186/1710-1492-7-15
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-23591456
[Journal Article] フルチカゾン/サルメテロール配合剤からブデソニド/ホルモテロール配合剤へ変更し、著明な改善を認めた難治性気管支喘息の1例2011
- Author(s)
  松崎晋一、石塚全、久田剛志、森昌朋
- Journal Title
  
  Therapeutic Research
  
  Volume: 32 Pages: 231-235
- Data Source
  KAKENHI-PROJECT-23591456
[Presentation] ResolvinE1、E2、E3のアレルギー性気道炎症に対する効果の検討2022
- Author(s)
  ResolvinE1、E2、E3のアレルギー性気道炎症に対する効果の検討佐藤真季子, 青木悠, 鶴巻寛朗, 矢冨正清, 古賀康彦, 砂長則明, 石塚全, 土橋邦生, 周東智, 前野敏孝, 久田剛志
- Organizer
  日本呼吸器学会
- Data Source
  KAKENHI-PROJECT-18K08382
[Presentation] 喘息発症・重症化のメカニズムはどこまで分かったか　喘息発症・重症化と環境因子2022
- Author(s)
  久田剛志
- Organizer
  日本呼吸器学会
- Data Source
  KAKENHI-PROJECT-18K08382
[Presentation] Resolvin E3の細胞内シグナル伝達経路に及ぼす影響の解析2022
- Author(s)
  Resolvin E3の細胞内シグナル伝達経路に及ぼす影響の解析矢冨正清, 古賀康彦, 齋藤悠, 佐藤真季子, 山口公一, 山口彩, 伊藤優志, 三浦陽介, 鶴巻寛朗, 原健一郎, 砂長則明, 前野敏孝, 周東智, 久田剛志
- Organizer
  日本呼吸器学会
- Data Source
  KAKENHI-PROJECT-18K08382
[Presentation] アレルギー疾患における免疫細胞による病態形成とその解明　Resolvin E3のマクロファージ内シグナル伝達経路に及ぼす影響の解析2022
- Author(s)
  矢冨正清 , 古賀康彦, 齋藤悠, 佐藤真季子, 山口公一, 山口彩, 三浦陽介, 鶴巻寛朗, 原健一郎, 砂長則明, 前野敏孝, 周東智, 久田剛志
- Organizer
  日本アレルギー学会
- Data Source
  KAKENHI-PROJECT-18K08382
[Presentation] Resolvin E3(RvE3)誘導体の生物学的安定性の解析について2021
- Author(s)
  齋藤悠, 佐藤真季子, 古賀康彦, 矢冨正清, 鶴巻寛朗, 齋藤従道, 山口彩, 山口公一, 澤田友里, 原健一郎, 砂長則明, 前野敏孝, 石塚全, 福田隼, 周東智, 久田剛志
- Organizer
  日本アレルギー学会
- Data Source
  KAKENHI-PROJECT-18K08382
[Presentation] アレルギー性炎症の新規誘導/収束メカニズム　Resolvinの線維化増殖因子に及ぼす影響の解析2021
- Author(s)
  矢冨正清, 古賀康彦, 齋藤悠, 佐藤真季子, 山口公一, 山口彩, 鶴巻寛朗, 原健一郎, 砂長則明, 前野敏孝, 周東智, 久田剛志
- Organizer
  日本アレルギー学会
- Data Source
  KAKENHI-PROJECT-18K08382
[Presentation] 脂質メディエーターResolvinの抗線維化効果の解析2021
- Author(s)
  矢冨正清, 古賀康彦, 齋藤悠, 佐藤真季子, 鶴巻寛朗, 原健一郎, 砂長則明, 前野敏孝, 周東智, 久田剛志
- Organizer
  日本呼吸器学会
- Data Source
  KAKENHI-PROJECT-18K08382
[Presentation] ResolvinE1,E3のアレルギー性気道炎症に対する効果の検討2021
- Author(s)
  佐藤真季子, 齋藤悠, 鶴巻寛朗, 矢冨正清, 古賀康彦, 砂長則明, 石塚全, 土橋邦生, 周東智, 前野敏孝, 久田剛志
- Organizer
  日本呼吸器学会
- Data Source
  KAKENHI-PROJECT-18K08382
[Presentation] ResolvinE3誘導体の樹状細胞に対する抗炎症性作用の解析2021
- Author(s)
  齋藤悠, 佐藤真季子, 矢冨正清, 古賀康彦, 鶴巻寛朗, 齋藤従道, 宇野翔吾, 若松郁生, 花里千春, 増田友美, 澤田友里, 原健一郎, 砂長則明, 前野敏孝, 周東智, 久田剛志
- Organizer
  日本呼吸器学会
- Data Source
  KAKENHI-PROJECT-18K08382
[Presentation] Rerationship between interstitial pneumonia related systemic sclerosis and esophageal motility abnormalities2020
- Author(s)
  Kenichiro Hara, Kouichi Yamaguchi, Masakiyo Yatomi, Hiroaki Tsurumaki, Takeshi Hisada, Toshitaka Maeno
- Organizer
  European Respiratory Society 2020
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-18K08382
[Presentation] Resolvin E3 reduces profibrotic factor production from macrophages leading to tissue homeostasis2020
- Author(s)
  Masakiyo Yatomi, Yasuhiko Koga, Haruka Saito, Makiko Sato, Hiroaki Tsurumaki, Kenichiro Hara, Noriaki Sunaga, Toshitaka Maeno, Hiroyuki Ikeda, Hayato Fukuda, Shouta Arai, Koichi Fujiwara, Satoshi Shuto, Takeshi Hisada
- Organizer
  European Respiratory Society 2020
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-18K08382
[Presentation] Resolvin E1 and E3 dampens asthmatic inflammation in a murine model2020
- Author(s)
  Makiko Sato, Haruka Aoki-Saito, Masakiyo Yatomi, Hiroaki Tsurumaki, Yasuhiko Koga, Noriaki Sunaga, Toshitaka Maeno, Kunio Dobashi, Satoshi Shuto, Masataka Yamada, Takeshi Hisada
- Organizer
  European Respiratory Society 2020
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-18K08382
[Presentation] T cell death associated gene 8 mediates MUC5AC expression in acidic conditions2019
- Author(s)
  Hiroaki Tsurumaki, Haruka Saito-Aoki, Chihiro Mogi, Koichi Sato, Takashi Nakakura, Yasuhiko Koga, Masakiyo Yatomi, Makiko Sato, Toshitaka Maeno, Kunio Dobashi, Fumikazu Okajima, Takeshi Hisada
- Organizer
  European Respiratory Society 2019, Madrid, Spain
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-18K08382
[Presentation] Resolvin E3 dampens asthmatic inflammation in a murine model through IL-23 pathway2019
- Author(s)
  Makiko Sato, Haruka Aoki-Saito, Hayato Fukuda, Hiroyuki Ikeda, Yasuhiko Koga, Masakiyo Yatomi, Hiroaki Tsurumaki, Kazutaka Takehara, Takashi Nakakura, Tetsuya Mori, Tsugumichi Saito, Kunio Dobashi, Masanobu Yamada, Satoshi Shuto, Takeshi Hisada
- Organizer
  European Respiratory Society 2019, Madrid, Spain
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-18K08382
[Presentation] 17(R)-resolvinD1 mediates a pathway involving the transcription factor c-Fos to reduce bleomycin-induced pulmonary fibrosis in mice.2018
- Author(s)
  Masakiyo Yatomi, Takeshi Hisada, Yoshimasa Hachisu, Yusuke Tsukagoshi, Norimitsu Kasahara, Makiko Sato, Hiroaki Tsurumaki, Haruka Saito, Kenichiro Hara, Yasuhiko Koga, Noriaki Sunaga, Toshitaka Maeno, Kunio Dobashi
- Organizer
  European Respiratory Society 2018, Paris, France
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-18K08382
[Presentation] Resolvin E3 attenuates asthmatic inflammation in a murine model of House Dust Mite (HDM) -induced airway inflammation2018
- Author(s)
  Makiko Sato*, Haruka Aoki-Saito, Hayato Fukuda, Yasuhiko Koga, Masakiyo Yatomi, Hiroaki Tsurumaki, Takashi Nakakura, Masanobu Yamada, Satoshi Shuto, Takeshi Hisada
- Organizer
  Asia Pacific Society of Respirology 2018, Taipei, Taiwan
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-18K08382
[Presentation] 17（R）-ResolvinD1の肺線維症モデルにおける線維化抑制作用の検討2018
- Author(s)
  矢冨正清、齋藤悠、佐藤真季子、鶴巻寛朗、笠原礼光、蜂巣克昌、塚越優介、原健一郎、小野昭浩、古賀康彦、解良恭一、砂長則明、前野敏孝、土橋邦生、久田剛志
- Organizer
  第58回日本呼吸器学会学術講演会
- Data Source
  KAKENHI-PROJECT-15K09546
[Presentation] Resolvin E3 attenuates House Dust Mite (HDM) -induced asthmatic inflammation in a murine model2018
- Author(s)
  Makiko Sato, Haruka Aoki-Saito, Hayato Fukuda, Hiroyuki Ikeda, Yasuhiko Koga, Masakiyo Yatomi, Hiroaki Tsurumaki , Yoshimasa Hachisu, Takashi Nakakura, Tetsuya Mori, Kunio Dobashi, Masanobu Yamada, Satoshi Shuto, Takeshi Hisada
- Organizer
  European Respiratory Society 2018, Paris, France
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-18K08382
[Presentation] Treatment of Severe Asthma, BT and Phenotype-targeted therapy2017
- Author(s)
  Takeshi Hisada
- Organizer
  Chinese Association of Chest Physician(CACP) Annual Congress 2017, Chendu, Sichuan, China
- Invited / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-15K09546
[Presentation] Absence of proton-sensing TDAG8 protects against ovalbumin-induced allergic airway inflammation2017
- Author(s)
  Hiroaki Tsurumaki, Chihiro Mogi, Haruka Saito-Aoki, Koichi Sato, Takashi Nakakura, Masakiyo Yatomi, Yasuhiko Koga, Yoshimasa Hachisu, Akihiro Ono, Kunio Dobashi, Fumikazu Okajima, Takeshi Hisada
- Organizer
  ERS International Congress 2017, Milan, Italy
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-15K09546
[Presentation] Bronchial Themoplasty ~from the perspective of basic research~2017
- Author(s)
  Takeshi Hisada
- Organizer
  The 27th Congress of Interasma Japan/North Asia, Kumamoto, Japan
- Invited / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-15K09546
[Presentation] 17(R)-resolvinD1 improves MMP-9/TIMP-1 imbalance leading to amelioration of pulmonary fibrosis in mice.2016
- Author(s)
  Masakiyo Yatomi, Takeshi Hisada, Yoshimasa Hachisu, Yasuyuki Saito, Hiroaki Tsurumaki, Yosuke Kamide, Haruka Aoki-Saito, Yasuhiko Koga, Akihiro Ono, Kunio Dobashi, Tamotsu Ishizuka, Masanobu Yamada, Fumikazu Okajima
- Organizer
  ERS International Congress 2016（国際学会）
- Place of Presentation
  London, United Kingdom
- Year and Date
  2016-09-03
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-15K09546
[Presentation] Proton-sensing TDAG8 exhibits the protective role in lipopolysaccharide-induced acute lung injury.2016
- Author(s)
  Tsurumaki H, Hisada T, Mogi C, Saito-Aoki H, Yatomi M, Kamide Y, Tobo M, Sato K, Koga Y, Ono A, Dobashi K, Ishizuka T, Yamada M, Okajima F.
- Organizer
  ERS International Congress 2016（国際学会）
- Place of Presentation
  London, United Kingdom
- Year and Date
  2016-09-03
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-15K09546
[Presentation] Absence of proton-sensing OGR1 protects against house dust mite-induced allergic airway inflammation.2016
- Author(s)
  Haruka Saito, Takeshi Hisada, Chihiro Mogi, Tsurumaki Hiroaki, Masakiyo Yatomi, Yosuke Kamide, Akihiro Ono, Yasuhiko Koga, Kunio Dobashi, Tamotsu Ishizuka, Fumikazu Okajima, Masanobu Yamada
- Organizer
  ERS International Congress 2016（国際学会）
- Place of Presentation
  London, United Kingdom
- Year and Date
  2016-09-03
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-15K09546
[Presentation] 17(R)-resolvin D1 ameliorates bleomycin-induced pulmonary fibrosis in mice via decreasing MCP-1 mRNA2015
- Author(s)
  Masakiyo Yatomi, Takeshi Hisada, Yasuhiko Koga, Akihiro Ono, Yosuke Kamide, Haruka Aoki, Tsurumaki Hiroaki, Kaori Seki, Noriaki Sunaga, Kyoichi Kaira, Tamotsu Ishizuka, Kunio Dobashi, Masanobu Yamada, Fumikazu Okajima
- Organizer
  ERS International Congress 2015
- Place of Presentation
  Amsterdam, Netherlands
- Year and Date
  2015-09-26
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-15K09546
[Presentation] Resolvins and Allergic Inflammation (Symposium)2015
- Author(s)
  Takeshi Hisada
- Organizer
  The 25th Congress of Interasma Japan/North Asia
- Place of Presentation
  Yokohama, Japan
- Year and Date
  2015-09-03
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-15K09546
[Presentation] 喘息コントロール評価のためのGスケール問診票の有用性2013
- Author(s)
  石塚全,久田剛志,上出庸介,青木悠,関香織,小野昭浩,古賀康彦,土橋邦生,本定千知,住田泰之,安斎正樹,門脇麻衣子,森川美羽,梅田幸寛,飴嶋慎吾,石崎武志,草野元康,森昌朋
- Organizer
  第25回日本アレルギー学会春季臨床大会
- Place of Presentation
  横浜市
- Year and Date
  2013-05-11
- Data Source
  KAKENHI-PROJECT-23591456
[Presentation] 長期管理薬で治療中の気管支喘息患者における喘息症状,鼻・副鼻腔炎症状と胃食道逆流症状との関連2013
- Author(s)
  石塚全,久田剛志,上出庸介,青木悠,関香織,西岡正樹,解良恭一,岩崎靖樹,小野昭浩,古賀康彦,砂長則明,土橋邦生,草野元康,森昌朋
- Organizer
  第53回日本呼吸器学会学術講演会
- Place of Presentation
  東京
- Year and Date
  2013-04-21
- Data Source
  KAKENHI-PROJECT-23591456
[Presentation] 喘息患者における胃食道逆流症状,鼻副鼻腔炎症状,喘息症状の相互関係2012
- Author(s)
  石塚全,久田剛志,上出庸介,小野昭浩,古賀康彦,岩崎靖樹,砂長則明,青木悠,関香織,土橋邦生,森昌朋
- Organizer
  第62回日本アレルギー学会秋季学術大会
- Place of Presentation
  大阪市
- Year and Date
  2012-12-01
- Data Source
  KAKENHI-PROJECT-23591456
[Presentation] 難治性喘息に対する新規治療法としての白血球除去療法の可能性2012
- Author(s)
  石塚全,久田剛志,鶴巻寛朗,解良恭一,岩崎靖樹,小野昭浩,古賀康彦,砂長則明,土橋邦生,森昌朋
- Organizer
  第109回日本内科学会総会講演会
- Place of Presentation
  京都市
- Year and Date
  2012-04-14
- Data Source
  KAKENHI-PROJECT-23591456
[Presentation] 難治性喘息患者におけるPulse LCAP療法の安全性と有効性に関する検討2012
- Author(s)
  石塚全,久田剛志,上出庸介,青木悠,松崎晋一,鶴巻寛朗,解良恭一,岩崎靖樹,宇津木光克,小野昭浩,古賀康彦,砂長則明,土橋邦生,森昌朋
- Organizer
  第52回日本呼吸器学会学術講演会
- Place of Presentation
  神戸市
- Year and Date
  2012-04-20
- Data Source
  KAKENHI-PROJECT-23591456
[Presentation] ミニシンポジウム3 好酸球性肺炎など.嗅覚障害と篩骨洞病変を有する気管支喘息症例の臨床的検討2011
- Author(s)
  石塚全,久田剛志,小野昭浩,古賀康彦,鶴巻寛朗,松崎晋一,関香織,青木悠,上出庸介,矢冨正清,森宗昌,土橋邦生,森昌朋
- Organizer
  第23回日本アレルギー学会春季臨床大会
- Place of Presentation
  千葉市
- Year and Date
  2011-05-14
- Data Source
  KAKENHI-PROJECT-23591456
[Presentation] プロトン感知性Ｇ蛋白質共役型受容体OGR1の気管支喘息における関与について2011
- Author(s)
  青木　悠、茂木千尋、久田剛志、石塚　全、岡島史和、ほか
- Organizer
  第61回日本アレルギー学会秋季学術大会
- Place of Presentation
  グランドプリンスホテル新高輪（東京都）
- Data Source
  KAKENHI-PROJECT-23591456
[Presentation] 大学生の喘息様症状と呼気NO濃度における性差2011
- Author(s)
  石塚全,松崎晋一,青木悠,矢冨正清,上出庸介,久田剛志,粒来崇博,土橋邦生,秋山一男,森昌朋
- Organizer
  第61回日本アレルギール学会秋季学術大会
- Place of Presentation
  東京
- Year and Date
  2011-11-12
- Data Source
  KAKENHI-PROJECT-23591456
[Presentation] Efficacy of high-dose leukocytapheresis using extracorporeal circulation through a large leukocyte-removal filter column in patients with refractory asthma2011
- Author(s)
  Ishizuka T, Koike A, Hatori M, Matsuzaki S, Kamide Y, Aoki H, Hisada T, Tsurumaki H, Ono A, Koga Y, Dobashi K, Suzuki K, Mori M
- Organizer
  European Respiratory Society International Congress 2011
- Place of Presentation
  アムステルダム
- Year and Date
  2011-09-27
- Data Source
  KAKENHI-PROJECT-23591456
[Presentation] アンケート調査に基づく大学生の喘息症状、既往、呼気NO濃度に関する検討2011
- Author(s)
  石塚全,久田剛志,松崎晋一,青木悠,矢冨正清,上出庸介,土橋邦生,大島喜八,森昌朋
- Organizer
  第21回国際喘息学会日本・北アジア部会
- Place of Presentation
  岐阜市
- Year and Date
  2011-07-02
- Data Source
  KAKENHI-PROJECT-23591456
[Presentation] オフライン法による呼気NO濃度測定値を利用した喘息有症率調査2011
- Author(s)
  石塚全,松崎晋一,青木悠,矢冨正清,上出庸介,鶴巻寛朗,今井久雄,解良恭一,小野昭浩,古賀康彦,岩崎靖樹,砂長則明,久田剛志,土橋邦生,森昌朋
- Organizer
  第51回日本呼吸器学会学術講演会
- Place of Presentation
  東京
- Year and Date
  2011-04-22
- Data Source
  KAKENHI-PROJECT-23591456
[Presentation] プロトン感知性Gタンパク質共役型受容体OGR1KOマウスにおける気管支喘息モデルの解析
- Author(s)
  青木　悠、茂木千尋、久田剛志、石塚　全、ほか
- Organizer
  第62回日本アレルギー学会秋季学術大会
- Place of Presentation
  大阪国際会議場
- Data Source
  KAKENHI-PROJECT-23591456

1. OKAJIMA Fumikazu (30142748)

# of Collaborated Projects: 2 results

# of Collaborated Products: 10 results
2. ISHIZUKA TAMOTSU (50302477)

# of Collaborated Projects: 1 results

# of Collaborated Products: 20 results
3. YATOMI Masakiyo (60784105)

# of Collaborated Projects: 1 results

# of Collaborated Products: 7 results
4. SAITO Haruka (80447268)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
5. SATOH Takahiro

# of Collaborated Projects: 0 results

# of Collaborated Products: 1 results
6. KOGA Yasuhiko

# of Collaborated Projects: 0 results

# of Collaborated Products: 2 results
7. ABE Mitsuhiro

# of Collaborated Projects: 0 results

# of Collaborated Products: 1 results
8. KAIRA Kyoichi

# of Collaborated Projects: 0 results

# of Collaborated Products: 1 results
9. 青木悠

# of Collaborated Projects: 0 results

# of Collaborated Products: 9 results
10. 佐藤幸市

# of Collaborated Projects: 0 results

# of Collaborated Products: 2 results
11. 土橋邦生

# of Collaborated Projects: 0 results

# of Collaborated Products: 1 results

Hisada Takeshi 久田 剛志

HISADA Takeshi 久田 剛志

Research Projects

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Co-Researchers

Research on environmental factors that adversely affect the onset and severity of asthma - Pathophysiology and prevention-Principal Investigator

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Challenges in Overcoming Severe Asthma ~Research of anti-inflammatory lipid mediators toward drug discovery~Principal Investigator

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Research for anti-inflammatory therapeutic strategy against pulmonary fibrosisPrincipal Investigator

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Possible involvements of proton-sensing receptors in alleric airway inflammation and fibrosis

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[Journal Article] Editorial: Pathophysiological and clinical advances in asthmatic inflammation from the nasopharynx to the peripheral airway in the respiratory tract systems2023

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[Journal Article] Design and Synthesis of Cyclopropane Congeners of Resolvin E3, an Endogenous Pro-Resolving Lipid Mediator, as Its Stable Equivalents.2022

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[Journal Article] Perspectives on the Efficacy of Benralizumab for Treatment of Eosinophilic Granulomatosis With Polyangiitis2022

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[Journal Article] Resolvin E3 ameliorates high‐fat diet‐induced insulin resistance via the phosphatidylinositol‐3‐kinase/Akt signaling pathway in adipocytes2022

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[Journal Article] Metal-Stimulated Interleukin-6 Production Through a Proton-Sensing Receptor, Ovarian Cancer G Protein-Coupled Receptor 1, in Human Bronchial Smooth Muscle Cells: A Response Inhibited by Dexamethasone2021

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[Journal Article] Synthesis of Resolvin E3, a Proresolving Lipid Mediator, and Its Deoxy Derivatives: Identification of 18-Deoxy-resolvin E3 as a Potent Anti-Inflammatory Agent2020

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NAID

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[Journal Article] Prognostic nutritional index as a predictor of mortality in nontuberculous mycobacterial lung disease2020

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[Journal Article] Extracellular acidification-induced CXCL8 production through a proton-sensing receptor OGR1 in human airway smooth muscle cells: a response inhibited by dexamethasone.2019

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[Journal Article] Treatment with Tumor Necrosis Factor-α Inhibitors, History of Allergy, and Hypercalcemia Are Risk Factors of Immune Reconstitution Inflammatory Syndrome in HIV-Negative Pulmonary Tuberculosis Patients2019

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[Journal Article] Rapid Effect of Benralizumab for Hypereosinophilia in a Case of Severe Asthma with Eosinophilic Chronic Rhinosinusitis2019

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Hisada Takeshi 久田剛志

HISADA Takeshi 久田剛志